Sumeet Jain, Debasish Mohapatra, S. Satpathi, S. Senapati
{"title":"An Update on Infection and Cancer","authors":"Sumeet Jain, Debasish Mohapatra, S. Satpathi, S. Senapati","doi":"10.5530/OGH.2018.7.1.2","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.2","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127907929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Saharan, S. Dalal, Mahavir Singh, Chisel Bhatia, R. Sen
Gastrointestinal stromal tumors (GIST) are relatively rare and often present with vague symptoms. Their first clinical manifestation as acute abdomen due to perforation is extremely rare. We report a rare case of spontaneous perforation of exophytic gastrointestinal stromal tumor (GIST) causing perforation of jejunum. A 61 year, male patient presented with symptoms of acute abdomen. After evaluation, a laparotomy was performed, where perforation of a tumor in the jejunum was found. The perforated part along with the tumor was resected and the histopathological examination showed that the tumor was GIST. In emergency setting the patients with perforation peritonitis, a diagnosis of spontaneous perforation of GIST though rare should be kept in mind specially in elderly patients.
{"title":"Spontaneous perforation of GIST of the Small Intestine: A Rare Cause of Perforation Peritonitis","authors":"A. Saharan, S. Dalal, Mahavir Singh, Chisel Bhatia, R. Sen","doi":"10.5530/OGH.2017.6.2.16","DOIUrl":"https://doi.org/10.5530/OGH.2017.6.2.16","url":null,"abstract":"Gastrointestinal stromal tumors (GIST) are relatively rare and often present with vague symptoms. Their first clinical manifestation as acute abdomen due to perforation is extremely rare. We report a rare case of spontaneous perforation of exophytic gastrointestinal stromal tumor (GIST) causing perforation of jejunum. A 61 year, male patient presented with symptoms of acute abdomen. After evaluation, a laparotomy was performed, where perforation of a tumor in the jejunum was found. The perforated part along with the tumor was resected and the histopathological examination showed that the tumor was GIST. In emergency setting the patients with perforation peritonitis, a diagnosis of spontaneous perforation of GIST though rare should be kept in mind specially in elderly patients.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126316930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Debashish Bhattacharjee, S. Mondal, Goutam Dey, S. Biswas
Introduction: Primary plasmacytoma of the thyroid gland is a rare disease. Extramedullary plasmacytoma (EMP) comprises 3-5% of all plasma cell neoplasm. Case report: A 57-yearsold female presented with a large thyroid swelling involving the left lobe and isthmus, firm in consistency and moved a little with deglutition. CT scan revealed a large solid tumor (9.5 cm in greatest dimension) affecting thyroid gland. CT scan report gave differential diagnoses of plasmacytoma and metastatic carcinoma. FNAC revealed hypercellular smears composed of plasma cells with eccentrically placed nuclei and perinuclear hoff. Hematological work up and other relevant investigations including urine for Bence Jones protein ruled out multiple myeloma or other plasma cell dyscrasias. Subsequent histopathological examination and IHC (immunohistochemistry) confirmed the diagnosis of primary plasmacytoma of thyroid. Discussion: EMP can present with elevated anti thyroid antibodies and can be associated with lymphocytic thyroiditis; however, in our patient these findings were not present.
{"title":"Primary Plasmacytoma of Thyroid Gland—an Interesting Case Diagnosed By FNAC","authors":"Debashish Bhattacharjee, S. Mondal, Goutam Dey, S. Biswas","doi":"10.5530/OGH.2017.6.2.24","DOIUrl":"https://doi.org/10.5530/OGH.2017.6.2.24","url":null,"abstract":"Introduction: Primary plasmacytoma of the thyroid gland is a rare disease. Extramedullary plasmacytoma (EMP) comprises 3-5% of all plasma cell neoplasm. Case report: A 57-yearsold female presented with a large thyroid swelling involving the left lobe and isthmus, firm in consistency and moved a little with deglutition. CT scan revealed a large solid tumor (9.5 cm in greatest dimension) affecting thyroid gland. CT scan report gave differential diagnoses of plasmacytoma and metastatic carcinoma. FNAC revealed hypercellular smears composed of plasma cells with eccentrically placed nuclei and perinuclear hoff. Hematological work up and other relevant investigations including urine for Bence Jones protein ruled out multiple myeloma or other plasma cell dyscrasias. Subsequent histopathological examination and IHC (immunohistochemistry) confirmed the diagnosis of primary plasmacytoma of thyroid. Discussion: EMP can present with elevated anti thyroid antibodies and can be associated with lymphocytic thyroiditis; however, in our patient these findings were not present.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115198598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"KAI-1 ad p53 expression in Odontogenic cysts: An Immuno-histochemical Marker Study","authors":"A. Nayyar, N. Patil, M. Chaudhary, V. Wadhwan","doi":"10.5530/ogh.2017.6.2.14","DOIUrl":"https://doi.org/10.5530/ogh.2017.6.2.14","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123185455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Synovial sarcoma is an aggressive malignant neoplasm arising from mesenchymal tissue representing 7-10% of all soft tissue sarcomas. Typically, it presents in children and young adults aged 13-35 years of age. These are usually located in the extremities, most commonly around the knee. Paraspinal region is a rare site of synovial sarcoma and thus requires a high index of suspicion for timely diagnosis. Here, we discuss such a rare case of paraspinal synovial sarcoma.
{"title":"A Rare Case of Synovial Sarcoma Presenting in Paraspinal Region","authors":"Kaalindi Singh, P. Thakur, Mukesh K. Sharma","doi":"10.5530/OGH.2017.6.2.25","DOIUrl":"https://doi.org/10.5530/OGH.2017.6.2.25","url":null,"abstract":"Synovial sarcoma is an aggressive malignant neoplasm arising from mesenchymal tissue representing 7-10% of all soft tissue sarcomas. Typically, it presents in children and young adults aged 13-35 years of age. These are usually located in the extremities, most commonly around the knee. Paraspinal region is a rare site of synovial sarcoma and thus requires a high index of suspicion for timely diagnosis. Here, we discuss such a rare case of paraspinal synovial sarcoma.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132448036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajeev Lakkavalli Krishnappa, G. Kanakasetty, Suresh Babu Mallekavu Chikkadasappa, S. Rao
Acute promyelocytic leukaemia presenting with bony lesions alongside medullary involvement is rare with anecdotal reports having noted this manifestation in a newly diagnosed case. We here report an infrequent presentation of a young adult male presenting solely with multiple axial and pelvic bone lesions initially, with the initial impression being a lymphoma /infiltrative lesion. This is a case report that reiterates the need for prompt diagnosis and a thorough evaluation for early treatment, especially since this is a curable malignancy.
{"title":"Acute Promyelocytic Leukaemia(APML) in an Adult Patient Presenting with Multiple Lytic Bony Lesions – The First of its Kind – A Case Report with Review of Literature","authors":"Rajeev Lakkavalli Krishnappa, G. Kanakasetty, Suresh Babu Mallekavu Chikkadasappa, S. Rao","doi":"10.5530/ogh.2017.6.2.23","DOIUrl":"https://doi.org/10.5530/ogh.2017.6.2.23","url":null,"abstract":"Acute promyelocytic leukaemia presenting with bony lesions alongside medullary involvement is rare with anecdotal reports having noted this manifestation in a newly diagnosed case. We here report an infrequent presentation of a young adult male presenting solely with multiple axial and pelvic bone lesions initially, with the initial impression being a lymphoma /infiltrative lesion. This is a case report that reiterates the need for prompt diagnosis and a thorough evaluation for early treatment, especially since this is a curable malignancy.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117250946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The rising incidence of incidentally detected adrenal masses reflects the ever growing use of radiologic investigations specially CT scans and MRI. The differential diagnosis is a long list which includes adenoma, myelolipoma, cyst, lipoma, pheochromocytoma, adrenal cancer, metastatic cancer, hyperplasia, and tuberculosis.[5] However rarely a schwannoma is considered in the list of provisional diagnosis. CT scan is often the first line of investigation of choice which along with endocrinological workup can point towards diagnosis. But none of them are 100% specific. Since the posterior mediastinum is anatomically in proximity to the adrenal area, a tumour in such a region can mimic an adrenal mass as was in our case. We herein report such an unusual case where a posterior mediastinal mass was found intraoperatively instead of a ‘presumed’ adrenal mass as suggested by preoperative radiological investigations!
{"title":"Mass in the Adrenal Region: Not Always of Adrenal Origin: A Diagnostic Dilemma","authors":"Suvendu Maji, M. Saha, S. Sahu","doi":"10.5530/OGH.2017.6.2.20","DOIUrl":"https://doi.org/10.5530/OGH.2017.6.2.20","url":null,"abstract":"The rising incidence of incidentally detected adrenal masses reflects the ever growing use of radiologic investigations specially CT scans and MRI. The differential diagnosis is a long list which includes adenoma, myelolipoma, cyst, lipoma, pheochromocytoma, adrenal cancer, metastatic cancer, hyperplasia, and tuberculosis.[5] However rarely a schwannoma is considered in the list of provisional diagnosis. CT scan is often the first line of investigation of choice which along with endocrinological workup can point towards diagnosis. But none of them are 100% specific. Since the posterior mediastinum is anatomically in proximity to the adrenal area, a tumour in such a region can mimic an adrenal mass as was in our case. We herein report such an unusual case where a posterior mediastinal mass was found intraoperatively instead of a ‘presumed’ adrenal mass as suggested by preoperative radiological investigations!","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127636489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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