M. Shalina, M. Yarmolinskaya, E. A. Netreba, A. K. Beganova
BACKGROUND: Patients with endometriosis-associated pain syndrome in combination with anxiety or depression have lower treatment effectiveness and satisfaction with both the disease itself and the pain syndrome compared to patients with pain syndrome but without depression or anxiety. AIM: The aim of the study is to assess the relationship between psychosocial status and endometriosis-associated pain syndrome in patients with different phenotypes of endometriosis using pain assessment scales, psychosocial state assessment scales, and quality of life assessment scales. MATERIALS AND METHODS: We examined 81 patients using a number of questionnaires: Visual Analogue Scale, Numeric Rating Scale, Hospital Anxiety and Depression Scale, Beck Depression Scale, Spielberger State-Trait Anxiety Inventory, and Short Form-36 quality of life assessment. The patients were divided into three groups: isolated adenomyosis (n = 39), adenomyosis combined with external genital endometriosis (n = 21), and the control group (n = 21). RESULTS: Our study has shown that patients with adenomyosis combined with external genital endometriosis had the highest scores on all questionnaires for assessing anxiety and depression, as well as a low quality of life in general, which significantly differed from those in the control group (p 0.05). The results in the group of women with isolated adenomyosis are not so unambiguous and, overall, somewhat better than in the group of patients with adenomyosis combined with external genital endometriosis, but significantly worse compared to the control group. When assessing the severity of dysmenorrhea, higher scores were also found in the group of women with adenomyosis combined with external genital endometriosis: 6.64 2.11 cm (Visual Analogue Scale) and 6.9 2.05 cm (Numeric Rating Scale), while in the group of women with isolated adenomyosis, the scores were 5.29 1.9 cm and 5.83 1.72 cm, respectively (p = 0.028). Women in the control group had no pain syndrome. CONCLUSIONS: Poor mental and physical health scores obtained in this study in women with external genital endometriosis dictate the need for an objective and multicomponent assessment of the psycho-emotional status in patients, followed by complex treatment and team management with related specialists.
{"title":"Psycho-emotional status in patients with endometriosis-associated pain syndrome in various disease phenotypes","authors":"M. Shalina, M. Yarmolinskaya, E. A. Netreba, A. K. Beganova","doi":"10.17816/jowd346683","DOIUrl":"https://doi.org/10.17816/jowd346683","url":null,"abstract":"BACKGROUND: Patients with endometriosis-associated pain syndrome in combination with anxiety or depression have lower treatment effectiveness and satisfaction with both the disease itself and the pain syndrome compared to patients with pain syndrome but without depression or anxiety. \u0000AIM: The aim of the study is to assess the relationship between psychosocial status and endometriosis-associated pain syndrome in patients with different phenotypes of endometriosis using pain assessment scales, psychosocial state assessment scales, and quality of life assessment scales. \u0000MATERIALS AND METHODS: We examined 81 patients using a number of questionnaires: Visual Analogue Scale, Numeric Rating Scale, Hospital Anxiety and Depression Scale, Beck Depression Scale, Spielberger State-Trait Anxiety Inventory, and Short Form-36 quality of life assessment. The patients were divided into three groups: isolated adenomyosis (n = 39), adenomyosis combined with external genital endometriosis (n = 21), and the control group (n = 21). \u0000RESULTS: Our study has shown that patients with adenomyosis combined with external genital endometriosis had the highest scores on all questionnaires for assessing anxiety and depression, as well as a low quality of life in general, which significantly differed from those in the control group (p 0.05). The results in the group of women with isolated adenomyosis are not so unambiguous and, overall, somewhat better than in the group of patients with adenomyosis combined with external genital endometriosis, but significantly worse compared to the control group. When assessing the severity of dysmenorrhea, higher scores were also found in the group of women with adenomyosis combined with external genital endometriosis: 6.64 2.11 cm (Visual Analogue Scale) and 6.9 2.05 cm (Numeric Rating Scale), while in the group of women with isolated adenomyosis, the scores were 5.29 1.9 cm and 5.83 1.72 cm, respectively (p = 0.028). Women in the control group had no pain syndrome. \u0000CONCLUSIONS: Poor mental and physical health scores obtained in this study in women with external genital endometriosis dictate the need for an objective and multicomponent assessment of the psycho-emotional status in patients, followed by complex treatment and team management with related specialists.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79443325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tkhai, S. Chepanov, O. Arzhanova, O. Bespalova, S. Selkov
The important role of human chorionic gonadotropin in pregnancy suggests the occurrence of reproductive disorders due to the circulation of specific antibodies, especially in early pregnancy, which can lead to a cascade of pathological reactions such as implantation failure, placentation, trophoblast invasion, and ultimately fetal rejection. The lack of knowledge and the complexity of diagnosing and treating this autoimmune pathology in reproductive medicine and obstetrics negatively affects both the outcomes of each individual pregnancy and the demographic situation as a whole. This review article highlights the main ideas about the causes of human chorionic gonadotropin antibody occurrence, the pathological mechanisms, the reproductive and obstetric complications associated with human chorionic gonadotropin autoantibodies, diagnostic methods, and therapeutic approaches.
{"title":"Autosensitization to human chorionic gonadotropin: etiology, role in reproductive loss, and approaches to therapy","authors":"D. Tkhai, S. Chepanov, O. Arzhanova, O. Bespalova, S. Selkov","doi":"10.17816/jowd114793","DOIUrl":"https://doi.org/10.17816/jowd114793","url":null,"abstract":"The important role of human chorionic gonadotropin in pregnancy suggests the occurrence of reproductive disorders due to the circulation of specific antibodies, especially in early pregnancy, which can lead to a cascade of pathological reactions such as implantation failure, placentation, trophoblast invasion, and ultimately fetal rejection. The lack of knowledge and the complexity of diagnosing and treating this autoimmune pathology in reproductive medicine and obstetrics negatively affects both the outcomes of each individual pregnancy and the demographic situation as a whole. This review article highlights the main ideas about the causes of human chorionic gonadotropin antibody occurrence, the pathological mechanisms, the reproductive and obstetric complications associated with human chorionic gonadotropin autoantibodies, diagnostic methods, and therapeutic approaches.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82584381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Stress urinary incontinence in women is a common condition that can develop at a young age and, even with mild severity, disrupts the quality of life. The first line of treatment for stress urinary incontinence is pelvic floor muscle training, which is the most effective in biofeedback mode. The low effectiveness of self-study is often associated with irregular and incorrect exercise. AIM: The aim of this study was to evaluate the effectiveness of remote pelvic floor muscle training using the Tyulpan laser vaginal simulator under medical supervision in the treatment of mild and moderate stress urinary incontinence in women of reproductive and perimenopausal age, and to develop a predictive model for evaluating the effectiveness of treatment by this method. MATERIALS AND METHODS: We examined 48 patients aged 41.3 6.8 years (2655) with complaints of mild to moderate stress urinary incontinence. After general clinical and special studies (analysis of seven-day urination diaries, Kings questionnaire and Pelvic Organ Prolapse / Urinary Incontinence Sexual Questionnaire (PISQ-12), urethrovesical segment ultrasound examination), a remote course of treatment was started using the Tyulpan laser vaginal simulator under medical supervision via videoconference for 35 patients within three months. The participants were re-examined one, three and four to six months after the start of the pelvic floor muscle training course. RESULTS: The training course was fully completed by 25 participants. After one month of remote pelvic floor muscle training, according to urination diaries, a decrease in the number of stress urinary incontinence episodes was noted by 64.0% of patients and the absence of stress urinary incontinence episodes by 28.0% of patients (p 0.001); after three months of remote pelvic floor muscle training, by 32.0% and 68.0% of patients, respectively (p 0.001). A negative cough test after one month was detected in 62.5% of the participants (p = 0.002) and, after four to six months with the continuation of independent pelvic floor muscle training, in 81.9% of patients (p = 0.003). According to the ROC-analysis, the absence of stress urinary incontinence episodes was predicted when the amplitude of the simulator laser beam was greater than or equal to 90 cm (sensitivity 84.0%, specificity 96.0%; p 0.001). Distance learning under medical supervision had a positive impact on the quality of life and relationships with a partner and improved the womens psychological well-being (p 0.001). CONCLUSIONS: Remote pelvic floor muscle training is effective in women of reproductive and perimenopausal age with mild to moderate stress urinary incontinence who are able to contract their pelvic floor muscles and perform regular exercises. The effectiveness of the training course is 68.0% according to urination diaries and 81.9% according to the cough test. The absence of stress urinary incontinence episodes is predicted when the amplitude of the simulat
{"title":"Remote pelvic floor muscle training in the treatment of stress urinary incontinence in women","authors":"E. Rusina, Maria M. Zhevlakova","doi":"10.17816/jowd430311","DOIUrl":"https://doi.org/10.17816/jowd430311","url":null,"abstract":"BACKGROUND: Stress urinary incontinence in women is a common condition that can develop at a young age and, even with mild severity, disrupts the quality of life. The first line of treatment for stress urinary incontinence is pelvic floor muscle training, which is the most effective in biofeedback mode. The low effectiveness of self-study is often associated with irregular and incorrect exercise. \u0000AIM: The aim of this study was to evaluate the effectiveness of remote pelvic floor muscle training using the Tyulpan laser vaginal simulator under medical supervision in the treatment of mild and moderate stress urinary incontinence in women of reproductive and perimenopausal age, and to develop a predictive model for evaluating the effectiveness of treatment by this method. \u0000MATERIALS AND METHODS: We examined 48 patients aged 41.3 6.8 years (2655) with complaints of mild to moderate stress urinary incontinence. After general clinical and special studies (analysis of seven-day urination diaries, Kings questionnaire and Pelvic Organ Prolapse / Urinary Incontinence Sexual Questionnaire (PISQ-12), urethrovesical segment ultrasound examination), a remote course of treatment was started using the Tyulpan laser vaginal simulator under medical supervision via videoconference for 35 patients within three months. The participants were re-examined one, three and four to six months after the start of the pelvic floor muscle training course. \u0000RESULTS: The training course was fully completed by 25 participants. After one month of remote pelvic floor muscle training, according to urination diaries, a decrease in the number of stress urinary incontinence episodes was noted by 64.0% of patients and the absence of stress urinary incontinence episodes by 28.0% of patients (p 0.001); after three months of remote pelvic floor muscle training, by 32.0% and 68.0% of patients, respectively (p 0.001). A negative cough test after one month was detected in 62.5% of the participants (p = 0.002) and, after four to six months with the continuation of independent pelvic floor muscle training, in 81.9% of patients (p = 0.003). According to the ROC-analysis, the absence of stress urinary incontinence episodes was predicted when the amplitude of the simulator laser beam was greater than or equal to 90 cm (sensitivity 84.0%, specificity 96.0%; p 0.001). Distance learning under medical supervision had a positive impact on the quality of life and relationships with a partner and improved the womens psychological well-being (p 0.001). \u0000CONCLUSIONS: Remote pelvic floor muscle training is effective in women of reproductive and perimenopausal age with mild to moderate stress urinary incontinence who are able to contract their pelvic floor muscles and perform regular exercises. The effectiveness of the training course is 68.0% according to urination diaries and 81.9% according to the cough test. The absence of stress urinary incontinence episodes is predicted when the amplitude of the simulat","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90950967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article is dedicated to the outstanding obstetrician V.V. Abramchenko. His medical, scientific and teaching activities were inextricably linked with the Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott, Saint Petersburg, Russia. He shared his rich experience and knowledge with his students, and the legacy that he left behind will continue to be a shining beacon for many generations of doctors to come.
{"title":"In memory of Professor Valery V. Abramchenko (1938–2011)","authors":"Tatyana U. Kuzminykh, Igor Nikolaenkov","doi":"10.17816/jowd492326","DOIUrl":"https://doi.org/10.17816/jowd492326","url":null,"abstract":"This article is dedicated to the outstanding obstetrician V.V. Abramchenko. His medical, scientific and teaching activities were inextricably linked with the Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott, Saint Petersburg, Russia. He shared his rich experience and knowledge with his students, and the legacy that he left behind will continue to be a shining beacon for many generations of doctors to come.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83726467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Bezhenar, A. Plekhanov, Fedor V. Bezhenar, Tatiana A. Epifanova
This article presents a review of the current literature on the problem of omission and prolapse of the internal genitalia in women. Patients diagnosed with pelvic organ prolapse need pelvic floor plastic surgery. Currently, in spite of the extensive experience in managing this category of patients, there is still no single and unambiguous approach to the choice of surgical treatment tactics. This review describes the latest information on the etiopathogenesis of pelvic floor supporting apparatus lesions, namely, systemic connective tissue dysplasia as the main development factor. Prospective development of genetic and immunohistochemical marker diagnosis is the key to individual selection of treatment options for this multidisciplinary problem. The results of interventions are characterized by extreme variability in terms of both effectiveness and the frequency of intra- and postoperative complications. The treatment of rare forms of prolapse after surgery for rectal cancer also raises many questions. The current multitude of types of surgical interventions for genital prolapse and variants of pelvic floor defect closure is constantly being modified. To date, there is no universal treatment option, and all available techniques have both advantages and disadvantages, as well as limited application due to the risk of somatic complications, high recurrence rate, and the need for expensive equipment and a highly qualified surgeon. New research is needed, taking into account the current knowledge about the cellular and molecular mechanism of the lesion of the pelvic floor supporting apparatus. All of this will improve the methods of correction of pelvic organ prolapse in both typical and rare forms caused by iatrogenic factors. As a result, this may lead to an improvement in the quality of life of such patients.
{"title":"Topical issues of surgical treatment of pelvic floor dysfunction. A literature review","authors":"V. Bezhenar, A. Plekhanov, Fedor V. Bezhenar, Tatiana A. Epifanova","doi":"10.17816/jowd101408","DOIUrl":"https://doi.org/10.17816/jowd101408","url":null,"abstract":"This article presents a review of the current literature on the problem of omission and prolapse of the internal genitalia in women. Patients diagnosed with pelvic organ prolapse need pelvic floor plastic surgery. Currently, in spite of the extensive experience in managing this category of patients, there is still no single and unambiguous approach to the choice of surgical treatment tactics. \u0000This review describes the latest information on the etiopathogenesis of pelvic floor supporting apparatus lesions, namely, systemic connective tissue dysplasia as the main development factor. Prospective development of genetic and immunohistochemical marker diagnosis is the key to individual selection of treatment options for this multidisciplinary problem. The results of interventions are characterized by extreme variability in terms of both effectiveness and the frequency of intra- and postoperative complications. The treatment of rare forms of prolapse after surgery for rectal cancer also raises many questions. The current multitude of types of surgical interventions for genital prolapse and variants of pelvic floor defect closure is constantly being modified. To date, there is no universal treatment option, and all available techniques have both advantages and disadvantages, as well as limited application due to the risk of somatic complications, high recurrence rate, and the need for expensive equipment and a highly qualified surgeon. \u0000New research is needed, taking into account the current knowledge about the cellular and molecular mechanism of the lesion of the pelvic floor supporting apparatus. All of this will improve the methods of correction of pelvic organ prolapse in both typical and rare forms caused by iatrogenic factors. As a result, this may lead to an improvement in the quality of life of such patients.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86566879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. V. Zhestkova, Eduard K. Aylamazyan, Tatyana U. Kuzminykh, N. V. Marchenko
BACKGROUND:Intrahepatic cholestasis of pregnancy occupies a leading place in the structure of hepatoses associated with pregnancy. As with many other diseases that debut during gestation, all the symptoms of intrahepatic cholestasis of pregnancy disappear after delivery and have no consequences for the mother, unlike, for example, acute fatty degeneration of the liver. However, the fetal prognosis remains serious due to the high incidence of preterm birth and the toxic effect of bile components on the developing fetus, which both lead to perinatal complications. Especially fatal is the situation when intrahepatic cholestasis of pregnancy is combined with intrauterine infection, placental insufficiency, severe preeclampsia, diabetes mellitus, or other extragenital pathology. Until recently, it was believed that the only correct solution for intrahepatic cholestasis of pregnancy development was early delivery. Only in recent decades, attempts have been made to therapeutic correction of this pathology in order to prolong pregnancy to full term and reduce the frequency of perinatal complications. So far, tangible results have been achieved with the use of ursodeoxycholic acid preparations and the introduction of efferent methods of therapy into obstetric practice. AIM:The aim of this study was to develop optimal schemes for pathogenetic therapy of intrahepatic cholestasis of pregnancy using hepatoprotectors from the ursodeoxycholic acid group, as well as ademetionine, essential phospholipids, and membrane plasmapheresis. MATERIALS AND METHODS:This study included 150 pregnant women with intrahepatic cholestasis of pregnancy. Group I (n= 50) comprised patients who were treated only with ursodeoxycholic acid. Group II (n= 50) included individuals who were given combined drug therapy with ursodeoxycholic acid, ademetionine, and essential phospholipids. Group III (n= 50) consisted of women whose treatment included efferent therapies (membrane plasmapheresis) in combination with ursodeoxycholic acid or ademetionine preparations. All pregnant women before the start of therapy were determined the blood levels of bile acids, total and direct bilirubin, and transaminases (alanine aminotransferase, aspartate aminotransferase). Blood parameters were monitored once every seven days. All the patients were also monitored for the condition of the fetus (fetometry, dopplerometry, cardiotocography). RESULTS:The use of ursodeoxycholic acid not combined with other hepatoprotectors (group I) was possible only in cases of increased blood levels of bile acids of not more than 40 mmol/L, preparations of ademetionine and essential phospholipids as monotherapy being ineffective. With an increase in the blood levels of bile acids of more than 40 mmol/L and transaminases by two to three or more times from the upper limit of the norm (group II), the most effective was the combined use of ursodeoxycholic acid, ademetionine and essential phospholipid preparations. The most sign
{"title":"Principles of treatment of intrahepatic cholestasis of pregnant women","authors":"N. V. Zhestkova, Eduard K. Aylamazyan, Tatyana U. Kuzminykh, N. V. Marchenko","doi":"10.17816/jowd321213","DOIUrl":"https://doi.org/10.17816/jowd321213","url":null,"abstract":"BACKGROUND:Intrahepatic cholestasis of pregnancy occupies a leading place in the structure of hepatoses associated with pregnancy. As with many other diseases that debut during gestation, all the symptoms of intrahepatic cholestasis of pregnancy disappear after delivery and have no consequences for the mother, unlike, for example, acute fatty degeneration of the liver. However, the fetal prognosis remains serious due to the high incidence of preterm birth and the toxic effect of bile components on the developing fetus, which both lead to perinatal complications. Especially fatal is the situation when intrahepatic cholestasis of pregnancy is combined with intrauterine infection, placental insufficiency, severe preeclampsia, diabetes mellitus, or other extragenital pathology. Until recently, it was believed that the only correct solution for intrahepatic cholestasis of pregnancy development was early delivery. Only in recent decades, attempts have been made to therapeutic correction of this pathology in order to prolong pregnancy to full term and reduce the frequency of perinatal complications. So far, tangible results have been achieved with the use of ursodeoxycholic acid preparations and the introduction of efferent methods of therapy into obstetric practice. \u0000AIM:The aim of this study was to develop optimal schemes for pathogenetic therapy of intrahepatic cholestasis of pregnancy using hepatoprotectors from the ursodeoxycholic acid group, as well as ademetionine, essential phospholipids, and membrane plasmapheresis. \u0000MATERIALS AND METHODS:This study included 150 pregnant women with intrahepatic cholestasis of pregnancy. Group I (n= 50) comprised patients who were treated only with ursodeoxycholic acid. Group II (n= 50) included individuals who were given combined drug therapy with ursodeoxycholic acid, ademetionine, and essential phospholipids. Group III (n= 50) consisted of women whose treatment included efferent therapies (membrane plasmapheresis) in combination with ursodeoxycholic acid or ademetionine preparations. All pregnant women before the start of therapy were determined the blood levels of bile acids, total and direct bilirubin, and transaminases (alanine aminotransferase, aspartate aminotransferase). Blood parameters were monitored once every seven days. All the patients were also monitored for the condition of the fetus (fetometry, dopplerometry, cardiotocography). \u0000RESULTS:The use of ursodeoxycholic acid not combined with other hepatoprotectors (group I) was possible only in cases of increased blood levels of bile acids of not more than 40 mmol/L, preparations of ademetionine and essential phospholipids as monotherapy being ineffective. With an increase in the blood levels of bile acids of more than 40 mmol/L and transaminases by two to three or more times from the upper limit of the norm (group II), the most effective was the combined use of ursodeoxycholic acid, ademetionine and essential phospholipid preparations. The most sign","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78142497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Bezhenar, Elena V. Rogatinskaya, Daria T. Dyachenko, Dariya V. Fedosova
This review of modern literature presents data on the effect of endometriosis on the course of pregnancy and childbirth. It covers studies related to the relationship of pregnancy complications such as preeclampsia and hypertension with previous treatment of endometriosis. Attention is also paid to complications of the postpartum period and the frequency of premature birth. The directions of further development of the problem, which is pregnancy in patients with endometriosis, are determined.
{"title":"Pregnancy and childbirth in patients with endometriosis","authors":"V. Bezhenar, Elena V. Rogatinskaya, Daria T. Dyachenko, Dariya V. Fedosova","doi":"10.17816/jowd109303","DOIUrl":"https://doi.org/10.17816/jowd109303","url":null,"abstract":"This review of modern literature presents data on the effect of endometriosis on the course of pregnancy and childbirth. It covers studies related to the relationship of pregnancy complications such as preeclampsia and hypertension with previous treatment of endometriosis. Attention is also paid to complications of the postpartum period and the frequency of premature birth. The directions of further development of the problem, which is pregnancy in patients with endometriosis, are determined.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"36 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90459846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna V. Andreeva, A. N. Baranov, Elena V. Kazakevich, Oleg F. Kozyr, G. O. Samburov, Tamara A. Tuchina, Sergey K. Dyachkov
This article presents information about Nikolay Alexandrovich Sosnin, a pioneer of endoscopic operative gynecology in the Arkhangelsk region. On March 10, 2022, he would have turned 70 years old. For more than 30 years, he was the head of the gynecological department of N.A. Semashko Northern Medical Clinical Center (Arkhangelsk, Russia). N.A. Sosnin introduced laparoscopic technology into the practice of gynecologists in the Arkhangelsk region.
{"title":"In memory of Nikolay Alexandrovich Sosnin, a pioneer of endoscopic operative gynecology in the Arkhangelsk region (to the 70th anniversary of his birth and the 100th anniversary of N.A. Semashko Northern Medical Clinical Center, Arkhangelsk, Russia)","authors":"Anna V. Andreeva, A. N. Baranov, Elena V. Kazakevich, Oleg F. Kozyr, G. O. Samburov, Tamara A. Tuchina, Sergey K. Dyachkov","doi":"10.17816/jowd321541","DOIUrl":"https://doi.org/10.17816/jowd321541","url":null,"abstract":"This article presents information about Nikolay Alexandrovich Sosnin, a pioneer of endoscopic operative gynecology in the Arkhangelsk region. On March 10, 2022, he would have turned 70 years old. For more than 30 years, he was the head of the gynecological department of N.A. Semashko Northern Medical Clinical Center (Arkhangelsk, Russia). N.A. Sosnin introduced laparoscopic technology into the practice of gynecologists in the Arkhangelsk region.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90868903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endometriosis is one of the most common gynecological diseases in women of reproductive age, which is characterized by a relapsing course. The recurrence rate varies greatly among literary sources. This review covers symptoms and types of endometriosis, laboratory tests, options for hormonal therapy, as well as features of surgical approaches that may be associated with the disease recurrence risk. The aim of this article was to analyze and summarize current literature on the definition of endometriosis recurrence, risk factors and prevention strategy. Despite advances in the study of various mechanisms for the development of endometriosis and the use of combined treatment, a high recurrence rate remains an unsolved problem for this disease. All of this underscores the need to develop new methods for early diagnosis and treatment, taking into account the risk group and a personalized approach.
{"title":"Recurrent genital endometriosis: risk factors and possible prevention strategy","authors":"V.O. Semenova, M. Yarmolinskaya","doi":"10.17816/jowd125109","DOIUrl":"https://doi.org/10.17816/jowd125109","url":null,"abstract":"Endometriosis is one of the most common gynecological diseases in women of reproductive age, which is characterized by a relapsing course. The recurrence rate varies greatly among literary sources. This review covers symptoms and types of endometriosis, laboratory tests, options for hormonal therapy, as well as features of surgical approaches that may be associated with the disease recurrence risk. The aim of this article was to analyze and summarize current literature on the definition of endometriosis recurrence, risk factors and prevention strategy. Despite advances in the study of various mechanisms for the development of endometriosis and the use of combined treatment, a high recurrence rate remains an unsolved problem for this disease. All of this underscores the need to develop new methods for early diagnosis and treatment, taking into account the risk group and a personalized approach.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79158873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND:Uterine fibroids are increasingly diagnosed in patients of reproductive age. Combined hormonal contraceptives provide reliable protection against unwanted pregnancy and help to reduce or eliminate various clinical manifestations of uterine fibroids. In practice, obstetrician-gynecologists have barriers to prescribing combined hormonal contraceptives to patients with uterine fibroids. AIM:The aim of this work was to study the features of the clinical approach of obstetrician-gynecologists to the management of patients with uterine fibroids interested in combined hormonal contraception. MATERIALS AND METHODS:The method of voluntary anonymous questioning was applied to 366 obstetrician-gynecologists. The work experience of 62.1% (n= 227) of doctors was 10 years or more. The questionnaire included questions about various aspects of the use of combined hormonal contraceptives for contraception in women with uterine fibroids. RESULTS:Only every second (47.5%;n= 174) obstetrician-gynecologist correctly assigns uterine fibroids to the first category of acceptability for combined hormonal contraceptives. The presence of an asymptomatic submucous myomatous node (FIGO 12) or dysmenorrhea in women with uterine fibroids is considered by 29.0% (n= 106) and 5.7% (n= 21) of obstetrician-gynecologists, respectively, as a contraindication to the use of combined hormonal contraceptives. Every ninth participant (11.4%;n= 42) believes that the presence of uterine fibroids limits the duration of use of combined hormonal contraceptives for contraception to 15 years. Almost half (45.6%;n= 167) of the respondents believe that combined hormonal contraceptives have various effects on uterine fibroids (cause regression or growth of fibroids, increase the risk of new fibroids). More than half (53.3%;n= 195) of the respondents are not informed about the reduction in the risk of developing uterine fibroids when using combined hormonal contraceptives for five years or more. CONCLUSIONS:In the analyzed cohort of experienced obstetrician-gynecologists, we identified their barriers to prescribing combined hormonal contraceptives for contraception for women with uterine fibroids. Those are incomplete awareness of the acceptance criteria for combined hormonal contraceptives and insufficient awareness of the lack of effect of combined hormonal contraceptives on the size of existing myomatous nodes and a decrease in the risk of developing uterine fibroids when using combined hormonal contraceptives for five or more years.
{"title":"Use of combined hormonal contraceptives in women with uterine fibroids: opinions of practitioners","authors":"N. Aganezova, S. Aganezov, Maria M. Shilo","doi":"10.17816/jowd321247","DOIUrl":"https://doi.org/10.17816/jowd321247","url":null,"abstract":"BACKGROUND:Uterine fibroids are increasingly diagnosed in patients of reproductive age. Combined hormonal contraceptives provide reliable protection against unwanted pregnancy and help to reduce or eliminate various clinical manifestations of uterine fibroids. In practice, obstetrician-gynecologists have barriers to prescribing combined hormonal contraceptives to patients with uterine fibroids. \u0000AIM:The aim of this work was to study the features of the clinical approach of obstetrician-gynecologists to the management of patients with uterine fibroids interested in combined hormonal contraception. \u0000MATERIALS AND METHODS:The method of voluntary anonymous questioning was applied to 366 obstetrician-gynecologists. The work experience of 62.1% (n= 227) of doctors was 10 years or more. The questionnaire included questions about various aspects of the use of combined hormonal contraceptives for contraception in women with uterine fibroids. \u0000RESULTS:Only every second (47.5%;n= 174) obstetrician-gynecologist correctly assigns uterine fibroids to the first category of acceptability for combined hormonal contraceptives. The presence of an asymptomatic submucous myomatous node (FIGO 12) or dysmenorrhea in women with uterine fibroids is considered by 29.0% (n= 106) and 5.7% (n= 21) of obstetrician-gynecologists, respectively, as a contraindication to the use of combined hormonal contraceptives. Every ninth participant (11.4%;n= 42) believes that the presence of uterine fibroids limits the duration of use of combined hormonal contraceptives for contraception to 15 years. Almost half (45.6%;n= 167) of the respondents believe that combined hormonal contraceptives have various effects on uterine fibroids (cause regression or growth of fibroids, increase the risk of new fibroids). More than half (53.3%;n= 195) of the respondents are not informed about the reduction in the risk of developing uterine fibroids when using combined hormonal contraceptives for five years or more. \u0000CONCLUSIONS:In the analyzed cohort of experienced obstetrician-gynecologists, we identified their barriers to prescribing combined hormonal contraceptives for contraception for women with uterine fibroids. Those are incomplete awareness of the acceptance criteria for combined hormonal contraceptives and insufficient awareness of the lack of effect of combined hormonal contraceptives on the size of existing myomatous nodes and a decrease in the risk of developing uterine fibroids when using combined hormonal contraceptives for five or more years.","PeriodicalId":16623,"journal":{"name":"Journal of obstetrics and women's diseases","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85230266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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