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Novel Technique for Extracting Metallic Debris from a Broken Reamer-Irrigator-Aspirator-2 Head within the Intramedullary Canal. 从髓内管内铰-灌-吸-2头破碎中提取金属碎片的新技术。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6446
Devin Q John, David A Patch, Walt R Smith, Doriann M Alcaide, Jonathan H Quade

Introduction: The reamer-irrigator-aspirator (RIA) is safe and effective for harvesting intramedullary autograft and tissue for culture. However, mechanical complications such as reamer head dissociation with retained intramedullary debris have been previously reported.

Case report: Techniques to remove the metallic debris have been described, but are technically challenging and inefficient. The authors provide a novel technique to aid in the removal of loose debris using a laparoscopic suction device.

Conclusion: We have utilized this instrument on multiple occasions, and it has demonstrated itself to be safe, reliable, and effective at removing all debris.

介绍:扩钳-冲洗-吸引器(RIA)是一种安全有效的自体髓内移植物和培养组织采集方法。然而,机械并发症,如铰刀头分离与保留髓内碎片之前已经报道过。病例报告:已经描述了去除金属碎片的技术,但技术上具有挑战性且效率低下。作者提供了一种新的技术,以帮助去除松散的碎片使用腹腔镜吸装置。结论:我们已在多个场合使用该仪器,证明其安全、可靠、有效地清除了所有碎片。
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引用次数: 0
Functional and Radiological Outcome of Arthroscopic Meniscal Repair for Discoid Meniscus. 关节镜下半月板盘状半月板修复的功能和影像学结果。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6542
B Ram Shankar, G Vignesh, Gowtham Senguttuvan

Introduction: Discoid meniscus (DM) is a congenital anomaly of the meniscus form that predisposes individuals to symptomatic DM, especially in the lateral meniscus. Arthroscopic meniscal repair has emerged as the preferred treatment approach for symptomatic cases, prioritizing meniscal preservation to maintain knee joint integrity and function.

Objectives: The purpose of this study was to evaluate the radiological and functional outcome of arthroscopic meniscal repair of DM using validated clinical scores and post-operative imaging.

Materials and methods: A prospective observational study was conducted on 40 patients aged 10-40 years at Sree Balaji Medical College and Hospital. Arthroscopic meniscal repair consisted of an all-inside procedure, an inside-out procedure, or an outside-in procedure, based on the involved location. Functional outcomes of the post-operation have been determined, as well as the pre-operative rating systems of the Lysholm Knee Score on functionality. Minimum follow-up of the patients (24 months into the future) was followed to verify short-term healing, besides checking the long-term effects of the patients at earlier patients.

Results: The majority of patients were male (60%) and presented with symptoms such as knee pain and thud (43.33%). The mean pre-operative Lysholm score was 56.20, which significantly improved to 91.29 postoperatively (P < 0.001). According to the Lysholm score grading, 83.3% of patients achieved good outcomes, 3.33% excellent, and 13.3% fair. No poor outcomes were observed. Radiology showed satisfactory joint presentation in all cases.

Conclusion: Arthroscopic meniscal repair for DM leads to significant functional improvement and satisfactory radiological outcomes. This technique is particularly beneficial for young, active individuals, contributing to joint preservation and reducing the risk of early osteoarthritis. Further long-term studies with larger cohorts are recommended to confirm sustained benefits and monitor degenerative changes.

盘状半月板(DM)是一种先天性的半月板畸形,使个体易患有症状的DM,尤其是外侧半月板。关节镜下半月板修复已成为有症状病例的首选治疗方法,优先保留半月板以保持膝关节的完整性和功能。目的:本研究的目的是通过有效的临床评分和术后影像来评估关节镜下半月板修复DM的放射学和功能结果。材料与方法:对Sree Balaji医学院住院的40例10 ~ 40岁患者进行前瞻性观察研究。关节镜半月板修复包括全内手术、由内向外手术或由外向内手术,取决于受累部位。已经确定了术后的功能结果,以及术前Lysholm膝关节功能评分系统。对患者进行最小随访(未来24个月)以验证短期愈合,并在早期患者中检查患者的长期效果。结果:患者以男性居多(60%),以膝关节疼痛、重击等症状为主(43.33%)。术前Lysholm评分平均值为56.20,术后Lysholm评分为91.29,差异有统计学意义(P < 0.001)。根据Lysholm评分分级,83.3%的患者获得良好结果,3.33%的患者获得优异结果,13.3%的患者获得一般结果。未观察到不良结果。放射学显示所有病例关节表现满意。结论:关节镜下半月板修复术治疗糖尿病患者功能明显改善,影像学结果满意。这项技术对年轻,活跃的个体特别有益,有助于关节保护和降低早期骨关节炎的风险。建议采用更大的队列进行进一步的长期研究,以确认持续的益处并监测退行性变化。
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引用次数: 0
Platelet-Rich Plasma Injections are Associated with Higher Resource Utilization and Surgical Escalation Compared with Corticosteroids in Lateral Elbow Tendinopathy. 与皮质类固醇相比,富血小板血浆注射在肘关节外侧肌腱病变中具有更高的资源利用率和手术升级率。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6534
Aamir Shahzad, Haji Bahar Ali, Zim Warda Hassan, Syed Amir Ali Shah, Abeeha Oza, Wiqqas Jamil

Introduction: Epicondylitis (lateral and medial) is a common tendinopathy that impairs function and quality of life. Corticosteroid injections (CSI) provide rapid but often short-lived symptom relief, while platelet-rich plasma (PRP) is used as a biologic alternative aimed at tendon regeneration. Comparative effectiveness between PRP and CSI remains uncertain in real-world settings.

Materials and methods: We conducted a retrospective cohort study using de-identified electronic health records from the TriNetX Network (2010-2025). Adults ≥18 years with coded epicondylitis and subsequent PRP or CSI were included. Cohorts were 1:1 propensity-score matched on demographics and comorbidities (age, sex, race, type 2 diabetes, obesity, hypothyroidism, nicotine dependence). Outcomes were assessed over a period of 1 year after the index event and included repeat or new medication, opioid exposure, long-term opioid initiation, visits to the emergency department (ED), functional diagnoses (stiffness, weakness, mobility), physical therapy (PT) utilization, and surgical escalation. Hazard ratios (HRs) and risk ratios were estimated.

Results: After matching, 1,064 PRP patients were compared with 1,064 CSI patients. PRP was associated with higher hazards of repeat or new medication (HR 1.33; 95% CI 1.18-1.50; RR 1.21), opioid exposure (HR 1.48; 95% CI 1.20-1.83; RR 1.43), PT utilization (HR 1.52; 95% CI 1.27-1.81; RR 1.41), joint stiffness (HR 1.64; 95% CI 1.04-2.59; RR 1.63), dependence on mobility aids (HR 3.63; 95% CI 1.80-7.31; RR 3.60), and surgical escalation (HR 2.57; 95% CI 1.19-5.56; RR 2.30). No significant differences were observed for ED visits, long-term opioid initiation, abnormal gait, muscle weakness, or contracture.

Conclusion: In this large, multi-institutional real-world cohort, PRP was associated with higher short-term utilization and treatment failure risks compared with CSI. While randomized trials suggest mid-term benefits of PRP, our findings highlight an efficacy-effectiveness gap, likely reflecting heterogeneity in PRP protocols and patient selection. Clinicians should counsel patients about the potential for early symptom flare and higher downstream resource use when considering PRP.

简介:上髁炎(外侧和内侧)是一种常见的肌腱病变,损害功能和生活质量。皮质类固醇注射(CSI)提供快速但通常是短暂的症状缓解,而富血小板血浆(PRP)被用作旨在肌腱再生的生物替代品。PRP和CSI在现实环境中的相对有效性仍不确定。材料和方法:我们使用来自TriNetX网络(2010-2025)的去识别电子健康记录进行了一项回顾性队列研究。年龄≥18岁、患有隐蔽性上髁炎并随后出现PRP或CSI的成人纳入研究。队列在人口统计学和合并症(年龄、性别、种族、2型糖尿病、肥胖、甲状腺功能减退、尼古丁依赖)上的倾向评分匹配为1:1。在指标事件发生后的1年内评估结果,包括重复或新的药物治疗、阿片类药物暴露、长期阿片类药物起始、急诊就诊(ED)、功能诊断(僵硬、无力、活动能力)、物理治疗(PT)的使用和手术升级。评估风险比(hr)和风险比。结果:配对后,1064例PRP患者与1064例CSI患者进行比较。PRP与重复或新药物治疗(HR 1.33; 95% CI 1.18-1.50; RR 1.21)、阿片类药物暴露(HR 1.48; 95% CI 1.20-1.83; RR 1.43)、PT利用(HR 1.52; 95% CI 1.27-1.81; RR 1.41)、关节僵硬(HR 1.64; 95% CI 1.04-2.59; RR 1.63)、对活动辅助工具的依赖(HR 3.63; 95% CI 1.80-7.31; RR 3.60)和手术升级(HR 2.57; 95% CI 1.19-5.56; RR 2.30)相关。在急诊科就诊、长期阿片类药物起始、步态异常、肌肉无力或挛缩方面没有观察到显著差异。结论:在这个大型的、多机构的真实世界队列中,与CSI相比,PRP与更高的短期利用率和治疗失败风险相关。虽然随机试验表明PRP的中期益处,但我们的研究结果强调了疗效差距,可能反映了PRP方案和患者选择的异质性。在考虑PRP时,临床医生应告知患者早期症状爆发的可能性和更高的下游资源使用。
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引用次数: 0
Recurrent Giant Cell Tumor of the Carpal Bones in an Adult Male Managed by En-bloc Excision, Extended Curettage, Bone Grafting, and all-Kirschner Wire Fixation: A Rare Case Report and Literature Review. 成年男性腕骨巨细胞瘤复发经整体切除、扩大刮除、植骨及全克氏针固定:一例罕见病例报告及文献回顾。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6482
Ramesh Govindharaaju, K Kumaran Chettiar, Hariharan Selvam, Sharafuddeen Mammu, Jerin P Rajan

Introduction: Giant cell tumor of bone (GCTB) is a benign but locally aggressive lesion, rarely affecting the carpus (<2% of hand GCTs), and is associated with recurrence rates up to 87%. Management of carpal GCT is challenging due to the limited bone volume, risk of damage to articular cartilage, and the need to preserve wrist function.

Case report: A 38-year-old male presented with recurrent GCT of his left wrist 1 year after curettage and bone grafting. He had painful swelling, restricted motion, and an expansile lesion involving the distal carpal row and bases of the 2nd-4th metacarpals. He underwent en bloc excision with extended curettage and reconstruction using iliac crest autograft stabilized by Kirschner wires. Post-operatively, he had good pain relief and maintained good wrist motion. At 12 months, positron emission tomography - computed tomography showed no recurrence or metastasis; Mayo Wrist Score was 85 (Good) and the disabilities of the arm, shoulder and hand score was 8.3.

Conclusion: Recurrent carpal GCTB can be managed with en bloc excision, extended curettage, autografting, and temporary fixation, achieving adequate disease control and preservation of wrist motion. Long-term surveillance remains essential as recurrence is high in lesions of the carpal bones.

骨巨细胞瘤(GCTB)是一种良性但局部侵袭性病变,很少影响腕骨(病例报告:一名38岁男性在刮除和植骨1年后出现左手腕GCT复发。他有疼痛肿胀,活动受限,扩张性病变累及远端腕排和第二至第四掌骨基部。他接受了整体切除和扩大刮除,并使用克氏针稳定的髂骨自体移植物重建。术后,患者疼痛缓解,手腕活动良好。12个月时,正电子发射断层扫描-计算机断层扫描未发现复发或转移;Mayo腕部评分为85分(良好),手臂、肩部和手部残疾评分为8.3分。结论:复发性腕GCTB可以通过整体切除、扩大刮除、自体移植和临时固定来治疗,达到充分的疾病控制和保持腕关节活动。由于腕骨病变的复发率很高,长期监测仍然是必要的。
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引用次数: 0
Retrieval of a Sunken Interference Screw during Core Decompression and Autologous Adult Live-cultured Osteoblast Injection for Bilateral Hip Avascular Necrosis: A Case Report. 椎体减压术中取出下凹干涉螺钉及自体成人活培养成骨细胞注射治疗双侧髋关节缺血性坏死1例报告。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6476
Alok C Agrawal, Harshal Sakale, Darshan Temker, Shubham Sakarkar

Introduction: Interference screws are commonly used implants, particularly in arthroscopic cruciate ligament reconstruction, where they achieve fixation by compression and friction rather than by threads. We report a case of a sunken interference screw, used as a stopper during core decompression and autologous adult live-cultured osteoblast (AALCO) injection for avascular necrosis (AVN) of the hip, which was successfully managed using a minimally invasive instrument-assisted retrieval technique.

Case report: A 67-year-old male with bilateral hip AVN underwent bilateral core decompression and AALCO injection. After track preparation and drilling of the necrotic areas in the femoral head with an 8 mm reamer, an 8 mm interference screw was inserted before injection of the AALCO. The screw migrated into the femoral neck and became sunken, complicating retrieval. Using a combination of standard orthopedic operating room instruments, i.e., without specialised instruments for retained implant removal, the screw was retrieved without additional morbidity. The AALCO was injected as planned, and the patient had an uneventful post-operative recovery.

Conclusion: A sunken interference screw in the proximal femur is a rare but challenging intraoperative complication. Our retrieval method using readily available instruments offers a safe and reproducible solution in such scenarios.

介绍:干涉螺钉是常用的植入物,特别是在关节镜下的十字韧带重建中,它们通过压缩和摩擦而不是螺纹来实现固定。我们报告了一例下沉式干涉螺钉,在髋关节缺血性坏死(AVN)的核心减压和自体成人活培养成骨细胞(AALCO)注射中用作塞钉,并成功地使用微创器械辅助检索技术进行治疗。病例报告:67岁男性双侧髋关节AVN行双侧核心减压和AALCO注射。用8mm铰刀对股骨头坏死区域进行径迹准备和钻孔后,插入8mm干涉螺钉,然后注射AALCO。螺钉移位至股骨颈内并凹陷,使取出更为复杂。使用标准的骨科手术室器械组合,即没有专门的器械来去除保留的种植体,螺钉被取出,没有额外的发病率。按计划注射AALCO,患者术后恢复顺利。结论:股骨近端凹陷干涉螺钉是一种罕见但具有挑战性的术中并发症。我们的检索方法使用现成的仪器,在这种情况下提供了一个安全和可重复的解决方案。
{"title":"Retrieval of a Sunken Interference Screw during Core Decompression and Autologous Adult Live-cultured Osteoblast Injection for Bilateral Hip Avascular Necrosis: A Case Report.","authors":"Alok C Agrawal, Harshal Sakale, Darshan Temker, Shubham Sakarkar","doi":"10.13107/jocr.2025.v15.i12.6476","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i12.6476","url":null,"abstract":"<p><strong>Introduction: </strong>Interference screws are commonly used implants, particularly in arthroscopic cruciate ligament reconstruction, where they achieve fixation by compression and friction rather than by threads. We report a case of a sunken interference screw, used as a stopper during core decompression and autologous adult live-cultured osteoblast (AALCO) injection for avascular necrosis (AVN) of the hip, which was successfully managed using a minimally invasive instrument-assisted retrieval technique.</p><p><strong>Case report: </strong>A 67-year-old male with bilateral hip AVN underwent bilateral core decompression and AALCO injection. After track preparation and drilling of the necrotic areas in the femoral head with an 8 mm reamer, an 8 mm interference screw was inserted before injection of the AALCO. The screw migrated into the femoral neck and became sunken, complicating retrieval. Using a combination of standard orthopedic operating room instruments, i.e., without specialised instruments for retained implant removal, the screw was retrieved without additional morbidity. The AALCO was injected as planned, and the patient had an uneventful post-operative recovery.</p><p><strong>Conclusion: </strong>A sunken interference screw in the proximal femur is a rare but challenging intraoperative complication. Our retrieval method using readily available instruments offers a safe and reproducible solution in such scenarios.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 12","pages":"125-128"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fixation of Distal Fibula Fractures Associated with Extra-articular Distal One-third Tibia Fractures - Is It Necessary? 腓骨远端骨折伴胫骨远端三分之一关节外骨折的固定-有必要吗?
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6574
Kishore Ragavendra Rajesh, Sundar Suriyakumar, J K Giriraj Harshavardhan, C Sitsabesan, M Tavfiq, S Aravind

Introduction: Fractures involving the distal third of both bone leg are one of the common long bone fractures with significant concern owing to the amount of soft-tissue damage incurred and poor prognosis with respect to fracture fixation.

Aim: The aim of the study is to evaluate whether fibula fixation is necessary along with internal fixation of extra-articular distal tibia fractures by comparing the clinico-radiological and functional outcome of patients of extra-articular distal third tibia fractures with fibula "fixed" and fibula "not fixed" group.

Materials and methods: A prospective cohort study with a sample size of 30 patients was conducted in Sri Ramachandra Institute of Higher Education and Research between March 2023 and May 2024. Fibula fixation was done in one group, and the fibula was not fixed in the control group. Research methodology includes radiological evaluation for coronal and sagittal plane malalignment, Radiographic Union Score for Tibial fractures (RUST) scoring, and clinically, rotational malalignment and presence of post-operative infection. All cases were followed up for a minimum duration of 6 months to assess union of tibia fractures in both groups.

Results: Tibial bone union rate was better in the fibula not fixed (control) group compared to the fibula fixed group (P = 0.032), confirmed by the RUST scoring (P = 0.047), which was statistically significant.

Conclusion: There was no significant improvement with additional fibula fixation in the healing of distal tibia fractures, but rather causes greater morbidity in terms of wound infections and delayed healing of the tibia. This clearly demonstrates that fibula fixation in extra-articular distal tibia fractures when the fracture does not affect the syndesmosis or ankle mortise is not necessary, and is associated with a higher risk of tibial non-union.

导言:两条腿骨远端三分之一的骨折是常见的长骨骨折之一,由于其造成的软组织损伤和骨折固定预后差,值得关注。目的:本研究的目的是通过比较腓骨“固定”组和腓骨“不固定”组胫骨远端关节外骨折患者的临床影像学和功能预后,评估腓骨内固定是否有必要同时进行胫骨远端关节外骨折内固定。材料与方法:2023年3月至2024年5月,在Sri Ramachandra高等教育研究所进行了一项前瞻性队列研究,样本量为30例患者。其中一组做腓骨固定,对照组不做腓骨固定。研究方法包括冠状面和矢状面排列错位的放射学评估,胫骨骨折放射联合评分(RUST)评分,以及临床,旋转排列错位和术后感染的存在。所有病例随访至少6个月,以评估两组胫骨骨折愈合情况。结果:经RUST评分(P = 0.047)证实,未固定腓骨组(对照组)胫骨骨愈合率优于固定腓骨组(P = 0.032),差异有统计学意义。结论:额外的腓骨固定对胫骨远端骨折的愈合没有明显的改善,但在伤口感染和胫骨延迟愈合方面会引起更高的发病率。这清楚地表明,当骨折不影响关节联合或踝关节时,胫骨远端关节外骨折的腓骨固定是不必要的,并且与胫骨不愈合的高风险相关。
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引用次数: 0
Trends in Rheumatoid Arthritis Mortality in the United States, 1999-2020. 1999-2020年美国类风湿关节炎死亡率趋势
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6548
Aamir Shahzad, Haji Bahar Ali, Muhammad Bilal, Hasnain Chohan, Annabelle Alexis Shaw, Muhammad Shehroze Waseem
<p><strong>Introduction: </strong>Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with systemic complications and increased mortality risk. Advances in RA treatment (early aggressive therapy, biologics) since the late 1990s have improved disease control and were expected to reduce mortality. We analyzed national trends in RA-related mortality from 1999 to 2020 to assess overall changes and disparities by sex, age, race/ethnicity, region, and urbanicity in the United States.</p><p><strong>Materials and methods: </strong>We conducted a retrospective time-trend analysis using the cause of death WONDER multiple-cause-of-death database. Deaths among U.S. residents aged ≥25 years with RA as the underlying cause (ICD-10 codes M05.x, M06.x, M08.0) from 1999 to 2020 were extracted. Age-adjusted mortality rates (AAMR) per 100,000 (2000 US standard population) were calculated overall and stratified by sex, age group, race/ethnicity, census region, and metropolitan versus nonmetropolitan residence. Joinpoint regression was used to evaluate changes in trends and estimate annual percent change (APC).</p><p><strong>Results: </strong>A total of 210,156 RA-related deaths occurred from 1999 to 2020. The AAMR declined from 5.65/100,000 in 1999 to a nadir of 3.33 in 2019 - an average annual decrease of about -2% to -3%, but then rose to 4.07 in 2020. Female patients had higher RA mortality than males throughout (2020 AAMR 5.31 vs. 2.51). Both sexes experienced significant mortality declines through 2018 (female APC -2.4%; male APC -3.0% overall), followed by a sharp increase in 2018-2020 (female APC +9.1%; male +6.3%). By age, the 65+ years group accounted for the vast majority of RA deaths and saw the largest absolute decline (AAPC -2.1%), whereas younger age groups had lower rates and smaller or no improvements. RA mortality fell across all major racial/ethnic groups except American Indians/Alaska Natives. In 2018, non-Hispanic White AAMR dropped to ~3.2, Black ~2.8, Hispanic ~2.7, and Asian/Pacific Islander ~1.8, while Native American rates remained high (~8+). A significant rebound in 2020 was observed, especially among Black and Hispanic populations. Regionally, the Midwest and West had the highest RA mortality and the Northeast the lowest, but all regions showed parallel downward trends through 2018 (each APC ~-2.6% to -2.9%) with an upward inflection in 2020. RA mortality in non-metropolitan (rural) areas was consistently higher than in metropolitan areas (e.g., 2020 AAMR 5.3 vs. 3.8), despite similar relative declines pre-2018 and increases in 2020 (rural APC +9.9% vs. urban +8.8% for 2018-2020).</p><p><strong>Conclusion: </strong>From 1999 to 2019, U.S. RA mortality rates significantly decreased, likely reflecting improved RA treatments and cardiovascular risk management. These gains, however, were not shared equally; Native Americans and rural residents had persistently higher mortality and less improvement. Alarmingly, RA mortality
类风湿关节炎(RA)是一种慢性炎症性疾病,与全身并发症和死亡风险增加有关。自20世纪90年代末以来,类风湿性关节炎治疗(早期积极治疗,生物制剂)的进展改善了疾病控制,并有望降低死亡率。我们分析了1999年至2020年ra相关死亡率的全国趋势,以评估美国性别、年龄、种族/民族、地区和城市化程度的总体变化和差异。材料和方法:我们使用WONDER多死因数据库进行回顾性时间趋势分析。以类风湿性关节炎为根本原因的美国≥25岁居民死亡(ICD-10代码M05)。x, M06。x, M08.0)。每10万人(2000年美国标准人口)的年龄调整死亡率(AAMR)进行了总体计算,并按性别、年龄组、种族/民族、人口普查地区以及大都市与非大都市居住地进行了分层。联合点回归用于评估趋势变化和估计年百分比变化(APC)。结果:1999 - 2020年共发生210,156例ra相关死亡。AAMR从1999年的5.65/10万下降到2019年的最低点3.33 /10万,平均每年下降约-2%至-3%,但随后在2020年上升至4.07。女性患者的RA死亡率高于男性(2020年AAMR为5.31比2.51)。2018年,男女死亡率均显著下降(女性APC -2.4%;男性APC总体-3.0%),随后在2018-2020年急剧上升(女性APC +9.1%;男性APC +6.3%)。按年龄划分,65岁以上年龄组占RA死亡人数的绝大多数,绝对下降幅度最大(AAPC -2.1%),而年轻年龄组的发病率较低,改善幅度较小或没有改善。除美洲印第安人/阿拉斯加原住民外,RA死亡率在所有主要种族/族裔群体中均有所下降。2018年,非西班牙裔白人的AAMR降至~3.2,黑人降至~2.8,西班牙裔降至~2.7,亚洲/太平洋岛民降至~1.8,而美洲原住民的AAMR仍然很高(~8+)。2020年出现了显著反弹,尤其是在黑人和西班牙裔人群中。从区域上看,中西部和西部RA死亡率最高,东北部最低,但所有地区在2018年呈平行下降趋势(APC均为-2.6%至-2.9%),2020年呈上升趋势。非大都市(农村)地区的RA死亡率始终高于大都市地区(例如,2020年AAMR为5.3比3.8),尽管2018年之前的相对下降和2020年的上升相似(2018-2020年农村APC +9.9%比城市APC +8.8%)。结论:从1999年到2019年,美国RA死亡率显著下降,可能反映了RA治疗和心血管风险管理的改善。然而,这些收益并不是平均分配的;美洲原住民和农村居民的死亡率持续较高,改善较少。令人震惊的是,2020年类风湿性关节炎死亡率上升,与COVID-19大流行同时发生,这可能对类风湿性关节炎患者造成了不成比例的影响。需要持续的努力来了解和解决最近的增加,并缩小RA结果中持续存在的人口差距。
{"title":"Trends in Rheumatoid Arthritis Mortality in the United States, 1999-2020.","authors":"Aamir Shahzad, Haji Bahar Ali, Muhammad Bilal, Hasnain Chohan, Annabelle Alexis Shaw, Muhammad Shehroze Waseem","doi":"10.13107/jocr.2025.v15.i12.6548","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i12.6548","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with systemic complications and increased mortality risk. Advances in RA treatment (early aggressive therapy, biologics) since the late 1990s have improved disease control and were expected to reduce mortality. We analyzed national trends in RA-related mortality from 1999 to 2020 to assess overall changes and disparities by sex, age, race/ethnicity, region, and urbanicity in the United States.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;We conducted a retrospective time-trend analysis using the cause of death WONDER multiple-cause-of-death database. Deaths among U.S. residents aged ≥25 years with RA as the underlying cause (ICD-10 codes M05.x, M06.x, M08.0) from 1999 to 2020 were extracted. Age-adjusted mortality rates (AAMR) per 100,000 (2000 US standard population) were calculated overall and stratified by sex, age group, race/ethnicity, census region, and metropolitan versus nonmetropolitan residence. Joinpoint regression was used to evaluate changes in trends and estimate annual percent change (APC).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 210,156 RA-related deaths occurred from 1999 to 2020. The AAMR declined from 5.65/100,000 in 1999 to a nadir of 3.33 in 2019 - an average annual decrease of about -2% to -3%, but then rose to 4.07 in 2020. Female patients had higher RA mortality than males throughout (2020 AAMR 5.31 vs. 2.51). Both sexes experienced significant mortality declines through 2018 (female APC -2.4%; male APC -3.0% overall), followed by a sharp increase in 2018-2020 (female APC +9.1%; male +6.3%). By age, the 65+ years group accounted for the vast majority of RA deaths and saw the largest absolute decline (AAPC -2.1%), whereas younger age groups had lower rates and smaller or no improvements. RA mortality fell across all major racial/ethnic groups except American Indians/Alaska Natives. In 2018, non-Hispanic White AAMR dropped to ~3.2, Black ~2.8, Hispanic ~2.7, and Asian/Pacific Islander ~1.8, while Native American rates remained high (~8+). A significant rebound in 2020 was observed, especially among Black and Hispanic populations. Regionally, the Midwest and West had the highest RA mortality and the Northeast the lowest, but all regions showed parallel downward trends through 2018 (each APC ~-2.6% to -2.9%) with an upward inflection in 2020. RA mortality in non-metropolitan (rural) areas was consistently higher than in metropolitan areas (e.g., 2020 AAMR 5.3 vs. 3.8), despite similar relative declines pre-2018 and increases in 2020 (rural APC +9.9% vs. urban +8.8% for 2018-2020).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;From 1999 to 2019, U.S. RA mortality rates significantly decreased, likely reflecting improved RA treatments and cardiovascular risk management. These gains, however, were not shared equally; Native Americans and rural residents had persistently higher mortality and less improvement. Alarmingly, RA mortality ","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 12","pages":"321-328"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Twist in the Shoulder Tale: Proximal Humerus Fracture Following Trapezius Transfer - A Case Report. 肩关节扭曲:斜方肌转移后肱骨近端骨折1例报告。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6458
Kumar Parth, Rajendra Phunde, Surendar Singh Bava, Maulik Kothari, Hunaid Haider, Rohit Somani

Introduction: Proximal humerus fractures constitute approximately 4-6% of all fractures, commonly affecting the elderly due to low-energy trauma and osteoporotic bones. Two-part surgical neck fractures are the most frequent subtype. In younger individuals, high-energy trauma is a usual cause. However, a proximal humerus fracture in a patient with a history of trapezius muscle transfer for brachial plexus injury is an extremely rare clinical scenario, with limited literature available on its management and rehabilitation.

Case report: A 30-year-old right-hand-dominant male presented with acute pain and swelling in the right upper arm following a non-traumatic event during aggressive physiotherapy. He had a history of brachial plexus injury managed by double Oberlin nerve transfer and later a trapezius transfer due to poor shoulder function. Two months into post-operative rehabilitation, he sustained a surgical neck humeral fracture. Open reduction and internal fixation with a dynamic compression plate and subpectoral biceps tenodesis were performed. A structured post-operative rehabilitation protocol resulted in a functional recovery with 90° of shoulder abduction at 1-year follow-up.

Conclusion: Peri-implant fractures following trapezius transfer are rare and demand careful surgical and rehabilitation planning. This case highlights the importance of cautious, supervised, and graded physiotherapy to prevent such complications and optimize outcomes.

简介:肱骨近端骨折约占所有骨折的4-6%,由于低能创伤和骨质疏松,通常影响老年人。两部分手术颈骨折是最常见的亚型。在年轻人中,高能创伤是常见的病因。然而,有臂丛损伤斜方肌转移病史的患者发生肱骨近端骨折是一种极为罕见的临床情况,有关其治疗和康复的文献有限。病例报告:一个30岁的男性右手优势提出急性疼痛和肿胀在右臂后非创伤性事件在积极的物理治疗。他有臂丛神经损伤史,由于肩部功能不佳,接受了双Oberlin神经转移和后斜方肌转移。术后康复两个月后,他颈部肱骨骨折。采用动态加压钢板和胸下二头肌肌腱固定术进行切开复位和内固定。结构化的术后康复方案在1年的随访中导致功能恢复,肩关节外展90°。结论:斜方肌移位后种植体周围骨折是罕见的,需要仔细的手术和康复计划。本病例强调了谨慎、监督和分级物理治疗的重要性,以防止此类并发症和优化结果。
{"title":"A Twist in the Shoulder Tale: Proximal Humerus Fracture Following Trapezius Transfer - A Case Report.","authors":"Kumar Parth, Rajendra Phunde, Surendar Singh Bava, Maulik Kothari, Hunaid Haider, Rohit Somani","doi":"10.13107/jocr.2025.v15.i12.6458","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i12.6458","url":null,"abstract":"<p><strong>Introduction: </strong>Proximal humerus fractures constitute approximately 4-6% of all fractures, commonly affecting the elderly due to low-energy trauma and osteoporotic bones. Two-part surgical neck fractures are the most frequent subtype. In younger individuals, high-energy trauma is a usual cause. However, a proximal humerus fracture in a patient with a history of trapezius muscle transfer for brachial plexus injury is an extremely rare clinical scenario, with limited literature available on its management and rehabilitation.</p><p><strong>Case report: </strong>A 30-year-old right-hand-dominant male presented with acute pain and swelling in the right upper arm following a non-traumatic event during aggressive physiotherapy. He had a history of brachial plexus injury managed by double Oberlin nerve transfer and later a trapezius transfer due to poor shoulder function. Two months into post-operative rehabilitation, he sustained a surgical neck humeral fracture. Open reduction and internal fixation with a dynamic compression plate and subpectoral biceps tenodesis were performed. A structured post-operative rehabilitation protocol resulted in a functional recovery with 90° of shoulder abduction at 1-year follow-up.</p><p><strong>Conclusion: </strong>Peri-implant fractures following trapezius transfer are rare and demand careful surgical and rehabilitation planning. This case highlights the importance of cautious, supervised, and graded physiotherapy to prevent such complications and optimize outcomes.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 12","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Botulinum Toxin in Pre-pubic Aponeurotic Complex Injuries: A Case Series. 肉毒杆菌毒素治疗耻骨前腱膜复合损伤:一个病例系列。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6572
Andrea Bisciotti, Gian Nicola Bisciotti, Alessio Auci, Alessandro Bisciotti, Gabriella Cassaghi, Federica Parra Maria

Introduction: Injuries of the pre-pubic aponeurotic complex (PPAC) are a significant cause of groin pain syndrome. These injuries tend to have limited self-healing capacity because the injured area is kept apart by opposing forces exerted by the rectus abdominis (RA) and adductor longus muscles. Recently, botulinum toxin type A (BTX-A) has been successfully used in a case report describing a patient with PPAC injuries. This study aims to evaluate the efficacy of BTX-A in a series of patients with PPAC injuries.

Materials and methods: Ten male athletic subjects with PPAC injuries underwent infiltrative therapy with BTX-A at the level of the RA and adductor longus, followed by an 8-week rehabilitation program.

Results: Ultrasound assessment performed after the rehabilitation program showed that 9 subjects (90%) achieved complete restitutio ad integrum of the PPAC injury area, while 1 subject (10%) exhibited partial repair. At 12 months of follow-up, 9 patients (90%) returned to sports activity, 8 (80%) at the same level, and 1 (10%) at a lower level, but not due to residual pain. No adverse effects were recorded.

Conclusion: BTX-A infiltrative therapy appears to be a safe, effective, and promising treatment for PPAC injuries, enabling a quick return to sporting activity.

前言:耻骨前腱膜复合体(PPAC)损伤是腹股沟疼痛综合征的一个重要原因。这些损伤往往具有有限的自我修复能力,因为受伤区域被腹直肌(RA)和长内收肌施加的相反力量分开。最近,A型肉毒毒素(BTX-A)已成功地用于一个病例报告,描述了一个病人的PPAC损伤。本研究旨在评价BTX-A在一系列PPAC损伤患者中的疗效。材料与方法:10例男性运动性PPAC损伤患者在RA和长内收肌水平应用BTX-A浸润治疗,随后进行8周的康复计划。结果:康复方案后超声检查显示9例(90%)患者PPAC损伤区完全恢复完整,1例(10%)患者部分修复。在12个月的随访中,9名患者(90%)恢复了体育活动,8名患者(80%)恢复了相同水平,1名患者(10%)恢复了较低水平,但不是由于残余疼痛。无不良反应记录。结论:BTX-A浸润治疗是一种安全、有效、有希望的治疗PPAC损伤的方法,可使患者快速恢复运动。
{"title":"The Use of Botulinum Toxin in Pre-pubic Aponeurotic Complex Injuries: A Case Series.","authors":"Andrea Bisciotti, Gian Nicola Bisciotti, Alessio Auci, Alessandro Bisciotti, Gabriella Cassaghi, Federica Parra Maria","doi":"10.13107/jocr.2025.v15.i12.6572","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i12.6572","url":null,"abstract":"<p><strong>Introduction: </strong>Injuries of the pre-pubic aponeurotic complex (PPAC) are a significant cause of groin pain syndrome. These injuries tend to have limited self-healing capacity because the injured area is kept apart by opposing forces exerted by the rectus abdominis (RA) and adductor longus muscles. Recently, botulinum toxin type A (BTX-A) has been successfully used in a case report describing a patient with PPAC injuries. This study aims to evaluate the efficacy of BTX-A in a series of patients with PPAC injuries.</p><p><strong>Materials and methods: </strong>Ten male athletic subjects with PPAC injuries underwent infiltrative therapy with BTX-A at the level of the RA and adductor longus, followed by an 8-week rehabilitation program.</p><p><strong>Results: </strong>Ultrasound assessment performed after the rehabilitation program showed that 9 subjects (90%) achieved complete restitutio ad integrum of the PPAC injury area, while 1 subject (10%) exhibited partial repair. At 12 months of follow-up, 9 patients (90%) returned to sports activity, 8 (80%) at the same level, and 1 (10%) at a lower level, but not due to residual pain. No adverse effects were recorded.</p><p><strong>Conclusion: </strong>BTX-A infiltrative therapy appears to be a safe, effective, and promising treatment for PPAC injuries, enabling a quick return to sporting activity.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 12","pages":"398-405"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Outcome of Intra-articular Platelet-Rich Plasma in the Treatment of Frozen Shoulder. 关节内富血小板血浆治疗肩周炎的功能结局。
Pub Date : 2025-12-01 DOI: 10.13107/jocr.2025.v15.i12.6566
Gautham Saravanan, Prabhakaran Anbalagan, Ashok Ramanujam, Umar Farook

Introduction: Frozen shoulder, also known as adhesive capsulitis, is a condition marked by persistent shoulder pain and limited range of motion. Platelet-rich plasma (PRP) has recently gained attention as a biologically active therapy capable of enhancing tissue repair and regeneration.

Objective: This study aimed to assess the impact of intra-articular PRP injections on functional recovery in individuals with frozen shoulder.

Materials and methods: A prospective interventional study was performed involving 30 patients who had not responded to standard conservative therapies. Each participant received a single PRP injection and was monitored at intervals of 1 week, 1 month, 3 months, and 6 months. Pain and functional outcomes were measured using the visual analog scale (VAS) and disabilities of the arm, shoulder, and hand (DASH) scores. Subgroup analyses examined the effects of age, diabetes status, and duration of symptoms.

Findings: After 6 months, there was a 75.3% reduction in pain scores and a 72.1% improvement in functional scores. Patients who were younger, non-diabetic, or had symptoms for <6 months experienced more favorable outcomes. Multivariate analysis confirmed age, diabetes, and symptom duration as significant outcome predictors.

Conclusion: Intra-articular PRP injections appear to significantly reduce pain and enhance function in patients with frozen shoulder, with the most pronounced benefits observed in early-stage, younger, non-diabetic individuals. Despite certain study limitations, these results highlight PRP's potential as an effective treatment alternative.

简介:肩周炎,也被称为粘连性肩膜炎,是一种以持续肩关节疼痛和活动范围受限为特征的疾病。富血小板血浆(PRP)作为一种能够促进组织修复和再生的生物活性疗法,最近受到了人们的关注。目的:本研究旨在评估关节内PRP注射对肩周炎患者功能恢复的影响。材料和方法:对30例标准保守治疗无效的患者进行前瞻性介入研究。每位参与者接受单次PRP注射,并在1周、1个月、3个月和6个月的间隔进行监测。疼痛和功能结果采用视觉模拟量表(VAS)和手臂、肩膀和手的残疾(DASH)评分进行测量。亚组分析考察了年龄、糖尿病状况和症状持续时间的影响。结果:6个月后,疼痛评分降低了75.3%,功能评分提高了72.1%。结论:关节内PRP注射似乎可以显著减轻肩周炎患者的疼痛和增强功能,在早期、年轻、非糖尿病患者中观察到最明显的益处。尽管有一定的研究局限性,但这些结果突出了PRP作为有效治疗方案的潜力。
{"title":"Functional Outcome of Intra-articular Platelet-Rich Plasma in the Treatment of Frozen Shoulder.","authors":"Gautham Saravanan, Prabhakaran Anbalagan, Ashok Ramanujam, Umar Farook","doi":"10.13107/jocr.2025.v15.i12.6566","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i12.6566","url":null,"abstract":"<p><strong>Introduction: </strong>Frozen shoulder, also known as adhesive capsulitis, is a condition marked by persistent shoulder pain and limited range of motion. Platelet-rich plasma (PRP) has recently gained attention as a biologically active therapy capable of enhancing tissue repair and regeneration.</p><p><strong>Objective: </strong>This study aimed to assess the impact of intra-articular PRP injections on functional recovery in individuals with frozen shoulder.</p><p><strong>Materials and methods: </strong>A prospective interventional study was performed involving 30 patients who had not responded to standard conservative therapies. Each participant received a single PRP injection and was monitored at intervals of 1 week, 1 month, 3 months, and 6 months. Pain and functional outcomes were measured using the visual analog scale (VAS) and disabilities of the arm, shoulder, and hand (DASH) scores. Subgroup analyses examined the effects of age, diabetes status, and duration of symptoms.</p><p><strong>Findings: </strong>After 6 months, there was a 75.3% reduction in pain scores and a 72.1% improvement in functional scores. Patients who were younger, non-diabetic, or had symptoms for <6 months experienced more favorable outcomes. Multivariate analysis confirmed age, diabetes, and symptom duration as significant outcome predictors.</p><p><strong>Conclusion: </strong>Intra-articular PRP injections appear to significantly reduce pain and enhance function in patients with frozen shoulder, with the most pronounced benefits observed in early-stage, younger, non-diabetic individuals. Despite certain study limitations, these results highlight PRP's potential as an effective treatment alternative.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 12","pages":"379-385"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Orthopaedic Case Reports
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