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Cytokine levels in immediate loaded and unloaded mini-screw: A split-mouth randomised clinical trial. 细胞因子水平在立即加载和卸载微型螺钉:一项裂口随机临床试验。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-08-25 DOI: 10.1177/14653125251358815
Mariah Carboni Mendes, Gabriela Leite Pedroso, Paôla Caroline da Silva Mira, Amanda Cunha Regal Castro, Caio Luiz Bitencourt Reis, Maria Bernadete Sasso Stuani

Objective: To compare the levels of interleukin (IL)-1 beta (IL-1β), alpha (IL-1α), receptor antagonist (IL-1Ra), IL-10 and IL-13 in peri-mini-screw crevicular fluid (PMCF) between unloaded and immediately loaded mini-screws during orthodontic treatment.

Design: Single-centre paired split-mouth controlled trial.

Participants: Patients who required at least two mini-screws as a part of their orthodontic treatment at orthodontic clinic of School of Dentistry of Ribeirão Preto, University of São Paulo (USP) were recruited.

Methods: A total of 40 mini-screws were inserted into the interradicular alveolar bone in 16 patients. Using the coin toss method, each mini-screw was randomly allocated into one of two groups: a control group of unloaded (n = 20) and a group of immediately loaded mini-screws (n = 20). Immediately postoperatively, a continuous load in the range of 150-200 cN was applied to the mini-screws allocated to the loaded group. The PMCF was collected in four experimental times: immediately postoperatively (and on load time, to mini-screws allocated into the loaded group) and 7, 14 and 21 days postoperatively. Biomarker levels were measured using Multiplex Microsphere Immunoassays and compared between groups and covariates using statistical tests that accounted for multiple observations per participant (alpha =5%).

Results: No mini-screws were lost. There was a progressive and statistically significant increase of the biomarker's levels in the two groups during the experimental times (P <0.001). The biomarker levels were significantly higher in the immediately loaded group compared to the unloaded group at all time points (P <0.05), except for IL-10 after 7 days postoperatively.

Conclusion: Although all biomarker levels were statistically higher in the immediately loaded group at all experimental time points in comparison with the unloaded group, no mini-screws were lost. This suggests a balanced and normal adaptive bone response to the mechanical stress of immediate loading, with no negative impact on clinical outcomes.

目的:比较正畸治疗中未加载与即刻加载微型螺钉前后微型螺钉周围沟液(PMCF)中白细胞介素(IL)-1 β (IL-1β)、α (IL-1α)、受体拮抗剂(IL- 1ra)、IL-10和IL-13的水平。设计:单中心配对裂口对照试验。参与者:在巴西圣保罗大学(USP) ribebe o Preto牙科学院正畸诊所接受正畸治疗的患者,至少需要两个微型螺钉。方法:对16例患者进行根间牙槽骨内固定微型螺钉40枚。采用抛硬币的方法,将每个微型螺钉随机分为两组:未加载的对照组(n = 20)和立即加载的微型螺钉组(n = 20)。术后立即对分配给加载组的微型螺钉施加150-200 cN的连续负荷。PMCF在四个实验时间收集:术后立即(和加载时间,分配到加载组的微型螺钉)和术后7、14和21天。使用多重微球免疫测定法测量生物标志物水平,并使用统计检验在组间和协变量之间进行比较,统计检验占每个参与者的多个观察值(α =5%)。结果:无微型螺钉丢失。两组在实验时间内的生物标志物水平均有进进性和统计学意义上的升高(P P结论:尽管在所有实验时间点,立即加载组的生物标志物水平均高于未加载组,但没有微型螺钉丢失。这表明对即刻负荷的机械应力有平衡和正常的适应性骨反应,对临床结果没有负面影响。
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引用次数: 0
Continued Professional Development. 持续专业发展。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1177/14653125251374455
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引用次数: 0
Meet the Author. 认识作者。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1177/14653125251374445
Sarah Hisham Abu Arqub
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引用次数: 0
Editorial. 社论。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1177/14653125251374432
Jayne Harrison
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引用次数: 0
The Spacing Index (TSI): A diagnostic classification for spaced dentitions. 间距指数(TSI):间距牙列的诊断分类。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-08-09 DOI: 10.1177/14653125251358833
Minnie Lyons-Coleman, Claire Bates, Nicky Mandall, Paul Bassett

Objective: To test the validity and reliability of The Spacing Index (TSI).

Design: A single-centre diagnostic study.

Setting: Orthodontic Department, Tameside and Glossop Integrated Care NHS Foundation Trust, Manchester, UKMethods:TSI was outlined based on the principle of mild spacing (0-4 mm), moderate spacing (5-8 mm) and severe spacing (>8 mm). A total of 53 anonymised study models were selected as a convenience sample of patients attending hypodontia multidisciplinary clinics. A range of cases with different amounts of spacing in each arch was chosen. Each model was measured by ML-C in millimetres using calibrated Vernier callipers and then subdivided to give the gold standard spacing TSI categorisation of mild, moderate or severe. Two test raters (CB and NM) then visually assessed the same study models and rated the spacing as mild, moderate or severe. Comparison of the gold standard rating and the test rating was made to assess the validity of TSI. The reliability of the index was assessed by both the gold standard and test raters 2 weeks later.

Results: The weighted kappa score was 0.79 (substantial agreement) between the gold standard rater and the test raters for the mild, moderate and severe TSI categories. The weighted kappa scores were greater than 0.80, demonstrating almost perfect intra-observer reliability over time.

Conclusion: The proposed TSI has been shown to be valid and reliable and could be used to categorise spacing during routine orthodontic assessment.

目的:检验间隔指数(TSI)的效度和信度。设计:单中心诊断研究。环境:正畸科,Tameside和Glossop综合护理NHS基金会信托,曼彻斯特,英国方法:TSI根据轻度间距(0- 4mm),中度间距(5- 8mm)和重度间距(> - 8mm)的原则进行概述。总共选择53个匿名研究模型作为就诊于下颌缺损多学科诊所的患者的方便样本。选择了一系列在每个拱门中具有不同间距的案例。每个模型都是用ML-C测量的,以毫米为单位,使用校准的游标卡尺,然后再细分,给出轻度、中度或重度的黄金标准间距TSI分类。然后,两名测试评分者(CB和NM)对相同的研究模型进行视觉评估,并将间距评为轻度、中度或重度。通过金标准评定与试验评定的比较,评价TSI的有效性。2周后,由金标准和测试评分者对该指数的可靠性进行评估。结果:金标准评分者与测试评分者对轻度、中度和重度TSI类别的加权kappa评分为0.79(基本一致)。加权kappa分数大于0.80,随着时间的推移,显示出几乎完美的观察者内部可靠性。结论:所提出的TSI是有效可靠的,可用于常规正畸评估中间距的分类。
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引用次数: 0
Power arms as adjuncts for root control in lower incisor extraction treatment with clear aligners: A case report. 动力臂作为辅助工具用于下门牙拔牙治疗中根的控制:一例报告。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-08-17 DOI: 10.1177/14653125251358825
Bayan Alyammahi, Abrar Mohammad, Kabir Syed Gyasudeen, Yasmin Youssef, Tommaso Castroflorio, Mauro Farella, Sabarinath Prasad

Background: Clear aligner therapy (CAT) has become a popular choice among patients seeking orthodontic treatment. However, CAT is not optimal for certain types of tooth movements. This case report illustrates a hybrid approach combining CAT with power arms to achieve controlled space closure after lower incisor extraction.

Case presentation: A fit and healthy man presented with a Class 1 malocclusion on a Class 1 skeletal base with bimaxillary protrusion, slightly increased vertical proportions, and mild crowding in the upper and lower arches. He was concerned about his 'irregular lower front teeth and inability to clean them'.

Intervention: Lower incisor extraction treated with clear aligner therapy (CAT).

Results: The patient's malocclusion was successfully treated with CAT and the extraction of a lower incisor, achieving satisfactory root parallelism for the teeth adjacent to the extraction space. The patient reported satisfaction with the treatment results.

Conclusion: Power arms can be considered a useful adjunct to CAT for minimising unwanted tipping in lower incisor extraction cases. Further research on more complex cases and a larger sample size is warranted to validate the findings of this case report and explore long-term stability.

背景:在寻求正畸治疗的患者中,透明矫正器治疗(CAT)已成为一种流行的选择。然而,CAT并不适合某些类型的牙齿运动。本病例报告阐述了一种结合CAT和动力臂的混合入路,在下门牙拔除后实现可控的空间关闭。病例介绍:一名健康的男性,在1级骨基上出现1级错颌,双颌突出,垂直比例轻微增加,上下弓轻度拥挤。他担心自己的“下门牙不整齐,而且无法清洁”。干预:下门牙拔牙采用清除矫正器治疗。结果:该患者的错牙合经CAT和下切牙拔牙治疗成功,拔牙间隙附近的牙根平行度较好。病人对治疗结果表示满意。结论:在下门牙拔牙时,动力臂可以被认为是一种有用的辅助工具,可以最大限度地减少不必要的倾斜。需要对更复杂的病例和更大的样本量进行进一步研究,以验证本病例报告的发现并探索其长期稳定性。
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引用次数: 0
Remote appointments in orthodontics and oral and maxillofacial surgery: Part 2 clinician perceptions. 正畸和口腔颌面外科的远程预约:第2部分临床医生的看法。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2024-12-20 DOI: 10.1177/14653125241301450
Gurdeep Kaur Hans, Nigel Peter Hunt, Helen Travess

Objectives: To assess clinician perceptions of and satisfaction with remote appointments in orthodontics and oral and maxillofacial surgery (OMFS).

Design: Cross-sectional questionnaire-based study.

Setting: Orthodontic and OMFS departments in six acute NHS hospital Trusts in the UK.

Participants: A total of 36 (a mixture of consultants, specialty doctors, registrars and therapists in both orthodontics and OMFS) completed responses were received.

Method: Once piloted, questionnaires were disseminated across six hospital Trusts to orthodontic and OMFS clinicians. A combination of face-to-face (F2F) and online dissemination was used.

Results: A total of 28 of 36 (77.8%) questionnaires were completed, 75% (n = 21) by orthodontic clinicians and 25% (n = 7) by OMFS clinicians. A 100% (n = 21) response rate was achieved for orthodontic clinicians, compared to a 47% (n = 7/15) response rate for OMFS clinicians. High levels of clinician satisfaction were found for clinician confidentiality; however, concerns remained around patient confidentiality and the inability to conduct a clinical examination. The majority (n = 21, 75%) of clinicians felt that remote appointments had their place in the post-pandemic era, particularly for retainer reviews in orthodontics and biopsy results in OMFS.

Conclusion: When appropriately triaged, the majority of remote appointments do save a face-to-face visit, and there is a place for remote platforms in both specialties going forward. However further research is required in the post-pandemic era to ascertain the full long-term applicability of remote orthodontic and OMFS consultations.

目的:评估临床医生对正畸和口腔颌面外科(OMFS)远程预约的看法和满意度。设计:横断面问卷研究。环境:正畸和OMFS部门在六个急性NHS医院信托在英国。参与者:共收到36份(包括正畸和OMFS的顾问、专科医生、登记员和治疗师)完成的回复。方法:一旦试点,问卷在六个医院信托分发到正畸和OMFS临床医生。采用面对面(F2F)和在线传播相结合的方式。结果:36份问卷共完成28份(77.8%),其中75% (n = 21)由正畸临床医生完成,25% (n = 7)由OMFS临床医生完成。正畸临床医生的有效率为100% (n = 21),而OMFS临床医生的有效率为47% (n = 7/15)。临床医生对保密工作的满意度较高;然而,对患者保密和无法进行临床检查的担忧仍然存在。大多数临床医生(n = 21.75%)认为远程预约在大流行后时代有其地位,特别是对于正畸的固位器检查和OMFS的活检结果。结论:如果经过适当的分类,大多数远程预约确实节省了面对面的就诊,并且远程平台在这两个专业中都有一席之地。然而,在大流行后时代,需要进一步研究,以确定远程正畸和OMFS咨询的全面长期适用性。
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引用次数: 0
Meet the Author. 认识作者。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1177/14653125251345289
Minnie Lyons-Coleman
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引用次数: 0
Corrigendum to: Vertical and sagittal changes produced by an expander with differential opening versus a fan-type expander: A post-hoc analysis of a randomised controlled trial. 差动开口扩张器与扇形扩张器产生的垂直和矢状改变:一项随机对照试验的事后分析。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1177/14653125241306698
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引用次数: 0
A novel appliance for Class II dentoalveolar correction. 一种用于II类牙槽矫正的新型矫治器。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-01-15 DOI: 10.1177/14653125241305149
Gilad Har-Zion

In recent years, a segmental approach to Class II correction has gained popularity among orthodontists. This concept is best represented by the Carrière Motion 3D™ Class II Appliance (CMA), which is an efficient and effective appliance for the treatment of Class II malocclusions. Although it is original and innovative, it also has some inherent flaws that can potentially interfere with its daily use. A segmental approach is described, based on a section of 0.016 × 0.022-inch stainless steel archwire connected to a molar band distally and to a bracket on the mesial side. This simple alternative presents a 'do-it-yourself' and an easy-to-construct mechanism that employs the same principles and identical mechanics to achieve Class II correction yet overcomes most of the disadvantages of other modalities. In our clinic, we found that this optional, useful sectional appliance can correct Class II malocclusion effectively, predictively and on a regular basis.

近年来,二级矫正的分段方法在正畸医师中越来越受欢迎。carriires Motion 3D™II类矫治器(CMA)是这一概念的最佳代表,它是一种治疗II类错颌的高效矫治器。虽然它是原创和创新的,但它也有一些内在的缺陷,可能会干扰它的日常使用。本文描述了一种分段方法,该方法是基于一段0.016 × 0.022英寸的不锈钢拱丝,其远端连接到磨牙带,中端连接到托架。这种简单的替代方案提供了一种“自己动手”和易于构建的机制,采用相同的原理和相同的机制来实现II级矫正,同时克服了其他模式的大多数缺点。在我们的临床中,我们发现这种可选的、有用的局部矫治器可以有效地、预测性地、定期地纠正II类错牙合。
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引用次数: 0
期刊
Journal of Orthodontics
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