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Vale Amy McRae 好吧,艾米·麦克雷
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-08-29 DOI: 10.1002/jppr.1879
Michael J. Dooley BPharm, GradDipHospPharm, PhD, FSHP, AdvPracPharm

This issue of the Journal includes a paper titled ‘Time for change: Improving neuromuscular blocking agent safety in Australia’.1 The lead author, Amy McRae, sadly passed away last year on 15 December, at home peacefully with her family by her side.

Amy had a passion and determination to improve the safe use of medicines and this influenced the many pharmacists, nurses, doctors, and patients who had the pleasure of interacting with her during her career. This included in her early role as a clinical pharmacist, through to more recently as Senior Medication Safety Pharmacist at Alfred Health. In addition, Amy was also the Senior Pharmacist, Quality Use of Medicines, Western Health and Senior Lecturer, Post-Graduate Studies and Professional Development Unit, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University.

Her contribution to improving the care of patients and reducing the risks associated with medication will be one of her many legacies. Amy was central in Australia-wide improvements to reduce neuromuscular blocking agent (NMBA) administration errors, which can cause unintended paralysis, respiratory arrest, severe permanent harm, and death. These endeavours included the publication of a national report Time for change: proposed improvements to the labelling and packaging of neuromuscular blocking agents in Australia.2 This work, supported by the Victorian Therapeutics Advisory Group and many other national organisations, resulted in the introduction of mandatory warning statements for the labels of NMBAs in Australia. Amy was also pivotal in a range of other initiatives, including reducing potentially fatal errors associated with high doses of insulin, the introduction of Tall Man lettering to reduce medication selection errors, and patient education and empowerment strategies to improve prophylaxis for venous thromboembolism.

We are very saddened that Amy is not here to share in this milestone but know that her impact and legacy will continue. Amy was a wonderful person whose courage and determination to live a full life was inspirational to many of us who knew her. Amy will continue to be missed by many and her impact on making care safer will be felt far into the future.

The author complies with the Journal's authorship policy.

Michael Dooley is the Editor-in-Chief of the Journal of Pharmacy Practice and Research.

Ethics approval was not required for this announcement.

本期《华尔街日报》刊登了一篇题为《是时候改变了:提高澳大利亚神经肌肉阻滞剂的安全性》的论文主要作者艾米·麦克雷于去年12月15日在家中与家人平静地离世。艾米对提高药物安全使用的热情和决心,影响了许多药剂师、护士、医生和在她的职业生涯中有幸与她互动的病人。这包括她早期作为临床药剂师的角色,直到最近作为阿尔弗雷德健康的高级药物安全药剂师。此外,Amy还是莫纳什大学药学和药物科学学院研究生学习和专业发展部门的高级药剂师、西方健康高级药剂师和高级讲师。她对改善患者护理和减少药物相关风险的贡献将成为她的众多遗产之一。Amy是澳大利亚范围内减少神经肌肉阻滞剂(NMBA)给药错误的核心,NMBA可能导致意外瘫痪、呼吸停止、严重的永久性伤害和死亡。这些努力包括一份国家报告的出版:改变的时间:建议改进澳大利亚神经肌肉阻滞剂的标签和包装。这项工作得到了维多利亚治疗咨询小组和许多其他国家组织的支持,导致澳大利亚引入了NMBAs标签的强制性警告声明。Amy在一系列其他倡议中也发挥了关键作用,包括减少与高剂量胰岛素相关的潜在致命错误,引入Tall Man字母以减少药物选择错误,以及患者教育和授权策略以改善静脉血栓栓塞的预防。我们很遗憾艾米不能在这里分享这一里程碑,但我们知道她的影响和遗产将继续下去。艾米是一个很棒的人,她过充实生活的勇气和决心鼓舞了我们许多认识她的人。许多人将继续怀念艾米,她在使护理更安全方面的影响将在遥远的未来被感受到。作者遵守《华尔街日报》的署名政策。迈克尔·杜利(Michael Dooley)是《药学实践与研究》杂志的主编。这项声明不需要伦理审批。
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引用次数: 0
Testing a medicine information needs identification tool (MINI-Q) with hospital inpatients in New Zealand 在新西兰的医院住院患者中测试药物信息需求识别工具(MINI‐Q)
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-08-25 DOI: 10.1002/jppr.1877
Trudi Aspden BPharm(Hons), PhD, Michelle Honey RN, PhD, Sarah Sneyd BA, BHSc, MPH, Kim Brackley DipPharm(Dist), PGDipHighE, MScClinPharm, Alana Cavadino BSc, MSc, PhD, Rosalie Chang BPharm, PGCert, Amy HY Chan BPharm(Hons), PhD

Background

Determining an individual's medicines information preferences and needs could enable health professionals to deliver more effective medicines information and help build patients' health literacy and ability to self-manage their health.

Aim

This descriptive, cross-sectional study aimed to test a new information needs assessment tool, the Medicine Information Needs for Individuals – Questionnaire (MINI-Q), which elicits what individuals want to know about their medicines. This study aimed to explore the face validity, acceptability, and feasibility of using the tool in a hospital inpatient setting.

Method

Ethical approval was obtained from Health and Disability Ethics Committees (Reference no: 18/NTA/137). Following ethical approval, adult hospital inpatients from two service divisions in one large urban hospital in New Zealand were invited to self-assess their medicines information needs using the 23-item MINI-Q via a tablet or on paper. Descriptive statistics were generated from the quantitative data and responses to a free-text question were inductively analysed.

Results

The MINI-Q was completed by 228 inpatients, 137 (60%) of whom used a tablet. Participants requested information on 80.6% of the possible topics. The most common topic that participants wanted information about was possible side effects (92%). No additional topics to include in the MINI-Q were identified from the free-text responses. The median completion time of the tablet version was 9.2 min (interquartile range 6.7–14.6).

Conclusion

The MINI-Q shows promise to efficiently identify an individual's medicines information needs in an inpatient setting. The findings reinforce that most people want to know all the basic information about their medicines, with side effects being particularly important.

确定个人的药物信息偏好和需求可以使卫生专业人员提供更有效的药物信息,并帮助培养患者的健康素养和自我管理健康的能力。这项描述性的横断面研究旨在测试一种新的信息需求评估工具,即个人药物信息需求问卷(MINI‐Q),该工具可以引出个人想要了解的药物信息。本研究旨在探讨在医院住院环境中使用该工具的面部有效性、可接受性和可行性。获得了健康和残疾伦理委员会的伦理批准(参考号:18/NTA/137)。在获得伦理批准后,来自新西兰一家大型城市医院两个服务部门的成年住院患者被邀请通过平板电脑或纸上使用23项MINI‐Q自我评估他们的药物信息需求。从定量数据中生成描述性统计数据,并对自由文本问题的回答进行归纳分析。MINI‐Q由228名住院患者完成,其中137人(60%)使用平板电脑。与会者要求提供80.6%的可能主题的信息。参与者想要了解的最常见的话题是可能的副作用(92%)。从自由文本回复中没有发现需要纳入MINI‐Q的其他主题。平板电脑版本的中位完成时间为9.2 min(四分位间距6.7-14.6)。MINI‐Q有望在住院环境中有效识别个人的药物信息需求。研究结果进一步表明,大多数人都想了解他们药物的所有基本信息,其中副作用尤为重要。
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引用次数: 0
Elective surgery cancellations due to suboptimal medicine management: a retrospective single site study 由于药物管理不理想而取消择期手术:一项回顾性单点研究
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-08-21 DOI: 10.1002/jppr.1876
Kate Elizabeth Doreen Ziser BPharm, GradDdpEd APP[II], MClinPharm, Jessica Barbara King BPharm, Natasha Alkass BPharm, Jane Elizabeth Dunsdon BPharm, BNursing APP[II]

Background

Elective surgery cancellations and delays are associated with negative financial and staffing ramifications, adverse clinical outcomes, and poor patient outcomes. The Princess Alexandra Hospital in Brisbane, Australia, performs approximately 15 000 elective surgeries per year and medication optimisation is pivotal in preparing a patient for surgery to avoid same day of surgery theatre cancellations. Ideally, patients are seen in a multidisciplinary pre-admission clinic for optimisation of their health and medicines, and to provide education regarding their surgery.

Aim

To calculate the incidence of elective surgery cancellations due to medication misadventure over a 12-month period.

Method

A retrospective audit at a tertiary Queensland Hospital was conducted over a 12-month period (April 2021–March 2022), including patients who had their elective surgeries cancelled. The medical records from the hospital's digital databases for patients who were identified by the hospital coding service as ‘unfit for surgery’ were screened to see if the reason for the surgery cancellation was due to medication misadventure. The project was reviewed by the Metro South Human Research Ethics Committee and deemed exempt from further review (Ref No: CM20221651).

Results

The surgery cancellation rate was 50% (n = 6626 cancelled surgeries from 13 255 total surgeries booked). The same day of surgery cancellation rate was 5.5% (n = 734). Medication misadventure resulting from suboptimal medicine management was responsible for 1% (n = 66 out of 6626 surgery cancellations). A total of 41% (n = 27) of patients had their surgery cancelled ahead of time by the pharmacist due to a medication not being withheld for long enough, which prevented a same-day cancellation.

Conclusion

Having a pre-admission clinic pharmacist improves preoperative medication optimisation and has been proven to avoid same-day cancellations.

选择性手术的取消和延误与负面的财务和人员影响、不良的临床结果和不良的患者结果有关。澳大利亚布里斯班的亚历山德拉公主医院演出约15场 000例择期手术,药物优化对于为患者做好手术准备以避免手术当天取消至关重要。理想情况下,患者可以在多学科的入院前诊所就诊,以优化他们的健康和药物,并提供有关他们手术的教育。计算12个月内因药物意外事故而取消择期手术的发生率。昆士兰一家三级医院进行了为期12个月(2021年4月至2022年3月)的回顾性审计,包括取消择期手术的患者。对医院数字数据库中被医院编码服务部门认定为“不适合手术”的患者的医疗记录进行了筛查,以确定取消手术的原因是否是药物意外。该项目由Metro South人类研究伦理委员会审查,并被视为免于进一步审查(参考号:CM20221651)。手术取消率为50%(n = 6626例手术从13例取消 总共预约了255个手术)。当天手术取消率为5.5%(n = 734)。不良药物管理导致的药物意外事故占1%(n = 6626例手术取消中有66例)。总共41%(n = 27)的患者由于药物扣留时间不够长而被药剂师提前取消了手术,这阻止了当天的取消。有一位入院前的诊所药剂师可以改善术前的药物优化,并已被证明可以避免当天取消。
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引用次数: 0
Standard of practice in mental health for pharmacy services 药学服务精神卫生实践标准
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-08-08 DOI: 10.1002/jppr.1874
Helen Lowy BSc (Hons), PGDipClinPharm, MPhil, PGDipCounselling, FSHP, Viandro Borja BPharm (Hons), GradCertPharmPrac, MClinPharm, MSHP, Stewart Bailey BPharm, DipMgt, MPS, MSHP, Cecilia Bjorksten BPharm, MPS, MSHP, FACP, AACPA, Alice Kochman BPharm, MClinPharm, MSHP, Judy Longworth BPharm, MPharm (Clin), FSHP, Alistair Meldrum BPharm (Hons), MClinPharm, MSHP, Amy Sieff BBiomedSc, MPharm, GradCertLShip (HlthHumServ), MSHP, Lesley Smith BPharm, AdvPP (II), BCPP, MSHP, Alice Wisdom BPharm (Hons), MSHP, Yee Mellor BPharm, MCncrSc, GPhC, MSHP
Standard of practice in mental health for pharmacy services Helen Lowy, BSc (Hons), PGDipClinPharm, MPhil, PGDipCounselling, FSHP*, Viandro Borja, BPharm (Hons), GradCertPharmPrac, MClinPharm, MSHP, Stewart Bailey, BPharm, DipMgt, MPS, MSHP, Cecilia Bjorksten, BPharm, MPS, MSHP, FACP, AACPA, Alice Kochman, BPharm, MClinPharm, MSHP, Judy Longworth, BPharm, MPharm (Clin), FSHP, Alistair Meldrum, BPharm (Hons), MClinPharm, MSHP, Amy Sieff, BBiomedSc, MPharm, GradCertLShip (HlthHumServ), MSHP, Lesley Smith, BPharm, AdvPP (II), BCPP, MSHP, Alice Wisdom, BPharm (Hons), MSHP, Yee Mellor, BPharm, MCncrSc, GPhC, MSHP 1 Mental Health Leadership Committee, The Society of Hospital Pharmacists of Australia, Abbotsford, Victoria, Australia 2 Helen Lowy Counselling and Psychotherapy, Frankston South, Victoria, Australia 3 Pharmacy Department, Alfred Health, Melbourne, Victoria, Australia 4 Faculty of Pharmacy and Pharmaceutical Science, Monash University, Parkville, Victoria, Australia 5 Pharmacy Department, Darling Downs Health, Toowoomba, Queensland, Australia 6 Hunter New England Mental Health Service, Waratah, New South Wales, Australia 7 Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia 8 The Children’s Hospital at Westmead, Sydney Children’s Hospital Network, Sydney, NSW, Australia 9 Rockhampton Hospital Pharmacy Department, Central Queensland Hospital and Health Service, Rockhampton, Queensland, Australia 10 South Western Sydney Local Health District, Warwick Farm, New South Wales, Australia 11 Pharmacy Department, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia 12 SA Pharmacy, SA Health, Adelaide, South Australia, Australia 13 The Society of Hospital Pharmacists of Australia, Abbotsford, Victoria, Australia
Helen Lowy, BSc(荣誉),PGDipClinPharm, MPhil, pgdipcounseling, FSHP*, Viandro Borja, BPharm(荣誉),GradCertPharmPrac, MClinPharm, MSHP, Stewart Bailey, BPharm, DipMgt, MPS, MSHP, Cecilia Bjorksten, BPharm, MPS, MSHP, BPharm, MSHP, Judy Longworth, BPharm, MPharm(临床),FSHP, Alistair Meldrum, BPharm(荣誉),MClinPharm, MSHP, Amy Sieff, BBiomedSc, MPharm, GradCertLShip (HlthHumServ), MSHP,Lesley Smith, BPharm, AdvPP (II), BCPP, MSHP, Alice Wisdom, BPharm(荣誉),MSHP, Yee Mellor, BPharm, MCncrSc, GPhC, MSHP 1心理健康领导委员会,澳大利亚维多利亚州阿伯茨福德澳大利亚医院药剂师协会2 Helen Lowy咨询和心理治疗,澳大利亚维多利亚州弗兰克斯顿南部3澳大利亚维多利亚州墨尔本阿尔弗雷德健康药房4维多利亚州帕克维尔莫纳什大学药学和药物科学学院澳大利亚5澳大利亚昆士兰州图沃姆巴达令斯健康药房6澳大利亚新南威尔士州沃拉塔亨特新英格兰精神健康服务7澳大利亚维多利亚州海德堡奥斯汀健康药房8澳大利亚新南威尔士州悉尼韦斯特米德儿童医院悉尼儿童医院网络9罗克汉普顿医院药房昆士兰州罗克汉普顿澳大利亚10澳大利亚新南威尔士州沃里克农场西南悉尼地方卫生区11澳大利亚昆士兰州伍龙加巴亚历山德拉公主医院药房12澳大利亚南澳大利亚阿德莱德SA药房13澳大利亚医院药剂师协会阿伯茨福德澳大利亚维多利亚州
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引用次数: 0
A review of pharmacy-led interventions: identification of facilitators and barriers for the design of a new model of care for asthma 药房主导的干预措施综述:确定哮喘新护理模式设计的促进因素和障碍
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-07-31 DOI: 10.1002/jppr.1870
Neera Rajballi-Naidoo BSC.Pharm, PGDipHS, MHSc, Kyle John Wilby PharmD, PhD, Amber Young BPharm, PGCertPharm, PGCertGPP, PhD, Alesha Smith BSc, MSc, PhD, MBA

The objective of this narrative review was to determine the facilitators and barriers identified in pharmacy-led interventions that improve outcomes in patients with asthma and support the implementation of interventions in practice. EMBASE, Web of Science, Google Scholar, and PubMed were used to identify 17 relevant articles. Seven studies were randomised controlled studies and 10 were one-arm, pre-post evaluations of all participants enrolled. Questionnaires assessing asthma control, medicine adherence, and knowledge about asthma were used, while checklists were used to assess inhaler technique. Studies with planned interventions in a clinic or general practice setting and lasting for 6 months (compared to longer interventions of 48 weeks) were more successful in retaining participation in the program. Education was the key intervention in which inhaler technique training was the most common. Knowledge about the disease, its aetiology, trigger factors, and medication used were covered in 10 of the studies. Fifteen of the articles reported an improvement in the asthma of patients receiving intervention by the pharmacist, measured by their asthma control test scores, emergency department visits, or reduced emergency steroid prescriptions. This review highlights five key requirements for the success of pharmacy-based interventions for asthma management: (a) developing and maintaining a skilled workforce; (b) close proximation of a general practitioner practice or clinic to the pharmacy; (c) patient education on the disease and medicine; (d) structured and standardised intervention and assessment; and (e) length of the intervention suitable to the pharmacist and the patient.

这篇叙述性综述的目的是确定在药物主导的干预措施中发现的促进因素和障碍,这些干预措施可以改善哮喘患者的预后,并支持干预措施在实践中的实施。使用EMBASE、Web of Science、b谷歌Scholar和PubMed识别出17篇相关文章。7项研究是随机对照研究,10项是单臂研究,对所有入组参与者进行前后评估。使用问卷评估哮喘控制、药物依从性和哮喘知识,使用检查表评估吸入器技术。在诊所或一般实践环境中进行计划干预的研究,持续6个月(与48周的较长干预相比),更成功地保留了对该计划的参与。教育是最主要的干预措施,其中吸入器技术培训最为常见。其中10项研究涵盖了对这种疾病的了解、病因、触发因素和使用的药物。其中15篇文章报告了接受药剂师干预的患者哮喘的改善,通过他们的哮喘控制测试分数、急诊科就诊或减少紧急类固醇处方来衡量。本综述强调了以药物为基础的哮喘管理干预措施取得成功的五个关键要求:(a)发展和维持一支熟练的劳动力队伍;(b)全科医生的诊所或诊所靠近药房;(c)对患者进行疾病和药物教育;(d)结构化和标准化的干预和评估;(e)适合药剂师和患者的干预时间长度。
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引用次数: 0
Pharmacist ambulatory pain services for a chronic non-cancer pain clinic: a descriptive study 慢性非癌性疼痛门诊的药剂师门诊疼痛服务:一项描述性研究
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-07-30 DOI: 10.1002/jppr.1875
Sam Maleki BPharm, MPharmPrac, Jeremy Szmerling BPharm, Mahisha Thiruvasagan BPharm, MPharmPrac, Gloria Seah FFPMANZCA, FANZCA, MMed(Periop), MBBS, Galahad Gu BPharm(Hons), MPharmPrac

Background

Patients presenting to specialist pain clinics are often prescribed complex and high-risk analgesic regimens. In this setting, pharmacists can help identify at risk patients and provide valuable clinical input to improve patient outcomes.

Aim

To evaluate the role of a clinical pharmacist in improving the triage, assessment and management of patients presenting to ambulatory pain clinics.

Method

This descriptive study enrolled patients from two chronic noncancer pain clinics from July to December 2021. A new clinical pharmacist service was devised, which operated as telehealth one day per week. The pharmacist was responsible for accepting referrals, triaging based on clinic criteria and updating them with prescription risk factors, in line with SafeScript's traffic light system. Pharmacist clinical services included completion of medication histories, drug dose interventions and patient education. This project received departmental ethical approval from the Eastern Health Office of Research and Ethics prior to commencement (Approval No: QA21-068).

Results

The pharmacist assessed 253 patients and identified prescription risk factors for 68 patients; of which 11 (16%) had received opioids from ≥4 prescribers, 10 (15%) were issued a monitored prescription from ≥4 pharmacies, seven (10%) were on high-risk drug combinations, 25 (37%) had an Oral Morphine Equivalent Daily Dose (OMEDD) of 50–100 mg, and 26 (38%) with OMEDD >100 mg. The pharmacist completed 67 medication histories and provided 22 accepted drug intervention recommendations to clinic physicians, including seven recommendations for dose adjustments, six to cease a medicine and nine to start a new medicine.

Conclusion

The pharmacist incorporated SafeScript in the clinics' triage processes and provided valuable clinical interventions complementing the care provided by the pain physicians and the allied health staff.

背景:到疼痛专科诊所就诊的患者通常会被开复杂和高风险的镇痛方案。在这种情况下,药剂师可以帮助识别有风险的患者,并提供有价值的临床投入,以改善患者的预后。目的评价临床药师在改善门诊疼痛患者的分诊、评估和管理方面的作用。方法本描述性研究纳入了2021年7月至12月来自两家慢性非癌性疼痛诊所的患者。设计了一种新的临床药师服务,每周进行一天的远程保健。药剂师负责接受转诊,根据临床标准进行分诊,并根据SafeScript的红绿灯系统更新处方风险因素。药师临床服务包括完成用药史、药物剂量干预和患者教育。该项目在开始之前获得了东部卫生研究和伦理办公室的部门伦理批准(批准号:QA21-068)。结果药师共评估患者253例,确定处方危险因素68例;其中11人(16%)从≥4个处方者处获得阿片类药物,10人(15%)从≥4个药店获得监测处方,7人(10%)使用高危药物组合,25人(37%)口服吗啡当量日剂量(OMEDD)为50-100 mg, 26人(38%)口服吗啡当量日剂量为100 mg。药师完成67例用药史,向临床医师提供22例可接受的药物干预建议,其中7例建议调整剂量,6例建议停药,9例建议开始使用新药物。结论药师将SafeScript纳入临床分诊流程,提供了有价值的临床干预措施,补充了疼痛医师和专职卫生人员提供的护理。
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引用次数: 0
Forgotten but not gone: calcium-alkali syndrome 遗忘而未去:钙碱性综合征
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-07-23 DOI: 10.1002/jppr.1873
Shrey Seth Pharm D, Lukas Kairatis MBBS, FRACP, PhD, Ronald L. Castelino BPharm, MPharm, PhD

Background

Calcium-alkali syndrome (CAS) is characterised by hypercalcaemia, metabolic alkalosis, and renal injury. CAS has been a long-standing concern but has fallen off the radar in recent times. However, supplementation of calcium and vitamin D for osteoporosis, and use of calcium based antacids for reflux has led to its resurgence as one of the leading causes for hypercalcaemia-induced hospitalisations.

Aim

We present a case of CAS owing to excessive consumption of calcium carbonate in the presence of vitamin D.

Clinical details

An 84-year-old woman presented to the hospital emergency room for the second time in 4 months after CAS was missed during the first admission. A history of significant (6–8 tablets daily) Quick-Eze use (calcium carbonate), Gaviscon dual action antacid (calcium carbonate 32.5 mg/mL, sodium bicarbonate 21.3 mg/mL, sodium alginate 50 mg/mL) for reflux, and 2000 IU of vitamin D capsules for osteoporosis was the likely reason for CAS. COVID-19 lockdown and the inability to fill esomeprazole scripts had increased the patient's reliance on over-the-counter treatments for reflux.

Outcomes

The severe hypercalcaemia was treated using intravenous fluids and pamidronate, following which her serum calcium levels normalised, with resolution of symptoms.

Conclusion

The effect of Quick-Eze tablets on the development of hypercalcaemia should not be underestimated, especially in the presence of interacting medicines or supplements. This report highlights the importance of accurate history taking as the hypercalcaemia was missed during the patient's initial visit. Appropriate warning labels are warranted on Quick-Eze tablets, as the current information is ambiguous, with no specific information on duration.

背景钙碱综合征(CAS)以高钙血症、代谢性碱中毒和肾损伤为特征。CAS长期以来一直受到关注,但近年来逐渐淡出人们的视线。然而,补充钙和维生素D治疗骨质疏松症,使用钙基抗酸剂治疗反流,导致其重新成为高钙血症引起住院治疗的主要原因之一。目的:我们报告一例在维生素d存在的情况下,碳酸钙摄入过量导致CAS的病例。临床细节:一名84岁妇女在第一次入院时错过了CAS,在4个月内第二次来到医院急诊室。大量(每天6-8片)快速eze(碳酸钙),加夫iscon双作用抗酸剂(碳酸钙32.5 mg/mL,碳酸氢钠21.3 mg/mL,海藻酸钠50 mg/mL)用于反流,2000 IU维生素D胶囊用于骨质疏松症的历史可能是CAS的原因。COVID-19封锁和无法填写埃索美拉唑处方增加了患者对非处方反流治疗的依赖。结果严重高钙血症患者经静脉输液和帕米膦酸钠治疗后,血钙水平恢复正常,症状缓解。结论速溶片对高钙血症的影响不可低估,特别是在有相互作用的药物或补充剂存在的情况下。本报告强调了准确的病史记录的重要性,因为在患者初次就诊时遗漏了高钙血症。由于目前的信息不明确,没有关于持续时间的具体信息,因此需要在Quick-Eze片剂上贴有适当的警告标签。
{"title":"Forgotten but not gone: calcium-alkali syndrome","authors":"Shrey Seth Pharm D,&nbsp;Lukas Kairatis MBBS, FRACP, PhD,&nbsp;Ronald L. Castelino BPharm, MPharm, PhD","doi":"10.1002/jppr.1873","DOIUrl":"10.1002/jppr.1873","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Calcium-alkali syndrome (CAS) is characterised by hypercalcaemia, metabolic alkalosis, and renal injury. CAS has been a long-standing concern but has fallen off the radar in recent times. However, supplementation of calcium and vitamin D for osteoporosis, and use of calcium based antacids for reflux has led to its resurgence as one of the leading causes for hypercalcaemia-induced hospitalisations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>We present a case of CAS owing to excessive consumption of calcium carbonate in the presence of vitamin D.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical details</h3>\u0000 \u0000 <p>An 84-year-old woman presented to the hospital emergency room for the second time in 4 months after CAS was missed during the first admission. A history of significant (6–8 tablets daily) Quick-Eze use (calcium carbonate), Gaviscon dual action antacid (calcium carbonate 32.5 mg/mL, sodium bicarbonate 21.3 mg/mL, sodium alginate 50 mg/mL) for reflux, and 2000 IU of vitamin D capsules for osteoporosis was the likely reason for CAS. COVID-19 lockdown and the inability to fill esomeprazole scripts had increased the patient's reliance on over-the-counter treatments for reflux.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Outcomes</h3>\u0000 \u0000 <p>The severe hypercalcaemia was treated using intravenous fluids and pamidronate, following which her serum calcium levels normalised, with resolution of symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The effect of Quick-Eze tablets on the development of hypercalcaemia should not be underestimated, especially in the presence of interacting medicines or supplements. This report highlights the importance of accurate history taking as the hypercalcaemia was missed during the patient's initial visit. Appropriate warning labels are warranted on Quick-Eze tablets, as the current information is ambiguous, with no specific information on duration.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"53 5","pages":"268-270"},"PeriodicalIF":2.1,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1873","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45738278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and implementation of an electronic opioid management plan to support consistent communication of opioid analgesia prescribing intentions to patients and general practitioners 设计和实施电子阿片类药物管理计划,以支持与患者和全科医生一致地沟通阿片类止痛药处方意图
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-29 DOI: 10.1002/jppr.1872
Elizabeth Su BPharm(Hons), GradCertPharmPrac, MPharmPrac, CHIA, Parnaz Aminian BPharm(Hons), GradCertPharmPrac, Christopher McMaster MBBS, BSc/BA, GradDipBiostats, CHIA, FRACP, Jade Eyles BPharm(Hons), MPharmPrac, Albert G. Frauman MBBS, MD, FRACP, FACCP, FACP, Kent Garrett BPharm, GradDipHospPharm, Simone E. Taylor BPharm, PharmD, GradCertClinResMeth, David F. L. Liew MBBS, FRACP, CHIA

Opioid prescribing requires careful planning to minimise the risk of serious adverse outcomes. However, documentation of discharge opioid plans for patients and their general practitioners (GPs) is inconsistent, particularly when opioids are commenced in the emergency department or after surgery. We describe an initiative to promote consistent discharge opioid plan communication by implementing an opioid management plan (OMP) in our hospital's electronic medical record. Completion of an electronic form by the prescriber generates an OMP note in the medical history, which is used by the pharmacist to provide tailored opioid patient education. The OMP also populates the discharge summary that is sent to the GP and the Australian national digital health record platform, My Health Record. Preliminary evaluation shows incorporating OMP documentation into routine workflows has assisted prescribers to consistently document the plan for supplied opioids, supporting continuity of care. Workflow optimisation is ongoing to further improve discharge summary documentation and provision of patient-friendly written information. This study was conducted as a quality improvement project and audits conducted as part of the project were approved by Austin Health's Office for Research (Project No: LNR/18/Austin/155). Informed patient consent was not required by Austin Health.

阿片类药物处方需要仔细规划,以最大限度地降低严重不良后果的风险。然而,患者及其全科医生的阿片类药物出院计划文件不一致,尤其是在急诊科或手术后开始使用阿片类物质时。我们描述了一项通过在我们医院的电子病历中实施阿片类药物管理计划(OMP)来促进一致出院阿片类物质计划沟通的举措。处方医生填写电子表格会在病史中生成OMP注释,药剂师使用该注释来提供量身定制的阿片类药物患者教育。OMP还填充出院摘要,该摘要发送给全科医生和澳大利亚国家数字健康记录平台“我的健康记录”。初步评估显示,将OMP文件纳入常规工作流程有助于处方医生始终如一地记录阿片类药物供应计划,支持护理的连续性。正在进行工作流程优化,以进一步改进出院总结文件和提供方便患者的书面信息。这项研究是作为一个质量改进项目进行的,作为该项目的一部分进行的审计得到了奥斯汀卫生研究办公室的批准(项目编号:LNR/18/Austin/155)。Austin Health不要求患者知情同意。
{"title":"Design and implementation of an electronic opioid management plan to support consistent communication of opioid analgesia prescribing intentions to patients and general practitioners","authors":"Elizabeth Su BPharm(Hons), GradCertPharmPrac, MPharmPrac, CHIA,&nbsp;Parnaz Aminian BPharm(Hons), GradCertPharmPrac,&nbsp;Christopher McMaster MBBS, BSc/BA, GradDipBiostats, CHIA, FRACP,&nbsp;Jade Eyles BPharm(Hons), MPharmPrac,&nbsp;Albert G. Frauman MBBS, MD, FRACP, FACCP, FACP,&nbsp;Kent Garrett BPharm, GradDipHospPharm,&nbsp;Simone E. Taylor BPharm, PharmD, GradCertClinResMeth,&nbsp;David F. L. Liew MBBS, FRACP, CHIA","doi":"10.1002/jppr.1872","DOIUrl":"10.1002/jppr.1872","url":null,"abstract":"<p>Opioid prescribing requires careful planning to minimise the risk of serious adverse outcomes. However, documentation of discharge opioid plans for patients and their general practitioners (GPs) is inconsistent, particularly when opioids are commenced in the emergency department or after surgery. We describe an initiative to promote consistent discharge opioid plan communication by implementing an opioid management plan (OMP) in our hospital's electronic medical record. Completion of an electronic form by the prescriber generates an OMP note in the medical history, which is used by the pharmacist to provide tailored opioid patient education. The OMP also populates the discharge summary that is sent to the GP and the Australian national digital health record platform, My Health Record. Preliminary evaluation shows incorporating OMP documentation into routine workflows has assisted prescribers to consistently document the plan for supplied opioids, supporting continuity of care. Workflow optimisation is ongoing to further improve discharge summary documentation and provision of patient-friendly written information. This study was conducted as a quality improvement project and audits conducted as part of the project were approved by Austin Health's Office for Research (Project No: LNR/18/Austin/155). Informed patient consent was not required by Austin Health.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"53 4","pages":"186-194"},"PeriodicalIF":2.1,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48830165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the patient-perceived impact of a neratinib special access program in an Australian community pharmacy 评估患者对澳大利亚社区药房纳拉替尼特殊准入项目的感知影响
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-22 DOI: 10.1002/jppr.1871
Jessie Zhang, Lynn Cheong BPharm, PhD

Background

In Australia, breast cancer is the most commonly diagnosed cancer in women, and improved survival rates have placed an increased burden on the healthcare system. To better utilise community pharmacists in anticancer therapy, a medicine management service for neratinib was initiated in an Australian community pharmacy for patients with breast cancer.

Aim

To explore the experience and satisfaction of Australian breast cancer patients who received a pharmacist medicine management service for their neratinib treatment through a community pharmacy.

Method

Patients enrolled in the neratinib special access program were invited to complete an electronic survey between February–September 2019. A mixed-methods approach was utilised in data analysis. Ethics approval was granted by the University of Canberra Human Research Ethics Committee (Project No: 20181648).

Results

Thirty-three individuals completed the survey. A majority of participants (94%) were either ‘very satisfied’ or ‘satisfied’ with the time the pharmacist spent with them. As part of the service, 88% of participants viewed the first pharmacist session as ‘absolutely’ worthwhile and 79% believed that the pharmacist interaction increased their understanding of neratinib therapy. Many participants supported the continued provision and expansion of the service (88%).

Conclusion

This pilot study provided valuable insights into participants' experiences of a pharmacist medicine management service for neratinib therapy. The unique preferences and health information needs of patients were highlighted. Further investigation is needed to explore how community pharmacists may be best utilised to improve breast cancer care and support patient needs.

在澳大利亚,乳腺癌是女性中最常见的癌症,生存率的提高给医疗保健系统带来了更大的负担。为了更好地利用社区药剂师进行抗癌治疗,澳大利亚一家社区药房开始为乳腺癌患者提供奈拉替尼的药物管理服务。
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引用次数: 0
Overview of factors influencing successful implementation of non-medical prescribing 影响非医疗处方成功实施的因素概述
IF 2.1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-13 DOI: 10.1002/jppr.1868
Mariam Ghabour BPharm, MQM, Kyle John Wilby PharmD, PhD, Caroline J. Morris BPharm (Hons), MSc, PhD, Alesha J. Smith BSc, MSc, MBA, PhD

Aim

This study sought to determine the factors influencing successful implementation of non-medical prescribing (NMP).

Data sources

EMBASE, Medline, CINAHL and reference lists were searched from January 2010 to November 2020.

Study Selection

Umbrella review and narrative synthesis of results were utilised. The retrieved reviews underwent title screening, abstract review, full-text screening and assessment for inclusion. To guarantee the precision of the search results, Participants, Intervention, Control, and Outcomes (PICO) elements were recorded for each study. Studies were included if they were systematic reviews, published in English, published from January 2010 to November 2020, and discussed barriers and/or facilitators to NMP implementation.

Results

Of the 193 studies identified, eight were eligible for inclusion. Most of the reviews (62%) were published in 2017–2018. The majority of the reviews (62%) were focused on the United Kingdom. Three reviews discussed nurse prescribing, two reviews focused on pharmacist prescribing, and three reviews investigated NMP generally. Data were compiled into the Consolidated Framework for Implementation Research to evaluate the factors that influence the success or failure of NMP implementation.

Conclusion

Implementation of NMP is a complex process which requires fulfilment of all its elements. The success of NMP can be directly related to the extent of the whole system engagement and support, and available funding.

本研究旨在确定影响非医学处方(NMP)成功实施的因素。
{"title":"Overview of factors influencing successful implementation of non-medical prescribing","authors":"Mariam Ghabour BPharm, MQM,&nbsp;Kyle John Wilby PharmD, PhD,&nbsp;Caroline J. Morris BPharm (Hons), MSc, PhD,&nbsp;Alesha J. Smith BSc, MSc, MBA, PhD","doi":"10.1002/jppr.1868","DOIUrl":"10.1002/jppr.1868","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study sought to determine the factors influencing successful implementation of non-medical prescribing (NMP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Data sources</h3>\u0000 \u0000 <p>EMBASE, Medline, CINAHL and reference lists were searched from January 2010 to November 2020.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Selection</h3>\u0000 \u0000 <p>Umbrella review and narrative synthesis of results were utilised. The retrieved reviews underwent title screening, abstract review, full-text screening and assessment for inclusion. To guarantee the precision of the search results, Participants, Intervention, Control, and Outcomes (PICO) elements were recorded for each study. Studies were included if they were systematic reviews, published in English, published from January 2010 to November 2020, and discussed barriers and/or facilitators to NMP implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 193 studies identified, eight were eligible for inclusion. Most of the reviews (62%) were published in 2017–2018. The majority of the reviews (62%) were focused on the United Kingdom. Three reviews discussed nurse prescribing, two reviews focused on pharmacist prescribing, and three reviews investigated NMP generally. Data were compiled into the Consolidated Framework for Implementation Research to evaluate the factors that influence the success or failure of NMP implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Implementation of NMP is a complex process which requires fulfilment of all its elements. The success of NMP can be directly related to the extent of the whole system engagement and support, and available funding.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"53 4","pages":"155-170"},"PeriodicalIF":2.1,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1868","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47273155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Pharmacy Practice and Research
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