Journal of Orthopaedic Science最新文献

{"title":"The prevalence and characteristics of diffuse idiopathic skeletal hyperostosis in the community-living middle-aged and elderly population: The Yakumo study","authors":"Kazuma Ohshima ,&nbsp;Hiroaki Nakashima ,&nbsp;Naoki Segi ,&nbsp;Sadayuki Ito ,&nbsp;Jun Ouchida ,&nbsp;Yasuhiko Takegami ,&nbsp;Shinya Ishizuka ,&nbsp;Yukiharu Hasegawa ,&nbsp;Shiro Imagama","doi":"10.1016/j.jos.2023.10.005","DOIUrl":"10.1016/j.jos.2023.10.005","url":null,"abstract":"<div><h3>Background</h3><div>The incidence of diffuse idiopathic skeletal hyperostosis (DISH) is increasing with the aging of the population. Asymptomatic DISH can decrease the spinal range of motion (ROM) and cause fractures. However, the prevalence or physical function of patients with DISH before experiencing fractures and other serious conditions is unclear. This study aimed to investigate the prevalence of DISH in the community residents on the basis of age and sex and characterize their physical function, ROM, and bone fragility.</div></div><div><h3>Methods</h3><div>The subjects were community volunteers who attended a health checkup in 2018 and 2019. Overall, 455 subjects (mean age, 64.2 ± 9.7 years; 177 men) were included for analysis. We performed whole-spine lateral radiography for detecting DISH according to the criteria reported by Resnick. We compared the age, sex, body mass index<span> (BMI), results of muscle strength and walking tests, ROM measured by SpinalMouse®, and quantitative ultrasound (QUS) of calcaneus with and without DISH.</span></div></div><div><h3>Results</h3><div>DISH was detected in 83 (18.2%) cases. The DISH group was older (69.8 y.o. vs. 63.0 y.o.; p &lt; 0.05) and comprised more men (prevalence: men, 27.7%; women, 12.2%; p &lt; 0.001). BMI was high in the DISH group (24.8 vs. 23.3 kg/m²<span>, p &lt; 0.05). SpinalMouse measurements showed the DISH group had a significantly decreased ROM in the lumbar spine (43.2°, 57.2°, p &lt; 0.05). The DISH group had a significantly lower T-score on the QUS measurement in the calcaneus (−2.0, −1.5, p &lt; 0.05). There were, however, no significant differences between groups in both muscle strength test and walking test.</span></div></div><div><h3>Conclusion</h3><div>Subjects with DISH had decreased ROM in the lumbar spine and bone mineral density in calcaneal QUS. However, physical functions such as muscle strength and walking ability were similar among subjects with and without DISH without subjective symptoms.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1346-1352"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49691067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of conversion surgery after conservative treatment for pyogenic spondylitis","authors":"Tetsuhiko Inoue ,&nbsp;Naomi Kobayashi ,&nbsp;Noriyuki Baba ,&nbsp;Manabu Ide ,&nbsp;Takayuki Higashi ,&nbsp;Yutaka Inaba","doi":"10.1016/j.jos.2023.10.015","DOIUrl":"10.1016/j.jos.2023.10.015","url":null,"abstract":"<div><h3>Background</h3><div><span>Patient demographic and clinical characteristics may be factors associated with the success of conservative treatment for pyogenic spondylitis<span>. The ability of imaging findings at initial diagnosis to predict patient outcomes remains unclear. The aim of this study was to investigate the risk factors associated with conversion surgery after conservative treatment for pyogenic spondylitis, with a special focus on the initial </span></span>computed tomography (CT) findings.</div></div><div><h3>Methods</h3><div>This study enrolled 35 patients with pyogenic spondylitis who underwent CT and magnetic resonance imaging (MRI) at diagnosis and were followed-up for more than 6 months. Patients were diagnosed by MRI, and the degree of bone destruction was assessed on CT cross-sectional images. Vertebral body destruction was classified as grades 0 (almost normal), 1 (endplate irregularity), 2 (vertebral body destruction not involving the posterior wall), and 3 (destruction involving the posterior wall). Patients were divided into four groups based on grade of bone destruction and their clinical characteristics were compared.</div></div><div><h3>Results</h3><div>1, 11, 11, and 12 patients were classified as grades 0, 1, 2, and 3, respectively. Univariate analysis<span> showed no significant differences in the demographic and clinical characteristics of the four groups. Eighteen (51.4 %) patients had been treated surgically, with the rate of surgical treatment being significantly higher in patients with grade 3 (83.3 %) than in those with grades 0 + 1 (25 %) and grade 2 (45.5 %) (P &lt; 0.05). Multivariate analysis<span> showed that epidural abscess on MRI (odds ratio [OR] 10.8, 95 % confidence interval [CI] 1.68–69.7), grade 3 bone destruction on CT (OR 3.97, 95 % CI 1.21–13.0), and C-reactive protein (CRP) improvement rate after 1 week of treatment (OR 0.95, 95 % CI 0.91–0.99) were risk factors for surgery.</span></span></div></div><div><h3>Conclusions</h3><div>Early surgical treatment should be considered for patients with pyogenic spondylitis who present with an epidural abscess on MRI and bone destruction extending to the posterior wall on CT at the time of diagnosis.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1376-1381"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72014628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone formation of the coracoid bone graft after the Bristow procedure assessed using three-dimensional computed tomography","authors":"So Minokawa ,&nbsp;Yozo Shibata ,&nbsp;Terufumi Shibata ,&nbsp;Hidetomo Kosaka ,&nbsp;Teruaki Izaki","doi":"10.1016/j.jos.2023.11.010","DOIUrl":"10.1016/j.jos.2023.11.010","url":null,"abstract":"<div><h3>Background</h3><div>The Bristow procedure has been shown to be a reliable method to prevent recurrent anterior shoulder<span><span> instability by compensating for glenoid bone loss and producing the sling effect. The degree of postoperative morphological change in the coracoid </span>bone graft<span><span> is speculated to influence glenohumeral joint stability; however, the details of these changes after the Bristow procedure remain unknown. This study was performed to quantify the postoperative change in the coracoid bone graft volume as assessed by three-dimensional </span>computed tomography (3D-CT).</span></span></div></div><div><h3>Methods</h3><div>The Bristow procedure was performed on 17 shoulders in 17 patients from August 2018 to January 2020. All patients were men, and their mean age at surgery was 17.9 years. The mean follow-up duration was 21.4 months. Within the first week after the operation (Time 0) and at the final follow-up, 3D-CT was used to determine the total coracoid bone graft volume. The clinical outcomes were evaluated using the Japanese Orthopaedic Association (JOA) shoulder score, the University of California Los Angeles (UCLA) shoulder score, and the Western Ontario Shoulder Instability Index (WOSI).</div></div><div><h3>Results</h3><div>The mean volume of the total coracoid bone graft was 1.26 ± 0.29 cm³ at Time 0 and 1.90 ± 0.36 cm³ at the final follow-up (<em>p</em><span> &lt; 0.0001). The mean JOA score, UCLA score, and WOSI were significantly better at the final follow-up than preoperatively (</span><em>p</em><span> &lt; 0.001). No postoperative infection, neurovascular injury, or recurrent instability of the glenohumeral joint occurred.</span></div></div><div><h3>Conclusions</h3><div>In the Bristow procedure, the volume of the total coracoid bone graft as shown by 3D-CT was significantly greater at the final follow-up than at Time 0, and bone formation of the coracoid bone graft was found after the Bristow procedure.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1382-1388"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment experience with continuous local antibiotic perfusion for periprosthetic joint infection","authors":"Yoshiaki Miyake,&nbsp;Toru Takagi","doi":"10.1016/j.jos.2023.12.001","DOIUrl":"10.1016/j.jos.2023.12.001","url":null,"abstract":"<div><h3>Background</h3><div><span>Antibiotic concentrations 100–1000 times higher than the </span>minimum inhibitory concentration<span> are necessary for eradicating biofilms in periprosthetic joint infections (PJI). Achieving this with intravenous antibiotics is challenging, but continuous local antibiotic perfusion (CLAP) can increase the local concentration of antibiotics. Although there are several reports on CLAP therapy in the fracture-related infection, there are only few reports on its application in PJI. Here, we report our experience with CLAP therapy for PJI.</span></div></div><div><h3>Methods</h3><div>Eight patients with PJI (two males and six females, with mean age of 73.5 years [±11.6]) were treated at our department, and their clinical characteristics were analyzed. The parameters considered were the classification of PJI, surgical procedure, duration of CLAP, duration of transvenous antibiotic administration, time of CRP-negative status, whether the infection resolved or recurred, and whether there were complications due to CLAP.</div></div><div><h3>Results</h3><div>Initial surgery included total knee arthroplasty<span><span><span><span><span> in five cases, unicompartmental knee </span>arthroplasty in one case, and </span>total hip arthroplasty in two cases. There were four cases of early </span>postoperative infection<span><span>, two of acute delayed infection, and two of chronic delayed infection. The surgical procedures performed were two-stage revision for two patients, and debridement, antibiotics, and implant retention (DAIR) for the other six. The mean durations of CLAP and transvenous antibiotic administration were 8.5 (±2.4) and 22.4 days (±13.7), respectively, and the mean time to CRP-negative status was 23.3 days (±10.7). All eight patients successfully resolved without additional irrigation or debridement, and no recurrence was observed at the last follow-up after discontinuation of oral antibiotics. No systemic </span>side effects of </span></span>gentamicin or other complications associated with CLAP were observed.</span></div></div><div><h3>Conclusion</h3><div>All patients achieved infection resolution with the combined use of CLAP. This suggests that CLAP is a useful treatment option for PJI.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1469-1476"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone marrow edema in the acromioclavicular joint after arthroscopic rotator cuff repair","authors":"Yukihiro Kajita ,&nbsp;Ryosuke Takahashi ,&nbsp;Ryosuke Sagami ,&nbsp;Yohei Harada ,&nbsp;Yusuke Iwahori","doi":"10.1016/j.jos.2023.12.003","DOIUrl":"10.1016/j.jos.2023.12.003","url":null,"abstract":"<div><h3>Background</h3><div><span>Bone marrow edema (BME) in the </span>acromioclavicular joint<span> (ACj) may occur after arthroscopic rotator cuff<span> repair (ARCR), resulting in persistent postoperative ACj pain. We investigated the incidence and clinical characteristics of BME in ACj after ARCR.</span></span></div></div><div><h3>Methods</h3><div><span>Patients exhibiting ACj-related symptoms prior to ARCR surgery, no BME in the ACj on MRI, and an ability to undergo 2-year postoperative physical and MRI examinations of the ACj were included. Patients who underwent distal clavicle resection or osteophyte resection below the ACj and those unable to achieve primary repair of the rotator cuff were excluded. MRI evaluation was performed preoperatively and at 3, 6, 12, and 24 months postoperatively. Patients who showed BME in ACj on fat-suppressed T2 MRI at 24 months postoperatively were classified into the BME + group, and those with no BME were classified into the BME− group. Patient background, operation time, Japanese Orthopedic Association (JOA) score, re-tear rate, ACj tenderness, and cross-body </span>adduction test were compared between groups. In addition, we examined the time of occurrence of BME.</div></div><div><h3>Results</h3><div>A total of 345 ARCRs were performed during the study period. After the exclusion of 114 shoulders, the remaining 231 shoulders were included in this study. There were 208 cases in the BME− group and 23 cases in the BME + group. The incidence of BME was 9.96 %. Although the JOA scores of both groups showed a significant improvement postoperatively compared to preoperatively, there was no significant difference between the two groups. In terms of re-tear, there was 1 case in the BME + group and 7 in the BME− group. Positive ACj tenderness and cross-body adduction test were significantly higher in the BME + group (<em>P</em> &lt; 0.001). BME occurred in 6 cases at 3 months, 9 cases at 6 months, and 8 cases at 1 year postoperatively. None of the patients developed BME at more than 1 year postoperatively. BME was observed on MRI in all cases at 2 years postoperatively.</div></div><div><h3>Conclusions</h3><div>The rate of occurrence of BME in the ACj after ARCR was 9.96 %. Patients with BME were significantly more likely to have ACj tenderness and positive cross-body adduction test. BME in the ACj often occurs within 6 months to 1 year after ARCR of small-to-medium rotator cuff tears<span>, suggesting a relationship with postoperative functional improvement of the shoulder joint. The ACj should be considered as a potential site of persistent pain after ARCR for small-to-medium rotator cuff tears.</span></div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1389-1394"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139027251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term antibacterial activity of silver-containing hydroxyapatite coatings against Staphylococcus aureus in vitro and in vivo","authors":"Sakumo Kii ,&nbsp;Hiroshi Miyamoto ,&nbsp;Masaya Ueno ,&nbsp;Iwao Noda ,&nbsp;Akira Hashimoto ,&nbsp;Takema Nakashima ,&nbsp;Takeo Shobuike ,&nbsp;Shunsuke Kawano ,&nbsp;Motoki Sonohata ,&nbsp;Masaaki Mawatari","doi":"10.1016/j.jos.2023.10.009","DOIUrl":"10.1016/j.jos.2023.10.009","url":null,"abstract":"<div><h3>Background</h3><div><span>The potential of silver-containing hydroxyapatite (Ag-HA) coatings to prevent orthopaedic implant-associated infection was explored previously; however, the resistance of Ag-HA coatings to late-onset orthopaedic infections is unknown. This study aimed to evaluate the long-term Ag</span>⁺<span> elution and antibacterial properties of the Ag-HA coatings through </span><em>in vitro</em> and <em>in vivo</em> experiments.</div></div><div><h3>Methods</h3><div><span>Ag-HA-coated disc specimens were immersed in fetal bovine serum<span> (FBS) for six months. Ag concentration was measured over time using inductively coupled plasma-mass spectrometry to evaluate Ag release. The hydroxyapatite (HA)- or Ag-HA-coated disc specimens were immersed in FBS for 3 months to elute Ag</span></span>⁺ for <em>in vitro</em> experiments. Methicillin-resistant <em>Staphylococcus aureus</em><span> (MRSA) suspensions were inoculated onto each disc; after 48 h, the number of colonies and the biofilm volume were measured. HA- or Ag-HA-coated disc specimens were inserted under the skin of Sprague-Dawley rats for three months for </span><em>in vivo</em> experiments. In <em>in vivo</em> experiment 1, specimens were inoculated with MRSA and the number of colonies was counted after 48 h. In <em>in vivo</em> experiment 2, the specimens were inoculated with bioluminescent <em>S. aureus</em><span> Xen36 cells, and bioluminescence was measured using an </span><em>in vivo</em> imaging system.</div></div><div><h3>Results</h3><div>The Ag-HA-coated disc specimens continued to elute Ag⁺ after six months. The biofilm volume in the Ag-HA group was lower than in the HA group. In <em>in vitro</em> and <em>in vivo</em><span> experiment 1, the bacterial counts in the Ag-HA group were lower than those in the HA group. In </span><em>in vivo</em><span> experiment 2, the bioluminescence in the Ag-HA group was lower than that in the HA group on days 1–7 after inoculation.</span></div></div><div><h3>Conclusions</h3><div>The Ag-HA-coated discs continued to elute Ag⁺<span> for a long period and exhibited antibacterial activity and inhibition of biofilm formation against </span><em>S. aureus</em>. The Ag-HA coatings have the potential to reduce late-onset orthopaedic implant-associated infections.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1503-1512"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71482768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do standardization of the procedure reduce measurement variability of the sonographic anterior drawer test of the ankle?","authors":"Shuhei Iwata ,&nbsp;Satoshi Yamaguchi ,&nbsp;Seiji Kimura ,&nbsp;Soichi Hattori ,&nbsp;Jun Sasahara ,&nbsp;Ryuichiro Akagi ,&nbsp;Kentaro Amaha ,&nbsp;Tomonori Atsuta ,&nbsp;Noriyuki Kanzaki ,&nbsp;Koji Noguchi ,&nbsp;Hirokazu Okada ,&nbsp;Toru Omodani ,&nbsp;Hiroshi Ohuchi ,&nbsp;Hiroyuki Sato ,&nbsp;Satoshi Takada ,&nbsp;Kenji Takahashi ,&nbsp;Yuichi Yamada ,&nbsp;Tetsuro Yasui ,&nbsp;Takuji Yokoe ,&nbsp;Shun Fukushima ,&nbsp;Seiji Ohtori","doi":"10.1016/j.jos.2023.11.006","DOIUrl":"10.1016/j.jos.2023.11.006","url":null,"abstract":"<div><h3>Background</h3><div>In quantitative ankle stress sonography, different examiners use different techniques, which may cause measurement variability. This study aimed to clarify whether standardizing stress sonography techniques reduces variability in the quantitative measurement of anterior talofibular ligament length change.</div></div><div><h3>Methods</h3><div>Fourteen examiners with a mean ultrasound experience of 8.7 years participated in this study. Each examiner performed stress ultrasonography of the ankle using their preferred method on one patient with an intact anterior talofibular ligament (Patient 1) and on two patients with chronic ankle instability (Patient 2 and 3). Changes in the ligament length between the resting and stressed positions were determined. A consensus meeting was then conducted to standardize the sonographic technique, which was used by the examiners during a repeat stress sonography on the same patients. The variance and measured values were compared between the preferred and standardized techniques using F-tests and paired t-tests, respectively.</div></div><div><h3>Results</h3><div>At a consensus meeting, a sonographic technique in which the examiner pushed the lower leg posteriorly against the fixed foot was adopted as the standardized technique. In Patient 1, the change in the anterior talofibular ligament length was 0.4 (range, −2.3–1.3) mm and 0.6 (−0.6–1.7) mm using the preferred and standardized techniques, respectively, with no significant difference in the variance (<em>P</em> = 0.51) or the measured value (<em>P</em> = 0.52). The length changes in Patient 2 were 2.0 (0.3–4.4) mm and 1.7 (−0.9–3.8) mm using the preferred and standardized techniques, respectively. In Patient 3, the length changes were 1.4 (−2.7–7.1) mm and 0.7 (−2.0–2.3) mm. There were no significant differences between the techniques in either patient group.</div></div><div><h3>Conclusion</h3><div>Variability in the quantitative measurement of ankle stress sonography was not reduced despite the standardization of the technique among examiners. Hence, comparing the measured values between different examiners should be avoided.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1438-1444"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138299300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological and histological evaluation of the tendon-bone junction in porcine shoulders to create a rotator cuff tear and repair model","authors":"Hideyuki Sasanuma ,&nbsp;Tsuneari Takahashi ,&nbsp;Shigeo Kawai ,&nbsp;Akihiro Saitsu ,&nbsp;Wataru Kurashina ,&nbsp;Yuki Iijima ,&nbsp;Tomohiro Saito ,&nbsp;Katsushi Takeshita","doi":"10.1016/j.jos.2023.11.011","DOIUrl":"10.1016/j.jos.2023.11.011","url":null,"abstract":"<div><h3>Background</h3><div><span>This study aimed to morphologically and histologically examine whether pig is useful as models for </span>rotator cuff tear (RCT).</div></div><div><h3>Methods</h3><div><span>The morphology of the scapula<span><span><span><span><span> and humerus bones was evaluated by taking X-ray and three-dimensional </span>computed tomography (3D CT) scans of the right shoulders of five female pigs (age: 4 months). The </span>rotator cuff (RC) footprint at the humeral insertion of these was observed and its shape was measured. Next, they underwent </span>general anesthesia<span> and an acute rotator cuff tear/rotator cuff repair (RCT/RCR) model was created using a deltoid split approach. Four weeks after surgery, the animals were euthanized, the shoulder joints were harvested, and the repaired RC was evaluated by </span></span>hematoxylin and </span></span>eosin<span> staining and toluidine blue staining.</span></div></div><div><h3>Results</h3><div><span>The scapula<span> of the pig had a vestigial </span></span>acromion<span><span>, in contrast to that in humans. The supraspinatus and infraspinatus tendons were connected so as to overlap each other and attached to the postero-superior part of the greater tuberosity. These tendons were located extra-articularly, separate from the joint capsule. The average antero-posterior length of the </span>foot print was 17.4 ± 0.7 mm on the medial margin and 19.1 ± 2.2 mm on the lateral margin. The maximum medial-to-lateral width of it was 5.1 ± 0.5 mm. In all RCT/RCR models at 4 weeks after surgery, the repaired RC compound tendon was visually confirmed to be continuous with the footprint. Histologically, it was confirmed that regeneration of the four-layer structure of the bone-tendon junction had occurred.</span></div></div><div><h3>Conclusion</h3><div><span><span>Porcine supraspinatus and infraspinatus attachment to the greater tuberosity have a structure similar to that of sheep and </span>dogs, which is advantageous for creating the RCT/RCR model. It might be used for future in vivo studies of shoulder </span>joint diseases.</div></div><div><h3>The Translational Potential of this Article</h3><div>Pigs could potentially serve as a viable model for rotator cuff tears.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1521-1527"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138440894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of radial shock wave therapy on rat models of adjuvant arthritis","authors":"Yu Hiraoka ,&nbsp;Nobuyasu Ochiai ,&nbsp;Miyako Narita ,&nbsp;Eiko Hashimoto ,&nbsp;Shohei Ise ,&nbsp;Kenta Inagaki ,&nbsp;Fumiya Hattori ,&nbsp;Seiji Ohtori","doi":"10.1016/j.jos.2023.11.008","DOIUrl":"10.1016/j.jos.2023.11.008","url":null,"abstract":"<div><h3>Background</h3><div><span><span>Extracorporeal shock wave therapy (ESWT) is an effective treatment for </span>musculoskeletal pain, </span>tendinopathy<span>, and fasciitis<span> with an anti-inflammatory effect. ESWT can be categorized into two groups: radial pressure wave (RPW) and focused shock wave (FSW). Although there have been several studies on the inflammation and pain-improvement mechanisms of FSW, there are few studies on the pain-improvement mechanisms of RPW. This study aimed to elucidate the efficacy of RPW in a rat model of adjuvant arthritis.</span></span></div></div><div><h3>Methods</h3><div>Ninety-six rats were randomly categorized into three groups: RPW, control, and sham as follows: (I) RPW group, which received RPW application after complete Freund's adjuvant<span> (CFA) injection; (II) Control group, which received only CFA injection; and (III) Sham group, which received only saline injection. All rats were evaluated at 0, 4, 7, 14, 28, and 56 days post-RPW application based on foot circumference, von Frey test, and immunohistochemistry of nerve fibers for calcitonin gene-related peptide (CGRP) and protein gene product (PGP) 9.5 in plantar skins.</span></div></div><div><h3>Results</h3><div>There were no significant differences in foot circumference between the RPW and control groups at any time point. The RPW group showed significant improvements in the von Frey test results on days 7 and 14. The total CGRP-immunoreactive (ir) and PGP9.5-ir nerve fiber lengths in the RPW group decreased on day 0; however, both were increased in the control group. The CGRP-ir and PGP9.5-ir nerve fibers in the RPW group were significantly shorter than those in the control group until day 14 after RPW.</div></div><div><h3>Conclusions</h3><div><span>RPW improved the mechanical hypersensitivity between days 7 and 14 after application. Like FSW, RPW also induced the degeneration of sensory nerve fibers in the skin in the early period after irradiation, and </span>reinnervation occurred between 14 and 28 days. Thus, our results demonstrate one of the pain relief mechanisms after RPW application.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1513-1520"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138477960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive factors for reoperation after periprosthetic femoral fracture: A retrospective multicenter (TRON) study","authors":"Manato Iwata ,&nbsp;Yasuhiko Takegami ,&nbsp;Katsuhiro Tokutake ,&nbsp;Hiroshi Kurokawa ,&nbsp;Hideomi Takami ,&nbsp;Satoshi Terasawa ,&nbsp;Tetsuro Takatsu ,&nbsp;Shiro Imagama","doi":"10.1016/j.jos.2023.11.016","DOIUrl":"10.1016/j.jos.2023.11.016","url":null,"abstract":"<div><h3>Background</h3><div><span>The surgical treatment of periprosthetic femoral fracture (PFF) can be technically demanding and it is associated with high rates of complications and repeat surgery. However, repeat surgery is uncommon and few studies have examined survival and the functional prognosis following </span>reoperation<span> after the surgical treatment of PFF. We aimed to estimate the rate of reoperation for any reason, to determine the survival rate after reoperation for PFF, and to identify predictors associated with reoperation after PFF surgery in a multicenter (TRON group) study.</span></div></div><div><h3>Methods</h3><div>Two hundred forty-six patients were admitted for treatment of PFF. After excluding patients managed conservatively and those with Vancouver type A fracture, we analyzed 184 patients. Unadjusted risk ratios (RRs) were calculated, and multiple logistic regression was used to calculate adjusted RRs. We used the Kaplan-Meier method to create survival curves and a log-rank test to determine survival from the date of repeat surgery.</div></div><div><h3>Results</h3><div>Fifteen of the 184 patients (8.2 %) underwent reoperation after PFF surgery. The 1-year survival rate after reoperation for PFF was 66.7 % (11 of 15). Vancouver B3 and Vancouver C were identified as independent risk factors for reoperation after PFF surgery (Vancouver B3: Risk ratio [RR] 19.0, 95 % CI 1.10–329 P &lt; 0.001; Vancouver C: RR 13.3, 95 % CI 1.4–123.0, P = 0.023).</div></div><div><h3>Conclusion</h3><div>The reoperation rate after PFF surgery and the mortality after reoperation PFF surgery were relatively high. The fracture type is associated with reoperation after PFF surgery.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"29 6","pages":"Pages 1445-1450"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}