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PNI is useful for predicting the prognosis of patients with soft tissue sarcoma: A retrospective study. PNI有助于预测软组织肉瘤患者的预后:一项回顾性研究。
IF 1.7 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-18 DOI: 10.1016/j.jos.2024.08.005
Keiju Saito,Yusuke Kawabata,Ikuma Kato,Satoru Shinoda,Kenta Hayashida,Shintaro Fujita,Tomotaka Yoshida,Hyonmin Choe,Masanobu Takeyama,Yutaka Inaba
BACKGROUNDIt is known that preoperative Prognostic Nutritional Index (PNI) is useful in predicting prognosis in gastrointestinal diseases and that preoperative improvement of nutritional status improves prognosis. However, there have been few large-scale reports examining the prognostic value of PNI in soft tissue sarcomas. Therefore, the aim of this study is to investigate whether the PNI can be useful for predicting overall survival in soft tissue sarcoma.METHODSBetween January 2006 and March 2022 at our hospital, 111 patients with pathologically diagnosed soft tissue sarcoma were included, retrospectively. Several nutritional or inflammatory biomarkers such as PNI were calculated from the pretreatment blood sample results. The patients were classified into two groups (low and high groups) based on the median value of each parameter. Overall survival was analyzed by the Kaplan‒Meier method and log-rank test. Univariate and multivariate analyses using the Cox proportional hazards model were used to investigate prognostic factors for overall survival.RESULTSThe median overall survival was 24.3 months (mean 37.3 months), and the high PNI group had a significantly longer overall survival than the low PNI group (p < 0.0001). PNI was the most significant univariate factor for overall survival among other nutritional and inflammatory parameters (HR: 5.64, 95% CI: 2.26-14.12, p = 0.0002). The multivariate proportional hazards model was built using variables with prognostic potential as suggested by previous analysis with respect to patient characteristics and PNI. As potential confounding factors, we included PNI, stage, age, and tumor location. PNI was also an independent prognostic factor in multivariate analysis (HR: 7.02, CI: 2.52-19.40, p = 0.0002).CONCLUSIONPNI is a useful prognostic factor among various parameters for overall survival in patients with soft tissue sarcoma.
背景众所周知,术前预后营养指数(PNI)有助于预测胃肠道疾病的预后,术前改善营养状况可改善预后。然而,很少有大规模的报告研究 PNI 在软组织肉瘤中的预后价值。因此,本研究旨在探讨 PNI 是否有助于预测软组织肉瘤的总生存率。方法2006 年 1 月至 2022 年 3 月期间,我院回顾性纳入了 111 例病理诊断为软组织肉瘤的患者。根据治疗前的血样结果计算出几种营养或炎症生物标志物,如 PNI。根据各参数的中位值将患者分为两组(低组和高组)。总生存率采用卡普兰-梅耶法和对数秩检验进行分析。结果中位总生存期为 24.3 个月(平均 37.3 个月),高 PNI 组的总生存期明显长于低 PNI 组(P < 0.0001)。在其他营养和炎症参数中,PNI 是影响总生存期最重要的单变量因素(HR:5.64,95% CI:2.26-14.12,P = 0.0002)。多变量比例危险度模型是根据先前有关患者特征和 PNI 的分析所提出的具有预后潜力的变量建立的。作为潜在的混杂因素,我们纳入了 PNI、分期、年龄和肿瘤位置。在多变量分析中,PNI 也是一个独立的预后因素(HR:7.02,CI:2.52-19.40,P = 0.0002)。
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引用次数: 0
Effectiveness of early cervical functional exercise in patients after anterior cervical discectomy and fusion: A randomized controlled trial. 颈椎前路椎间盘切除和融合术后患者早期颈椎功能锻炼的效果:随机对照试验。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.jos.2024.08.004
Zhao-Rui Wang, Meng Zhang, Bang Wang, Xing-Bin Li, Ai-Bing Huang

Objective: To observe the effect of early cervical functional exercise (CFE) on clinical outcomes and safety of patients after anterior cervical discectomy and fusion (ACDF).

Methods: Sixty patients who underwent ACDF from September 2019 to September 2020 were analyzed and randomly divided into two groups: the CFE group (27 cases) and the usual care (UC) group (33 cases). Then, all patients in the two groups received routine postoperative guidance care at the same time. Besides, the patients of the CFE group underwent a cervical functional exercise program after on the third day after ACDF. The evaluation was conducted preoperatively and at 1 week, 1 month and 6 months after surgery. The Visual Analogue Scale (VAS), Neck Disability Index (NDI) and Japanese Orthopaedic Association scores (JOA) were used to assess clinical outcomes and the safety was confirmed with routine postoperative radiological visits to ensure intervertebral stability.

Results: The CFE group reported lower neck pain scores on VAS at 1 month after surgery (P = 0.02) and higher postoperative scores by JOA at 1 month and 6 months, neck disability on NDI at 1 week, 1 month and 6 months after surgery (P < 0.05) compared to the UC group. For postoperative dysfunction, the CFE group had more significant changes than the UC group at 1 month and 6 months after surgery (P < 0.05). There was no statistical difference in cervical curves, fusion rate and fusion status between the two groups, and no revision surgery was recorded although a patient has one screw partially back out in UC group.

Conclusion: Our study suggested that the cervical functional exercise could decrease cervical pain and improve postoperative function in patients after ACDF. It was a safe and effective treatment for postoperative rehabilitation. The use of a postoperative collar, especially for one or two-level ACDF may not be needed.

Protocol identifying number: This trial was registered in the Chinese Clinical Trial Registry (registration number: ChiCTR1900025569) on 01/09/2019.

目的观察早期颈椎功能锻炼(CFE)对颈椎前路椎间盘切除融合术(ACDF)后患者临床疗效及安全性的影响:分析2019年9月至2020年9月期间接受ACDF的60例患者,并将其随机分为两组:CFE组(27例)和常规护理(UC)组(33例)。然后,两组所有患者同时接受术后常规指导护理。此外,CFE 组患者在 ACDF 术后第三天开始进行颈椎功能锻炼。评估在术前、术后一周、一个月和六个月进行。采用视觉模拟量表(VAS)、颈部残疾指数(NDI)和日本骨科协会(JOA)评分来评估临床效果,并通过术后常规放射学检查来确保椎体间的稳定性:结果:CFE 组术后 1 个月的 VAS 颈部疼痛评分较低(P = 0.02),术后 1 个月和 6 个月的 JOA 评分较高,术后 1 周、1 个月和 6 个月的 NDI 颈部残疾评分较高(P 结论:CFE 术后 1 个月的 VAS 颈部疼痛评分较低(P = 0.02),术后 1 个月和 6 个月的 JOA 评分较高:我们的研究表明,颈椎功能锻炼可减轻 ACDF 术后患者的颈椎疼痛并改善其术后功能。这是一种安全有效的术后康复治疗方法。术后可能不需要使用颈圈,尤其是对于一、二级 ACDF:本试验于2019年9月1日在中国临床试验注册中心注册(注册号:ChiCTR1900025569)。
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引用次数: 0
Effects of lower limb vibration on hip pain and function after total hip arthroplasty: A randomized controlled trial. 下肢振动对全髋关节置换术后髋部疼痛和功能的影响:随机对照试验
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-02 DOI: 10.1016/j.jos.2024.08.003
Hisashi Ikutomo, Masatoshi Nakamura, Kenichi Okamura, Keiichi Togomori, Norikazu Nakagawa, Kensaku Masuhara

Background: A vibration roller is an effective tool for reducing muscle soreness and improving damaged muscle function. However, its efficacy in reducing hip pain and improving function after total hip arthroplasty is unclear. We investigated the effect of lower limb vibration using a vibration roller on postoperative hip pain and function after total hip arthroplasty in a randomized controlled clinical trial.

Methods: Thirty patients scheduled for total hip arthroplasty were randomly assigned to vibration and control groups. The patients in the vibration group performed lower limb vibration using a vibration roller. The patients in the control group performed sham therapy using a hot pack. Patients performed both interventions for 10 min daily on postoperative days 1-7, in addition to regular physical therapy. Primary outcome was hip pain intensity as measured using a visual analog scale. Secondary outcomes were pain-pressure threshold and serum creatine kinase and C-reactive protein levels. We also assessed physical functions, including the Harris Hip Score, range of motion of the hip joint, muscle strength, gait velocity, and timed up-and-go test. The effects of the interventions on outcome measurements in the groups were compared using a split-plot design variance analysis.

Results: After one week of the intervention and three weeks of follow-up, the vibration group showed statistically significant improvement in the exercise-induced hip pain, pain-pressure threshold of lateral thigh, and serum creatine kinase compared to the control group (p = 0.006, 0.003, and 0.012, respectively). No statistically significant differences were found between the groups regarding the physical functions.

Conclusions: Lower limb vibration using a vibration roller after total hip arthroplasty was an effective intervention to reduce exercise-induced hip pain and improve serum creatine kinase, but there was no synergistic effect on the physical functions.

背景:振动滚筒是减轻肌肉酸痛和改善受损肌肉功能的有效工具。然而,它在减轻全髋关节置换术后髋部疼痛和改善功能方面的功效尚不明确。我们在一项随机对照临床试验中研究了使用振动滚筒进行下肢振动对全髋关节置换术后髋部疼痛和功能的影响:30名计划接受全髋关节置换术的患者被随机分配到振动组和对照组。振动组患者使用振动滚筒进行下肢振动。对照组患者使用热敷袋进行假治疗。除常规物理治疗外,患者在术后第 1-7 天每天进行 10 分钟的两种干预。主要结果是使用视觉模拟量表测量髋部疼痛强度。次要结果是疼痛-压力阈值、血清肌酸激酶和 C 反应蛋白水平。我们还对身体功能进行了评估,包括哈里斯髋关节评分、髋关节活动范围、肌肉力量、步速和定时起立行走测试。采用分割图设计方差分析法比较了干预措施对各组结果测量的影响:经过一周的干预和三周的随访,与对照组相比,振动组在运动引起的髋关节疼痛、大腿外侧痛压阈值和血清肌酸激酶方面均有显著改善(P = 0.006、0.003 和 0.012)。在身体机能方面,各组之间没有发现明显的统计学差异:结论:全髋关节置换术后使用振动滚筒进行下肢振动是一种有效的干预措施,可减轻运动引起的髋关节疼痛并改善血清肌酸激酶,但对身体机能没有协同作用。
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引用次数: 0
Intraoperative assessment of hindfoot alignment using C-arm fluoroscopy 使用C型臂荧光镜检查术中评估后脚对齐。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.08.014

Background

Hindfoot malalignment can cause various foot and ankle problems. For better surgical performance and correction of hindfoot malalignments, reliable intraoperative determination of hindfoot alignment is essential. However, there is no standard method for the intraoperative assessment of hindfoot alignment. We devised an intraoperative modified Méary posteroanterior (IOPPA) view to assess intraoperative hindfoot alignment. This study aimed to compare this intraoperative method with other radiographic hindfoot alignment measurements.

Methods

Thirty-seven patients (47 feet) with various foot and ankle conditions scheduled to undergo surgery were prospectively recruited. Before surgery, the Saltzman, long axial, and modified Méary views were taken in a controlled and standardized fashion. IOPPA views were obtained under simulated weight bearing conditions using C-arm fluoroscopy in the operating room before surgery. The relationship between the IOPPA view and the three radiographic hindfoot alignments was evaluated using Pearson's correlation.

Results

The mean hindfoot alignment angle was varus 3.50° (CI, varus 1.91 to 5.08) on the Saltzman view, varus 2.00° (CI, varus 0.60 to 3.39) on the long axial view, varus 0.13° (CI, valgus 1.41 to varus 1.67) on the modified Méary view, and varus 1.32° (CI, valgus 0.02 to varus 2.65) on IOPPA view. The IOPPA view and the three other hindfoot alignment views were found to be significantly correlated (r = 0.60 for the Saltzman view, r = 0.50 for the long axial view, r = 0.71 for the modified Méary view, P < .05). The intraobserver ICC (Intraclass Correlation Coefficient) value was 0.974 and interobserver ICC (Intraclass Correlation Coefficient) value was 0.988 for the IOPPA view (P < .001).

Conclusion

There was a statistically significant correlation between the IOPPA view and the other three hindfoot alignment views. We also found that interobserver and intraobserver ICC values were excellent. This study proposes that the IOPPA view can be used as a reliable intraoperative assessment tool for hindfoot alignment.

Level of evidence

Prospective study.

背景:后脚错位会导致各种足部和脚踝问题。为了更好的手术性能和矫正后脚对齐不良,术中可靠的后脚对齐测定至关重要。然而,术中评估后脚对齐没有标准的方法。我们设计了一种术中改良的Méary后前(IOPA)视图来评估术中后脚对齐情况。本研究旨在将这种术中方法与其他放射学后足对齐测量方法进行比较。方法:前瞻性地招募了37名(47英尺)患有各种足部和踝关节疾病并计划接受手术的患者。手术前,Saltzman、长轴和改良的Méary视图是以可控和标准化的方式拍摄的。手术前在手术室使用C型臂荧光镜在模拟承重条件下获得IOPA视图。使用Pearson相关性评估IOPA视图与三种放射学后足对齐之间的关系。结果:Saltzman视野下的平均后足排列角为内翻3.50°(CI,内翻1.91至5.08),长轴视野下的内翻2.00°(CI),改良Méary视野下的外翻0.13°(CI1.41至内翻1.67),IOPA视野下的后足内翻1.32°(CI 0.02至内翻2.65)。IOPA视图和其他三个后足对齐视图被发现显著相关(Saltzman视野为0.60,长轴视野为0.50,改良Méary视野为0.71,P结论:IOPA视野与其他三种后足对齐视野之间存在统计学上显著的相关性。我们还发现观察者间和观察者内ICC值非常好。本研究提出,IOPA视野可作为一种可靠的内窥镜用于后足对齐的ative评估工具。证据水平:前瞻性研究。
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引用次数: 0
Pathophysiology of abnormal compensation ability of the subtalar joint in the varus knee 膝内翻距下关节补偿能力异常的病理生理学。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.09.009

Background

In recent years, the involvement of the compensation ability of the subtalar joint in lower extremity alignment has been reported. We previously showed that hindfoot alignment angle (HAA) is an indicator of compensation ability of the subtalar joint. The abnormal compensation ability of the subtalar joint was defined by the mobility of the subtalar joint, and evaluation of the mobility of the subtalar joint may help to further clarify the pathophysiology of abnormal compensation ability of the subtalar joint. This study was performed to evaluate the mobility of the subtalar joint and clarify the pathophysiology of abnormal compensation ability of the subtalar joint in the varus knee.

Methods

Seventy-two knees of 72 patients aged ≥40 years with varus knee were included in this study. Preoperative radiographs were used for measurement of this study parameters. Based on our previous study, we defined HAA of ≥15.9°as abnormal compensation ability of the subtalar joint. The patients were divided into an abnormal group (A-group) and normal group (N-group). All measurement parameters were compared between the groups, and correlations between the HAA and each measurement parameter were analyzed.

Results

The weight-bearing hindfoot angle (WBHA) (p < 0.001) and non-weight-bearing hindfoot angle (non-WBHA) (p = 0.003), were significantly greater in the A-group than in the N-group. Conversely, the ratio of change in hindfoot alignment (p = 0.006), were significantly smaller in the A-group than in the N-group. The HAA was positively correlated with WBHA (r = 0.66) and non-WBHA (r = 0.43) and negatively correlated with the ratio of change in hindfoot alignment (r = −0.32).

Conclusions

The pathophysiology of abnormal compensation ability of the subtalar joint in the varus knee is thought to involve a state of increased valgus of hindfoot alignment and an inability to move into normal hindfoot alignment.

Level of evidence

Level Ⅲ, retrospective study.

背景:近年来,有报道称距下关节的补偿能力参与下肢对齐。我们之前已经表明,后脚对齐角(HAA)是距下关节补偿能力的指标。距下关节的异常补偿能力是由距下关节活动度定义的,对距下关节运动度的评估可能有助于进一步阐明距下关节异常补偿能力的病理生理学。本研究旨在评估距下关节的活动性,并阐明膝内翻中距下关节异常补偿能力的病理生理学。方法:72例年龄≥40岁膝内翻患者的72个膝关节纳入本研究。术前X线片用于测量本研究的参数。基于我们之前的研究,我们将HAA≥15.9°定义为距下关节的异常补偿能力。将患者分为异常组(A组)和正常组(N组)。比较各组之间的所有测量参数,并分析HAA与每个测量参数之间的相关性。结果:负重后足角(WBHA)(p结论:膝内翻距下关节补偿能力异常的病理生理学被认为涉及后足外翻增加和无法进入正常后足对齐的状态。证据水平:Ⅲ级,回顾性研究。
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引用次数: 0
The influence of COVID-19 epidemic on the number of orthopaedic surgeries in Japan 新冠肺炎疫情对日本整形外科手术数量的影响。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.08.016

Background

There is limited data on the impact of COVID-19 epidemic on the number of orthopaedic surgeries in Japan.

Methods

We conducted a nationwide hospital survey asking for the monthly number of orthopaedic surgeries performed at each facility from January 2019 to June 2021. Those facilities that had performed at least 100 surgeries in 2019 were included for analyses. The facilities were further grouped by prefecture and by hospital characteristics. A brief health economic evaluation was also performed. Risk ratios were compared using univariate analyses with P < 0.05 considered statistically significant.

Results

Questionnaire was sent to 1988 hospitals with 1671 hospitals (84%) responding. The survey data indicated a total number of orthopaedic surgeries decreased in 2020 compared to 2019 (1,061,541 vs 1,119,955 P < 0.01), and also for the first six months of 2021 compared to the same period in 2019 (530,388 vs 550,378 P < 0.01). In 2020, over 50% of all facilities in nearly all of the prefectures saw a decline in surgical procedures.

The risk of incurring more than a 25% decease in the number of surgeries was significantly higher in 2020 for class I designated medical institutions compared to those that were not designated for any types of infectious diseases among the institutions with a tertiary emergency medical center in 2020 (crude risk ratio 2.9: 95% CI 1.2–7.4, p = 0.02) and in 2021 (crude risk ratio 4.7: 95% CI 1 0.9–12.1, p < 0.01).

The estimated total nationwide decrease of revenue were in the range of approximately ¥29.2 to ¥116.8 billion per year for orthopaedic surgeries alone.

Conclusion

There was a statistically significant decrease in the number of orthopaedic surgeries in Japan. The magnitude of the decline varied by prefectures and hospital characteristics, with the greater impact imposed on medical institutions with higher classification functions. The estimated immediate health economic impact was sizable.

背景:关于新冠肺炎疫情对日本整形外科手术数量的影响,数据有限。方法:我们在全国范围内进行了一项医院调查,询问2019年1月至2021年6月每个医院每月进行的整形外科手术数量。那些在2019年进行了至少100次手术的机构被纳入分析范围。这些设施进一步按地区和医院特点进行了分组。还进行了简短的健康经济评估。使用单变量分析将风险比与P进行比较。结果:问卷被发送到1988家医院,1671家医院(84%)做出了回应。调查数据显示,与2019年相比,2020年整形外科手术总数有所下降(1061541 vs 1119955P结论:日本整形外科手术数量在统计上显著下降。下降幅度因县和医院特征而异,对分类功能较高的医疗机构的影响更大。估计的直接健康经济影响相当大。
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引用次数: 0
Reply to letter to the editor by Li et al. 回复 Li 等人致编辑的信
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2024.05.002
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引用次数: 0
Gender differences on preoperative psychologic factors affecting acute postoperative pain in patients with lumbar spinal disorders 影响腰椎疾病患者术后急性疼痛的术前心理因素的性别差异。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.08.019

Background

Psychosexual factors are one of the preoperative factors influencing acute postoperative pain. Because of gender differences in pain, the preoperative factors that influence acute postoperative pain may also differ between males and females. However, there have been no reports on such factors in patients with spinal disorders that focused on gender differences. Therefore, the purpose of this study was to examine the preoperative factors that influence acute postoperative pain, focusing on gender differences.

Methods

The subjects were 75 males and 60 females admitted for surgery for lumbar spinal disorders. Preoperatively, the following were assessed: low back pain using the Numeric Rating Scale (NRS); anxiety and depression using the Japanese version of the Hospital Anxiety and Depression Scale (HADS); catastrophic thinking using the Pain Catastrophizing Scale (PCS); psychiatric problems using the Brief Scale for Psychiatric Problems in Orthopaedic Patients (BS-POP); and neurological assessments. Acute postoperative pain was also assessed using the NRS within 48 h, postoperatively. Based on these data, we analyzed gender differences in preoperative factors affecting acute postoperative pain in patients with lumbar spinal disorders.

Results

Postoperative NRS and preoperative PCS scores were higher in females compared to males. In the males, the coefficient of determination of the multiple regression equation was 0.088, and PCS (β = 0.323, p = 0.015) was extracted as a significant factor. In the females, the coefficient of determination of the multiple regression equation was 0.075, and BS-POP (β = 0.300, p = 0.019) was extracted as a significant factor.

Conclusion

Preoperative factors influencing acute postoperative pain for patients with lumbar spinal disorders vary by gender. It was suggested that males should be screened using PCS. In females, on the other hand, PCS alone is not sufficient for evaluation. It was suggested that evaluation using BS-POP should be considered in addition to PCS.

背景:性心理因素是影响术后急性疼痛的术前因素之一。由于疼痛的性别差异,影响术后急性疼痛的术前因素在男性和女性之间也可能不同。然而,目前还没有关于脊柱疾病患者中此类因素的报告,这些因素主要集中在性别差异上。因此,本研究的目的是检查影响术后急性疼痛的术前因素,重点关注性别差异。方法:受试者为75名男性和60名女性,因腰椎疾病接受手术。术前,评估以下内容:使用数字评定量表(NRS)评估腰痛;使用日本版医院焦虑和抑郁量表(HADS)的焦虑和抑郁;使用疼痛灾难量表的灾难性思维;使用骨科患者精神问题简要量表(BS-POP)的精神问题;以及神经系统评估。术后48小时内使用NRS评估急性术后疼痛。基于这些数据,我们分析了影响腰椎疾病患者术后急性疼痛的术前因素的性别差异。结果:女性术后NRS和术前PCS评分高于男性。在男性中,多元回归方程的决定系数为0.088,PCS(β=0.323,p=0.015)被提取为一个显著因素。在女性中,多元回归方程的决定系数为0.075,提取BS-POP(β=0.300,p=0.019)作为显著因素。结论:影响腰椎疾病患者术后急性疼痛的术前因素因性别而异。有人建议男性应该使用PCS进行筛查。另一方面,在女性中,单独使用PCS不足以进行评估。有人建议,除了PCS外,还应考虑使用BS-POP进行评估。
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引用次数: 0
Incidence and risk of infection in malignant soft tissue tumor resection: Data from the nationwide soft tissue tumor registry 恶性软组织肿瘤切除术中的感染发生率和风险:来自全国软组织肿瘤登记处的数据
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.08.002

Background

Postoperative infection is a devastating complication in limb salvage surgery for malignant soft tissue tumors. The low absolute case numbers of these rare cancers represent a bottleneck for data collection and analysis. The administration of nationwide registry data is a practical option for the accumulation of cases.

Methods

Data on malignant soft tissue tumor resection were extracted from the Bone and Soft Tissue Tumor Registry in Japan. The incidence of postoperative infection and its risk factors were analyzed.

Results

A total of 14,460 cases were included. The incidence of infection was 2.6%. Significant risks for infection were male sex, lower extremity or trunk location, tumor diameter of over 10 cm, trans-compartmental invasion, high grade, autologous bone graft, myocutaneous flap, vascular reconstruction, reconstruction by prosthesis, postoperative radiotherapy, and delayed wound healing.

Conclusions

The incidence was lower than those in the previous studies, perhaps because of less frequent radiotherapy application. Some of the significant risk factors represented local invasiveness of the tumor, suggesting the importance of the preservation of soft tissue for infection prevention. The administration of nationwide registry data was informative for the analysis of infection in malignant soft tissue tumor resection.

背景术后感染是恶性软组织肿瘤肢体救治手术中的一种破坏性并发症。这些罕见癌症的绝对病例数较低,是数据收集和分析的瓶颈。方法从日本骨与软组织肿瘤登记处提取恶性软组织肿瘤切除术的数据。结果 共纳入 14,460 例病例。感染发生率为 2.6%。感染的重要风险因素包括:男性、下肢或躯干位置、肿瘤直径超过 10 厘米、跨腔侵犯、高级别、自体骨移植、肌皮瓣、血管重建、假体重建、术后放疗以及伤口延迟愈合。一些重要的风险因素代表了肿瘤的局部侵袭性,这表明保留软组织对于预防感染非常重要。全国性登记数据的管理为分析恶性软组织肿瘤切除术中的感染提供了信息。
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引用次数: 0
Symptoms of sacral fractures after posterior spinal instrumented fusion: A case series 后路脊柱器械融合术后骶骨骨折的症状:一个病例系列。
IF 1.5 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 DOI: 10.1016/j.jos.2023.09.006

Background

Improvements in spinal fusion devices and techniques have enabled stronger spinal fusion, resulting in excellent clinical outcomes. Nevertheless, complications associated with implants, such as screw misalignment, screw lubrication, cage dislocation, and skin issues, might occur. This study aimed to investigate the characteristics and symptoms of sacral fractures after spinal instrumented fusion.

Methods

This case series retrospectively examined the medical records of eight patients (one man and seven women; mean age: 74 years) diagnosed with sacral fractures after undergoing posterior spinal instrumented fusion from February 2015 to March 2022.

Results

The average number of fusion levels in all patients was 3.5 (range, 1–10). The lowest instrumented vertebrae (LIV) ranged from L5 to the ilium. Sacral fractures were diagnosed at 18.8 (range, 0.5–84) months postoperatively. The average time from consultation to diagnosis was nine days (range, 0–25 days). Two patients had subclinical fractures, two had H-shaped fractures with the LIV at L5, and four had U-shaped fractures, including screw holes. Buttock pain and lower extremity pain, the most commonly reported symptoms, were observed in seven patients each. There were also instances of leg numbness, muscle weakness, and unilateral leg pain that may be related to L5 or S1 radiculopathy. In all patients, leg and buttock pain were worse during movement and in the sitting position, and better while resting and in the supine position. Three patients were treated conservatively, and five were treated with extended fixation to the ilium.

Conclusions

Sacral fractures following posterior spinal fusion can cause radiculopathy and buttock pain. Symptoms are especially severe when instability occurs in the pelvic region, such as during movements or sitting. As atypical radiculopathy may lead to delays in diagnosis, spine surgeons should recognize the symptoms of this condition.

背景:脊柱融合装置和技术的改进使脊柱融合更加牢固,取得了良好的临床效果。然而,可能会出现与植入物相关的并发症,如螺钉错位、螺钉润滑、椎间盘脱位和皮肤问题。本研究旨在探讨脊柱器械融合术后骶骨骨折的特点和症状。方法:本病例系列回顾性分析了2015年2月至2022年3月期间8名患者(1男7女;平均年龄:74岁)在接受后路脊柱融合术后诊断为骶骨骨折的医疗记录。结果:所有患者的平均融合水平为3.5(范围1-10)。最低的器械椎骨(LIV)从L5到髂骨。术后18.8个月(0.5-84个月)诊断为骶部骨折。从咨询到诊断的平均时间为9天(0-25天)。两名患者有亚临床骨折,两名患者在L5处有H型骨折,四名患者有U型骨折,包括螺钉孔。臀部疼痛和下肢疼痛是最常见的症状,各有7名患者出现。还有可能与L5或S1神经根病有关的腿部麻木、肌肉无力和单侧腿部疼痛。在所有患者中,腿部和臀部疼痛在运动和坐姿时更严重,在休息和仰卧位时更好。三名患者接受保守治疗,五名患者接受髂骨延长固定治疗。结论:脊柱融合术后骶部骨折可引起神经根病和臀部疼痛。当骨盆区域出现不稳定时,例如在运动或坐着时,症状尤其严重。由于非典型神经根病可能导致诊断延迟,脊柱外科医生应该认识到这种情况的症状。
{"title":"Symptoms of sacral fractures after posterior spinal instrumented fusion: A case series","authors":"","doi":"10.1016/j.jos.2023.09.006","DOIUrl":"10.1016/j.jos.2023.09.006","url":null,"abstract":"<div><h3>Background</h3><p>Improvements in spinal fusion devices and techniques have enabled stronger spinal fusion, resulting in excellent clinical outcomes. Nevertheless, complications associated with implants, such as screw misalignment, screw lubrication, cage dislocation, and skin issues, might occur. This study aimed to investigate the characteristics and symptoms of sacral fractures after spinal instrumented fusion.</p></div><div><h3>Methods</h3><p>This case series retrospectively examined the medical records of eight patients (one man and seven women; mean age: 74 years) diagnosed with sacral fractures after undergoing posterior spinal instrumented fusion from February 2015 to March 2022.</p></div><div><h3>Results</h3><p><span>The average number of fusion levels in all patients was 3.5 (range, 1–10). The lowest instrumented vertebrae<span> (LIV) ranged from L5 to the ilium. Sacral fractures were diagnosed at 18.8 (range, 0.5–84) months postoperatively. The average time from consultation to diagnosis was nine days (range, 0–25 days). Two patients had subclinical fractures, two had H-shaped fractures with the LIV at L5, and four had U-shaped fractures, including screw holes. Buttock pain and lower extremity pain, the most commonly reported symptoms, were observed in seven patients each. There were also instances of leg numbness, muscle weakness, and unilateral leg pain that may be related to L5 or S1 radiculopathy. In all patients, leg and buttock pain were worse during movement and in the sitting position, and better while resting and in the </span></span>supine position. Three patients were treated conservatively, and five were treated with extended fixation to the ilium.</p></div><div><h3>Conclusions</h3><p>Sacral fractures following posterior spinal fusion can cause radiculopathy and buttock pain. Symptoms are especially severe when instability occurs in the pelvic region, such as during movements or sitting. As atypical radiculopathy may lead to delays in diagnosis, spine surgeons should recognize the symptoms of this condition.</p></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49678786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Orthopaedic Science
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