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ASSOCIATION BETWEEN INSULIN THERAPY ADHERENCE AND GLYCATED HAEMOGLOBIN (HbA1c) AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS ATTENDING A COMMUNITY HEALTH CLINIC 在社区卫生诊所就诊的2型糖尿病患者中,胰岛素治疗依从性与糖化血红蛋白(HbA1c)的关系
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.007
NUR SHAZWANIZA YAHYA, AZLINA AWANG, ROSWATI NORDIN
Insulin therapy is a recommended treatment for diabetes mellitus. Despite knowing insulin is one of the recommended treatments for glycemic control, adherence to insulin therapy still plays the main challenge in achieving good control of glycated haemoglobin (HbA1c). This study aims to determine adherence and compare HbA1c levels before and after six months of insulin therapy among type 2 diabetes patients (T2DM). This cross-sectional study was conducted among 300 participants with T2DM at Sungai Buloh community health clinic, Selangor. A self-administered questionnaire Morisky Insulin Adherence Scale (MIAS), was used to measure the study adherence variable. Data were analysed using a statistical package for the social science (SPSS) version 23. 11 (3.7%) of respondents had good adherence,109 (36.3%) had moderate adherence, and 180 (60%) were poor adherence. The mean HbA1C at baseline is 9.654 mmol/L and reduced to 9.194 mmol/L after six months of insulin therapy. Education shows an association towards adherence level with p-value = 0.004 and significantly found an association between HbA1c and insulin adherence with p < 0.05. The study found that most respondents have poor adherence to insulin therapy. Therefore, essential to highlight adherence issued to achieve good glycaemic control.
胰岛素治疗是糖尿病的推荐治疗方法。尽管知道胰岛素是血糖控制的推荐治疗之一,但坚持胰岛素治疗仍然是实现糖化血红蛋白(HbA1c)良好控制的主要挑战。本研究旨在确定2型糖尿病患者(T2DM)胰岛素治疗前后6个月的依从性并比较HbA1c水平。这项横断面研究是在雪兰莪州Sungai Buloh社区卫生诊所对300名2型糖尿病患者进行的。采用Morisky胰岛素依从性量表(MIAS)来测量研究依从性变量。使用社会科学统计软件包(SPSS)第23版分析数据。依从性良好11例(3.7%),中等依从性109例(36.3%),不良依从性180例(60%)。基线时的平均HbA1C为9.654 mmol/L,胰岛素治疗6个月后降至9.194 mmol/L。教育水平与依从性水平相关(p值= 0.004),HbA1c与胰岛素依从性之间存在显著相关性(p <);0.05. 研究发现,大多数受访者对胰岛素治疗的依从性较差。因此,必须强调坚持发放,以达到良好的血糖控制。
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引用次数: 0
AN ANALYTICAL STUDY OF AWARENESS ABOUT CATARACTS AND VISUAL IMPAIRMENT AMONG UNIVERSITY STUDENTS 大学生白内障及视力损害认知情况分析研究
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.010
NUR SYAWANI SAFFEI, WAN NUR AMIRAH IBRAHIM, PUI JUAN WOI
Cataract is the leading cause of blindness worldwide. This study aimed to assess and compare the awareness levels about cataracts leading to visual impairment between health sciences and non-health sciences university students. A comparative cross-sectional study design was conducted on 432 participants aged 19 to 27 (mean 22.75 ± 1.90), with an equal number of 216 participants from health sciences and non-health sciences students. The data was collected using a questionnaire through an online platform (Google Form). Most respondents (81.5%) had heard about cataracts and knew that cataract incidence increases with age. Most respondents (72.2%) were aware that radiation risks cataracts. 20.1% of the respondents did not aware that cataract surgery is free in government hospitals for certain circumstances. Cataract awareness was statistically higher among health sciences students (1.73 ± 0.13) compared to non-health sciences students (1.52 ± 0.16), t(430) = 13.68, p = 0.001. More than half of the respondents were aware of cataracts and their risk factors, but some still did not know about government hospitals’ free cataract surgery service. High awareness among university students will undoubtedly benefit them and raise awareness of those around them, including their families.
白内障是全世界致盲的主要原因。本研究旨在评估和比较健康科学与非健康科学大学生对白内障导致视力损害的认知水平。采用比较横断面研究设计对432名年龄19 ~ 27岁(平均22.75±1.90)的参与者进行研究,其中216名参与者来自健康科学和非健康科学的学生。数据通过在线平台(Google Form)使用问卷收集。大多数受访者(81.5%)听说过白内障,知道白内障发病率随年龄增长而增加。大多数受访者(72.2%)知道辐射会导致白内障。20.1%的受访者不知道公立医院在某些情况下白内障手术是免费的。健康科学专业学生的白内障知知率(1.73±0.13)高于非健康科学专业学生(1.52±0.16),t(430) = 13.68, p = 0.001。超过一半的受访者了解白内障及其危险因素,但仍有一些人不知道政府医院的免费白内障手术服务。大学生的高意识无疑会使他们受益,并提高他们周围的人,包括他们的家人的意识。
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引用次数: 0
UNFOLDING THE BARRIERS TO TEACHING AND LEARNING WITH TECHNOLOGY AMONG UNDERGRADUATE PRE-SERVICE TEACHERS 揭示本科职前教师的技术教与学障碍
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.005
AHMAD FAHIM ZULKIFLI, AJAU DANIS
The main purpose of this study is to determine the main barriers to learning PE with Coach’s Eye mobile application (TechSmith Corp.) and mobile device. We used an Interpretive Phenomenological Analysis (IPA) approach and found that undergraduate Physical Education (PE) pre-service teachers feared failure when learning sports skills with technology after completing the intervention for six weeks. Despite the intervention group improving their sports skills more than the control group, they also reported a higher tendency of bias when learning sports skills with technology. The participants also highlighted reduced practice time and added responsibilities as a hindrance to this method’s adoption. Our work answers the questions regarding participants’ perceived barriers, technological literacy towards learning sports skills, and motivation to embrace teaching and learning with technology. We also suggested the potential benefits of learning PE with technology for students and educators which warranted future studies to find solutions to mitigate pre-service PE teachers’ concerns about using technology in their teaching sessions. Additionally, future studies are needed to expand our understanding of learning with technology in other sports categories (e.g., invasion, target), the context of learning, and the cognitive ability of various populations.
本研究的主要目的是确定使用Coach’s Eye移动应用程序(TechSmith Corp.)和移动设备学习体育的主要障碍。我们使用解释现象学分析(IPA)方法,发现本科体育教师在完成六周的技术干预后,在学习运动技能时害怕失败。尽管干预组比对照组提高了更多的运动技能,但他们在用科技学习运动技能时也有更高的偏见倾向。参与者还强调了减少练习时间和增加责任是采用这种方法的障碍。我们的工作回答了参与者对学习体育技能的感知障碍、技术素养以及采用技术教学和学习的动机等问题。我们还提出了使用技术学习体育对学生和教育工作者的潜在好处,这保证了未来的研究找到解决方案,以减轻职前体育教师对在教学过程中使用技术的担忧。此外,未来的研究需要扩大我们对其他运动类别(如入侵、目标)、学习背景和不同人群认知能力的理解。
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引用次数: 0
FUNCTIONAL RECOVERY OF DISTAL RADIUS FRACTURE: AN INTERPRETATIVE PHENOMENOLOGICAL ANALYSIS 桡骨远端骨折功能恢复:解释性现象学分析
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.011
NUR ASHYIKIN MD SAZALI, NURUL AFIQ’AH AMAN, MOHAMAD QAYUM MOHAMAD SABRI, MOHD AZAM ABDUL HALIM, JENNI JUDD, AHMAD ZAMIR CHE DAUD
Distal Radius Fracture (DRF) is the most common upper limb fracture, which reduces independence in daily living activities. This study explored the functional recovery of distal radius fracture six months post-injury. We conducted a qualitative study using an Interpretive Phenomenological Analysis (IPA). 11 adults aged 18 and 59 with DRF participated in face-to face, semi-structured, and in-depth interviews recorded digitally. In addition, transcribed recordings were analysed thematically. Four themes emerged from the analysis: (i) I could do or could not do, (ii) How I live my life, (iii) What I feel like, and (iv) Something is wrong with my hand. Following over six months of injury, all participants experienced physical limitations where most participants reported reduced daily activities performance. Consequently, some participants developed adaptive strategies to enhance their daily activities’ ability. DRF also affected their psychological aspects. Overall, DRF affects individuals’ functioning in daily living activities, work and leisure for over six months post-injury. This study highlights that occupational therapists need to maintain or strengthen functional recovery and support individuals with DRF even for over six months post-injury.
桡骨远端骨折(DRF)是最常见的上肢骨折,它降低了日常生活活动的独立性。本研究探讨桡骨远端骨折损伤后6个月的功能恢复情况。我们使用解释现象学分析(IPA)进行了定性研究。11名年龄在18岁到59岁之间的DRF患者参加了面对面、半结构化和深度的数字化访谈。此外,还对转录的录音进行了专题分析。分析中出现了四个主题:(1)我能做或不能做;(2)我如何生活;(3)我的感觉如何;(4)我的手出了问题。在受伤六个多月后,所有参与者都经历了身体限制,大多数参与者报告日常活动表现下降。因此,一些参与者制定了适应性策略来提高他们的日常活动能力。DRF也影响到他们的心理方面。总体而言,DRF在受伤后的6个月内会影响个人的日常生活活动、工作和休闲功能。这项研究强调,职业治疗师需要维持或加强功能恢复,并支持患有DRF的个体,即使在受伤后超过6个月。
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引用次数: 0
NUTRIENT MANAGEMENT FOR RUBBER PLANTATION USING GOAL PROGRAMMING 利用目标规划进行橡胶林养分管理
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.001
NURIDAWATI BAHAROM, NURUL AIN MOHD RAZALI
: Farm management must have proper planning on the resources such as fertiliser, labour, water and pesticide. Fertiliser provides healthy growth to the plant. It is one of the important resources the farm needs. Thus, the usage and allocation of fertilisers must be managed wisely to avoid wastage that incurs costs. This paper presents a case study which focuses on the nutrient management of rubber plantations. The main objective is to minimise the cost of chemical fertilisers used to plant rubber. Besides, the sub-objectives are to determine the best weight combination for fertilisers and calculate the mass per hectare of Nitrogen, Phosphorus, and Potassium needed for the rubber trees. The goal programming approach has been applied to solve the problem. In the model formulation, there are seven decision variables representing chemical fertilisers, while the constraints are the cost of chemical fertilisers and the requirement of the upper and the lower limit of nutrients in the chemical fertilisers. Results indicate that this method can meet all the goals expected. In conclusion, this study shows that goal programming is suitable for modelling plant input, cost and constraint of rubber farm management.
农场管理必须对诸如肥料、劳动力、水和农药等资源进行适当的规划。肥料使植物健康生长。它是农场需要的重要资源之一。因此,必须明智地管理化肥的使用和分配,以避免产生成本的浪费。本文以橡胶林的营养管理为例进行了研究。主要目标是尽量减少种植橡胶所用化肥的成本。此外,子目标是确定肥料的最佳重量组合,并计算橡胶树每公顷所需的氮、磷、钾的质量。本文采用目标规划方法对该问题进行了求解。在模型公式中,有7个决策变量代表化肥,约束条件是化肥的成本和化肥中养分的上下限要求。结果表明,该方法可以达到预期的目标。研究结果表明,目标规划方法适用于模拟橡胶场管理的工厂投入、成本和约束。
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引用次数: 0
ANTECEDENTS OF ORGANIC FOOD PURCHASE INTENTION: DOES IT MODERATE BY THE RECEPTIVITY TO GREEN COMMUNICATION? 有机食品购买意愿的前因:是否受绿色传播接受度的调节?
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.004
MUHAMMAD SAFUAN ABDUL LATIP, SITI AISYAH TUMIN, RACHEL YUEN MAY YONG
Given the global environmental degradation due to conventional food consumption and demand, sustainable food consumption (organic food) counters the deterioration by increasing consumers’ sustainable food consumption. As organic food development in Malaysia remains in its infancy as a niche market, research on green marketing with localised applications remains scarce and does not significantly catalyse organic food demand. The study investigates the consumers’ attitudes, perceived social pressure, autonomy, and receptivity to green communication toward organic food purchase intention. The study applied a causal analysis where a quantitative method was employed. Purposive sampling was employed in the study, where primary data was used for analysis through an online survey. The survey employed five Likert scale measurements where data were collected in Malaysia, and 268 valid responses were obtained. The data were analysed using SPSS and AMOS software. The finding revealed a significant influence of personal attitude, perceived autonomy, and receptivity to green communication on organic food purchase intention. Perceived social pressure did not indicate a statistically significant relationship towards organic food purchase intention. Receptivity to green communication was found to be statistically insignificant as a moderator. Stakeholders and organic food producers may benefit from the study’s detailed analysis of the market’s current state to better predict its growth and ensure the industry’s long-term viability.
鉴于传统食品消费和需求导致的全球环境恶化,可持续食品消费(有机食品)通过增加消费者的可持续食品消费来应对恶化。由于马来西亚的有机食品发展作为一个利基市场仍处于起步阶段,对本地化应用的绿色营销的研究仍然很少,并且没有显著促进有机食品的需求。本研究考察消费者对有机食品购买意向的态度、感知到的社会压力、自主性、绿色传播接受度。本研究采用定量方法进行因果分析。本研究采用目的性抽样的方法,通过在线调查的方式对原始数据进行分析。该调查采用五种李克特量表测量,在马来西亚收集数据,并获得268个有效答复。采用SPSS和AMOS软件对数据进行分析。研究发现,个人态度、自主性感知和绿色传播接受度对有机食品购买意愿有显著影响。感知到的社会压力对有机食品购买意愿没有统计学上的显著关系。对绿色沟通的接受度被发现在统计上不显著。利益相关者和有机食品生产商可能会受益于该研究对市场现状的详细分析,以更好地预测其增长,并确保该行业的长期生存能力。
{"title":"ANTECEDENTS OF ORGANIC FOOD PURCHASE INTENTION: DOES IT MODERATE BY THE RECEPTIVITY TO GREEN COMMUNICATION?","authors":"MUHAMMAD SAFUAN ABDUL LATIP, SITI AISYAH TUMIN, RACHEL YUEN MAY YONG","doi":"10.46754/jssm.2023.06.004","DOIUrl":"https://doi.org/10.46754/jssm.2023.06.004","url":null,"abstract":"Given the global environmental degradation due to conventional food consumption and demand, sustainable food consumption (organic food) counters the deterioration by increasing consumers’ sustainable food consumption. As organic food development in Malaysia remains in its infancy as a niche market, research on green marketing with localised applications remains scarce and does not significantly catalyse organic food demand. The study investigates the consumers’ attitudes, perceived social pressure, autonomy, and receptivity to green communication toward organic food purchase intention. The study applied a causal analysis where a quantitative method was employed. Purposive sampling was employed in the study, where primary data was used for analysis through an online survey. The survey employed five Likert scale measurements where data were collected in Malaysia, and 268 valid responses were obtained. The data were analysed using SPSS and AMOS software. The finding revealed a significant influence of personal attitude, perceived autonomy, and receptivity to green communication on organic food purchase intention. Perceived social pressure did not indicate a statistically significant relationship towards organic food purchase intention. Receptivity to green communication was found to be statistically insignificant as a moderator. Stakeholders and organic food producers may benefit from the study’s detailed analysis of the market’s current state to better predict its growth and ensure the industry’s long-term viability.","PeriodicalId":17041,"journal":{"name":"JOURNAL OF SUSTAINABILITY SCIENCE AND MANAGEMENT","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136366430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
SOCIO-SPATIAL TRANSFORMATION: PERSPECTIVE OF MANAGEMENT OF COASTAL AREA DEVELOPMENT BASED ON OPTIMISING THE ROLE OF LOCAL COMMUNITIES IN MANADO CITY, INDONESIA 社会空间转型:基于优化印尼万鸦老市当地社区作用的沿海地区发展管理视角
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.003
HENDRIK SURIANDJO, BATARA SURYA, DARMAWAN SALMAN, SYAMSUL BAHRI, MURSHAL MANAF, ANDI MUHIBUDDIN, ANANTO YUDONO, SYAFRI SYAFRI
Socio-spatial transformation of urban architecture is a process that changes the elements of urban architecture and its formers. Development in coastal areas always impacts local communities on the coast. Sometimes they experience a process of change that requires them to adapt and even integrate situationally. This study aims to describe the socio-spatial transformation reality of contemporary urban architectural elements through a phased dynamic from the perspective of local communities in urban coastal areas. The method is conducted by qualitative research method. This is a single case study to identify a specific case used to study real-life cases of the initiation of adaptation and integration of local communities. Data were obtained through participant observation, documentation and inductive in-depth interviews and focus group discussions that focused on descriptive theme analysis to understand the process of socio-spatial transformation of urban architectural elements in urban coastal local communities. The result of this study is a cycle of socio-spatial transformation of urban architectural elements is formed, consisting of (1) the natural, normal phase; (2) the adaptation initiation phase; and (3) the integration phase.
城市建筑的社会空间转型是一个改变城市建筑及其构成要素的过程。沿海地区的发展总是影响着沿海地区的当地社区。有时,他们会经历一个需要他们适应甚至融入情境的变化过程。本研究旨在从城市沿海地区当地社区的角度,通过阶段性动态描述当代城市建筑元素的社会空间转型现实。方法采用定性研究方法。这是一项单一案例研究,旨在确定一个具体案例,用于研究启动当地社区适应和融合的现实案例。通过参与式观察、文献记录、归纳式深度访谈和焦点小组讨论等方式获取数据,以描述性主题分析为重点,了解城市沿海当地社区城市建筑元素的社会空间转型过程。本研究的结果是形成了一个循环的社会空间转换的城市建筑要素,包括(1)自然、正常阶段;(2)适应启动阶段;(3)集成阶段。
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引用次数: 0
NO CHANGES IN THE ACCOMMODATIVE STIMULUS-RESPONSE CURVE BUT VARIED LAG OF ACCOMMODATION AFTER A 30-MIN ELECTRONIC NEAR TASK UNDER FOUR DIFFERENT LIGHTING CONDITIONS AMONG MYOPIC YOUNG ADULTS 四种不同光照条件下30分钟电子近距离任务后,青年人的调节刺激-反应曲线无变化,但调节滞后有所变化
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.002
AI-HONG CHEN, FAZRIN MAZLAN, NIALL STRANG
The prevalence of myopia is increasing worldwide, mainly in Asian countries. Light-emitting Diodes (LED) and low light levels used for homework after school was thought to contribute to myopia development. This study explored how near work and lighting affect the accommodation response. 30 myopic young Malay adults (18-23 years old) were recruited. The ASRC was measured after performing a 30-min near the electronic task at 20 cm using a binocular open-field autorefraction (Grand Seiko, Shin-Nippon) at 6.0 m, 1.0 m, 0.5 m, 0.33 m, 0.25 m, and 0.20 m under four different lighting conditions (Fluorescent 6500K, Fluorescent 3000K, LED 6500K, LED 3000K). A significant flattening in the ASRC gradient was noted when comparing pre and post-measures following the near-vision task for all lighting conditions (p < 0.01). ASRC gradient differences were not affected by lighting conditions (One-way repeated measure ANOVA F (3,87) = 0.84, p > 0.05). ASRC gradient was affected only after 30 minutes of near work F (3,87) = 0.049, p < 0.05). The increment in the accommodative inaccuracy was apparent following prolonged close work. Types of light were not imperative. This information on short-term exposure can be useful for interior light choice of buildings. The effect of long-term exposure requires further investigation.
近视的发病率在世界范围内呈上升趋势,主要在亚洲国家。人们认为,放学后做作业时使用发光二极管(LED)和低光水平会导致近视的发生。这项研究探讨了近距离工作和照明如何影响适应反应。招募30名近视的马来族青年成人(18-23岁)。在4种不同的照明条件(荧光灯6500K、荧光灯3000K、LED 6500K、LED 3000K)下,在20 cm的电子任务附近,使用双视野自折射(Grand Seiko, Shin-Nippon)在6.0 m、1.0 m、0.5 m、0.33 m、0.25 m和0.20 m处测量ASRC 30分钟。在所有照明条件下,在比较近视力任务前后的测量结果时,ASRC梯度明显变平(p <0.01)。ASRC梯度差异不受光照条件的影响(单因素重复测量方差分析F (3,87) = 0.84, p >0.05)。ASRC梯度仅在近工作30分钟后受到影响F (3,87) = 0.049, p <0.05)。在长时间的密切工作后,调节误差的增加是明显的。光的种类并不是必须的。这些关于短期暴露的信息对于建筑物内部光线的选择是有用的。长期接触的影响需要进一步调查。
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引用次数: 0
EFFECT OF LECTINS FROM SELECTED MALAYSIAN LOCAL FRUITS ON HUMAN BLOOD GROUP ANTIGENS 精选马来西亚当地水果凝集素对人血型抗原的影响
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.008
NUR AMIRA DZULKIPLI, ZAINOL HAIDA, TENGKU SHAHRUL ANUAR, EVANA KAMARUDIN
Many individuals nowadays enjoy eating various types of local fruits without realising the impact of the fruits on blood group antigens. The fruit lectin can cause damage to the mucosal surface in the gut when the lectin is incompatible with blood group antigens. Therefore, the present study aims to determine the in vitro plant lectins reaction from the extraction of Artocarpus heterophyllus Lam. (Jackfruit), Artocarpus altilis (Parkinson ex F.A.Zorn), Fosberg (Breadfruit), Carica papaya (Papaya), Manilkara zapota (L.) P. Royen (Sapota) and Salacca zalacca (Gaertn.) Voss (Salak) with specific human blood group antigens. The local fruit extract was tested with human blood groups A and B for hemagglutination assay. The agglutination titer of the hemagglutination assay results was then evaluated. The total of 3+ reactions for jackfruit was 11%, salak (4%) and papaya(6%) for both blood groups. The breadfruit shows the highest titer reaction, 19% against A and 16% against B. In comparison, 19% was against A for sapota but only 4% towards group B. The highest titer value of erythrocytes by crude lectins of selected local fruits on blood groups A and B was given by extraction of sapota while for blood group B on papaya. This discovery proves that plant lectins from five varieties of local fruits react with blood group antigens and that comparable interactions may occur at the mucosal surface of the gut in susceptible individuals, causing significant inflammation, swelling, and ulceration. The mechanism and effect of fruit lectin on human blood types should be investigated further.
现在许多人喜欢吃各种各样的当地水果,却没有意识到水果对血型抗原的影响。当水果凝集素与血型抗原不相容时,会对肠道粘膜表面造成损伤。因此,本研究的目的是确定从太子参中提取的植物凝集素的体外反应。(Jackfruit), Artocarpus altilis (Parkinson ex F.A.Zorn), Fosberg(面包果),Carica papaya(木瓜),Manilkara zapota (L.)P. Royen (Sapota)和Salacca zalacca (Gaertn)沃斯(萨拉克)有特定的人类血型抗原。用人血A、B组进行血凝试验。然后评价血凝试验结果的凝集效价。在两种血型中,菠萝蜜(11%)、沙拉(4%)和木瓜(6%)的3+反应总数为11%。其中,面包果对A的效价最高,分别为19%和16%。对A的效价为19%,对B的效价仅为4%。对A、B血型的红细胞效价最高的是皂角提取的当地水果粗凝集素,而对B血型的红细胞效价最高的是木瓜。这一发现证明,来自五种当地水果的植物凝集素与血型抗原发生反应,并且在易感个体的肠道粘膜表面可能发生类似的相互作用,引起明显的炎症、肿胀和溃疡。水果凝集素对人血型的作用机制有待进一步研究。
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引用次数: 0
SUSTAINABLE BIOREMEDIATION OF ACETAMINOPHEN USING BACTERIA: A CRITICAL REVIEW 利用细菌进行对乙酰氨基酚的可持续生物修复:综述
Q3 Social Sciences Pub Date : 2023-06-30 DOI: 10.46754/jssm.2023.06.013
NUR K'SYA KARLINA GEORGE HAIKAL, IZZATIL AINA RAZALI, WAN NURHAYATI WAN HANAFI, ALMANDO GERALDI, NI’MATUZAHROH NI’MATUZAHROH, FATIMAH FATIMAH, CHIA CHAY TAY
Acetaminophen is a common antipyretic and analgesic pharmaceutical contaminant and has become one of the most emerging contaminants in the environment. Bioremediation is the suitable method to degrade acetaminophen as it is sustainable, mimics nature and is low-cost. The bioremediation of acetaminophen is performed by identifying the bacterial characteristics and the source of the bacteria involved in the degradation of acetaminophen. Based on this review study, gram-negative bacteria showed the highest efficiency in degrading acetaminophen by Pseudomonas aeruginosa strain HJ1012 and Cupriavidus necator with an efficiency of 99% and 100%, respectively. In addition, synergistic or antagonistic interaction among bacteria in mixed culture is a gap of study. The findings from the previous study showed that the optimum conditions are pH 7.0, temperature ranges between 30–40°C, and a poor culture medium of minimal salt solution. Furthermore, the study sheds light on enzyme involvement and characterisation of acetaminophen degradation pathways toward less harmful intermediates are addressed in order to achieve sustainable development goals through environmental security and health safety. These identified research gaps offer fundamental knowledge and shed insight into upcoming mechanism and application studies.
对乙酰氨基酚是一种常见的解热镇痛药物污染物,已成为环境中最新兴的污染物之一。生物修复是降解对乙酰氨基酚的合适方法,具有可持续性、模拟自然、低成本等优点。对乙酰氨基酚的生物修复是通过鉴定细菌特征和参与对乙酰氨基酚降解的细菌来源来进行的。本综述发现,革兰氏阴性菌对对乙酰氨基酚的降解效率最高的菌株为铜绿假单胞菌HJ1012和necator铜单胞菌,降解效率分别为99%和100%。此外,混合培养中细菌之间的协同或拮抗相互作用是研究的空白。前期研究结果表明,最佳条件为pH 7.0,温度范围30-40°C,低盐培养基。此外,该研究阐明了酶的参与和对乙酰氨基酚降解途径的特征,以达到危害较小的中间体,从而通过环境安全和健康安全实现可持续发展目标。这些确定的研究差距提供了基础知识,并为即将到来的机制和应用研究提供了见解。
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引用次数: 0
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