Pub Date : 2019-09-28DOI: 10.23937/2643-3966/1710023
F. Ribeiro, Braile-Sternieri Maria Christiane Valéria Braga, M. Migliorini, Sternieri Giovanni Braile, Sabino Sofia Braile, Queiroz Cibele Olegário Vianna, Sbardellini Bethina Canaroli, Verdi Luiza Braile, Filho Idiberto José Zotarelli, Braile Domingo Marcolino
Pub Date : 2019-08-28DOI: 10.23937/2643-3966/1710022
N MüllerPhilippe, Jost Christine H Attenhofer, B. Osmund, Naegeli Barbara, S. Edwin, Levis Pierre, Seifert Burkhardt, Maurer Dominik, S. Christoph, Franzen Olaf, Amann Franz Wolfgang
Pub Date : 2019-08-26DOI: 10.23937/2643-3966/1710021
O. Alawni, A. Almusaad, W. Eyaid
{"title":"Case Report: A 13 Years Old Boy with Danon Disease, and Intellectual Disability","authors":"O. Alawni, A. Almusaad, W. Eyaid","doi":"10.23937/2643-3966/1710021","DOIUrl":"https://doi.org/10.23937/2643-3966/1710021","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133266105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-30DOI: 10.23937/IACVD-2017/1710014
Kuate Liliane Mfeukeu, Ondoa Helene Ornella Bongha, Katte Jean-Claude, Tankeu Aurel Tiakouang, Bokam Mireille Claudia Abeng, Bimbai Andre Michel, J. Musa, Nganou-Gnindjio Chris Nadège, Dehayem Mesmin Yefou, K. Folefack, M. J. Claude, Kengne Andre Pascal, Sobngwi Eugène
Background: Renin-angiotensin system antagonists are the mainstays of blood pressure (BP) lowering strategies in people with diabetes. Perindopril a long half-life Angiotensin Converting Enzyme (ACE) inhibitor offers the advantage of a single daily dose, usually empirically taken in the morning. We therefore aimed to assess the influence of time of administration on the effect of Perindopril on circadian BP in type 2 diabetes (T2D) individuals with previously untreated stage 1 hypertension. Methods: Twenty T2D patients (9 being women) with a mean age of 58.7 years, newly diagnosed with stage 1 hypertension, were randomly allocated to receive perindopril 10 mg/day as monotherapy either in the morning or in the evening for 28 days, with crossover without washout period on day 29th and additional 28 days follow-up. A 24hour ambulatory BP monitoring (ABPM) was performed at baseline, days 28 and 56. This study was retrospectively registered having a trial registration: ClinicalTrials.gov Identifier: NCT03393715. January 8, 2018. Results: Median diagnosed duration of diabetes was 2.0 years. At baseline, mean 24-hour systolic and diastolic BP were 137.0 mmHg and 84.5 mmHg, and mean albumin/ creatinine ratio (ACR) was 132.6 mg/g. There was no difference in the 24-hour systolic blood pressure pattern between the patients on morning perindopril and patients on evening perindopril (p = 0.61). The chronotherapeutic scheme did not influence neither ACR (p = 0.58) nor uric acid level (p = 0.32). However, the administration of 10 mg Perindopril lowered the ACR in both treatment allocation sequences; with an overall treatment effect of -41.7 (95% CI: -92.6 to 9.2) mg/g. Conclusions: The morning administration of perindopril did not prove to be superior to night time regimen for BP control in this group of sub-Saharan type 2 diabetes patients with stage 1 hypertension. However, the administration of perindopril seems to lower the ACR which is suggestive of the reno-protective effect of ACE inhibitors in patients presenting with hypertension and type 2 diabetes. RESEARCH ARTiCLE
{"title":"Effects of Morning versus Evening Administration of Perindopril on the Circadian Control of Blood Pressure in Cameroonian Type 2 Diabetes Individuals: A Crossover Randomized Trial","authors":"Kuate Liliane Mfeukeu, Ondoa Helene Ornella Bongha, Katte Jean-Claude, Tankeu Aurel Tiakouang, Bokam Mireille Claudia Abeng, Bimbai Andre Michel, J. Musa, Nganou-Gnindjio Chris Nadège, Dehayem Mesmin Yefou, K. Folefack, M. J. Claude, Kengne Andre Pascal, Sobngwi Eugène","doi":"10.23937/IACVD-2017/1710014","DOIUrl":"https://doi.org/10.23937/IACVD-2017/1710014","url":null,"abstract":"Background: Renin-angiotensin system antagonists are the mainstays of blood pressure (BP) lowering strategies in people with diabetes. Perindopril a long half-life Angiotensin Converting Enzyme (ACE) inhibitor offers the advantage of a single daily dose, usually empirically taken in the morning. We therefore aimed to assess the influence of time of administration on the effect of Perindopril on circadian BP in type 2 diabetes (T2D) individuals with previously untreated stage 1 hypertension. Methods: Twenty T2D patients (9 being women) with a mean age of 58.7 years, newly diagnosed with stage 1 hypertension, were randomly allocated to receive perindopril 10 mg/day as monotherapy either in the morning or in the evening for 28 days, with crossover without washout period on day 29th and additional 28 days follow-up. A 24hour ambulatory BP monitoring (ABPM) was performed at baseline, days 28 and 56. This study was retrospectively registered having a trial registration: ClinicalTrials.gov Identifier: NCT03393715. January 8, 2018. Results: Median diagnosed duration of diabetes was 2.0 years. At baseline, mean 24-hour systolic and diastolic BP were 137.0 mmHg and 84.5 mmHg, and mean albumin/ creatinine ratio (ACR) was 132.6 mg/g. There was no difference in the 24-hour systolic blood pressure pattern between the patients on morning perindopril and patients on evening perindopril (p = 0.61). The chronotherapeutic scheme did not influence neither ACR (p = 0.58) nor uric acid level (p = 0.32). However, the administration of 10 mg Perindopril lowered the ACR in both treatment allocation sequences; with an overall treatment effect of -41.7 (95% CI: -92.6 to 9.2) mg/g. Conclusions: The morning administration of perindopril did not prove to be superior to night time regimen for BP control in this group of sub-Saharan type 2 diabetes patients with stage 1 hypertension. However, the administration of perindopril seems to lower the ACR which is suggestive of the reno-protective effect of ACE inhibitors in patients presenting with hypertension and type 2 diabetes. RESEARCH ARTiCLE","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126992703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
diagnosed Bartter syndrome. In her history, it was learned that she was hospitalized for sepsis, pneumonia and was cannulated with the umbilical venous catheter. Seventh day of the birth, echocardiography performed due to murmur had no additional pathology other than foramen ovale. In her physical examination, the heart rate was 136/bpm, respiratory rate was 28/ min, blood pressure was 85/52 mmHg, and peripheral oxygen saturation was 94% by pulse oximetry. The patient had no dyspnea. There was a 2/6 systolic murmur over mesocardiac area. Complete blood count revealed leucocyte: 14.000/mm 3 , hemoglobin: 11 g/dl, platelet: 280000/mm 3 . Hepatic and renal function tests, C reactive Abstract Central venous catheters are commonly used in clinical practice. Right atrial thrombosis is a relatively common complication associated with indwelling catheter use. Thrombosis can be in different locations and forms within vascular and intracardiac structures. Echocardiographic images may mimic some anatomic and pathologic variants. We describe a case of a two-months-old girl with a thrombus which cor triatriatum dexter-like appearance in the right atrium due to the central venous catheter.
{"title":"An Unusual Thrombosis Mimicking Cor Triatriatum Dextra","authors":"Surucu Murat, Gursu Hazım Alper, Çetinİbrahim İlker","doi":"10.23937/IACVD-2017/1710015","DOIUrl":"https://doi.org/10.23937/IACVD-2017/1710015","url":null,"abstract":"diagnosed Bartter syndrome. In her history, it was learned that she was hospitalized for sepsis, pneumonia and was cannulated with the umbilical venous catheter. Seventh day of the birth, echocardiography performed due to murmur had no additional pathology other than foramen ovale. In her physical examination, the heart rate was 136/bpm, respiratory rate was 28/ min, blood pressure was 85/52 mmHg, and peripheral oxygen saturation was 94% by pulse oximetry. The patient had no dyspnea. There was a 2/6 systolic murmur over mesocardiac area. Complete blood count revealed leucocyte: 14.000/mm 3 , hemoglobin: 11 g/dl, platelet: 280000/mm 3 . Hepatic and renal function tests, C reactive Abstract Central venous catheters are commonly used in clinical practice. Right atrial thrombosis is a relatively common complication associated with indwelling catheter use. Thrombosis can be in different locations and forms within vascular and intracardiac structures. Echocardiographic images may mimic some anatomic and pathologic variants. We describe a case of a two-months-old girl with a thrombus which cor triatriatum dexter-like appearance in the right atrium due to the central venous catheter.","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"2019 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125640147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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