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Bilateral circumscribed posterior keratoconus. 双侧限定后圆锥角膜。
D Q Chan

Background: Posterior keratoconus is a rare corneal disorder characterized by a diffuse or localized protrusion of the posterior corneal surface into a thinning stroma. It is believed to be a congenital, nonprogressive condition.

Case report: A case of bilateral circumscribed posterior keratoconus is presented. Diagnostic ocular signs include localized protrusion of the posterior corneal surface, normal anterior corneal surface, stromal thinning, and endothelial changes. However, anterior corneal contour reveals progressive steepening in this case.

Conclusion: Posterior keratoconus is an unusual corneal anomaly with subtle clinical features. Recognition of these signs is essential in the diagnostic and management processes.

背景:后圆锥角膜是一种罕见的角膜疾病,其特征是角膜后表面弥漫性或局域性突出,形成变薄的间质。它被认为是一种先天性的非进行性疾病。病例报告:报告一例双侧后圆锥角膜局限。诊断性眼部征象包括角膜后表面局部突出、角膜前表面正常、间质变薄和内皮改变。然而,在本例中,角膜前轮廓显示渐进性变陡。结论:后圆锥角膜是一种罕见的角膜异常,临床特征微妙。在诊断和管理过程中,识别这些体征是必不可少的。
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引用次数: 0
Growing older, with grace and dignity. 带着优雅和尊严慢慢变老。
P B Freeman
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引用次数: 0
Fundus albipunctatus and other flecked retina syndromes. 白点眼底及其他斑点性视网膜综合征。
M F Flynn, D Bohnert

Background: Several ophthalmic conditions manifest a flecked retina. Developing an understanding of their clinical presentations will enable the practitioner to most appropriately manage these conditions.

Case report: A 27-year-old Middle Eastern woman manifested flecked retinas and nyctalopia. She had been given a diagnosis of retinitis punctata albescens, an inherited, progressive, night blindness; however, the medical history and clinical findings were not consistent with this disorder. Rather, they were consistent with fundus albipunctatus, an autosomal recessive, stationary, night blindness. The clinical presentation of fundus albipunctatus is characterized by discrete, white dots at the level of the retinal pigment epithelium and stable night blindness. A prolonged time for dark adaptation is required to produce normal amplitude electroretinograms in fundus albipunctatus as the result of a delay in the regeneration of rhodopsin. An electroretinogram administered after a prolonged dark adaptation time confirmed the diagnosis of stationary night blindness.

Conclusion: In order to ensure an accurate diagnosis for fundus albipunctatus, it is important to be aware of the clinical characteristics and appropriate electroretinogram protocol for this disorder.

背景:一些眼科疾病表现为视网膜斑点。了解他们的临床表现将使医生能够最恰当地处理这些情况。病例报告:一名27岁的中东女性表现为视网膜斑点和夜盲症。她被诊断为白斑视网膜炎,一种遗传性进行性夜盲症;然而,病史和临床表现与这种疾病不一致。相反,他们符合眼底白斑,一种常染色体隐性,静止,夜盲症。白点眼底的临床表现为视网膜色素上皮水平的离散白点和稳定的夜盲症。由于视紫红质再生的延迟,长时间的暗适应需要在白点眼底产生正常振幅的视网膜电图。在长时间的黑暗适应时间后进行视网膜电图检查,证实了静止性夜盲症的诊断。结论:了解白点眼底的临床特点,选择合适的视网膜电图治疗方案,是准确诊断白点眼底的重要手段。
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引用次数: 0
Back-to-school programs that work. 返校计划是有效的。
G M Bailey
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引用次数: 0
Relationship between age and presbyopic addition using a sample of 3,645 examinations from a single private practice. 年龄与老花眼之间的关系,使用来自单个私人诊所的3,645个检查样本。
P A Blystone

Background: This study uses information collected in a private optometric practice to describe the relationship between age and the add power needed to correct presbyopia.

Methods: Computer-assisted data analysis with a database management program, Q&A, and Microsoft Excel was used to assess the relationship between age and presbyopic addition. Data collected from 3,645 examinations by one practitioner in a single private practice--over a period of approximately 23 years--were entered into the database. The patient base was primarily white and about equally divided between the sexes. The practitioner generally used the fused cross cylinder for the tentative presbyopic addition and refined this by patient preference and best visual acuity at near, all using a carefully determined near working distance.

Results: The presbyopic addition increased rapidly in patients from ages 40 to 50 years, the rate at age 40 being about 0.22 diopters per year and the average rate during the 40- to 50-year-old decade being about 0.12 diopters per year, or approximately 0.25 diopters every 2 years. After the patient reaches 50 years of age, the presbyopic addition increased more slowly, at the rate of approximately 0.03 diopters per year--or approximately 0.25 diopters in 8 years.

Conclusions: Quantitative data taken from more than 3,600 refractions showed a nearly parabolic relationship between age and presbyopic addition from approximately the age of 40 to 75 years.

背景:本研究使用在私人验光实践中收集的信息来描述年龄与矫正老花眼所需的额外力量之间的关系。方法:采用数据库管理程序、问答和Microsoft Excel进行计算机辅助数据分析,评价年龄与老花眼的关系。在大约23年的时间里,从一名医生在一家私人诊所的3645次检查中收集的数据被输入数据库。患者基础主要是白人,男女比例大致相等。医生通常使用融合的交叉柱体作为试探性老花眼的补充,并根据患者的偏好和近距离的最佳视力进行改进,所有这些都使用仔细确定的近工作距离。结果:40 ~ 50岁患者的老花眼增加迅速,40岁时的速度约为每年0.22屈光度,40 ~ 50岁的平均速度约为每年0.12屈光度,约为每2年0.25屈光度。患者50岁后,老花眼的增加速度较慢,每年约为0.03屈光度,8年约为0.25屈光度。结论:从3600多例屈光试验中获得的定量数据显示,年龄和老花眼之间的关系从大约40岁到75岁几乎呈抛物线关系。
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引用次数: 0
PEP strategies. PEP的策略。
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引用次数: 0
Differential diagnosis of common etiologies of photopsia. 常见致光原因的鉴别诊断。
J F Amos

Background: Photopsia is a relatively common symptom reported by patients in primary eye care settings. Although there are many possible etiologies, photopsia (light flashes) is usually associated with one of the following: (1) posterior vitreous detachment, (2) migraine with aura, (3) migraine aura without headache, and (4) retinal break or detachment. Each of these clinical conditions has symptoms and physical findings that will usually render the diagnosis apparent.

Methods: It is important from a clinicolegal standpoint that specific procedures be performed to differentially diagnose the responsible condition and deliver appropriate follow-up care.

背景:失光是一种相对常见的症状报告的患者在初级眼科保健设置。虽然有许多可能的病因,但光失(闪光)通常与以下之一有关:(1)玻璃体后脱离,(2)先兆偏头痛,(3)偏头痛先兆不头痛,(4)视网膜断裂或脱离。每一种临床情况都有症状和身体检查结果,通常会使诊断变得明显。方法:从临床法律的角度来看,重要的是要执行具体的程序来鉴别诊断责任条件和提供适当的随访护理。
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引用次数: 0
One-year results from the phase III investigation of the KeraVision Intacs. KeraVision Intacs的III期研究结果。
M D Twa, P M Karpecki, B J King, S H Linn, D S Durrie, D J Schanzlin

Background: Limitations of the surgical correction for myopia include inaccuracy, instability, treatment of the central optical zone, and lack of reversibility. KeraVision Intacs offer an alternative that addresses these shortcomings.

Methods: We present 1 year of follow-up information on 95 subjects enrolled in the United States Food and Drug Administration Phase III clinical trials.

Results: At 1 year, 99% of patients (89 of 90) had 20/40 uncorrected vision or better. Ninety-two percent of eyes (83 of 90) were within 1.00 D of intended correction and 76% of eyes (68 of 90) were within 0.50 D of intended correction. Stability was achieved at 3 months, with 96% of subjects (86 of 90) having less than 1.00 D of change from their previous examination. In a substudy, 89% eyes (58 of 65) varied within +/- 0.50 D over the course of a day. Corneal curvature changed as predicted, resulting in a prolate aspheric shape within the central optical zone. Most complications or adverse events experienced were managed with additional medication or surgical intervention, resulting in a favorable outcome for subjects.

Conclusions: KeraVision Intacs are effective, predictable, stable, and safe. This additive technique may also offer reversibility.

背景:近视手术矫正的局限性包括不准确、不稳定、对中央视区的治疗以及缺乏可逆性。KeraVision Intacs提供了一种解决这些缺点的替代方案。方法:我们对美国食品和药物管理局III期临床试验的95名受试者进行了1年的随访。结果:1年后,99%的患者(89 / 90)未矫正视力为20/40或更好。92%的眼睛(83 / 90)在1.00 D的预期矫正范围内,76%的眼睛(68 / 90)在0.50 D的预期矫正范围内。3个月时达到稳定,96%的受试者(90名中的86名)与之前的检查相比变化小于1.00 D。在一项亚研究中,89%的眼睛(65只中的58只)在一天的时间内变化在+/- 0.50 D范围内。角膜曲率如预期的那样改变,在中央光学区形成一个长形的非球面。大多数并发症或不良事件通过额外的药物治疗或手术干预得到控制,结果对受试者有利。结论:角膜植入术是有效、可预测、稳定、安全的。这种加性技术也可能提供可逆性。
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引用次数: 0
Cat-scratch neuroretinitis. 猫抓视网膜炎。
J Lombardo

Background: Cat-scratch disease is a subacute regional lymphadenitis, usually preceded by a history of a cat scratch or exposure to kittens. The disease is caused by Bartonella henselae, and possibly Bartonella quintana, pleomorphic gram-negative rods formerly known as Rochalimaea henselae and Rochalimaea quintana. Ocular involvement is rare and typically manifests as either Parinaud's oculoglandular syndrome or neuroretinitis. Patients with neuroretinitis resulting from cat-scratch disease may be asymptomatic or experience mild-to-severe vision loss. The clinical features, angiographic appearance, differential diagnosis, and management of cat-scratch neuroretinitis are discussed.

Case report: A 30-year-old white woman reported to the eye clinic with painless, decreased vision in the right eye. A diagnosis of cat scratch neuroretinitis was made on the basis of the history of cat scratch, clinical appearance, and angiographic findings. Treatment with oral ciprofloxacin restored vision to normal in 4 weeks.

Conclusion: Painless vision loss associated with optic nerve swelling and macular star exudate should alert suspicion of systemic disease. Additional findings--including positive history of a cat scratch, lymphadenopathy, and flu-like symptoms--may indicate Bartonella henselae or Bartonella quintana infection. While treatment remains controversial, appropriate serology testing may aid in the diagnosis and management of the underlying infection.

背景:猫抓病是一种亚急性区域性淋巴结炎,通常有猫抓史或与小猫接触史。这种疾病是由母鸡巴尔通体引起的,也可能是由金黄色巴尔通体引起的,这是一种多形性革兰氏阴性杆状体,以前称为母鸡罗氏菌和金黄色罗氏菌。眼部受累是罕见的,典型表现为Parinaud眼腺综合征或神经性视网膜炎。由猫抓病引起的神经视网膜炎患者可能无症状或经历轻度至重度视力丧失。本文讨论猫抓性神经视网膜炎的临床特征、血管造影表现、鉴别诊断和治疗。病例报告:一名30岁白人妇女因右眼无痛性视力下降而到眼科诊所就诊。根据猫抓史、临床表现和血管造影结果,诊断为猫抓神经视网膜炎。口服环丙沙星治疗4周后视力恢复正常。结论:无痛性视力丧失伴视神经肿胀和黄斑星状渗出,应警惕全身性疾病。其他发现——包括阳性猫抓史、淋巴结病和流感样症状——可能提示母鸡巴尔通体或金塔纳巴尔通体感染。虽然治疗仍有争议,但适当的血清学检测可能有助于诊断和管理潜在感染。
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引用次数: 0
Be aware of what we have. 要意识到我们所拥有的。
P B Freeman
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引用次数: 0
期刊
Journal of the American Optometric Association
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