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Treatment of Ingrown Toenail with a Minimally Invasive Nail Fixator: Comparative Study with Winograd Technique. 使用微创甲固定器治疗嵌甲:与 Winograd 技术的比较研究。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/22-024
Tuğrul Ergün, Mehmet Korkmaz, Dilan Ergün, Kaya Turan, Osman Görkem Muratoğlu, Haluk Cabuk

Background: Many surgical techniques have been reported for treatment of ingrown toenails. Occurrence of infection after matricectomy procedures could cause clinicians to prefer using external braces in the treatment of ingrown toenails. This study compares patients with ingrown toenails who underwent the nail fixation technique and the Winograd technique.

Methods: Patients who underwent ingrown toenail surgery were reviewed retrospectively. The patients' demographic characteristics (ie, age, gender, body mass index morphology according to Heifetz classification, surgical technique, visual analogue scale values, time to return to daily activities [days], complications, and satisfaction levels) were all recorded.

Results: Seventy patients were included in the study. Of the patients, 33 underwent nail fixation and 37 underwent the Winograd technique. No significant statistical differences were found in terms of patients' age, gender, body mass index, preoperative clinical features, long-term satisfaction, and ingrown toenail recurrence rates between the two groups, but time to return to daily activities and visual analogue scale values were statistically significantly lower in patients treated using nail fixation compared with the Winograd technique.

Conclusions: Nail fixation can be an effective surgical treatment option for ingrown toenail.

背景:治疗嵌甲的手术方法有很多。甲床切除术后感染的发生可能导致临床医生更倾向于使用外支架治疗嵌甲。本研究比较了接受甲固定技术和 Winograd 技术治疗的内生趾甲患者:对接受内生趾甲手术的患者进行回顾性研究。方法:对接受内生趾甲手术的患者进行回顾性研究,记录患者的人口统计学特征(年龄、性别、根据 Heifetz 分类的体重指数[BMI]形态、手术技术、视觉模拟量表(VAS)值、恢复日常活动的时间(天数)、并发症和满意度):研究共纳入了 70 名患者。其中,33 名患者接受了钢钉固定术,37 名患者接受了 Winograd 技术。两组患者在年龄、性别、体重指数、术前临床特征、长期满意度和内生趾甲复发率等方面均无明显统计学差异,但与 Winograd 技术相比,采用钉子固定术治疗的患者恢复日常活动的时间和 VAS 值明显较低:结论:钉子固定是治疗嵌甲的一种有效手术方法。
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引用次数: 0
The Impact of Forward Head Posture on Neck and Ankle Joint Position Sense: A Cross-Sectional Study. 头部前倾对颈部和踝关节位置感的影响:横断面研究
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/22-129
Amr A Abdel-Aziem, Dalia Mosaad, Elsadat S Soliman, Nouran A Ibrahim

Background: Forward head posture (FHP) decreases the neck position sense and creates tension in the neck muscles, which inversely affects the mechanics of the distal joints through body myofascia. Thus, this study investigated the effects of FHP on neck and ankle joint position sense, and conducted a comparison between the joint position sense of the right and left ankle.

Methods: Fifty-seven subjects were assigned according to the craniovertebral angle (CVA) into the FHP group (CVA <49°; n = 27) or the control group (CVA >49°; n = 30). Head and ankle joint repositioning accuracy was measured by using a cervical range-of-motion device and an isokinetic dynamometer, respectively.

Results: There was a significant increase in the joint position error (JPE) of the cervical flexion, extension, and right and left side bending motions of the FHP group compared to the control group (P < .05). There were significant increases in the JPE of the right and left ankle dorsiflexion and plantarflexion of the FHP group compared to the healthy group (P < .05). Moreover, the JPE of the right ankle dorsiflexion and plantarflexion of the FHP group were significantly higher than the left ankle (P < .05).

Conclusions: The FHP decreases the position sense of cervical flexion, extension, and right and left side bending motions, and the plantarflexion and dorsiflexion of both ankle joints, especially the right ankle joint.

背景:头部前倾姿势(FHP)会降低颈部位置感,并造成颈部肌肉紧张,从而通过身体肌筋膜对远端关节的力学产生反向影响。因此,本研究调查了 FHP 对颈部和踝关节位置感的影响,并对左右踝关节位置感进行了比较:方法:根据颅椎体角度(CVA)将 57 名受试者分配到 FHP 组(CVA 49°;n = 30)。分别使用颈椎活动范围装置和等速测力计测量头部和踝关节的复位准确性:结果:与对照组相比,FHP 组颈椎屈曲、伸展和左右侧屈运动的关节位置误差(JPE)明显增加(P < .05)。与健康组相比,FHP 组左右踝关节背屈和跖屈的关节位置误差(JPE)明显增加(P < .05)。此外,FHP 组的右踝关节背屈和跖屈的 JPE 明显高于左踝关节(P < .05):结论:FHP 会降低颈椎屈、伸、左右侧屈运动的位置感,以及双踝关节的跖屈和背伸,尤其是右踝关节。
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引用次数: 0
Association of Demographic Characteristics and Laboratory Values in Diabetic Foot Infections Leading to Lower-Extremity Amputation. 导致下肢截肢的糖尿病足感染中人口统计学特征与实验室值的关联。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/21-187
Allen J Kempf, Ellianne M Nasser, Idorenyin F Udoeyo, Isana Fils-Aime

Background: Lower-extremity amputations are a common complication of poorly controlled diabetes and contribute to significant morbidity and mortality in diabetic patients. We sought to determine whether objective data points obtained on presentation or hospital admission, including white blood cell (WBC) count, hemoglobin A1c (HbA1c), C-reactive protein (CRP), and descriptive patient demographics allow for the ability to predict optimal amputation levels and outcomes of lower-extremity amputation in the diabetic population.

Methods: A retrospective analysis of 162 patients was performed evaluating laboratory and descriptive values on hospital presentation for lower-extremity infection during a 16-year period. Occurrence of multiple amputations and level of amputation were assessed against laboratory values to determine whether these objective values would provide clinicians with a better understanding of amputations in the diabetic patient.

Results: The mean patient age was 60.6 years. A significantly higher percentage of patients who underwent amputations through the tibia and fibula or of the foot midtarsal were male compared with patients who underwent amputations of the thigh through femur. Patients who had amputations through the tibia and fibula had a significantly higher WBC count compared with patients who had a transmetatarsal amputation (P = .03). There was no significant difference in type or quantity of amputations when analyzing HbA1c and CRP levels.

Conclusions: An admission WBC count may be used as a predictor of lower-extremity amputation level and outcomes in diabetic infections. Although a statistically significant difference was not found for CRP or HbA1c levels between amputation procedures and number of procedures performed, these values remain useful in managing lower-extremity infections in diabetic patients.

背景:下肢截肢是糖尿病控制不佳的常见并发症,也是糖尿病患者发病率和死亡率的重要原因。我们试图确定在就诊或入院时获得的客观数据点(包括白细胞(WBC)计数、血红蛋白 A1c(HbA1c)、C 反应蛋白(CRP)和描述性患者人口统计学特征)是否能够预测糖尿病患者的最佳截肢水平和下肢截肢的结果:对 162 名患者进行了回顾性分析,评估了 16 年间因下肢感染入院的实验室和描述性数值。根据实验室数值评估了多处截肢的发生率和截肢程度,以确定这些客观数值是否能让临床医生更好地了解糖尿病患者的截肢情况:患者平均年龄为 60.6 岁。通过胫骨和腓骨或足跗骨中段截肢的患者中,男性比例明显高于通过股骨截肢的患者。与经跖骨截肢的患者相比,经胫骨和腓骨截肢的患者白细胞计数明显更高(P = 0.03)。在分析 HbA1c 和 CRP 水平时,截肢的类型和数量没有明显差异:结论:入院白细胞计数可作为糖尿病感染患者下肢截肢程度和预后的预测指标。虽然在截肢手术和手术次数之间未发现 CRP 或 HbA1c 水平有明显的统计学差异,但这些数值仍有助于管理糖尿病患者的下肢感染。
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引用次数: 0
Primary Arthrodesis versus Open Reduction and Internal Fixation for Lisfranc Joint Fracture-Dislocations in Adults: A Systematic Review. 成人 Lisfranc 关节断裂-脱位的初次关节固定术与开放复位和内固定术:系统性综述。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/21-232
Bryanna D Vesely, Lauren Michels, Matthew A King, Paula Gangopadhyay, Aaron T Scott

Background: The Lisfranc joint is an intricate podiatric medical structure that when injured can prove difficult to treat. No consensus has been established on optimal surgical management for this injury. It is widely debated whether open reduction and internal fixation or primary arthrodesis provides better outcomes for patients. Although literature has been published on this subject, no generalized guidelines have been created. The goal of this study was to analyze high-level meta-analyses to draw conclusions about surgical interventions for Lisfranc joint injuries.

Methods: A literature review was conducted to analyze outcomes of meta-analyses from January 1, 2016, to August 31, 2021. Only high-level evidence that reported at least one of the following outcomes was included: American Orthopaedic Foot and Ankle Society scale score, visual analog scale score, total complication rate, hardware removal rate, revision surgery rate, and secondary procedure rate.

Results: Six articles met the inclusion and exclusion criteria and were then analyzed. For all of the outcome measures, primary arthrodesis was equal or superior to open reduction and internal fixation.

Conclusions: We recommend primary arthrodesis over open reduction and internal fixation for adult Lisfranc injuries.

背景:Lisfranc 关节是一种复杂的足科医疗结构,一旦受伤就很难治疗。关于这种损伤的最佳手术治疗方法,目前尚未达成共识。究竟是切开复位内固定术还是初次关节置换术能为患者带来更好的治疗效果,目前还存在广泛争议。虽然已有相关文献发表,但尚未制定出通用指南。本研究的目的是通过分析高水平的荟萃分析,得出有关 Lisfranc 关节损伤手术干预的结论:对2016年1月1日至2021年8月31日期间的荟萃分析结果进行了文献综述分析。仅纳入了至少报告了以下一种结果的高级别证据:美国骨科足踝协会量表评分、视觉模拟量表评分、总并发症发生率、硬件移除率、翻修手术率和二次手术率:结果:有六篇文章符合纳入和排除标准,并进行了分析。就所有结果而言,初次关节置换术与切开复位内固定术效果相当或更优:结论:对于成人Lisfranc损伤,我们推荐初次关节固定术,而不是切开复位和内固定术。
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引用次数: 0
Winograd Wedge Resection Matrixectomy versus Partial Nail Avulsion with Chemical Cautery: A Tertiary Institution's Clinical Outcomes and Proposed Triaging Protocol. Winograd楔形切除基质切除术与化学烧灼法部分指甲剥离术:一家三级医疗机构的临床结果和建议的分流方案。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/22-108
Seng Juong Wong, Marabelle Li-Wen Heng, Siew-Keong Kwok, Kevin O T Koo, Nicholas E M Yeo

Background: Onychocryptosis, or ingrown toenail, is a common condition affecting patients of varying age groups, although usually, younger patients are affected.

Methods: We compared two techniques used in our institution: Winograd wedge resection with matrixectomy (WG-M) versus partial nail avulsion with phenolization of the nail matrix (PNA-P).

Results: Primary outcomes of interest were presence of nail regrowth and patient satisfaction postoperatively. Secondary outcomes were postoperative pain (within the first 2 weeks and after 2 weeks), postoperative inflammation, and healing time. A total of 65 patients were included in this study: 44 patients (19 female and 25 male patients), with a mean age of 45.7 years (range, 16-83 years) underwent WG-M in the orthopedic surgery department, whereas a total of 21 patients (10 female and 11 male patients), with a mean age of 44.5 years (range, 13 to 75 years) underwent PNA-P in the podiatry department. In patients who underwent WG-M, there was one case of regrowth (2.3%) compared with no regrowth cases (0%) in the PNA-P group. There was no significant difference in regrowth rate between the two procedures (P = .494). The satisfaction rate was high for both procedures: 100% patients in the WG-M group rated themselves better than before surgery, compared with 95.7% in the PNA-P group.

Conclusions: From our study, we conclude that both techniques (WG-M and PNA-P) are able to achieve similar clinical outcomes, with the PNA-P procedure being less invasive and less resource intensive, and also achieving a shorter healing time.

背景:趾甲内生或嵌甲是一种常见病,影响不同年龄段的患者,但通常是年轻患者:方法:我们比较了本院使用的两种技术:方法:我们比较了本院采用的两种技术:Winograd楔形切除加基质切除术(WG-M)与部分甲剥离加甲基质苯酚化术(PNA-P):主要结果是指甲是否再生以及患者术后的满意度。次要结果是术后疼痛(头两周内和两周后)、术后炎症和愈合时间。共有 65 名患者参与了这项研究:44名患者(19名女性和25名男性)在骨外科接受了WG-M手术,平均年龄为45.7岁(16-83岁);21名患者(10名女性和11名男性)在足科接受了PNA-P手术,平均年龄为44.5岁(13-75岁)。在接受 WG-M 治疗的患者中,有一例再生病例(2.3%),而在接受 PNA-P 治疗的患者中,没有再生病例(0%)。两种手术的再生率没有明显差异(P = .494)。两种手术的满意度都很高:WG-M组患者的满意度为100%,而PNA-P组患者的满意度为95.7%:通过研究,我们得出结论:两种技术(WG-M 和 PNA-P)都能达到相似的临床效果,其中 PNA-P 手术创伤更小、资源消耗更少,而且愈合时间更短。
{"title":"Winograd Wedge Resection Matrixectomy versus Partial Nail Avulsion with Chemical Cautery: A Tertiary Institution's Clinical Outcomes and Proposed Triaging Protocol.","authors":"Seng Juong Wong, Marabelle Li-Wen Heng, Siew-Keong Kwok, Kevin O T Koo, Nicholas E M Yeo","doi":"10.7547/22-108","DOIUrl":"10.7547/22-108","url":null,"abstract":"<p><strong>Background: </strong>Onychocryptosis, or ingrown toenail, is a common condition affecting patients of varying age groups, although usually, younger patients are affected.</p><p><strong>Methods: </strong>We compared two techniques used in our institution: Winograd wedge resection with matrixectomy (WG-M) versus partial nail avulsion with phenolization of the nail matrix (PNA-P).</p><p><strong>Results: </strong>Primary outcomes of interest were presence of nail regrowth and patient satisfaction postoperatively. Secondary outcomes were postoperative pain (within the first 2 weeks and after 2 weeks), postoperative inflammation, and healing time. A total of 65 patients were included in this study: 44 patients (19 female and 25 male patients), with a mean age of 45.7 years (range, 16-83 years) underwent WG-M in the orthopedic surgery department, whereas a total of 21 patients (10 female and 11 male patients), with a mean age of 44.5 years (range, 13 to 75 years) underwent PNA-P in the podiatry department. In patients who underwent WG-M, there was one case of regrowth (2.3%) compared with no regrowth cases (0%) in the PNA-P group. There was no significant difference in regrowth rate between the two procedures (P = .494). The satisfaction rate was high for both procedures: 100% patients in the WG-M group rated themselves better than before surgery, compared with 95.7% in the PNA-P group.</p><p><strong>Conclusions: </strong>From our study, we conclude that both techniques (WG-M and PNA-P) are able to achieve similar clinical outcomes, with the PNA-P procedure being less invasive and less resource intensive, and also achieving a shorter healing time.</p>","PeriodicalId":17241,"journal":{"name":"Journal of the American Podiatric Medical Association","volume":"114 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Achilles Tendon Stiffness in the Etiology of Sever Disease: A Shear Wave Elastography Study. 跟腱僵硬与 Sever 病的病因:剪切波弹性成像研究。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/22-167
Ersin Sensoz, Suna Sahın Edız, Omer Faruk Sevım, Selim Ergun, Engin Eceviz

Background: Sever disease is one of the most common causes of heel pain in growing children and adolescents. There is no consensus about etiology of Sever disease.

Methods: The study comprised 41 participants aged 8 to 13 years who visited the orthopedic outpatient clinic: 17 patients with Sever disease and 24 asymptomatic children. The middle third segment of the body of the Achilles tendon and the calcaneal insertion zone were separately assessed. Five measuring points for the quantitative value of each point were randomly selected. The color scale used in the Young's modulus shows the lowest values in blue and the highest values in red. The mean values were used for the statistical analysis.

Results: Less elasticity was detected at the insertional site for the control group (4.02 kPa versus 3.65 kPa), the situation was reversed in the body of the Achilles tendon and the elasticity of the study group was less than that of the control group (241.0 kPa versus 260.5 kPa). However, no statistically significant difference was found between the groups.

Conclusions: In conclusion, no difference was found in Achilles tendon elasticity between patients with Sever disease and healthy individuals in both the tendon body and the calcaneal insertionof the tendon. Achilles tendon elasticity has not been found to play a role in the etiology of Sever disease.

背景:赛弗病是导致成长中的儿童和青少年足跟痛的最常见原因之一。关于塞弗病的病因尚未达成共识:研究对象包括 41 名到骨科门诊就诊的 8 至 13 岁儿童:17名塞弗病患者和24名无症状儿童。分别评估了跟腱体中部第三段和小腿骨插入区。每个点的定量值随机选取五个测量点。杨氏模量使用的色标显示最低值为蓝色,最高值为红色。平均值用于统计分析:对照组插入部位的弹性较小(4.02 kPa 对 3.65 kPa),跟腱体部的情况正好相反,研究组的弹性小于对照组(241.0 kPa 对 260.5 kPa)。然而,研究组与对照组在统计学上没有明显差异:总之,在跟腱腱体和跟腱的小腿根部插入处,塞弗病患者和健康人的跟腱弹性没有差异。尚未发现跟腱弹性在塞弗病的病因中起作用。
{"title":"Achilles Tendon Stiffness in the Etiology of Sever Disease: A Shear Wave Elastography Study.","authors":"Ersin Sensoz, Suna Sahın Edız, Omer Faruk Sevım, Selim Ergun, Engin Eceviz","doi":"10.7547/22-167","DOIUrl":"10.7547/22-167","url":null,"abstract":"<p><strong>Background: </strong>Sever disease is one of the most common causes of heel pain in growing children and adolescents. There is no consensus about etiology of Sever disease.</p><p><strong>Methods: </strong>The study comprised 41 participants aged 8 to 13 years who visited the orthopedic outpatient clinic: 17 patients with Sever disease and 24 asymptomatic children. The middle third segment of the body of the Achilles tendon and the calcaneal insertion zone were separately assessed. Five measuring points for the quantitative value of each point were randomly selected. The color scale used in the Young's modulus shows the lowest values in blue and the highest values in red. The mean values were used for the statistical analysis.</p><p><strong>Results: </strong>Less elasticity was detected at the insertional site for the control group (4.02 kPa versus 3.65 kPa), the situation was reversed in the body of the Achilles tendon and the elasticity of the study group was less than that of the control group (241.0 kPa versus 260.5 kPa). However, no statistically significant difference was found between the groups.</p><p><strong>Conclusions: </strong>In conclusion, no difference was found in Achilles tendon elasticity between patients with Sever disease and healthy individuals in both the tendon body and the calcaneal insertionof the tendon. Achilles tendon elasticity has not been found to play a role in the etiology of Sever disease.</p>","PeriodicalId":17241,"journal":{"name":"Journal of the American Podiatric Medical Association","volume":"114 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Altmetrics and Traditional Bibliometrics in the Journal of the American Podiatric Medical Association and The Journal of Foot and Ankle Surgery. 美国足病医学协会杂志》和《足踝外科杂志》中 Altmetrics 与传统文献计量学之间的关联。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.7547/21-006
Dominick J Casciato, Jana Olivová, Bibi N Singh

Background: As the dissemination of scientific knowledge pervades social media, appraising impact with traditional bibliometrics led to the creation of alternative metrics, termed altmetrics. Lacking existent foot and ankle surgery literature altmetric analysis, we analyzed the 10 most-cited articles in the Journal of the American Podiatric Medical Association (JAPMA) and The Journal of Foot and Ankle Surgery (JFAS) in 2013 and 2017.

Methods: Citation count, Altmetric Attention Score (AAS), Mendeley Reads, and professional society-affiliated Twitter ages were collected and analyzed with descriptive statistics. Pearson correlation coefficient identified relationships between traditional and nontraditional metrics.

Results: The 40 articles showed a high median and large range in total citations for JAPMA (13.5 [range, 5-27]) and JFAS (28 [range, 5-69]). Media AAS Mendeley Reads also showed a high median with wide range for both JAPMA (32.5 [range, 0-135]) and JFAS (25 [range, 0-113)]. No significant correlation between total citations and AAS was seen in 2013 (r = -0.205; P = .388) or 2017 (r = -0.029; P = .903). The correlation between total citation count and Mendeley reads was significant in 2017 (r = 0.646; P = .002) but not in 2013 (r = -0.078; P = .744). Although cumulative AAS increased from 2013 to 2017 by 68.75%, with Twitter contributing most to both periods, there existed no significant correlation with Twitter age and the correlation coefficient between AAS and total citations (r = 0.655; P = .173).

Conclusions: The results of this investigation show the utility and predictivity of alternative metrics in complementing traditional bibliometrics and encourage the promotion of publications through journal-specific social media.

背景:随着科学知识在社交媒体上的传播,传统文献计量学对影响力的评估导致了替代指标的产生,这些指标被称为altmetrics。由于缺乏足踝外科文献的altmetric分析,我们分析了2013年和2017年《美国足病医学会杂志》(JAPMA)和《足踝外科杂志》(JFAS)上被引用最多的10篇文章:方法:收集引文数量、Altmetric关注度得分(AAS)、Mendeley阅读量和专业学会所属推特年龄,并进行描述性统计分析。皮尔逊相关系数确定了传统指标与非传统指标之间的关系:40篇文章中,JAPMA(13.5 [范围,5-27])和JFAS(28 [范围,5-69])的总引用次数中位数较高,范围较大。JAPMA 和 JFAS 的媒体 AAS Mendeley 阅读量中位数也较高(32.5 [范围,0-135]),范围较大(25 [范围,0-113])。2013年(r = -0.205;P = .388)和2017年(r = -0.029;P = .903)总被引频次与AAS之间没有明显的相关性。总引用次数与Mendeley阅读次数之间的相关性在2017年显著(r = 0.646; P = .002),但在2013年不显著(r = -0.078; P = .744)。虽然从2013年到2017年,累计AAS增加了68.75%,其中推特对这两个时期的贡献最大,但推特年龄与AAS和总被引次数之间的相关系数(r = 0.655; P = .173)不存在显著相关性:这项调查的结果表明,替代指标在补充传统文献计量学方面具有实用性和预测性,并鼓励通过特定期刊的社交媒体推广出版物。
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引用次数: 0
5-Aminolevulinic Acid-Mediated Photodynamic Therapy on Wound Healing: A Systemic Review of Human Evidences. 5-Aminolevulinic Acid-Mediated Photodynamic Therapy on Wound Healing:人类证据的系统回顾。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2023-12-21 DOI: 10.7547/23-015
Jianhua Huang, Hongwei Wang

Backgrounds: Skin wounds are a kind of refractory disease frequently encountered in clinic, which brings enormous burden to patients. Great efforts to address the dilemma of wound healing have yielded some encouraging results, but they are still unsatisfactory. 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) has been developed as a promising noninvasive treatment for skin wounds. A systematic review was performed to determine the existing evidence base for the clinical use of ALA-PDT on refractory wounds.

Methods: We conducted a PubMed search for English literature related to the clinical treatment of human skin ulcers by ALA-PDT published from 2012 to 2022, and performed a systematic review.

Results: 25 studies were ultimately selected in the present review and summarized, including six studies of skin cancer, five studies of chronic leg ulcers, three studies of erosive pustular skin diseases, and two studies of erosive oral lichen planus symptoms. A total of 335 patients had approximately 355 ulcers, of which 315 ulcers received photodynamic therapy and 276 improved with ALA-PDT. 20% ALA solution, wavelength between 600 nm and 670 nm, energy density of 120 J/cm2, frequency of once per week and 3 sessions were the most selected therapeutic parameters. Generally, ALA-PDT for wounds was effective with main adverse events of mild to moderate pain, and follow-up was generally conducted within 1 year.

Conclusions: This systematic review summarized the commonly used therapeutic parameters for ALA-PDT in the clinical treatment of skin wounds. After ALA-PDT alone or ALA-PDT combined with curettage, antibacterial and surgical treatment, all wounds healed well, and the adverse reactions were mainly mild to moderate pain, which could be relieved by cooling. ALA-PDT had proven to be a promising wound treatment modality through evidence of safety and efficacy.

背景:皮肤伤口是临床上经常遇到的一种难治性疾病,给患者带来了巨大的负担。为了解决伤口愈合的难题,人们付出了巨大的努力,取得了一些令人鼓舞的成果,但仍不尽如人意。5-氨基乙酰丙酸(ALA)介导的光动力疗法(PDT)已被开发为一种很有前景的非侵入性皮肤伤口治疗方法。为了确定将 ALA-PDT 用于难治性伤口临床治疗的现有证据基础,我们进行了一项系统性综述:我们在PubMed上检索了2012年至2022年发表的与ALA-PDT临床治疗人类皮肤溃疡相关的英文文献,并进行了系统性综述。结果:本综述最终筛选并总结了25项研究,其中包括6项皮肤癌研究、5项慢性腿部溃疡研究、3项糜烂性脓疱性皮肤病研究和2项糜烂性口腔扁平苔藓症状研究。共有 335 名患者患有约 355 个溃疡,其中 315 个溃疡接受了光动力疗法,276 个溃疡在 ALA-PDT 治疗后有所改善。20%的ALA溶液、600纳米至670纳米的波长、120焦耳/平方厘米的能量密度、每周一次的治疗频率和3次治疗是最常用的治疗参数。一般来说,ALA-PDT 治疗伤口效果显著,主要不良反应为轻度至中度疼痛,随访一般在 1 年内进行:本系统综述总结了ALA-PDT在皮肤伤口临床治疗中常用的治疗参数。经过ALA-PDT单独治疗或ALA-PDT联合刮宫、抗菌和手术治疗后,所有伤口均愈合良好,不良反应主要为轻中度疼痛,冷却后疼痛可缓解。ALA-PDT的安全性和有效性证明它是一种很有前途的伤口治疗方法。
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引用次数: 0
Cuboid Cobbles Hinder Elite Youth Football Player. 鹅卵石阻碍了青少年精英足球运动员的发展。
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2023-12-21 DOI: 10.7547/23-080
Jari Dahmen, Sjoerd A S Stufkens, Miki Dalmau-Pastor, Mario Maas, Gino M M J Kerkhoffs

We describe an elite youth football player who developed lateral foot pain of previously unknown origin. A thorough patient history and physical examination as well as an in-depth presentation of radiographic findings on Computed tomography (CT) and Magnetic Resonance Imaging (MRI) scan were described. Through this combination, the puzzle was resolved and a rare peroneus longus tendinopathy due to bony spurs in the cuboid groove was diagnosed. A peroneus longus exploration, release and reduction of the cuboidal bone spurs was performed and intensive rehabilitation phase followed. The patient successfully returned to performance and set a career in professional football.

我们描述了一名青少年精英足球运动员的足外侧疼痛症状,该疼痛之前原因不明。我们对患者的病史、体格检查以及计算机断层扫描(CT)和核磁共振成像(MRI)扫描的放射学结果进行了详细描述。通过这些综合检查,谜团被解开了,并确诊这是一种罕见的腓骨长肌肌腱病,是由于立方体沟内的骨刺引起的。医生对患者进行了腓骨长肌探查、松解和长方体骨刺切除术,随后进行了强化康复训练。患者成功恢复了运动能力,并开始了职业足球生涯。
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引用次数: 0
Is Subclassification by Number of Fracture Fragments Necessary for Sanders Type IV Calcaneal Fractures? 桑德斯 IV 型钙骨骨折是否有必要按骨折片数量进行子分类?
IF 0.7 4区 医学 Q4 ORTHOPEDICS Pub Date : 2023-11-01 DOI: 10.7547/21-135
Dong-Hee Kim, Jhee-Yun Kim, Kwang-Bok Lee

Background: The Sanders classification is a widely used method for classifying calcaneal fractures. Type IV fractures (>4 fragments) are known to vary in the number of fracture fragments. However, all relevant cases are classified as type IV irrespective of the number of fragments. We investigated the need for evaluation of postoperative prognoses based on radiologic factors and subtypes of Sanders classification type IV fractures.

Methods: Fifty-six Sanders type IV calcaneal fractures were enrolled between 2010 and 2018. Patients were divided into two groups according to the number of fragments: four fragments (group 1) and more than four fragments (group 2). Radiologic evaluation was performed using a postoperative recovery percentage calculated from postoperative reduction of the Böhler angle, Gissane angle, and vertical height. Radiologic evaluation was divided into two groups according to postoperative recovery: good and bad recovery groups. American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot score and visual analog scale (VAS) score were used for clinical outcome evaluation.

Results: There was no significant difference in AOFAS ankle-hindfoot score (P = .909) or VAS score (P = .963) between groups 1 and 2. However, there was a significant (P = .001) difference in AOFAS ankle-hindfoot score or VAS score between good and bad recovery groups.

Conclusions: Clinical results of Sanders type IV fractures were not related to the number of bone fragments but to the degree of injury to the Böhler angle, Gissane angle, and vertical height. Therefore, subtype classification of type IV calcaneal fractures is superfluous, and it is important to try to restore these parameters during surgery.

背景:桑德斯分类法是一种广泛使用的方骨骨折分类方法。众所周知,IV 型骨折(>4 个骨折片)的骨折片数量各不相同。然而,所有相关病例无论骨折片数量多少都被归类为 IV 型。我们研究了根据放射学因素和桑德斯分类 IV 型骨折亚型评估术后预后的必要性:2010 年至 2018 年间,我们共纳入了 56 例 Sanders IV 型小腿骨骨折患者。根据骨折片的数量将患者分为两组:4片(第1组)和4片以上(第2组)。根据术后波勒角、Gissane角和垂直高度的缩小情况计算术后恢复百分比,进行放射学评估。根据术后恢复情况将放射学评估分为两组:恢复良好组和恢复不良组。临床结果评估采用美国骨科足踝协会(AOFAS)踝关节-后足评分和视觉模拟量表(VAS)评分:第一组和第二组的 AOFAS 踝关节-后足评分(P = .909)或 VAS 评分(P = .963)无明显差异。然而,恢复良好组和恢复不良组的 AOFAS 踝关节-后足评分或 VAS 评分有明显差异(P = .001):结论:Sanders IV型骨折的临床结果与骨碎片的数量无关,而是与Böhler角、Gissane角和垂直高度的损伤程度有关。因此,IV型小腿骨骨折的亚型分类是多余的,重要的是在手术中尽量恢复这些参数。
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Journal of the American Podiatric Medical Association
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