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The Sovietisation of British medicine. 英国医学的苏联化
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-25 DOI: 10.1177/01410768241289064
Richard Spicer
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引用次数: 0
Bridging accelerated medical programmes and workforce demands: a critical evaluation of the four-year direct entry medical degree. 衔接速成医学课程和劳动力需求:对四年直接入学医学学位的批判性评估。
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-25 DOI: 10.1177/01410768241289812
Jun Jie Lim, Chris Roberts, Rajvir Singh, Jack Wellington
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引用次数: 0
Why a medical student's learning environment matters: the enabling effect of supportive social climates. 医学生的学习环境为何重要:支持性社会氛围的有利影响。
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-25 DOI: 10.1177/01410768241274048
Ajandek Eory, Tim Dornan
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引用次数: 0
COVID-19-related morbidity and mortality in people with multiple long-term conditions: a systematic review and meta-analysis of over 4 million people. 多种长期疾病患者中与 COVID-19 相关的发病率和死亡率:对 400 多万人进行的系统回顾和荟萃分析。
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-16 DOI: 10.1177/01410768241261507
Shukrat O Salisu-Olatunji, Yogini V Chudasama, Navjot Kaur, Zara Kayani, Babatunde A Odugbemi, Olasope Esther Bolodeoku, Shirley Akua Konnor, Elpida Vounzoulaki, Atanu Bhattacharjee, Radia Fahami, Jonathan Valabhji, Amitava Banerjee, Francesco Zaccardi, Clare L Gillies, Kamlesh Khunti

Objectives: To describe the direct impact of coronavirus disease 2019 (COVID-19) infection on morbidity and mortality in people with multiple long-term conditions (MLTCs).

Design: A systematic review and meta-analysis including observational studies.

Setting: Studies conducted between 1 January 2020 and 4 May 2023 across 51 countries were identified from five databases.

Participants: A total of 4,084,469 patients with confirmed COVID-19 infection.

Main outcome measures: Pooled risk ratios (RRs) for mortality, hospitalisation, severe disease, intensive care unit (ICU) admission and mechanical ventilation were estimated with random effect meta-analysis models.

Results: A total of 38,356 studies were identified and 111 included. In most (74%) of the studies, MLTCs referred to having two or more long-term conditions. Others described MLTCs by high weighted indices: the Charlson Comorbidity Index in 11% and the Clinical Frailty Score in 7%. Using the National Institutes of Health quality assessment tool for observational studies, the risk of bias was judged as low and moderate in 86 and 25 studies, respectively. Having MLTCs was associated with increased mortality (RR: 2.61 [95% CI: 2.27 to 3.0]); hospitalisation (2.4 [1.92 to 2.99]); severe disease (2.61 [1.92 to 3.54]); ICU admission (1.22 [1.07 to 1.39]) and mechanical ventilation (1.83 [1.18 to 2.84]) compared with those with no MLTCs. Pooled RRs for adverse outcomes were higher in children and young people compared with all age groups. In meta-regression analyses, men were more likely to need ICU admission (p = 0.013) and mechanical ventilation (p = 0.002).

Conclusions: Public health policies, clinical and preventative interventions should prioritise people with MLTCs to minimise direct adverse outcomes from COVID-19 disease.

目的描述冠状病毒病2019(COVID-19)感染对患有多种长期疾病(MLTC)的患者发病率和死亡率的直接影响:设计:系统回顾和荟萃分析,包括观察性研究:从 5 个数据库中筛选出 2020 年 1 月 1 日至 2023 年 5 月 4 日期间在 51 个国家开展的研究:主要结果测量:采用随机效应荟萃分析模型估算了死亡率、住院率、重症率、入住重症监护室(ICU)率和机械通气率的汇总风险比(RRs):共确定了 38 356 项研究,其中 111 项被纳入。在大多数研究中(74%),MLTC 指的是患有两种或两种以上的长期疾病。其他研究则通过高加权指数来描述多病种长期治疗中心:11%的研究采用夏尔森合并症指数,7%的研究采用临床虚弱评分。使用美国国立卫生研究院的观察性研究质量评估工具,分别有 86 项和 25 项研究的偏倚风险被判定为低度和中度。与没有使用多器官功能障碍的患者相比,使用多器官功能障碍会增加死亡率(RR:2.61 [95% CI:2.27 至 3.0])、住院率(2.4 [1.92 至 2.99])、重症率(2.61 [1.92 至 3.54])、入住重症监护室率(1.22 [1.07 至 1.39])和机械通气率(1.83 [1.18 至 2.84])。与所有年龄组相比,儿童和青少年不良结局的汇总RR值更高。在元回归分析中,男性更有可能需要入住重症监护室(p = 0.013)和机械通气(p = 0.002):结论:公共卫生政策、临床和预防干预措施应优先考虑多发性硬化症患者,以尽量减少 COVID-19 疾病的直接不良后果。
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引用次数: 0
English parallels to socialism: 1984-2024. 英国与社会主义的相似之处:1984-2024 年。
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-26 DOI: 10.1177/01410768241279619
Vasiliy Vlassov
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引用次数: 0
John Keats: the mystery years. 约翰-济慈:神秘岁月
IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-20 DOI: 10.1177/01410768241279029
Nick Black
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引用次数: 0
Helping our aspiring medics make an informed decision 帮助我们有抱负的医护人员做出明智的决定
IF 17.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-14 DOI: 10.1177/01410768241261209
Isaac KS Ng, Wilson GW Goh
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引用次数: 0
What do you need to be a scholar? And why? 成为学者需要什么?为什么?
IF 17.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-12 DOI: 10.1177/01410768241274569
Dinesh Bhugra
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引用次数: 0
How to advocate for vulnerable groups? 如何为弱势群体代言?
IF 17.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-12 DOI: 10.1177/01410768241274640
Dinesh Bhugra
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引用次数: 0
Advocate or not to advocate: what is the point? 提倡还是不提倡:意义何在?
IF 17.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-12 DOI: 10.1177/01410768241274638
Dinesh Bhugra
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引用次数: 0
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