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Thrombo-Embolism Risk and Prophylaxis amongst Hospitalized Patients in Two Hospitals in Cameroon: A Cross-sectional Study in Sub-Saharan Africa 喀麦隆两家医院住院患者的血栓栓塞风险和预防:撒哈拉以南非洲地区的横断面研究
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000367
B. Hamadou, F. Kamdem, H. Bessong, S. Ndongo-Amougou, L. KuateMfeukeu, C. Nganou, J. Boombhi, A. Ménanga, S. Kingue
Background: Venous thrombo-embolism (VTE) is frequent worldwide. It has not been sufficiency studied in sub-Saharan Africa, with few data on the prevalence and treatment from urban settings. Objectives: We sought to study the thromboembolic risk and rate of thrombo-prophylaxis for VTE in hospitalized patients. Methods: Between November 2016 and April 2017, we carried out a cross-sectional descriptive study in two hospitals in the Far North region- Cameroon. Participants were consenting adult patients hospitalized in the medical and surgical wards. We excluded those with diagnosed VTE. We evaluated the risk for VTE with Caprini Risk Assessment model and we assessed prophylaxis measures used. Results: A total of 520 patients were included - 282 (54.2%) from the surgical units and 238 (45.8%) from the medical units. The mean age was 49 ± 17 years, and 296 (57%) were males. The mean duration of hospitalization was 10 ± 9 days. Risk for VTE was seen in 284 (54.6%) patients -182 (64.5%) in the surgical units, and 102 (42.8%) in the medical units (p<0.001). Of those at risk, 165 (58.1%) were males. Adequate VTE thrombo-prophylaxis was carried out in 120 (42.3%) patients - 86 (47.3%) in the surgical units, and 33 (32.4%) in the medical units. Conclusion: The risk for VTE was seen in more than half of hospitalized patients in these semi-urban and rural hospitals. Less than half of those at risk received adequate thrombo-prophylaxis. The surgical units had significantly higher VTE risk and adequate prophylaxis rate than the medical units.
背景:静脉血栓栓塞(VTE)在世界范围内很常见。在撒哈拉以南非洲没有进行充分的研究,关于城市环境的流行和治疗的数据很少。目的:我们试图研究静脉血栓栓塞住院患者的血栓栓塞风险和血栓预防率。方法:2016年11月至2017年4月,我们在喀麦隆远北地区的两家医院进行了横断面描述性研究。参与者是在内科和外科病房住院的成年患者。我们排除了诊断为静脉血栓栓塞的患者。我们用卡普里尼风险评估模型评估静脉血栓栓塞的风险,并评估使用的预防措施。结果:共纳入患者520例,其中外科282例(54.2%),内科238例(45.8%)。平均年龄49±17岁,男性296例(57%)。平均住院时间为10±9天。有静脉血栓栓塞风险的患者有284例(54.6%),外科182例(64.5%),内科102例(42.8%)(p<0.001)。在高危人群中,165人(58.1%)为男性。120例(42.3%)患者进行了充分的静脉血栓预防,其中86例(47.3%)在外科病房,33例(32.4%)在内科病房。结论:在这些半城市和农村医院,半数以上的住院患者存在静脉血栓栓塞的风险。不到一半的高危人群接受了充分的血栓预防。外科单位的静脉血栓栓塞风险和预防率明显高于内科单位。
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引用次数: 1
The Risk Factors of Myocardial Infraction after Aortic Valve Replacement: A Systematic Review and Meta-Analysis 主动脉瓣置换术后心肌梗死的危险因素:系统回顾和荟萃分析
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000372
W. Hsieh, Po-Lin Chen, L. Goláň, Br, on Michael Henry, C. Kan, M. Omara, J. Lindner
Background: Myocardial infarction (MI) is a frequent perioperative complication of transcatheter aortic valve replacement (TAVR) associated with significant morbidity and mortality in comparison to surgical aortic valve replacement (SAVR). Objectives: This meta-analysis aims to assess the periprocedural incidence of MI, along with its risk factors in adult patients undergoing TAVR and SAVR due to severe aortic stenosis. Methods: A systematic literature review of the major electronic databases was performed to identify relevant articles published from January 2007 to September 2017. A meta-analysis was performed to quantify the incidence and prognostic factors for periprocedural MI following TAVR via “Review Manager (REVMAN) 5.3 Copenhagen”. Results: A total of 32 studies with a combined cohort of 15961 patients undergoing TAVR were included in this meta-analysis. Using a fixed-effects model, it was found that the TAVR procedure may lead to significantly low risk of myocardial infarction as compared to the SAVR (0.5% vs. 1.1%; RR, 0.44; 95% CI, 0.25-0.75; P=0.003; I2 =0%) The incidence and extent of periprocedural MI further to TAVR have been found associated with both short- and long-term mortality (p=0.002 and p=0.003, respectively). Conclusions: Incidence of MI was associated with lower risk of TAVR compared to SAVR. However, further studies are warranted to assess the role of CK-MB and troponin, as a prognostic factor to predict the clinical outcome. This study provides an evidence-based analysis on risk factors that could help predict the incidence of perioperative myocardial infarction in patients with severe aortic stenosis undergoing TAVR in comparison with SAVR.
背景:心肌梗死(MI)是经导管主动脉瓣置换术(TAVR)的常见围手术期并发症,与外科主动脉瓣置换术(SAVR)相比,其发病率和死亡率显著增高。目的:本荟萃分析旨在评估因严重主动脉狭窄而行TAVR和SAVR的成年患者的围手术期心肌梗死发生率及其危险因素。方法:对2007年1月至2017年9月发表的相关文献进行系统检索。通过“Review Manager (REVMAN) 5.3 Copenhagen”进行荟萃分析,量化TAVR术后围手术期心肌梗死的发生率和预后因素。结果:本荟萃分析共纳入32项研究,15961例接受TAVR的患者。使用固定效应模型,发现与SAVR相比,TAVR手术可能导致心肌梗死的风险显著降低(0.5% vs. 1.1%;RR 0.44;95% ci, 0.25-0.75;P = 0.003;术中心肌梗死的发生率和程度与TAVR的短期和长期死亡率相关(p=0.002和p=0.003)。结论:与SAVR相比,心肌梗死的发生率与TAVR的低风险相关。然而,需要进一步的研究来评估CK-MB和肌钙蛋白作为预测临床结果的预后因素的作用。本研究对严重主动脉狭窄患者行TAVR与SAVR的危险因素进行循证分析,有助于预测围手术期心肌梗死的发生率。
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引用次数: 0
A Commentary on 'Diagnose Vessel Course Distal to Occluded Artery using Heavily T2-weighted MRI in Mechanical Thrombectomy 机械取栓术中使用重t2加权MRI诊断闭塞动脉远端血管路径的评述
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000374
H. Minami
In endovascular thrombectomy for acute ischemic stroke due to large-vessel occlusion, occluded vessels are invisible on MRA or DSA. Heavily T2-weighted MRI sequence, which offers good contrast between cerebrospinal fluid and other brain structures, may contribute to resolve this issue. In this study the efficacy of this sequence in estimating vessel courses including unexpected aneurysms of the portion more distal to the occlusion site in endovascular thrombectomy is evaluated from the point of reliability, feasibility, and contribution to safety and also the detectability of aneurysms [1-4]. The heavily T2-weighted MRI sequence can contribute to improving the safety of maneuvers by clarifying the course of occluded vessels in endovascular thrombectomy for large-vessel occlusion [5].
在大血管闭塞引起的急性缺血性脑卒中的血管内取栓术中,被闭塞的血管在MRA或DSA上是不可见的。重t2加权MRI序列可提供脑脊液和其他脑结构的良好对比,可能有助于解决这一问题。在本研究中,从可靠性、可行性、对安全性的贡献以及动脉瘤的可检测性的角度,评估了该序列在血管内血栓切除术中估计血管进程(包括离闭塞部位远的部分的意外动脉瘤)的有效性[1-4]。在大血管闭塞的血管内取栓术中,重t2加权的MRI序列可以通过明确闭塞血管的路径来提高操作的安全性[5]。
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引用次数: 0
Wirsungorrhage due to Splenic Artery Aneurysm: Not a Chance Finding 脾动脉瘤引起的wirsunge:不是偶然发现
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000358
Shreya Gattani, Sunil Kumar, S. Agrawal, N. Raisinghani, Amit Baheti
Wirsungorrhage is a rare cause of hematochezia caused by a bleeding source in the pancreas, pancreatic duct or structures adjacent to it, such as the splenic artery that bleed into the pancreatic duct and thence to duodenum. We report a case of 38 year old male presenting with hypovolemic shock and fresh bleeding per rectum (hematochezia) secondary to splenic artery aneurysm diagnosed on the basis of computed tomography (CT) Angiography. In this case report we have highlighted the importance of angiography, when cause of gastrointestinal bleeding is not detectable by endoscopy.
wirsunge是一种罕见的由胰腺、胰管或其邻近结构出血引起的便血,如脾动脉出血进入胰管并进而进入十二指肠。我们报告一位38岁男性病患,经电脑断层扫描(CT)血管造影诊断为脾动脉瘤后继发的低血容量性休克及直肠新鲜出血(出血)。在这个病例报告中,我们强调了血管造影的重要性,当胃肠出血的原因不能通过内窥镜检测到。
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引用次数: 0
The Effect of Extracellular Matrix Patch on Femoral Artery after Endarterectomy 细胞外基质贴片对股动脉内膜切除术后股动脉的影响
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000371
S. Penović, I. Stula, Teo Borić, Z. Pogorelić
Background: CorMatrix is a unique extracellular matrix (ECM) that is made from porcine small intestinal submucosa (SIS). It is processed to remove cells but leaving molecules such as collagen, growth factors, proteins, and cytokines. This biomaterial does not calcify when surgically implanted, without any or with minor inflammatory reaction, supports native tissue repair by providing a bioscaffold that gives a patient’s own cells to repopulate and repair damaged tissue. It has been used for pericardial reconstruction, cardiac tissue repair, vascular applications and wound treatment. Methods: We used CorMatrix porcine SIS-ECM on four patients after endarterectomy of femoral arteries as patch angioplasty. They had a control examination by color Doppler ultrasound one year after the operation. Results: One of the patients died two days after the operation due to cardiac arrest. Two patients had a normal patency through the common femoral artery with CorMatrix. Spectral analysis showed normal triphasic flow pattern with adequate velocity. The third patient, who had stenosis of the external iliac artery in distal part before the operation, now had restenosis. There was patency through the common femoral artery and CorMatrix with only marginal wall thickening. Conclusion: CorMatrix porcine SIS-ECM proved as a good and safety patch.
背景:CorMatrix是一种独特的细胞外基质(ECM),由猪小肠黏膜下层(SIS)制成。它经过处理,去除细胞,但留下胶原蛋白、生长因子、蛋白质和细胞因子等分子。这种生物材料在手术植入时不会钙化,没有任何或轻微的炎症反应,通过提供生物支架,使患者自己的细胞重新填充和修复受损组织,从而支持原生组织修复。它已被用于心包重建、心脏组织修复、血管应用和伤口治疗。方法:采用CorMatrix猪SIS-ECM对4例股动脉内膜切除术后补片血管成形术患者进行治疗。术后1年行彩色多普勒超声对照检查。结果:1例患者术后2天因心脏骤停死亡。2例患者经CorMatrix经股总动脉通畅。光谱分析显示正常的三相流型,流速适当。第三例患者术前髂外动脉远端狭窄,现发生再狭窄。股总动脉及CorMatrix通畅,仅边缘壁增厚。结论:CorMatrix猪SIS-ECM是一种良好、安全的贴剂。
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引用次数: 1
Prevalence of Hypertension and Associate Risk Factors among Workers at Hawassa University, Ethiopia: An Institution Based Cross Sectional Study 埃塞俄比亚阿瓦萨大学工人高血压患病率及相关危险因素:一项基于机构的横断面研究
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000354
A. Esaiyas, T. Teshome, Dejene Kassa
Background: Hypertension is a serious public health concern which alone is estimated to cause 7.5 million (12.8% of all causes of death) deaths per year and it doubles the risk of many cardiovascular diseases. Objectives: To assess the prevalence of hypertension, the associated risk factors and knowledge plus practice related to hypertension. Materials and methods: The study was conducted in January-March 2014. Using simple random sampling technique 620 participants were selected. Data were collected by structured questionnaire. Data were analyzed using SPSS version 16 computer software. Result: The response rate of the study was 99.6%. Majority, 61.7% (376), of the respondents were male and 47.8% (272) were aged 25-34 years. Among respondents 122 (19.7%) were found to be hypertensive either by systolic or diastolic blood pressure out of which 54 (44%) were found hypertensive by both. Out of 122 hypertensive persons, 45 (36.9%) did not know their hypertension status. Some 192 (31%) of the respondents had a BMI score of 25 and above out of which 41 (21.4%) were obese. Respondents whose BMI measures ranged from 25-29.99 and those who were 30 years old and above were at increased risk of hypertension AOR=3.8 (95%CI 1.22-12) and AOR=3.90 (95%CI 1.10-14.01), respectively. Conclusion: Prevalence of hypertension among the study subjects was significantly high and most of them didn’t know their hypertension status. The level of hypertension related knowledge and practice of protective healthy life style were very low calling for urgent intervention.
背景:高血压是一个严重的公共卫生问题,据估计,仅高血压每年就造成750万人(占所有死亡原因的12.8%)死亡,并使许多心血管疾病的风险增加一倍。目的:了解我国高血压患病率、相关危险因素及高血压相关知识与实践情况。材料与方法:研究时间为2014年1月- 3月。采用简单随机抽样方法,选取620名参与者。采用结构化问卷法收集数据。数据分析采用SPSS 16版计算机软件。结果:本研究有效率为99.6%。61.7%(376人)为男性,47.8%(272人)年龄在25-34岁之间。在调查对象中,122人(19.7%)在收缩压或舒张压检测中发现高血压,其中54人(44%)在两种血压检测中都发现高血压。122例高血压患者中,有45例(36.9%)不了解自己的高血压状况。BMI指数在25以上的192人(31%)中,肥胖41人(21.4%)。BMI值在25-29.99之间和30岁及以上的受访者患高血压的风险分别为AOR=3.8 (95%CI 1.22-12)和3.90 (95%CI 1.10-14.01)。结论:研究对象高血压患病率明显偏高,且多数不了解自己的高血压状况。高血压相关知识和保护性健康生活方式的实践水平非常低,需要紧急干预。
{"title":"Prevalence of Hypertension and Associate Risk Factors among Workers at Hawassa University, Ethiopia: An Institution Based Cross Sectional Study","authors":"A. Esaiyas, T. Teshome, Dejene Kassa","doi":"10.4172/2329-6925.1000354","DOIUrl":"https://doi.org/10.4172/2329-6925.1000354","url":null,"abstract":"Background: Hypertension is a serious public health concern which alone is estimated to cause 7.5 million (12.8% of all causes of death) deaths per year and it doubles the risk of many cardiovascular diseases. Objectives: To assess the prevalence of hypertension, the associated risk factors and knowledge plus practice related to hypertension. Materials and methods: The study was conducted in January-March 2014. Using simple random sampling technique 620 participants were selected. Data were collected by structured questionnaire. Data were analyzed using SPSS version 16 computer software. Result: The response rate of the study was 99.6%. Majority, 61.7% (376), of the respondents were male and 47.8% (272) were aged 25-34 years. Among respondents 122 (19.7%) were found to be hypertensive either by systolic or diastolic blood pressure out of which 54 (44%) were found hypertensive by both. Out of 122 hypertensive persons, 45 (36.9%) did not know their hypertension status. Some 192 (31%) of the respondents had a BMI score of 25 and above out of which 41 (21.4%) were obese. Respondents whose BMI measures ranged from 25-29.99 and those who were 30 years old and above were at increased risk of hypertension AOR=3.8 (95%CI 1.22-12) and AOR=3.90 (95%CI 1.10-14.01), respectively. Conclusion: Prevalence of hypertension among the study subjects was significantly high and most of them didn’t know their hypertension status. The level of hypertension related knowledge and practice of protective healthy life style were very low calling for urgent intervention.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"38 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78805441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Local Anaesthetic Technique in Endovascular Abdominal Aortic Aneurysm Repair: Is it Time to Change the Paradigm? 局部麻醉技术在腹主动脉瘤血管内修复中的应用:是时候改变模式了吗?
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000376
A. Harky, K. S. Fan, Hiu Tat Kwok, J. Chan
Endovascular repair of abdominal aortic aneurysm has been the main treatment approach for the last two decades. Its outcomes have been reported to be satisfactory over such period and provided a lower morbidity and mortality rates when compared to the conventional open repairs. With time, the initial use of general anaesthetics has been replaced with regional anaesthesia and lately, the utilization of local anaesthesia (LA) for stenting the abdominal aortic aneurysms have been practiced in several centres internationally with excellent outcomes in selected cohorts. The key success in using LA is the advancement in the access techniques and less requirement for conventional open method to advance and deploy the stents through the femoral artery. This literature review aims at examining the current evidences behind the success of LA and whether it is going to be the new wide spread and standard method for anaesthesia in elective or emergency cases of endovascular repair of abdominal aortic aneurysms.
近二十年来,血管内修复术一直是腹主动脉瘤的主要治疗方法。据报道,在这段时间内,其结果令人满意,与传统的开放式修复相比,发病率和死亡率较低。随着时间的推移,最初使用全身麻醉已经被区域麻醉所取代,最近,局部麻醉(LA)用于腹主动脉瘤支架置入已经在国际上的几个中心进行了实践,在选定的队列中取得了良好的效果。使用LA的关键成功在于通路技术的进步,以及对传统开放方法通过股动脉推进和部署支架的要求的降低。本文献综述旨在探讨LA成功背后的现有证据,以及它是否将成为腹主动脉瘤血管内修复择期或急诊病例中广泛应用的新的标准麻醉方法。
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引用次数: 1
Safety and Efficacy of Amniotic Membrane Implant in Venous Leg Ulcers 羊膜植入治疗下肢静脉性溃疡的安全性和有效性
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000373
J. Marinel-lo, M. Serra-Prat, C. Albuxeich, P. Carreño, J. Lopez-Palencia, E. Palomera, J. Alós
Objective: To assess the safety and efficacy of amniotic membrane (AM) application in venous leg ulcers (VLU). Methodology: Design: non-controlled pre-post clinical trial. A unique AM fragment was placed on the ulcer in strict sterility conditions. Main outcome measures: total healing rate, percentage of ulcer area reduction and diurnal and nocturnal pain assessment. Control visits: at baseline and 1, 2, 3, 4 and 8 weeks after treatment. Results: Ten patients were recruited (79.6 years). 3 weeks after AM implant, pain had completely disappeared and ulcer area had reduced to nearly halved and, 8 weeks after AM implant, ulcer area was reduced in more than 80% and in two thirds of patients the ulcer was completely healed. No relevant side effects were observed. Conclusions: The present study brings new evidence reinforcing the idea that AM dressing is a safety and effective alternative to heal VLU
目的:评价羊膜(AM)应用于下肢静脉性溃疡(VLU)的安全性和有效性。设计:非对照临床前后试验。在严格的无菌条件下,一个独特的AM片段被放置在溃疡上。主要观察指标:总治愈率、溃疡面积缩小百分比、昼夜疼痛评估。对照访问:在基线和治疗后1、2、3、4和8周。结果:纳入10例患者(79.6岁)。植入AM后3周,疼痛完全消失,溃疡面积缩小近一半,植入AM后8周,溃疡面积缩小80%以上,三分之二的患者溃疡完全愈合。未观察到相关副作用。结论:本研究提供了新的证据,加强了AM敷料是一种安全有效的治疗VLU的替代方法
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引用次数: 0
Study of Cognitive Impairment between Diabetic Foot Patients 糖尿病足患者认知功能障碍的研究
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000369
W. M. Gamal, M. A. Abbas, Amira Mohamed
Background: Diabetic foot (DF) is one of the most widespread type 2 diabetes mellitus “T2DM” complications, it originates from the conjunction of neuropathy and vascular disease. Some reports suggest that amputees might be prone to cognitive decline. Aim of the work: To investigate the cognitive function of DF patients and the relations between it and diabetes complications& comorbidities. Patients and methods: One hundred dementia-free subjects with DF aged >18 were enrolled in the study through the period from March to August 2018 from the Vascular outpatient clinic of Qena University Hospital and only patients whom gave consent have joined the study. The mean age of the study group was 61 years, with 70 males and 30 females, their demographic characters were recorded and medical cognitive tests were applied. Patients have been undergone clinical vascular examination, data on diabetic complications and comorbidities were gathered; (HbA1c) tests were carried out for all patients. Results: The mean Mini-Mental State Examination “MMSE” score of subjects was 24.6 and 40% had global cognitive dysfunction (MMSE ≤ 24). Between elderly subjects (aged ≥ 65), MMSE impairment was linked to amputation, episodic memory impairment was connected to foot amputation and complications. Elderly subjects with HbA1c >7% had elevated odds of psychomotor slowness and abstract reasoning impairment. However, such findings were not present in adult subjects <65 years. Conclusion: Diabetic foot is the severest form of T2DM that causes significant impairment in all cognitive domains. The severity of depression is significantly increased with the intensity of amputation.
背景:糖尿病足(DF)是2型糖尿病(T2DM)最常见的并发症之一,起源于神经病变和血管病变的结合。一些报告显示,截肢者可能容易出现认知能力下降。目的:探讨糖尿病患者的认知功能及其与糖尿病并发症及合并症的关系。患者和方法:于2018年3月至8月从Qena大学医院血管门诊招募100名年龄>18岁的无痴呆受试者,只有同意的患者才加入研究。研究组平均年龄61岁,男性70例,女性30例,记录其人口学特征并进行医学认知测试。对患者进行临床血管检查,收集糖尿病并发症及合并症的数据;对所有患者进行糖化血红蛋白(HbA1c)检测。结果:受试者MMSE平均评分为24.6分,整体认知功能障碍(MMSE≤24)占40%。在老年受试者(年龄≥65岁)中,MMSE障碍与截肢有关,情景记忆障碍与足部截肢和并发症有关。HbA1c >7%的老年受试者出现精神运动迟缓和抽象推理障碍的几率较高。然而,这一发现在65岁以下的成人受试者中并不存在。结论:糖尿病足是最严重的T2DM形式,可导致所有认知领域的显著损害。抑郁症的严重程度随截肢强度的增加而明显增加。
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引用次数: 1
Predictors and Outcomes of Gastrointestinal Bleeding in Patients with Acute Myocardial Infarction 急性心肌梗死患者消化道出血的预测因素和预后
Pub Date : 2018-01-01 DOI: 10.4172/2329-6925.1000368
T. Tran-Thi-Khanh, D. Phan-Thi-Thuy, S. Duong-Quy
Background and objectives: The risk of gastrointestinal bleeding in patients hospitalized with acute myocardial infarction is higher due to antiplatelet and anticoagulant agents along with revascularization. There are limited data about predictors and implications of gastrointestinal bleeding in acute myocardial infarction. Our research aims to investigate the incidence, predictors, clinical outcomes associated with gastrointestinal bleeding in patients with acute myocardial infarction. Patients and methods: Cross sectional study was conducted. All patients diagnosed with acute myocardial infarction at Tam Duc Heart hospital from January 2013 to March 2017 were enrolled. Results: A total of 643 patients with acute myocardial infarction were included (67.2 ± 13.8 years). Gastrointestinal bleeding occurred in 9.5%. Multiple logistic regression analysis demonstrated that female (OR 2.21; CI95%: 1.02- 4.74; p=0.044), pneumonia (OR 2.76; CI95%: 1.25-6.08; p=0.012), impared renal function (OR 4.65; CI95%: 2.08- 10.4; p<0.001) were independent predictors of gastrointestinal bleeding. Gastrointestinal bleeding was significantly associated with prolonged hospital stay (21.8 vs. 9.7 days; p<0.01), increased the need of transfusion (39.4% vs. 3.9%; p<0.001), higher in-hospital mortality (21.3% vs. 7.2%; p<0.01). Conclusion: The rate of gastrointestinal bleeding was 9.5%. Female, pneumonia, impared renal function were independent predictors in patients with acute myocardial infartion.
背景与目的:急性心肌梗死住院患者由于使用抗血小板和抗凝药物以及血运重建术而发生胃肠道出血的风险较高。关于急性心肌梗死中消化道出血的预测因素和影响的数据有限。我们的研究旨在探讨急性心肌梗死患者胃肠道出血的发生率、预测因素和临床结局。患者及方法:采用横断面研究。纳入2013年1月至2017年3月在谭德心脏医院诊断为急性心肌梗死的所有患者。结果:共纳入急性心肌梗死患者643例(67.2±13.8年)。9.5%发生胃肠出血。多元logistic回归分析显示,女性(OR 2.21;Ci95%: 1.02- 4.74;p=0.044),肺炎(OR 2.76;CI95%: 1.25 - -6.08;p=0.012),肾功能受损(OR 4.65;Ci95%: 2.08- 10.4;P <0.001)是胃肠道出血的独立预测因子。胃肠出血与住院时间延长显著相关(21.8天vs 9.7天;P <0.01),输血需求增加(39.4% vs. 3.9%;P <0.001),住院死亡率较高(21.3% vs. 7.2%;p < 0.01)。结论:消化道出血发生率为9.5%。女性、肺炎、肾功能损害是急性心肌梗死患者的独立预测因素。
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引用次数: 0
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Journal of Vascular Medicine & Surgery
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