Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000367
B. Hamadou, F. Kamdem, H. Bessong, S. Ndongo-Amougou, L. KuateMfeukeu, C. Nganou, J. Boombhi, A. Ménanga, S. Kingue
Background: Venous thrombo-embolism (VTE) is frequent worldwide. It has not been sufficiency studied in sub-Saharan Africa, with few data on the prevalence and treatment from urban settings. Objectives: We sought to study the thromboembolic risk and rate of thrombo-prophylaxis for VTE in hospitalized patients. Methods: Between November 2016 and April 2017, we carried out a cross-sectional descriptive study in two hospitals in the Far North region- Cameroon. Participants were consenting adult patients hospitalized in the medical and surgical wards. We excluded those with diagnosed VTE. We evaluated the risk for VTE with Caprini Risk Assessment model and we assessed prophylaxis measures used. Results: A total of 520 patients were included - 282 (54.2%) from the surgical units and 238 (45.8%) from the medical units. The mean age was 49 ± 17 years, and 296 (57%) were males. The mean duration of hospitalization was 10 ± 9 days. Risk for VTE was seen in 284 (54.6%) patients -182 (64.5%) in the surgical units, and 102 (42.8%) in the medical units (p<0.001). Of those at risk, 165 (58.1%) were males. Adequate VTE thrombo-prophylaxis was carried out in 120 (42.3%) patients - 86 (47.3%) in the surgical units, and 33 (32.4%) in the medical units. Conclusion: The risk for VTE was seen in more than half of hospitalized patients in these semi-urban and rural hospitals. Less than half of those at risk received adequate thrombo-prophylaxis. The surgical units had significantly higher VTE risk and adequate prophylaxis rate than the medical units.
{"title":"Thrombo-Embolism Risk and Prophylaxis amongst Hospitalized Patients in Two Hospitals in Cameroon: A Cross-sectional Study in Sub-Saharan Africa","authors":"B. Hamadou, F. Kamdem, H. Bessong, S. Ndongo-Amougou, L. KuateMfeukeu, C. Nganou, J. Boombhi, A. Ménanga, S. Kingue","doi":"10.4172/2329-6925.1000367","DOIUrl":"https://doi.org/10.4172/2329-6925.1000367","url":null,"abstract":"Background: Venous thrombo-embolism (VTE) is frequent worldwide. It has not been sufficiency studied in sub-Saharan Africa, with few data on the prevalence and treatment from urban settings. Objectives: We sought to study the thromboembolic risk and rate of thrombo-prophylaxis for VTE in hospitalized patients. Methods: Between November 2016 and April 2017, we carried out a cross-sectional descriptive study in two hospitals in the Far North region- Cameroon. Participants were consenting adult patients hospitalized in the medical and surgical wards. We excluded those with diagnosed VTE. We evaluated the risk for VTE with Caprini Risk Assessment model and we assessed prophylaxis measures used. Results: A total of 520 patients were included - 282 (54.2%) from the surgical units and 238 (45.8%) from the medical units. The mean age was 49 ± 17 years, and 296 (57%) were males. The mean duration of hospitalization was 10 ± 9 days. Risk for VTE was seen in 284 (54.6%) patients -182 (64.5%) in the surgical units, and 102 (42.8%) in the medical units (p<0.001). Of those at risk, 165 (58.1%) were males. Adequate VTE thrombo-prophylaxis was carried out in 120 (42.3%) patients - 86 (47.3%) in the surgical units, and 33 (32.4%) in the medical units. Conclusion: The risk for VTE was seen in more than half of hospitalized patients in these semi-urban and rural hospitals. Less than half of those at risk received adequate thrombo-prophylaxis. The surgical units had significantly higher VTE risk and adequate prophylaxis rate than the medical units.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"47 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75820210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000372
W. Hsieh, Po-Lin Chen, L. Goláň, Br, on Michael Henry, C. Kan, M. Omara, J. Lindner
Background: Myocardial infarction (MI) is a frequent perioperative complication of transcatheter aortic valve replacement (TAVR) associated with significant morbidity and mortality in comparison to surgical aortic valve replacement (SAVR). Objectives: This meta-analysis aims to assess the periprocedural incidence of MI, along with its risk factors in adult patients undergoing TAVR and SAVR due to severe aortic stenosis. Methods: A systematic literature review of the major electronic databases was performed to identify relevant articles published from January 2007 to September 2017. A meta-analysis was performed to quantify the incidence and prognostic factors for periprocedural MI following TAVR via “Review Manager (REVMAN) 5.3 Copenhagen”. Results: A total of 32 studies with a combined cohort of 15961 patients undergoing TAVR were included in this meta-analysis. Using a fixed-effects model, it was found that the TAVR procedure may lead to significantly low risk of myocardial infarction as compared to the SAVR (0.5% vs. 1.1%; RR, 0.44; 95% CI, 0.25-0.75; P=0.003; I2 =0%) The incidence and extent of periprocedural MI further to TAVR have been found associated with both short- and long-term mortality (p=0.002 and p=0.003, respectively). Conclusions: Incidence of MI was associated with lower risk of TAVR compared to SAVR. However, further studies are warranted to assess the role of CK-MB and troponin, as a prognostic factor to predict the clinical outcome. This study provides an evidence-based analysis on risk factors that could help predict the incidence of perioperative myocardial infarction in patients with severe aortic stenosis undergoing TAVR in comparison with SAVR.
{"title":"The Risk Factors of Myocardial Infraction after Aortic Valve Replacement: A Systematic Review and Meta-Analysis","authors":"W. Hsieh, Po-Lin Chen, L. Goláň, Br, on Michael Henry, C. Kan, M. Omara, J. Lindner","doi":"10.4172/2329-6925.1000372","DOIUrl":"https://doi.org/10.4172/2329-6925.1000372","url":null,"abstract":"Background: Myocardial infarction (MI) is a frequent perioperative complication of transcatheter aortic valve replacement (TAVR) associated with significant morbidity and mortality in comparison to surgical aortic valve replacement (SAVR). Objectives: This meta-analysis aims to assess the periprocedural incidence of MI, along with its risk factors in adult patients undergoing TAVR and SAVR due to severe aortic stenosis. Methods: A systematic literature review of the major electronic databases was performed to identify relevant articles published from January 2007 to September 2017. A meta-analysis was performed to quantify the incidence and prognostic factors for periprocedural MI following TAVR via “Review Manager (REVMAN) 5.3 Copenhagen”. Results: A total of 32 studies with a combined cohort of 15961 patients undergoing TAVR were included in this meta-analysis. Using a fixed-effects model, it was found that the TAVR procedure may lead to significantly low risk of myocardial infarction as compared to the SAVR (0.5% vs. 1.1%; RR, 0.44; 95% CI, 0.25-0.75; P=0.003; I2 =0%) The incidence and extent of periprocedural MI further to TAVR have been found associated with both short- and long-term mortality (p=0.002 and p=0.003, respectively). Conclusions: Incidence of MI was associated with lower risk of TAVR compared to SAVR. However, further studies are warranted to assess the role of CK-MB and troponin, as a prognostic factor to predict the clinical outcome. This study provides an evidence-based analysis on risk factors that could help predict the incidence of perioperative myocardial infarction in patients with severe aortic stenosis undergoing TAVR in comparison with SAVR.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"06 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80858916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000374
H. Minami
In endovascular thrombectomy for acute ischemic stroke due to large-vessel occlusion, occluded vessels are invisible on MRA or DSA. Heavily T2-weighted MRI sequence, which offers good contrast between cerebrospinal fluid and other brain structures, may contribute to resolve this issue. In this study the efficacy of this sequence in estimating vessel courses including unexpected aneurysms of the portion more distal to the occlusion site in endovascular thrombectomy is evaluated from the point of reliability, feasibility, and contribution to safety and also the detectability of aneurysms [1-4]. The heavily T2-weighted MRI sequence can contribute to improving the safety of maneuvers by clarifying the course of occluded vessels in endovascular thrombectomy for large-vessel occlusion [5].
{"title":"A Commentary on 'Diagnose Vessel Course Distal to Occluded Artery using Heavily T2-weighted MRI in Mechanical Thrombectomy","authors":"H. Minami","doi":"10.4172/2329-6925.1000374","DOIUrl":"https://doi.org/10.4172/2329-6925.1000374","url":null,"abstract":"In endovascular thrombectomy for acute ischemic stroke due to large-vessel occlusion, occluded vessels are invisible on MRA or DSA. Heavily T2-weighted MRI sequence, which offers good contrast between cerebrospinal fluid and other brain structures, may contribute to resolve this issue. In this study the efficacy of this sequence in estimating vessel courses including unexpected aneurysms of the portion more distal to the occlusion site in endovascular thrombectomy is evaluated from the point of reliability, feasibility, and contribution to safety and also the detectability of aneurysms [1-4]. The heavily T2-weighted MRI sequence can contribute to improving the safety of maneuvers by clarifying the course of occluded vessels in endovascular thrombectomy for large-vessel occlusion [5].","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"2007 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82499799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000358
Shreya Gattani, Sunil Kumar, S. Agrawal, N. Raisinghani, Amit Baheti
Wirsungorrhage is a rare cause of hematochezia caused by a bleeding source in the pancreas, pancreatic duct or structures adjacent to it, such as the splenic artery that bleed into the pancreatic duct and thence to duodenum. We report a case of 38 year old male presenting with hypovolemic shock and fresh bleeding per rectum (hematochezia) secondary to splenic artery aneurysm diagnosed on the basis of computed tomography (CT) Angiography. In this case report we have highlighted the importance of angiography, when cause of gastrointestinal bleeding is not detectable by endoscopy.
{"title":"Wirsungorrhage due to Splenic Artery Aneurysm: Not a Chance Finding","authors":"Shreya Gattani, Sunil Kumar, S. Agrawal, N. Raisinghani, Amit Baheti","doi":"10.4172/2329-6925.1000358","DOIUrl":"https://doi.org/10.4172/2329-6925.1000358","url":null,"abstract":"Wirsungorrhage is a rare cause of hematochezia caused by a bleeding source in the pancreas, pancreatic duct or structures adjacent to it, such as the splenic artery that bleed into the pancreatic duct and thence to duodenum. We report a case of 38 year old male presenting with hypovolemic shock and fresh bleeding per rectum (hematochezia) secondary to splenic artery aneurysm diagnosed on the basis of computed tomography (CT) Angiography. In this case report we have highlighted the importance of angiography, when cause of gastrointestinal bleeding is not detectable by endoscopy.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"37 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86644347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000371
S. Penović, I. Stula, Teo Borić, Z. Pogorelić
Background: CorMatrix is a unique extracellular matrix (ECM) that is made from porcine small intestinal submucosa (SIS). It is processed to remove cells but leaving molecules such as collagen, growth factors, proteins, and cytokines. This biomaterial does not calcify when surgically implanted, without any or with minor inflammatory reaction, supports native tissue repair by providing a bioscaffold that gives a patient’s own cells to repopulate and repair damaged tissue. It has been used for pericardial reconstruction, cardiac tissue repair, vascular applications and wound treatment. Methods: We used CorMatrix porcine SIS-ECM on four patients after endarterectomy of femoral arteries as patch angioplasty. They had a control examination by color Doppler ultrasound one year after the operation. Results: One of the patients died two days after the operation due to cardiac arrest. Two patients had a normal patency through the common femoral artery with CorMatrix. Spectral analysis showed normal triphasic flow pattern with adequate velocity. The third patient, who had stenosis of the external iliac artery in distal part before the operation, now had restenosis. There was patency through the common femoral artery and CorMatrix with only marginal wall thickening. Conclusion: CorMatrix porcine SIS-ECM proved as a good and safety patch.
{"title":"The Effect of Extracellular Matrix Patch on Femoral Artery after Endarterectomy","authors":"S. Penović, I. Stula, Teo Borić, Z. Pogorelić","doi":"10.4172/2329-6925.1000371","DOIUrl":"https://doi.org/10.4172/2329-6925.1000371","url":null,"abstract":"Background: CorMatrix is a unique extracellular matrix (ECM) that is made from porcine small intestinal submucosa (SIS). It is processed to remove cells but leaving molecules such as collagen, growth factors, proteins, and cytokines. This biomaterial does not calcify when surgically implanted, without any or with minor inflammatory reaction, supports native tissue repair by providing a bioscaffold that gives a patient’s own cells to repopulate and repair damaged tissue. It has been used for pericardial reconstruction, cardiac tissue repair, vascular applications and wound treatment. Methods: We used CorMatrix porcine SIS-ECM on four patients after endarterectomy of femoral arteries as patch angioplasty. They had a control examination by color Doppler ultrasound one year after the operation. Results: One of the patients died two days after the operation due to cardiac arrest. Two patients had a normal patency through the common femoral artery with CorMatrix. Spectral analysis showed normal triphasic flow pattern with adequate velocity. The third patient, who had stenosis of the external iliac artery in distal part before the operation, now had restenosis. There was patency through the common femoral artery and CorMatrix with only marginal wall thickening. Conclusion: CorMatrix porcine SIS-ECM proved as a good and safety patch.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"33 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80991271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000354
A. Esaiyas, T. Teshome, Dejene Kassa
Background: Hypertension is a serious public health concern which alone is estimated to cause 7.5 million (12.8% of all causes of death) deaths per year and it doubles the risk of many cardiovascular diseases. Objectives: To assess the prevalence of hypertension, the associated risk factors and knowledge plus practice related to hypertension. Materials and methods: The study was conducted in January-March 2014. Using simple random sampling technique 620 participants were selected. Data were collected by structured questionnaire. Data were analyzed using SPSS version 16 computer software. Result: The response rate of the study was 99.6%. Majority, 61.7% (376), of the respondents were male and 47.8% (272) were aged 25-34 years. Among respondents 122 (19.7%) were found to be hypertensive either by systolic or diastolic blood pressure out of which 54 (44%) were found hypertensive by both. Out of 122 hypertensive persons, 45 (36.9%) did not know their hypertension status. Some 192 (31%) of the respondents had a BMI score of 25 and above out of which 41 (21.4%) were obese. Respondents whose BMI measures ranged from 25-29.99 and those who were 30 years old and above were at increased risk of hypertension AOR=3.8 (95%CI 1.22-12) and AOR=3.90 (95%CI 1.10-14.01), respectively. Conclusion: Prevalence of hypertension among the study subjects was significantly high and most of them didn’t know their hypertension status. The level of hypertension related knowledge and practice of protective healthy life style were very low calling for urgent intervention.
{"title":"Prevalence of Hypertension and Associate Risk Factors among Workers at Hawassa University, Ethiopia: An Institution Based Cross Sectional Study","authors":"A. Esaiyas, T. Teshome, Dejene Kassa","doi":"10.4172/2329-6925.1000354","DOIUrl":"https://doi.org/10.4172/2329-6925.1000354","url":null,"abstract":"Background: Hypertension is a serious public health concern which alone is estimated to cause 7.5 million (12.8% of all causes of death) deaths per year and it doubles the risk of many cardiovascular diseases. Objectives: To assess the prevalence of hypertension, the associated risk factors and knowledge plus practice related to hypertension. Materials and methods: The study was conducted in January-March 2014. Using simple random sampling technique 620 participants were selected. Data were collected by structured questionnaire. Data were analyzed using SPSS version 16 computer software. Result: The response rate of the study was 99.6%. Majority, 61.7% (376), of the respondents were male and 47.8% (272) were aged 25-34 years. Among respondents 122 (19.7%) were found to be hypertensive either by systolic or diastolic blood pressure out of which 54 (44%) were found hypertensive by both. Out of 122 hypertensive persons, 45 (36.9%) did not know their hypertension status. Some 192 (31%) of the respondents had a BMI score of 25 and above out of which 41 (21.4%) were obese. Respondents whose BMI measures ranged from 25-29.99 and those who were 30 years old and above were at increased risk of hypertension AOR=3.8 (95%CI 1.22-12) and AOR=3.90 (95%CI 1.10-14.01), respectively. Conclusion: Prevalence of hypertension among the study subjects was significantly high and most of them didn’t know their hypertension status. The level of hypertension related knowledge and practice of protective healthy life style were very low calling for urgent intervention.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"38 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78805441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000376
A. Harky, K. S. Fan, Hiu Tat Kwok, J. Chan
Endovascular repair of abdominal aortic aneurysm has been the main treatment approach for the last two decades. Its outcomes have been reported to be satisfactory over such period and provided a lower morbidity and mortality rates when compared to the conventional open repairs. With time, the initial use of general anaesthetics has been replaced with regional anaesthesia and lately, the utilization of local anaesthesia (LA) for stenting the abdominal aortic aneurysms have been practiced in several centres internationally with excellent outcomes in selected cohorts. The key success in using LA is the advancement in the access techniques and less requirement for conventional open method to advance and deploy the stents through the femoral artery. This literature review aims at examining the current evidences behind the success of LA and whether it is going to be the new wide spread and standard method for anaesthesia in elective or emergency cases of endovascular repair of abdominal aortic aneurysms.
{"title":"Local Anaesthetic Technique in Endovascular Abdominal Aortic Aneurysm Repair: Is it Time to Change the Paradigm?","authors":"A. Harky, K. S. Fan, Hiu Tat Kwok, J. Chan","doi":"10.4172/2329-6925.1000376","DOIUrl":"https://doi.org/10.4172/2329-6925.1000376","url":null,"abstract":"Endovascular repair of abdominal aortic aneurysm has been the main treatment approach for the last two decades. Its outcomes have been reported to be satisfactory over such period and provided a lower morbidity and mortality rates when compared to the conventional open repairs. With time, the initial use of general anaesthetics has been replaced with regional anaesthesia and lately, the utilization of local anaesthesia (LA) for stenting the abdominal aortic aneurysms have been practiced in several centres internationally with excellent outcomes in selected cohorts. The key success in using LA is the advancement in the access techniques and less requirement for conventional open method to advance and deploy the stents through the femoral artery. This literature review aims at examining the current evidences behind the success of LA and whether it is going to be the new wide spread and standard method for anaesthesia in elective or emergency cases of endovascular repair of abdominal aortic aneurysms.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"1 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79639144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000373
J. Marinel-lo, M. Serra-Prat, C. Albuxeich, P. Carreño, J. Lopez-Palencia, E. Palomera, J. Alós
Objective: To assess the safety and efficacy of amniotic membrane (AM) application in venous leg ulcers (VLU). Methodology: Design: non-controlled pre-post clinical trial. A unique AM fragment was placed on the ulcer in strict sterility conditions. Main outcome measures: total healing rate, percentage of ulcer area reduction and diurnal and nocturnal pain assessment. Control visits: at baseline and 1, 2, 3, 4 and 8 weeks after treatment. Results: Ten patients were recruited (79.6 years). 3 weeks after AM implant, pain had completely disappeared and ulcer area had reduced to nearly halved and, 8 weeks after AM implant, ulcer area was reduced in more than 80% and in two thirds of patients the ulcer was completely healed. No relevant side effects were observed. Conclusions: The present study brings new evidence reinforcing the idea that AM dressing is a safety and effective alternative to heal VLU
{"title":"Safety and Efficacy of Amniotic Membrane Implant in Venous Leg Ulcers","authors":"J. Marinel-lo, M. Serra-Prat, C. Albuxeich, P. Carreño, J. Lopez-Palencia, E. Palomera, J. Alós","doi":"10.4172/2329-6925.1000373","DOIUrl":"https://doi.org/10.4172/2329-6925.1000373","url":null,"abstract":"Objective: To assess the safety and efficacy of amniotic membrane (AM) application in venous leg ulcers (VLU). Methodology: Design: non-controlled pre-post clinical trial. A unique AM fragment was placed on the ulcer in strict sterility conditions. Main outcome measures: total healing rate, percentage of ulcer area reduction and diurnal and nocturnal pain assessment. Control visits: at baseline and 1, 2, 3, 4 and 8 weeks after treatment. Results: Ten patients were recruited (79.6 years). 3 weeks after AM implant, pain had completely disappeared and ulcer area had reduced to nearly halved and, 8 weeks after AM implant, ulcer area was reduced in more than 80% and in two thirds of patients the ulcer was completely healed. No relevant side effects were observed. Conclusions: The present study brings new evidence reinforcing the idea that AM dressing is a safety and effective alternative to heal VLU","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"1 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86323432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000369
W. M. Gamal, M. A. Abbas, Amira Mohamed
Background: Diabetic foot (DF) is one of the most widespread type 2 diabetes mellitus “T2DM” complications, it originates from the conjunction of neuropathy and vascular disease. Some reports suggest that amputees might be prone to cognitive decline. Aim of the work: To investigate the cognitive function of DF patients and the relations between it and diabetes complications& comorbidities. Patients and methods: One hundred dementia-free subjects with DF aged >18 were enrolled in the study through the period from March to August 2018 from the Vascular outpatient clinic of Qena University Hospital and only patients whom gave consent have joined the study. The mean age of the study group was 61 years, with 70 males and 30 females, their demographic characters were recorded and medical cognitive tests were applied. Patients have been undergone clinical vascular examination, data on diabetic complications and comorbidities were gathered; (HbA1c) tests were carried out for all patients. Results: The mean Mini-Mental State Examination “MMSE” score of subjects was 24.6 and 40% had global cognitive dysfunction (MMSE ≤ 24). Between elderly subjects (aged ≥ 65), MMSE impairment was linked to amputation, episodic memory impairment was connected to foot amputation and complications. Elderly subjects with HbA1c >7% had elevated odds of psychomotor slowness and abstract reasoning impairment. However, such findings were not present in adult subjects <65 years. Conclusion: Diabetic foot is the severest form of T2DM that causes significant impairment in all cognitive domains. The severity of depression is significantly increased with the intensity of amputation.
{"title":"Study of Cognitive Impairment between Diabetic Foot Patients","authors":"W. M. Gamal, M. A. Abbas, Amira Mohamed","doi":"10.4172/2329-6925.1000369","DOIUrl":"https://doi.org/10.4172/2329-6925.1000369","url":null,"abstract":"Background: Diabetic foot (DF) is one of the most widespread type 2 diabetes mellitus “T2DM” complications, it originates from the conjunction of neuropathy and vascular disease. Some reports suggest that amputees might be prone to cognitive decline. Aim of the work: To investigate the cognitive function of DF patients and the relations between it and diabetes complications& comorbidities. Patients and methods: One hundred dementia-free subjects with DF aged >18 were enrolled in the study through the period from March to August 2018 from the Vascular outpatient clinic of Qena University Hospital and only patients whom gave consent have joined the study. The mean age of the study group was 61 years, with 70 males and 30 females, their demographic characters were recorded and medical cognitive tests were applied. Patients have been undergone clinical vascular examination, data on diabetic complications and comorbidities were gathered; (HbA1c) tests were carried out for all patients. Results: The mean Mini-Mental State Examination “MMSE” score of subjects was 24.6 and 40% had global cognitive dysfunction (MMSE ≤ 24). Between elderly subjects (aged ≥ 65), MMSE impairment was linked to amputation, episodic memory impairment was connected to foot amputation and complications. Elderly subjects with HbA1c >7% had elevated odds of psychomotor slowness and abstract reasoning impairment. However, such findings were not present in adult subjects <65 years. Conclusion: Diabetic foot is the severest form of T2DM that causes significant impairment in all cognitive domains. The severity of depression is significantly increased with the intensity of amputation.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"41 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89120495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-6925.1000368
T. Tran-Thi-Khanh, D. Phan-Thi-Thuy, S. Duong-Quy
Background and objectives: The risk of gastrointestinal bleeding in patients hospitalized with acute myocardial infarction is higher due to antiplatelet and anticoagulant agents along with revascularization. There are limited data about predictors and implications of gastrointestinal bleeding in acute myocardial infarction. Our research aims to investigate the incidence, predictors, clinical outcomes associated with gastrointestinal bleeding in patients with acute myocardial infarction. Patients and methods: Cross sectional study was conducted. All patients diagnosed with acute myocardial infarction at Tam Duc Heart hospital from January 2013 to March 2017 were enrolled. Results: A total of 643 patients with acute myocardial infarction were included (67.2 ± 13.8 years). Gastrointestinal bleeding occurred in 9.5%. Multiple logistic regression analysis demonstrated that female (OR 2.21; CI95%: 1.02- 4.74; p=0.044), pneumonia (OR 2.76; CI95%: 1.25-6.08; p=0.012), impared renal function (OR 4.65; CI95%: 2.08- 10.4; p<0.001) were independent predictors of gastrointestinal bleeding. Gastrointestinal bleeding was significantly associated with prolonged hospital stay (21.8 vs. 9.7 days; p<0.01), increased the need of transfusion (39.4% vs. 3.9%; p<0.001), higher in-hospital mortality (21.3% vs. 7.2%; p<0.01). Conclusion: The rate of gastrointestinal bleeding was 9.5%. Female, pneumonia, impared renal function were independent predictors in patients with acute myocardial infartion.
{"title":"Predictors and Outcomes of Gastrointestinal Bleeding in Patients with Acute Myocardial Infarction","authors":"T. Tran-Thi-Khanh, D. Phan-Thi-Thuy, S. Duong-Quy","doi":"10.4172/2329-6925.1000368","DOIUrl":"https://doi.org/10.4172/2329-6925.1000368","url":null,"abstract":"Background and objectives: The risk of gastrointestinal bleeding in patients hospitalized with acute myocardial infarction is higher due to antiplatelet and anticoagulant agents along with revascularization. There are limited data about predictors and implications of gastrointestinal bleeding in acute myocardial infarction. Our research aims to investigate the incidence, predictors, clinical outcomes associated with gastrointestinal bleeding in patients with acute myocardial infarction. Patients and methods: Cross sectional study was conducted. All patients diagnosed with acute myocardial infarction at Tam Duc Heart hospital from January 2013 to March 2017 were enrolled. Results: A total of 643 patients with acute myocardial infarction were included (67.2 ± 13.8 years). Gastrointestinal bleeding occurred in 9.5%. Multiple logistic regression analysis demonstrated that female (OR 2.21; CI95%: 1.02- 4.74; p=0.044), pneumonia (OR 2.76; CI95%: 1.25-6.08; p=0.012), impared renal function (OR 4.65; CI95%: 2.08- 10.4; p<0.001) were independent predictors of gastrointestinal bleeding. Gastrointestinal bleeding was significantly associated with prolonged hospital stay (21.8 vs. 9.7 days; p<0.01), increased the need of transfusion (39.4% vs. 3.9%; p<0.001), higher in-hospital mortality (21.3% vs. 7.2%; p<0.01). Conclusion: The rate of gastrointestinal bleeding was 9.5%. Female, pneumonia, impared renal function were independent predictors in patients with acute myocardial infartion.","PeriodicalId":17397,"journal":{"name":"Journal of Vascular Medicine & Surgery","volume":"30 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85347187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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