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Hepatic Cyst Infection Following Recurrent Biliary Obstruction in Polycystic Liver Disease. 多囊性肝病复发性胆道梗阻后肝囊肿感染。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.353
Koichiro Miyagawa, Yu Nakano, Akitoshi Yoneda, Masashi Kusanaga, Shinji Oe, Yuichi Honma, Michihiko Shibata, Masaru Harada
An 89-year-old man with polycystic liver disease (PCLD) received uncovered self-expandable metallic stent (SEMS) placement above the papilla for malignant biliary obstruction caused by cholangiocarcinoma. He developed cholangitis ten months later due to SEMS occlusion caused by tumor ingrowth, and 2 plastic biliary stents were placed inside the SEMS across the papilla. Fever and right costal pain appeared two weeks after reintervention. Suspecting hepatic cyst infection based on imaging studies, percutaneous transhepatic cyst drainage was performed. Increased inflammatory cells and the presence of pathogens in the cyst fluid led to a definitive diagnosis of hepatic cyst infection. Following drainage, the hepatic cyst shrank with resolution of the symptoms. SEMS occlusive-related cholangitis or retrograde infection due to duodenal-biliary reflux after reintervention was considered as the cause of the hepatic cyst infection. Careful clinical and imaging evaluation should be performed in patients with PCLD undergone biliary stenting, because cyst infection may occur following stent occlusion or subsequent biliary reintervention.
一例89岁男性多囊性肝病(PCLD)患者,因胆管癌引起的恶性胆道梗阻,在乳头上方放置无盖自膨胀金属支架(SEMS)。10个月后,由于肿瘤向内生长导致SEMS阻塞,患者发生胆管炎,并在SEMS内放置2个塑料胆道支架,穿过乳头。再次干预2周后出现发热和右侧肋痛。基于影像学检查怀疑肝囊肿感染,经皮肝囊肿引流术。囊肿液中炎症细胞的增加和病原体的存在导致肝囊肿感染的明确诊断。引流后,肝囊肿缩小,症状消失。SEMS闭塞性胆管炎或再干预后十二指肠-胆道反流引起的逆行性感染被认为是肝囊肿感染的原因。对于行胆道支架置入术的PCLD患者,应进行仔细的临床和影像学评估,因为在支架闭塞或随后的胆道再介入治疗后可能发生囊肿感染。
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引用次数: 0
[Implementation of Clinical Practice in Adult Nursing (Chronic Care) During the COVID-19 Pandemic: Report on the Development and Implementation of a Training Program for Clinical Shadowing]. [COVID-19大流行期间成人护理(慢性护理)临床实践的实施:临床实习培训计划的制定和实施报告]。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.313
Tomoko Hagiwara, Kyohei Yamaguchi

Before the outbreak of COVID-19, "Clinical Practice in Adult Nursing (Chronic Care)", a professional course to acquire basic nursing practice skills for the care of adult patients with chronic diseases, was conducted on site in the wards of internal medicine, outpatient departments, and the admissions support office for a total of three weeks. Due to the spread of the COVID-19 epidemic, however, clinical practice was carried out online from May 2020, and was resumed on site at our university hospital in October 2020. A restriction was placed on the length of time spent at the hospital for on-site training, referring to the training standards based on our university's new coronavirus response manual, and a training program was developed for hospital ward training, consisting mainly of shadowing practice performed without speaking or coming into contact with patients. In principle, two students were assigned to one patient: one in the morning and the other in the afternoon. In addition, for practicing the acquisition of patient information through conversation and the provision of nursing assistance, the perspectives used in the process of shadowing were clearly defined so that students could maintain active attitudes in clinical practice, and support was provided so that students could have the experience of engaging with patients, using nurses as mediators. In the results, the students evaluated the contents of the prepared assistance based on their own nursing plan in reference to the practice of the nurse as a mediator, and compared that with the assistance practiced by the nurse based on clinical judgment, which contributed to acquiring practical learning supported by the grounds for clinical judgment. However, the students could not experience the process of building supportive relationships and the implementation of nursing skills, which remained an issue.

新冠肺炎疫情暴发前,在内科病房、门诊部和接诊支持办公室现场开展了为期三周的成人慢性病患者护理基本实践技能专业课程《成人护理临床实践(慢性病护理)》。然而,由于新冠肺炎疫情的蔓延,从2020年5月开始在线进行临床实践,并于2020年10月在学校医院现场恢复。参照学校新型冠状病毒应对手册的培训标准,对住院现场培训时间进行了限制,并制定了医院病房培训计划,主要包括不与患者说话或接触的影子实践。原则上,两个学生被分配给一个病人:一个在上午,另一个在下午。此外,在练习通过对话获取患者信息和提供护理协助方面,明确了阴影过程中使用的视角,使学生在临床实践中保持积极的态度,并提供支持,使学生获得与患者接触的体验,以护士为调解人。结果显示,学生参照护士作为调解员的实践,根据自己的护理计划对准备的辅助内容进行评价,并与护士基于临床判断的辅助进行比较,有助于获得临床判断依据支持的实践学习。然而,学生们无法体验到建立支持关系和实施护理技能的过程,这仍然是一个问题。
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引用次数: 0
Capability of Relative Odor Level Monitors to Measure the Odor of Thirdhand Smoke. 相对气味水平监测仪测量三手烟气味的能力。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.269
Mitsuo Hinoue, Kunio Hara, Ying Jiang, Hiroshi Yamato

We investigated the probability of measuring the odor of thirdhand smoke using four odor-measuring monitors and three gas detector tubes. We measured the changes in tobacco odor on paper towels and cloth products over time. The results of the measurements were plotted against time to obtain an exponential approximation curve. The coefficient of x and the R2 values were calculated from this curve. The odor indicated by four types of odor-measuring monitors and three types of gas detector tubes decreased exponentially over time. The curves obtained from all measuring devices had coefficients of ex between -0.001 and -0.021, and R2 values of >0.8. The reproducibility of measuring relative odor levels through all measuring devices was high, suggesting a good capability of measuring thirdhand smoke odor. Two different odor-level standard gases can be used for the calibration of the regression curve for each monitor.

我们研究了使用四台气味测量仪和三根气体检测管测量三手烟气味的可能性。我们测量了纸巾和布制品上烟草气味随时间的变化。测量结果与时间的关系被绘制成指数近似曲线。根据该曲线计算出 x 系数和 R2 值。四种气味测量仪和三种气体检测管显示的气味随时间呈指数下降。所有测量设备得出的曲线的 x 系数在 -0.001 和 -0.021 之间,R2 值大于 0.8。所有测量装置测量相对气味水平的重现性都很高,表明测量三手烟气味的能力很强。每个监测仪可使用两种不同气味水平的标准气体来校准回归曲线。
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引用次数: 0
[Health Effects Caused by Soil Fumigant Chloropicrin, Reduction of Exposure to Chloropicrin, and Alternative Technology of Soil Fumigants]. [土壤熏蒸剂氯丁对健康的影响,减少氯丁暴露和土壤熏蒸剂的替代技术]。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.395
Hiroshi Nagami, Takajiro Suenaga

Pesticides are essentially toxic to living things and are used openly, so it is necessary to monitor them to prevent their adverse effects. We have studied farmers'exposure to pesticides during soil fumigation operations with chloropicrin, and have noted a danger to the farmers in the form of dyspnea. We examined accidents/symptoms of residents from chloropicrin reported by the Ministry of Agriculture, Forestry, and Fishery from 2010 to 2019. Eighty percent of the cause of these manifestations was the failure to cover fumigated soil with plastic film. Symptoms shown by residents included eye pain (91%), sore throat (35%), and headache (14%). The most common film used for covering fumigated soil in Japan is polyethylene. The agricultural technology centers in Japan have studied the use of gas barrier films, and found it possible to decrease the amount of chloropicrin used to 1/3, and leakage into the atmosphere to less than 1/10. This technology has become popular in the production of sweet potatoes in Tokushima Prefecture. Soil disinfection by solar heat has also been studied in Japan. These studies have shown positive advancements in the fertilization of soil and in the control of microbes. Chloropicrin has caused occupational exposure to farmers and environmental exposure to local residents. It is advisable that the technologies mentioned above become common practice.

农药对生物本质上是有毒的,而且是公开使用的,因此有必要对其进行监测,以防止其产生不良影响。我们研究了农民在使用氯丁进行土壤熏蒸作业时对农药的暴露情况,并注意到对农民造成呼吸困难的危险。我们调查了2010年至2019年农林渔业部报告的居民使用氯丁的事故/症状。造成这些现象的百分之八十的原因是没有用塑料膜覆盖熏蒸过的土壤。住院医师表现的症状包括眼痛(91%)、喉咙痛(35%)和头痛(14%)。在日本,覆盖熏蒸土壤最常用的薄膜是聚乙烯。日本的农业技术中心研究了气体屏障膜的使用,发现可以将氯丁的使用量减少到1/3,并将泄漏到大气中的量减少到1/10以下。这项技术在德岛县的红薯生产中很受欢迎。日本也进行了太阳能消毒土壤的研究。这些研究表明,在土壤施肥和微生物控制方面取得了积极进展。氯丁对农民造成职业暴露,对当地居民造成环境暴露。建议上述技术成为普遍做法。
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引用次数: 1
[A Case of Bilateral Medial Medullary Infarction With Heart Appearance Sign]. 双侧内髓梗死伴心脏外观征象1例。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.373
Hirotsugu Ohta, Takeru Umemura, Hirohisa Kondoh, Junkoh Yamamoto

We report a bilateral medial medullary infarction in which diffusion-weighted images revealed a unique configuration: a heart appearance sign. If it is early diagnosed, it might predict a poor outcome. An 85-year-old man developed dysarthria and numbness in his four limbs and was transferred to our hospital. Brain MR diffusion-weighted images revealed a high-intensity lesion in the bilateral medial medulla oblongata -- a heart appearance sign -- and we diagnosed a bilateral medial medullary infarction. Although his symptom changed aggressively for the worse, it finally changed for the better without bulbar paralysis, and he was transferred to another hospital for rehabilitation. When the medial medulla oblongata is supplied by the unilateral control of the anterior spinal artery, its occlusion can cause a bilateral medial medullary infarction.

我们报告一个双侧内侧髓梗死,其中弥散加权图像显示一个独特的配置:心脏外观征象。如果早期诊断,它可能预示着一个糟糕的结果。一位85岁的男性出现构音障碍和四肢麻木,被转移到我们医院。脑MR弥散加权图像显示双侧延髓内高强度病变-心脏外观征象-我们诊断为双侧延髓内梗死。虽然他的症状急剧恶化,但最终好转,没有出现球麻痹,他被转移到另一家医院进行康复治疗。当内延髓由单侧控制的脊髓前动脉供应时,其闭塞可引起双侧内延髓梗死。
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引用次数: 0
[The Japanese Law Regulating Underwater and Caisson Work: Current Issues and Future Developments]. [管理水下和沉箱作业的日本法律:当前问题和未来发展]。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.359
Kiyotaka Kohshi, Yoshitaka Morimatsu, Hideharu Nishikiori, Toshihiro Kondo, Hideki Tamaki, Tatsuya Ishitake

The Japan "Ordinance on Safety and Health of Work under High Pressure", which is the law regulating health conditions for workers under high pressure environments, was amended in 2014. The revised regulations have highlighted other difficulties and new problems, but they have not yet written an appropriate amendment based on the aspect of occupational and environmental health. Health management for occupational divers and caisson workers in accordance with the new regulations has not determined the best approach to reducing related disorders and will cause other legal problems. This paper presents some issues in the new regulations for hyperbaric workers, which directly or indirectly involve occupational health physicians. Health checkups and work limitations should be done in consideration of the occupational characteristics of the undersea and hyperbaric environment. Regular examinations using specific studies are useful to diagnose the early stages of chronic conditions for workers, and are also useful for determining the hiring suitability for hyperbaric workers. Work limitations should be decided by the conditions that induce serious accidents or disorders that result from exposure to hyperbaric environments, and depend on the obstacles for work due to sequelae of decompression sickness. The new regulations need to be properly revised, based on scientific evidence, to include health management for workers in undersea and hyperbaric environments.

日本的《高压下工作安全和健康条例》是规范高压环境下工人健康条件的法律,于2014年进行了修订。修订后的条例强调了其他困难和新问题,但尚未根据职业和环境卫生方面编写适当的修正案。根据新条例对职业潜水员和沉箱工人的健康管理尚未确定减少相关疾病的最佳方法,并将引起其他法律问题。本文介绍了新《高压作业人员管理条例》中直接或间接涉及职业卫生医师的一些问题。应考虑到海底和高压环境的职业特点,进行健康检查和工作限制。使用特定研究的定期检查有助于诊断工人的慢性疾病的早期阶段,也有助于确定雇用高压工人的适用性。工作限制应根据暴露在高压环境中导致严重事故或疾病的情况来决定,并取决于减压病后遗症对工作的阻碍。需要根据科学证据对新条例进行适当修订,以包括对海底和高压环境中工作人员的健康管理。
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引用次数: 0
[Announcement of the 40th Annual Meeting of the UOEH Association of Health Sciences]. [UOEH卫生科学协会第40届年会公告]。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.321
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引用次数: 0
A Case of Pancreatic Neuroendocrine Tumor G3 Which Responded Remarkably to Chemotherapy. 胰腺神经内分泌肿瘤G3化疗疗效显著1例。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.287
Satoru Nebuya, Shinji Oe, Yoshikazu Harada, Yusuke Takeuchi, Akitoshi Yoneda, Yudai Koya, Koichiro Miyagawa, Yuichi Honma, Michihiko Shibata, Masaru Harada

Pancreatic neuroendocrine carcinoma (NEC) as classified in the World Health Organization (WHO) 2010 was reclassified in the WHO 2017 as either neuroendocrine tumor (NET) G3 or NEC. An accurate diagnosis based on the WHO 2017 classification is important in order treating this disease appropriately. We report a case diagnosed as NET G3 that responded remarkably well to treatment with streptozocin. The patient would likely not have received the streptozocin treatment if she had been diagnosed with NEC. The WHO 2017 classification is reasonable for the treatment of advanced pancreatic neuroendocrine neoplasms.

2010年世界卫生组织(WHO)分类的胰腺神经内分泌癌(NEC)在2017年WHO重新分类为神经内分泌肿瘤(NET) G3或NEC。根据世卫组织2017年分类作出准确诊断,对于适当治疗这种疾病至关重要。我们报告一例诊断为NET G3的病例,对链脲菌素治疗反应非常好。如果她被诊断为NEC,病人可能不会接受链脲佐菌素治疗。世卫组织2017年的分类对于晚期胰腺神经内分泌肿瘤的治疗是合理的。
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引用次数: 0
Pre-operative Physical Performance Is Associated With Early Return to Work in Peri-operative Lung Cancer Patients. 围手术期肺癌患者术前体能表现与早期重返工作岗位相关
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.341
Hiroaki Teramatsu, Hiroshi Yamato, Ying Jiang, Hiroaki Kako, Satoshi Kuhara, Ryosuke Ohya, Hideaki Itoh, Koji Kuroda, Yasuyuki Matsushima, Satoru Saeki

Little is known about the factors related to return to work (RTW) in patients with peri-operative lung cancer (LC). This study aimed to investigate whether pre-operative physical performance is associated with early RTW in patients with peri-operative LC. A total of 59 patients who wished to resume work after lung resection surgery were included and were divided into three groups: early RTW (within 14 days after discharge), delayed RTW (within 15-90 days), and non-RTW (failure of RTW within 90 days). The early RTW group had significantly lower scores on the modified Medical Research Council dyspnea scale (mMRC) and significantly higher scores on the Euro Quality of Life 5-Dimension 3-Level (EQ-5D-3L) than the non-RTW group. Multivariate logistic regression analysis showed that EQ-5D-3L scores were significantly associated with early RTW, and mMRC scores and knee extensor strength tended to be associated with early RTW. Better pre-operative quality of life, mild dyspnea, and greater lower limb muscle strength tended to be associated with early RTW in patients with peri-operative LC.

对于围手术期肺癌(LC)患者重返工作岗位(RTW)的相关因素了解甚少。本研究旨在探讨围手术期LC患者术前体能表现是否与早期RTW相关。共纳入59例肺切除术后希望恢复工作的患者,分为早期RTW组(出院后14天内)、延迟RTW组(15-90天内)和非RTW组(90天内RTW失败)。早期RTW组在改良的医学研究委员会呼吸困难量表(mMRC)上的得分显著低于非RTW组,在欧洲生活质量5维3级(EQ-5D-3L)上的得分显著高于非RTW组。多因素logistic回归分析显示,EQ-5D-3L评分与早期RTW显著相关,mMRC评分和膝关节伸肌力量倾向于与早期RTW相关。围手术期LC患者术前生活质量较好、轻度呼吸困难、下肢肌力较强往往与早期RTW相关。
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引用次数: 0
[A Case of Contact Dermatitis Due to Ultrasonography Gel]. 【超声凝胶致接触性皮炎1例】。
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.379
Hitomi Sugino, Yu Sawada

A 60-year-old female had a subcutaneous mass in the B region of the left breast. A needle aspiration cytologic examination revealed class IV, and she was referred to our surgical department for examination and treatment. She underwent an ultrasound echography on bilateral the mammary glands and axillary lymph nodes. Erythematous papules and plaques were revealed on her left breast, left axilla, and in the center of the chest area. The patient was referred to our dermatology department for evaluation of her skin eruption. Histopathological examination revealed the infiltration of lymphocytes and eosinophils in the perivascular of the upper dermis with spongiosis and liquid degeneration in the epidermis. A patch testing showed a positive reaction to ultrasonography gel. Based on the clinical course and examinations, we diagnosed her skin eruption as contact dermatitis due to ultrasonography gel. Her skin eruption improved rapidly by topical application of betamethasone butyrate propionate ointment. Recurrence of her skin eruption could be avoided by the removal of the gel after the ultrasonography examination. Our case report demonstrated to us that contact dermatitis could be prevented by promptly wiping off the ultrasonography gel from the skin after the examination.

60岁女性左乳房B区皮下肿块。针吸细胞学检查显示为IV级,她被转到我的外科检查和治疗。她接受了双侧乳腺和腋窝淋巴结的超声检查。左乳房、左腋窝及胸部中央可见红斑丘疹及斑块。患者被转介到我们的皮肤科评估她的皮肤疹。组织病理学检查显示真皮上部血管周围淋巴细胞和嗜酸性粒细胞浸润,伴有海绵状病变和表皮液体变性。膜片试验显示超声凝胶阳性反应。根据临床过程和检查,我们诊断她的皮肤疹为接触性皮炎。局部应用丁酸丙酸倍他米松软膏后,皮疹迅速好转。超声检查后取出凝胶可避免皮肤复发。我们的病例报告向我们证明,接触性皮炎可以通过在检查后及时擦拭皮肤上的超声凝胶来预防。
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引用次数: 1
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