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Effect of a priming dose of propofol immediately before induction on fentanyl-induced cough: A prospective clinical study 诱发前立即注射异丙酚对芬太尼诱发咳嗽的影响:一项前瞻性临床研究
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194823
D. Sharma, M. Malhotra, V. Singh
Context: It is not uncommon for fentanyl to induce cough at the time of induction. Aims: To evaluate the effect of subhypnotic dose of propofol on the incidence of occurrence and intensity of fentanyl-induced cough (FIC). Settings and Design: This is a prospective, randomized controlled study. Subjects and Methods: A total of 150 patients of the American Society of Anesthesiologists Classes I and II were assigned to one of the two groups: Group A received normal saline as placebo and Group B received low dose propofol (20 mg) before fentanyl given at a dose of 1.5 μg/kg through a peripheral intravenous catheter. The incidence of occurrence and intensity of cough were observed for the two groups. Statistical Analysis Used: One-way ANOVA, Chi-square test, Fisher's exact test, and Mann–Whitney U-test were used for statistical analysis. P<0.05 was considered statistically significant. Results: The incidence of occurrence of FIC was 29.3% and 6.6%, respectively, for placebo and propofol groups (P = 0.0000). Further, there was statistically significant difference between the groups for different grades of intensity (P = 0.032). There were 21% of patients who suffered desaturation and 1.3% chest wall rigidity in placebo group while no such cases were recorded for the propofol group. Conclusions: Subhypnotic dose of propofol can effectively attenuate FIC. It reduces not only the incidence of occurrence but also the intensity of the cough.
背景:芬太尼在诱导时引起咳嗽并不罕见。目的:探讨异丙酚亚催眠剂量对芬太尼致咳嗽(FIC)发生及强度的影响。背景和设计:这是一项前瞻性、随机对照研究。对象和方法:150例美国麻醉师学会I级和II级患者分为两组:A组给予生理盐水作为安慰剂,B组在芬太尼1.5 μg/kg外周静脉导管给药前给予低剂量异丙酚(20 mg)。观察两组患者咳嗽的发生率和强度。统计分析方法:采用单因素方差分析、卡方检验、Fisher精确检验和Mann-Whitney u检验进行统计分析。P<0.05为差异有统计学意义。结果:安慰剂组和异丙酚组FIC的发生率分别为29.3%和6.6% (P = 0.0000)。不同强度组间差异有统计学意义(P = 0.032)。安慰剂组21%的患者出现了去饱和,1.3%的患者出现了胸壁僵硬,而异丙酚组没有出现此类病例。结论:亚催眠剂量异丙酚能有效减轻FIC。它不仅减少了发生的几率,而且还减少了咳嗽的强度。
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引用次数: 0
Management of giant pseudoaneurysm of ascending aorta presenting as mass in neck: Rare complication of cardioplegia needle 以颈部肿块为表现的升主动脉巨大假性动脉瘤的处理:心脏截瘫针的罕见并发症
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194829
S. Mundada, Vaishali P. Mohod, S. Agnihotri
Ascending aortic pseudoaneurysms are rare and occur infrequently from anastomotic dehiscence of suture lines and cannulation sites from previous aortic surgery. It is managed by open surgical approach but carries a high risk of pseudoaneurysm rupture at the time of sternotomy. We describe a successfully managed case of ascending aortic pesudoaneurysm presenting as a pulsatile mass in the neck. Its orifice was located on the lateral wall of the ascending aorta,which was caused by the cardioplegia cannula inserted during a previous cardiac surgery. We also summarize the anesthetic challenges and complications of such a case.
升主动脉假性动脉瘤是一种罕见且罕见的动脉瘤,发生于吻合口缝合线破裂和先前主动脉手术的插管部位。它是由开放手术方法,但在胸骨切开时假性动脉瘤破裂的风险很高。我们描述一个成功管理的病例升主动脉伪动脉瘤表现为颈部搏动肿块。它的开口位于升主动脉的侧壁,这是由于在以前的心脏手术中插入心脏截瘫套管造成的。我们还总结了这种情况下的麻醉挑战和并发症。
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引用次数: 0
BERAM flap to the rescue; perioperative journey from er to or to recovery in a three-year-old child having type 3c compound fracture with vascular involvement BERAM襟翼救援;3岁儿童3c型复合骨折伴血管受累的围手术期过程
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194827
Ravichandran Narayanan, S. Patil
Systematic approach to a paediatric trauma victim who has sustained life threatening injuries calls for good pre-hospital care, triaging in the emergency room and effective management consisting of primary survey along with skilled resuscitation followed by secondary survey. After stabilization, it is essential to know the severity of injury and soft tissue defect by vigilant clinical examination, coupled with assessment by established scoring systems, such as GANGA and MESS, in order to plan further management. Recent guidelines in polytrauma management stress on initial damage control surgery for achieving haemostasis and debridement, followed by definitive reconstructive procedure. The procedure involves essential management of type 3c compound fracture with vascular involvement by damage control surgery along with vascular repair by saphenous graft followed by unique method of BERAM flap in continuity with Lattismus dorsi myocutaneous flap subsequently. Because of its role in hemodynamic stability and regional blood flow, anaesthesia is an important determining factor in the success of microvascular free flap surgeries. Stabilizing haemodynamic and achieving normal metabolic and biochemical parameters is essential. Our case report is aimed at reviewing the relevant aspects of anaesthetic practice in a procedure involving microvascular flaps.
对持续危及生命的伤害的儿科创伤受害者采取系统的方法需要良好的院前护理,在急诊室进行分诊,并进行有效的管理,包括初级调查以及熟练的复苏,然后是二级调查。稳定后,必须通过警惕的临床检查了解损伤和软组织缺损的严重程度,并结合已建立的评分系统(如GANGA和MESS)进行评估,以便计划进一步的治疗。最近的多处创伤治疗指南强调最初的损伤控制手术,以达到止血和清创,然后进行最终的重建手术。该手术包括通过损伤控制手术和隐静脉移植修复血管,然后采用独特的BERAM皮瓣与背阔肌肌皮瓣连续的方法治疗伴有血管受损伤的3c型复合骨折。由于麻醉对血流动力学稳定性和局部血流的影响,麻醉是微血管游离皮瓣手术成功的重要决定因素。稳定血液动力学和达到正常的代谢和生化参数是必不可少的。我们的病例报告旨在回顾涉及微血管皮瓣的手术过程中麻醉实践的相关方面。
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引用次数: 0
Anesthetic management of a case of robinow syndrome 1例robinow综合征的麻醉处理
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194824
Jagadish B Alur, Madhuri S. Kurdi, P. Sindhu, R. Ranjana
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引用次数: 0
Perioperative anesthetic management of placenta percreta for emergency cesarean surgery 剖宫产急诊手术中胰胎盘的围手术期麻醉处理
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194828
S. Govindswamy, A. M. Shamanna, Asha Harave Liganna
Placenta percreta is one of the most dangerous conditions that eventually result in maternal mortality. A young female with placenta percreta presented for fetal distress. Investigations revealed placenta invading entire abdominal wall, extending up to the urinary bladder and surrounding intestine. Surgery planned was extraction of fetus, leaving placenta in situ and hysterectomy at a later date, once placental vascularity is decreased. The patient was given spinal anesthesia which was later converted to general anesthesia. The patient was monitored for saturation, noninvasive blood pressure (BP), continuous electrocardiography, invasive BP, central venous pressure, urinary output, and temperature. Vitals were maintained within + 20% of the baseline. Healthy fetus was extracted, later followed by placental bed bleeding with massive bleeding of around 3500–4000 mL blood. It was managed with fluids, blood, pressure mops kept in the uterus, and placenta kept in the uterus. The patient was shifted to intensive care unit with elective ventilation. Postoperative day 3, the patient was taken for cesarean hysterectomy. The patient underwent hysterectomy after bilateral internal iliac artery ligation, repair of the bladder wall, and bilateral stenting of ureters. Bleeding of around 1500–2000 mL of blood was managed with fluids and blood. Postoperatively, the patient was managed in the intensive care unit for three days and was discharged from the hospital with a healthy baby without any complications. Antenatal recognition of placenta percreta and multidisciplinary approach by a team of experienced obstetricians, anesthesiologists, nurses, interventional radiologists, neonatologists, and urologists, as well as a blood bank, would decrease blood loss, reduce serious complications, and ensure favorable outcomes. We do here present a case of perioperative management of placenta excreta managed successfully.
percreta是最危险的情况之一,最终会导致产妇死亡。一个年轻的女性与胎盘percreta提出胎儿窘迫。检查发现胎盘侵入整个腹壁,延伸到膀胱和周围的肠道。手术计划是取出胎儿,将胎盘留在原位,并在晚些时候切除子宫,一旦胎盘血管减少。病人先予脊髓麻醉,后转为全身麻醉。监测患者饱和度、无创血压(BP)、连续心电图、有创血压、中心静脉压、尿量和体温。生命体征维持在基线的+ 20%以内。取出健康胎儿,随后出现胎盘床出血,大出血约3500-4000 mL。我们用液体,血液,子宫内的压力拖把和子宫内的胎盘来处理。患者被转移到重症监护病房,并进行选择性通气。术后第3天,行剖宫产子宫切除术。患者于双侧髂内动脉结扎、膀胱壁修复及双侧输尿管支架置入术后行子宫切除术。出血约1500-2000毫升,用液体和血液处理。术后,患者在重症监护室接受了3天的治疗,出院时婴儿健康,没有任何并发症。由经验丰富的产科医生、麻醉科医生、护士、介入放射科医生、新生儿科医生、泌尿科医生以及血库组成的团队对胎盘的产前识别和多学科方法将减少失血,减少严重并发症,并确保良好的预后。我们在此报告一例成功处理胎盘排泄物的围手术期处理。
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引用次数: 0
Silicon airflow prosthetic device after laryngectomy: A clinical trial 喉切除术后硅气流假体装置的临床试验
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194822
Deepak Sharma, Roma Goswami, Gurleen Arora, Pulkit Jain, Sanjay Kumar
Context: Tracheostoma stenosis is a common problem after laryngectomy. Stenosis of trachea stoma leads to respiratory complications. Preservation of stoma patency by implanting a silicon prosthetic device in tracheal stoma could affect the outcome in these situations. Aims: To evaluate tracheal stoma patency in postlarngectomy patients with the silicon prosthetic device. Settings and Design: This is a case series of seven patients who received the device. Materials and Methods: Seven adult patients American Society of Anesthesiologists Grade IV who had undergone laryngectomy for carcinoma larynx received a silicon airflow prosthetic device which was devised for each patient in the prosthodontic laboratory. All the patients were followed at 3 and 6 months to observe the efficiency and potency of device. Results: The average stoma size and average peak expiratory flow 25-75% in litres/sec at first patient visit, 3 and 6 months after receiving the device was 13.42 ± 0.71, 12.55 ± 0.82, 12.7 ± 0.92 mm and 3.08 ± 0.19, 3.10 ± 0.13, 2.89 ± 0.15 mm, respectively. Conclusions: The silicon airflow prosthetic device continued to maintain uninterrupted airflow and prevented tracheal stoma stenosis which encouraged us to place it for longer time after laryngectomy without any eventuality.
背景:气管瘘狭窄是喉切除术后常见的问题。气管造口狭窄可导致呼吸系统并发症。在这些情况下,通过在气管造口植入硅假体装置来保持气道通畅可能会影响结果。目的:评价硅胶假体在大气管切除术后气管吻合通畅的效果。设置和设计:这是一个由7名接受该设备的患者组成的病例系列。材料与方法:7例因喉癌行喉部切除术的美国麻醉医师学会四级患者在修复实验室接受了为每位患者设计的硅气流假体装置。随访3个月和6个月,观察装置的疗效和效力。结果:患者首次就诊时、术后3个月和6个月的平均造口大小和平均呼气峰流量25 ~ 75%(升/秒)分别为13.42±0.71、12.55±0.82、12.7±0.92 mm和3.08±0.19、3.10±0.13、2.89±0.15 mm。结论:硅气流假体继续保持不间断的气流,防止气管造口狭窄,使我们在喉切除术后放置更长的时间,没有任何意外。
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引用次数: 0
Developing protocols for administering anesthesia 制定麻醉方案
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194821
M. Chakravarthy, Keshava Reddy, Jayaprakash Krishnamoorthy, Simha Rajathadri, P. Motiani, Deepak Kavarganahalli, Ashokananda Devanahalli, A. Prashanth, Geetha Muniraju, D. Sheshadri, Mohan Gowda, Antony George
The industrial sector especially the aviation industry has shown the world that by using check lists and protocols, disasters could be prevented. It is now a common practice in many fields to establish protocols to standardize the practices. Such standardization makes the processes similar despite various users practicing the procedure. Although in anesthesia, there are several guidelines suggested by bodies such as the American society of anesthesiologists and Indian society of anaesthetists, strict protocols are not available even for the commonly undertaken procedures. Anesthesia is akin in many respects to flying an aircraft. The induction of anesthesia compared to take off of an aircraft, maintenance to cruising and extubation to landing. It was therefore thought that anesthesia similar to aircraft flying could be made safer by using protocols and checklists. However it may take a while for the practice of anesthesia to get to the “6 Sigma” safety that the airline industry currently enjoys. It is our effort to standardize the commonly performed surgeries at our institution. “The protocols in Anesthesia” emerged as a result of the back breaking work of the consultants in the department of anesthesia. The intention of this effort was to standardize the practice of anesthesia in our institution and to showcase the benefits of such standardization. It is hoped that other institution interested in standardizing their practice could formulate their own protocols. It is also desirable that a “copy and paste” of other protocols in unlikely to benefit the end users. The authors wish to bring forth the point that customized protocols should emerge with the efforts of the users themselves. It becomes more pertinent to suit one's protocol to the prevailing infrastructure, availability of therapeutic agents and economic conditions. The authors sincerely hope this endeavour might stimulate others to put their systems in place, if not pre-existing
工业部门,特别是航空业已经向世界表明,通过使用检查清单和协议,可以预防灾难。现在在许多领域建立协议来规范实践是一种常见的做法。这种标准化使得过程相似,尽管不同的用户都在实践这个过程。尽管在麻醉方面,美国麻醉师协会和印度麻醉师协会等机构提出了一些指导方针,但即使是通常进行的手术,也没有严格的规程。麻醉在很多方面类似于驾驶飞机。将麻醉的诱导比作飞机起飞,维护到巡航,拔管到着陆。因此,人们认为,通过使用协议和清单,可以使麻醉类似于飞机飞行,从而变得更安全。然而,麻醉的实践可能需要一段时间才能达到航空业目前享有的“6西格玛”安全性。我们努力使我们机构的常见手术标准化。《麻醉规程》是麻醉科顾问们辛苦工作的结果。这项工作的目的是使我们机构的麻醉实践标准化,并展示这种标准化的好处。希望其他有兴趣规范其实践的机构可以制定自己的协议。对其他协议的“复制粘贴”不太可能使最终用户受益,这也是可取的。作者希望提出的观点是,定制协议应该在用户自己的努力下出现。更重要的是,要使自己的治疗方案适应当前的基础设施、治疗药物的可用性和经济条件。作者真诚地希望,这一努力可能会刺激其他人将他们的系统(如果不是预先存在的)落实到位
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引用次数: 0
Deliberate controlled hypotension in functional endoscopic sinus surgeries: A comparative study between nitroglycerin and esmolol 功能性内窥镜鼻窦手术中故意控制低血压:硝酸甘油与艾司洛尔的比较研究
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194820
T. Raghavendra, N. Yoganarasimha, A. Shivakumar, M. Radha
Background: Functional endoscopic sinus surgery (FESS) enjoys the privilege of being a minimally invasive intervention for nasal disorders. Intraoperative bleeding is the major problem in these endoscopic surgeries. Excessive bleeding impairs operative visibility, prolongs the duration of surgery and anesthesia, and increases the risk of complications. Controlled hypotension is a method wherein the arterial blood pressure is lowered in a deliberate but predictable manner to reduce the intraoperative bleeding and enhance the surgical field visibility. Aim: The aim of this study was to compare the mean change in heart rate (HR), systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), surgical bleeding, and duration of hypotensive anesthesia caused by nitroglycerin (NTG) or esmolol (ESM), when performing FESS. Materials and Methods: Sixty patients of American Society of Anesthesiologists I and II undergoing FESS under general anesthesia were divided into two groups– the NTG and the ESM group. Vitals were recorded at regular intervals. Hemorrhage was estimated by volumetric and gravimetric estimation. Visibility of the surgical field was rated by the surgeon Fromme et al, with 0 being the driest and 5 making surgery impossible. Results: Intraoperative HR, surgical bleeding, and duration were less in the ESM group. Visibility was much superior in this group too. Conclusions: Both drugs are safe and effective in providing optimal operating conditions, but ESM is superior because it provides superior surgical dryness at higher MAPs and reduces the surgical blood loss and duration more than NTG. Absence of reflex tachycardia was the added advantage of ESM over NTG.
背景:功能性内窥镜鼻窦手术(FESS)享有对鼻部疾病进行微创干预的特权。术中出血是内窥镜手术的主要问题。过多的出血会降低手术的可见度,延长手术和麻醉的时间,并增加并发症的风险。控制性低血压是一种通过有意但可预测的方式降低动脉血压以减少术中出血和提高手术视野可见度的方法。目的:本研究的目的是比较实施FESS时硝酸甘油(NTG)或艾司洛尔(ESM)引起的心率(HR)、收缩压、舒张压、平均动脉压(MAP)、手术出血和低血压麻醉持续时间的平均变化。材料与方法:将60例全麻下行FESS的美国麻醉学会I、II分会患者分为NTG组和ESM组。定期记录生命体征。通过体积和重量估计出血。手术视野的可见度由外科医生Fromme等人评定,0表示最干燥,5表示无法手术。结果:ESM组术中HR、术中出血量、持续时间均明显减少。这一组的能见度也高得多。结论:两种药物在提供最佳手术条件方面都是安全有效的,但ESM优于NTG,因为ESM在较高map下提供更好的手术干燥度,并且比NTG更能减少手术失血量和手术时间。无反射性心动过速是ESM优于NTG的另一个优点。
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引用次数: 1
Anesthetic management of a patient with thoracolumbar kyphoscoliosis coming for emergency endoscopic retrograde cholangiopancreatography and interval laparoscopic cholecystectomy 胸腰椎后凸患者急诊内镜逆行胆管造影和间歇腹腔镜胆囊切除术的麻醉处理
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194825
S. Pandith, Anindita Mukherjee, C. Santosh, B. Ravindra, M. Joshi
We describe a patient with postpoliomyelitis residual paralysis with thoracolumbar kyphoscoliosis who presented for an emergency endoscopic retrograde cholangiopancreatography and interval laparoscopic cholecystectomy. This case report emphasizes on the adequate perioperative optimization and the meticulous anesthetic management of a long-standing kyphoscoliotic patient with respiratory compromise.
我们描述了一例脊髓灰质炎后残余性麻痹伴胸腰椎后凸的患者,他接受了紧急内窥镜逆行胆管胰胆管造影和间歇腹腔镜胆囊切除术。本病例报告强调充分的围手术期优化和细致的麻醉管理长期脊柱后凸患者呼吸损害。
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引用次数: 1
Effect of increase in ph of local anaesthetics on quality of epidural anesthesia 局麻药ph值升高对硬膜外麻醉质量的影响
Pub Date : 2016-04-01 DOI: 10.4103/2394-6954.194826
A. Bagle, S. Deshpande, Nagnath L Garthe
Background: The most persistent criticisms for epidural analgesia for surgery are the latency of onset and marginal intensity of sensory and motor block, so clinical trials were carried out to find out a method to decrease the latency of onset of epidural block. The present study was carried out to determine the effect of increasing pH of 2% lignocaine hydrochloride with adrenaline (1:200000) and 0.5% bupivacaine hydrochloride by addition of sodium bicarbonate administered for epidural anesthesia in inguinal herniorrhaphy. Methods: Eighty male patients aged 18–60 years physical status American Society of Anesthesiology I and II posted for inguinal herniorrhaphy, were enrolled in this study. After placing epidural catheter in epidural space at L3–L4, test dose of 2% lignocaine with adrenaline 3ml was given. After making patient supine, epidural dose is given with local anesthetic according to the group. Group I - 15 ml of 2% lignocaine hydrochloride with adrenaline (1:200000) +0.5 ml normal saline (pH 3.58), Group II - 15 ml of 2% lignocaine hydrochloride with adrenaline (1:200000) +0.5 ml of 7.5% (w/v) sodium bicarbonate (pH 6.78), Group III - 15 ml of 0.5% bupivacaine hydrochloride (pH 5.5) and Group IV - 15 ml of 0.5% bupivacaine hydrochloride + 0.1 ml of 7.5% (w/v) sodium bicarbonate (pH 7.5). In Groups II and IV, pH of solution was increased by addition of sodium bicarbonate. All patients were monitored for the onset of sensory and motor block, intensity of sensory and motor block, highest level of analgesia, duration of sensory and motor blockade, and effects on cardiovascular and respiratory parameters. Results: Onset of sensory and motor block was significantly faster in study Groups (II and IV) as compared to control Groups (I and III). Intensity of block even duration of block was significantly better in pH adjusted group. Conclusion: Increase in pH of local anesthetic solutions used in epidural blockade improves the quality of epidural block.
背景:对手术硬膜外镇痛最持久的批评是发病潜伏期和感觉、运动阻滞的边际强度,因此开展临床试验,寻找降低硬膜外阻滞发病潜伏期的方法。本研究旨在探讨2%盐酸利多卡因加肾上腺素(1:20000)和0.5%盐酸布比卡因加碳酸氢钠在硬膜外麻醉中对腹股沟疝修补术的影响。方法:选取80例年龄18 ~ 60岁,体格符合美国麻醉学学会I、II分会腹股沟疝修补术的男性患者作为研究对象。在L3-L4硬膜外腔放置硬膜外导管后,给予2%利多卡因加肾上腺素3ml试验剂量。病人仰卧后,按组给予硬膜外剂量加局麻。I组- 2%盐酸利多卡因加肾上腺素(1:20万)15 ml +生理盐水0.5 ml (pH 3.58), II组- 2%盐酸利多卡因加肾上腺素(1:20万)15 ml + 7.5% (w/v)碳酸氢钠0.5 ml (pH 6.78), III组- 0.5%盐酸布比卡因15 ml (pH 5.5)和IV组- 0.5%盐酸布比卡因15 ml + 7.5% (w/v)碳酸氢钠0.1 ml (pH 7.5)。在第二组和第四组中,通过添加碳酸氢钠提高溶液的pH值。监测所有患者感觉和运动阻滞的发生、感觉和运动阻滞的强度、最高镇痛水平、感觉和运动阻滞的持续时间以及对心血管和呼吸参数的影响。结果:与对照组(I和III)相比,研究组(II和IV)感觉和运动阻滞的发生明显更快,pH调节组阻滞的强度和持续时间明显更好。结论:提高局麻溶液的pH值可提高硬膜外阻滞的质量。
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引用次数: 2
期刊
Karnataka Anaesthesia Journal
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