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Carotid body paraganglioma excision: Anesthetic challenges 颈动脉体副神经节瘤切除术:麻醉挑战
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190775
Narayansa Irkal Jewarlal, M. Rajaseker, V. S. Reddy, V. Devika, A. Bhardwaj
Carotid body paraganglioma (CBP) is a rare tumour which arises from chemoreceptor cells of the carotid body situated at the bifurcation of common carotid artery. Most commonly these tumours are benign, however, 5-7% of tumours may turn out as malignant; hence, excision is the rule. Anesthesia for excision poses numerous challenges, as these tumours are highly vascular, sense pH, arterial oxygen tension; may secrete catecholamine or serotonin, generally adhere to the carotid artery and accompanied with a perioperative morbidity of 20-40%. Anesthesia managed successful for excision of a CBP Shamblin Group II tumour avoiding invasive monitoring hence reported.
颈动脉体副神经节瘤(CBP)是一种罕见的肿瘤,起源于颈总动脉分叉处的颈动脉体的化学受体细胞。大多数肿瘤是良性的,然而,5-7%的肿瘤可能变成恶性的;因此,切除是规则。麻醉切除带来了许多挑战,因为这些肿瘤是高度血管化的,感觉pH值,动脉氧张力;可分泌儿茶酚胺或血清素,一般粘附于颈动脉,围手术期发病率为20-40%。麻醉成功切除CBP Shamblin II组肿瘤,避免了侵入性监测,因此报告。
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引用次数: 0
A comparative study of palonosetron versus palonosetron and dexamethasone for the prevention of postoperative nausea and vomiting in subjects undergoing laparoscopic surgeries: A randomized double-blind control study 帕洛诺司琼与帕洛诺司琼联合地塞米松预防腹腔镜手术患者术后恶心呕吐的比较研究:一项随机双盲对照研究
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190770
Aastha Srivastava, K. Raghavendra, Leena H. Parate
Background: Palonosetron is an effective antiemetic that can be used for treating postoperative nausea vomiting which is a major problem in laparoscopic surgeries. Aims: The aim of this study was to find out whether addition of dexamethasone to palonosetron would be more effective than palonosetron alone in prevention of this problem in patients undergoing laparoscopic surgeries. Settings and Design: This study was conducted as a double blind study in MS Ramaiah hospital, Bangalore. Materials and Methods: Ninety patients with ASA grade 1 and 2 between 20-60 years of age undergoing elective laparoscopic surgery under general anaesthesia were randomised into two groups of 45 patients each. Group-P received 0.075 mg of palonosetron and Group-P+D received the same dose of palonosetron and 8 mg of dexamethasone before induction. The number of complete responders along with four point nausea and vomiting scores were recorded at 2, 6, 24, 48 hours post-operatively. Statistical Analysis Used: Difference in the number of complete responders in each of the groups were tested to be of statistical significance through Chi square test of significance. P value <0.05 was considered as statistically significant. t-test was used for categorical data assessment. Results: Complete responders recorded in group P+D were 34 (75.5%) and in group P were 35 (77.7%). Three patients in group P+D (6.7%) and 4 patients in group P (8.9%) required rescue anti-emetics. The P value obtained was 0.694 (>0.05) and hence not statistically significant. Conclusion: The addition of dexamethasone to palonosetron does not offer an added advantage over the usage of palonosetron alone as a single drug.
背景:帕洛诺司琼是一种有效的止吐药,可用于治疗术后恶心呕吐,这是腹腔镜手术的主要问题。目的:本研究的目的是了解在腹腔镜手术患者中,在帕洛诺司琼的基础上加入地塞米松是否比单独使用帕洛诺司琼更有效地预防这一问题。背景和设计:本研究在班加罗尔MS Ramaiah医院进行双盲研究。材料和方法:90例年龄在20-60岁之间的ASA 1级和2级患者在全身麻醉下行选择性腹腔镜手术,随机分为两组,每组45例。p组诱导前给予帕洛诺司琼0.075 mg, p +D组诱导前给予同等剂量帕洛诺司琼加地塞米松8mg。分别于术后2、6、24、48小时记录完全缓解人数及4点恶心呕吐评分。统计学分析方法:采用卡方显著性检验检验各组完全应答数的差异是否具有统计学意义。P值0.05),因此无统计学意义。结论:在帕洛诺司琼中加入地塞米松并不比单独使用帕洛诺司琼有额外的优势。
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引用次数: 6
Amniotic fluid embolism during emergency hysterotomy 紧急剖宫产时羊水栓塞
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190774
A. Bhuva, A. Shetti, V. Kharde, D. Divekar
The most common obstetric surgeries performed in India are cesarean section. Unwillingness to undergo normal delivery, unfavorable anatomy, previous cesarean section, and pregnancy-induced hypertension are common indications to name. Although pregnancy is a natural process, many physiological changes occur in maternal health. Pregnant lady is at risk to develop pregnancy-related complications. Amniotic fluid embolism is one of the life-threatening complications that is seen during delivery.
印度最常见的产科手术是剖宫产。不愿正常分娩、解剖不良、既往剖宫产、妊娠高血压是常见的指征。虽然怀孕是一个自然过程,但在产妇保健过程中会发生许多生理变化。孕妇有发生妊娠相关并发症的风险。羊水栓塞是分娩过程中常见的危及生命的并发症之一。
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引用次数: 0
Apnoea during Spinal Anesthesia: A Medication Error 脊髓麻醉期间的呼吸暂停:一个药物错误
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190776
B. Paliwal, Anamika Purohit, P. Sethi
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引用次数: 1
Comparative study of granisetron versus pethidine for the prevention of perioperative shivering under spinal Anesthesia 格拉司琼与哌啶预防脊髓麻醉围手术期寒战的比较研究
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190769
Savitri D. Kabade, Y. Venkatesh, S. Karthik, Vikas Kumar
Aims: Shivering, the "big little problem," has an incidence of 19-33% following spinal anesthesia. Recently, studies showed the involvement of serotonergic system in the control of postanesthetic shivering. Pharmacological management includes opioids (pethidine) and nonopioids like 5-HT3 receptor antagonists (ondansetron and granisetron). Pethidine which is considered as a time-tested drug for control of shivering can have adverse effects such as respiratory depression, nausea, and vomiting. This study was performed to compare the effect of prophylactic granisetron versus pethidine in prevention of perioperative shivering in patients under spinal anesthesia. Settings and Design: A prospective randomized, double blinded study was conducted on 60 patients of ASA I and II physical status aged between 20-50 years scheduled for elective lower abdominal surgeries under spinal anesthesia. Subjects and Methods: After obtaining ethical committee clearance and patient consent, sixty American Statistical Association Grade I and II patients, aged 20-50 years scheduled for elective lower abdominal surgeries under spinal anesthesia were recruited for a randomized double-blinded study divided into Group G and Group P and received intravenous (IV) granisetron 40 mcg/kg and pethidine 0.4 mg/kg, respectively. Perioperatively, vitals and core temperature were monitored and shivering was assessed using 5-item scale once in every 15 min up to 6 h. Statistical Analysis: The results were analysed using Statistical Package for Social Science software. Results: Of the sixty patients we studied, the demographic profile between the two groups was comparable. Six patients had shivering in each group. The mean temperature at which patient developed shivering was 36.31°C in Group G and 35.85°C in Group P. The mean time of onset for shivering to occur in Group G was 95 min and in Group P was 65 min. None of the patients received rescue drug. Patients in both the groups were hemodynamically stable. Conclusions: Prophylactic granisetron 40 μg/kg IV is as effective as pethidine 0.4 mg/kg IV in preventing perioperative shivering following spinal anesthesia and also reduces the need of antiemetics.
目的:脊髓麻醉后发抖的“大问题小问题”发生率为19-33%。近年来的研究表明,血清素能系统参与了麻醉后寒战的控制。药物管理包括阿片类药物(哌啶)和非阿片类药物,如5-HT3受体拮抗剂(昂丹司琼和格拉司琼)。哌替啶被认为是一种久经考验的控制颤抖的药物,但它会产生不良反应,如呼吸抑制、恶心和呕吐。本研究的目的是比较预防性格拉司琼与哌啶预防脊髓麻醉患者围手术期寒战的效果。背景与设计:本研究是一项前瞻性随机双盲研究,研究对象为60例年龄在20-50岁的ASA I和II级身体状况的患者,计划在脊髓麻醉下择期进行下腹部手术。对象和方法:经伦理委员会批准和患者同意,招募60例年龄在20-50岁、计划在脊髓麻醉下择期行下腹手术的美国统计协会一级和二级患者进行随机双盲研究,分为G组和P组,分别静脉注射格拉司琼40 mcg/kg和哌啶0.4 mg/kg。围手术期监测生命体征和核心体温,每15分钟至6小时用5项量表评估一次寒战。统计分析:使用Statistical Package for Social Science软件对结果进行分析。结果:在我们研究的60例患者中,两组之间的人口统计学特征具有可比性。每组有6名患者发抖。G组患者发生寒战的平均温度为36.31℃,P组患者发生寒战的平均时间为35.85℃。G组患者发生寒战的平均时间为95 min, P组患者发生寒战的平均时间为65 min。两组患者血流动力学稳定。结论:预防性格拉司琼40 μg/kg IV与哌啶0.4 mg/kg IV预防脊髓麻醉后围手术期寒战的效果相同,且可减少止吐药的使用。
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引用次数: 10
A randomized comparative study between Airtraq and Mccoy for intubation in patients with cervical spine injury Airtraq和Mccoy在颈椎损伤患者插管中的随机比较研究
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190768
S. Moningi, D. Kulkarni, G. Ramachandran, A. Aluri, Sudheer Kumar Atluri, Anshul Yadav
Background: This study was done to compare Airtraq and McCoy for intubation characteristics and hemodynamic parameters following endotracheal intubation in patients undergoing anterior cervical discectomy and fusion (ACDF) surgery. Materials and Methods: After Institutional Ethical Committee approval, a prospective randomized comparative study was designed on forty American Society of Anesthesiologists I and II patients involving single level ACDF surgery. Following standard anesthesia protocol and manual in-line stabilization applied along with a cervical collar or pin traction for immobilization, tracheal intubation was performed either with Airtraq or McCoy. The time taken for intubation, intubation difficulty score (IDS), comfort grading, and hemodynamic parameters were noted following intubation. The categorical data were compared using Chi-square test and the continuous variables were compared between the groups using paired sample t-test. Repeated ANOVA was tested for hemodynamic data at each measurement time point and Tukey post hoc was used for within the group comparisons at different timings following intubation. Results: The mean intubation time was 24.41 ± 14.8 s in Airtraq group (Group A) which was statistically significant compared to McCoy group (Group M) 38.96 ± 15.55 s (P = 0.001). The IDS and comfort grading was statistically significant in Group A compared to Group M. The changes in hemodynamic vitals following intubation were comparable in both the groups. Conclusion: Airtraq improves the grade of glottic visualization with minimal assistance. It also minimized the time taken for intubation had stable hemodynamics with increased comfort to the anesthetist.
背景:本研究比较了Airtraq和McCoy在行前路颈椎间盘切除术和融合(ACDF)手术患者气管插管后的插管特征和血流动力学参数。材料和方法:经机构伦理委员会批准,对40例美国麻醉师学会I和II级患者进行单节段ACDF手术设计了一项前瞻性随机比较研究。遵循标准麻醉方案和手动在线稳定,并使用颈套或引针牵引固定,气管插管使用Airtraq或McCoy。插管后记录插管时间、插管困难评分(IDS)、舒适度评分和血流动力学参数。分类资料比较采用卡方检验,组间连续变量比较采用配对样本t检验。在每个测量时间点对血流动力学数据进行重复方差分析,并在插管后不同时间点对组内比较使用随机方差分析。结果:Airtraq组(A组)平均插管时间为24.41±14.8 s,与McCoy组(M组)38.96±15.55 s相比,差异有统计学意义(P = 0.001)。与m组相比,A组的IDS和舒适度评分具有统计学意义。两组插管后血液动力学指标的变化具有可比性。结论:Airtraq在最小辅助下提高了声门显像的等级。它还减少了插管时间,稳定了血流动力学,增加了麻醉师的舒适度。
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引用次数: 2
Limb ischemia after central venous cannulation: Is the cannulation to blame? 中心静脉置管后肢体缺血:是置管造成的吗?
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190778
R. Ranjana
A 65-year-old woman underwent right subclavian venous cannulation in the Intensive Care unit. Within a few hours following the cannulation, ischemic changes were noted in the right upper limb. A misplaced central venous catheter was suspected as the cause of the ischemia. However, a color Doppler study revealed right axillary artery thrombosis. She was put on antiplatelet therapy. Upper limb vascular complications can occur after central venous catheterization due to various causes. Timely investigations and management can help at such critical times.
一位65岁的女性在重症监护室接受了右锁骨下静脉插管。插管后数小时内,右上肢出现缺血性改变。中心静脉导管放错位置被怀疑是缺血的原因。然而,彩色多普勒检查显示右腋窝动脉血栓形成。她接受了抗血小板治疗。中心静脉置管后上肢血管并发症可由多种原因引起。在这种关键时刻,及时的调查和管理可以有所帮助。
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引用次数: 0
Transient vision loss in transurethral resection of prostate syndrome 经尿道前列腺切除术后短暂性视力丧失
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190773
Kempachary, T. Raghavendra, D. Vinutha, Chaithra Gundulpet Vasanth, K. Prasannan
We had an unusual experience of patient developing transient loss of vision following transurethral resection of prostate. Various pathophysiological changes contributing the vision loss during transurethral resection of the prostate has been discussed. The patient recovered his vision fully after therapeutic interventions. This paper discusses the possible etiologies for the transient vision loss and treatment of same.
我们有一个不寻常的经验,病人发展一过性视力丧失后经尿道前列腺切除术。各种病理生理变化,促进视力丧失在经尿道前列腺切除术已讨论。病人经过治疗后视力完全恢复。本文讨论了短暂性视力丧失的可能病因及治疗方法。
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引用次数: 1
Segmental epidural Anesthesia in an obese patient undergoing percutaneous Nephrolithotomy in prone position 肥胖症患者俯卧位经皮肾镜取石术的段性硬膜外麻醉
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190771
Tasneem S Dhansura, Aizaz Mohammed
The increasing incidence of obesity is a crisis in health care where these patients are increasingly being anesthetized for nonbariatric surgery. Anesthetizing an obese patient is a challenge and more so if surgery is to be done in prone position. We would like to present a patient, a 59-year-old male with body mass index of 45 (weight: 145 kg; height: 178 cm; abdominal girth: 135 cm) with a history of diabetes mellitus, hypertension, and chronic obstructive pulmonary disease since 10 years posted for a left-sided percutaneous nephrolithotomy. Successfully managed under epidural anesthesia and operated in the prone position.
肥胖发病率的增加是医疗保健的危机,这些患者越来越多地接受非减肥手术麻醉。麻醉一个肥胖的病人是一个挑战,如果手术是做俯卧位更是如此。我们报告一位59岁男性患者,身体质量指数45(体重:145 kg;高度:178厘米;腰围:135厘米),10年来有糖尿病、高血压和慢性阻塞性肺疾病病史,行左侧经皮肾镜取石术。硬膜外麻醉及俯卧位下手术成功。
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引用次数: 1
Hemoglobin and oxygen transport 血红蛋白和氧气运输
Pub Date : 2016-01-01 DOI: 10.4103/2394-6954.190767
Nagan Varadaraj Nagalakshmi, Ravi Madhusudhana, Nikhila Rajendra, A. Manjunath
Once oxygen (O 2 ) that is present in atmosphere enters the respiratory tract, it reaches the alveoli and diffuses from the alveoli into the pulmonary blood. It is transported to the peripheral tissue capillaries almost entirely in combination with hemoglobin (Hb). The presence of Hb in red blood cells allows the blood to transport 30-100 times as much O 2 as could be transported in the form of dissolved O 2 in blood. This article is based on the published textbooks and articles that speak on the importance of O 2 and Hb; we have tried to put it into one place so that we can relate and apply the concepts.
一旦大气中的氧气(o2)进入呼吸道,它到达肺泡,并从肺泡扩散到肺血液中。它几乎完全与血红蛋白(Hb)结合运输到外周组织毛细血管。血红细胞中Hb的存在使血液运输的o2量是血液中溶解o2量的30-100倍。这篇文章是基于出版的教科书和文章,讲的o2和Hb的重要性;我们试着把它放在一个地方,这样我们就可以联系和应用这些概念。
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引用次数: 4
期刊
Karnataka Anaesthesia Journal
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