Pub Date : 2021-06-30DOI: 10.24304/kjcp.2021.31.2.145
Ki Ung Shin, Hyunjoo Sohn
{"title":"A Survey on Willingness to Accept Community Pharmacist’s Consultation Service Regarding Well-dying","authors":"Ki Ung Shin, Hyunjoo Sohn","doi":"10.24304/kjcp.2021.31.2.145","DOIUrl":"https://doi.org/10.24304/kjcp.2021.31.2.145","url":null,"abstract":"","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88087886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.24304/kjcp.2021.31.2.136
Hyewon Park, S. Lee, Sook Hee An
{"title":"Clinical Effects of Zinc Supplementation in Patients Hospitalized with COVID-19: A Systematic Review and Meta-analysis","authors":"Hyewon Park, S. Lee, Sook Hee An","doi":"10.24304/kjcp.2021.31.2.136","DOIUrl":"https://doi.org/10.24304/kjcp.2021.31.2.136","url":null,"abstract":"","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78778469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.24304/kjcp.2021.31.2.125
Hyo-Jeong Ryu, Won-Ho Kang, J. Chae, Hwi‐yeol Yun
{"title":"Compatibility Study between Physiologically Based Pharmacokinetic (PBPK) and Compartmental PK Model Using Lumping Method: Application to the Voriconazole Case","authors":"Hyo-Jeong Ryu, Won-Ho Kang, J. Chae, Hwi‐yeol Yun","doi":"10.24304/kjcp.2021.31.2.125","DOIUrl":"https://doi.org/10.24304/kjcp.2021.31.2.125","url":null,"abstract":"","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87739818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.24304/kjcp.2021.31.2.96
So Yeon Kim, Y. Choi, Hyunjoo Sohn
{"title":"Awareness on expiration date of repackaged prescription medications and pulverization of solid pills: A questionnaire study","authors":"So Yeon Kim, Y. Choi, Hyunjoo Sohn","doi":"10.24304/kjcp.2021.31.2.96","DOIUrl":"https://doi.org/10.24304/kjcp.2021.31.2.96","url":null,"abstract":"","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81602495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Perception on Drug Utilization Review System and DUR Modernization Pilot Project: A Qualitative Study Using Focus Group Interviews","authors":"Sungho Bea, Ha-Lim Jeon, D. Yoon, Ahhyung Choi, Hyesung Lee, Ju-Young Shin","doi":"10.24304/kjcp.2021.31.2.104","DOIUrl":"https://doi.org/10.24304/kjcp.2021.31.2.104","url":null,"abstract":"","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90326453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-31DOI: 10.24304/KJCP.2021.31.1.35
Yewon Kim, Susin Park, Eonjeong Kim, N. Je
Background: Migraine is a common neurological disorder that affects the quality of life and causes several health problems. Preventive migraine treatment can reduce migraine frequency, headache severity, and health care costs. This study aimed to estimate the utilization of migraine preventive therapy and associated factors in eligible patients. Methods: We studied 534 patients with migraine who were eligible for migraine preventive therapy using 2017 National Patient Sample (NPS) data from the Health Insurance Review and Assessment Service (HIRA). We estimated the migraine days by calculating the monthly average number of defined daily dose (DDD) of migraine-specific acute drug. Patients with a monthly average number of DDD of 4 or more were considered as subjects for preventive treatment. Chi-square test and multiple logistic regression analysis were used to determine the association between the preventive therapy and the influencing variables. Results: Less than half of the eligible patients for prophylaxis (n=234, 43.8%) were prescribed preventive therapy. Multiple logistic regression results show that migraine preventive therapy was influenced by age, the type of migraine, and some comorbidities. Patients over the age of 50 tend to receive less prophylactic treatment than under the age of 40. On the other hand, migraine patients with epilepsy or depression were more likely to receive preventive therapy. Sumatriptan was the most preferred medication for acute treatment, and propranolol was the most commonly prescribed drug for prevention. Conclusions: More than half of the patients who were candidates for migraine prophylaxis were not receiving suitable preventive treatment. Positive factors affecting the use of migraine prevention were the presence of comorbidities such as epilepsy and depression.
{"title":"Utilization of Preventive Therapy in Korean Migraine Patients","authors":"Yewon Kim, Susin Park, Eonjeong Kim, N. Je","doi":"10.24304/KJCP.2021.31.1.35","DOIUrl":"https://doi.org/10.24304/KJCP.2021.31.1.35","url":null,"abstract":"Background: Migraine is a common neurological disorder that affects the quality of life and causes several health problems. Preventive migraine treatment can reduce migraine frequency, headache severity, and health care costs. This study aimed to estimate the utilization of migraine preventive therapy and associated factors in eligible patients. Methods: We studied 534 patients with migraine who were eligible for migraine preventive therapy using 2017 National Patient Sample (NPS) data from the Health Insurance Review and Assessment Service (HIRA). We estimated the migraine days by calculating the monthly average number of defined daily dose (DDD) of migraine-specific acute drug. Patients with a monthly average number of DDD of 4 or more were considered as subjects for preventive treatment. Chi-square test and multiple logistic regression analysis were used to determine the association between the preventive therapy and the influencing variables. Results: Less than half of the eligible patients for prophylaxis (n=234, 43.8%) were prescribed preventive therapy. Multiple logistic regression results show that migraine preventive therapy was influenced by age, the type of migraine, and some comorbidities. Patients over the age of 50 tend to receive less prophylactic treatment than under the age of 40. On the other hand, migraine patients with epilepsy or depression were more likely to receive preventive therapy. Sumatriptan was the most preferred medication for acute treatment, and propranolol was the most commonly prescribed drug for prevention. Conclusions: More than half of the patients who were candidates for migraine prophylaxis were not receiving suitable preventive treatment. Positive factors affecting the use of migraine prevention were the presence of comorbidities such as epilepsy and depression.","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91319728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.24304/kjcp.2020.30.4.270
H. Yoon, Young-ah Cho, Jeong Yee, H. Gwak, Ji Min Han
Clinical and Laboratory Features of Pediatric Patients with COVID-19: Systematic Review and Meta-analysis Ha Young Yoon, Young Ah Cho, Jeong Yee, Hye Sun Gwak*, and Ji Min Han* College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea College of Pharmacy, Gyeongsang National University, Gyeongnam 52828, Republic of Korea Mokhwa Convalescent Hospital, Gyeongnam 52828, Republic of Korea College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea (Received October 4, 2020 · Revised December 14, 2020 · Accepted December 15, 2020)
小儿COVID-19的临床和实验室特征:Ha Young Yoon, Young Ah Cho, Jeong Yee, Hye Sun gak *， Ji Min Han*梨花女子大学药学院和药学研究生院，首尔03760，庆尚大学药学院，庆南52828，韩国木和疗养医院，庆南52828，忠北大学药学院，清州28160(10月4日收)2020·2020年12月14日修订·2020年12月15日接受)
{"title":"Clinical and Laboratory Features of Pediatric Patients with COVID-19: Systematic Review and Meta-analysis","authors":"H. Yoon, Young-ah Cho, Jeong Yee, H. Gwak, Ji Min Han","doi":"10.24304/kjcp.2020.30.4.270","DOIUrl":"https://doi.org/10.24304/kjcp.2020.30.4.270","url":null,"abstract":"Clinical and Laboratory Features of Pediatric Patients with COVID-19: Systematic Review and Meta-analysis Ha Young Yoon, Young Ah Cho, Jeong Yee, Hye Sun Gwak*, and Ji Min Han* College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea College of Pharmacy, Gyeongsang National University, Gyeongnam 52828, Republic of Korea Mokhwa Convalescent Hospital, Gyeongnam 52828, Republic of Korea College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea (Received October 4, 2020 · Revised December 14, 2020 · Accepted December 15, 2020)","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85275153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.24304/kjcp.2020.30.4.264
D. Yun, Ji-Eun Chang, K. Rhew
Background: Inflammatory diseases can increase the prevalence of anemia. Recent studies confirmed that the prevalence of anemia is increased by atopic dermatitis (AD), a chronic inflammatory disease. Therefore, we aimed to elucidate the correlation between AD severity and prevalence of anemia. Methods: We used data of pediatric patients from the Health Insurance Review and Assessment Service (HIRA-PPS-2016). We included pediatric patients ( < 18 years) with AD diagnosis who were prescribed medications for AD. We applied a propensity score method with inverse probability of treatment weighting (IPTW) adjusting for differences in prevalence of confounders and performed IPTW logistic regression to evaluate associations between the anemia and severity of AD. Results: In total, 91,501 patients (mild AD: 47,054 patients; moderate-to-severe AD: 44,447 patients) < 18 years who were prescribed drugs for AD were analyzed. Analysis of the probability of patients with mild AD and prevalence of anemia as a reference revealed an odds ratio (OR) of 1.159 (95% CI, 1.109-1.212; p < 0.001) in moderate-to-severe AD patients, indicating a correlation between anemia prevalence and AD severity. Subgroup analysis according to gender, age group, and type of health insurance revealed there was an association between AD severity and anemia except in patients equal or older than 7 years. Conclusion: The prevalence of anemia increased with AD severity despite adjusting for confounding factors. Our results support the hypothesis that AD can cause anemia, and anemia prevalence could be increased in severe AD patients. Further studies are needed to establish a pathological basis.
{"title":"Analysis of Prevalence of Anemia according to Severity of Atopic Dermatitis","authors":"D. Yun, Ji-Eun Chang, K. Rhew","doi":"10.24304/kjcp.2020.30.4.264","DOIUrl":"https://doi.org/10.24304/kjcp.2020.30.4.264","url":null,"abstract":"Background: Inflammatory diseases can increase the prevalence of anemia. Recent studies confirmed that the prevalence of anemia is increased by atopic dermatitis (AD), a chronic inflammatory disease. Therefore, we aimed to elucidate the correlation between AD severity and prevalence of anemia. Methods: We used data of pediatric patients from the Health Insurance Review and Assessment Service (HIRA-PPS-2016). We included pediatric patients ( < 18 years) with AD diagnosis who were prescribed medications for AD. We applied a propensity score method with inverse probability of treatment weighting (IPTW) adjusting for differences in prevalence of confounders and performed IPTW logistic regression to evaluate associations between the anemia and severity of AD. Results: In total, 91,501 patients (mild AD: 47,054 patients; moderate-to-severe AD: 44,447 patients) < 18 years who were prescribed drugs for AD were analyzed. Analysis of the probability of patients with mild AD and prevalence of anemia as a reference revealed an odds ratio (OR) of 1.159 (95% CI, 1.109-1.212; p < 0.001) in moderate-to-severe AD patients, indicating a correlation between anemia prevalence and AD severity. Subgroup analysis according to gender, age group, and type of health insurance revealed there was an association between AD severity and anemia except in patients equal or older than 7 years. Conclusion: The prevalence of anemia increased with AD severity despite adjusting for confounding factors. Our results support the hypothesis that AD can cause anemia, and anemia prevalence could be increased in severe AD patients. Further studies are needed to establish a pathological basis.","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84184092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.24304/kjcp.2020.30.4.259
M. Oh, H. Ahn, Sunmi Choi, H. La
Background: Dual-type calcium channel blockers (CCBs), such as efonidipine and cilnidipine, are renoprotective drugs that reportedly reduce proteinuria by dilating afferent and efferent arterioles of the glomerulus. However, studies comparing the effect of dual-type CCB on proteinuria have not been conducted. Therefore, we aimed to compare the effect of dual-type CCB (efonidipine and cilnidipine) usage patterns in hypertensive patients with chronic kidney disease (CKD). Methods: This single-center, retrospective study included 53 patients with CKD who 1) initiated efonidipine or cilnidipine treatment while on a renin-angiotensin system inhibitor and 2) had received efonidipine or cilnidipine for at least one year. We compared usage patterns between the efonidipine and cilnidipine groups during the one-year period and analyzed the following outcomes: urinary protein-to-creatinine ratio, blood pressure, and serum creatinine. Results: The study included 25 patients in the efonidipine group and 28 patients in the cilnidipine group. In both groups, blood pressure and urinary protein-to-creatinine ratios tended to decrease; however, the change during each interval was not significant. Conclusions: In patients with CKD who were on renin-angiotensin system inhibitor therapy, the addition of a dual-type CCB (i.e., efonidipine or cilnidipine) tended to reduce proteinuria; however, the change during each interval was not significant.
{"title":"Comparison of Usage Patterns and Outcomes by Dual Type Calcium Channel Blockers in Patients with Chronic Kidney Disease","authors":"M. Oh, H. Ahn, Sunmi Choi, H. La","doi":"10.24304/kjcp.2020.30.4.259","DOIUrl":"https://doi.org/10.24304/kjcp.2020.30.4.259","url":null,"abstract":"Background: Dual-type calcium channel blockers (CCBs), such as efonidipine and cilnidipine, are renoprotective drugs that reportedly reduce proteinuria by dilating afferent and efferent arterioles of the glomerulus. However, studies comparing the effect of dual-type CCB on proteinuria have not been conducted. Therefore, we aimed to compare the effect of dual-type CCB (efonidipine and cilnidipine) usage patterns in hypertensive patients with chronic kidney disease (CKD). Methods: This single-center, retrospective study included 53 patients with CKD who 1) initiated efonidipine or cilnidipine treatment while on a renin-angiotensin system inhibitor and 2) had received efonidipine or cilnidipine for at least one year. We compared usage patterns between the efonidipine and cilnidipine groups during the one-year period and analyzed the following outcomes: urinary protein-to-creatinine ratio, blood pressure, and serum creatinine. Results: The study included 25 patients in the efonidipine group and 28 patients in the cilnidipine group. In both groups, blood pressure and urinary protein-to-creatinine ratios tended to decrease; however, the change during each interval was not significant. Conclusions: In patients with CKD who were on renin-angiotensin system inhibitor therapy, the addition of a dual-type CCB (i.e., efonidipine or cilnidipine) tended to reduce proteinuria; however, the change during each interval was not significant.","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78734320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.24304/kjcp.2020.30.4.250
Tae hyun Jeong, Seoung Min Suh, H. Song, Nakyung Jeon
Impulse Control Disorders associated with Pramipexole/Ropinirole Use in Non-Parkinson’s Disease: A Scoping Review Tae hyun Jeong, Seoung Min Suh, Hyun Jin Song, and Nakyung Jeon* Chonnam National University College of Pharmacy, Gwangju 61186, Republic of Korea University of Florida College of Pharmacy Department of Pharmaceutical Outcomes and Policy, Gainesveill, Florida 32610, United States of America (Received October 24, 2020 · Revised December 7, 2020 · Accepted December 10, 2020)
郑泰铉，Seoung Min Suh, hyun Jin Song, and Nakyung Jeon*全南国立大学药学院，光州61186，大韩民国佛罗里达大学药学院药物效果与政策系，Gainesveill, Florida 32610，美国(2020年10月24日收到·2020年12月7日修订·2020年12月10日接受)
{"title":"Impulse Control Disorders associated with Pramipexole/Ropinirole Use in Non-Parkinson’s Disease: A Scoping Review","authors":"Tae hyun Jeong, Seoung Min Suh, H. Song, Nakyung Jeon","doi":"10.24304/kjcp.2020.30.4.250","DOIUrl":"https://doi.org/10.24304/kjcp.2020.30.4.250","url":null,"abstract":"Impulse Control Disorders associated with Pramipexole/Ropinirole Use in Non-Parkinson’s Disease: A Scoping Review Tae hyun Jeong, Seoung Min Suh, Hyun Jin Song, and Nakyung Jeon* Chonnam National University College of Pharmacy, Gwangju 61186, Republic of Korea University of Florida College of Pharmacy Department of Pharmaceutical Outcomes and Policy, Gainesveill, Florida 32610, United States of America (Received October 24, 2020 · Revised December 7, 2020 · Accepted December 10, 2020)","PeriodicalId":17901,"journal":{"name":"Korean Journal of Clinical Pharmacy","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83868698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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