Journal of VitreoRetinal Diseases最新文献_第8页

Eye Pain During Hemodialysis in Severe Proliferative Diabetic Retinopathy With Neovascular Glaucoma 伴有新生血管性青光眼的严重增殖性糖尿病视网膜病变患者血液透析期间的眼部疼痛

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-02-13 DOI: 10.1177/24741264241230147

Tessnim R. Ahmad, Sriranjani Padmanabhan, Jesse J. Jung

Purpose: To report a case of severe eye pain developing during dialysis. Methods: A case report was performed. Results: A 41-year-old man with uncontrolled type 2 diabetes and end-stage nephropathy developed severe left eye pain during hemodialysis. A decline in vision in both eyes was reported over the preceding year, with blindness in the left eye for 6 months. The best-corrected visual acuity was 20/150 right eye (OD) and light perception left eye (OS). The intraocular pressure was 14 mm Hg and 59 mm Hg, respectively. An examination found disc neovascularization with a “volcanic eruption” of vitreous hemorrhage from the optic nerve in the right eye and significant corneal edema and iris neovascularization with no posterior view in the left eye. The patient required urgent cyclophotocoagulation for neovascular glaucoma (NVG) in the left eye, bilateral antivascular endothelial growth factor injections, and panretinal photocoagulation in the right eye for proliferative diabetic retinopathy. Conclusions: Worsening eye pain during hemodialysis in a patient with NVG indicates severely limited outflow capacity and requires immediate intervention.

目的：报告一例在透析过程中出现严重眼痛的病例。方法：进行病例报告：进行病例报告。结果：一名 41 岁的男性患者患有未得到控制的 2 型糖尿病和终末期肾病，在血液透析期间出现左眼剧烈疼痛。据报告，在过去的一年中，他的双眼视力下降，左眼失明长达 6 个月。最佳矫正视力为右眼（OD）20/150，左眼（OS）有光感。眼压分别为 14 毫米汞柱和 59 毫米汞柱。检查发现，右眼视盘有新生血管，视神经玻璃体出血呈 "火山爆发 "状；左眼角膜明显水肿，虹膜有新生血管，后方无视野。患者左眼因新生血管性青光眼（NVG）需要紧急进行环形光凝，双侧需要注射抗血管内皮生长因子，右眼因增殖性糖尿病视网膜病变需要进行全视网膜光凝。结论患有 NVG 的患者在血液透析期间眼痛加剧，表明其眼球流出能力严重受限，需要立即进行干预。

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引用次数: 0

Descriptive Analysis of Vitreoretinal Surgery Fellowship Program Directors 玻璃体视网膜手术研究员项目主任的描述性分析

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-02-12 DOI: 10.1177/24741264241230385

Cheng Jiao, P. Patel, Shadman Ibnamasud, Prem N. Patel, Harris Ahmed, Janice C. Law

Purpose: To evaluate the demographic, educational, and scholarly characteristics of Association of University Professors of Ophthalmology–accredited vitreoretinal surgery fellowship program directors in the United States and Canada. Methods: Demographic, educational, and scholarly profiles of identified program directors were collated from online public resources. Characteristics were compared by sex, program size, ranking, and affiliation. Results: Eighty-one program directors (mean age [±SD] 54.7 ± 11.0 years) from 78 fellowship programs were identified. The minority were women (14.8%), who were on average 6 years younger than their male counterparts ( P = .07). The majority of program directors had an academic affiliation (90.1%), most commonly professor (54.8%). The mean h-index, 5-year h-index, and m-quotient were 20.9 ± 14.9, 5.9 ± 4.4, and 0.82 ± 0.42, respectively. Compared with their counterparts, program directors of both “top 10” and large programs published more manuscripts ( P < .05), accrued more citations ( P < .05), and had a higher h-index ( P < .05). Fellowship programs with female program directors had a significantly larger proportion of female retina faculty ( P = .002). Conclusions: The backgrounds of vitreoretinal surgery program directors are diverse. However, women remain underrepresented in this position, highlighting an area with the potential for greater equity in ophthalmology.

目的：评估美国和加拿大经大学眼科教授协会认证的玻璃体视网膜手术研究金项目主任的人口、教育和学术特征。研究方法：从在线公共资源中整理已确定的项目主任的人口、教育和学术概况。按性别、项目规模、排名和所属单位对其特征进行比较。结果确定了来自 78 个研究金项目的 81 名项目主任（平均年龄 [±SD] 54.7 ± 11.0 岁）。女性占少数（14.8%），平均年龄比男性小 6 岁 ( P = .07)。大多数项目主任具有学术背景（90.1%），其中最常见的是教授（54.8%）。平均 h 指数、5 年 h 指数和 m 商数分别为 20.9 ± 14.9、5.9 ± 4.4 和 0.82 ± 0.42。与同行相比，"前十名 "项目和大型项目的项目主任发表的手稿更多 ( P < .05)，被引用的次数更多 ( P < .05)，h 指数更高 ( P < .05)。由女性担任项目主任的研究项目中，视网膜专业的女性教师比例明显更高 ( P = .002)。结论：玻璃体视网膜手术项目主任的背景多种多样。然而，女性在这一职位上的人数仍然不足，这凸显了眼科领域有可能实现更大的公平。

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引用次数: 0

Descriptive Analysis of Vitreoretinal Surgery Fellowship Program Directors 玻璃体视网膜手术研究员项目主任的描述性分析

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-02-12 DOI: 10.1177/24741264241230385

Cheng Jiao, P. Patel, Shadman Ibnamasud, Prem N. Patel, Harris Ahmed, Janice C. Law

Purpose: To evaluate the demographic, educational, and scholarly characteristics of Association of University Professors of Ophthalmology–accredited vitreoretinal surgery fellowship program directors in the United States and Canada. Methods: Demographic, educational, and scholarly profiles of identified program directors were collated from online public resources. Characteristics were compared by sex, program size, ranking, and affiliation. Results: Eighty-one program directors (mean age [±SD] 54.7 ± 11.0 years) from 78 fellowship programs were identified. The minority were women (14.8%), who were on average 6 years younger than their male counterparts ( P = .07). The majority of program directors had an academic affiliation (90.1%), most commonly professor (54.8%). The mean h-index, 5-year h-index, and m-quotient were 20.9 ± 14.9, 5.9 ± 4.4, and 0.82 ± 0.42, respectively. Compared with their counterparts, program directors of both “top 10” and large programs published more manuscripts ( P < .05), accrued more citations ( P < .05), and had a higher h-index ( P < .05). Fellowship programs with female program directors had a significantly larger proportion of female retina faculty ( P = .002). Conclusions: The backgrounds of vitreoretinal surgery program directors are diverse. However, women remain underrepresented in this position, highlighting an area with the potential for greater equity in ophthalmology.

目的：评估美国和加拿大经大学眼科教授协会认证的玻璃体视网膜手术研究金项目主任的人口、教育和学术特征。研究方法：从在线公共资源中整理已确定的项目主任的人口、教育和学术概况。按性别、项目规模、排名和所属单位对其特征进行比较。结果确定了来自 78 个研究金项目的 81 名项目主任（平均年龄 [±SD] 54.7 ± 11.0 岁）。女性占少数（14.8%），平均年龄比男性小 6 岁 ( P = .07)。大多数项目主任具有学术背景（90.1%），其中最常见的是教授（54.8%）。平均 h 指数、5 年 h 指数和 m 商数分别为 20.9 ± 14.9、5.9 ± 4.4 和 0.82 ± 0.42。与同行相比，"前十名 "项目和大型项目的项目主任发表的手稿更多 ( P < .05)，被引用的次数更多 ( P < .05)，h 指数更高 ( P < .05)。由女性担任项目主任的研究项目中，视网膜专业的女性教师比例明显更高 ( P = .002)。结论：玻璃体视网膜手术项目主任的背景多种多样。然而，女性在这一职位上的人数仍然不足，这凸显了眼科领域有可能实现更大的公平。

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引用次数: 0

Pentosan Polysulfate Maculopathy With 13 Years of Follow-up Imaging 随访 13 年的硫酸戊聚糖黄斑病变图像

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-31 DOI: 10.1177/24741264241228375

Ashlyn M. Pinto, Nieraj Jain, R. R. Gupta

Purpose: To describe a case of pentosan polysulfate maculopathy progression with 13 years of follow-up imaging. Methods: A case was analyzed and a literature review performed. Results: A 65-year-old woman was referred to the retina service for a second opinion of a bilateral progressive pigmentary maculopathy. Her medical history was significant for interstitial cystitis that was actively treated with daily pentosan polysulfate since 2003. Multimodal imaging and fundus examination were consistent with pentosan polysulfate maculopathy. A review of records showed previous fundus imaging dating back 13 years that permitted longitudinal assessment of the disease course. Imaging findings were more prominent than the fundus examination findings. There was a 5-year period from the onset of parafoveal atrophy to foveal involvement. A pseudopodial pattern of disease expansion was seen on fundus autofluorescence. Conclusions: To our knowledge, this case represents the longest documented follow-up imaging of the progression of pentosan polysulfate maculopathy in the literature.

目的：描述一例随访 13 年的多硫酸戊聚糖黄斑病变病例。方法：对一个病例进行分析，并对文献进行回顾：分析一例病例并进行文献综述。结果：一名 65 岁的妇女因双侧进行性色素性黄斑病变被转诊至视网膜科，寻求第二意见。她的病史主要是间质性膀胱炎，自2003年起每天使用多硫酸戊聚糖积极治疗。多模态成像和眼底检查结果与多硫酸戊聚糖黄斑病变一致。病历回顾显示，眼底成像可追溯到 13 年前，可对病程进行纵向评估。成像结果比眼底检查结果更为突出。从开始出现眼底萎缩到眼窝受累，共经历了5年时间。眼底自发荧光显示疾病呈假性点状扩展。结论：据我们所知，该病例是文献中对多硫酸戊聚糖黄斑病变进展过程进行随访成像记录时间最长的病例。

引用次数: 0

Occlusive Retinal Vasculitis After a Single Injection of Pegcetacoplan. 单次注射 Pegcetacoplan 后的闭塞性视网膜血管炎

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-30 eCollection Date: 2024-03-01 DOI: 10.1177/24741264241228648

Mariana Abi Karam, Janet L Davis, Stephen G Schwartz

Purpose: To describe a patient with retinal vasculitis after a single intravitreal injection (IVI) of pegcetacoplan. Methods: A case and its findings were analyzed. Results: An 80-year-old woman was treated with pegcetacoplan for subfoveal geographic atrophy. Ten days later, the patient noted "purple iridescent waves" but did not immediately report it. On day 18, she presented with pain and decreased visual acuity from 20/80 (pinhole) preinjection to 20/150 postinjection. No signs of inflammation were observed, and she was treated for high intraocular pressure (30 mm Hg). On day 23, iritis was noted. The fluorescein angiogram showed severe occlusive vasculitis involving all quadrants and the macula. The vasculitis/neuroretinitis laboratory panels were negative, and no contributing systemic features were identified other than well-controlled diabetes. Conclusions: In this patient, occlusive retinal vasculitis occurred shortly after a single IVI of pegcetacoplan.

目的：描述一名视网膜血管炎患者在单次静脉注射（IVI）培西他克普兰后的情况。方法：分析一个病例及其研究结果。结果：一名 80 岁的妇女因眼底地理萎缩接受了培加氯普兰治疗。10 天后，患者发现 "紫色彩虹波"，但没有立即报告。第 18 天，她出现疼痛，视力从注射前的 20/80（针孔）下降到注射后的 20/150。没有观察到炎症迹象，她因眼压过高（30 毫米汞柱）接受了治疗。第 23 天，她出现了虹膜炎。荧光素血管造影显示，严重的闭塞性血管炎累及所有象限和黄斑。血管炎/神经视网膜炎实验室检查结果为阴性，除糖尿病控制良好外，未发现其他全身特征。结论：该患者在接受一次培加氯普兰静脉注射后不久就发生了闭塞性视网膜血管炎。

引用次数: 0

Ophthalmologic Presentations of Incontinentia Pigmenti. 皮格蒙特失禁症的眼科表现。

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-28 eCollection Date: 2024-03-01 DOI: 10.1177/24741264241227680

Ravneet S Rai, Albert S Li, Philip J Ferrone

Purpose: To characterize treatments and outcomes in incontinentia pigmenti. Methods: Cases of incontinentia pigmenti were consecutively identified from a retina practice. Inclusion criteria were patients with incontinentia pigmenti with at least 6 months of follow-up. All patients had a full ophthalmic examination, including imaging with widefield fundus photography and widefield fluorescein angiography. Eyes with areas of avascular retina were treated with laser photocoagulation (except for 1 eye with mild changes). Results: Thirty-six eyes of 18 patients with incontinentia pigmenti were included. The median age at presentation was 11 months. On presentation, 7 eyes had a visual acuity (VA) of 20/40 or better and 3 eyes had VA of 20/50 to 20/100. The remaining 26 eyes could fix and follow or had at least light perception (LP) VA given the patients' young age. Of the 36 eyes, 20 (56%) had retinal involvement. The mean follow-up for treated patients was 6.9 years. Seventy-four percent of treated eyes required 1 laser session only. No eye that received laser treatment subsequently developed a retinal detachment. Of the 26 eyes with initial fix-and-follow or LP VA, 12 had Snellen or Allen VA testing at follow-up. Nine of these eyes had a follow-up VA of 20/40 or better. Of 10 eyes with a Snellen or Allen VA recorded at the initial visit, 9 had a final VA that was the same or improved. Conclusions: Laser photocoagulation was effective in treating patients with retinal manifestations of incontinentia pigmenti. Except for 1 eye, VA remained stable at the final follow-up.

目的：了解猪尿失禁症的治疗方法和效果。方法从一家视网膜诊所连续确定猪尿失禁病例。纳入标准为至少随访 6 个月的猪尿失禁患者。所有患者均接受了全面的眼科检查，包括宽视野眼底照相术和宽视野荧光素血管造影术。对出现视网膜血管缺损的眼睛进行了激光光凝治疗（只有一只眼睛有轻微变化除外）。结果共纳入了 18 名猪尿失禁患者的 36 只眼睛。发病时的中位年龄为 11 个月。发病时，7 只眼睛的视力为 20/40 或更佳，3 只眼睛的视力为 20/50 至 20/100。鉴于患者年龄较小，其余 26 只眼睛可以固定和跟踪或至少有光感（LP）视力。在 36 只眼睛中，20 只（56%）视网膜受累。接受治疗的患者的平均随访时间为 6.9 年。74%的患者只需接受一次激光治疗。接受激光治疗的患者中没有一只眼随后发生视网膜脱离。在 26 只最初有固定视力或低视力的眼睛中，有 12 只在随访时接受了斯奈伦或艾伦视力测试。其中 9 只眼睛的随访视力达到或超过 20/40。在初诊时记录有斯奈伦或艾伦视力的 10 只眼睛中，9 只眼睛的最终视力与初诊时相同或有所提高。结论：激光光凝治疗猪尿失禁视网膜表现患者效果显著。除一只眼外，其他患者的视力在最终随访时保持稳定。

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引用次数: 0

Long-Term Stability of Melanocytomas With Persistent Vascular Activity Without Malignant Transformation 具有持续血管活性但未发生恶性转化的黑色素细胞瘤的长期稳定性

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-22 DOI: 10.1177/24741264241227692

Sophia Bonafonte, Aaron S. Gold, Azeema Latiff, Timothy G. Murray

Purpose: To present 2 cases of large atypical melanocytomas that simulate melanoma. Methods: The largest risk factors for malignant transformation from melanocytoma into malignant melanoma are a combination of lesions with a thickness greater than 2 mm, visual symptoms, and tumor margin at the disc. The patients in this report were chosen because they both presented these factors with their lesions. Results: Because the lesions were properly identified as melanocytomas of the optic disc, the decision was made to monitor them closely and treat the associated vascular activity. Ultrasounds and close observations are key in differentiating these benign lesions from malignant melanomas. Conclusion: Both patients experienced long-term stability with intravitreal injections when needed for vascular activity.

目的：介绍 2 例模拟黑色素瘤的巨大非典型黑色素细胞瘤。方法：从黑色素细胞瘤恶变为恶性黑色素瘤的最大风险因素是病变厚度大于 2 毫米、视觉症状和椎间盘处肿瘤边缘。之所以选择本报告中的患者，是因为他们的病变都存在这些因素。结果：由于病变被正确识别为视盘黑色素细胞瘤，因此决定对其进行密切监测，并治疗相关的血管活动。超声波检查和密切观察是区分这些良性病变和恶性黑色素瘤的关键。结论这两名患者都在需要治疗血管活动时接受了玻璃体内注射，病情长期稳定。

引用次数: 0

Mean Ocular Perfusion Pressure Effect During Pars Plana Vitrectomy on the Foveal Avascular Zone: A Pilot Study 玻璃体旁切除术期间平均眼灌注压对眼窝血管区的影响：试点研究

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-19 DOI: 10.1177/24741264231223389

F. Shaheen, Hashim Ali Khan, Farooq Afzal, Muhammad Amer Awan

Purpose: To evaluate the effect of mean ocular perfusion pressure on the foveal avascular zone (FAZ) area in eyes with successful retinal detachment (RD) surgery. Methods: This prospective pilot fellow eye–controlled study measured the intraoperative mean ocular perfusion pressure in eyes having surgery for rhegmatogenous RD (RRD). Postoperatively, the FAZ area was measured; the change was calculated as the difference in the FAZ area between the operated eye and the contralateral control eye. Results: The study comprised 8 patients with a mean age (±SD) of 53.38 ± 13.92 years. The mean superficial FAZ area was not different between operated eyes and control eyes, while the deep FAZ area was significantly larger in operated eyes. There was a strong negative correlation between the mean ocular perfusion pressure and the change in the deep FAZ area (Spearman ρ, −0.73; P = .04); the correlation between the mean ocular perfusion pressure and the change in the superficial FAZ area was not significant (Spearman ρ, −0.24; P = .57). A significant linear regression was found between the mean ocular perfusion pressure and the change in the deep FAZ area (R2 = 0.388). The predicted enlargement of the deep FAZ area was 0.03 mm with every 1 mm Hg decrease in the mean ocular perfusion pressure. Conclusion: Lower intraoperative mean ocular perfusion pressure is associated with enlargement of the deep FAZ area in eyes having successful RRD surgery.

目的：评估平均眼球灌注压对视网膜脱离（RD）手术成功眼的眼窝无血管区（FAZ）面积的影响。方法：采用前瞻性试验性同工眼对照方法：这项前瞻性试验性同胞眼对照研究测量了流变性视网膜脱离（RRD）手术眼的术中平均眼球灌注压。术后测量FAZ面积，并以手术眼与对侧对照眼FAZ面积之差计算其变化。研究结果本研究共有 8 名患者，平均年龄（±SD）为 53.38±13.92 岁。手术眼和对照眼的平均浅层 FAZ 面积没有差异，而手术眼的深层 FAZ 面积明显更大。平均眼球灌注压与FAZ深层面积的变化之间存在很强的负相关（Spearman ρ，-0.73；P = .04）；平均眼球灌注压与FAZ浅层面积的变化之间的相关性不显著（Spearman ρ，-0.24；P = .57）。平均眼球灌注压与深层 FAZ 面积变化之间存在明显的线性回归关系（R2 = 0.388）。平均眼球灌注压每降低 1 mm Hg，深 FAZ 面积的预测增大值为 0.03 mm。结论：在成功进行 RRD 手术的眼球中，术中平均眼球灌注压降低与 FAZ 深部面积扩大有关。

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引用次数: 0

Outcomes of Chandelier-Assisted Scleral Buckling in Rhegmatogenous Retinal Detachments: Systematic Review and Meta-analysis Chandelier 辅助巩膜扣带术治疗风湿性视网膜脱离的疗效：系统回顾和元分析

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-19 DOI: 10.1177/24741264231224956

Daniel Zhu, Amanda Wong, George Jiao, Charles Zhang, Daniela Yakobashvili, Edward Zhu, Tristan Tham, Ronni Lieberman

Purpose: To examine the outcomes of chandelier endoillumination–assisted scleral buckling (chandelier scleral buckling) for rhegmatogenous retinal detachments (RRDs) and compare them with those of standard scleral buckling using indirect ophthalmoscopy. Methods: A literature search was performed on April 15, 2023. Outcomes analyzed included primary anatomic success rates, surgical duration, and complication rates. A meta-analysis of proportions estimated the pooled success rate of chandelier scleral buckling. In addition, meta-analyses compared the success rates between pseudophakic eyes and phakic eyes having chandelier scleral buckling and compared success rates and surgical duration between standard scleral buckling and chandelier scleral buckling. Results: Thirty studies with 1133 eyes were included. The pooled primary anatomic success rate of chandelier scleral buckling was 91.7% (95% CI, 89.6%-93.6%). In studies comparing success rates between the 2 techniques, there was no significant difference (risk ratio, 1.01; 95% CI, 0.94-1.08; P = .80). The surgical times were significantly shorter with chandelier scleral buckling than with standard scleral buckling (mean difference, −18.83; 95% CI, −30.88 to −6.79; P = .002). There was no significant difference in the success rate between pseudophakic eyes and phakic eyes (risk ratio, 0.99; 95% CI, 0.91-1.08; P = .89). No cases of endophthalmitis were reported. Conclusions: Chandelier endoillumination–assisted scleral buckling may be a promising technique given its high rate of primary anatomic success for RRDs and success rates similar to those of standard scleral buckling. There was no significant difference in the efficacy of chandelier scleral buckling between pseudophakic eyes and phakic eyes

目的：研究吊灯内照射辅助巩膜扣带术（吊灯巩膜扣带术）治疗流变性视网膜脱离（RRD）的效果，并与使用间接眼底镜的标准巩膜扣带术的效果进行比较。方法：于 2023 年 4 月 15 日进行文献检索。分析的结果包括主要解剖成功率、手术持续时间和并发症发生率。比例荟萃分析估计了吊灯式巩膜扣锁术的总成功率。此外，荟萃分析还比较了假性视网膜眼和接受吊灯式巩膜扣锁术的视网膜眼的成功率，并比较了标准巩膜扣锁术和吊灯式巩膜扣锁术的成功率和手术持续时间。结果：共纳入 30 项研究，1133 只眼睛。吊灯式巩膜扣锁术的主要解剖成功率为 91.7%（95% CI，89.6%-93.6%）。在比较两种技术的成功率的研究中，两者没有显著差异（风险比，1.01；95% CI，0.94-1.08；P = .80）。吊灯式巩膜扣锁术的手术时间明显短于标准巩膜扣锁术（平均差异为-18.83；95% CI为-30.88至-6.79；P = .002）。假性视网膜眼和法眼的成功率没有明显差异（风险比，0.99；95% CI，0.91-1.08；P = .89）。无眼底炎病例报告。结论吊灯内照射辅助巩膜扣带术可能是一种很有前途的技术，因为它对RRD的初级解剖成功率很高，而且成功率与标准巩膜扣带术相似。假性眼和隐形眼的吊灯巩膜扣合疗效无明显差异

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引用次数: 0

Outcomes of Eyes Lost to Follow-up After Treatment With Intraocular or Periocular Steroid Injections 眼内或眼周类固醇注射治疗后失去随访眼的结果

IF 0.6

Journal of VitreoRetinal Diseases

Pub Date : 2024-01-19 DOI: 10.1177/24741264231218044

R. Mahmoudzadeh, Mirataollah Salabati, Rachel N. Israilevich, John W. Hinkle, Anthony Obeid, M. Ali Khan, Jason Hsu, V. Chaudhary, Sunir J. Garg

Purpose: To evaluate the visual, intraocular pressure (IOP), and anatomic outcomes of eyes with loss to follow-up (LTFU) after intravitreal or periocular steroid injections. Methods: Patients receiving intraocular or periocular steroid injections and LTFU for at least 180 days were included in this retrospective cohort study. Charts were reviewed for the visual acuity (VA), IOP, and central foveal thickness at the visit before LTFU, the first return visit, and 3, 6, and 12 months after return. Results: Fifty-three eyes of 47 patients were identified. The mean (±SD) age was 62.3 ± 14.9 years, the mean LTFU time was 295 ± 181.2 days (range, 182-1101), and the mean follow-up after return was 354 ± 339.3 days (range, 32-1141). The overall mean number of steroid injections was 5.2 ± 3.9 (range, 1-18). Compared with the mean logMAR VA at the visit before LTFU (0.59 [Snellen 20/77]), the mean VA remained stable at all timepoints after return as follows: return visit, 0.62 [20/83]; P = .6), month 3 (0.55 [20/70]; P = .6), month 6 (0.55 [20/70]; P = .5), month 12 (0.64 [20/87]; P = .6), and final visit (0.69 [20/97]; P = .2). At the first return visit, 8 (15%) of 53 patients had an IOP of 21 mm Hg or higher (range, 21-31); 2 required treatment with a new antihypertensive medication (latanoprost and timolol, respectively). Conclusion: Patients with LTFU after receiving steroid injections maintained their VA. No patient required incisional glaucoma surgery. Compared with other etiologies, eyes with diabetic macular edema had a greater increase in IOP.

目的：评估玻璃体内或眼周注射类固醇后失去随访（LTFU）的眼睛的视力、眼压（IOP）和解剖结果。方法：这项回顾性队列研究纳入了接受眼内或眼周类固醇注射且失访至少 180 天的患者。研究人员查看了患者在停药前、首次复诊、复诊后 3 个月、6 个月和 12 个月的视力 (VA)、眼压和中心眼窝厚度的病历。结果：确定了 47 名患者的 53 只眼睛。平均年龄（±SD）为 62.3 ± 14.9 岁，LTFU 平均时间为 295 ± 181.2 天（范围为 182-1101），复诊后平均随访时间为 354 ± 339.3 天（范围为 32-1141）。类固醇注射的总平均次数为 5.2 ± 3.9（范围为 1-18）次。与LTFU前就诊时的平均logMAR VA值（0.59 [Snellen 20/77]）相比，复诊后所有时间点的平均VA值均保持稳定，具体如下：复诊时，0.62[20/83]；P = .6）、第 3 个月（0.55 [20/70]；P = .6）、第 6 个月（0.55 [20/70]；P = .5）、第 12 个月（0.64 [20/87]；P = .6）和最后一次回访（0.69 [20/97]；P = .2）。在首次回访时，53 名患者中有 8 人（15%）的眼压达到或超过 21 毫米汞柱（范围为 21-31）；2 人需要使用新的降压药物（分别是拉坦前列素和噻吗洛尔）。结论接受类固醇注射后，LTFU 患者的视力保持不变。没有患者需要进行青光眼切开手术。与其他病因相比，糖尿病性黄斑水肿患者的眼压上升幅度更大。

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引用次数: 0