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[Acute scrotum in children]. [儿童急性阴囊炎]。
Pub Date : 2024-09-03
Anna-Maria Zadig, Gylfi Ásbjörnsson, Martin Salö

Acute scrotum in a child is common, and the main underlying conditions are torsion of intrascrotal appendages, epididymitis, testicular torsion and idiopathic scrotal edema. The main diagnostic aim is to confirm or rule out testicular torsion, since this may lead to irreversible ischemia within hours. The diagnostics can be difficult, especially in prepubertal boys, but consist of a thorough history and clinical examination, the use of a clinical prediction score, and sometimes ultrasound with doppler. However, none of these tools can with completely accuracy rule out a testicular torsion, and uncertainty should prompt an acute scrotal exploration. The treatment of a testicular torsion is detorsion and bilateral orchidopexy, or unilateral orchidectomy in case of a completely necrotic testicle. Treatment of the other underlying conditions is often only symptomatic, and follow-up is often not required.

儿童急性阴囊炎很常见,其主要病因是阴囊内附属物扭转、附睾炎、睾丸扭转和特发性阴囊水肿。诊断的主要目的是确认或排除睾丸扭转,因为这可能会在数小时内导致不可逆的缺血。诊断可能很困难,尤其是对青春期前的男孩,但诊断包括全面的病史和临床检查、临床预测评分,有时还包括多普勒超声检查。然而,这些工具都不能完全准确地排除睾丸扭转的可能性,如果不能确定,应进行急性阴囊探查。睾丸扭转的治疗方法是扭转和双侧睾丸切除术,如果睾丸完全坏死,则进行单侧睾丸切除术。对其他潜在疾病的治疗通常只是对症处理,通常不需要随访。
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引用次数: 0
[Spontaneous coronary artery dissection and physical activity - what we know and don't know]. [自发性冠状动脉夹层与体育锻炼--我们知道的和不知道的]。
Pub Date : 2024-09-02
Nina Johnston, Sofia Sederholm Lawesson, Eva Swahn

Patients suffering from a spontaneous coronary artery dissection (SCAD) are mostly younger to middle-aged women. There are very few data to guide physicians and physiotherapists on recommendations about physical activity for these patients. Based on the few studies that are available, aerobic activity at moderate levels and weightlifting with light weights appears safe. No studies are available on SCAD patients and aerobic activity, at more intensive levels. Follow-up studies after SCAD suggest that many patients receive advice with restrictions on physical activity resulting in a sedentary lifestyle.

自发性冠状动脉夹层(SCAD)患者多为中青年女性。很少有数据可以指导医生和物理治疗师为这些患者推荐体育锻炼。根据现有的少量研究,中等强度的有氧运动和轻重量的举重运动似乎是安全的。目前还没有关于 SCAD 患者和高强度有氧运动的研究。SCAD 术后的随访研究表明,许多患者在接受建议时会受到体育锻炼的限制,从而导致久坐不动的生活方式。
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引用次数: 0
[Managing medicine shortages: responsibilities and strategies at the Swedish Medical Products Agency]. [管理药品短缺:瑞典医药产品局的责任和战略]。
Pub Date : 2024-08-27
Sophia Persson Käll, Veronica Arthurson, Maria Wanrud, Luisa Becedas, Rickard Ljung

The paper outlines the role of the Swedish Medical Products Agency (Läkemedelsverket) in managing medicine shortages. The agency receives reports from pharmaceutical companies, investigates causes, and disseminates information to pharmacies, healthcare providers, and the public. While focusing on mitigating shortages, the agency clarifies its non-involvement in manufacturing or sales decisions. Pharmaceutical companies must promptly report shortages, with sanctions enforced for non-compliance. Various measures, including regulatory actions, interchangeable medicines, temporary dispensations, and licensing, are employed to address shortages. Additionally, the agency advocates for stable national drug supply preparedness, emphasizing collaboration and governmental intervention.

本文概述了瑞典医药产品管理局(Läkemedelsverket)在管理药品短缺方面的作用。该机构接收制药公司的报告,调查原因,并向药店、医疗服务提供者和公众发布信息。在关注缓解药品短缺的同时,该机构明确表示不参与生产或销售决策。制药公司必须及时报告短缺情况,并对违规行为实施制裁。为解决药品短缺问题,该机构采取了各种措施,包括监管行动、互换药品、临时配药和发放许可证。此外,该机构还倡导稳定的国家药品供应准备,强调合作和政府干预。
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引用次数: 0
[Increased self-reported eating disorder symptoms in outpatients at a Child and Adolescent Psychiatry Clinic in Sweden between 2018 and 2022]. [2018年至2022年期间,瑞典一家儿童和青少年精神病诊所门诊患者自我报告的饮食失调症状有所增加]。
Pub Date : 2024-08-22
Helena Zetterqvist, Tove Marthin, Kent W Nilsson, Maria Hedqvist, Susanne Olofsdotter

Eating disorders are common disorders that cause significant suffering and functional impairment for those affected. They often emerge in adolescence and can go undetected for many years before an individual presents to services. Early diagnosis and treatment have been shown to significantly improve the prognosis, highlighting the need for proactive screening. This study compared the frequency of self-reported eating disorder symptoms in (n = 2137) outpatients at the Child and Adolescent Psychiatry Clinic (BUP) in Region Västmanland, Sweden between 2018 and 2022. The results showed that the proportion of young people reporting frequent eating disorder symptoms increased from 16% to 28% over this time period. This result is in line with previous research describing an increase in the prevalence of eating disorder symptoms among different groups in relation to the Covid-19 pandemic. It underscores the importance of screening for eating disorder symptoms to better address care needs.

进食障碍是一种常见的疾病,会给患者带来极大的痛苦和功能障碍。饮食失调症通常在青春期出现,患者可能多年未被发现,直到接受治疗。事实证明,早期诊断和治疗可明显改善预后,这也凸显了主动筛查的必要性。这项研究比较了2018年至2022年期间瑞典韦斯特曼兰地区儿童和青少年精神病诊所(BUP)门诊患者(n = 2137)自我报告的饮食失调症状频率。结果显示,在此期间,报告经常出现饮食失调症状的青少年比例从 16% 上升至 28%。这一结果与之前的研究结果一致,即不同群体中饮食失调症状的流行率增加与 Covid-19 大流行有关。这强调了筛查饮食失调症状以更好地满足护理需求的重要性。
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引用次数: 0
[New Swedish national guidelines - management of Percuteaneous Endoscopic Gastrostomy (PEG) and other enteral feeding tubes]. [瑞典国家新指南--经皮内镜胃管造口术(PEG)和其他肠内喂养管的管理]。
Pub Date : 2024-08-21
Karin Stenberg, Anna Eriksson, Ulrika Tullberg, Peter T Schmidt, Peter Elbe

Numerous patients stand to gain significant health benefits from enteral nutrition support facilitated by percutaneous feeding tubes. Consequently it is crucial for endoscopists, general practitioners, surgeons and neurologists to be well-versed with indications, contraindications and potential complications of PEG and other enteral feeding tubes. In this context we present a concise overview of the new national guidelines by the Swedish Society of Gastroenterology regarding the management of PEG and other enteral feeding tubes. Indications for the use of enteral feeding tubes include conditions such as stroke and obstructive cancer. The care of patients with percutaneous feeding tubes necessitates the expertise of a specialized team. Complications related to PEG include, among others, buried bumper syndrome, local infection and dislocation of the feeding tube.

经皮输液管提供的肠内营养支持将为众多患者带来巨大的健康益处。因此,内窥镜医生、全科医生、外科医生和神经科医生必须熟知 PEG 和其他肠内喂养管的适应症、禁忌症和潜在并发症。在这种情况下,我们将简要介绍瑞典胃肠病学会关于 PEG 和其他肠内喂养管管理的新国家指导方针。使用肠饲管的适应症包括中风和阻塞性癌症等疾病。对使用经皮进食管的患者进行护理需要专业团队的专业知识。与经皮食管插管相关的并发症包括埋置碰击综合症、局部感染和食管脱位等。
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引用次数: 0
Ovanligt symtom med hög klinisk valör vid Hodgkins lymfom. 霍奇金淋巴瘤中具有较高临床价值的异常症状。
Pub Date : 2024-08-20
Elsa Lanke, Thomas Relander
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引用次数: 0
Proteinreducerad kost behöver återupptäckas vid njursvikt. 肾衰竭患者需要重新发现减少蛋白质的饮食。
Pub Date : 2024-08-19
Sintra Eyre, Per Ola Attman, Gerd Faxén Irving, Bengt Lindholm
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引用次数: 0
[Hodgkin lymphoma - pain at alcohol consumption as the only symptom]. [霍奇金淋巴瘤--饮酒时疼痛是唯一症状]。
Pub Date : 2024-08-19
Daniel Molin

The authors Lanke and Relander describe a patient with classical Hodgkin lymphoma (cHL) stage IIA, who had pain at alcohol consumption as the only symptom at diagnosis. The patient was treated with 4 cycles of ABVD chemotherapy and proton therapy 29.75 Gy (RBE). Apart from FDG-PET/CT the course of the disease was followed with serum-TARC. The case illustrates the value of knowing also rare symptoms at the general practice, the usefulness of TARC as a tumour marker in cHL, and the use of proton therapy in order to further reduce late radiotherapy side effects.

作者Lanke和Relander描述了一名典型霍奇金淋巴瘤(cHL)IIA期患者,确诊时唯一的症状就是饮酒时疼痛。患者接受了 4 个周期的 ABVD 化疗和 29.75 Gy (RBE) 质子治疗。除 FDG-PET/CT 外,还通过血清-TARC 追踪了病程。该病例说明了在全科诊疗中了解罕见症状的价值、TARC 作为 cHL 肿瘤标志物的实用性,以及使用质子疗法以进一步减少后期放疗副作用的重要性。
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引用次数: 0
[Health-related quality of life for patients with inflammatory bowel disease requires more than anti-inflammatory treatment]. [炎症性肠病患者与健康相关的生活质量需要的不仅仅是抗炎治疗]。
Pub Date : 2024-08-07
Stefan Lindgren, Sven Almer, Daniel Bergemalm, Olof Grip, Per M Hellström, Henrik Hjortswang, Hans Strid

The care of IBD patients aims to achieve the best possible health. The treatment goals in IBD should therefore, in addition to stable control of intestinal inflammation, also consider health-related quality of life (HRQL) and extraintestinal complications. Fatigue is an underrecognized array of symptoms that need more attention and, if possible, treatment. Iron deficiency is very common in IBD patients and should be monitored at regular intervals and treated. Deficiencies in vitamin D, calcium and phosphate are probably common and can be related to both the disease and the treatments, with a risk of reduced HRQL.

对 IBD 患者的治疗旨在实现尽可能好的健康。因此,IBD 的治疗目标除了稳定控制肠道炎症外,还应考虑与健康相关的生活质量(HRQL)和肠道外并发症。疲劳是一系列未得到充分认识的症状,需要更多关注,并在可能的情况下进行治疗。缺铁在 IBD 患者中非常常见,应定期监测并治疗。维生素 D、钙和磷酸盐的缺乏也很常见,可能与疾病和治疗方法有关,并有降低 HRQL 的风险。
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引用次数: 0
[Human papillomavirus type 18 - In memoriam]. [人类乳头瘤病毒 18 型--悼念]。
Pub Date : 2024-08-06
Joakim Dillner

HPV 18 caused 19  percent of all cervical cancer cases in Sweden, in particular adenocarcinomas. High vaccination coverages are required to eliminate the most oncogenic HPV types like HPV 16 and HPV 18, while medium-oncogenic viruses such as HPV 31, 33, 45, 52, and 58 are easier to eliminate due to their lower reproduction number. Women born 1994-1998 were offered catch-up vaccination against HPV 16 and HPV 18 at ages 13-18, but only about 55 percent participated, which is insufficient to eliminate these viruses. Offering vaccination against HPV 16, 18, 31, 33, 45, 52, and 58 to women born in 1994-1998 and achieving around 70 percent participation should eliminate the medium-oncogenic viruses and achieve population immunity also for HPV 16/18. A national project offering free vaccines and screening against these HPV types is ongoing since 2021. Already at the start of the project, there was only a single case of HPV 18 in age groups with high vaccination coverage, implying that extinction of this virus is imminent.

在瑞典,19% 的宫颈癌病例是由 HPV 18 引起的,尤其是腺癌。要消灭致癌性最强的 HPV 类型,如 HPV 16 和 HPV 18,需要较高的疫苗接种覆盖率,而中等致癌性的病毒,如 HPV 31、33、45、52 和 58,由于繁殖数量较少,则更容易消灭。1994-1998 年出生的女性在 13-18 岁时可接种 HPV 16 和 HPV 18 的补种疫苗,但只有约 55% 的人接种,不足以消灭这些病毒。如果为 1994-1998 年出生的女性提供 HPV 16、18、31、33、45、52 和 58 疫苗接种,并达到约 70% 的参与率,那么就能消灭中等致癌病毒,并实现对 HPV 16/18 的群体免疫。自 2021 年起,一个针对这些 HPV 类型提供免费疫苗和筛查的国家项目正在进行中。在项目开始时,疫苗接种覆盖率高的年龄组中只有一例人乳头瘤病毒 18,这意味着这种病毒即将灭绝。
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