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The “Neglected aVR Lead”:  Kounis Syndrome of MINOCA Type, Severe Left Main or 3-Vessel Disease and Type A Dissecting Ascending Aortic Aneurysm 被忽视的 aVR 导联": MINOCA 型库尼综合征、严重左主干或三支血管疾病和 A 型夹层升主动脉瘤
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.22352
Nicholas Kounis
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引用次数: 0
Evaluating the Long-Term Neurologic Sequelae Among Trauma Patients who Received Flexion-Extension Radiographs 评估接受屈伸射线照相术的创伤患者的长期神经系统后遗症
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.21379
Shelby Durler, Kelly L. Lightwine, Elizabeth Ablah, Thomas Cox, James M Haan
Introduction. This study evaluated the presence of neurologic sequelae among trauma patients after flexion-extension (F/E) radiographs. Methods. Authors of the study conducted a retrospective review of patients (age ≥ 14 years) with a Glasgow Coma Score of 15 who sustained a blunt traumatic injury and received F/E radiographs. Radiographic scans were defined as positive, negative, inconclusive, or incomplete. The neurologic status of each patient was assessed before and after the F/E radiographs, and at discharge and follow-up.Results. Of the 501 patients included in the analysis, 84.6% (n = 424) had negative F/E radiographs, and 3.2% (n = 16) had positive F/E radiographs. Ten percent (n = 51) of patients had incomplete F/E radiographs, and 2.0% (n = 10) were inconclusive due to the inability to rule out a ligamentous injury. Three patients (0.6%) had MRI-confirmed ligamentous injuries, all of which had initial incomplete F/E radiographs due to pain. No patient had a documented neurological deficit before or after the F/E exam. Three patients with an initial negative F/E radiograph returned to the clinic with symptoms of neurologic sequelae. Two of these patients had symptom resolution with no further issues at future follow-up appointments. The third patient was found to have chronic neurologic symptoms after further evaluation.Conclusions. The inclusion of F/E exams in cervical spine clearance protocols did not demonstrate any new long-term iatrogenic neurologic injuries. Consideration should be given to performing MRIs on patients with incomplete F/E radiographs that cannot rule out a ligamentous injury. 
简介本研究评估了外伤患者在接受屈伸(F/E)X光检查后是否存在神经系统后遗症。方法。该研究的作者对格拉斯哥昏迷评分为 15 分的钝性外伤患者(年龄≥ 14 岁)进行了回顾性审查,这些患者接受了 F/E 放射摄影。放射扫描结果被定义为阳性、阴性、不确定或不完整。每个患者的神经系统状况都在接受 F/E 影像学检查前后、出院时和随访时进行了评估。在纳入分析的 501 名患者中,84.6%(n = 424)的 F/E 放射线检查结果为阴性,3.2%(n = 16)的 F/E 放射线检查结果为阳性。10%的患者(n = 51)的F/E X光片不完整,2.0%的患者(n = 10)因无法排除韧带损伤而无法得出结论。三名患者(0.6%)的核磁共振成像结果证实为韧带损伤,所有这些患者最初都因疼痛而接受了不完整的 F/E 影像学检查。在进行 F/E 检查之前或之后,没有患者出现有记录的神经功能缺损。有三名患者最初的 F/E 影像学检查结果为阴性,但因出现神经系统后遗症症状而返回诊所。其中两名患者的症状得到了缓解,在以后的复诊中也没有再出现问题。第三位患者在进一步评估后发现有慢性神经系统症状。在颈椎清创方案中纳入 F/E 检查并未显示出任何新的长期先天性神经损伤。对于无法排除韧带损伤的不完整 F/E 影像学检查患者,应考虑进行核磁共振成像检查。
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引用次数: 0
Vaginal Cuff Dehiscence after Robotic Hysterectomy in Endometrial Cancer vs. Non-Cancer Patients 子宫内膜癌与非癌症患者机器人子宫切除术后的阴道袖带开裂问题
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.21651
Paige Nichols, Adrienne Esposito, Maria Kolojeski, Jennifer Keomany, Hayrettin Okut, Jacqueline Morgan, Kevin Miller
Introduction: Vaginal cuff dehiscence (CD) after hysterectomy is a relatively uncommon but potentially serious complication of robotic-assisted laparoscopic total hysterectomy (RLTH), which is performed for benign and malignant indications. This study aimed to determine if there is a difference in the incidence and risk factors of CD following RLTH among patients with endometrial cancer compared to patients without endometrial cancer.Methods: This retrospective study included women 18 years or older who underwent RLTH performed by one of two surgeons from a single institution from 2013 through 2018. Patients who underwent conversion to laparotomy, chemotherapy and/or radiation within a year before or after RLTH, and with malignancies other than uterine cancer were excluded. Data were abstracted from patient medical records.Results: Of 950 patients meeting inclusion criteria, 50.7% (n=482) had endometrial cancer. CD was reported in 2.5% (n=24) of all patients. While controlling for other variables, obese patients were 25.1% less likely than non-obese patients to experience CD (p=.011). Additionally, CD was 2.8 times more likely to occur when surgery was performed by surgeon A compared to surgeon B (p=0.027). No other variables (cancer status, age, sexual activity after surgery, distance from home to location of surgery, time interval from surgery to loss to follow-up) predicted CD.Conclusions: Endometrial cancer patients were not at greater risk of experiencing CD compared to non-cancer patients. Surgeon differences and BMI were associated with incidence of CD, and patients with a normal BMI were most likely to report experiencing CD.
导言:子宫切除术后阴道袖带开裂(CD)是机器人辅助腹腔镜全子宫切除术(RLTH)的一种相对少见但潜在的严重并发症,RLTH适用于良性和恶性适应症。本研究旨在确定子宫内膜癌患者与非子宫内膜癌患者相比,RLTH术后CD的发生率和风险因素是否存在差异:这项回顾性研究纳入了2013年至2018年期间由一家机构的两名外科医生之一实施RLTH手术的18岁或18岁以上女性。排除了在RLTH前后一年内接受开腹手术、化疗和/或放疗的患者,以及患有子宫癌以外的恶性肿瘤的患者。数据摘自患者病历:在符合纳入标准的 950 名患者中,50.7%(n=482)患有子宫内膜癌。在所有患者中,2.5%(24 人)患有子宫内膜癌。在控制其他变量的情况下,肥胖患者发生子宫内膜癌的几率比非肥胖患者低 25.1%(p=.011)。此外,与外科医生 B 相比,由外科医生 A 进行手术的患者发生 CD 的几率是后者的 2.8 倍(p=0.027)。其他变量(癌症状况、年龄、手术后的性活动、从家中到手术地点的距离、从手术到失去随访的时间间隔)都不能预测CD的发生:与非癌症患者相比,子宫内膜癌患者发生子宫内膜异位症的风险并不大。外科医生的差异和体重指数与子宫内膜异位症的发生率有关,体重指数正常的患者最有可能出现子宫内膜异位症。
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引用次数: 0
A Case of Extensive Cholangiocarcinoma Highlighting Challenges in Diagnosis and Treatment 一例广泛性胆管癌病例凸显诊断和治疗难题
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.21875
Wissam Karam, Timothy Nguyen, William Salyers
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引用次数: 0
Ethical Obligation of Adequate Pain Management in Long Term Care Residents with Dementia 对患有痴呆症的长期护理住院患者进行适当疼痛管理的伦理义务
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.22135
Donna Ewy
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引用次数: 0
A Case Report of Leclercia adecarboxylata Pyogenic Arthritis 一个关于十八烷基莱克菌化脓性关节炎的病例报告
Pub Date : 2024-07-24 DOI: 10.17161/kjm.vol17.20588
Hitanshu Dave, Lawrence Zhou, Deva Zamzow, Robert Wittler
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引用次数: 0
Identifying Opportunities for Impact of Community-Based Pharmacist-Led Biometric Health Screenings on ASCVD Risk. 确定社区药剂师主导的生物计量健康筛查对急性心血管疾病风险影响的机会。
Pub Date : 2023-04-24 eCollection Date: 2023-01-01 DOI: 10.17161/kjm.vol16.18514
Bradley J Newell, Ashley M Kells, Amy D Robertson, Tasha M Braun, Kimberly S Ward, Brent J Rohling, Brittany L Melton

Introduction: Community-based pharmacists are positioned uniquely to assist in the early detection of underlying cardiovascular disease (CVD) which affects approximately 50% of adults in the United States. Organizations utilize community-based pharmacists to conduct annual biometric health screenings to help employees identify health risks previously undetected. The goal of this study was to evaluate how community-based pharmacists could impact lifetime atherosclerotic cardiovascular disease (ASCVD) risk for a large population.

Methods: This study was a retrospective analysis of annual pharmacist-led 15-minute biometric health screening data from a large regional community-based pharmacy chain. Employees between the ages of 20 and 79 who had completed at least three biometric health screenings between July 1, 2015 and June 30, 2020 were included. Incomplete biometric health screening records were excluded. To calculate lifetime ASCVD risk and identify perceived gaps in care, prescription fill history of study participants was used. The pharmacists did not make clinical interventions; however, education was provided with the information found.

Results: A total of 10,001 patients were included. Median baseline ASCVD risk was 1.5% and increased to 1.8% (p < 0.001). Additionally, 1,187 patients with an elevated ASCVD risk ≥ 7.5%, showed statistically significant improvements in blood pressure, body mass index, and cholesterol.

Conclusions: Improvements for high-risk patients were seen in several biometric health screening parameters including blood pressure, body mass index, and cholesterol. Community-based pharmacists were well positioned to intervene clinically to support reduction of ASCVD life-time risk.

导言:美国约有 50% 的成年人患有潜在的心血管疾病 (CVD),而社区药剂师在协助及早发现这种疾病方面具有得天独厚的优势。各组织利用社区药剂师开展年度生物计量健康筛查,帮助员工识别以前未被发现的健康风险。本研究的目的是评估社区药剂师如何影响大量人群终生罹患动脉粥样硬化性心血管疾病(ASCVD)的风险:本研究是对一家大型地区性社区连锁药店每年由药剂师指导的 15 分钟生物特征健康筛查数据进行的回顾性分析。研究对象包括在 2015 年 7 月 1 日至 2020 年 6 月 30 日期间完成至少三次生物特征健康筛查的 20 至 79 岁的员工。不包括不完整的生物特征健康检查记录。为了计算终生 ASCVD 风险并找出护理方面的认知差距,研究人员使用了研究参与者的处方配药史。药剂师没有进行临床干预,但根据发现的信息进行了教育:共纳入 10,001 名患者。基线 ASCVD 风险中位数为 1.5%,后增至 1.8%(p < 0.001)。此外,有 1,187 名 ASCVD 风险≥ 7.5%的患者的血压、体重指数和胆固醇在统计学上有显著改善:结论:高风险患者的血压、体重指数和胆固醇等多项生物计量健康检查指标均有所改善。社区药剂师能够很好地进行临床干预,支持降低急性心血管疾病的终生风险。
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引用次数: 0
Physician Dispositions Toward Noninvasive Non-Hormonal Contraception. 医生对非侵入性非激素避孕的态度。
Pub Date : 2023-04-24 eCollection Date: 2023-01-01 DOI: 10.17161/kjm.vol16.18958
Alexandra V Davidson, Faith M Butler

Introduction: Evidence-based, nonbiased, counseling on contraceptive options, followed by shared decision-making, is key in facilitating reproductive justice in a diverse population. An estimated 3% of contraceptive users in the United States use fertility awareness-based methods (FABMs) for contraception, and demand for these methods is increasing. FABMs can be a highly effective form of family planning when used in accordance with evidence-based protocols. They are preferred by some patients due to medical contraindications to hormonal contraceptives, lack of side effects, religious convictions, preference to avoid hormones or contraceptive devices, improved body literacy, or a combination of the above. FABMs are infrequently covered in medical school curricula and are often perceived by physicians to be of low efficacy. There is an opportunity for improvement of physicians' evidence-based knowledge of FABMs, which has the potential to improve patient understanding of and access to the full menu of family planning options.

Methods: A self-administered, cross-sectional survey was distributed to assess physician knowledge and opinions of FABMs by key university contacts. Univariate and bivariate statistics were calculated for close-ended questions and responses to open-ended questions were analyzed for common themes.

Results: A total of 79 participants completed the entire survey. Another 11 submitted partially completed surveys. For completed surveys, questions assessing knowledge of key concepts underlying FABMs, performance by specialty was 55% correct for OB/GYN (n = 16), 55% (n = 47) correct for family medicine, 36% (n = 10) correct for internal medicine, and 35% (n = 6) correct for pediatrics. Negative, neutral, mixed, and positive opinions related to FABMs were represented.

Conclusions: There are opportunities to improve physicians' evidence-based knowledge of FABMs; this may improve patient-centered contraceptive care.

导言:以证据为基础、无偏见的避孕选择咨询以及共同决策是促进不同人群生殖公正的关键。在美国,估计有 3% 的避孕药具使用者使用基于生育意识的避孕方法(FABMs)进行避孕,而且对这些方法的需求正在不断增加。如果按照循证方案使用,生育觉醒避孕法是一种非常有效的计划生育方法。一些患者由于对激素避孕药有禁忌症、缺乏副作用、宗教信仰、不想使用激素或避孕药具、身体知识的提高或上述因素的综合作用而选择使用这些方法。医学院的课程中很少涉及 FABMs,而且医生往往认为其疗效不佳。医生有机会提高对 FABMs 的循证知识,这有可能改善患者对计划生育全套方案的理解和使用:方法:通过主要的大学联系人分发了一份自填式横截面调查表,以评估医生对 FABMs 的了解和看法。对封闭式问题进行了单变量和双变量统计,并对开放式问题的回答进行了共同主题分析:共有 79 位参与者完成了整个调查。另有 11 人提交了部分完成的调查问卷。在已完成的调查问卷中,对于评估 FABMs 基础关键概念知识的问题,各专科的正确率分别为:妇产科 55%(n = 16),全科 55%(n = 47),内科 36%(n = 10),儿科 35%(n = 6)。与 FABM 相关的意见有消极、中立、混合和积极四种:结论:有机会提高医生对 FABM 的循证知识;这可能会改善以患者为中心的避孕护理。
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引用次数: 0
A Case Series of Spouses Undergoing Rapid Micro-Induction Technique of Buprenorphine Initiation from Methadone. 配偶从美沙酮开始接受丁丙诺啡快速微量诱导技术的病例系列。
Pub Date : 2023-03-15 eCollection Date: 2023-01-01 DOI: 10.17161/kjm.vol16.18433
Kyle R Rampetsreiter, Iryna Salapenka, Jaya Sri Konakanchi, Jordan Anders, Roopa Sethi
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引用次数: 0
Managing Post-Operative Pain in Orthopedic Patients: An International Comparison. 矫形外科患者术后疼痛的处理:国际比较。
Pub Date : 2023-02-21 eCollection Date: 2023-01-01 DOI: 10.17161/kjm.vol16.18744
Jack M Ayres, Johnathan Dallman, Jack A Nolte, Nicholas Higginbotham, Jordan Baker, Greg Horton, Jonathon Salava, John Sojka, Kimberly J Templeton, Radu Ioan Malancea, Archie Heddings

Introduction: Opioids play a crucial role in post-operative pain management in America, but not in some other countries. We sought to determine if a discrepancy in opioid use between the United States (U.S.) and Romania, a country that administers opioids in a conservative fashion, would show in subjective pain control differences.

Methods: Between May 23, 2019, and November 23, 2019, 244 Romanian patients and 184 American patients underwent total hip arthroplasty or the surgical treatment of the following fractures: bimalleolar ankle, distal radius, femoral neck, intertrochanteric, and tibial-fibular. Opioid and non-opioid analgesic medication use and subjective pain scores during the first and second 24 hours after surgery were analyzed.

Results: Subjective pain scores for the first 24 hours were higher among patients in Romania compared to the U.S. (p < 0.0001), but Romanians reported lower pain scores than U.S. patients in the second 24-hours (p < 0.0001). The quantity of opioids given to U.S. patients did not differ significantly based on sex (p = 0.4258) or age (p = 0.0975). However, females reported higher pain scores than male patients following the studied procedures (p = 0.0181). No sex-based differences in pain scores were noted among Romanian patients.

Conclusions: Higher pain scores in American females, despite equivalent amounts of narcotics to their male counterparts, and the absence of a difference in Romanians suggested that the current American post-operative pain regimen may be tailored to the needs of male patients. In addition, it pointed to the impacts of gender, compared to sex, in pain experiences. Future research should look for the safest, most efficacious pain regimen suitable for all patients.

导言:在美国,阿片类药物在术后疼痛治疗中发挥着至关重要的作用,但在其他一些国家却并非如此。我们试图确定美国和罗马尼亚(一个以保守方式使用阿片类药物的国家)在阿片类药物使用上的差异是否会在主观疼痛控制上表现出来:2019年5月23日至2019年11月23日期间,244名罗马尼亚患者和184名美国患者接受了全髋关节置换术或以下骨折的手术治疗:双侧踝关节、桡骨远端、股骨颈、转子间骨折和胫腓骨骨折。对阿片类和非阿片类镇痛药物的使用情况以及术后第一和第二个24小时的主观疼痛评分进行了分析:结果:与美国相比,罗马尼亚患者在术后前24小时的主观疼痛评分更高(P < 0.0001),但罗马尼亚患者在术后后24小时的疼痛评分低于美国患者(P < 0.0001)。美国患者的阿片类药物用量因性别(p = 0.4258)或年龄(p = 0.0975)而无显著差异。不过,在所研究的手术后,女性患者的疼痛评分高于男性患者(p = 0.0181)。罗马尼亚患者的疼痛评分没有性别差异:结论:尽管麻醉剂用量与男性患者相当,但美国女性患者的疼痛评分较高,而罗马尼亚患者的疼痛评分则没有差异,这表明目前美国的术后疼痛治疗方案可能是根据男性患者的需求量身定制的。此外,该研究还指出了性别对疼痛体验的影响。未来的研究应寻找适合所有患者的最安全、最有效的止痛方案。
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引用次数: 0
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Kansas Journal of Medicine
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