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[Treatment of the non-functioning hypophyseal adenoma]. 无功能垂体腺瘤的治疗。
Pub Date : 1993-11-01
R Comtois, H Beauregard, M Somma, E Rasio, O Serri, N Aris-Jilwan, A Boucher, J Hardy

Non-functioning pituitary adenoma is a lesion usually large enough to produce loss of vision and often loss of libido. Transsphenoidal microsurgery is the treatment of choice of these patients. Postoperative radiation therapy should be performed in patients with significant residual pituitary adenoma. Some studies have recently reported that somatostatin analogue may be useful as adjuvant medical therapy, at least in order to improve visual field defects.

无功能垂体腺瘤是一种通常大到足以造成视力丧失和性欲丧失的病变。经蝶窦显微手术是这些患者的治疗选择。有明显垂体腺瘤残留的患者术后应行放射治疗。一些研究最近报道,生长抑素类似物可能是有用的辅助医学治疗,至少为了改善视野缺陷。
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引用次数: 0
[The treatment of prolactinoma]. 【催乳素瘤的治疗】。
Pub Date : 1993-11-01
O Serri, M Somma, H Beauregard, E Rasio, R Comtois, N Aris-Jilwan, A Boucher, J Hardy

Prolactinoma is the most common type of secretory pituitary tumor. The clinical presentation varies with age and sex, and the size of the adenoma. The differential diagnosis with nonfunctioning adenoma and hyperprolactinemia is particularly important in selecting an appropriate therapy. The choice of therapy depends on a number of factors including the patient's preference. In cases of radiologically undetectable microprolactinomas, we prefer observation only. However, hypogonadic patients are treated with bromocriptine. Generally, it is our recommendation that almost all of the patients with micro--and macroprolactinomas undergo a primary medical therapy, provided they are willing to continue such therapy on a long term basis. We recommend transsphenoidal surgery for patients who refuse long term medical therapy and in rare cases of prolactinomas which are unresponsive to medical therapy. We also consider surgery as a valuable alternative to medical therapy in patients with microprolactinomas and prolactin below 200 micrograms/L.

泌乳素瘤是最常见的垂体分泌性肿瘤。临床表现因年龄、性别和腺瘤大小而异。无功能腺瘤和高泌乳素血症的鉴别诊断在选择合适的治疗方法时尤为重要。治疗的选择取决于许多因素,包括患者的偏好。对于放射学上无法检测到的微泌乳素瘤,我们建议只进行观察。然而,性腺功能低下的患者用溴隐亭治疗。一般来说,我们建议几乎所有的微泌乳素瘤和巨泌乳素瘤患者接受初级药物治疗,前提是他们愿意长期继续这种治疗。对于拒绝长期药物治疗的患者和对药物治疗无反应的罕见催乳素瘤,我们推荐经蝶窦手术。我们也认为,对于微催乳素瘤和催乳素低于200微克/升的患者,手术是一种有价值的替代药物治疗的方法。
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引用次数: 0
[In cardiology: no miracles, but regression of mortality with therapeutic options that multiply]. [在心脏病学:没有奇迹,但死亡率的回归与治疗方案成倍增加]。
Pub Date : 1993-09-01
D Roy
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引用次数: 0
[Hyperthyroidism in a young, female patient]. [1例年轻女性甲状腺机能亢进]。
Pub Date : 1993-09-01
F Massoud, R Comtois
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引用次数: 0
[New strategies of the Medical Research Council of Canada]. [加拿大医学研究理事会的新战略]。
Pub Date : 1993-09-01
H A Ménard
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引用次数: 0
[Peer review: the more it changes...]. [同行评议:变化越大…]。
Pub Date : 1993-09-01
W D Seufert
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引用次数: 0
[Pregnant women's knowledge of prematurity in Quebec]. 【魁北克孕妇对早产的认识】。
Pub Date : 1993-09-01
M Labrecque, J Martin, J M Moutquin, S Marcoux, S Gingras

The objective of this study was to determine pregnant women's knowledge level concerning premature birth. During July of 1990, 465 pregnant women completed a questionnaire evaluating their knowledge of the following dimensions of premature birth: risk factors, symptoms, epidemiology, prevention and self-assessment of risk. The subjects were all francophones, at 16 weeks of less of pregnancy, with characteristics comparable to all pregnant women in Quebec. The study participants considered premature birth to be a serious health problem, and over-estimated the premature birth rate. Fifty-seven percent thought that the rate was 17% or greater. Eighty percent associated premature birth with some morbidity and mortality risks. On the other hand, the risk factors concerning premature birth were poorly known; approximately 50% of the women did not recognize twin pregnancy and a past history of premature delivery as risk factors. Moreover, a third of the women did not recognize the signs and symptoms of premature rupture of membranes and of premature labor. In conclusion, a high proportion of pregnant women in Quebec do not have even minimally adequate knowledge levels concerning the prevention or risks of premature birth.

本研究的目的是确定孕妇关于早产的知识水平。1990年7月,465名孕妇完成了一份调查问卷,评估她们对以下早产方面的知识:风险因素、症状、流行病学、预防和风险自我评估。研究对象都是说法语的,怀孕不到16周,与魁北克所有孕妇的特征相似。研究参与者认为早产是一个严重的健康问题,并高估了早产率。57%的人认为该比率为17%或更高。80%的人将早产与一些发病率和死亡率风险联系起来。另一方面,人们对早产的风险因素知之甚少;大约50%的妇女没有认识到双胎妊娠和过去的早产史是危险因素。此外,三分之一的妇女没有认识到胎膜早破和早产的迹象和症状。总之,魁北克省有很大比例的孕妇对预防早产或早产风险甚至没有最低限度的充分知识。
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引用次数: 0
[Food poisoning caused by a chemical product]. [由化学产品引起的食物中毒]。
Pub Date : 1993-09-01
C Gaulin
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引用次数: 0
[Perceptions of mental illness in Quebec residents]. [魁北克居民对精神疾病的看法]。
Pub Date : 1993-09-01
Y Lamontagne

A transverse survey was conducted with 772 Quebecers in September 1992. Its purpose was to evaluate the level of awareness of the general public about mental illness, the general knowledge of these illnesses and their treatments and the attitudes towards mentally ill patients. Results show that half of the interviewed subjects still feel that they are not informed enough about mental illness and even well informed people have a poor general knowledge of mental illnesses and their treatments. Finally, more than 65% of the surveyed population show positive attitudes towards psychiatric patients, which seems to be an improvement in comparison with the past years. The author believes that physicians should give more information on mental illness and particularly on the role of drugs in the treatment of mentally ill patients. It seems also important to put more emphasis on information to low and middle class people.

1992年9月对772名魁北克人进行了横向调查。其目的是评估公众对精神疾病的认识程度、对这些疾病及其治疗的一般知识以及对精神病患者的态度。结果显示,一半的受访者仍然觉得他们对精神疾病的了解不够,即使是知情的人对精神疾病及其治疗的一般知识也很差。最后,超过65%的被调查者对精神病患者表现出积极的态度,这似乎与过去几年相比有所改善。提交人认为,医生应该提供更多关于精神疾病的信息,特别是关于药物在治疗精神病患者中的作用。对中低阶层的人来说,重视信息也很重要。
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引用次数: 0
[Arms control: a question of public health]. [军备控制:一个公共卫生问题]。
Pub Date : 1993-09-01
H Rathjen, J F Chicoine
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引用次数: 0
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