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Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery最新文献

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[Isolated metastasis of the ascending ramus of the mandible of thyroid follicular carcinoma: a case report]. [甲状腺滤泡癌下颌骨升支孤立性转移1例报告]。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.012
Siyao Zhang, Qingjia Sun, Dongdong Zhu

The mandibular metastatic spread of carcinoma from the thyroid gland is exceedingly rare. Follicular thyroid carcinoma is the second most common type of thyroid carcinoma,accounting for approximately 10% to 15% of all thyroid cancers. The prognosis of FTC is relatively satisfactory. Due to its rich blood transport, it is easy to metastasize hematological, with the main sites of metastasis are bone and lung. However,mandibular metastasis of thyroid follicular carcinoma is rare. We report a case of thyroid follicular carcinoma that metastasized to the ascending ramus of the mandible 21 years after surgery.The operation was successfully completed, and there was no recurrence during postoperative follow-up. Due to the absence of obvious clinical symptoms in the patient, the diagnosis and treatment were challenging. We have provided detailed radiographic and pathological images to facilitate understanding and discussion of the disease.

甲状腺癌的下颌转移性扩散极为罕见。滤泡性甲状腺癌是甲状腺癌中第二常见的类型,约占所有甲状腺癌的10%至15%。FTC的预后相对令人满意。由于其血液转运丰富,血液学易转移,主要转移部位为骨和肺。然而,甲状腺滤泡癌的下颌转移是罕见的。我们报告一例甲状腺滤泡癌,术后21年转移至下颌升支。手术顺利完成,术后随访无复发。由于患者没有明显的临床症状,诊断和治疗具有挑战性。我们提供了详细的放射学和病理学图像,以便于了解和讨论该疾病。
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引用次数: 0
[Strategy of the diagnosis and treatment for epistaxis and guideline for clinical application of MasterPillar]. [鼻出血的诊断和治疗策略及MasterPillar的临床应用指南]。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.003
Li Shi

Epistaxis is a common otorhinolaryngological emergency with complex etiological factors and varied clinical manifestations. The key to epistaxis treatment is accurate diagnosis and adequate hemostasis. Electrocoagulation is a reliable, safe and effective treatment for epistaxis. However, there are still several deficiencies in application of the commonly used electrocoagulation surgical products. This paper introduces a new type of radiofrequency head incorporating the dynamic circulatory functions of drip, irrigation, hemostasis and aspiration. We aim to achieve noninvasive, effective and accurate hemostasis in the treatment of epistaxis or nasal sinus surgery.

鼻出血是一种常见的耳鼻喉科急症,病因复杂,临床表现多样。鼻出血治疗的关键是准确诊断和充分止血。电凝治疗鼻出血是一种可靠、安全、有效的治疗方法。然而,目前常用的电凝外科产品在应用上还存在一些不足。本文介绍了一种新型射频头,它具有滴注、冲洗、止血、抽吸等动态循环功能。我们的目的是在鼻出血或鼻窦手术中实现无创、有效和准确的止血。
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引用次数: 0
[Effect of nasal swell body on nasal airflow and Artemisia pollen deposition]. 【鼻腔肿胀体对鼻腔气流和蒿属花粉沉积的影响】。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.006
Ya Zhang, Ruiping Ma, Yusheng Wang, Jingliang Dong, Jingbin Zhang, Zhenzhen Hu, Feilun Yang, Minjie Gong, Miao Lou, Lin Tian, Luyao Zhang, Botao Wang, Yuping Peng, Guoxi Zheng

Objective:The nasal swell body(NSB) consists of the nasal septal cartilage, nasal bone, and swollen soft tissue, all of which are visible during endoscopic and imaging examinations. Although the function of the NSB remains uncertain, there is evidence to suggest that it plays a vital role in regulating nasal airflow and filtering inhaled air. Based on anatomical and histological evidence, it is hypothesized that the NSB is indispensable in these processes. This study aims to investigate the impact of NSB on nasal aerodynamics and the deposition of allergen particles under physiological conditions. Methods:The three-dimensional (3D) nasal models were reconstructed from computed tomography (CT) scans of the paranasal sinus and nasal cavity in 30 healthy adult volunteers from Northwest China, providing basis for the construction of models without NSB following virtual NSB-removal surgery. To analyze the distribution of airflow in the nasal cavity, nasal resistance, heating and humidification efficiency, and pollen particle deposition rate at various anatomical sites, we employed the computed fluid dynamics(CFD) method for numerical simulation and quantitative analysis. In addition, we created fully transparent segmented nasal cavity models through 3D printing, which were used to conduct bionic experiments to measure nasal resistance and allergen particle deposition. Results:①The average width and length of the NSB in healthy adults in Northwest China were (12.85±1.74) mm and (28.30±1.92) mm, respectively. ②After NSB removal, there was no significant change in total nasal resistance, and cross-sectional airflow velocity remained essentially unaltered except for a decrease in topical airflow velocity in the NSB plane. ③There was no discernible difference in the nasal heating and humidification function following the removal of the NSB; ④After NSB removal, the deposition fraction(DF) of Artemisia pollen in the nasal septum decreased, and the DFs post-and pre-NSB removal were(22.79±6.61)% vs (30.70±12.27)%, respectively; the DF in the lower airway increased, and the DFs post-and pre-NSB removal were(24.12±6.59)% vs (17.00±5.57)%, respectively. Conclusion:This study is the first to explore the effects of NSB on nasal airflow, heating and humidification, and allergen particle deposition in a healthy population. After NSB removal from the healthy nasal cavities: ①nasal airflow distribution was mildly altered while nasal resistance showed no significantly changed; ②nasal heating and humidification were not significantly changed; ③the nasal septum's ability to filter out Artemisia pollen was diminished, which could lead to increased deposition of Artemisia pollen in the lower airway.

目的:鼻肿胀体(NSB)由鼻中隔软骨、鼻骨和肿胀的软组织组成,所有这些在内镜和影像学检查中都是可见的。尽管NSB的功能仍不确定,但有证据表明,它在调节鼻腔气流和过滤吸入空气方面发挥着至关重要的作用。根据解剖学和组织学证据,假设NSB在这些过程中是不可或缺的。本研究旨在研究生理条件下NSB对鼻腔空气动力学和过敏原颗粒沉积的影响。方法:对来自西北地区的30名健康成年志愿者的鼻窦和鼻腔进行计算机断层扫描,重建其三维鼻腔模型,为虚拟NSB切除术后无NSB模型的构建提供依据。为了分析鼻腔内气流的分布、鼻腔阻力、加热和加湿效率以及不同解剖部位的花粉颗粒沉积率,我们采用计算流体动力学(CFD)方法进行了数值模拟和定量分析。此外,我们通过3D打印创建了完全透明的分段鼻腔模型,用于进行仿生实验,以测量鼻腔阻力和过敏原颗粒沉积。结果:①西北地区健康成人NSB的平均宽度和长度分别为(12.85±1.74)mm和(28.30±1.92)mm去除NSB后,总鼻阻力没有显著变化,除NSB平面内局部气流速度下降外,横截面气流速度基本保持不变。③去除NSB后,鼻腔加热和加湿功能没有明显差异;④去除NSB后,蒿花粉在鼻中隔的沉积分数(DF)降低,去除NSB前后的DF分别为(22.79±6.61)%和(30.70±12.27)%;下呼吸道DF增加,NSB去除后和去除前的DF分别为(24.12±6.59)%和(17.00±5.57)%。结论:本研究首次探讨NSB对健康人群鼻腔气流、加热和加湿以及过敏原颗粒沉积的影响。从健康鼻腔中取出NSB后:①鼻腔气流分布轻度改变,鼻阻力无明显变化;②鼻腔加温、加湿无明显变化;③鼻中隔过滤青蒿花粉的能力减弱,这可能导致青蒿花粉在下呼吸道的沉积增加。
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引用次数: 0
[Treatment experience of neck tumor surgeries involving carotid artery]. 【颈动脉颈肿瘤手术治疗经验】。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.011
Zinian Wang, Jingzhe Li, Yuqi He, Tao Yu, Zhongliang Zhang, Qi Kang, Fei Gong, Yang Xia, Shanshan Xu

Objective:To investigate surgical treatment of carotid artery diseases in neck tumor surgery. Methods:A retrospective analysis of the clinical data on carotid artery treatment was conducted in the five cases of neck tumor surgeries treated at Department of Surgical Oncology, the First Peoples Hospital of Lanzhou from March 2010 to May 2020. Surgical methods, including carotid artery resection and ligation, tumor-involved artery resection and vascular reconstruction, and tumor peeling and carotid rupture repairing were used, respectively. Results:Five cases were successfully operated on. One case of carotid artery ligation was followed by intermittent dizziness and decreased contra-lateral limb strength after the surgery. The remaining patients exhibited no neurological complications. A patient with cervical low-grade myofibroblastoma developed into lung metastases 8 months after the surgery. Another patient with cervical lymph node metastases in papillary thyroid cancer developed into lung metastases 24 months after the surgery. Conclusion:Currently, surgical methods for clinical treatment of diseased carotid arteries include carotid artery resection and ligation, simple tumor peeling, tumor invasion artery resection and vascular reconstruction, and interventional therapy. Each surgical method has its own advantages and disadvantages. Therefore, the choice of treatment depends on the patient's specific conditions, physician's clinical experience, and the equipment available.

目的:探讨颈部肿瘤手术中颈动脉疾病的外科治疗方法。方法:对兰州市第一人民医院肿瘤外科2010年3月至2020年5月收治的5例颈部肿瘤手术患者颈动脉治疗的临床资料进行回顾性分析。手术方法包括颈动脉切除结扎、肿瘤累及动脉切除重建、肿瘤剥离和颈动脉破裂修复。结果:成功手术5例,其中1例颈动脉结扎术后出现间歇性眩晕,对侧肢体力量下降。其余患者未出现神经系统并发症。一名颈部低级别肌纤维母细胞瘤患者在手术后8个月发展为肺转移。另一例癌症乳头状癌颈淋巴结转移患者在术后24个月发展为肺转移。结论:目前临床治疗颈动脉病变的手术方法包括颈动脉切除结扎、单纯肿瘤剥离、肿瘤侵犯动脉切除重建和介入治疗。每种手术方法都有其优点和缺点。因此,治疗的选择取决于患者的具体情况、医生的临床经验和可用的设备。
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引用次数: 0
[Progress in neural network mechanism of tinnitus using functional magnetic resonance imaging]. 【利用功能磁共振成像研究耳鸣神经网络机制的进展】。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.014
Kehui Ren, Hui Liu, Yujuan Wang, Wen Zhang, Ting Yang, Lili Xu

Tinnitus refers to the perception of abnormal sound in the absence of external sound stimulation. It can have an impact on a person's mood, memory, attention, and mental state, although the mechanism of tinnitus is still unclear. In recent years, the research on the central neural mechanism of tinnitus has attracted the attention of scholars.Functional magnetic resonance imaging (fMRI),as an effective imaging technology, has been actively employed in this field. This paper provides a systematic summary of studies on the central neural mechanism of tinnitus by fMRI in recent years,revealed the changes of functional connections among tinnitus-related neural networks,such as auditory network,limbic system,default mode network and salience network. The central neural mechanism of tinnitus involves multiple networks that interact with each other. By understanding this mechanism, we hope to develop more targeted prevention and treatment strategies to help patients alleviate long-term tinnitus.

耳鸣是指在没有外部声音刺激的情况下对异常声音的感知。它会对一个人的情绪、记忆、注意力和精神状态产生影响,尽管耳鸣的机制尚不清楚。近年来,对耳鸣中枢神经机制的研究引起了学者们的关注。功能磁共振成像(fMRI)作为一种有效的成像技术,在该领域得到了积极的应用。本文系统总结了近年来功能磁共振成像对耳鸣中枢神经机制的研究,揭示了耳鸣相关神经网络,如听觉网络、边缘系统、默认模式网络和显著性网络之间功能连接的变化。耳鸣的中枢神经机制涉及多个相互作用的网络。通过了解这一机制,我们希望制定更有针对性的预防和治疗策略,帮助患者缓解长期耳鸣。
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引用次数: 0
[A prospective study of the effect of functional endoscopic sinus surgery on the recovery of olfactory function in patients with chronic rhinosinusitis with nasal polyposis]. [功能性鼻内窥镜鼻窦手术对慢性鼻窦炎伴鼻息肉病患者嗅觉功能恢复影响的前瞻性研究]。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.007
Weijia DU, Shanguang Zhao, Xin Wei, Jian Wang, Tao Xue, Meihao Qi, Fuquan Chen

Objective:To investigate the efficacy of functional endoscopic sinus surgery(FESS) in the treatment of olfactory dysfunction in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) , at the same time, it provides an evidence for the prognosis evaluation of olfaction and the clinical application of oERPs to evaluate the plasticity of olfaction cortex. Methods:From October 2021 to October 2022, 45 patients with CRSwNP who underwent FESS nine-step standardized treatment in our department were recruited as the research subjects, divided into 22 patients with eosinophilic CRSwNP(ECRS)and 23 patients with non-eosinophilic CRSwNP(nECRS). VAS-olfactory dysfunction (VAS-OD) score, SNOT-22 olfactory score, Sniffin' Sticks test and oERPs collection and processing were performed before the operation. All items were evaluated again 3 months after the operation. Results:VAS-OD and SNOT-22 olfactory score were significantly lower in all CRSwNP patients after the operation than those before the operation[F(1, 43) =357.429, P<0.001; F(1, 43) =185.657, P<0.001], the scores of T, D, I and TDI scores in Sniffin' Sticks test were significantly higher than those before the operation[F(1, 43) =126.302, P<0.001; F(1, 43) =311.301, P<0.001; F(1, 43) =131.401, P<0.001; F(1, 43) =295.885, P<0.001]; The decrease of VAS-OD and SNOT-22 olfactory score in the ECRS group was smaller than that in the nECRS group[F(1, 43) =4.825, P=0.033; F(1, 43) =9.916, P=0.003], T, D and TDI scores were significantly lower in nECRS group than those in nECRS group[F(1, 43) =6.719, P=0.013; F(1, 43) =4.890, P=0.032; F(1, 43) =4.469, P=0.040]; There was a positive correlation between preoperative eosinophil-to-lymphocyte ratio(ELR) and SNOT-22 olfactory score and how much it changes(r=0.455, P=0.002; r=-0.414, P=0.005), a negative correlation between T, TDI score and how much they change respectively(r=-0.431, P=0.003; r=-0.385, P=0.009; r=-0.383, P=0.010; r=-0.316, P=0.035). The latency of P3 was significantly shorter after operation than that before operation in all CRSwNP patients[F(1, 14) =24.840, P<0.001], however, the amplitude has no significant surgical effect. Conclusion:FESS could significantly improve the olfactory function of CRSwNP patients, while changes in plasticity may occur in the olfactory cortex. In addition, the preoperative peripheral blood eosinophil granulocyte level can predict the postoperative olfactory improvement.

目的:探讨功能性鼻内镜手术(FESS)治疗慢性鼻窦炎伴鼻息肉(CRSwNP)患者嗅觉功能障碍的疗效,同时为嗅觉的预后评估和oERPs评估嗅觉皮层可塑性的临床应用提供依据。方法:从2021年10月至2022年10月,我们招募了45名在我科接受FESS九步标准化治疗的CRSwNP患者作为研究对象,分为22名嗜酸性CRSwNP(ECRS)患者和23名非嗜酸性CRSwNP(nCCRS)患者。术前进行VAS嗅觉功能障碍(VAS-OD)评分、SNOT-22嗅觉评分、Sniffin’Sticks试验和oERPs收集和处理。术后3个月再次对所有项目进行评估。结果:所有CRSwNP患者术后VAS-OD和SNOT-22嗅觉评分均显著低于术前[F(1,43)=357.429,PF(1,43=185.657,PF(1,43)=126.302,PF(1,33)=311.301,PF(1-43)=131.401,nCRS组的D和TDI评分显著低于nCRS组[F(1,43)=6.719,P=0.013;F(1,43=4.890,P=0.032;F(1,43)=4.469,P=0.040];术前嗜酸性粒细胞与淋巴细胞比率(ELR)和SNOT-22嗅觉评分及其变化程度呈正相关(r=0.455,P=0.002;r=-0.414,P=0.005),TDI评分及其变化程度(r=-0.431,P=0.003;r=-0.385,P=0.009;r=-0.383,P=0.010;r=-0.316,P=0.035)。所有CRSwNP患者术后P3潜伏期明显短于术前[F(1,14)=24.840,P结论:FESS可显著改善CRSwNP患者的嗅觉功能,而嗅觉皮层可能发生可塑性变化。此外,术前外周血嗜酸性粒细胞水平可以预测术后嗅觉的改善。
{"title":"[A prospective study of the effect of functional endoscopic sinus surgery on the recovery of olfactory function in patients with chronic rhinosinusitis with nasal polyposis].","authors":"Weijia DU, Shanguang Zhao, Xin Wei, Jian Wang, Tao Xue, Meihao Qi, Fuquan Chen","doi":"10.13201/j.issn.2096-7993.2023.07.007","DOIUrl":"10.13201/j.issn.2096-7993.2023.07.007","url":null,"abstract":"<p><p><b>Objective:</b>To investigate the efficacy of functional endoscopic sinus surgery(FESS) in the treatment of olfactory dysfunction in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) , at the same time, it provides an evidence for the prognosis evaluation of olfaction and the clinical application of oERPs to evaluate the plasticity of olfaction cortex. <b>Methods:</b>From October 2021 to October 2022, 45 patients with CRSwNP who underwent FESS nine-step standardized treatment in our department were recruited as the research subjects, divided into 22 patients with eosinophilic CRSwNP(ECRS)and 23 patients with non-eosinophilic CRSwNP(nECRS). VAS-olfactory dysfunction (VAS-OD) score, SNOT-22 olfactory score, Sniffin' Sticks test and oERPs collection and processing were performed before the operation. All items were evaluated again 3 months after the operation. <b>Results:</b>VAS-OD and SNOT-22 olfactory score were significantly lower in all CRSwNP patients after the operation than those before the operation[<i>F</i>(1, 43) =357.429, <i>P</i><0.001; <i>F</i>(1, 43) =185.657, <i>P</i><0.001], the scores of T, D, I and TDI scores in Sniffin' Sticks test were significantly higher than those before the operation[<i>F</i>(1, 43) =126.302, <i>P</i><0.001; <i>F</i>(1, 43) =311.301, <i>P</i><0.001; <i>F</i>(1, 43) =131.401, <i>P</i><0.001; <i>F</i>(1, 43) =295.885, <i>P</i><0.001]; The decrease of VAS-OD and SNOT-22 olfactory score in the ECRS group was smaller than that in the nECRS group[<i>F</i>(1, 43) =4.825, <i>P</i>=0.033; <i>F</i>(1, 43) =9.916, <i>P</i>=0.003], T, D and TDI scores were significantly lower in nECRS group than those in nECRS group[<i>F</i>(1, 43) =6.719, <i>P</i>=0.013; <i>F</i>(1, 43) =4.890, <i>P</i>=0.032; <i>F</i>(1, 43) =4.469, <i>P</i>=0.040]; There was a positive correlation between preoperative eosinophil-to-lymphocyte ratio(ELR) and SNOT-22 olfactory score and how much it changes(<i>r</i>=0.455, <i>P</i>=0.002; <i>r</i>=-0.414, <i>P</i>=0.005), a negative correlation between T, TDI score and how much they change respectively(<i>r</i>=-0.431, <i>P</i>=0.003; <i>r</i>=-0.385, <i>P</i>=0.009; <i>r</i>=-0.383, <i>P</i>=0.010; <i>r</i>=-0.316, <i>P</i>=0.035). The latency of P3 was significantly shorter after operation than that before operation in all CRSwNP patients[<i>F</i>(1, 14) =24.840, <i>P</i><0.001], however, the amplitude has no significant surgical effect. <b>Conclusion:</b>FESS could significantly improve the olfactory function of CRSwNP patients, while changes in plasticity may occur in the olfactory cortex. In addition, the preoperative peripheral blood eosinophil granulocyte level can predict the postoperative olfactory improvement.</p>","PeriodicalId":18104,"journal":{"name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery","volume":"37 7","pages":"542-549"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570099/pdf/lcebyhtjwkzz-37-7-542.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9959347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Surgical approach analysis of endoscopic resection of juvenile nasopharyngeal angiofibroma]. 【内镜下切除青少年鼻咽血管纤维瘤手术入路分析】。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.009
Xiaojie Xu, Ping Li, Xiaolang Jin, Yulin Zhao, Ying Wang

Objective:To investigate the surgical approach for the resection of juvenile nasopharyngeal angiofibroma(JNA) under nasal endoscopy. Methods:The clinical data of 87 patients undergoing endoscopic resection of nasopharyngeal fibroangioma were retrospectively analyzed. We classified JNA according to tumor site, size, invasion scope and anatomic position relationship between tumor and midline of pupil. Three endoscopic surgical approaches were selected according to the classification, and the postoperative symptoms, complications and recurrence were investigated and analyzed. Results:The tumor resection rate of 87 cases by nasal endoscopic surgery was 100%. Thirty-five cases were approached through the middle nasal passage(small tumors located in the nasal sinuses and pterygopalatine fossa), forty-five cases were approached through the lateral wall of the nasal cavity(tumor invaded the pterygopalatine fossa but did not exceed the midline of the pupil) , and seven cases were approached via the lateral wall of nasal cavity + ipsilateral anterior wall of maxillary sinus(tumor invaded the infratemporal fossa beyond the midline of pupil or invaded the cavernous sinus and the middle cranial fossa epidural), Postoperative patients with nasal congestion, nasal bleeding, headache, dizziness, vision loss and other symptoms showed varying degrees of improvement. No surgical death or intracranial infection occurred. The postoperative follow-up was 6-78 months, and the recurrence rate was 3.44%. Conclusion:Endoscopic resection of nasopharyngeal fibroangioma is the main treatment method for JNA. Selecting suitable endoscopic approach to resect JNA, To maximize the advantage of nasal endoscopic equipment according to the inherent anatomical space of the human nasal cavity, In order to achieve the purpose of JNA resection, reduce intraoperative and postoperative complications, reduce the recurrence rate and improve the prognosis.

目的:探讨鼻内镜下切除青少年鼻咽血管纤维瘤的手术方法。方法:回顾性分析87例鼻内镜下鼻咽纤维血管瘤切除术的临床资料。我们根据肿瘤的部位、大小、侵袭范围以及肿瘤与瞳孔中线的解剖位置关系对JNA进行了分类。根据分类选择三种内镜手术入路,并对术后症状、并发症和复发进行调查分析。结果:87例患者经鼻内镜手术切除肿瘤的成功率为100%。35例通过中鼻腔(位于鼻窦和翼腭窝的小肿瘤)接近,45例通过鼻腔侧壁接近(肿瘤侵犯翼腭窝但未超过瞳孔中线),7例经鼻腔侧壁+上颌窦同侧前壁接近(肿瘤侵犯瞳孔中线以外的颞下窝或侵犯海绵窦和中颅窝硬膜外),术后患者出现鼻塞、鼻出血、头痛、头晕、,视力下降等症状均有不同程度的改善。未发生手术死亡或颅内感染。术后随访6~78个月,复发率3.44%。结论:鼻内镜下切除鼻咽纤维血管瘤是治疗JNA的主要方法。选择合适的内窥镜入路切除JNA,根据人体鼻腔固有的解剖空间,最大限度地发挥鼻内窥镜设备的优势,以达到JNA切除的目的,减少术中和术后并发症,降低复发率,改善预后。
{"title":"[Surgical approach analysis of endoscopic resection of juvenile nasopharyngeal angiofibroma].","authors":"Xiaojie Xu, Ping Li, Xiaolang Jin, Yulin Zhao, Ying Wang","doi":"10.13201/j.issn.2096-7993.2023.07.009","DOIUrl":"10.13201/j.issn.2096-7993.2023.07.009","url":null,"abstract":"<p><p><b>Objective:</b>To investigate the surgical approach for the resection of juvenile nasopharyngeal angiofibroma(JNA) under nasal endoscopy. <b>Methods:</b>The clinical data of 87 patients undergoing endoscopic resection of nasopharyngeal fibroangioma were retrospectively analyzed. We classified JNA according to tumor site, size, invasion scope and anatomic position relationship between tumor and midline of pupil. Three endoscopic surgical approaches were selected according to the classification, and the postoperative symptoms, complications and recurrence were investigated and analyzed. <b>Results:</b>The tumor resection rate of 87 cases by nasal endoscopic surgery was 100%. Thirty-five cases were approached through the middle nasal passage(small tumors located in the nasal sinuses and pterygopalatine fossa), forty-five cases were approached through the lateral wall of the nasal cavity(tumor invaded the pterygopalatine fossa but did not exceed the midline of the pupil) , and seven cases were approached via the lateral wall of nasal cavity + ipsilateral anterior wall of maxillary sinus(tumor invaded the infratemporal fossa beyond the midline of pupil or invaded the cavernous sinus and the middle cranial fossa epidural), Postoperative patients with nasal congestion, nasal bleeding, headache, dizziness, vision loss and other symptoms showed varying degrees of improvement. No surgical death or intracranial infection occurred. The postoperative follow-up was 6-78 months, and the recurrence rate was 3.44%. <b>Conclusion:</b>Endoscopic resection of nasopharyngeal fibroangioma is the main treatment method for JNA. Selecting suitable endoscopic approach to resect JNA, To maximize the advantage of nasal endoscopic equipment according to the inherent anatomical space of the human nasal cavity, In order to achieve the purpose of JNA resection, reduce intraoperative and postoperative complications, reduce the recurrence rate and improve the prognosis.</p>","PeriodicalId":18104,"journal":{"name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery","volume":"37 7","pages":"556-561"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570105/pdf/lcebyhtjwkzz-37-7-556.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Giant myoepithelial carcinoma of the nuchal region: a case report and literature review]. 【颈部巨大肌上皮癌1例报告及文献复习】。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.013
Feng Liu, Jiang Chang, Baoyan Zhu, Lifang Lu, Jie Nan, Fei Han

Myoepithelioma, also known as malignant myoepithelioma, is a rare malignant tumor originating from myoepithelial cell. This article reports a patient with a huge tumor in the neck and left elbow who underwent fine needle aspiration under local anesthesia. The pathological diagnosis was a myoepithelioma. Under general anesthesia, giant tumors in the lower neck, posterior cranial fossa, neck, and left elbow were removed, and postoperative pathology showed that they were all myoepithelial tumors. Immunohistochemistry showed AE1/AE3 (+), P63 (+), CK7 (+), CK5 (+), and CD138 (+). The clinical characteristics and diagnosis and treatment process of this case are reported and relevant literature is reviewed.

肌上皮瘤又称恶性肌上皮瘤,是一种罕见的起源于肌上皮细胞的恶性肿瘤。本文报告一位颈部及左肘有巨大肿瘤的病人,在局部麻醉下接受细针抽吸。病理诊断为肌上皮瘤。在全身麻醉下,切除了下颈部、后颅窝、颈部和左肘的巨大肿瘤,术后病理显示均为肌上皮肿瘤。免疫组化显示AE1/AE3(+)、P63(+,CK7(+),CK5(+)和CD138(+)。报告该病例的临床特点、诊断和治疗过程,并复习相关文献。
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引用次数: 0
[A multi-center observation of the therapeutic efficacy of Bencycloquidium bromide in the treatment of seasonal allergic rhinitis with predominant symptoms of rhinorrhea]. [溴化苄环喹钠治疗以鼻漏为主要症状的季节性过敏性鼻炎疗效的多中心观察]。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.008
Weini Hu, Tianhong Zhang, Yinghong Zhang, Chao Meng, Lifeng Xie, Yu Song, Chen DU, Chiyu Xu, Yali DU, Qiang Zuo, Fengyang An, Yuhui Wang, Cuida Meng, Lei Zhang, Dongdong Zhu, Li Zhu

Objective:To observe the efficacy and safety of the M receptor antagonist Bencycloquidium bromide nasal spray in treatment of seasonal allergic rhinitis with runny nose as the main symptom. Methods:From August 2021 to September 2021, 134 patients with seasonal allergic rhinitis were enrolled in the otolaryngology Outpatient Department of Peking University Third Hospital, First Affiliated Hospital of Harbin Medical University and China-Japanese Friendship Hospital of Jilin University, including 71 males and 63 females, with a median age of 38 years. TNSS score and visual analogue scale(VAS) of total nasal symptoms were observed during 2 weeks of treatment with Bencycloquidium bromide nasal spray. Results:TNSS score decreased from (8.89±3.31) on day 0 to (3.71±2.51) on day 14(P<0.001), VAS score of nasal symptoms decreased from (24.86±7.40) on day 0 to (6.84±5.94) on day 14(P<0.001), VAS score of rhinorrhoea decreased from (6.88±2.06) on day 0 to (1.91±1.81) on day 14(P<0.001). Rhinoconjunctivitis quality of life questionnaire(RQLQ) score decreased from (94.63±33.35) on day 0 to (44.95±32.28) on day 14(P<0.001). The incidence of adverse reaction was low and no serious adverse events occurred during the whole experiment. Conclusion:Bencycloquidium bromide nasal spray has significant efficacy and good safety in the treatment of seasonal allergic rhinitis.

目的:观察M受体拮抗剂溴化苄环喹钠鼻喷雾剂治疗以流鼻涕为主要症状的季节性过敏性鼻炎的疗效和安全性。方法:2021年8月至2021年9月,北京大学第三医院、哈尔滨医科大学第一附属医院、吉林大学中日友好医院耳鼻喉科门诊134例季节性过敏性鼻炎患者,其中男性71例,女性63例,中位年龄38岁。在溴化苄环喹钠鼻喷雾剂治疗的2周内,观察TNSS评分和总鼻症状的视觉模拟评分(VAS)。结果:TNSS评分由第0天的(8.89±3.31)降至第14天的(3.71±2.51)(PPPPC)。
{"title":"[A multi-center observation of the therapeutic efficacy of Bencycloquidium bromide in the treatment of seasonal allergic rhinitis with predominant symptoms of rhinorrhea].","authors":"Weini Hu, Tianhong Zhang, Yinghong Zhang, Chao Meng, Lifeng Xie, Yu Song, Chen DU, Chiyu Xu, Yali DU, Qiang Zuo, Fengyang An, Yuhui Wang, Cuida Meng, Lei Zhang, Dongdong Zhu, Li Zhu","doi":"10.13201/j.issn.2096-7993.2023.07.008","DOIUrl":"10.13201/j.issn.2096-7993.2023.07.008","url":null,"abstract":"<p><p><b>Objective:</b>To observe the efficacy and safety of the M receptor antagonist Bencycloquidium bromide nasal spray in treatment of seasonal allergic rhinitis with runny nose as the main symptom. <b>Methods:</b>From August 2021 to September 2021, 134 patients with seasonal allergic rhinitis were enrolled in the otolaryngology Outpatient Department of Peking University Third Hospital, First Affiliated Hospital of Harbin Medical University and China-Japanese Friendship Hospital of Jilin University, including 71 males and 63 females, with a median age of 38 years. TNSS score and visual analogue scale(VAS) of total nasal symptoms were observed during 2 weeks of treatment with Bencycloquidium bromide nasal spray. <b>Results:</b>TNSS score decreased from (8.89±3.31) on day 0 to (3.71±2.51) on day 14(<i>P</i><0.001), VAS score of nasal symptoms decreased from (24.86±7.40) on day 0 to (6.84±5.94) on day 14(<i>P</i><0.001), VAS score of rhinorrhoea decreased from (6.88±2.06) on day 0 to (1.91±1.81) on day 14(<i>P</i><0.001). Rhinoconjunctivitis quality of life questionnaire(RQLQ) score decreased from (94.63±33.35) on day 0 to (44.95±32.28) on day 14(<i>P</i><0.001). The incidence of adverse reaction was low and no serious adverse events occurred during the whole experiment. <b>Conclusion:</b>Bencycloquidium bromide nasal spray has significant efficacy and good safety in the treatment of seasonal allergic rhinitis.</p>","PeriodicalId":18104,"journal":{"name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery","volume":"37 7","pages":"550-555"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570111/pdf/lcebyhtjwkzz-37-7-550.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of mouth breathing on upper airway structure in patients with obstructive sleep apnea]. [口腔呼吸对阻塞性睡眠呼吸暂停患者上呼吸道结构的影响]。
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.13201/j.issn.2096-7993.2023.07.005
Yanru Li, Nanxi Fei, Lili Cao, Yunhan Shi, Junfang Xian

Objective:To compare the changes of morphology of pharynx in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and healthy individuals during oral or nasal breathing, and explore the relevant influencing factors. Methods:Twenty-nine adult patients with OSAHS and 20 non-snoring controls underwent MRI to obtain upper airway structural measurements while the subjects were awake and during mouth breathing with a nasal clip.The following were analyzed. ①The changes of upper airway structure of oral and nasal respiration in non-snoring control/OSAHS patients were observed; ②The differences and influencing factors of upper airway structure changes between OSAHS patients and controls were compared during breathing. Results:The control group consisted of 15 males and 5 females, with an apnea-hypopnea index (AHI)<5 events/h, while the OSAHS group comprised 26 males and 3 females with an AHI of 40.4±23.1 events/h and the mean lowest arterial oxygen saturation (LSaO2) was 79.5% ±10.0%. In the both groups, the vertical distance between the mandible and the posterior pharyngeal wall decreased (P<0.05); The long axis of tongue body decreased (P<0.05), and the contact area between tongue and palate decreased. There was no significant change in the total volume of the retropalatine(RP) and retroglossal(RG) airway in the control group (P>0.05). However, the minimum cross-sectional area and volume of the RP airway in OSAHS decreased (P<0.001). The lateral diameters of uvula plane in OSAHS decreased during mouth breathing, which was contrary to the trend in the control group (P=0.017). The AHI of patients was positively correlated with the reduction of the volume of the RP airway during oral breathing (P=0.001); The reduction of the distance between the mandible and the posterior pharyngeal wall was positively correlated with the length of the airway (P<0.001). Conclusion:Mouth breathing leads to the shortening of the long axis of the tongue, the reduction of the contact area between the soft palate and the tongue, vertical distance between the mandible and the posterior pharyngeal wall, and the cross-sectional area of the epiglottis plane. These changes vary between OSAHS patients and controls. During mouth breathing, the diameters, areas and volumes of the RP area decreased, and were more significant in severe cases.

目的:比较阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者和健康人在口腔或鼻腔呼吸过程中咽部形态的变化,探讨相关影响因素。方法:29名OSAHS成年患者和20名非打鼾对照者在受试者清醒时和用鼻夹进行口呼吸时接受了MRI,以获得上呼吸道结构测量。分析如下:①观察非打鼾控制型OSAHS患者口腔和鼻腔呼吸上气道结构的变化;②比较OSAHS患者与对照组在呼吸过程中上气道结构变化的差异及其影响因素。结果:对照组包括15名男性和5名女性,呼吸暂停低通气指数(AHI)PPP>0.05,但OSAHS患者RP气道最小截面积和体积减小(PP=0.017),患者的AHI与口腔呼吸时RP气道体积减小呈正相关(P=0.001);下颌骨与咽后壁之间距离的缩短与气道长度呈正相关(结论:口腔呼吸导致舌头长轴缩短,软腭与舌头的接触面积减小,下颌骨与咽后壁的垂直距离减小,会厌平面的横截面积减小。OSAHS患者和对照组的这些变化各不相同RP区的es降低,在重症病例中更为显著。
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Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
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