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Synergic fabrication of arsenic and anticancer drug-loaded ZIF-8 nanocomposites for improved radiofrequency ablation of liver metastasis cancer therapy 协同制备砷和抗癌药物负载的ZIF-8纳米复合材料用于肝转移癌的射频消融治疗
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-26 DOI: 10.1080/10667857.2023.2243582
Dongwen Rong, Junmei Jia, Haile Qiu, Yanyan Liu, Chenan Liu, Xiaoyuan Wei
ABSTRACT Clinical treatment of hepatocellular carcinoma (HCC) is notoriously tricky because radiofrequency ablation (RFA) might encourage metastasis of remaining HCC. . The therapeutic efficacy of arsenic (A) and promising anticancer drug gemcitabine (G)-loaded zeolitic imidazolate framework-8 nanocomposites (AG@ZIF-8 NCs) on tumour remnants wasinvestigated. Results demonstrated that RFA significantly increased proliferation, induced metastasis, and triggered angiogenesis in recurrent tumours. We show that significant angiogenesis following RFA can increase the enhanced permeability and retention (EPR) effects and emphasize ZIF-8 carriers in recurrent tumours. e effectively fabricated biocompatible AG@ZIF-8 NCs. And they were superior to free gemcitabine in inhibiting cell proliferations, inducing apoptosis, blocking cell invasion and migration, and reversing in vitro EMT following sublethal heat treatment. In addition, AG@ZIF-8 NCs showed significantly improved therapeutic efficiency by reducing residual tumour development and in vivo metastasis compared to free gemcitabine. This study establishes a new standard for managing HCC that persists after RFA.
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引用次数: 0
In-service property prediction of X80 self-shielded flux-cored (FCAW) girth weld metal based on strain ageing kinetics 基于应变时效动力学的X80自屏蔽药芯环焊缝在役性能预测
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-26 DOI: 10.1080/10667857.2023.2271305
Yuran Fan, Jian Shuai, Xin Su, Yalei Wang, Xiaojie Li, Yuntao Li, Xueda Li
ABSTRACT In order to achieve in-service safety evaluation of girth weld, property prediction of X80 self-shielded flux-cored girth weld metal based on strain ageing kinetics was conducted. Strength increment (ΔY) and toughness reduction (ΔCVN) relationship was obtained through tensile and Charpy impact test using specimens before and after strain ageing. 1% prestrain was conducted and then aged at different conditions (150°C/100°C for 1–6 h, 80°C/50°C for 1–120 days). Strain ageing kinetics was investigated based on experiment results, and diffusion activation energy (Q) was calculated as 88.1 kJ/mol. The correlation equation of ageing temperature and period was obtained: , T 1
{"title":"In-service property prediction of X80 self-shielded flux-cored (FCAW) girth weld metal based on strain ageing kinetics","authors":"Yuran Fan, Jian Shuai, Xin Su, Yalei Wang, Xiaojie Li, Yuntao Li, Xueda Li","doi":"10.1080/10667857.2023.2271305","DOIUrl":"https://doi.org/10.1080/10667857.2023.2271305","url":null,"abstract":"ABSTRACT In order to achieve in-service safety evaluation of girth weld, property prediction of X80 self-shielded flux-cored girth weld metal based on strain ageing kinetics was conducted. Strength increment (ΔY) and toughness reduction (ΔCVN) relationship was obtained through tensile and Charpy impact test using specimens before and after strain ageing. 1% prestrain was conducted and then aged at different conditions (150°C/100°C for 1–6 h, 80°C/50°C for 1–120 days). Strain ageing kinetics was investigated based on experiment results, and diffusion activation energy (Q) was calculated as 88.1 kJ/mol. The correlation equation of ageing temperature and period was obtained: , T 1<T 2 <423 K. It is predicted that, since occurrence of 1% prestrain, toughness of girth weld metal would drop down to <80 J after 3.9 years service in the present case, and its service safety should be reconsidered. Other prediction should be based on experimental results of specific consumable and welding parameters.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"6 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134909486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green synthesis of biofabricated silver nanoparticles from Syzygium aromaticum seeds: spectral characterization and evaluation of its anti-mycobacterial activity, cytotoxicity assessment on zebrafish embryo and Artemia salina 绿色合成香薷种子生物合成纳米银:光谱表征、抗分枝杆菌活性评价、斑马鱼胚胎和盐蒿细胞毒性评价
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-23 DOI: 10.1080/10667857.2023.2269358
Mettilda Dhanislas, Shobana Sampath, Mary Shamya, Jerrine Joseph, Madhavan Yasasve, Mohammad Z. Ahmed, Ali S. Alqahtani, Shadab Kazmi, Perumal Asaithambi, Arumugam Suresh
The lack of a viable vaccine and the emergence of novel Mycobacterium tuberculosis (MTB) strains that are particularly resistant to treatments, presage a complicated future situation. Biosynthesized nanomaterials are currently proving to be a viable antibacterial therapeutic option, including for MTB infection treatment. The goal of this work is to synthesize silver nanoparticles (AgNPs) from Syzygium aromaticum seeds and investigate their antimicrobial, anti-tubercular, and cytotoxic properties using zebrafish embryos and Artemia salina. The UV spectrophotometer, SEM-EDAX, TEM and FTIR measurements were used to characterize the AgNPs. Antibacterial activity was performed against S. aureus, P. aeruginosa, E. coli and K. pneumoniae and exhibited potential inhibitory activity towards the bacterial cultures. The MABA assay was used to investigate the anti-mycobacterial activity, and the AgNPs showed the highest percentage of inhibition in both test concentrations (250 and 500 µg/ml).
缺乏可行的疫苗以及对治疗特别具有耐药性的新型结核分枝杆菌(MTB)菌株的出现预示着未来的复杂情况。生物合成纳米材料目前被证明是一种可行的抗菌治疗选择,包括结核分枝杆菌感染的治疗。本研究的目的是利用斑马鱼胚胎和盐蒿(Artemia salina)合成银纳米颗粒(AgNPs),并研究其抗菌、抗结核和细胞毒性。采用紫外分光光度计、SEM-EDAX、TEM和FTIR对AgNPs进行了表征。对金黄色葡萄球菌、铜绿假单胞菌、大肠杆菌和肺炎克雷伯菌均有抑菌活性,并对细菌培养物表现出潜在的抑制活性。用MABA检测抗分枝杆菌活性,结果表明,AgNPs在250µg/ml和500µg/ml两种浓度下的抑制率最高。
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引用次数: 0
Microstructure evolution and creep-rupture behaviour of a low-cost Fe-Ni-based superalloy 一种低成本铁镍基高温合金的显微组织演变及蠕变断裂行为
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-23 DOI: 10.1080/10667857.2023.2270865
L.L. Wei, B.K. Pan, Y.G. Wang, B. Li, X.S. Jia
The pursuit of low-cost superalloys with excellent creep property is of great importance for practical engineering application. In this study, the creep performance, microstructure evolution and deformation mechanism of a low-cost Fe-Ni-based superalloy under the condition of 750°C/130 MPa and 700°C/200 MPa were investigated. The creep rupture life reached 14,715 h and 12,716 h, respectively, under the aforementioned conditions. After long-term creep, carbides and γ′ particles (Ni3(Al,Ti)) with spherical shape grew gradually due to the Ostwald ripening. Abnormal coarse needle-like γ′ phase presented at grain boundaries and grew along preferred orientation under the synergy effect of grain boundary migration, stress, and diffusion. Influence of precipitate-free zones, carbides, and coincidence site lattice (CSL) boundary on the creep properties were discussed. The creep deformation mechanism of the Fe-Ni-based superalloy were dominated by dislocations slip. Dislocations moved via by-passing the γ′ phase and formed dislocation bows around the precipitates.
追求具有优异蠕变性能的低成本高温合金对实际工程应用具有重要意义。研究了一种低成本铁镍基高温合金在750℃/130 MPa和700℃/200 MPa条件下的蠕变性能、微观组织演变及变形机理。在上述条件下,蠕变断裂寿命分别达到14,715 h和12,716 h。长期蠕变后,球状碳化物和γ′粒子(Ni3(Al,Ti))因奥斯特瓦尔德成熟而逐渐长大。在晶界迁移、应力和扩散的协同作用下,晶界处出现异常的粗针状γ′相,并沿择优取向生长。讨论了无析出区、碳化物和重合点阵边界对蠕变性能的影响。fe - ni基高温合金的蠕变机制以位错滑移为主。位错绕过γ′相移动,在析出相周围形成位错弓。
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引用次数: 0
A flexible triboelectric sensor based on P(VDF-co-HFP)/MXene for breath and posture monitoring in basketball motion 一种基于P(VDF-co-HFP)/MXene的柔性摩擦电传感器,用于篮球运动中的呼吸和姿势监测
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-17 DOI: 10.1080/10667857.2023.2262131
Yang Li, Dongyuan Xu
Recently, sports monitoring sensors based on flexible wearable technology have attracted much attention. Here, we reported a P(VDF-co-HFP)/MXene-based triboelectric nanogenerator (PM-TENG) to harvest bio-mechanical energy. The introduction of MXene can significantly improve the dielectric constant of P(VDF-co-HFP), thereby achieving higher electron harvesting ability. The PM-TENG can obtain the maximum instantaneous power of 1.68 mW contacted with a resistance of 4 MΩ. Furthermore, the PM-TENG can be also integrated inside the mask to monitor changes in respiratory status before and after basketball exercise. Meanwhile, the PM-TENG installed inside the shoes can be used to distinguish different gaits in basketball, which will be used to assist in basketball training. This flexible sport sensor demonstrates potential application value in basketball training assistance.
近年来,基于柔性可穿戴技术的运动监测传感器备受关注。在这里,我们报道了一种基于P(VDF-co-HFP)/ mxeni的摩擦电纳米发电机(PM-TENG)来收集生物机械能。MXene的引入可以显著提高P(VDF-co-HFP)的介电常数,从而获得更高的电子捕获能力。PM-TENG在接触电阻4 MΩ时可获得1.68 mW的最大瞬时功率。此外,PM-TENG还可以集成在口罩内,监测篮球运动前后呼吸状态的变化。同时,安装在球鞋内的PM-TENG可用于区分篮球运动中的不同步态,辅助篮球训练。该柔性运动传感器在篮球辅助训练中具有潜在的应用价值。
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引用次数: 0
Arrhenius constitutive equation and artificial neural network model of flow stress in hot deformation of offshore steel with high strength and toughness 海洋高强韧钢热变形流变应力的Arrhenius本构方程和人工神经网络模型
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-16 DOI: 10.1080/10667857.2023.2264670
Li Fangpo, Li Ning, Ren Xiaojian, Qiao Song, Lu Caihong, Wang Jianjun, Xu Yang, Wang Bin
In this study, the thermal deformation behaviour of a high strength offshore steel at different temperatures and rates was investigated through thermal compression experiments.An Arrhenius constitutive model and a back propagation artificial neural network (BP-ANN) were established to address more complex deformation characteristics. The performances of both models were was evaluated using standard statistical parameters such as the correlation coefficient (R) and average absolute relative error (AARE). The results showed that both models can accurately predict the rheological stresses generated during deformation.The BP-ANN outperforms the Arrhenius equation model with correlation coefficients of fit greater than 99.9% and less than 0.8% relative error. At a strain rate of 0.01 s−1 and 10 s−1, the accuracy of the ANN decreases slightly due to the fact that it exceeds the strain rate range of the training set, as compared to the Arrhenius constitutive equations as these are more accurately predicted.
在本研究中,通过热压缩实验研究了一种高强度近海钢在不同温度和速率下的热变形行为。针对更为复杂的变形特征,建立了Arrhenius本构模型和BP-ANN反传播人工神经网络(BP-ANN)。采用相关系数(R)和平均绝对相对误差(AARE)等标准统计参数对两种模型的性能进行评价。结果表明,两种模型均能准确预测变形过程中产生的流变应力。BP-ANN的拟合相关系数大于99.9%,相对误差小于0.8%,优于Arrhenius方程模型。在应变速率为0.01 s−1和10 s−1时,与Arrhenius本构方程相比,人工神经网络的准确性略有下降,因为它超出了训练集的应变速率范围,因为这些预测更准确。
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引用次数: 0
The triboelectric sensor based on PDMS/SGO for human running posture and physical fitness health monitoring 基于PDMS/SGO的摩擦电传感器用于人体跑步姿势和体质健康监测
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-10-16 DOI: 10.1080/10667857.2023.2254613
Shuai Zhang, Hailin Yang, Jianghua Li
Recently, research about the intelligent sports equipment based on triboelectric sensor for athlete posture monitoring has made progress. However, the exploration of new triboelectric materials remains an important challenge to be faced. Hence, we ingeniously design a polydimethylsiloxane (PDMS)/silanized graphite oxide (SGO)-based triboelectric nanogenerator (PS-TENG) for running posture and physical health monitoring. The introduction of SGO has improved the electron capture capability of PDMS, thereby achieving high output of PS-TENG. From the results, under an 60 MΩ resistance, the power density of PS-TENG reaches a peak of 1780 mW·m−2. Furthermore, athletes undergo various postures during the running process, so monitoring special postures is very meaningful, such as jogging, long jump, walking, etc. Especially, according to the self-charging mechanism, PS-TENG can indirectly evaluate physical energy analysis during running by storing electrical energy in capacitors. This triboelectric sensor can assist in posture monitoring and physical fitness monitoring during running.
近年来,基于摩擦电传感器的运动员姿态监测智能运动装备的研究取得了一定的进展。然而,探索新的摩擦电材料仍然是一个重要的挑战。因此,我们巧妙地设计了一种基于聚二甲基硅氧烷(PDMS)/硅化氧化石墨(SGO)的摩擦电纳米发电机(PS-TENG),用于跑步姿势和身体健康监测。SGO的引入提高了PDMS的电子捕获能力,从而实现了PS-TENG的高输出。结果表明,在60 MΩ电阻下,PS-TENG的功率密度峰值为1780 mW·m−2。此外,运动员在跑步过程中会经历各种姿势,因此对特殊姿势进行监测是非常有意义的,如慢跑、跳远、步行等。特别是,根据自充电机制,PS-TENG可以通过在电容器中存储电能来间接评估运行过程中的物理能量分析。这种摩擦电传感器可以在跑步过程中辅助姿势监测和身体健康监测。
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引用次数: 0
Ionic liquid addition to the MAPb0.5Sn0.5I3 perovskites: the properties and optoelectronic performance analysis using DFT calculations 离子液体加入MAPb0.5Sn0.5I3钙钛矿:用DFT计算分析其性质和光电子性能
4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-09-12 DOI: 10.1080/10667857.2023.2254137
Manala Tabu Mbumba, Mina Guli, Muhammad Waleed Akram, Yujing Zhang, Yifan Yang
ABSTRACT The characteristics and performance of perovskites are adversely impacted by the presence of a Sn metal at high-temperature conditions. In this study, CASTEP analysis and density functional theory are used to examine the impact of 1-butyl-3-methylimidazolium bromine ionic liquid in enhancing the features of Pb-Sn halide perovskite alloys. According to the study’s findings, the ionic liquid device has better electronic, optical, mechanical, and thermodynamic properties than the control sample because it can anchor the MA cation through hydrogen bonding and can reduce the grain boundaries of the perovskite film, making it tolerable up to high temperatures above 80°C. In comparison to the control device, the ionic liquid perovskites’ photovoltaic characteristics were also improved. This research lays the way for the development of Pb-Sn alloys with enhanced characteristics that are likely to result in the development of stable and effective lead-free perovskite solar cells.
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引用次数: 1
Significant impact of co-doping Eu-doped ZnO nanoparticles with Li on structural–optical properties relationship 铕掺杂ZnO纳米粒子与Li共掺杂对结构-光学性质关系的显著影响
IF 3.1 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-09-03 DOI: 10.1080/10667857.2023.2253646
Ashok Kumawat, S. Chattopadhyay, K. Misra
ABSTRACT We describe here the structural evolution and optical properties of co-doping of Eu-doped ZnO nanoparticles with lithium synthesized by the sol-gel process. The characterization was carried out via X-ray diffraction (XRD), Fourier transmission infrared (FTIR), UV-Vis spectroscopy, and photoluminescence (PL) techniques. XRD confirmed hexagonal wurtzite phase of ZnO nanoparticles with crystallite size in the range of 22–61 nm. The band gap calculated from UV-vis spectra was in the range of 3.30–3.26 eV for undoped and Li and Eu co-doped ZnO nanoparticles, respectively, while photoluminescence study indicated that Li in Eu-ZnO affected the PL emission intensity, which was attributed to defects present in the crystal lattice. The field emission scanning electron microscopy (FESEM) images revealed the diverse morphology containing, spherical, tri-, tetra-, penta- and hexagonal rod-like nanostructures.
{"title":"Significant impact of co-doping Eu-doped ZnO nanoparticles with Li on structural–optical properties relationship","authors":"Ashok Kumawat, S. Chattopadhyay, K. Misra","doi":"10.1080/10667857.2023.2253646","DOIUrl":"https://doi.org/10.1080/10667857.2023.2253646","url":null,"abstract":"ABSTRACT We describe here the structural evolution and optical properties of co-doping of Eu-doped ZnO nanoparticles with lithium synthesized by the sol-gel process. The characterization was carried out via X-ray diffraction (XRD), Fourier transmission infrared (FTIR), UV-Vis spectroscopy, and photoluminescence (PL) techniques. XRD confirmed hexagonal wurtzite phase of ZnO nanoparticles with crystallite size in the range of 22–61 nm. The band gap calculated from UV-vis spectra was in the range of 3.30–3.26 eV for undoped and Li and Eu co-doped ZnO nanoparticles, respectively, while photoluminescence study indicated that Li in Eu-ZnO affected the PL emission intensity, which was attributed to defects present in the crystal lattice. The field emission scanning electron microscopy (FESEM) images revealed the diverse morphology containing, spherical, tri-, tetra-, penta- and hexagonal rod-like nanostructures.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"49 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82728572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Current advancements in the development of bionic organs using regenerative medicine and 3D tissue engineering 利用再生医学和三维组织工程发展仿生器官的最新进展
IF 3.1 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2023-08-29 DOI: 10.1080/10667857.2023.2242732
D. K. Shanmugam, S. C. Anitha, Vedhapriya Souresh, Yasasve Madhavan, Shobana Sampath, Divyambika Catakapatri Venugopal, M. Saravanan
ABSTRACT Bio-artificial organs, commonly referred to as bionic organs, are artificial structures that perform the same functions as natural organs. In regenerative medicine, damaged organs are repaired using biological components including growth factors and stem cells. The advancement of tissue engineering, which aims to harness the inherent regenerative potential of human body organs to rebuild normal biological function, has benefited greatly from the use of biomaterials. The rapidly expanding field of regenerative medicine has brought the usage of biomaterials and their functions in the production of new tissue. Organs-on-chips are seen as a concept performer in tissue engineering with significant potential for future ‘clinical trials on a chip’ and a step towards developing customized medicine. With the advancement of 3D printing technology, the manufacturing constraints of biomedical devices have been solved using cutting-edge biomimetic structures. This review covers the areas on bionic organs such as organ on a chip with tissue engineering, bio grafting, 3D bio-printing and the stem cell techniques that are employed in regenerative medicine.
{"title":"Current advancements in the development of bionic organs using regenerative medicine and 3D tissue engineering","authors":"D. K. Shanmugam, S. C. Anitha, Vedhapriya Souresh, Yasasve Madhavan, Shobana Sampath, Divyambika Catakapatri Venugopal, M. Saravanan","doi":"10.1080/10667857.2023.2242732","DOIUrl":"https://doi.org/10.1080/10667857.2023.2242732","url":null,"abstract":"ABSTRACT Bio-artificial organs, commonly referred to as bionic organs, are artificial structures that perform the same functions as natural organs. In regenerative medicine, damaged organs are repaired using biological components including growth factors and stem cells. The advancement of tissue engineering, which aims to harness the inherent regenerative potential of human body organs to rebuild normal biological function, has benefited greatly from the use of biomaterials. The rapidly expanding field of regenerative medicine has brought the usage of biomaterials and their functions in the production of new tissue. Organs-on-chips are seen as a concept performer in tissue engineering with significant potential for future ‘clinical trials on a chip’ and a step towards developing customized medicine. With the advancement of 3D printing technology, the manufacturing constraints of biomedical devices have been solved using cutting-edge biomimetic structures. This review covers the areas on bionic organs such as organ on a chip with tissue engineering, bio grafting, 3D bio-printing and the stem cell techniques that are employed in regenerative medicine.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"20 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79219531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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Materials Technology
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