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Prevalence and clinical potential of extraspinal incidental findings in lumbosacral spine MRI of patients with suspected disc diseases 疑似椎间盘疾病患者腰骶椎MRI椎外偶发表现的患病率及临床潜力
IF 0.5 Q3 Medicine Pub Date : 2021-12-23 DOI: 10.13181/mji.oa.215550
S. Rashid
BACKGROUND Incidental findings could be observed in organs close to the spine while reporting lumbosacral spine magnetic resonance imaging (MRI). This study aimed to report the prevalence and clinical potential of extraspinal incidental findings in lumbosacral MRI of patients with suspected disc diseases. METHODS This single-centered cross-sectional study was carried out on 420 consecutive adult patients who underwent lumbar spine MRI for suspected disc disease from January to July 2019. The MRI was checked for the presence of extraspinal incidental findings, and each finding was categorized according to the body organ and its clinical significance. Each MRI plane that best displayed the findings was recorded, and the association between the findings and patient's age and sex was determined. RESULTS Of 420 samples, 135 cases showed extraspinal findings (32.1%), and 7.6% of the patients displayed suspicious lesions. The urinary tract was the most common system (18.6%) to display both clinically significant (5.0%) and benign findings (13.6%), and the axial MRI section was the plane which showed most of the incidental findings. Incidental findings in any body system were rarely found in the younger patients. Females had significantly higher benign findings than males (p = 0.002). CONCLUSIONS The prevalence of extraspinal findings in lumbosacral spine MRI is high, and some are significant. Most findings are related to the urinary tract and best displayed in the axial plane.
背景在报告腰骶部脊柱磁共振成像(MRI)时,可以在靠近脊柱的器官中观察到偶然的发现。本研究旨在报告疑似椎间盘疾病患者腰骶部MRI中脊髓外偶然发现的患病率和临床潜力。方法对2019年1月至7月连续420名因疑似椎间盘疾病接受腰椎MRI检查的成年患者进行单中心横断面研究。检查MRI是否存在脊髓外偶然发现,并根据身体器官及其临床意义对每个发现进行分类。记录每个最能显示结果的MRI平面,并确定结果与患者年龄和性别之间的关联。结果在420例标本中,135例(32.1%)出现脊髓外病变,7.6%的患者出现可疑病变。尿路是最常见的系统(18.6%),同时显示出临床意义(5.0%)和良性表现(13.6%),轴向MRI切片是显示大多数偶然发现的平面。任何身体系统中的偶然发现在年轻患者中都很少发现。女性的良性表现明显高于男性(p=0.002)。结论腰骶椎MRI中脊外表现的发生率很高,有些表现很显著。大多数发现与尿路有关,最好在轴向平面上显示。
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引用次数: 0
Efficacy of video-based psychotherapy in reducing psychological distress of COVID-19 patients treated in isolation ward 视频心理治疗减轻隔离病房新冠肺炎患者心理压力的效果
IF 0.5 Q3 Medicine Pub Date : 2021-12-07 DOI: 10.13181/mji.oa.215473
P. R. Lukman, A. Saputra, S. D. Elvira, Heriani, Alfi Fajar Almasyhur, Leonita Ariesti Putri, C. Alfonso, Reina Rahma Noviasari
BACKGROUND Hospitalized patients with COVID-19 experience isolation during treatment, which may cause psychological distress. Thus, alternative ways to deliver psychological support are needed when face-to-face therapy is not possible. This study aimed to investigate the efficacy of video-based psychotherapy in reducing distress in COVID-19 patients treated in an isolation ward. METHODS This quasi-experimental trial without a control group included 42 COVID-19 patients aged 20–59 years. Participants were recruited conveniently in the COVID-19 isolation ward in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. They watched three brief psychotherapy videos including relaxation, managing thoughts and emotions, and mindfulness for approximately 30 min. The videos were created by the Department of Psychiatry, Faculty of Medicine, Universitas Indonesia. Subjective units of distress scale (SUDS) was measured before and after watching all videos. Data were analyzed using the Wilcoxon-signed rank test. RESULTS All 42 subjects finished watching the videos. 31 subjects experienced a significant median decrease in SUDS score after the intervention. The effect size of the psychotherapy videos for the SUDS score was 0.485 (95% CI 0.302 to 0.634). CONCLUSIONS Watching psychotherapy videos is effective in reducing the SUDS score for COVID-19 patients in an isolation ward. Our brief video-based psychotherapy intervention has reduced psychological distress in hospitalized COVID-19 patients with limited access to face-to-face consultations due to the risk of disease transmission.
背景新冠肺炎住院患者在治疗过程中会出现隔离,这可能会导致心理困扰。因此,当无法进行面对面的治疗时,需要提供心理支持的替代方法。本研究旨在调查在隔离病房接受治疗的新冠肺炎患者中,基于视频的心理治疗在减轻痛苦方面的效果。方法这项没有对照组的准实验试验包括42名年龄在20-59岁之间的新冠肺炎患者。参与者被方便地招募到印度尼西亚雅加达Cipto Mangunkusumo医院的新冠肺炎隔离病房。他们观看了三个简短的心理治疗视频,包括放松、管理思想和情绪以及正念,持续了大约30分钟。这些视频由印尼大学医学院精神病学系制作。在观看所有视频之前和之后测量主观痛苦量表(SUDS)。使用Wilcoxon符号秩检验对数据进行分析。结果42名受试者均完成了视频观看。31名受试者在干预后SUDS评分中位显著下降。心理治疗视频对SUDS评分的影响大小为0.485(95%CI 0.302至0.634)。结论在隔离病房观看心理治疗视频可有效降低新冠肺炎患者的SUDS评分。我们短暂的基于视频的心理治疗干预减少了新冠肺炎住院患者的心理痛苦,这些患者由于疾病传播风险而无法获得面对面的咨询。
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引用次数: 2
Incidence and characteristics of de novo stress urinary incontinence after pelvic organ prolapse vaginal repair 盆腔器官脱垂阴道修复术后新发应激性尿失禁的发生率及特点
IF 0.5 Q3 Medicine Pub Date : 2021-11-23 DOI: 10.13181/mji.oa.204163
Suskhan Djusad, Ihya Ridlo Nizomy, S. Hakim, Tyas Priyatini, F. Moegni, A. Meutia, B. Santoso
BACKGROUND Some patients who undergo pelvic floor reconstruction for pelvic organ prolapse (POP) may experience a de novo stress urinary incontinence (SUI) postoperatively. We aimed to investigate the incidence and characteristics of de novo SUI in patients who underwent pelvic floor reconstruction at the national referral hospital in Indonesia. METHODS This cross-sectional study evaluated 108 patients who underwent pelvic floor reconstruction due to POP between January 2016 and December 2017. Per the inclusion criteria, 75 women were enrolled using a consecutive sampling. The incidence of de novo SUI was determined 6–12 months postoperatively using the Indonesian version of the questionnaire for urinary incontinence diagnosis and objectively using the cough stress test during gynecologic examination after a negative preoperative prolapse reduction stress test. RESULTS The average age, parity, body mass index, and years since menopause onset were 56.17 (4.67) years, 3.17 (1.07), 28.58 (5.18) kg/m2, and 12.8 (7.0) years, respectively. De novo SUI was seen in 8.0% (6 of 75) patients at 6–7 months postoperatively, with 3 (50.0%) had severe POP and 3 (50.0%) had a mild POP. Most of these patients (4 of 6, 66.7%) had undergone procedures other than colpocleisis for POP reconstruction. CONCLUSIONS The incidence of de novo SUI after gynecologic surgery for POP at a national referral hospital in Indonesia is 8%. Most patients were aged <60 years, had a parity of <4, were nonobese, were menopausal, and had diabetes.
背景:一些因盆腔器官脱垂(POP)而接受盆底重建术的患者可能会在术后重新出现应激性尿失禁(SUI)。我们的目的是调查在印度尼西亚国家转诊医院接受盆底重建的患者中新生SUI的发生率和特征。方法:本横断面研究评估了2016年1月至2017年12月期间因POP接受盆底重建的108例患者。根据纳入标准,采用连续抽样方法纳入75名妇女。术后6-12个月采用印尼语版尿失禁诊断问卷,并在术前脱垂减压试验阴性的妇科检查中客观使用咳嗽应激试验来确定新生SUI的发生率。结果平均年龄56.17(4.67)岁,胎次3.17(1.07)岁,体重指数28.58 (5.18)kg/m2,绝经年数12.8(7.0)岁。8.0%(75例中有6例)的患者在术后6 - 7个月出现了新生SUI,其中3例(50.0%)为重度POP, 3例(50.0%)为轻度POP。大多数患者(4 / 6,66.7%)接受了阴道切开以外的手术进行POP重建。结论:印度尼西亚一家国家转诊医院的POP妇科手术后新发SUI发生率为8%。大多数患者年龄<60岁,胎次<4,非肥胖,绝经,患有糖尿病。
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引用次数: 2
Evaluating laboratory screening tests for malaria on blood donors candidates to reduce the risk of transfusion-transmitted malaria in an endemic area of Indonesia 评估对献血者候选人进行的疟疾实验室筛查试验,以减少印度尼西亚一个流行地区输血传播疟疾的风险
IF 0.5 Q3 Medicine Pub Date : 2021-10-10 DOI: 10.13181/mji.oa.215491
Nethasia Louhenapessy, Ria Syafitri Evi Gantini, Susan Rahayu, Elisabeth Lilipory, Heri Wibowo, Yuyun Soedarmono, Inge Sutanto
BACKGROUND Laboratory screening of blood donors for malaria has not been routinely performed in Indonesia. Current policy and practice simply exclude donors based on a history of active clinical malaria. This study was aimed to evaluate laboratory screening tests for malaria among blood donors in an endemic area of Indonesia. METHODS The study was conducted on 550 consecutive blood samples withdrawn from volunteer donors at the Red Cross Blood Transfusion Unit in Ambon city using microscopic and rapid diagnostic tests for antigen as well as for antibody. Furthermore, 248 of those 550 samples were also tested for the presence of malaria DNA using 18S rRNA marker. Statistical analysis was done descriptively using SPSS software version 15 (SPSS Inc., USA). RESULTS The overall malaria positivity rate among the donors was 4.5% (25/550). None of the specimens tested using microscopy or rapid test for malaria antigen assay were positive. However 22 (4.0%) samples were positive for malaria antibody against Plasmodium falciparum; while 3 (1.2%) were positive by PCR. CONCLUSIONS Laboratory testing for blood donors may be used to prevent transfusiontransmitted malaria in an endemic area of Indonesia.
背景:在印度尼西亚,对献血者进行疟疾实验室筛查尚未成为常规做法。目前的政策和做法只是简单地根据临床疟疾活跃史排除捐助者。本研究的目的是评价印度尼西亚一个疟疾流行地区献血者的疟疾实验室筛查试验。方法对安汶市红十字会输血中心志愿献血者的550份连续血液样本进行研究,采用抗原和抗体的显微镜和快速诊断检测。此外,还使用18S rRNA标记对这550个样本中的248个样本进行了疟疾DNA检测。统计分析使用SPSS软件版本15 (SPSS Inc., USA)进行描述性分析。结果供体疟疾总阳性率为4.5%(25/550)。使用显微镜或疟疾抗原测定快速试验检测的标本均未呈阳性。恶性疟原虫疟疾抗体阳性22份(4.0%);PCR阳性3例(1.2%)。结论对献血者的实验室检测可用于预防印度尼西亚某流行地区的输血传播性疟疾。
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引用次数: 0
Reliability and validity of the Indonesian version of the aging males’ symptoms 印尼版老年男性症状的信度和效度
IF 0.5 Q3 Medicine Pub Date : 2021-10-07 DOI: 10.13181/mji.oa.215314
Dyandra Parikesit, Miftah Adityagama, Widi Atmoko, P. Birowo, Akmal Taher, Nur Rasyid
BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability.
背景老年男性症状(AMS)量表旨在研究老年男性的问题,特别是与生活质量有关的问题。目前,没有有效和可靠的印尼版AMS量表。本研究旨在翻译并评估印尼语版AMS量表的效度和信度。方法采用横断面研究方法,将现有的AMS量表翻译成印尼语,于2020年5月至8月在40岁男性中进行测试。AMS量表的跨文化验证由两名独立认证的翻译人员将问卷从英语翻译成印尼语。印尼版AMS量表的效度通过进行Pearson相关(r)分析来测量。以2周为间隔,对118名被试进行了信度测试和重测。此外,测量Cronbach’s alpha值作为参考。第一次检测是在东雅加达Matraman的一次集体献血活动中进行的,第二次检测是在Cipto Mangunkusumo医院进行的。结果印尼语版AMS量表有效,具有良好的内部一致性,Cronbach α值为0.74。重测信度较好,r值为0.981。Pearson相关检验显示,问卷各题均有效(p<0.05),且呈正相关。结论本研究编制的印尼语版AMS量表有效,信度良好。
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引用次数: 0
Precision health care strategies for older adults with diabetes in Indonesia: a Delphi consensus study 印尼老年糖尿病患者的精准医疗保健策略:德尔菲共识研究
IF 0.5 Q3 Medicine Pub Date : 2021-10-07 DOI: 10.13181/mji.oa.215525
Satriya Pranata, Shu-Fang Vivienne Wu, Chun-Hua Chu, Khristophorus Heri Nugroho
BACKGROUND Studies on precision health care for older adults with diabetes in Indonesia are still limited. This study was aimed to reach the experts consensus on the suitable precision health care strategies for older adults with diabetes. METHODS A total of 10 experts (4 physicians, 4 nurses, and 2 dietitians) agreed to participate in the 3-round interview using Delphi technique. The experts should have at least 5 years of experience in teaching or working as health professionals in a hospital. RESULTS Consensus was reached that precision health care consisted of eight elements: self-management, interdisciplinary collaborative practice, personalized genetic or lifestyle factors, glycemic target, patient preferences, glycemic control, patient priority-directed care, and biodata- or evidence-based practice. The strategies of precision health care for diabetes were divided into seven steps: conducting brief deducting teaching; assessing self-management level and risk of cardiovascular disease; organizing a brainstorming session among patients to exchange experiences on glycemic target and specific target behavior; making a list of patients’ needs and ranking the priorities; setting a goal and writing action; doing follow-up; and reporting the goal attempts. CONCLUSIONS The eight elements of precision health care provided the basis of precision health care strategies for diabetic older adults, which are the real and measurable strategies for precision health care implementation in clinical settings.
背景印度尼西亚对老年糖尿病患者精准医疗的研究仍然有限。这项研究旨在就老年糖尿病患者的适当精准医疗策略达成专家共识。方法共有10名专家(4名医生、4名护士和2名营养师)同意使用德尔菲技术进行三轮访谈。专家应具有至少5年的医院卫生专业教学或工作经验。结果一致认为,精准医疗由八个要素组成:自我管理、跨学科合作实践、个性化遗传或生活方式因素、血糖目标、患者偏好、血糖控制、患者优先指导护理以及生物数据或循证实践。糖尿病精准医疗策略分为七个步骤:进行简式演绎教学;评估自我管理水平和心血管疾病风险;在患者之间组织头脑风暴会议,交流血糖目标和特定目标行为方面的经验;列出患者的需求清单,并对优先事项进行排序;设定目标并写出行动;跟进;以及报告进球尝试。结论精准医疗的八个要素为糖尿病老年人的精准医疗策略提供了基础,这是在临床环境中实施精准医疗的真实和可衡量的策略。
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引用次数: 6
The importance of evidence based education and policy in public health: lessons learned from a repeated pandemic 以证据为基础的教育和公共卫生政策的重要性:从一次又一次大流行中吸取的教训
IF 0.5 Q3 Medicine Pub Date : 2021-10-06 DOI: 10.13181/mji.ed.215821
Agus Rizal Ardy Hariandy Hamid, Grace Wangge
[No abstract available]
[没有摘要]
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引用次数: 1
Potential predictors of detrusor underactivity in a urology outpatient clinic: a 5-year single center experience study 泌尿科门诊逼尿肌活动不足的潜在预测因素:一项为期5年的单中心经验研究
IF 0.5 Q3 Medicine Pub Date : 2021-10-04 DOI: 10.13181/mji.oa.215102
Soefiannagoya Soedarman, Harrina Erlinati Rahardjo
BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU.
尿动力学诊断为逼尿肌活动不足(DU),由膀胱肌肉强度和持续时间共同引起,导致膀胱排空时间延长。侵入性尿动力学在许多临床环境中受到限制,应该在高危患者中有效地进行,以减少手术期间和手术后出现并发症的风险。因此,本研究旨在确定在有限的临床环境中DU的潜在预测因素。方法回顾性分析2015 - 2020年在Cipto Mangunkusumo医院泌尿外科接受尿动力学治疗的患者的病历。采用卡方和Mann-Whitney方法分析年龄、性别、膀胱容量、膀胱顺应性、膀胱出口梗阻、卒中史、糖尿病(DM)状态和神经系统异常,以研究DU的潜在预测因素。并计算各因素的比值比(OR)。进一步采用Logistic回归进行分析。结果本研究共纳入649例患者。男性(OR = 1.74, 95% CI = 1.28 ~ 2.38)和DM (OR = 2.06, 95% CI = 1.36 ~ 3.11)患者发生DU的风险较高,而膀胱出口梗阻(OR = 0.54, 95% CI = 0.39 ~ 0.76)是DU的保护因素。此外,多因素分析显示,DU的潜在预测因素为男性(OR= 1.903, 95% CI = 1.37 ~ 2.64)、DM (OR= 1.899, 95% CI = 1.22 ~ 2.95)和膀胱出口梗阻(OR= 0.32, 95% CI = 0.32 ~ 0.65)。结论:年龄、性别、膀胱出口梗阻、糖尿病病史可成为DU的预测因素。
{"title":"Potential predictors of detrusor underactivity in a urology outpatient clinic: a 5-year single center experience study","authors":"Soefiannagoya Soedarman, Harrina Erlinati Rahardjo","doi":"10.13181/mji.oa.215102","DOIUrl":"https://doi.org/10.13181/mji.oa.215102","url":null,"abstract":"BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. \u0000METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. \u0000RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). \u0000CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44245349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multi-hole spherical CT scan method to characterize large quantities of bones in rats 多孔球形CT扫描方法表征大鼠大量骨骼
IF 0.5 Q3 Medicine Pub Date : 2021-10-01 DOI: 10.13181/mji.oa.215452
Neng Nenden Mulyaningsih, Ariadne Lakshmidevi Juwono, Djarwani Soeharso Soejoko, Dewi Apri Astuti
BACKGROUND New therapeutic options are often explored in in vivo studies using animals like rats. Since rats are small, it is difficult to examine them in a computed tomography (CT) scan. This study aimed to introduce a multi-hole spherical model CT scan method as a new, fast, economical, and reliable method to characterize large quantities of rat bones at once in estimating the timing of osteoporosis in ovariectomized white rats. METHODS 50 female white rats (12 weeks old) were treated as the control group, and 40 rats of the same age were ovariectomized to establish the osteoporosis model. Sham rats were sacrificed at 13, 15, 17, 19, and 21 weeks old, while the ovariectomized rats were sacrificed at 15, 17, 19, and 21 weeks old. Afterward, tibia bones were removed, placed in the multi-hole spherical model, and characterized using a CT scan. Their characteristics were compared using a scanning electron microscope (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD). RESULTS The Hounsfield unit scores resulted from the multi-hole spherical model CT scan method of tibia bones of rats were consistent with the percentage of the osteocyte cavities, canalicular diameters, and crystal size. The multi-hole spherical model CT scan method could produce 50 times more data than the SEM, TEM, or XRD. CONCLUSIONS Multi-hole spherical model CT scan was considered good and reliable in assessing bone quality parameters in rat samples simultaneously.
背景在使用大鼠等动物的体内研究中,经常探索新的治疗方案。由于大鼠体型较小,很难在计算机断层扫描中对其进行检查。本研究旨在介绍一种多孔球形模型CT扫描方法,作为一种新的、快速、经济、可靠的方法来同时表征大量大鼠骨骼,以估计去卵巢大鼠骨质疏松症的发生时间。方法50只12周龄雌性大鼠作为对照组,40只同龄大鼠去卵巢建立骨质疏松模型。Sham大鼠在13、15、17、19和21周龄时处死,而去卵巢大鼠在15、17,19和21周龄时处死。之后,胫骨被移除,放置在多孔球形模型中,并使用CT扫描进行表征。使用扫描电子显微镜(SEM)、透射电子显微镜(TEM)和X射线衍射(XRD)对它们的特性进行了比较。结果大鼠胫骨多孔球形模型CT扫描方法得到的Hounsfield单位积分与骨细胞腔的百分比、小管直径和晶体大小一致。多孔球形模型CT扫描方法可以产生比SEM、TEM或XRD多50倍的数据。结论多孔球形模型CT扫描在同时评估大鼠骨质量参数方面被认为是良好和可靠的。
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引用次数: 0
A cross-sectional study on the telemedicine usage and glycemic status of diabetic patients during the COVID-19 pandemic 新冠肺炎大流行期间糖尿病患者远程医疗使用及血糖状况的横断面研究
IF 0.5 Q3 Medicine Pub Date : 2021-09-30 DOI: 10.13181/mji.oa.215558
Novi Sulistia Wati, Pokkate Wongsasuluk, P. Soewondo
BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic disrupts selfmanagement in diabetic patients in Indonesia. This study aimed to determine the telemedicine usage and factors contributing to glycemic control in type 2 diabetes mellitus (T2DM) patients during the pandemic. METHODS A cross-sectional study was conducted in T2DM patients aged 25–54 years. The questionnaire included general characteristics, diabetes conditions, consultation factors, and self-care management. Glycemic status was evaluated using glycated hemoglobin (HbA1c) levels, which was categorized into poor (HbA1c≥7%) and good glycemic control (HbA1c<7%). Data were analyzed using chi-square and binary logistic regression. RESULTS Of 264 patients, only 19.2% used telemedicine and 60.2% had poor glycemic control during the pandemic. Overweight or obesity (odds ratio [OR] = 5.740 [95% confidence interval [CI] = 2.554–12.899]; p<0.001), insulin injection (OR = 3.083 [95% CI = 1.238–7.677]; p = 0.016), and frequent fried food consumption (OR = 5.204 [95% CI = 1.631–16.606]; p = 0.005) were the factors contributing to poor glycemic control. The risk is lower if exercised regularly (OR = 0.036 [95% CI = 0.007–0.195]; p<0.001) and consulted with a doctor using telemedicine (OR = 0.193 [95% CI = 0.044–0.846]; p = 0.029) or in-person visits (OR = 0.065 [95% CI = 0.016–0.260]; p<0.001). CONCLUSIONS Glycemic control was not optimal during the COVID-19 pandemic. Therefore, keeping a healthy lifestyle and staying connected with a doctor are important to ensure optimal blood glucose control and reduce the risk of diabetesrelated complications.
背景2019冠状病毒病(COVID-19)大流行扰乱了印度尼西亚糖尿病患者的自我管理。本研究旨在确定大流行期间2型糖尿病(T2DM)患者的远程医疗使用情况和影响血糖控制的因素。方法对25-54岁的T2DM患者进行横断面研究。问卷内容包括一般特征、糖尿病情况、咨询因素和自我保健管理。使用糖化血红蛋白(HbA1c)水平评估血糖状态,分为血糖控制不良(HbA1c≥7%)和血糖控制良好(HbA1c<7%)。数据分析采用卡方和二元逻辑回归。结果264例患者中,只有19.2%的患者在疫情期间使用远程医疗,60.2%的患者血糖控制较差。超重或肥胖(优势比[or] = 5.740[95%可信区间[CI] = 2.554-12.899];p<0.001)、胰岛素注射(OR = 3.083 [95% CI = 1.238-7.677];p = 0.016),经常食用油炸食品(OR = 5.204 [95% CI = 1.631-16.606];P = 0.005)是导致血糖控制不良的因素。如果经常锻炼,风险更低(OR = 0.036 [95% CI = 0.007-0.195];p<0.001),使用远程医疗咨询医生(OR = 0.193 [95% CI = 0.044-0.846];p = 0.029)或亲自就诊(or = 0.065 [95% CI = 0.016-0.260];p < 0.001)。结论COVID-19大流行期间血糖控制并非最佳。因此,保持健康的生活方式并与医生保持联系对于确保最佳血糖控制和降低糖尿病相关并发症的风险非常重要。
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引用次数: 2
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Medical Journal of Indonesia
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