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Mental health problems and coping strategy among pulmonary resident physicians during the COVID-19 pandemic in a tertiary respiratory hospital in Indonesia: a serial cross-sectional study 2019冠状病毒病大流行期间印尼一家三级呼吸系统医院肺病住院医师的心理健康问题及应对策略:一项系列横断面研究
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-02 DOI: 10.13181/mji.oa.226263
S. Andarini, J. Zaini, Triya Damayanti, Tribowo Tuahta Ginting Sugihen, H. Faisal
BACKGROUND Pulmonary resident physicians are part of the frontline workers for COVID-19 in the hospital and might require a suitable coping strategy to manage stress. Here, we described their mental health status and coping strategy during the COVID-19 pandemic. METHODS A cohort study was done to evaluate stress, anxiety, depression, and coping strategies among pulmonary resident physicians in a tertiary referral hospital. Questionnaires were administered in 4 time points between August 2020 and June 2021. The DASS-21 questionnaire measured depression, anxiety, and stress, while Brief COPE instrument qualified the coping strategy. RESULTS The total respondents who filled the questionnaire in 4 time points in August 2020, October 2020, February 2021, and June 2021 were 60, 93, 96, and 94 resident physicians with mean stress levels of 4.3, 6.1, 5.4, and 6.3, respectively. Depression, stress, and anxiety were less frequent during the study period, mostly mild or moderate. However, moderate anxiety slightly increased in June 2021 when the pandemic reached its peak. Most of them (95.8%) had effective coping strategies related to religious beliefs. CONCLUSIONS Effective coping strategies might preserve the pulmonary resident physicians’ mental health during the pandemic. Furthermore, the sociodemographic and cultural background might affect the coping strategy. Practicing religion and praying or meditating might be essential factors in coping with psychological distress and a key to adapt to the COVID-19 pandemic.
背景肺科住院医师是医院COVID-19一线工作人员的一部分,可能需要适当的应对策略来管理压力。在这里,我们描述了他们在COVID-19大流行期间的心理健康状况和应对策略。方法:对某三级转诊医院肺病住院医师的压力、焦虑、抑郁和应对策略进行队列研究。调查问卷在2020年8月至2021年6月之间的4个时间点进行。DASS-21问卷测量抑郁、焦虑和压力,Brief COPE评估应对策略。结果在2020年8月、2020年10月、2021年2月和2021年6月4个时间点填写问卷的住院医师总数分别为60人、93人、96人和94人,平均应激水平分别为4.3、6.1、5.4和6.3。在研究期间,抑郁、压力和焦虑的发生率较低,大多为轻度或中度。然而,2021年6月,当疫情达到顶峰时,中度焦虑略有增加。绝大多数(95.8%)具有与宗教信仰相关的有效应对策略。结论有效的应对策略可有效保护肺住院医师在疫情期间的心理健康。此外,社会人口和文化背景也可能影响应对策略。从事宗教活动、祈祷或冥想可能是应对心理困扰的重要因素,也是适应新冠肺炎大流行的关键。
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引用次数: 0
A rare case of migration of ballistic projectile from left to right main bronchus 弹道导弹从左主支气管向右主支气管迁移的罕见病例
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-02 DOI: 10.13181/mji.cr.226125
Edwin Yosef Widjaja, Dhihintia Jiwangga, Chikita Nur Rachmi
A foreign body in the bronchus due to a ballistic projectile is very uncommon. A 45-year-old man presented to the hospital after being accidentally shot. The initial radiographic assessment found a bullet in his left thoracic cavity. With the help of an X-ray, an urgent left posterolateral thoracotomy was conducted, but no foreign body was found. The foreign body had migrated to the contralateral chest cavity, as determined by the C-arm. On the following day, a thorax computed tomography scan was conducted, and it was discovered that the foreign body had already migrated to the right lower bronchus. A right thoracotomy was then performed to remove the foreign body. He was moved to the intensive care unit and discharged with a stable condition. In conclusion, migration of a foreign body in the bronchus is rare. A thorough strategy is required to prevent the object from migrating even further.
由弹道导弹引起的支气管异物是非常罕见的。一名45岁男子在意外中枪后被送往医院。初步的放射学评估发现他的左胸腔中有一颗子弹。在X光片的帮助下,紧急进行了左后外侧开胸手术,但没有发现异物。根据C型臂的测定,异物已转移到对侧胸腔。第二天,进行了胸部计算机断层扫描,发现异物已经转移到右下支气管。然后进行右胸切开术以去除异物。他被转移到重症监护室,出院后病情稳定。总之,异物在支气管内的迁移是罕见的。需要一个彻底的策略来防止对象进一步迁移。
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引用次数: 0
Factors associated with global cognitive impairment in epilepsy patients: a cross-sectional study in Mataram, Indonesia 与癫痫患者整体认知障碍相关的因素:印度尼西亚马塔拉姆的一项横断面研究
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-11-10 DOI: 10.13181/mji.oa.226118
Herpan Syafii Harahap, Mohammad Rizki, Deasy Irawati
BACKGROUND Cognitive impairment is a major complication of epilepsy. This study aimed to investigate the factors associated with the prevalence of cognitive impairment in patients with epilepsy in Mataram, Indonesia. METHODS This cross-sectional study involved 155 consecutive outpatients with epilepsy at Mataram General Hospital, Mutiara Sukma Mental Hospital, and Siti Hajar Hospital, Mataram, Indonesia between September 2017 and August 2020. Data on the patient’s demographic characteristics, epilepsy, treatment variables, and global cognitive status were collected. The association between the determinants of epilepsy-associated cognitive impairment and the prevalence of epilepsy-associated global cognitive impairment was analyzed using logistic regression. RESULTS The prevalence of epilepsy-associated global cognitive impairment was 83.9% and related to a low level of education (odds ratio [OR] = 5.24, 95% confidence interval [CI] = 1.93–14.20), early age at onset (OR = 7.85, 95% CI = 0.82–33.79), and long duration of epilepsy (OR = 8.47, 95% CI = 1.95–36.88). CONCLUSIONS A high prevalence of epilepsy-associated global cognitive impairment was observed in Mataram and was associated with a low level of education, early age at onset, and long duration of epilepsy.
背景:认知障碍是癫痫的主要并发症。本研究旨在调查与印尼马塔兰地区癫痫患者认知障碍患病率相关的因素。方法:本横断面研究纳入了2017年9月至2020年8月期间在印度尼西亚马塔兰市马塔兰综合医院、Mutiara Sukma精神病院和Siti Hajar医院连续就诊的155例癫痫患者。收集患者的人口统计学特征、癫痫、治疗变量和整体认知状态的数据。使用逻辑回归分析癫痫相关认知障碍的决定因素与癫痫相关整体认知障碍患病率之间的关系。结果癫痫相关整体认知障碍患病率为83.9%,与受教育程度低(比值比[OR] = 5.24, 95%可信区间[CI] = 1.93 ~ 14.20)、发病年龄早(OR = 7.85, 95% CI = 0.82 ~ 33.79)、癫痫持续时间长(OR = 8.47, 95% CI = 1.95 ~ 36.88)有关。结论:Mataram地区癫痫相关整体认知障碍患病率较高,且与受教育程度低、发病年龄早、癫痫持续时间长有关。
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引用次数: 3
Stress among healthcare workers during the COVID-19 pandemic and the determinant factors: a cross-sectional study COVID-19大流行期间医护人员的压力及其决定因素:一项横断面研究
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-11-10 DOI: 10.13181/mji.oa.226030
Muhammad Reza Aditya, M. Mansyur, M. I. Mokoagow, N. P. Adi, Dewi Yunia, Fitriani, Heriani Tobing, J. Pujo, H. Kallel
BACKGROUND During the COVID-19 pandemic, there has been an increase in workload, as well as greater vigilance and compliance at work. Healthcare workers must perform their duties while facing the fear of COVID-19, which can trigger and/or aggravate stress. This study aimed to obtain the determinant factors of stress among healthcare workers during the pandemic by emphasizing the change in the psychosocial situation at the hospital. METHODS This cross-sectional study was conducted from January to March 2021 using an online questionnaire consisting of personal and occupational questionnaires, as well as the validated stressor and stress questionnaires using validity and reliability tests (Cronbach’s alpha 0.8 and 0.9). For the multivariate analysis, multiple logistic regression was used to identify the determinant factors (p<0.05). Data were analyzed using SPSS software version 20 (IBM Corp., USA). RESULTS Determinant factors of the occurrence of moderate–severe stress were the alteration of stressors including age (aOR = 1.9), working hours (aOR = 1.9), work zone (aOR = 2.7), limited facilities and resources (aOR = 6.2), risk of disease transmission (aOR = 0.3), and personal work demands (aOR = 2.1). CONCLUSIONS In addition to the younger age, the determinant factors of the incidence of moderate–severe stress in healthcare workers during the COVID-19 pandemic at the hospitals were work-related conditions. However, they remained controllable to prevent stress among healthcare workers in the peak load work situations such as a pandemic.
背景:在2019冠状病毒病大流行期间,工作量有所增加,工作中的警惕性和合规性也有所提高。医护人员必须在面对COVID-19的恐惧时履行职责,这可能引发和/或加剧压力。本研究旨在通过强调医院社会心理状况的变化,获得大流行期间医护人员压力的决定因素。方法本横断面研究于2021年1月至3月进行,采用在线问卷,包括个人和职业问卷,以及经过验证的压力源和压力问卷,采用效度和信度检验(Cronbach 's alpha 0.8和0.9)。多因素分析采用多元logistic回归分析确定影响因素(p<0.05)。数据分析使用SPSS软件版本20 (IBM Corp., USA)。结果年龄(aOR = 1.9)、工作时间(aOR = 1.9)、工作区域(aOR = 2.7)、设施资源受限(aOR = 6.2)、疾病传播风险(aOR = 0.3)、个人工作需求(aOR = 2.1)等应激源改变是中重度应激发生的决定因素。结论2019冠状病毒病疫情期间医院医务人员中重度应激发生率的决定因素除年龄外,还包括工作条件。然而,它们仍然是可控的,以防止卫生保健工作者在诸如大流行等高峰负荷工作情况下的压力。
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引用次数: 1
Validity and reliability of the Indonesian version of the new brief job stress questionnaire (short version) for work-related stress screening among office workers 印尼版新的简短工作压力问卷(简短版)用于办公室工作人员工作压力筛查的有效性和可靠性
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-11-02 DOI: 10.13181/mji.oa.226316
N. P. Adi, Ansgar Azurit Virenti Paska Da Lopez, H. Diatri, R. A. Werdhani, D. Soemarko, D. Fitriani
BACKGROUND The short version of the new brief job stress questionnaire (SV-NBJSQ) that is originally in Japanese could evaluate work-related stress in Indonesian office workers. However, it has not been validated in Indonesian. Thus, this study aimed to test the validity and reliability of the Indonesian version of the SV-NBJSQ. METHODS This study was conducted by linguistic and cultural adaptation of the original Japanese questionnaire into Indonesian and continued with exploratory factor analysis, internal consistency, and reliability test of Cronbach’s alpha. Electronic and paper-based data were collected using total sampling from office workers at two companies in Jakarta from December 2017 to August 2018. RESULTS A total of 438 respondents filled the questionnaire. The final version of the questionnaire consisted of 63 items, screened based on a loading factor of >0.4 and 13 factors (dimensions). Each factor had a Cronbach’s alpha of 0.628–0.887, while the entire 63 had 0.904 with a total documented cumulative variation of 64.97%. CONCLUSIONS The Indonesian version of the SV-NBJSQ is valid and reliable. Thus, we may use it as a more suitable, updated, and comprehensive tool to evaluate work-related stress among office workers.
新工作压力简要问卷(SV-NBJSQ)的简短版本最初是日语,可以评估印尼上班族的工作压力。然而,它尚未在印尼语中得到验证。因此,本研究旨在检验印尼语版SV-NBJSQ的效度和信度。方法将原日语问卷翻译成印尼语进行语言和文化调整,并进行探索性因子分析、内部一致性和Cronbach 's alpha信度检验。从2017年12月至2018年8月,通过对雅加达两家公司的办公室工作人员进行总抽样,收集了电子和纸质数据。结果共438名被调查者填写了问卷。最终版本的问卷包括63个项目,根据负载因子b>.4和13个因素(维度)筛选。各因子的Cronbach 's alpha为0.628 ~ 0.887,63个因子的Cronbach 's alpha为0.904,总累积变异为64.97%。结论印尼语版SV-NBJSQ有效可靠。因此,我们可以用它作为一个更合适的、更新的、全面的工具来评估办公室工作人员的工作压力。
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引用次数: 0
Comparison of ultrasonography and fluoroscopy as guides for extracorporeal shock wave lithotripsy in nephrolithiasis patients: a systematic review 超声与透视在肾结石患者体外冲击波碎石中的应用比较:一项系统综述
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-05 DOI: 10.13181/mji.oa.226140
G. Duarsa, Christian Nurtanto Putra, Kevin Ivandi, Kadek Adit Wiryadana, P. Tirtayasa, Firman Pribadi
BACKGROUND Extracorporeal shock wave lithotripsy (ESWL) is one of the first-line treatment options for patients with renal stones <2 cm. The large variability in ESWL results may be due to the stone visualization methods using ultrasonography (USG), fluoroscopy, or a combination of both. This study aimed to review the efficacy and safety of the stone visualization method on the stone-free rate (SFR) and postprocedural complications in nephrolithiasis patients. METHODS We conducted a systematic review of USG and fluoroscopy on ESWL until July 2022, based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We assessed and collected summaries of the screened papers. The main outcomes assessed were the SFR of renal stones and postprocedural complications between imaging modalities. RESULTS A total of 7 studies were assessed, including 6 comparative assessments of USG versus fluoroscopy and 1 comparative assessment of USG and fluoroscopy versus fluoroscopy only. Although all studies showed that USG had a higher SFR than fluoroscopy, only 1 study showed a significant difference (p = 0.008). Additionally, superior results were obtained using a combination of USG and fluoroscopy compared with fluoroscopy only. Most studies agreed that USG was not inferior in post-ESWL complication results. CONCLUSIONS Overall, the use of USG is comparable to fluoroscopy because it does not provide a significant difference in the SFR and complications. In most cases, USG is preferred because of the absence of radiation. The combination of fluoroscopy and USG also provides more promising results than a single modality.
背景体外冲击波碎石术(ESWL)是肾结石<2 cm患者的一线治疗选择之一。ESWL结果的大变异性可能是由于使用超声检查(USG)、透视检查或两者结合的结石可视化方法。本研究旨在探讨结石显像法对肾结石患者结石无结石率(SFR)及术后并发症的疗效和安全性。方法:根据系统评价和荟萃分析指南的首选报告项目,我们对USG和ESWL的透视进行了系统评价,直到2022年7月。我们评估并收集筛选论文的摘要。评估的主要结果是肾结石的SFR和成像方式之间的术后并发症。结果共评估了7项研究,包括6项USG与透视的比较评估,1项USG和透视与仅透视的比较评估。虽然所有研究都显示USG的SFR高于透视,但只有1项研究显示有显著差异(p = 0.008)。此外,USG和x线透视联合使用比单独使用x线透视获得更好的结果。大多数研究一致认为USG在eswl后并发症的结果上并不差。总的来说,USG的使用与透视相当,因为它在SFR和并发症方面没有显着差异。在大多数情况下,USG是首选,因为没有辐射。与单一方式相比,透视和超声心动图的结合也提供了更有希望的结果。
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引用次数: 2
RAGE and HMGB1 expressions in fetal membranes of premature rupture of membranes patients 胎膜早破患者胎膜RAGE和HMGB1的表达
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-09-22 DOI: 10.13181/mji.oa.226099
Ketut Edy Sudiarta, Cindy Jennilyn Candra, Joan Khan, Rahadianto, Fitri Handajani
BACKGROUND Premature rupture of membranes (PROM) often occurs in pregnancy. The fetal membrane weakening is caused by inflammation involving receptor activation for advanced glycation end-products (RAGE) and high mobility group box protein 1 (HMGB1). The associations between RAGE and HMGB1 with PROM are rarely studied. Hence, this study aimed to determine those associations in fetal membranes with PROM occurrence. METHODS This case-control study was conducted at Dr. Ramelan Central Naval Hospital, Surabaya, Indonesia, from August to November 2019. The subjects, determined using a non-probability sampling method (a saturated sample), were divided into PROM and normal pregnancy with intact fetal membranes (control) groups. Fetal membrane specimens were collected during vaginal and cesarean section deliveries. The expressions of RAGE and HMGB1 were determined using the immunohistochemical method and further analyzed using the Mann–Whitney U test. RESULTS The expression of RAGE in fetal membranes with PROM was significantly higher than the control (52.74% versus 14.9% expression/mm2, p<0.001), as well as the expression of HMGB1 (45.9% versus 8.5% expression/mm2, p<0.001). CONCLUSIONS The higher expressions of RAGE and HMGB1 in fetal membranes were associated with PROM.
胎膜早破(PROM)常见于妊娠期。胎儿膜弱化是由炎症引起的,涉及晚期糖基化终末产物(RAGE)和高迁移率组框蛋白1 (HMGB1)的受体激活。RAGE和HMGB1与PROM之间的关系很少被研究。因此,本研究旨在确定胎膜与早PROM发生的关系。方法本病例对照研究于2019年8月至11月在印度尼西亚泗水拉梅兰海军中心医院进行。受试者采用非概率抽样方法(饱和样本),分为胎膜早破组和胎膜完整的正常妊娠组(对照组)。在阴道和剖宫产分娩时采集胎膜标本。免疫组化法检测RAGE和HMGB1的表达,Mann-Whitney U检验分析。结果RAGE在胎膜中表达量(52.74%比14.9%表达量/mm2, p<0.001)和HMGB1表达量(45.9%比8.5%表达量/mm2, p<0.001)显著高于对照组。结论RAGE和HMGB1在胎膜中的高表达与胎膜早破相关。
{"title":"RAGE and HMGB1 expressions in fetal membranes of premature rupture of membranes patients","authors":"Ketut Edy Sudiarta, Cindy Jennilyn Candra, Joan Khan, Rahadianto, Fitri Handajani","doi":"10.13181/mji.oa.226099","DOIUrl":"https://doi.org/10.13181/mji.oa.226099","url":null,"abstract":"BACKGROUND Premature rupture of membranes (PROM) often occurs in pregnancy. The fetal membrane weakening is caused by inflammation involving receptor activation for advanced glycation end-products (RAGE) and high mobility group box protein 1 (HMGB1). The associations between RAGE and HMGB1 with PROM are rarely studied. Hence, this study aimed to determine those associations in fetal membranes with PROM occurrence. \u0000METHODS This case-control study was conducted at Dr. Ramelan Central Naval Hospital, Surabaya, Indonesia, from August to November 2019. The subjects, determined using a non-probability sampling method (a saturated sample), were divided into PROM and normal pregnancy with intact fetal membranes (control) groups. Fetal membrane specimens were collected during vaginal and cesarean section deliveries. The expressions of RAGE and HMGB1 were determined using the immunohistochemical method and further analyzed using the Mann–Whitney U test. \u0000RESULTS The expression of RAGE in fetal membranes with PROM was significantly higher than the control (52.74% versus 14.9% expression/mm2, p<0.001), as well as the expression of HMGB1 (45.9% versus 8.5% expression/mm2, p<0.001). \u0000CONCLUSIONS The higher expressions of RAGE and HMGB1 in fetal membranes were associated with PROM.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47948020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carotid bypass surgery for a persistent neck tumor after multiple treatments: a case report 颈动脉搭桥手术治疗多次治疗后持续性颈部肿瘤1例报告
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-09-22 DOI: 10.13181/mji.cr.226130
Izry Naomi Lumbantobing, Mohd Razif Mohamad Yunus, A. Z. Mat Saad
Carotid artery involvement in head and neck cancer is challenging for surgeons and oncologists, particularly in recurrence or residual disease following multiple treatments. However, carotid artery resection and reconstruction can be safely performed in a carefully selected patient with local and regional control benefits despite the potential morbidity and high-risk complications. We presented a case of primary laryngeal cancer treated with chemoradiotherapy, modified radical neck dissection type I for residual neck node disease, and further chemotherapy. Although the primary laryngeal cancer showed a complete response, the residual neck tumor was still unresolved and even involved the carotid artery. Therefore, carotid resection with a combined saphenous vein graft and free flap reconstruction was the treatment of choice for this patient. It is effective and safe, and the risk of morbidity has been accepted.
头颈癌的颈动脉受累对外科医生和肿瘤学家来说是一个挑战,特别是在多次治疗后复发或残留的疾病。然而,颈动脉切除术和重建可以在精心挑选的患者中安全地进行,尽管有潜在的发病率和高风险并发症,但可以获得局部和区域控制的好处。我们报告了一例原发性喉癌的放化疗,改良根治性颈清扫I型治疗残留颈结疾病,并进一步化疗。虽然原发性喉癌表现出完全的反应,但残留的颈部肿瘤仍未得到解决,甚至累及颈动脉。因此,颈动脉切除术联合隐静脉移植和自由皮瓣重建是该患者的治疗选择。它是有效和安全的,发病率的风险已被接受。
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引用次数: 0
The struggles of regional journals to gain international visibility 区域性期刊努力获得国际知名度
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-08-31 DOI: 10.13181/mji.ed.226297
S. A. Jusman
[No abstract available]
[无可用摘要]
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引用次数: 0
Kidney function profile before, during, and after Ramadan fasting in healthy elderly: a prospective cohort study 健康老年人斋月禁食前、期间和之后的肾功能概况:一项前瞻性队列研究
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-08-31 DOI: 10.13181/mji.oa.225730
M. Abdullah, Edy Rizal Wahyudi, Pringgodigdo Nugroho, Andi Alfian
BACKGROUND Kidney function profile is one of the important parameters in determining the health of the elderly. In Indonesia, no study has been conducted on kidney function profile during Ramadan fasting to determine the safety of Ramadan fasting in the elderly. This study aimed to determine the kidney function profile in the elderly who fasted during Ramadan. METHODS This study used a prospective cohort design. The inclusion criteria were elderly aged >60 years undergoing Ramadan fasting in Jatinegara, Jakarta from April to July 2019. Patients with end-stage renal failure who had an acute infection, hypertension crisis, or refused to participate in the study were excluded. Patients who did not fast for 3 consecutive days were dropped out. The kidney function profile was calculated by the estimated glomerular filtration rate (eGFR) using the CKD-EPI formula 1 week before the first day of Ramadan, 3 weeks after the first day of fasting, and 2 weeks after the last day of fasting. Decreased eGFR was defined as having a minimum of 20% eGFR decline during or after the fasting period. Bivariate analysis was performed using McNemar or Cochran tests. RESULTS 2 patients had eGFR decline during fasting, and 7 patients had eGFR decline after fasting. The median eGFR before, during, and after fasting were 81.5, 88.7, and 76.8 ml/min/1.73 m², respectively. A total of 1.4% of subjects had decreased eGFR during Ramadan, while 9.1% had decreased eGFR after Ramadan. However, the changes were not statistically significant. CONCLUSIONS Although most elderly had lower eGFR following Ramadan fasting compared to before and during Ramadan, only individuals with several comorbidities had significant changes of kidney function.
背景:肾功能状况是判断老年人健康状况的重要指标之一。在印度尼西亚,尚未对斋月禁食期间的肾功能状况进行研究,以确定老年人斋月禁食的安全性。本研究旨在确定在斋月期间禁食的老年人的肾功能状况。方法本研究采用前瞻性队列设计。纳入标准为2019年4月至7月在雅加达贾提内加拉(Jatinegara)进行斋月禁食的60岁至60岁老年人。有急性感染、高血压危重或拒绝参加研究的终末期肾衰竭患者被排除在外。没有连续禁食3天的患者被淘汰。在斋月第一天前1周、禁食第一天后3周和禁食最后一天后2周,使用CKD-EPI公式计算肾小球滤过率(eGFR)来计算肾功能。eGFR下降定义为在禁食期间或禁食后eGFR下降至少20%。采用McNemar或Cochran检验进行双变量分析。结果2例患者空腹时eGFR下降,7例患者空腹后eGFR下降。空腹前、空腹中和空腹后的中位eGFR分别为81.5、88.7和76.8 ml/min/1.73 m²。在斋月期间,有1.4%的受试者eGFR下降,而在斋月后,有9.1%的受试者eGFR下降。然而,这些变化在统计学上并不显著。结论:虽然大多数老年人在斋月禁食后eGFR较斋月前和斋月期间降低,但只有患有几种合并症的个体肾功能有显著变化。
{"title":"Kidney function profile before, during, and after Ramadan fasting in healthy elderly: a prospective cohort study","authors":"M. Abdullah, Edy Rizal Wahyudi, Pringgodigdo Nugroho, Andi Alfian","doi":"10.13181/mji.oa.225730","DOIUrl":"https://doi.org/10.13181/mji.oa.225730","url":null,"abstract":"BACKGROUND Kidney function profile is one of the important parameters in determining the health of the elderly. In Indonesia, no study has been conducted on kidney function profile during Ramadan fasting to determine the safety of Ramadan fasting in the elderly. This study aimed to determine the kidney function profile in the elderly who fasted during Ramadan. \u0000METHODS This study used a prospective cohort design. The inclusion criteria were elderly aged >60 years undergoing Ramadan fasting in Jatinegara, Jakarta from April to July 2019. Patients with end-stage renal failure who had an acute infection, hypertension crisis, or refused to participate in the study were excluded. Patients who did not fast for 3 consecutive days were dropped out. The kidney function profile was calculated by the estimated glomerular filtration rate (eGFR) using the CKD-EPI formula 1 week before the first day of Ramadan, 3 weeks after the first day of fasting, and 2 weeks after the last day of fasting. Decreased eGFR was defined as having a minimum of 20% eGFR decline during or after the fasting period. Bivariate analysis was performed using McNemar or Cochran tests. \u0000RESULTS 2 patients had eGFR decline during fasting, and 7 patients had eGFR decline after fasting. The median eGFR before, during, and after fasting were 81.5, 88.7, and 76.8 ml/min/1.73 m², respectively. A total of 1.4% of subjects had decreased eGFR during Ramadan, while 9.1% had decreased eGFR after Ramadan. However, the changes were not statistically significant. \u0000CONCLUSIONS Although most elderly had lower eGFR following Ramadan fasting compared to before and during Ramadan, only individuals with several comorbidities had significant changes of kidney function.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47205796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Medical Journal of Indonesia
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