Pub Date : 2022-09-27DOI: 10.4274/meandros.galenos.2022.23500
Gülsüm Sena Çiriş, E. Altintas
{"title":"Comparison of Fracture Strength of Modified PEEK, Nanohybrid Ceramic, Monolithic Zirconium Endocrowns Produced with CAD/CAM System","authors":"Gülsüm Sena Çiriş, E. Altintas","doi":"10.4274/meandros.galenos.2022.23500","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2022.23500","url":null,"abstract":"","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43652845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-05DOI: 10.4274/meandros.galenos.2021.35762
M. Tayman, Esma Sarıçam
{"title":"Periodontal and Periapical Effects of Severity of Fremitus Due to Chronic Occlusal Trauma on Mandibular Incisors","authors":"M. Tayman, Esma Sarıçam","doi":"10.4274/meandros.galenos.2021.35762","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2021.35762","url":null,"abstract":"","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44678210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2020.97752
Ç. Esen, A. Esen, Arif Yiğit Güler, D. Menziletoğlu, Ahmet Ertan Soganci
Objective: The aim of this retrospective study was to evaluate the changes in alveolar bone height (ABH) and buccal bone thickness (BBT) of the maxillary teeth after surgically assisted rapid maxillary expansion (SARME) using cone-beam computed tomography (CBCT). Materials and Methods: A total of 9 patients with preoperative and postoperative CBCT records were included in this study. All patients underwent SARME and all of them received a modified acrylic bonded appliance as a maxillary expander. CBCT images were taken before SARME (T1) and after a consolidation period of 3 to 4 months (T2). ABH was determined by measuring the distance from the cemento-enamel junction to the alveolar crest on CBCT images. To evaluate BBT, two different points were identified along the root surface. Results: Alveolar bone loss (ABL) detected between T1 and T2 ABH measurements was statistically significant at all sites of each tooth. There was a statistically significant decrease in BBT at all measured points of each tooth between the T1 and T2 measurements. Conclusion: SARME with modified acrylic-bonded appliances causes ABL and a decrease in BBT, which increases the risk of tooth loss and gingival recession.
目的:采用锥形束计算机断层扫描(CBCT)评价上颌快速扩张术(SARME)后上颌牙槽骨高度(ABH)和颊骨厚度(BBT)的变化。材料与方法:本研究共纳入9例术前和术后CBCT记录的患者。所有患者均行sme手术，并使用改良丙烯酸粘接矫治器作为上颌扩张器。术前(T1)和实变期3 ~ 4个月后(T2)分别进行CBCT成像。通过测量CBCT图像上牙骨质-牙釉质交界处到牙槽嵴的距离来确定ABH。为了评估BBT，沿着根表面确定了两个不同的点。结果:T1和T2 ABH测量时各牙体各部位的牙槽骨丢失(Alveolar bone loss, ABL)均有统计学意义。在T1和T2测量之间，每颗牙齿所有测点的BBT均有统计学意义的下降。结论:改良丙烯酸粘接矫治器的sme可引起ABL和BBT的降低，增加了牙齿脱落和牙龈萎缩的风险。
{"title":"Assessment of Alveolar Bone Loss and Buccal Bone Thickness After Surgically Assisted Rapid Maxillary Expansion","authors":"Ç. Esen, A. Esen, Arif Yiğit Güler, D. Menziletoğlu, Ahmet Ertan Soganci","doi":"10.4274/meandros.galenos.2020.97752","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2020.97752","url":null,"abstract":"Objective: The aim of this retrospective study was to evaluate the changes in alveolar bone height (ABH) and buccal bone thickness (BBT) of the maxillary teeth after surgically assisted rapid maxillary expansion (SARME) using cone-beam computed tomography (CBCT). Materials and Methods: A total of 9 patients with preoperative and postoperative CBCT records were included in this study. All patients underwent SARME and all of them received a modified acrylic bonded appliance as a maxillary expander. CBCT images were taken before SARME (T1) and after a consolidation period of 3 to 4 months (T2). ABH was determined by measuring the distance from the cemento-enamel junction to the alveolar crest on CBCT images. To evaluate BBT, two different points were identified along the root surface. Results: Alveolar bone loss (ABL) detected between T1 and T2 ABH measurements was statistically significant at all sites of each tooth. There was a statistically significant decrease in BBT at all measured points of each tooth between the T1 and T2 measurements. Conclusion: SARME with modified acrylic-bonded appliances causes ABL and a decrease in BBT, which increases the risk of tooth loss and gingival recession.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44488135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2021.16046
Nezaket Ezgi Özer, Betul Karaca, C. Gürhan, H. Boyacıoğlu, Umut Aykutlu, P. Güneri
Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clinical features of lesions were analyzed using chi-square test, Fisher’s Exact test of Independence and discriminant function analysis. Results: Margins, lymphadenopathy, patient’s self-awareness of the lesion associated with mass effect, surface texture, colour, ulceration, loss of function and pain were significant parameters indicating the risk of malignancy (p<0.05). Analyses of the parameters related to the high risk of malignancy have led to a statistical model for clinical differentiation of benign lesions from malignancies with an accuracy of 91.4% (p=0.016). The statistical model demonstrated that the most important discriminative features were margins, surface texture, patient’s self-awareness, lymphadenopathy, loss of function, ulceration, colour, and pain, respectively. Conclusion: In our study, age, gender, duration and localization did not anticipate the nature of the lesion. Our statistical model showed that irregular/indistinct margins and surface textures and the presence of lymphadenopathy have a higher risk of malignancy.
{"title":"Are Clinical Predictors of Oral Malignancy Risk Changing? A Sample Study","authors":"Nezaket Ezgi Özer, Betul Karaca, C. Gürhan, H. Boyacıoğlu, Umut Aykutlu, P. Güneri","doi":"10.4274/meandros.galenos.2021.16046","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2021.16046","url":null,"abstract":"Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clinical features of lesions were analyzed using chi-square test, Fisher’s Exact test of Independence and discriminant function analysis. Results: Margins, lymphadenopathy, patient’s self-awareness of the lesion associated with mass effect, surface texture, colour, ulceration, loss of function and pain were significant parameters indicating the risk of malignancy (p<0.05). Analyses of the parameters related to the high risk of malignancy have led to a statistical model for clinical differentiation of benign lesions from malignancies with an accuracy of 91.4% (p=0.016). The statistical model demonstrated that the most important discriminative features were margins, surface texture, patient’s self-awareness, lymphadenopathy, loss of function, ulceration, colour, and pain, respectively. Conclusion: In our study, age, gender, duration and localization did not anticipate the nature of the lesion. Our statistical model showed that irregular/indistinct margins and surface textures and the presence of lymphadenopathy have a higher risk of malignancy.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42349122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2021.03274
Can Topkara, K. Yılmaz, M. Gündoğar, G. Uslu, T. Özyürek
Objective: This study aimed to assess the pull-out bonding resistance of FiberSite and RelyX Fiber posts constructed from core structures using various resin cement. Materials and Methods: Sixty mandibular premolar teeth were horizontally sectioned to create a root canal length of 15±1 mm. Up to size #40, samples were prepared and obturated with gutta-percha and root canal sealer. Three groups of specimens (n=20) were formed. FiberSite posts were luted and built-up using Clearfil DC Core Plus in Group 1, RelyX Fiber posts were luted and built-up using Clearfil DC Core Plus in Group 2, and RelyX Fiber Posts were luted and built-up using Filtek Bulk Fill Posterior in Group 3. Each specimen was vertically positioned in a universal testing machine and rotated at 0.5 mm/min until it dislodged. One-way ANOVA and post hoc tests were used to evaluate the data. Results: The bonding strength of FiberSite posts was higher than that of RelyX Fiber posts (p<0.05). Clearfil DC Core Plus-built RelyX Fiber Posts exhibited higher bond strength than Filtek Bulk Fill Posterior-built posts (p<0.05). Conclusion: FiberSite posts provide better root canal dentin retention than RelyX Fiber posts with different core materials. olarak kesildi. Örneklerin kök kanalları #40’a kadar prepere edildi ve guta-perka ve kanal patı kullanılarak kök kanal dolguları yapıldı. Örnekler daha sonra 3 gruba ayrıldı (n=20). Grup 1’de FiberSite postları Clearfil DC Core Plus ile simante edildi. Grup 2’de RelyX Fiber postlarının simantasyonu ve kor yapıları, Clearfil DC Core Plus ile yapıldı. Grup 3’te, Clearfil DC Core Plus ile simante edilen RelyX Fiber postlarının kor yapıları Filtek Bulk Fill Posterior ile yapıldı. Tüm örneklere, universal test cihazında kırılma gerçekleşinceye kadar dikey yönde 0,5 mm/dak sabit kuvvet uygulandı. Verilere tek yönlü varyans analizi yapıldı ve post hoc testleri ile analiz edildi.
目的：本研究旨在评估FiberSite和RelyX纤维桩的抗拔性，这两种桩由使用各种树脂水泥的核心结构制成。材料和方法：将60颗下颌前臼齿水平切片，形成15±1mm的根管长度。制备尺寸为#40的样品，并用牙胶和根管封闭剂塞住。形成了三组标本（n=20）。FiberSite桩在第1组中使用Clearfil DC Core Plus进行稀释和构建，RelyX纤维桩在第2组中使用Clearfil DC Core Plus进行稀释并构建，而RelyX光纤桩在第3组中使用Filtek Bulk Fill Postior进行稀释和建立。将每个样品垂直放置在通用试验机中，并以0.5 mm/min的速度旋转，直到其移位。使用单向方差分析和事后检验来评估数据。结果：FiberSite桩的粘结强度高于RelyX纤维桩（p<0.05）。Clearfil DC Core Plus构建的RelyX光纤桩的粘结力高于Filtek Bulk Fill Postior构建的桩（p<0.05。奥拉克·凯西尔迪。Örneklerin kök kanalları#40‘a kadar prepere edildi ve guta perka ve kanal patıkullanılarak kök-kanal dolgularıyapıldı。Örnekler daha sonra 3 gruba ayrıldı（n=20）。Grup 1'de FiberSite postlarıClearfil DC Core Plus ile simante edildi。Grup 2'de RelyX Fiber postlarının simantasyonu ve kor yapıları，Clearfil DC Core Plus ile yapşldı。Grup 3’te，Clearfil DC Core Plus ile simante edilen RelyX Fiber postlarının kor yapılarıFiltek Bulk Fill Postior ile yapşldı。Tümörneklere，通用测试cihazında kırılma gerçekleşinceye kadar dikey yönde 0.5 mm/dak sabit kuvvet维吾尔语。Verilere tek yönlüvaryans analizi yapıldıve post-hoc testleri ile analiz edildi。
{"title":"Pull-out Retentive Resistance of Fiber Posts Restored with Different Core Materials","authors":"Can Topkara, K. Yılmaz, M. Gündoğar, G. Uslu, T. Özyürek","doi":"10.4274/meandros.galenos.2021.03274","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2021.03274","url":null,"abstract":"Objective: This study aimed to assess the pull-out bonding resistance of FiberSite and RelyX Fiber posts constructed from core structures using various resin cement. Materials and Methods: Sixty mandibular premolar teeth were horizontally sectioned to create a root canal length of 15±1 mm. Up to size #40, samples were prepared and obturated with gutta-percha and root canal sealer. Three groups of specimens (n=20) were formed. FiberSite posts were luted and built-up using Clearfil DC Core Plus in Group 1, RelyX Fiber posts were luted and built-up using Clearfil DC Core Plus in Group 2, and RelyX Fiber Posts were luted and built-up using Filtek Bulk Fill Posterior in Group 3. Each specimen was vertically positioned in a universal testing machine and rotated at 0.5 mm/min until it dislodged. One-way ANOVA and post hoc tests were used to evaluate the data. Results: The bonding strength of FiberSite posts was higher than that of RelyX Fiber posts (p<0.05). Clearfil DC Core Plus-built RelyX Fiber Posts exhibited higher bond strength than Filtek Bulk Fill Posterior-built posts (p<0.05). Conclusion: FiberSite posts provide better root canal dentin retention than RelyX Fiber posts with different core materials. olarak kesildi. Örneklerin kök kanalları #40’a kadar prepere edildi ve guta-perka ve kanal patı kullanılarak kök kanal dolguları yapıldı. Örnekler daha sonra 3 gruba ayrıldı (n=20). Grup 1’de FiberSite postları Clearfil DC Core Plus ile simante edildi. Grup 2’de RelyX Fiber postlarının simantasyonu ve kor yapıları, Clearfil DC Core Plus ile yapıldı. Grup 3’te, Clearfil DC Core Plus ile simante edilen RelyX Fiber postlarının kor yapıları Filtek Bulk Fill Posterior ile yapıldı. Tüm örneklere, universal test cihazında kırılma gerçekleşinceye kadar dikey yönde 0,5 mm/dak sabit kuvvet uygulandı. Verilere tek yönlü varyans analizi yapıldı ve post hoc testleri ile analiz edildi.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43876588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The complete blood count parameters and biochemical biomarkers important for the follow-up of patients in the inflammatory process of coronavirus disease 2019 (COVID-19) inpatients in the ward, and intensive care were analysed retrospectively. Materials and Methods: One hundred thirty inpatients in the intensive care and 147 inpatients in the COVID-19 ward were included in this study. Additionally, 47 healthy people were added as a control group. Whole blood parameters [white blood cell (WBC), lymphocyte, monocytes, platelet, neutrophil, monocyte/ lymphocyte (MLR), neutrophil/lymphocyte (NLR)], ferritin, C-reactive protein (CRP), procalcitonin, erythrocyte sedimentation ratio (ESR) and albumin values of these patients and individuals were analyzed retrospectively. Obtained laboratory values were compared. Results: The procalcitonin, CRP, ESR, WBC, neutrophil, NLR, MLR, ferritin and procalcitonin values of the patients the intensive care patients were higher than the other two groups (p<0.001). However, the albumin and lymphocyte levels of the patients in the intensive care unit were lower (p<0.001). Additionally, the CRP and ESR values of the inpatients in the ward were higher than those in the control group (p<0.001). Conclusion: Hematological findings such as lymphocytes, NLR, WBC and inflammatory findings such as procalcitonin, ESR, CRP, and ferritin are associated with disease severity. Additionally, increased NLR levels may indicate aggravation of the inflammatory process and the possibility of intensive care admission. Therefore, monitoring of inflammatory findings, and NLR, can help predict and treat the prognosis of COVID-19.
{"title":"The Relationship Between Inflammatory Indicators and the Severity of the Disease in Coronavirus Disease","authors":"Recai Aci, Mukadder Erdem, Göksenin Ünlügüzel Üstün, Utku Duran, Adem Keskin, M. Bilgin","doi":"10.4274/meandros.galenos.2021.65477","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2021.65477","url":null,"abstract":"Objective: The complete blood count parameters and biochemical biomarkers important for the follow-up of patients in the inflammatory process of coronavirus disease 2019 (COVID-19) inpatients in the ward, and intensive care were analysed retrospectively. Materials and Methods: One hundred thirty inpatients in the intensive care and 147 inpatients in the COVID-19 ward were included in this study. Additionally, 47 healthy people were added as a control group. Whole blood parameters [white blood cell (WBC), lymphocyte, monocytes, platelet, neutrophil, monocyte/ lymphocyte (MLR), neutrophil/lymphocyte (NLR)], ferritin, C-reactive protein (CRP), procalcitonin, erythrocyte sedimentation ratio (ESR) and albumin values of these patients and individuals were analyzed retrospectively. Obtained laboratory values were compared. Results: The procalcitonin, CRP, ESR, WBC, neutrophil, NLR, MLR, ferritin and procalcitonin values of the patients the intensive care patients were higher than the other two groups (p<0.001). However, the albumin and lymphocyte levels of the patients in the intensive care unit were lower (p<0.001). Additionally, the CRP and ESR values of the inpatients in the ward were higher than those in the control group (p<0.001). Conclusion: Hematological findings such as lymphocytes, NLR, WBC and inflammatory findings such as procalcitonin, ESR, CRP, and ferritin are associated with disease severity. Additionally, increased NLR levels may indicate aggravation of the inflammatory process and the possibility of intensive care admission. Therefore, monitoring of inflammatory findings, and NLR, can help predict and treat the prognosis of COVID-19.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45931444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2022.86729
F. Şirinyıldız, G. Cesur
Objective: The aim of this study was to investigate the effects of apelin (APL)-13 in a trinitrobenzenesulphonic acid (TNBS) induced experimental colitis model. It is also to test whether APL-13 has an antioxidant effect in addition to its proliferative and anti-inflammatory effect in colon inflammation by looking at antioxidant parameters. Materials and Methods: Forty-five Wistar albino rats were divided into six groups as control, sham control, APL control, colitis (TNBS), colitis + ethanol, and colitis + APL. The control group was fed a standard diet without any treatment. The sham group was treated in the same colitis group, but saline was given instead of TNBS. The APL control group was given APL, but no colitis was induced. Colitis + ethanol and colitis + APL group was given ethanol and 100 µg/kg APL intraperitoneally (i.p.) for 3 days after colitis. For the biochemical analysis of the tissues, levels of myeloperoxidase (MPO), malonyldialdehyde (MDA), superoxide dismutase, catalase and glutathione were measured. Histopathological observations occurred. Results: There were significantly increased MDA and MPO levels the animals that were grouped as TNBS and the antioxidant parameters were shown significantly decreased. Administration of APL-13 did make a significant decrease in colon MDA and MPO levels and antioxidant parameters were shown significantly increased compared to TNBS groups. The histological image of the TNBS + APL group was observed to have reduced mucosal damage, necrosis and edema compared with the TNBS group. Conclusion: In conclusion, our study showed that APL-13 has therapeutic effects on TNBS induced ulcerative colitis. APL-13 may be an effective substance that can be used to eliminate the negative effects of ulcerative colitis.
{"title":"Investigation of the Effects of Apelin 13 on Experimental Ulcerative Colitis","authors":"F. Şirinyıldız, G. Cesur","doi":"10.4274/meandros.galenos.2022.86729","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2022.86729","url":null,"abstract":"Objective: The aim of this study was to investigate the effects of apelin (APL)-13 in a trinitrobenzenesulphonic acid (TNBS) induced experimental colitis model. It is also to test whether APL-13 has an antioxidant effect in addition to its proliferative and anti-inflammatory effect in colon inflammation by looking at antioxidant parameters. Materials and Methods: Forty-five Wistar albino rats were divided into six groups as control, sham control, APL control, colitis (TNBS), colitis + ethanol, and colitis + APL. The control group was fed a standard diet without any treatment. The sham group was treated in the same colitis group, but saline was given instead of TNBS. The APL control group was given APL, but no colitis was induced. Colitis + ethanol and colitis + APL group was given ethanol and 100 µg/kg APL intraperitoneally (i.p.) for 3 days after colitis. For the biochemical analysis of the tissues, levels of myeloperoxidase (MPO), malonyldialdehyde (MDA), superoxide dismutase, catalase and glutathione were measured. Histopathological observations occurred. Results: There were significantly increased MDA and MPO levels the animals that were grouped as TNBS and the antioxidant parameters were shown significantly decreased. Administration of APL-13 did make a significant decrease in colon MDA and MPO levels and antioxidant parameters were shown significantly increased compared to TNBS groups. The histological image of the TNBS + APL group was observed to have reduced mucosal damage, necrosis and edema compared with the TNBS group. Conclusion: In conclusion, our study showed that APL-13 has therapeutic effects on TNBS induced ulcerative colitis. APL-13 may be an effective substance that can be used to eliminate the negative effects of ulcerative colitis.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42493388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2015.2217
S. N. Avcıoğlu, E. Zafer, S. O. Altınkaya, S. Demircan Sezer, H. Yüksel, M. Küçük
Labial adhesions are generally observed in the premenarchal and postmenopausal period. They are rarely seen in adulthood. Here, two labial fusion cases in the reproductive period are discussed. In the first case, 38-year-old virgin woman presented with anuria to the emergency unit. On her physical examination, labia were fused totally including periurethral area. His history revealed that she was mentally retarded and had primary amenorrhea. She had poor selfcare. On her genital examination, she had secondary sexual characteristics, including axially-pubic hair and breast development at Tanner stage-5. In her surgical treatment, the labia were overturned and a well-defined introitus was constituted. After the operation, topical estrogen prescribed. In second case, a forty-two year old woman with Behçet’s disease presented with dysuria and difficulty in voiding for about one month. Her obstetric examination revealed that she had two vaginal births. On pelvic examination, genital ulcer was determined on the labium. Besides, adhesion almost completely fused into the bilateral labia minora. For surgical treatment, manual separation technique was used under general anesthesia. After the operation, topical steroid was prescribed. Labial adhesions are observed, especially in the premenarchal period. However, they may be very rarely seen in the reproductive period due to local inflammation and circulating low estrogen levels. Topical estrogens, topical steroids, oral estrogen treatment, manual separation under anesthesia or without anesthesia, sharp or blunt dissection under anesthesia are alternative treatment methods. The success rates of these treatment methods exceed 90%. Besides, the recurrence rate varies between 4% and 20% with manual and sharp dissection methods.
{"title":"Labial Adhesion in Adulthood: A Report of Two Cases","authors":"S. N. Avcıoğlu, E. Zafer, S. O. Altınkaya, S. Demircan Sezer, H. Yüksel, M. Küçük","doi":"10.4274/meandros.galenos.2015.2217","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2015.2217","url":null,"abstract":"Labial adhesions are generally observed in the premenarchal and postmenopausal period. They are rarely seen in adulthood. Here, two labial fusion cases in the reproductive period are discussed. In the first case, 38-year-old virgin woman presented with anuria to the emergency unit. On her physical examination, labia were fused totally including periurethral area. His history revealed that she was mentally retarded and had primary amenorrhea. She had poor selfcare. On her genital examination, she had secondary sexual characteristics, including axially-pubic hair and breast development at Tanner stage-5. In her surgical treatment, the labia were overturned and a well-defined introitus was constituted. After the operation, topical estrogen prescribed. In second case, a forty-two year old woman with Behçet’s disease presented with dysuria and difficulty in voiding for about one month. Her obstetric examination revealed that she had two vaginal births. On pelvic examination, genital ulcer was determined on the labium. Besides, adhesion almost completely fused into the bilateral labia minora. For surgical treatment, manual separation technique was used under general anesthesia. After the operation, topical steroid was prescribed. Labial adhesions are observed, especially in the premenarchal period. However, they may be very rarely seen in the reproductive period due to local inflammation and circulating low estrogen levels. Topical estrogens, topical steroids, oral estrogen treatment, manual separation under anesthesia or without anesthesia, sharp or blunt dissection under anesthesia are alternative treatment methods. The success rates of these treatment methods exceed 90%. Besides, the recurrence rate varies between 4% and 20% with manual and sharp dissection methods.","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48703693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2021.87004
Yasemin Tin Arslan, Ç. Yenisey
Objective: To investigate the regenerative effects of adipose-derived mesenchymal stem cells (ADMSCs) in immortalized human keratinocyte cells (HaCaT) exposed to ultraviolet B (UVB) rays. Materials and Methods: Epidermal cells were interacted with UVB rays. Then, treatment was applied to ADMSC mediums prepared in different concentrations. Cells that did not receive UVB light were included in the study as a control. Results: With the application of human adipose tissue mesenchymal stem cells to HaCaT cells with different concentrations of media prepared, cell viability increased in both cells that received UVB radiation and those that did not. It has been observed that the said increases are more pronounced, especially in cells that have received UVB rays, reaching the maximum value at 100%, which is the highest stem cell medium concentration. ADMSC medium also had an increasing effect on the migration of UVB (+) cells. In UVB (+) cells, decreased levels of myeloid cell leukemia 1 protein (Mcl-1) and
{"title":"Investigation of the Reparative and Regenerative Effects of Human Adipose Tissue Mesenchymal Stem Cells on Epidermal Cells Exposed to UVB Ray","authors":"Yasemin Tin Arslan, Ç. Yenisey","doi":"10.4274/meandros.galenos.2021.87004","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2021.87004","url":null,"abstract":"Objective: To investigate the regenerative effects of adipose-derived mesenchymal stem cells (ADMSCs) in immortalized human keratinocyte cells (HaCaT) exposed to ultraviolet B (UVB) rays. Materials and Methods: Epidermal cells were interacted with UVB rays. Then, treatment was applied to ADMSC mediums prepared in different concentrations. Cells that did not receive UVB light were included in the study as a control. Results: With the application of human adipose tissue mesenchymal stem cells to HaCaT cells with different concentrations of media prepared, cell viability increased in both cells that received UVB radiation and those that did not. It has been observed that the said increases are more pronounced, especially in cells that have received UVB rays, reaching the maximum value at 100%, which is the highest stem cell medium concentration. ADMSC medium also had an increasing effect on the migration of UVB (+) cells. In UVB (+) cells, decreased levels of myeloid cell leukemia 1 protein (Mcl-1) and","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":"5 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70908898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.4274/meandros.galenos.2022.47113
A. Seyhan, E. Aktürk
Objective: To compare pathological results of colposcopic biopsy and cold knife conization in association with overtreatment and missed diagnosis perspective. Materials and Methods: The data of 72 patients who were referred to the gynecologic oncology clinic because of the presence of atypical cytology and/ or high-risk human papillomavirus and underwent colposcopic biopsy and cold knife conization were retrospectively analyzed. Cases with discordant results were examined, particularly in terms of overtreatment and missed diagnosis. Results: Efficacy of colposcopic biopsy was evaluated; the sensitivity, specificity, positive predictive value, negative predictive
{"title":"Comparison of Colposcopic Biopsy and Conization Results in Association with Overtreatment or Missed Diagnosis","authors":"A. Seyhan, E. Aktürk","doi":"10.4274/meandros.galenos.2022.47113","DOIUrl":"https://doi.org/10.4274/meandros.galenos.2022.47113","url":null,"abstract":"Objective: To compare pathological results of colposcopic biopsy and cold knife conization in association with overtreatment and missed diagnosis perspective. Materials and Methods: The data of 72 patients who were referred to the gynecologic oncology clinic because of the presence of atypical cytology and/ or high-risk human papillomavirus and underwent colposcopic biopsy and cold knife conization were retrospectively analyzed. Cases with discordant results were examined, particularly in terms of overtreatment and missed diagnosis. Results: Efficacy of colposcopic biopsy was evaluated; the sensitivity, specificity, positive predictive value, negative predictive","PeriodicalId":18332,"journal":{"name":"Meandros Medical and Dental Journal","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70909301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：