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Retrospective analysis on prognosis of oral cancer patients according to surgical approaches for effective cancer ablation: swing approach versus visor approach 根据有效消融癌症的手术方法对口腔癌患者预后的回顾性分析:摆动法与面罩法
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-22 DOI: 10.1186/s40902-024-00426-9
Yun-Ho Kim, Jae-Young Yang, Dong-Min Lee, Jae-Yeol Lee, Dae-Seok Hwang, Mi-Heon Ryu, Uk-Kyu Kim
For the surgical treatment of oral cancer, it is sometimes necessary to expand intraoral access within the oral cavity. The “swing approach” that involves lip splitting of the mandible and temporary mandibular osteotomy and the “visor approach” that does not split the lower lip and mandible are mainly used. This study analyzed postoperative outcomes such as complications, recurrence rate, and survival rate by these two approaches. The goal of this study is to evaluate the surgical outcomes of patients using these two approaches, to propose effective perioperative management for oral cancer surgery, and to compare the prognosis of oral cancer patients. From 2005 to 2020, 29 patients who underwent surgery at the Department of Oral and Maxillofacial Surgery of Pusan National University Dental Hospital for oral cancer lesions occurred in the mandible, floor of mouth, and tongue were selected for the study. Based on the surgical approach used, a chart review was conducted on various prognostic clinical factors such as the patients’ sex and age, primary site, TNM stage, histopathologic grade, recurrence and metastasis, postoperative survival rate, adjuvant chemo-radiation therapy, satisfaction with aesthetics/function/swallowing, length of hospital stay, tracheostomy and its duration, and neck dissection and its type. Statistical analysis was conducted using SPSS 25.0 (SPSS Inc., Chicago, IL) through Fisher’s exact t-test. There was no statistically significant difference between two groups in terms of clinical and pathological findings, such as survival rate, the need for adjuvant therapies, and the local recurrence rate. Although better outcomes were observed in terms of function, aesthetics, and postoperative complications in the group with visor approach, there was still no statistically significant difference between two groups. However, the duration of hospital stay was shorter in the visor approach group. There was no statistically significant difference in clinical prognostic factors between the swing approach and the visor approach. Therefore, when choosing between the two approaches for the ablation of oral cancer, it is considered to select the surgical priority approach that can be easy access based on the size and location of the lesion. The visor approach had advantages of aesthetics and healing period.
在口腔癌的手术治疗中,有时需要在口腔内扩大口腔内入路。目前主要采用的是下颌骨唇裂和临时下颌骨截骨的 "摆动法 "和不切开下唇和下颌骨的 "面罩法"。本研究分析了这两种方法的术后效果,如并发症、复发率和存活率。本研究的目的是评估使用这两种方法的患者的手术效果,为口腔癌手术提出有效的围手术期管理建议,并比较口腔癌患者的预后。研究选取了 2005 年至 2020 年期间在釜山大学牙科医院口腔颌面外科接受手术治疗的 29 名下颌骨、口底和舌头口腔癌病变患者。根据所采用的手术方法,对患者的性别和年龄、原发部位、TNM 分期、组织病理学分级、复发和转移、术后生存率、辅助化疗和放疗、对美观/功能/吞咽的满意度、住院时间、气管造口术及其持续时间、颈部切除术及其类型等各种预后临床因素进行了病历回顾。统计分析使用 SPSS 25.0 (SPSS Inc., Chicago, IL) 通过费雪精确 t 检验进行。两组患者的临床和病理结果,如存活率、辅助治疗需求和局部复发率,在统计学上无明显差异。虽然在功能、美观度和术后并发症方面,面罩法组的疗效更好,但两组之间的差异仍无统计学意义。不过,遮盖器入路组的住院时间较短。在临床预后因素方面,摇摆入路法和遮盖器入路法的差异无统计学意义。因此,在选择两种方法消融口腔癌时,应根据病灶的大小和位置,优先选择易于进入的手术方法。遮盖器方法在美观和愈合期方面具有优势。
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引用次数: 0
Advancements in alveolar bone grafting and ridge preservation: a narrative review on materials, techniques, and clinical outcomes 牙槽骨移植和牙嵴保存的进展:材料、技术和临床效果综述
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-16 DOI: 10.1186/s40902-024-00425-w
Suyoung Kim, Seong-Gon Kim
This narrative review systematically explores the progression of materials and techniques in alveolar ridge preservation (ARP). We commence by delineating the evolution from traditional ARP methods to cutting-edge alternatives, including platelet-rich fibrin, injectable bone repair materials, and hydrogel systems. Critical examination of various studies reveals these innovative approaches not only accelerate bone healing but also significantly improve patient-reported outcomes, such as satisfaction, pain perception, and overall quality of life. Emphasis is placed on the correlation between advanced ARP techniques and enhanced patient comfort and clinical efficacy, underscoring their transformative potential in dental implantology. Highlighting the effectiveness of ARP, the implant survival rate over a span of 5 to 7 years was high, showcasing the reliability and success of these methods. Further, patients expressed high aesthetic satisfaction with the soft tissue outcome, evidenced by an average visual analog scale (VAS) score of 94. This positive aesthetic appraisal is linked to the clinical health of implants, potentially due to the employment of tooth-supported surgical guides. The economic analysis reveals a varied cost range for bone graft substitutes ($46.2 to $140) and socket sealing materials ($12 to $189), with a noteworthy correlation between the investment in barrier membranes and the diminished horizontal and vertical ridge resorption. This suggests that membrane usage significantly contributes to preserving ridge dimensions, offering a cost-effective strategy for enhancing ARP outcomes. In conclusion, this review illuminates the significant advancements in ARP, highlighting the shift towards innovative materials and techniques that not only promise enhanced bone regeneration and reduced healing times but also improve patient satisfaction and aesthetic outcomes. The documented high implant survival rate and the beneficial economic implications of membrane use further validate the effectiveness of contemporary ARP strategies, paving the way for their broader adoption in dental implantology.
这篇叙述性综述系统地探讨了牙槽嵴保存(ARP)材料和技术的发展。我们首先描述了从传统 ARP 方法到尖端替代方法的演变过程,包括富血小板纤维蛋白、可注射骨修复材料和水凝胶系统。对各种研究的严格审查表明,这些创新方法不仅能加速骨愈合,还能显著改善患者报告的结果,如满意度、疼痛感和整体生活质量。重点强调了先进的 ARP 技术与提高患者舒适度和临床疗效之间的相关性,突出了其在牙科种植方面的变革潜力。为了突出 ARP 的有效性,种植体在 5 到 7 年间的存活率很高,显示了这些方法的可靠性和成功性。此外,患者对软组织效果的美学满意度也很高,平均视觉模拟量表(VAS)得分为 94 分。这种积极的美学评价与种植体的临床健康状况有关,可能是由于采用了牙齿支持的手术导板。经济分析表明,骨移植替代物(46.2 美元至 140 美元)和牙槽窝密封材料(12 美元至 189 美元)的成本范围各不相同,值得注意的是,隔离膜的投资与水平和垂直牙脊吸收的减少之间存在相关性。这表明,使用隔离膜对保持牙槽嵴的尺寸有很大帮助,为提高 ARP 的效果提供了一种经济有效的策略。总之,本综述揭示了 ARP 的重大进展,强调了向创新材料和技术的转变,这些材料和技术不仅能提高骨再生能力、缩短愈合时间,还能提高患者满意度和美学效果。有据可查的高种植体存活率和膜使用的经济效益进一步验证了当代 ARP 策略的有效性,为其在牙科种植中的广泛应用铺平了道路。
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引用次数: 0
Early oral feeding and its impact on postoperative outcomes in head and neck cancer surgery: a meta-analysis. 早期口服喂养及其对头颈部癌症手术术后效果的影响:一项荟萃分析。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-28 DOI: 10.1186/s40902-024-00421-0
Yomna E Dean, Karam R Motawea, Bdoor Ahmed A Bamousa, Jose J Loayza Pintado, Sameh Samir Elawady, Mohammed Soffar, Jaffer Shah, Kailyn Wilcox, Hani Aiash

Background: Early oral feeding has been previously postulated to contribute to developing postoperative complications following head and neck reconstructive surgeries using free flaps. This study assessed the association between the timing of oral feeding (early vs. late) and postoperative complications and length of hospital stay among these patients.

Method: PubMed, Scopus, Cochrane, and Web of Science were searched using terms such as "oral feeding" and "head or neck cancer." We utilized RevMan software version 5.4 for the analysis. The study defined early oral feeding as feeding within 5-day post-operation, while late oral feeding was defined as feeding after the fifth postoperative day. Five papers that met the inclusion criteria were included in the analysis, with 1097 patients.

Results: The results showed that early feeding was not significantly associated with postoperative fistulas (RR 0.49, 95% CI 0.23 to 1.05, p-value = 0.07), hematoma/seroma (RR 0.71, 95% CI 0.33 to 1.51, p-value = 0.38), or flap failure (RR 0.84, 95% CI = 0.38 to 1.87, p-value = 0.67). However, early oral feeding was significantly associated with shorter hospital stays than late oral feeding (MD -3.18, 95% CI -4.90 to -1.46, p-value = 0.0003).

Conclusion: No significant difference exists between early and late oral feeding regarding the risk of postoperative complications in head and neck cancer (HNC) patients who underwent free flap reconstruction surgery. However, early oral feeding is significantly associated with a shorter hospital stay than late oral feeding. Thus, surgeons should consider implementing early oral feeding after free flap reconstruction in HNC patients.

背景:以前曾有人推测,过早进行口腔喂养会导致使用游离皮瓣进行头颈部整形手术后出现术后并发症。本研究评估了口腔喂养时间(早期与晚期)与这些患者术后并发症和住院时间之间的关系:方法:使用 "口腔喂养 "和 "头颈部癌症 "等术语对 PubMed、Scopus、Cochrane 和 Web of Science 进行了检索。我们使用 RevMan 软件 5.4 版进行分析。研究将早期口腔喂养定义为术后 5 天内的喂养,而晚期口腔喂养则定义为术后第 5 天后的喂养。符合纳入标准的 5 篇论文被纳入分析,共纳入 1097 名患者:结果显示,早期喂养与术后瘘管(RR 0.49,95% CI 0.23 至 1.05,P 值 = 0.07)、血肿/血槽瘤(RR 0.71,95% CI 0.33 至 1.51,P 值 = 0.38)或皮瓣失败(RR 0.84,95% CI = 0.38 至 1.87,P 值 = 0.67)无显著相关性。然而,与晚期口服喂养相比,早期口服喂养明显缩短了住院时间(MD -3.18,95% CI -4.90至-1.46,P值 = 0.0003):在接受游离皮瓣重建手术的头颈癌(HNC)患者中,早期和晚期口服喂养在术后并发症风险方面没有明显差异。不过,与晚期口服喂养相比,早期口服喂养明显缩短了住院时间。因此,外科医生应考虑在 HNC 患者接受游离皮瓣重建手术后尽早进行口腔喂养。
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引用次数: 0
Impact of skeletal muscle mass on postoperative complications in oral cancer surgery. 骨骼肌质量对口腔癌手术术后并发症的影响。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-28 DOI: 10.1186/s40902-024-00417-w
Arisa Fujii, Taiki Suzuki, Katsuhiko Sakai, Nobuyuki Matsuura, Keisuke Sugahara, Akira Katakura, Takeshi Nomura

Background: Sarcopenia is characterized by a progressive and generalized loss of skeletal muscle mass and strength. The aim of this retrospective study was to investigate the impact of skeletal muscle mass on adverse events in free-flap reconstruction for defects after oral cancer resection.

Results: Of 120 patients, recipient-site adverse events occurred in 56 patients (46.7%), and recipient-site surgical site infections occurred in 45 patients (37.5%). Skeletal muscle index was significantly associated with recipient-site adverse events in univariate analysis (P < 0.05). Lower body mass index and skeletal muscle index were significantly associated with recipient-site surgical site infection in univariate analysis (P < 0.05). In the multiple logistic regression model, a lower skeletal muscle index was a significant risk factor for recipient-site adverse events and surgical site infections (adverse events odds ratio; 3.17/P = 0.04; surgical site infection odds ratio; 3.76/P = 0.02).

Conclusions: The SMI at level Th12 was an independent factor for postoperative AEs, especially SSI, in OSCC patients with free-flap reconstruction.

背景:肌肉疏松症的特征是骨骼肌质量和力量的进行性和普遍性丧失。这项回顾性研究旨在探讨骨骼肌质量对口腔癌切除术后缺损游离瓣重建不良事件的影响:在 120 名患者中,56 名患者(46.7%)发生了受体部位不良事件,45 名患者(37.5%)发生了受体部位手术感染。在单变量分析中,骨骼肌指数与受体部位不良事件有显著相关性(P 结论:骨骼肌指数与受体部位不良事件有显著相关性:在采用游离皮瓣重建的 OSCC 患者中,Th12 水平的骨骼肌指数是导致术后 AE(尤其是 SSI)的独立因素。
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引用次数: 0
Enhanced revision rhinoplasty with processed costal cartilage guided by preoperative computed tomography and 3D scanning 在术前计算机断层扫描和三维扫描的引导下,使用处理过的肋软骨进行强化翻修鼻整形术
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-28 DOI: 10.1186/s40902-024-00422-z
Pawel Szychta
Revision rhinoplasty presents unique challenges, particularly in achieving structural integrity and aesthetic harmony. This study explores the efficacy of costal grafts in addressing these challenges, focusing on anatomical corrections and patient outcomes. A prospective analysis was conducted on patients undergoing revision rhinoplasty with costal grafts. An algorithmic approach was applied to tailor the surgical technique to individual anatomical needs, documented through pre- and postoperative assessments, including CT imaging and 3D scanning. A total of 34 patients were included. Significant improvements were noted in nasal structure and function post-surgery. The mean NOSE score improved from 94.47 ± 5.48 preoperatively to 12.59 ± 13.43 postoperatively, and the mean ROE score increased from 18.44 ± 10.02 to 92.65 ± 13.00, indicating substantial enhancement in both nasal airway function and patient satisfaction. The use of costal grafts facilitated effective corrections for a broad spectrum of nasal deformities, with a complication rate of 2.94%. Costal grafts in revision rhinoplasty offer a versatile and effective solution for complex nasal deformities. The algorithmic approach used in this study enhances repeatability and outcomes, suggesting a promising avenue for achieving desired aesthetic and functional results in revision cases. Further research is warranted to optimize techniques and evaluate long-term outcomes. II.
翻修鼻整形术面临着独特的挑战,尤其是在实现结构完整性和美学和谐方面。本研究探讨了肋骨移植在应对这些挑战方面的功效,重点关注解剖矫正和患者效果。研究对接受肋骨移植修复鼻整形术的患者进行了前瞻性分析。通过术前和术后评估(包括 CT 成像和 3D 扫描)记录,采用算法方法根据个人解剖学需求定制手术技术。共纳入了 34 名患者。术后鼻腔结构和功能均有显著改善。平均 NOSE 分数从术前的 94.47 ± 5.48 分提高到术后的 12.59 ± 13.43 分,平均 ROE 分数从 18.44 ± 10.02 分提高到 92.65 ± 13.00 分,这表明鼻腔气道功能和患者满意度均有大幅提高。使用肋骨移植可有效矫正各种鼻畸形,并发症发生率为 2.94%。翻修鼻整形术中的肋骨移植为复杂的鼻部畸形提供了一种多功能、有效的解决方案。本研究中使用的算法方法提高了可重复性和效果,为在翻修病例中实现理想的美学和功能效果提供了一种可行的途径。为优化技术和评估长期效果,还需要进一步研究。II.
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引用次数: 0
Optimizing precision rhinoplasty: comprehensive preoperative planning with nasal computed tomography for functional and aesthetic enhancement. 优化精准鼻整形术:利用鼻部计算机断层扫描进行全面的术前规划,以增强功能和美感。
IF 2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1186/s40902-024-00423-y
Pawel Szychta

Background: The evolving field of rhinoplasty increasingly recognizes the importance of clinical expertise over routine preoperative nasal computed tomography (CT) for planning surgical interventions. This study evaluates the clinical utility of preoperative nasal CT in enhancing the precision of open structured rhinoplasty, focusing on both functional and aesthetic outcomes without compromising patient safety through unnecessary radiation exposure. The study aimed to assess the impact of preoperative nasal CT on surgical planning and intraoperative maneuvers.

Methods: A prospective cohort study involved patients undergoing open structured rhinoplasty with or without preoperative nasal CT. Participants were divided into a study group, receiving preoperative nasal CT, and a control group, undergoing rhinoplasty without such imaging. Surgical modifications were tailored based on CT findings, with outcomes evaluated through postoperative nasal airflow and aesthetic satisfaction.

Results: The study included 205 patients in the CT group and 514 in the control group, with comparable demographics. The CT group demonstrated significant improvements in nasal breathing and higher aesthetic satisfaction postoperatively, with a notable decrease in the NOSE score and an increase in the ROE score compared to the control group. Minor complications were observed in a small percentage of the CT group, showcasing a nuanced approach to addressing individual anatomical variations.

Conclusions: Preoperative nasal CT in open structured rhinoplasty significantly enhances surgical precision, optimizing functional and aesthetic outcomes. This study underscores the utility of preoperative CT in individualized surgical planning, suggesting its pivotal role in the advancement of rhinoplasty practices. Future research should explore long-term benefits and further validate these findings across diverse populations.

背景:在不断发展的鼻整形领域,人们越来越认识到临床专业知识比常规术前鼻部计算机断层扫描(CT)对规划手术干预的重要性。本研究评估了术前鼻腔 CT 在提高开放式结构鼻整形术精确度方面的临床效用,重点关注功能和美学效果,同时不因不必要的辐射暴露而影响患者安全。研究旨在评估术前鼻腔 CT 对手术规划和术中操作的影响:这项前瞻性队列研究涉及接受开放式结构鼻整形术的患者,无论术前是否使用鼻腔 CT。参与者被分为接受术前鼻腔 CT 的研究组和未接受此类成像的对照组。根据 CT 检查结果对手术进行调整,并通过术后鼻腔气流和美学满意度对结果进行评估:研究包括 205 名 CT 组患者和 514 名对照组患者,两组患者的人口统计学特征相当。与对照组相比,CT 组患者的鼻腔呼吸明显改善,术后美学满意度更高,NOSE 评分明显下降,ROE 评分上升。CT组中有一小部分人出现了轻微并发症,展示了一种针对个体解剖差异的细致入微的方法:结论:开放式结构鼻整形术的术前鼻腔 CT 可显著提高手术精确度,优化功能和美学效果。这项研究强调了术前 CT 在个体化手术规划中的作用,表明它在鼻整形术的发展中起着举足轻重的作用。未来的研究应探索其长期益处,并在不同人群中进一步验证这些发现。
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引用次数: 0
Radiological features of Stafne mandibular bone cavity in panoramic image and cone beam computed tomography 全景图像和锥形束计算机断层扫描中斯塔夫内下颌骨骨腔的放射学特征
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-19 DOI: 10.1186/s40902-024-00415-y
Jangwoo Son, Dong-Jae Lee, Kang-Min Ahn
Stafne mandibular bone cavity (SMBC) is an asymptomatic radiolucent lesion observed in the mandible on X-ray images, with well-defined borders. This lesion does not require treatment, and size changes are very rare. The purpose of this article is to summarize the radiological and clinical features of SMBC, aiming to prevent misinterpretation of this benign lesion as other pathologies and aid in differential diagnosis within the field of dental practice. A total of 32 patients who visited our hospital and were radiologically diagnosed with SMBC based on cone-beam computed tomography (CBCT) and panoramic images between 2005 and 2021 were included in this study. Among them, surgical intervention was performed in one case. Gender and age distribution of the patients, radiographic location and size of the lesion, relationship with the mandibular canal in CBCT, presence of cortical bone erosion in the mandibular lingual area in panoramic images, and the amount of residual cortical bone on the affected side in CBCT were investigated. Patients were 26 men (81.3%) and 6 women, with a mean age of 54.3 years. The average horizontal and vertical length was 16.6 mm and 10.6 mm. Out of a total of 32 cases, 29 cases were found in the posterior region of the mandibular body, while 3 cases were in the angle of the mandible. Lesions located below the mandibular canal were observed in 29 cases, while lesions involving the mandibular canal were present in 3 cases. Erosion of the mandibular lingual cortical bone was observed in 11 cases (34.4%), while 21 cases (65.6%) showed no erosion on panoramic images. Among the total of 14 cases (43.8%) where the cortical bone on the affected side was invaded, the average residual cortical bone thickness was 1.1 mm. SMBC is a benign lesion primarily found in the mandibular angle and posterior body of the mandible. In most cases, treatment is not necessary, and differentiation from other lesions can be achieved by understanding its clinical characteristics and features on panoramic radiographs and CBCT.
下颌骨骨腔(Stafne mandibular bone cavity,SMBC)是一种在 X 射线图像上观察到的无症状放射状病变,边界清晰。这种病变不需要治疗,其大小变化也非常罕见。本文旨在总结 SMBC 的放射学和临床特征,以防止将这种良性病变误诊为其他病变,并帮助牙科临床进行鉴别诊断。本研究共纳入了 2005 年至 2021 年期间到我院就诊并根据锥束计算机断层扫描(CBCT)和全景图像被放射学诊断为 SMBC 的 32 例患者。其中一例患者接受了手术治疗。研究调查了患者的性别和年龄分布、病变的影像学位置和大小、CBCT 与下颌管的关系、全景图像中下颌舌侧皮质骨侵蚀的情况以及 CBCT 中患侧皮质骨的残留量。患者中有 26 名男性(81.3%)和 6 名女性,平均年龄为 54.3 岁。横向和纵向平均长度分别为 16.6 毫米和 10.6 毫米。在32例病例中,29例位于下颌骨体后部,3例位于下颌角。29例病变位于下颌骨管下方,3例病变涉及下颌骨管。11 例(34.4%)观察到下颌骨舌侧皮质骨侵蚀,21 例(65.6%)在全景图像上未显示侵蚀。在总共 14 例(43.8%)患侧皮质骨被侵蚀的病例中,平均残余皮质骨厚度为 1.1 毫米。SMBC是一种良性病变,主要发生在下颌角和下颌体后部。在大多数情况下,无需进行治疗,只要了解其临床特点以及全景X光片和CBCT的特征,就可以将其与其他病变区分开来。
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引用次数: 0
Prognostic factors of oral squamous cell carcinoma: the importance of recurrence and pTNM stage. 口腔鳞状细胞癌的预后因素:复发和 pTNM 分期的重要性。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-04 DOI: 10.1186/s40902-024-00410-3
Min Jae Kim, Kang-Min Ahn

Background: Oral squamous cell carcinoma has a poor prognosis. Therefore, prognostic factors are important to increase the survival rate. This study assessed the survival rate and the prognostic factors for survival of patients with oral squamous cell carcinoma.

Method: This study included 168 patients who underwent surgery for oral squamous cell carcinoma between January 2006 and December 2021. The survival rate was analyzed with overall survival and disease-specific survival. The patient's age, sex, pTNM stage, primary sites (lip, tongue, mouth of floor, mandibular gingiva, maxillary gingiva, mandibular vestibule, maxillary vestibule, retromolar trigone, palate, buccal mucosa, primary intra-osseous site), smoking and alcohol drinking habits, depth of invasion, perineural and lymphovascular invasion, cell differentiation, and postoperative radiotherapy were evaluated to analyze risk factors. Kaplan-Meier methods were used to estimate the survival rates. Cox regression methods were used to investigate the main independent predictors of survival in univariable and multivariable analysis.

Results: Sixty-eight patients died of oral squamous cell carcinoma during follow-up periods. Their overall survival for 5 years was 51.2%, and the disease-specific survival was 59.2%. In univariable analysis, seven factors which are neck metastasis, depth of invasion, cell differentiation, lymphovascular invasion, postoperative radiotherapy, pTNM stage, and recurrence were significantly associated with survival. In multivariable analysis, pTNM stage and recurrence were significantly associated with survival.

Conclusion: In patients with oral squamous cell carcinoma, pTNM stage and recurrence were significant prognostic factors. Neck metastasis, depth of invasion, cell differentiation, lymphovascular invasion, and postoperative radiotherapy were also prognostic factors. These factors serve as markers for obtaining prognosis information in oral squamous cell carcinoma.

背景介绍口腔鳞状细胞癌预后较差。因此,预后因素对提高生存率非常重要。本研究评估了口腔鳞状细胞癌患者的生存率和预后因素:本研究纳入了 2006 年 1 月至 2021 年 12 月期间接受口腔鳞状细胞癌手术的 168 例患者。生存率分析包括总生存率和疾病特异性生存率。对患者的年龄、性别、pTNM分期、原发部位(唇、舌、口底、下颌龈、上颌龈、下颌前庭、上颌前庭、三叉神经后突、腭、颊粘膜、原发骨内部位)、吸烟和饮酒习惯、侵犯深度、神经周围和淋巴管侵犯、细胞分化和术后放疗进行了评估,以分析风险因素。采用 Kaplan-Meier 方法估算生存率。在单变量和多变量分析中,采用Cox回归法研究生存率的主要独立预测因素:结果:68名患者在随访期间死于口腔鳞状细胞癌。结果:68名患者在随访期间死亡,5年总生存率为51.2%,疾病特异性生存率为59.2%。在单变量分析中,颈部转移、侵犯深度、细胞分化、淋巴管侵犯、术后放疗、pTNM分期和复发这7个因素与生存率显著相关。在多变量分析中,pTNM分期和复发与生存率显著相关:结论:在口腔鳞状细胞癌患者中,pTNM分期和复发是重要的预后因素。颈部转移、侵犯深度、细胞分化、淋巴管侵犯和术后放疗也是预后因素。这些因素可作为获取口腔鳞状细胞癌预后信息的标记。
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引用次数: 0
Residual calcified material volume of β-tricalcium phosphate with platelet-rich fibrin in unilateral alveolar bone graft. 单侧牙槽骨移植中含有富血小板纤维蛋白的β-磷酸三钙的残余钙化物体积。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-01 DOI: 10.1186/s40902-024-00420-1
Chon T Ho Nguyen, Minh H Bui, Phuong H Lam

Background: This study aimed to evaluate the effectiveness of β-tricalcium phosphate (β-TCP) and platelet-rich fibrin (PRF) in unilateral alveolar bone graft, involving the percentage of residual calcified material and the average labiopalatal thickness of the grafts on cone beam computed tomography at 6 months after surgery, comparing two age groups 12 years and under and over 12 years old.

Results: The mean preoperative defect volume was 0.93 ± 0.20 cm3, with no significant difference between the two groups (p = 0.652). In the postoperative period, we did not record any abnormal bleeding and no infection was observed. Six months after surgery, the mean percentage of residual calcified material was 63.53 ± 16.48% with a significantly higher difference in the age group 12 and under (p < 0.001), and the mean average labiopalatal thickness of the grafted bone was 5.72 ± 1.09 mm with a significantly higher difference in the age group 12 and under (p = 0.011).

Conclusion: Using β-TCP and PRF in alveolar bone graft surgery has acceptable effectiveness clinically and on CBCT images, with significantly higher differences of the percentage of residual calcified material and the average labiopalatal thickness of the grafted bone in the group 12 years old and younger than in the older group.

背景:该研究旨在评估β-磷酸三钙(β-TCP)和富血小板纤维蛋白(PRF)在单侧牙槽骨移植中的有效性,涉及术后6个月锥形束计算机断层扫描中残留钙化材料的百分比和移植体的平均唇缘厚度,并对12岁及以下和12岁以上两个年龄组进行了比较:术前平均缺损体积为 0.93 ± 0.20 cm3,两组间无显著差异(p = 0.652)。术后未发现异常出血和感染。术后六个月,残留钙化物的平均百分比为(63.53 ± 16.48)%,12 岁及以下组的差异显著较高(p < 0.001),移植骨的平均唇缘厚度为(5.72 ± 1.09)mm,12 岁及以下组的差异显著较高(p = 0.011):结论:在牙槽骨移植手术中使用β-TCP和PRF在临床上和CBCT图像上都具有可接受的效果,12岁及以下组的残余钙化材料百分比和移植骨平均唇缘厚度的差异明显高于年龄较大组。
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引用次数: 0
Outcomes of treatment with short dental implants compared with standard-length implants: a retrospective clinical study. 短牙种植体与标准长度种植体的治疗效果比较:一项回顾性临床研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-28 DOI: 10.1186/s40902-024-00419-8
Kinga Bérczy, György Göndöcs, György Komlós, Tatiana Shkolnik, György Szabó, Zsolt Németh

Background: The size of dental implants is a key success factor for appropriate osseointegration. Using shorter implants allows the possibility of avoiding complex surgical procedures and reduces the morbidity of treatment. Shorter implants also enable implant-prosthetic rehabilitation after maxillofacial reconstructions where only limited bone is available. In this study, the success rates of short implants were examined and compared to those of standard-sized implants.

Methods: Patients who received dental implants between 2007 and 2016 at the Department of Oro-Maxillofacial Surgery and Stomatology Semmelweis University were enrolled in the study. Several clinical parameters were recorded and supplemented with radiological examinations. The data were statistically analysed.

Results: Thirty-four patients with a total of 60 implants were included. The average time after prosthetic loading was 39.33 ± 21.96 months in the group with 8-mm implants and 41.6 ± 27.5 months in the group with > 8-mm implants. No significant differences were observed between the two groups in terms of probing depth (short implants, 2.84 ± 0.09 mm; standard implants, 2.91 ± 0.35 mm) or mean marginal bone loss (short implants, 1.2 ± 1.21-mm mesially and 1.36 ± 1.47-mm distally; standard implants: 0.63 ± 0.80-mm mesially and 0.78 ± 0.70-mm distally).

Conclusions: In this study, the success rate of short dental implants was comparable to that of standard-sized implants. Consequently, it can be claimed that the long-term success of short dental implants does not differ significantly from the long-term success of standard implants.

背景:牙科植入物的大小是适当骨结合的关键因素。使用较短的种植体可以避免复杂的外科手术,降低治疗的发病率。较短的种植体还能在骨量有限的颌面部重建后实现种植修复。在这项研究中,我们对短型种植体的成功率进行了研究,并与标准尺寸种植体的成功率进行了比较:研究对象为 2007 年至 2016 年期间在塞梅尔维斯大学颌面外科和口腔医学系接受牙科植入物治疗的患者。研究人员记录了多项临床参数,并辅以放射学检查。对数据进行了统计分析:结果:34名患者共植入了60颗种植体。植入 8 毫米种植体的患者平均修复时间为 39.33 ± 21.96 个月,植入大于 8 毫米种植体的患者平均修复时间为 41.6 ± 27.5 个月。两组在探查深度(短种植体,2.84 ± 0.09 mm;标准种植体,2.91 ± 0.35 mm)或平均边缘骨质流失(短种植体,中线 1.2 ± 1.21 mm,远线 1.36 ± 1.47 mm;标准种植体,0.63 ± 0.80 mm)方面无明显差异:结论:在这项研究中,短牙种植体的成功率与标准尺寸种植体的成功率相当。因此,可以说短牙种植体的长期成功率与标准种植体的长期成功率没有显著差异。
{"title":"Outcomes of treatment with short dental implants compared with standard-length implants: a retrospective clinical study.","authors":"Kinga Bérczy, György Göndöcs, György Komlós, Tatiana Shkolnik, György Szabó, Zsolt Németh","doi":"10.1186/s40902-024-00419-8","DOIUrl":"10.1186/s40902-024-00419-8","url":null,"abstract":"<p><strong>Background: </strong>The size of dental implants is a key success factor for appropriate osseointegration. Using shorter implants allows the possibility of avoiding complex surgical procedures and reduces the morbidity of treatment. Shorter implants also enable implant-prosthetic rehabilitation after maxillofacial reconstructions where only limited bone is available. In this study, the success rates of short implants were examined and compared to those of standard-sized implants.</p><p><strong>Methods: </strong>Patients who received dental implants between 2007 and 2016 at the Department of Oro-Maxillofacial Surgery and Stomatology Semmelweis University were enrolled in the study. Several clinical parameters were recorded and supplemented with radiological examinations. The data were statistically analysed.</p><p><strong>Results: </strong>Thirty-four patients with a total of 60 implants were included. The average time after prosthetic loading was 39.33 ± 21.96 months in the group with 8-mm implants and 41.6 ± 27.5 months in the group with > 8-mm implants. No significant differences were observed between the two groups in terms of probing depth (short implants, 2.84 ± 0.09 mm; standard implants, 2.91 ± 0.35 mm) or mean marginal bone loss (short implants, 1.2 ± 1.21-mm mesially and 1.36 ± 1.47-mm distally; standard implants: 0.63 ± 0.80-mm mesially and 0.78 ± 0.70-mm distally).</p><p><strong>Conclusions: </strong>In this study, the success rate of short dental implants was comparable to that of standard-sized implants. Consequently, it can be claimed that the long-term success of short dental implants does not differ significantly from the long-term success of standard implants.</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":"46 1","pages":"6"},"PeriodicalIF":2.3,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10902233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139983296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Maxillofacial Plastic and Reconstructive Surgery
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