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Analysis of the sleep period and the amount of habitual snoring in individuals with sleep bruxism 睡眠磨牙症患者睡眠时间及习惯性打鼾次数分析
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23136
M. Palinkas, Julio Marrara, C. Bataglion, J. Hallak, G. Canto, P. H. Scalize, I. Regalo, S. Siéssere, S. Regalo
Background The literature does not report any association between habitual snoring and sleep bruxism, but these situations can be a reason for frequent complaints of individuals, impairing the quality of life. This study was performed to investigate the sleep period and amount of habitual snoring in individuals with sleep bruxism observing expiratory, inspiratory, and mixed snoring. Material and Methods A total of 90 individuals were screened and divided into the following groups: with sleep bruxism (n=45) and those without sleep bruxism (n=45). Single night sleep polysomnography was performed to diagnose sleep bruxism, quantify habitual snoring and sleep period. The results were tabulated and submitted to a Multivariate analysis of variance (MANOVA) to compare the means of the two independent groups, considering the affected diagnosis of sleep bruxism, snoring (independent variables) and age as covariate. For the post hoc, was used correcting for multiple comparisons (Bonferroni test, P <.05). Results There was statistically significant difference among the groups ( p =.001) in the sleep period, in that individuals with sleep bruxism slept for a longer duration (with sleep bruxism group: 460 minutes and without sleep bruxism group: 401 minutes). There were no statistically significant differences among the groups for the number of inspiratory, expiratory and mixed snores, but was observed greater amount of snoring in the with sleep bruxism group. Conclusions The main finding of this study is that individuals with sleep bruxism slept longer than the control group. It may also be suggested that individuals with sleep bruxism tended to increase the amount of habitual snoring during sleep. Key words:Bruxism, adult, sleep disordered breathing, polysomnography.
文献没有报道习惯性打鼾和睡眠磨牙症之间的任何联系,但这些情况可能是个人经常抱怨的原因,损害了生活质量。本研究旨在探讨睡眠磨牙症患者的睡眠时间和习惯性打鼾的数量,观察呼气、吸气和混合性打鼾。材料与方法筛选90例睡眠磨牙患者,分为有睡眠磨牙患者组(n=45)和无睡眠磨牙患者组(n=45)。采用单夜睡眠多导睡眠图诊断磨牙症,量化习惯性打鼾和睡眠时间。考虑到睡眠磨牙、打鼾(自变量)和年龄作为协变量的影响诊断,将结果制成表格并提交多变量方差分析(Multivariate analysis of variance, MANOVA)来比较两个独立组的均值。对于事后比较,采用多重比较校正(Bonferroni检验,P < 0.05)。结果两组睡眠时间差异有统计学意义(p = 0.001),睡眠磨牙组睡眠时间更长(有睡眠磨牙组460分钟,无睡眠磨牙组401分钟)。两组间吸气式、呼气式及混合性打鼾次数差异无统计学意义,但有磨牙症组打鼾次数较多。结论本研究的主要发现是睡眠磨牙症患者的睡眠时间比对照组长。这也可能表明,患有睡眠磨牙症的人往往会在睡眠中增加习惯性打鼾的次数。关键词:磨牙症;成人;睡眠呼吸障碍;
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引用次数: 7
Detection of periodontal pathogens in mothers of preterm birth and/or low weight 对早产和/或体重过轻母亲牙周病原体的检测
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23135
Nayra Rodrigues de Vasconcelos Calixto, C. Alves, Luciene Maria Gomes Abreu, É. Thomaz, F. Vidal, Isaac Suzart Filho, F. Lopes
Background The present study aims to estimate the possible relationship between periodontal pathogens in the oral cavity and the birth of Preterm Birth (PTB) and/or Low Birth Weight (LBW). Material and Methods It’s a case- control study with the subgengival biofilm samples were collected from four sites up deeper until 48 hours postpartum and were processes by Polymerase Chain Reaction (PCR) for presence the periodontal pathogens Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn), Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf) e Aggregatibacter actinomycetemcomitans (Aa). The mothers were divided into case grup (babies weighing < 2500g and/or gestational age < 37 weeks) and control group (babies weighing ≥ 2500g and gestational age ≥ 37 weeks). Chi-square test and the measure of association obtained by Odds Ratio (OR) were used to estimate the association between the variables. Results Microbial analyses results showed no significant association between PTB and LBW with most periodontal pathogens in the oral cavity, even with association with the clinical presence of periodontitis. Conclusions given the high presence of periodontal pathogens in the biofilm subgengival of recent mothers, it is suggested that the findings of this research serve as the basis for future studies on the pathophysiology involved in the relationship between periodontitis and PTB and/or LBW. Key words:Low Birth Weight Infant. Premature Infant. Periodontal Diseases. Bacteria. Polymerase Chain Reaction.
本研究旨在评估口腔内牙周病原体与早产(PTB)和/或低出生体重(LBW)之间的可能关系。材料与方法采用病例对照研究方法,在产后48小时内采集4个部位的龈下生物膜标本,采用聚合酶链反应(PCR)检测牙周病原菌中间普氏菌(Pi)、核梭菌(Fn)、牙龈卟啉单胞菌(Pg)、齿状密螺旋体(Td)、连翘Tannerella (Tf)、放线菌comitans (Aa)。将母亲分为病例组(婴儿体重< 2500g和/或胎龄< 37周)和对照组(婴儿体重≥2500g和胎龄≥37周)。采用卡方检验和比值比(Odds Ratio, OR)获得的相关性度量来估计变量之间的相关性。结果微生物学分析结果显示,PTB和LBW与口腔内大多数牙周病原体无显著相关性,甚至与牙周炎的临床表现有关。结论:鉴于新近出生的母亲的牙龈下生物膜中存在大量牙周病原体,本研究结果可为进一步研究牙周炎与PTB和/或LBW之间的病理生理学关系奠定基础。关键词:低出生体重儿;早产儿。牙周疾病。细菌。聚合酶链反应。
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引用次数: 8
Chronic ulcerative stomatitis: A systematic review of the clinical and microscopic features 慢性溃疡性口炎:临床和显微特征的系统回顾
Pub Date : 2019-10-27 DOI: 10.4317/medoral.22213
T. M. Ferrisse, Daphine Caxias Travassos, A. F. L. Rocha, E. Massucato, A. Bufalino
Background the purpose of this study was to perform a systematic review regarding clinical and histopathological characteristics, immunopathological findings, and treatment for chronic ulcerative stomatitis (CUS). Material and Methods articles in English, published from January 1962 up to November 2017, assessing clinical and immunological features, treatment, and follow-up of patientes with CUS, were retrieved from three databases (PubMed, Cochrane Library and SCOPUS). A manual literature search was also conducted. A total of 12 studies met inclusion criteria, therefore, were analyzed in this review. Results CUS shares similiar clinical and microscopic features to those found in oral lichen planus (OLP) and oral lichenoid lesions (OLL). Hence, direct immunofluorescence (DIF) is indispensable to define a final diagnosis. Due to the poor sample availability in the current literature, it is not possible to accurately confirm the prevalence and features of CUS. Conclusions in order to better evaluate this condition’s findings, further studies with a greater amount of similar immune-mediated diseases should be performed. Key words:Chronic ulcerative stomatitis, immune-mediated diseases, immunofluorescence, lichen planus.
背景:本研究的目的是对慢性溃疡性口炎(CUS)的临床和组织病理学特征、免疫病理结果和治疗进行系统回顾。材料和方法从三个数据库(PubMed、Cochrane Library和SCOPUS)中检索1962年1月至2017年11月发表的英文文章,评估CUS患者的临床和免疫学特征、治疗和随访。还进行了手工文献检索。因此,本综述共分析了12项符合纳入标准的研究。结果CUS与口腔扁平苔藓(OLP)和口腔苔藓样病变(OLL)具有相似的临床和显微特征。因此,直接免疫荧光(DIF)对于确定最终诊断是必不可少的。由于目前文献中样本可用性差,无法准确确认CUS的患病率和特征。结论:为了更好地评估这种情况的发现,应该进行更多类似免疫介导疾病的进一步研究。关键词:慢性溃疡性口炎;免疫介导性疾病;免疫荧光;
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引用次数: 4
Clinical patterns and characteristics of midfacial fractures in western romanian population: a 10-year retrospective study 罗马尼亚西部人群面中骨折的临床模式和特征:一项10年回顾性研究
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23153
P. Tent, R. Juncar, M. Juncar
Background The aim of this study was to identify the clinical pattern of midfacial fractures and concomitant associated injuries in our geographical area, as well as to correlate them in order to determine the type of fracture with the highest incidence of associated injuries. Material and Methods A 10-year retrospective evaluation of midfacial fractures was performed in 379 patients. Results Zygomatic complex fractures had the highest incidence (n=242, 50%). The majority of the fractures were complete (n=561, 92.42%), closed (n=473, 84.16%) and without displacement (n=454, 80.78%) regardless of the location of the fracture line (p=0.014). All patients had at least one associated soft tissue injury (n=379, 100%). The most frequent associated injury was hematoma (n=308, 73.51%). Hematomas were predominant in the case of single fractures, while lacerations and excoriations were prevalent in the case of multiple fractures (p=0.000). Conclusions Following trauma of the midface, patients with soft tissue hematomas will most probably have an underlying fracture with a single trajectory, while patients with lacerations will most probably have concomitant multiple bone fractures. Key words:Midface, fracture, trauma, pattern, associated injuries.
本研究的目的是确定在我们的地理区域面中部骨折和伴随相关损伤的临床模式,并将它们联系起来,以确定伴随损伤发生率最高的骨折类型。材料与方法对379例面中骨折患者进行10年回顾性分析。结果颧骨复合体骨折发生率最高(242.50%)。与骨折线位置无关(p=0.014),大多数骨折为完整骨折(n=561, 92.42%)、闭合骨折(n=473, 84.16%)和无移位骨折(n=454, 80.78%)。所有患者至少有一个相关的软组织损伤(n= 379,100%)。最常见的相关损伤是血肿(n=308, 73.51%)。单发骨折以血肿为主,多发骨折以撕裂伤和擦伤为主(p=0.000)。结论中面部外伤后,软组织血肿患者最可能并发单一轨迹的潜在骨折,而撕裂伤患者最可能并发多发性骨折。关键词:中面部;骨折;创伤;
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引用次数: 8
Effect of preemptive dexamethasone and etoricoxib on postoperative period following impacted third molar surgery - a randomized clinical trial 地塞米松和依托瑞昔布对阻生第三磨牙手术术后时间的影响——一项随机临床试验
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23095
É. Rodrigues, Gabriela Soares Pereira, B. Vasconcelos, R. D. C. Ribeiro
Background The aim of this study was to compare the anti-inflammatory effects of dexamethasone and etoricoxib after third molar extraction. Material and Methods A prospective, randomized, controlled, split-mouth study was conducted. 19 volunteers were allocated randomly to receive 90mg etoricoxib 1 hour prior to the procedure or 4mg intramuscular dexamethasone immediately after anesthesia. Baseline measurements were obtained preoperatively, and subsequent assessments were made on immediate postoperative, at 72 hours and 7 days after surgery to measure postoperative facial swelling by use of linear measurements, interincisal mouth opening width and visual analog scale score for pain. The amount of analgesics consumed was recorded. Descriptive statistics and the independent-samples t-test were used to compare the two groups at P < 0.05. Results Dexamethasone was effective in the control roasted edema for measurements of the mandibular angle - wing of the nose and mandibular angle - labial commissure 72 hours after surgery. And for the measurement mandibular angle - mentum, in the time of 72 hours and 7 days. There was no statistically significant difference in relation to pain and trismus. Conclusions Considering significant results for some measures of the variable edema for the group that used intramuscular dexamethasone and the difference without statistical significance between groups for the other variables studied, we seem to reflect the intramuscular indication of the corticosteroid in a single dosage in relation to the use of etoricoxib as pre-emptive medication. Key words:Corticosteroids, COX-2 selective, third-molar surgery.
本研究的目的是比较地塞米松和依托昔布在第三磨牙拔牙后的抗炎作用。材料与方法采用前瞻性、随机对照、裂口法研究。19名志愿者被随机分配,在手术前1小时接受90mg依托瑞昔布,麻醉后立即接受4mg肌注地塞米松。术前进行基线测量,术后即刻、术后72小时和术后7天进行后续评估,使用线性测量、内切口张开宽度和视觉模拟疼痛评分来测量术后面部肿胀。记录镇痛药的用量。两组比较采用描述性统计和独立样本t检验,P < 0.05。结果地塞米松对术后72 h的下颌角-鼻翼和下颌角-唇连度测量均有较好的控制作用。并在72小时和7天的时间内测量下颌角动量。两组在疼痛和牙关咬合方面无统计学差异。考虑到肌注地塞米松组的一些变量水肿测量结果显著,而其他变量研究组间差异无统计学意义,我们似乎反映了单剂量皮质类固醇的肌注适应证与使用依托昔布作为预防性用药的关系。关键词:皮质类固醇,COX-2选择性,第三磨牙手术。
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引用次数: 8
Evaluation the oral hygiene conditions, oral Candida colonization and salivary Streptococcus mutans and Lactobacilli density in a group of β-thalassemic children and adolescence β-地中海贫血儿童及青少年口腔卫生状况、口腔念珠菌定植、唾液变形链球菌及乳酸杆菌密度评价
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23024
H. Karayılmaz, Hande Yalçin-Erman, Özge Erken-Güngör, Z. Öztürk, R. Felek, A. Küpesiz
Background In this study, the prevalence and distribution of dental caries and oral hygiene conditions in a group of patients with β-TM are evaluated and the results compared to age-and gender-matched healthy patients. In addition, oral candida colonization and the density of Streptococcus mutans (S.mutans) and Lactobacilli in the total saliva are assessed. Material and Methods This study involved 59 β-TM patients between 6-16 years old (mean:11.59±3.22), who applied to the Department of Pedodontics, Faculty of Dentistry, Akdeniz University, with ongoing follow-up, treatment and regular blood transfusions. All enrolled patients were diagnosed with β-TM by the Department of Pediatric Hematology and Oncology, Faculty of Medicine, Akdeniz University. As a control group, age-and gender-matched healthy 50 patients were included to the study. Results Plaque (p=0.001), DMFT (p=0.009) and DMFS (p=0.039) indices were significantly higher in the β-TM patients, whereas, the oral hygiene status was significantly lower (p=0.004). Saliva buffering capacity average was insignificantly but slightly more in β-TM patients(p=0.131). While S.mutans values were significantly higher in the β-TM patients (p=0.002), no significant difference was found in the Lactobacillus (p=0.131) and Candida values (p=0.33). Conclusions: DMFT, DMFS, Plaque and oral hygiene indices and S.mutans values were found significantly different in β-TM patients than healthy, control group patients, in this study. Key words:Thalassemia major, DMFT, S.mutans, Lactobacilli, Candida.
本研究评估了一组β-TM患者的龋病患病率和分布以及口腔卫生状况,并将结果与年龄和性别匹配的健康患者进行了比较。此外,评估口腔念珠菌定植以及总唾液中变形链球菌(s.a mutans)和乳酸杆菌的密度。材料与方法本研究纳入59例6-16岁的β-TM患者(平均11.59±3.22),这些患者申请了Akdeniz大学牙科学院的儿科学部门,进行了持续的随访,治疗和定期输血。所有入组患者均由阿克德尼兹大学医学院儿科血液学和肿瘤科诊断为β-TM。作为对照组,50名年龄和性别匹配的健康患者被纳入研究。结果β-TM患者的牙菌斑(p=0.001)、DMFT (p=0.009)和DMFS (p=0.039)指标均显著增高,口腔卫生状况显著降低(p=0.004)。β-TM患者的平均唾液缓冲能力差异不显著,但略高于对照组(p=0.131)。β-TM患者中S.mutans值显著升高(p=0.002),而乳酸菌(p=0.131)和念珠菌(p=0.33)的值无显著差异。结论:β-TM患者的DMFT、DMFS、牙菌斑和口腔卫生指标及s.t amans值与健康对照组相比存在显著差异。关键词:重度地中海贫血,DMFT,变形链球菌,乳酸杆菌,念珠菌
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引用次数: 3
Attitudes of dental implantologists in Spain to prescribing antibiotics, analgesics and anti-inflammatories in healthy patients 西班牙牙种植医师对健康患者开抗生素、镇痛药和抗炎药的态度
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23103
F. Camacho-Alonso, D. Muñoz-Cámara, M. Sánchez‐Siles
Background The implantologists frequently prescribe antibiotics, analgesics and anti-inflammatories in dental implant surgery. The aims of this study were to evaluate the attitudes of implantologists in Murcia (Spain) to prescribing antibiotics, analgesics and anti-inflammatories in healthy patients during different implant dentistry procedures, and to see how these are influenced by individual dentist’s academic level, professional experience, and ongoing training (attending courses or reading scientific literature on medication use) Material and Methods This cross-sectional study included a total of 200 implantologists from the Murcia area (Spain), who each completed a two-page questionnaire consisting of 26 questions. Results The implant procedure in which most dentists (n=97) prescribed antibiotics was multiple implant surgery with flap raising, in which 55.6% of these 97 respondents used a prophylactic antibiotic regime for 7 days after implant placement. All subjects (n=200) prescribed analgesics for eight out of the eleven procedures included in the survey and anti-inflammatories in six. Dentists with higher academic levels or longer professional experience prescribed more antibiotics, but those who underwent continuous training (attending courses or reading scientific literature) reduced antibiotic prescription. Conclusions Dentists often prescribed antibiotics, analgesics and anti-inflammatories in almost all implant procedures in healthy patients, but ongoing training reduced the frequency of antibiotic prescription in some procedures. Key words:Antibiotics, analgesics, anti-inflammatories, dental implant, oral surgery.
背景种植医师在种植牙手术中经常使用抗生素、镇痛药和抗炎药。本研究的目的是评估穆尔西亚(西班牙)的种植医生在不同的种植牙科手术中对健康患者开抗生素、镇痛药和抗炎药的态度,并了解这些是如何受到个体牙医的学术水平、专业经验、材料和方法本横断面研究包括来自穆尔西亚地区(西班牙)的200名种植学家,他们每人完成一份两页的问卷,包含26个问题。结果97名牙科医生使用抗生素最多的种植方式是带皮瓣抬高的多种植体手术,其中55.6%的人在种植体放置后7天内使用预防性抗生素。所有受试者(n=200)在调查中包括的11项手术中有8项使用止痛药,6项使用消炎药。学术水平较高或专业经验较长的牙医会开出更多的抗生素处方,而那些接受过持续培训(参加课程或阅读科学文献)的牙医则会减少抗生素处方。结论牙科医生在健康患者的种植过程中经常使用抗生素、镇痛药和抗炎药,但持续的培训减少了某些手术中抗生素的使用频率。关键词:抗生素,镇痛药,抗炎药,种植牙,口腔外科。
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引用次数: 7
Oral leukoplakia; a proposal for simplification and consistency of the clinical classification and terminology 口腔白斑;关于简化和一致临床分类和术语的建议
Pub Date : 2019-10-27 DOI: 10.4317/medoral.23372
I. van der Waal
There is a distinct lack of uniformity in the definitions and clinical terminologies related to oral leukoplakia and leukoplakialike lesions and disorders. Proposals have been put forward to subclassify leukoplakia into a homogeneous and a non-homogeneous type based on color only, being either predominantly white or mixed white-and-red, respectively, irrespective of the texture of the lesion. In this proposal there is no need anymore to regard the poorly defined proliferative verrucous leukoplakia as a separate entity. Since keratosis is primarily a histopathological term, its clinical use is discouraged. Alternative terminology for these so-called keratotic lesions and disorders has been put forward. Finally, a suggestion has been made to rename the term hairy leukoplakia, being a well defined, not potentially malignant disorder particularly related to HIV-infection, into 'EBV-positive white lesion of the tongue' (EBVposWLT). Key words:Potentially malignant oral disorders, oral leukoplakia, oral keratosis, hairy leukoplakia.
口腔白斑和类似白斑的病变和疾病的定义和临床术语明显缺乏一致性。有人建议仅根据颜色将白斑再分类为均匀型和非均匀型,分别以白色为主或白色和红色混合,而不考虑病变的质地。在本建议中,不再需要将定义不清的增殖性疣状白斑视为一个单独的实体。由于角化病主要是一个组织病理学术语,因此不鼓励临床使用。这些所谓的角化病变和疾病的替代术语已经提出。最后,有人建议将“毛状白斑”一词重新命名为“舌上ebv阳性白色病变”(EBVposWLT),因为毛状白斑是一种定义明确、与hiv感染特别相关的非潜在恶性疾病。关键词:口腔潜在恶性疾病,口腔白斑,口腔角化病,毛状白斑。
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引用次数: 14
Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial 以焦磷酸盐为基础的漱口水抑制龈上牙石形成的能力评估。一项随机双盲安慰剂对照临床试验
Pub Date : 2019-08-19 DOI: 10.4317/medoral.23036
Carla Fons-Badal, R. Agustín-Panadero, M. Solá-Ruíz, F. Alpiste-Illueca, Antonio Font-Fons
Background This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. Material and Methods This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients’ subjective perceptive of mouth rinse efficacy. Results The test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective. Conclusions The test/B and placebo mouth rinses both modified certain parameters in saliva composition, particularly reductions in urea, uric acid, and phosphorous. Calcium tended to increase after using the test-B mouth rinse. The results did not demonstrate the anticalculus efficacy of the pyrophosphate-based mouth rinse or positive effects on saliva flow or composition. This field requires further research, as no product has been developed that prevents calculus formation completely. Key words:Dental calculus, anticalculus mouth rinse, Volpe Manhold index.
本研究旨在分析一种抗牙石漱口水的疗效及其对粘膜和牙齿可能产生的不良影响。材料与方法本随机双盲安慰剂对照临床试验纳入40例牙周病患者,均有牙石快速形成史。患者使用基于焦磷酸盐的测试漱口水(B)或安慰剂(a)。测量一系列参数:唾液(唾液流量、pH值和化学成分);微积分(Volpe-Manhold [V-M]指数、权重和体积);对黏膜及牙齿的不良影响;以及患者对漱口水疗效的主观感知。结果试验漱口水B使尿素、尿酸、磷、钙、唾液流量降低,ph - V-M指数升高,结石重量降低。两种漱口剂均可减少牙石体积。未观察到粘膜和牙齿的变化。患者认为测试漱口水更有效。结论:试验/B漱口水和安慰剂漱口水都改变了唾液成分的某些参数,特别是尿素、尿酸和磷的减少。使用试验b漱口水后,钙含量有增加的趋势。结果没有证明焦磷酸盐为基础的漱口水的除结石功效或积极影响唾液流动或组成。这一领域还需要进一步的研究,因为目前还没有开发出能够完全防止结石形成的产品。关键词:牙结石,除牙石漱口水,Volpe Manhold指数。
{"title":"Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial","authors":"Carla Fons-Badal, R. Agustín-Panadero, M. Solá-Ruíz, F. Alpiste-Illueca, Antonio Font-Fons","doi":"10.4317/medoral.23036","DOIUrl":"https://doi.org/10.4317/medoral.23036","url":null,"abstract":"Background This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. Material and Methods This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients’ subjective perceptive of mouth rinse efficacy. Results The test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective. Conclusions The test/B and placebo mouth rinses both modified certain parameters in saliva composition, particularly reductions in urea, uric acid, and phosphorous. Calcium tended to increase after using the test-B mouth rinse. The results did not demonstrate the anticalculus efficacy of the pyrophosphate-based mouth rinse or positive effects on saliva flow or composition. This field requires further research, as no product has been developed that prevents calculus formation completely. Key words:Dental calculus, anticalculus mouth rinse, Volpe Manhold index.","PeriodicalId":18367,"journal":{"name":"Medicina Oral, Patología Oral y Cirugía Bucal","volume":"2016 1","pages":"e621 - e629"},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87948508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Is the re-use of sterilized implant abutments safe enough? (Implant abutment safety) 重复使用已消毒的种植体基台是否足够安全?(种植基台安全)
Pub Date : 2019-08-19 DOI: 10.4317/medoral.22967
M. Sánchez-Garcés, Marta Jorba, Joan Ciurana, M. Viñas, M. Vinuesa
Background: The reuse of implant healing abutments is common in dental practice. Effective elimination of bacteria and viruses is accomplished by conventional sterilization. The aim of this work was to explore the eventual survival of microorganisms on sterilized healing abutments and to rule out the presence of transmissible organic material after standard procedures. Material and Methods: A total of 55 healing abutments previously used in patients will be washed and sterilized in a steam autoclave at 121ºC for 15 min. Each healing abutment will be cultured in Brain Heart Infusion broth (BHI) under strict aseptic conditions. Besides, two control groups will be included: one of 3 unused healing abutments, and the other of just medium. After 10 days at 37°C under a 5% CO2 100 µl of the broth will be plated on solid media (Brain Infusion Agar, BHIA) and Columbia Blood agar to test for sterility. The remaining volume will be centrifuged, the sediment fixed, and a Gram stain performed to discard the presence of non-cultivable microorganisms. Moreover, to determine the presence of remaining organic material after the cleaning and sterilizing treatments, the bioburden will be determined by measuring total organic carbon (TOC) in another 10 previously used healing abutments, cleaned and sterilized, that will be submerged in Milli-Q water and sonicated. Results: No bacterial growth was detected on any of the 58 cultured abutments, indicating that the sterilization was completely satisfactory in terms of removal of live bacteria or spores. Nevertheless, significant amounts of organic carbon may still be recovered (up to 125,31 µg/abutment) after they have been sterilized. Conclusions: Significant amounts of the bioburden remained adhered to the surfaces in spite of the cleaning and sterilization procedures. Taking into account our results and data from other authors, the presence of infectious particles on the reused healing abutments such as prions cannot be ruled out. Key words:Healing abutment, abutment surface, peri-implantitis, mucositis, sterilization.
背景:种植体修复基台的重复使用在牙科实践中很常见。细菌和病毒的有效清除是通过传统的灭菌来完成的。这项工作的目的是探索微生物在灭菌愈合基台上的最终存活,并在标准程序后排除可传播的有机物质的存在。材料和方法:将55个先前用于患者的愈合基台在121℃的蒸汽高压灭菌器中清洗并消毒15分钟。每个愈合基台将在严格的无菌条件下在脑心灌注汤(BHI)中培养。另外,将包括两个对照组:一组为3个未使用的愈合基台,另一组为中等。在37°C下5% CO2下10天后,将100µl的肉汤涂于固体培养基(Brain Infusion Agar, BHIA)和Columbia Blood琼脂上进行无菌测试。剩余的体积将被离心,沉积物固定,并进行革兰氏染色,以丢弃不可培养的微生物的存在。此外,为了确定清洁和灭菌处理后剩余有机物质的存在,生物负荷将通过测量另外10个先前使用的愈合基台的总有机碳(TOC)来确定,这些基台将被清洁和灭菌,并将浸入milliq水中并进行超声波处理。结果:58个培养基牙均未检出细菌生长,表明灭菌在去除活菌或孢子方面完全令人满意。然而,大量的有机碳在消毒后仍可被回收(高达125,31µg/基台)。结论:尽管进行了清洁和灭菌程序,但仍有大量的生物负担粘附在表面。考虑到我们的结果和其他作者的数据,不能排除在重复使用的愈合基台上存在感染性颗粒,如朊病毒。关键词:愈合基牙,基牙表面,种植周炎,粘膜炎,灭菌。
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引用次数: 9
期刊
Medicina Oral, Patología Oral y Cirugía Bucal
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