Pub Date : 2020-05-01DOI: 10.31556/2219-0678.2020.39.1.008-018
V. Omelyanovskiy, A. Antonov, T. Bezdenezhnykh, G. Khachatryan
Objective: to analyze clinical studies of drugs used for COVID-19 prevention and treatment and to identify ongoing randomized controlled trials (RCT) of drugs used for COVID-19 prevention and treatment. Methods. A systematic search of completed clinical studies was performed in MedLine database and in reference lists of the articles found. Ongoing RCT were looked for in clinicaltrials.gov; also the search was made in Google Scholar. Result. Drugs that are currently used for COVID-19 were assessed in 18 completed clinical studies of other infections, e.g. other coronaviruses and Ebola virus. 15 completed published studies were devoted to their use for COVID-19. Case series reports where COVID-19 drug therapy is mentioned, are cited as well. 41 RCT of COVID-19 therapy were registered in clinicaltrials.gov. Remdesivir, lopinavir/ritonavir, chloroquine, hydroxychloroquine and favipiravir are studied most often. Still the results of the completed studies cannot justify confidently the recommendation to use any of the drugs for COVID-19 prevention and treatment. Conclusion. Currently there is no clinical evidence to reliably support any of the drug’s efficacy for COVID-19 prevention and treatment. Nevertheless, a lot of RCT are expected to be completed in the nearest future.
{"title":"Current Research Data on Drug Therapy for Novel Coronavirus Associated Disease (COVID-19): Systematic Review","authors":"V. Omelyanovskiy, A. Antonov, T. Bezdenezhnykh, G. Khachatryan","doi":"10.31556/2219-0678.2020.39.1.008-018","DOIUrl":"https://doi.org/10.31556/2219-0678.2020.39.1.008-018","url":null,"abstract":"Objective: to analyze clinical studies of drugs used for COVID-19 prevention and treatment and to identify ongoing randomized controlled trials (RCT) of drugs used for COVID-19 prevention and treatment.\u0000\u0000Methods. A systematic search of completed clinical studies was performed in MedLine database and in reference lists of the articles found. Ongoing RCT were looked for in clinicaltrials.gov; also the search was made in Google Scholar.\u0000\u0000Result. Drugs that are currently used for COVID-19 were assessed in 18 completed clinical studies of other infections, e.g. other coronaviruses and Ebola virus. 15 completed published studies were devoted to their use for COVID-19. Case series reports where COVID-19 drug therapy is mentioned, are cited as well. 41 RCT of COVID-19 therapy were registered in clinicaltrials.gov. Remdesivir, lopinavir/ritonavir, chloroquine, hydroxychloroquine and favipiravir are studied most often. Still the results of the completed studies cannot justify confidently the recommendation to use any of the drugs for COVID-19 prevention and treatment.\u0000\u0000Conclusion. Currently there is no clinical evidence to reliably support any of the drug’s efficacy for COVID-19 prevention and treatment. Nevertheless, a lot of RCT are expected to be completed in the nearest future.","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75144427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-01DOI: 10.31556/2219-0678.2020.39.1.030-042
A. N. Daykhes, V. Reshetnikov, O. Manerova, I. Mikhailov
Aim of the study. Analysis of medical tourism’s organizational features based on the example of the large medical organizations in the United Kingdom, South Korea, Italy and China. Materials and methods. The data were collected by the authors by interviewing the heads of medical organizations and their deputies in the United Kingdom, South Korea, Italy and China (3–4 respondents per medical organization) using the developed questionnaire to identify the main mechanisms and tools for organizing the export of medical services. SWOT-analysis (Strengths; Weaknesses; Opportunities; Threats) was performed in order to comprehensively evaluate the received information. Results. Along with weaknesses and threats that slow down the development of medical services exports, strengths (internal factors) and opportunities ( external factors) that contribute to the development of medical tourism were also identified: the widespread popularity of the brand of medical organizations abroad which is associated with the provision of premium medical services; versatility and ability to conduct high-tech surgical operations; the presence of a separate premium class building and an international department for working with foreign patients and promoting a medical organization in the world market; well-established business relationships with assistance companies; foreign medical personnel who speak foreign languages and possess necessary skills to treat foreign patients; developed electronic medical care system; developed system of quality control of medical care; the presence of branches in other countries; the presence of a medical visa in the system of legislation; established cooperation with many countries at the embassy level; state licensing and accreditation for the provision of medical services to foreign citzens; the availability of a state website on the provision of medical assistance to foreign citizens; the possibility of the age of value added tax. Conclusion. We identified main patterns in the organization of export of medical services that can be applied to develop this direction in medical organizations of the Russian Federation during the analysis the strengths and weaknesses of four large medical organizations abroad, as well as external factors that affect the work of these medical organizations.
{"title":"Analysis of Current Practices of Organizing the Export of Medical Services in the United Kingdom, Italy, South Korea and China","authors":"A. N. Daykhes, V. Reshetnikov, O. Manerova, I. Mikhailov","doi":"10.31556/2219-0678.2020.39.1.030-042","DOIUrl":"https://doi.org/10.31556/2219-0678.2020.39.1.030-042","url":null,"abstract":"Aim of the study. Analysis of medical tourism’s organizational features based on the example of the large medical organizations in the United Kingdom, South Korea, Italy and China.\u0000\u0000Materials and methods. The data were collected by the authors by interviewing the heads of medical organizations and their deputies in the United Kingdom, South Korea, Italy and China (3–4 respondents per medical organization) using the developed questionnaire to identify the main mechanisms and tools for organizing the export of medical services. SWOT-analysis (Strengths; Weaknesses; Opportunities; Threats) was performed in order to comprehensively evaluate the received information.\u0000\u0000Results. Along with weaknesses and threats that slow down the development of medical services exports, strengths (internal factors) and opportunities ( external factors) that contribute to the development of medical tourism were also identified: the widespread popularity of the brand of medical organizations abroad which is associated with the provision of premium medical services; versatility and ability to conduct high-tech surgical operations; the presence of a separate premium class building and an international department for working with foreign patients and promoting a medical organization in the world market; well-established business relationships with assistance companies; foreign medical personnel who speak foreign languages and possess necessary skills to treat foreign patients; developed electronic medical care system; developed system of quality control of medical care; the presence of branches in other countries; the presence of a medical visa in the system of legislation; established cooperation with many countries at the embassy level; state licensing and accreditation for the provision of medical services to foreign citzens; the availability of a state website on the provision of medical assistance to foreign citizens; the possibility of the age of value added tax.\u0000\u0000Conclusion. We identified main patterns in the organization of export of medical services that can be applied to develop this direction in medical organizations of the Russian Federation during the analysis the strengths and weaknesses of four large medical organizations abroad, as well as external factors that affect the work of these medical organizations.","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87122996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-01DOI: 10.31556/2219-0678.2020.39.1.048-054
O. Zadvornaya
The article is devoted to the development of conceptual approaches to training of personnel for the implementation of lean production technologies in medical organizations – one of the modern directions of optimization of primary health care aimed at intensification of activity processes and elimination of resource losses. Conceptual approaches to the nature of content, structuring of the matrix of competences for application in training and professional activity of organizers of lean production, approaches to the professional basis of design of educational programs have been defined.
{"title":"Conceptual Approaches to the Advanced Training of Lean Production Staff in Medical Organizations Providing Primary Health Care","authors":"O. Zadvornaya","doi":"10.31556/2219-0678.2020.39.1.048-054","DOIUrl":"https://doi.org/10.31556/2219-0678.2020.39.1.048-054","url":null,"abstract":"The article is devoted to the development of conceptual approaches to training of personnel for the implementation of lean production technologies in medical organizations – one of the modern directions of optimization of primary health care aimed at intensification of activity processes and elimination of resource losses. Conceptual approaches to the nature of content, structuring of the matrix of competences for application in training and professional activity of organizers of lean production, approaches to the professional basis of design of educational programs have been defined.","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80596691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-01DOI: 10.31556/2219-0678.2020.39.1.070-079
O. Zhukova, E. Nekaeva, E. S. Khoroshavina, E. Kozlova, Y. Dudukina, Igor Yuryevich Arefyev
Objective: to conduct pharmacoepidemiological analysis and analysis of the costs of pharmacotherapy, taking into account the actual consumption of drugs in the real inpatient clinical practice at the federal center in Russia. Materials and methods. Data from the medical records of 14 patients with burn injury, who were hospitalized in 2018, was analyzed. Patients’ age was from 23 to 67 years (44,93 ± 14,66). Duration of hospitalization was from 17 to 62 days (35,93 ± 14,17). We calculated rate of prescription foe each drug and its share in general structure of all utilized drug courses (n = 460). We performed frequency analysis of prescription structure, DDD (defined daily doses) analysis, DU90% (Drug Utilization 90%) analysis, ABC-analysis and analysis of average cost of pharmacotherapy. Results. Most frequently used drugs, prescribed in 75-100% of all hospital cases, included 15 names, e.g. 2 antimicrobial drugs (vancomycin and amikacin), 19 were used commonly, including 4 antimicrobial drugs (co-trimoxazole, cefoperazone/sulbactam, tigecyclin and cefepime). Other drugs were used in less than 25% of cases. 33 drugs made 90% of all consumed NDDD, including 5 antimicrobial drugs (vancomycin, amikacin, co-trimoxazole, cefoperazone/sulbactam and tigecyclin). These drugs comprised 70,24% in the prescription structure. The cost of one DDD in DU90% segments (512,33 rubles) is 1,4 higher than in DU10% segment (649,34 rubles). Average cost of drugs included in DU90% group was 4735,89 rubles vs 4966,80 rubles for drugs from DU10% group. This finding shows positive tendency of burn injuries pharmacological treatment. Conclusion. We obtained the data, which can be used for comparison of real clinical practice costs with a current payment rates for medical care.
{"title":"Pharmacoepidemiological Analysis of Pharmacotherapy for Burn Injuries in Real Clinical Practice","authors":"O. Zhukova, E. Nekaeva, E. S. Khoroshavina, E. Kozlova, Y. Dudukina, Igor Yuryevich Arefyev","doi":"10.31556/2219-0678.2020.39.1.070-079","DOIUrl":"https://doi.org/10.31556/2219-0678.2020.39.1.070-079","url":null,"abstract":"Objective: to conduct pharmacoepidemiological analysis and analysis of the costs of pharmacotherapy, taking into account the actual consumption of drugs in the real inpatient clinical practice at the federal center in Russia.\u0000\u0000Materials and methods. Data from the medical records of 14 patients with burn injury, who were hospitalized in 2018, was analyzed. Patients’ age was from 23 to 67 years (44,93 ± 14,66). Duration of hospitalization was from 17 to 62 days (35,93 ± 14,17). We calculated rate of prescription foe each drug and its share in general structure of all utilized drug courses (n = 460). We performed frequency analysis of prescription structure, DDD (defined daily doses) analysis, DU90% (Drug Utilization 90%) analysis, ABC-analysis and analysis of average cost of pharmacotherapy.\u0000\u0000Results. Most frequently used drugs, prescribed in 75-100% of all hospital cases, included 15 names, e.g. 2 antimicrobial drugs (vancomycin and amikacin), 19 were used commonly, including 4 antimicrobial drugs (co-trimoxazole, cefoperazone/sulbactam, tigecyclin and cefepime). Other drugs were used in less than 25% of cases. 33 drugs made 90% of all consumed NDDD, including 5 antimicrobial drugs (vancomycin, amikacin, co-trimoxazole, cefoperazone/sulbactam and tigecyclin). These drugs comprised 70,24% in the prescription structure. The cost of one DDD in DU90% segments (512,33 rubles) is 1,4 higher than in DU10% segment (649,34 rubles). Average cost of drugs included in DU90% group was 4735,89 rubles vs 4966,80 rubles for drugs from DU10% group. This finding shows positive tendency of burn injuries pharmacological treatment.\u0000\u0000Conclusion. We obtained the data, which can be used for comparison of real clinical practice costs with a current payment rates for medical care.","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78764156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.17116/medtech20204002150
S. K. Zyryanov, I. Dyakov
{"title":"Pharmacoeconomic evaluation of ceftazidime + avibactam administration in the treatment of nosocomial pneumonia caused by carbapenem-resistant Enterobacteriacea and complicated by bacteremia","authors":"S. K. Zyryanov, I. Dyakov","doi":"10.17116/medtech20204002150","DOIUrl":"https://doi.org/10.17116/medtech20204002150","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74085568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.17116/medtech20204002135
V. A. Nikolaev, A. A. Nikolaev
{"title":"Virtual, augmented and mixed reality technologies in the context of digitalization of healthcare system","authors":"V. A. Nikolaev, A. A. Nikolaev","doi":"10.17116/medtech20204002135","DOIUrl":"https://doi.org/10.17116/medtech20204002135","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75511581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.17116/medtech20204103155
A. Zurdinova, A. Sharaeva
{"title":"Assessment of anticholinergic burden in elderly patients admitted to the hospitals in the Kyrgyz Republic","authors":"A. Zurdinova, A. Sharaeva","doi":"10.17116/medtech20204103155","DOIUrl":"https://doi.org/10.17116/medtech20204103155","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76032154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.17116/medtech20204002126
I. Zheleznyakova, T. A. Khelisupali, V. Omelyanovskiy, S. Tishkina
{"title":"Application of foreign experience of telemedicine services in the Russian Federation","authors":"I. Zheleznyakova, T. A. Khelisupali, V. Omelyanovskiy, S. Tishkina","doi":"10.17116/medtech20204002126","DOIUrl":"https://doi.org/10.17116/medtech20204002126","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76437340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.17116/medtech2020400219
V. Dombrovskiy, N. Musina, L. Melnikova
{"title":"Value-based procurement of medical devices","authors":"V. Dombrovskiy, N. Musina, L. Melnikova","doi":"10.17116/medtech2020400219","DOIUrl":"https://doi.org/10.17116/medtech2020400219","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73876030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.17116/medtech20204002159
Y. Seryapina, D. Fedyaev, N. Musina
{"title":"Incidence of proximal femur fractures in patients aged 60 years and older in the Russian Federation","authors":"Y. Seryapina, D. Fedyaev, N. Musina","doi":"10.17116/medtech20204002159","DOIUrl":"https://doi.org/10.17116/medtech20204002159","url":null,"abstract":"","PeriodicalId":18386,"journal":{"name":"Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор)","volume":"135 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86770805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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