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Recurrent spontaneous pneumothorax in a child 儿童复发性自发性气胸
Pub Date : 2011-12-27 DOI: 10.4038/SLJCC.V2I1.3013
Pradnya S. Bendre, R. Nagargoje, M. Thakur
A 3 year old female child presented with three episodes of left sided pneumothorax in last four months. Patient has minimal respiratory distress in each admission with low grade fever in first two admissions. Intercostal drain was put in first two episodes and VATS with thoracoscopic lung biopsy was done in third episode from left upper lobe with no further episodes of pneumothorax.  DOI: http://dx.doi.org/10.4038/sljcc.v2i1.3013 Sri Lanka Journal of Critical Care Vol.2(1) 2011 29-32
一名三岁女童在过去四个月内出现三次左侧气胸。患者每次入院均有轻微呼吸窘迫,前两次入院均有低烧。前两期行肋间引流,第三期左上肺叶行VATS合并胸腔镜肺活检,无气胸再次发作。DOI: http://dx.doi.org/10.4038/sljcc.v2i1.3013斯里兰卡重症监护杂志Vol.2(1) 2011 29-32
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引用次数: 0
Outcome correlation of change in CRP levels and APACHE II in critically sick patients 危重患者CRP水平变化与APACHE II预后的相关性
Pub Date : 2011-12-27 DOI: 10.4038/SLJCC.V2I1.1057
A. Agarwal, L. Mishra, R. Agarwal, Ghanshyam S. Yadav
Background: Sepsis is one of the main causes of morbidity and mortality in the intensive care unit.[1] C Reactive Protein (CRP), is an acute-­phase reactant, which increases markedly within hours after tissue injury.[4] Changes in plasma CRP levels can be useful in the diagnosis and followup.[5] Objective: To investigate the relation between CRP level and APACHE II score over the duration of illness in critically ill. Material & Methods: A prospective, randomized study was conducted, including 200 patients, aged 25-­65 years, of either sex, fulfilling the systemic inflammatory response (SIRS)/sepsis criteria based on ACCP/SCCM definitions.[5] Patients were divided into two groups (I & II) based upon their outcome. Group I included patients who expired in the I.C.U and Group II patients were those who improved and were shifted from the ICU to their respective wards. At the time of admission and each day thereafter APACHE II scores and CRP levels were carried out till the patients were either shifted from the ICU to wards or expired. Collected data was divided into two groups. Serum CRP levels were measured using an immunochemistry analyzer. Results: Observations showed that the mean CRP values declined beyond day 4 in group II while, the values kept on increasing in group I (table 2, figure 1). The difference between the groups was significant (p Conclusion: The degree of sepsis and organ dysfunction cannot be identified by a single marker; rather a combination of parameters is more useful. DOI: http://dx.doi.org/10.4038/sljcc.v2i1.1057 Sri Lanka Journal of Critical Care Vol.2(1) 2011 25-28
背景:脓毒症是重症监护病房发病和死亡的主要原因之一。[1]C反应蛋白(CRP)是一种急性期反应物,在组织损伤后数小时内显著增加。[4]血浆CRP水平的变化可用于诊断和随访。[5]目的:探讨危重患者病程中CRP水平与APACHEⅱ评分的关系。材料与方法:进行了一项前瞻性随机研究,包括200例患者,年龄25- 65岁,男女均可,符合基于ACCP/SCCM定义的全身炎症反应(SIRS)/败血症标准。[5]根据预后将患者分为两组(I和II)。I组包括在ICU中死亡的患者,II组是病情好转并从ICU转到各自病房的患者。入院时及此后每天进行APACHE II评分和CRP水平检测,直至患者从ICU转至病房或死亡。收集的资料分为两组。用免疫化学分析仪测定血清CRP水平。结果:观察结果显示,II组患者的平均CRP值在第4天以后下降,而I组患者的CRP值继续升高(表2,图1)。两组患者之间的差异具有统计学意义(p)。结论:脓毒症和器官功能障碍的程度不能通过单一标志物来识别;相反,参数的组合更有用。DOI: http://dx.doi.org/10.4038/sljcc.v2i1.1057斯里兰卡重症监护杂志Vol.2(1) 2011 25-28
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引用次数: 1
Carbapenem induced convulsions in the critically ill – A case series. 碳青霉烯在危重病人中诱发惊厥-一个病例系列。
Pub Date : 2011-12-27 DOI: 10.4038/SLJCC.V2I1.2265
C. Goonasekera, G. Manchanayake
Carbapenem induced convulsions are said to be commoner amongst critically ill patients. During a 1½ year study period we observed 4 of 15 patients receiving meropenem and 3 of 7 patients receiving imipenenm develop convulsions in an intensive care unit. The withdrawal of the offending drug rapidly resolved the problem in all but one. DOI: http://dx.doi.org/10.4038/sljcc.v2i1.2265 Sri Lanka Journal of Critical Care Vol.2(1) 2011 13-15
据说碳青霉烯诱发的惊厥在危重病人中较为常见。在为期一年半的研究期间,我们观察到15名接受美罗培南的患者中有4名,7名接受亚胺培南的患者中有3名在重症监护病房发生惊厥。停药后,除了一个人以外,其他所有人的问题都迅速得到了解决。DOI: http://dx.doi.org/10.4038/sljcc.v2i1.2265斯里兰卡重症监护杂志Vol.2(1) 2011 13-15
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引用次数: 0
Mycobacterium tuberculosis Genotypes in patients developing pulmonary tuberculosis related acute respiratory distress syndrome 肺结核相关急性呼吸窘迫综合征患者结核分枝杆菌基因型研究
Pub Date : 2011-12-27 DOI: 10.4038/SLJCC.V2I1.2370
N. Salahuddin, Mahnaz Tanveer, N. Rao, Saeed Akram, Z. Hasan, R. Hasan
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引用次数: 2
Pediatric workload in a multi-disciplinary tertiary care intensive care unit in Sri Lanka 斯里兰卡一个多学科三级护理重症监护室的儿科工作量
Pub Date : 2009-08-12 DOI: 10.4038/SLJCC.V1I1.946
C. Goonasekera, S. P. Mudalige, A. N. W. Karunarathna, I. L. Wickramanayaka
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引用次数: 0
Editorial for the Inaugural Issue 创刊号的社论
Pub Date : 2009-08-11 DOI: 10.4038/SLJCC.V1I1.936
S. Rajapakse
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引用次数: 2
A Computer-Based ICU Patient Alert And Decision Support System 基于计算机的ICU患者警报和决策支持系统
Pub Date : 2009-08-11 DOI: 10.4038/SLJCC.V1I1.942
S. Gunawardane, R. Koggalage, R. Rodrigo, S. Rajapakse
12.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The safety of critically ill patients in intensive care units is an important aspect of medical care. Many human factors contribute to deficiencies and errors in patient care in the intensive care setting, such as long working hours, high levels of stress, lack of enough people, may cause human errors and affecting the effectiveness of the decisions of the physician. Several attempts have been made to increase the effectiveness of such decisions by issuing early alerts on adverse patient conditions. However, such alerts are based on single parameter variations, and not on the relationship between multiple parameter variations. We developed a computer-based model is an integrated solution which identifies adverse patient events based on multiple parameter variations, and then provides predictive treatment suggestions based on the likely clinical conditions which result in the parameter variations. The proposed system follows an interactive communication cycle in order to properly notify the responsible treating physicians at different tiers of responsibility. Our model is capable of early identification of adverse conditions and providing suitable treatment suggestions, thus acting as a decision support system to assist the treating physician. DOI: 10.4038/sljcc.v1i1.942
12.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */表。mso-style-name:"Table Normal";mso-tstyle-rowband-size: 0;mso-tstyle-colband-size: 0;mso-style-noshow:是的;mso-style-priority: 99;mso-style-qformat:是的;mso-style-parent:“”;mso- font - family:宋体;mso-para-margin: 0;mso-para-margin-bottom: .0001pt;mso-pagination: widow-orphan;字体大小:11.0分;字体类型:“Calibri”、“无衬线”;mso-ascii-font-family: Calibri;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:宋体;mso-fareast-theme-font: minor-fareast;mso-hansi-font-family: Calibri;mso-hansi-theme-font: minor-latin;mso-bidi-font-family:宋体;重症监护病房危重病人的安全是医疗护理的一个重要方面。在重症监护环境中,许多人为因素会导致患者护理的不足和错误,例如工作时间长、压力大、人手不足,都可能导致人为错误并影响医生决策的有效性。已经进行了几次尝试,通过对病人的不利情况发出早期警报来提高这种决定的效力。然而,这样的警报是基于单个参数变化,而不是基于多个参数变化之间的关系。我们开发了一个基于计算机的模型,它是一个综合解决方案,可以根据多个参数变化识别患者不良事件,然后根据可能导致参数变化的临床情况提供预测性治疗建议。拟议的系统遵循一个互动的沟通周期,以便正确地通知不同责任层次的负责治疗医生。我们的模型能够早期识别不良状况并提供合适的治疗建议,从而作为辅助治疗医生的决策支持系统。DOI: 10.4038 / sljcc.v1i1.942
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引用次数: 5
Preface: Message from the Director, PGIM 前言:PGIM主任寄语
Pub Date : 2009-08-11 DOI: 10.4038/SLJCC.V1I1.935
R. Sheriff
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引用次数: 0
Management of Sepsis-Induced Acute Kidney Injury 脓毒症致急性肾损伤的处理
Pub Date : 2009-08-11 DOI: 10.4038/SLJCC.V1I1.937
S. Rajapakse, C. Rodrigo, Eranga S. Wijewickrema
12.00 Normal 0 false false false EN-US X-NONE X-NONE 12.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Acute kidney injury (AKI) occurs in a significant proportion of patients with severe sepsis, and is an important cause of mortality in such patients. Current concepts of pathogenesis of AKI are shifting from vasoconstriction-ischaemia induced injury to toxic and immune mediated injury and hyperaemic injury resulting in apoptosis of renal cells.  Renal replacement therapy is the mainstay of management of AKI. Adequacy of dialysis is likely to be linked to better outcome, but there is still no clear consensus on the timing, modality, intensity or frequency of dialysis. Haemodynamically unstable patients usually require modes of continuous renal replacement therapy. Biocompatible dialyser membranes are likely to be safer than older cellulose membranes. Bicarbonate is preferred to acetate and lactate as dialysate buffer.  Anticoagulation has to be undertaken with care to prevent excessive haemorrhage in the setting of already deranged  haemostasis.  Adequate volume resuscitation and maintenance of renal perfusion by the use of vasopressors is beneficial; norepinephrine is the vasopressor of choice. There is no place for the use of low- or renal-dose dopamine, mannitol or frusemide in the setting of sepsis-induced AKI, and in fact they may be detrimental. Prevention of kidney damage by nephrotoxic drugs and radio-contrast media is of vital importance. Careful dose management of nephrotoxic drugs will prevent renal injury. Hydrati
12.00 Normal 0 false false false EN-US X-NONE X-NONE 12.00 Normal 0 false false false false EN-US X-NONE X-NONE /* Style Definitions */表。mso-style-name:"Table Normal";mso-tstyle-rowband-size: 0;mso-tstyle-colband-size: 0;mso-style-noshow:是的;mso-style-priority: 99;mso-style-qformat:是的;mso-style-parent:“”;mso- font - family:宋体;mso-para-margin: 0;mso-para-margin-bottom: .0001pt;mso-pagination: widow-orphan;字体大小:11.0分;字体类型:“Calibri”、“无衬线”;mso-ascii-font-family: Calibri;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:宋体;mso-fareast-theme-font: minor-fareast;mso-hansi-font-family: Calibri;mso-hansi-theme-font: minor-latin;mso-bidi-font-family:宋体;} /*样式定义*/mso-style-name:"Table Normal";mso-tstyle-rowband-size: 0;mso-tstyle-colband-size: 0;mso-style-noshow:是的;mso-style-priority: 99;mso-style-qformat:是的;mso-style-parent:“”;mso- font - family:宋体;mso-para-margin: 0;mso-para-margin-bottom: .0001pt;mso-pagination: widow-orphan;字体大小:11.0分;字体类型:“Calibri”、“无衬线”;mso-ascii-font-family: Calibri;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:宋体;mso-fareast-theme-font: minor-fareast;mso-hansi-font-family: Calibri;mso-hansi-theme-font: minor-latin;mso-bidi-font-family:宋体;急性肾损伤(Acute kidney injury, AKI)在严重脓毒症患者中发生的比例相当大,是严重脓毒症患者死亡的重要原因。目前关于AKI发病机制的概念正在从血管收缩-缺血诱导的损伤转向毒性和免疫介导的损伤以及导致肾细胞凋亡的充血性损伤。肾脏替代疗法是AKI治疗的主要手段。充分的透析可能与更好的结果有关,但对透析的时间、方式、强度或频率仍没有明确的共识。血流动力学不稳定的患者通常需要持续的肾脏替代治疗模式。生物相容性透析膜可能比旧的纤维素膜更安全。碳酸氢盐优于醋酸盐和乳酸盐作为透析液缓冲液。抗凝必须小心地进行,以防止在已经紊乱的止血情况下过度出血。充分的容量复苏和使用血管加压剂维持肾灌注是有益的;去甲肾上腺素是首选的血管加压剂。在脓毒症引起的AKI中,没有使用低剂量或肾剂量多巴胺、甘露醇或氟塞胺的地方,事实上它们可能是有害的。预防肾毒性药物和造影剂对肾脏的损害是至关重要的。仔细管理肾毒性药物的剂量可以防止肾损伤。在给予造影剂之前进行水化可防止肾毒性,但n -乙酰半胱氨酸的益处尚不清楚。严格的血糖控制可能有保护肾的作用,尽管其在严重败血症治疗中的地位目前尚有争议。没有明确的证据表明其他新疗法有益。关键词:重症监护;急性肾损伤;透析;引用本文:Rajapakse S, Rodrigo C, Wijewickrema ES。脓毒症致急性肾损伤的处理。斯里兰卡重症监护杂志2009;1:3-14 DOI: 10.4038/sljcc.v1i1.937
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引用次数: 1
Initial Management Of Patients With Community-Acquired Pneumonia In A Tertiary Hospital In Sri Lanka 斯里兰卡一家三级医院社区获得性肺炎患者的初步管理
Pub Date : 2009-08-11 DOI: 10.4038/SLJCC.V1I1.941
R. Haniffa, H. Ariyaratne, S. D. Fernando, S. Rajapakse
12.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Introduction: We studied the choice of antibiotic/s prescribed on admission and microbiological investigations, in patients hospitalised with community-acquired pneumonia, and compared such choice with published consensus guidelines. Methods:  Adult patients admitted to medical wards of the National Hospital of Sri Lanka with clinical features of pneumonia, with subsequent radiological confirmation, were eligible for inclusion (n=112). Patients who had been in hospital within 10 days of admission, and those with diagnoses of lung malignancy, lung fibrosis, bronchiectasis or tuberculosis were excluded. We obtained data from the patients' case records regarding indicators of severity, the antibiotic prescribed on admission, and route of administration. The microbiological investigations performed were also recorded. We compared the practices with guidelines for management of community-acquired pneumonia published by the British Thoracic Society in 2001. Results: The respiratory rate, a core clinical adverse prognostic feature, was documented in only 13% of case records. Oral amoxicillin was the most common antibiotic prescribed on admission, with 29% of hospitalized patients receiving it. Erythromycin was included in the drug regimen in only 18% of all patients. Intravenous antibiotics were started for 44% of cases without any documented adverse prognostic features on admission. Sputum was sent for acid-fast bacilli staining in 48% of patients and for bacterial culture in 11%. Blood culture was performed in 5% of patients. Conclusion: Documentation of severity criteria is often incomplete. There is inadequate utilization of oral macrolide antibiotics to cover atypical pathogens. Intravenous antibiotics are overused in hospitalized patients with community-acquired pneumonia. DOI: 10.4038/sljcc.v1i1.941
12.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */表。mso-style-name:"Table Normal";mso-tstyle-rowband-size: 0;mso-tstyle-colband-size: 0;mso-style-noshow:是的;mso-style-priority: 99;mso-style-qformat:是的;mso-style-parent:“”;mso- font - family:宋体;mso-para-margin: 0;mso-para-margin-bottom: .0001pt;mso-pagination: widow-orphan;字体大小:11.0分;字体类型:“Calibri”、“无衬线”;mso-ascii-font-family: Calibri;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:宋体;mso-fareast-theme-font: minor-fareast;mso-hansi-font-family: Calibri;mso-hansi-theme-font: minor-latin;mso-bidi-font-family:宋体;前言:我们研究了社区获得性肺炎住院患者入院时抗生素处方的选择和微生物学调查,并将这种选择与已发表的共识指南进行了比较。方法:斯里兰卡国立医院内科病房收治的具有肺炎临床特征并经放射学证实的成年患者(n=112)符合纳入条件。排除入院10天内住院的患者,以及诊断为肺恶性肿瘤、肺纤维化、支气管扩张或结核病的患者。我们从患者的病例记录中获得了关于严重程度指标、入院时处方的抗生素和给药途径的数据。还记录了所进行的微生物调查。我们将这些做法与2001年英国胸科学会发布的社区获得性肺炎管理指南进行了比较。结果:呼吸频率,一个核心的临床不良预后特征,只有13%的病例记录被记录。口服阿莫西林是入院时最常见的抗生素处方,29%的住院患者接受了它。只有18%的患者将红霉素纳入药物治疗方案。入院时无任何不良预后特征的44%的病例开始静脉注射抗生素。48%的患者送痰进行抗酸杆菌染色,11%的患者送痰进行细菌培养。5%的患者进行了血培养。结论:严重程度标准的文件通常是不完整的。口服大环内酯类抗生素用于治疗非典型病原体的使用不足。社区获得性肺炎住院患者静脉注射抗生素被过度使用。DOI: 10.4038 / sljcc.v1i1.941
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引用次数: 1
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Sri Lanka Journal of Critical Care
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