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Point-of-care ultrasound training in infectious diseases: Educational models, challenges, and multi-sectoral roles. 传染病护理点超声培训:教育模式、挑战和多部门角色。
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-06 DOI: 10.1016/j.medcli.2025.107341
Samuel García-Rubio, Suean Pascoe, Yale Tung-Chen

Point-of-care ultrasound (POCUS) has become an essential diagnostic and procedural adjunct in infectious disease practice, providing real-time bedside evaluation that improves patient outcomes. Despite its clinical relevance, broad implementation faces educational challenges, including limited access to hands-on training, inconsistent curricular integration, and lack of standardized certification pathways across all stages of medical education. This review frames POCUS education as a longitudinal, progressive pathway starting with foundational exposure in undergraduate medical curricula and advancing through competency-based postgraduate training, continuing professional development, and formal credentialing. Key educational frameworks such as G.O.O.S.E. and I-AIM structure the acquisition of both technical imaging skills and clinical integration, fostering critical ultrasound competence. Various stakeholders contribute to this continuum: medical schools form the foundational base; private sector programs fill training gaps using innovative educational approaches including immersive workshops, simulation, blended learning, and small-group pathology-focused sessions; and scientific societies provide leadership by defining standards, supporting collaborative research, and advocating for formalized training and certification. These innovative training modalities enable flexible, practical skill acquisition tailored to evolving clinical needs and diverse practice environments, accelerating learners' progression toward competent, autonomous ultrasound use. Such approaches are especially valuable in resource-limited settings or where traditional academic resources are constrained. Sustained multisectoral collaboration among academic institutions, private educators, scientific societies, and regulatory bodies is vital to ensure accessible, effective, and equitable POCUS training worldwide. By outlining this comprehensive educational roadmap and recognizing ongoing innovations, this review aims to guide the integration of POCUS into infectious disease care, ultimately improving global patient outcomes.

即时超声(POCUS)已成为传染病实践中必不可少的诊断和程序辅助手段,提供实时床边评估,改善患者预后。尽管它具有临床意义,但广泛的实施面临着教育方面的挑战,包括获得实践培训的机会有限,课程整合不一致,以及在医学教育的各个阶段缺乏标准化的认证途径。本综述将POCUS教育作为一个纵向的、渐进的途径,从本科医学课程的基础接触开始,通过基于能力的研究生培训、持续的专业发展和正式的资格认证。关键的教育框架,如G.O.O.S.E.和I-AIM结构的获取技术成像技能和临床整合,培养关键的超声能力。各种利益攸关方为这一连续体作出了贡献:医学院构成了基础;私营部门项目利用创新的教育方法填补培训空白,包括沉浸式研讨会、模拟、混合学习和以病理学为重点的小组会议;科学协会通过定义标准、支持合作研究和倡导正式的培训和认证来发挥领导作用。这些创新的培训模式使灵活、实用的技能获得量身定制,以适应不断变化的临床需求和多样化的实践环境,加速学习者向有能力、自主使用超声的方向发展。这种方法在资源有限或传统学术资源有限的情况下特别有价值。学术机构、私立教育机构、科学社团和监管机构之间持续的多部门合作对于确保全球范围内POCUS培训的可及性、有效性和公平性至关重要。通过概述这一全面的教育路线图并认识到正在进行的创新,本综述旨在指导POCUS与传染病护理的整合,最终改善全球患者的预后。
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引用次数: 0
Growth after pubertal block in trans adolescents. 跨性别青少年青春期阻滞后的生长。
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-04 DOI: 10.1016/j.medcli.2025.107343
Jesus Domingez-Riscart, Ana García-Zarzuela, Blanca Romero-Sayago, Sandra Ruiz-Ramos, Almudena Lara-Barea, Isabel Mateo-Gavira

Introduction: Transgender people show incongruence between the sex assigned at birth and the gender they identify with. Puberty generates hormonal changes that induce physical changes, with the development of secondary sexual character, which cause great discomfort in the transgender individual. It is also a vital time when there is an increase in the rate of growth. The drug GnRHa stops puberty, slowing down the changes in the body and allowing the adolescent time to consider their gender identity. However, an expected side effect of these drugs is that growth velocity is affected.

Objective: To determine the growth velocity of adolescents and transgender children undergoing pubertal blocking therapies.

Material and methods: We conducted a longitudinal study using anthropometric and laboratory measurements every 6months, collected 1year before and 2years after blockade, to assess whether growth velocity and height are affected by pubertal blockade. The comparison was made using the standard deviations of the variables according to age, using the Wilcoxon signed-rank test in paired groups and the U-Mann Whitney test in independent groups. To obtain the data, we reviewed the medical records of the participants in our study.

Results: Fifty-five transgender adolescents initiating pubertal blocking with a median age of 11.8years are studied. It is observed that height measured in standard deviations (SD) and growth velocity, measured in centimetres and SD, decrease in accordance with increasing time in pubertal block. When comparing transgender boys and girls, transgender girls show a greater decrease in height SD. These differences are statistically significant for pre-blocking, 6 and 12months of BP therapy (P=.036, P=.005 and P=.042 respectively). In addition, it was also observed that growth velocity was more affected in trans girls than in boys, although these differences were not statistically significant.

Conclusions: Height and growth velocity are decreased when puberty is blocked. This decrease is more striking in transgender girls than in transgender boys.

简介:跨性别者表现出出生时的生理性别与他们认同的性别之间的不一致。青春期会产生荷尔蒙的变化,从而引起身体的变化,伴随第二性征的发展,这会给跨性别者带来很大的不适。这也是经济增长速度加快的关键时期。药物GnRHa阻止青春期,减缓身体的变化,让青少年有时间考虑他们的性别认同。然而,这些药物的一个预期副作用是生长速度受到影响。目的:了解接受青春期阻断治疗的青少年和变性儿童的生长速度。材料和方法:我们每6个月通过人体测量和实验室测量进行纵向研究,收集阻断前1年和阻断后2年的数据,以评估青春期阻断是否影响生长速度和身高。采用各变量随年龄的标准差进行比较,配对组采用Wilcoxon符号秩检验,独立组采用U-Mann Whitney检验。为了获得数据,我们查阅了研究参与者的医疗记录。结果:对55名中位年龄为11.8岁的跨性别青少年进行了研究。以标准差(SD)表示的身高和以厘米和SD表示的生长速度随青春期阻滞时间的增加而降低。当比较跨性别男孩和女孩时,跨性别女孩的身高SD下降幅度更大。这些差异在阻断前、6个月和12个月的BP治疗中具有统计学意义(P= 0.036、P= 0.005和P= 0.042)。此外,还观察到变性女孩的生长速度比男孩更受影响,尽管这些差异没有统计学意义。结论:青春期阻滞会导致身高和生长速度下降。这种下降在变性女孩中比在变性男孩中更为显著。
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引用次数: 0
Chronic diarrhea and infiltrative duodenal lesions caused by Chromobacterium violaceum in a kidney transplant recipient. 肾移植受者紫色色杆菌致慢性腹泻及浸润性十二指肠病变1例。
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-02 DOI: 10.1016/j.medcli.2025.107294
Julya de Assis Sousa Morais, Diogo Buarque Cordeiro Cabral, Euclides Dias Martins Filho
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引用次数: 0
Papel de la ecografía en la enfermedad pediátrica infecciosa 超声在儿科传染病中的作用
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-01 DOI: 10.1016/j.medcli.2025.107323
Ecatherine Rodríguez Urteaga , Susana Viver Gómez
Infectious diseases remain a leading cause of pediatric consultations despite significant advances in their prevention and treatment. Clinical ultrasound has emerged as a valuable diagnostic tool in the pediatric setting due to its non-ionizing nature, the absence of need for sedation, its feasibility at the point of care, and its safety, reproducibility, and current availability.
In this article, we review pediatric infectious conditions in which clinical ultrasound contributes significantly to diagnosis, follow-up, and clinical decision-making. This is a narrative review based on both the available evidence and clinical experience regarding the role of ultrasound in pediatric infectious pathology.
Ultrasound is useful in the vast majority of pediatric infectious diseases, including respiratory infections (pneumonia, bronchiolitis), cutaneous and musculoskeletal infections (cellulitis, myositis, abscesses, osteomyelitis, arthritis), abdominal infections (appendicitis, mesenteric adenitis, intra-abdominal abscesses), urinary tract infections (pyelonephritis, renal abscess), cervical infections (adenitis, deep neck abscesses, parotitis), and genital infections (epididymitis, orchitis, scrotal abscesses). It allows the identification of characteristic findings in each condition, with good clinical and radiological correlation. Ultrasound also aids in drainage procedures, helps avoid unnecessary invasive interventions, and facilitates the monitoring of patient progress.
Point-of-care ultrasound (POCUS) has become a key tool in the diagnosis, management, and follow-up of pediatric infections.
尽管传染病的预防和治疗取得了重大进展,但传染病仍然是儿科就诊的主要原因。临床超声由于其非电离性、不需要镇静、在护理点上的可行性、安全性、可重复性和当前可用性,已成为儿科环境中有价值的诊断工具。在这篇文章中,我们回顾了临床超声对儿科感染性疾病的诊断、随访和临床决策的重要贡献。这是一篇基于现有证据和临床经验的关于超声在儿科感染病理学中的作用的叙述性综述。超声在绝大多数儿科传染病中都是有用的,包括呼吸道感染(肺炎、细支气管炎)、皮肤和肌肉骨骼感染(蜂窝织炎、肌炎、脓肿、骨髓炎、关节炎)、腹部感染(阑尾炎、肠系膜腺炎、腹内脓肿)、尿路感染(肾盂肾炎、肾脓肿)、宫颈感染(腺炎、深颈脓肿、腮腺炎)和生殖器感染(附睾炎、睾丸炎、阴囊脓肿)。它可以识别每种情况下的特征性发现,具有良好的临床和放射学相关性。超声也有助于引流过程,有助于避免不必要的侵入性干预,并有利于监测病人的进展。即时超声(POCUS)已成为儿科感染诊断、管理和随访的关键工具。
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引用次数: 0
Valor pronóstico del uso combinado de biomarcadores NT-proBNP y CA125 en una cohorte de 138 pacientes con insuficiencia cardiaca con fracción de eyección reducida 138例低射出率心力衰竭患者队列中NT-proBNP和CA125联合使用生物标志物的预测值
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-30 DOI: 10.1016/j.medcli.2025.107277
Nouha Yacub Briceño , Alberto Jesús Torres Zamudio , Jorge Perea Armijo , José López-Aguilera
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引用次数: 0
Tumores de restos adrenales testiculares e hiperplasia suprarrenal congénita 睾丸残余肾上腺肿瘤和先天性肾上腺增生
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-30 DOI: 10.1016/j.medcli.2025.107296
Marc Martín Hernández, Álex Gil Ordoñez, Daniel Vas
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引用次数: 0
Utility of ultrasound in the diagnosis of intraabdominal infections 超声在腹内感染诊断中的应用
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-29 DOI: 10.1016/j.medcli.2025.107334
Ana Segura Grau , Paula Martín-Borregón Bendito , Elena Segura Grau
Intra-abdominal infection is a potentially serious condition that requires early and accurate diagnosis. Point-of-care ultrasound (POCUS) has emerged as a key diagnostic tool due to its safety, availability, low cost, and bedside applicability. It offers several advantages over other imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI), although its diagnostic performance strongly depends on the operator's expertise. Ultrasound is particularly useful in diagnosing common conditions such as appendicitis, cholecystitis, cholangitis, liver abscesses, pyelonephritis, and complicated renal colic. In each of these scenarios, POCUS enables rapid assessment, guides therapeutic decisions, and may reduce complications, radiation exposure, and time to diagnosis. Multiple studies support its diagnostic reliability, reporting high sensitivity and specificity when performed by trained professionals. Despite its technical limitations, POCUS plays a fundamental role in emergency settings and in contexts with limited access to advanced imaging.
腹内感染是一种潜在的严重疾病,需要早期准确诊断。由于其安全性、可用性、低成本和床边适用性,POCUS已成为一种关键的诊断工具。与计算机断层扫描(CT)和磁共振成像(MRI)等其他成像方式相比,它具有许多优势,尽管其诊断性能在很大程度上取决于操作人员的专业知识。超声在诊断阑尾炎、胆囊炎、胆管炎、肝脓肿、肾盂肾炎和复杂的肾绞痛等常见疾病时特别有用。在这些情况下,POCUS能够快速评估,指导治疗决策,并可能减少并发症,辐射暴露和诊断时间。多项研究支持其诊断可靠性,报告了由训练有素的专业人员执行时的高灵敏度和特异性。尽管POCUS有技术上的局限性,但它在紧急情况下和在无法获得先进成像的情况下发挥着重要作用。
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引用次数: 0
Hepatitis enfisematosa fulminante
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-29 DOI: 10.1016/j.medcli.2025.107295
Inés Alonso Envid , Ángel Lafuente los Arcos , José Enrique Alonso Formento , Carlos Pardillos Marín , María del Carmen Orts Cansino , Elisa Simó Gaztambide
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引用次数: 0
La enfermedad por reflujo gastroesofágico en el siglo XXI 21世纪的胃食管反流病
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-29 DOI: 10.1016/j.medcli.2025.107047
Antonio M. Caballero-Mateos , Cristina Bailón-Gaona , Guillermo A. Cañadas de la Fuente
Gastroesophageal reflux disease (GERD) is a chronic disorder affecting a significant proportion of the global population, characterized by heartburn and regurgitation, and potentially associated with serious complications such as esophagitis, Barrett's esophagus, and adenocarcinoma. Its multifactorial pathophysiology includes alterations in the lower esophageal sphincter, motility, or visceral sensitivity. Diagnosis is based on a combination of clinical criteria and complementary tests such as endoscopy, pH monitoring, and impedance testing. Management includes non-pharmacological strategies like lifestyle and dietary changes, along with pharmacological therapy, with proton pump inhibitors being the cornerstone of treatment. Newer options, such as potassium-competitive acid blockers (vonoprazan), have shown promising benefits in refractory cases. This article synthesizes the most updated evidence on GERD, providing a comprehensive overview of its pathophysiology, diagnosis, and therapeutic options.
胃食管反流病(GERD)是一种影响全球很大一部分人群的慢性疾病,以胃灼热和反流为特征,并可能与严重并发症如食管炎、巴雷特食管和腺癌相关。其多因素病理生理包括食管下括约肌、运动性或内脏敏感性的改变。诊断是基于临床标准和补充测试,如内窥镜检查,pH监测和阻抗测试的组合。治疗包括非药物策略,如生活方式和饮食的改变,以及药物治疗,质子泵抑制剂是治疗的基石。较新的选择,如钾竞争性酸阻滞剂(伏诺哌赞),在难治性病例中显示出有希望的益处。本文综合了关于胃食管反流的最新证据,提供了其病理生理、诊断和治疗选择的全面概述。
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引用次数: 0
Impact of a healthcare network “Aorta Code” on outcomes of elderly patients with type A acute aortic syndrome 医疗网络“主动脉密码”对老年a型急性主动脉综合征患者预后的影响
IF 2.1 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-29 DOI: 10.1016/j.medcli.2025.107306
Inés Ramos González-Cristóbal , Carlos Ferrera , Manuel Carnero-Alcázar , Ana Carrero , Enrique del Toro , Esther Álvarez , Carlos Alonso , Tirso Alonso Ares , Ana Viana-Tejedor , Isaac Martínez , Ana Bustos , Rosa Beltrao , Francisco Javier Noriega , Gabriela Tirado , Javier Cobiella , Luis Maroto , Isidre Vilacosta

Background and objectives

Type A-acute aortic syndrome (AAS-A) is associated with a high morbidity and mortality. The management of elderly patients with AAS-A is challenging. The aim of this study was to evaluate the current prognosis of elderly patients with AAS-A, and to analyze the impact of surgery on a healthcare network.

Methods

Patients with AAS-A were prospectively and consecutively collected from 2019 to 2024 in a four-hospital network “Aorta Code” with a tertiary care referral centre for cardiac surgery. Patients were classified according to age into two groups: ≥75-year-old and under 75-year-old. Clinical, diagnostic, treatment and prognostic variables were analyzed. Primary outcomes included 30-day mortality, time from symptoms to diagnosis and time from diagnosis to surgery.

Results

A total of 102 patients were included. Of these, 36 were ≥75-year-old. Most patients (90%) had classical aortic dissection. The length of the aortic injury was shorter in the elder group. Older patients had more comorbidities, most were frail and mildly dependent, and took longer to be diagnosed. Complications at the time of diagnosis and time from diagnosis to surgery were similar in both groups. Preoperative mortality risk was higher in elderly patients and surgery was less extensive on them. Surgery was associated with a mortality reduction in both groups.

Conclusions

Elderly patients with AAS-A have more comorbidities, are diagnosed later and have higher mortality than younger patients. Yet, in a dedicated healthcare network, surgery is associated with a reduction in mortality even in the older population.
背景与目的a型急性主动脉综合征(AAS-A)具有较高的发病率和死亡率。老年AAS-A患者的管理具有挑战性。本研究的目的是评估老年AAS-A患者目前的预后,并分析手术对医疗网络的影响。方法前瞻性和连续收集2019 - 2024年四医院网络“主动脉编码”与心脏外科三级保健转诊中心的AAS-A患者。患者按年龄分为≥75岁和75岁以下两组。分析临床、诊断、治疗和预后变量。主要结局包括30天死亡率、从症状到诊断的时间和从诊断到手术的时间。结果共纳入102例患者。其中36人年龄≥75岁。大多数患者(90%)为典型主动脉夹层。老年组主动脉损伤长度较短。老年患者有更多的合并症,大多数虚弱和轻度依赖,需要更长的时间才能确诊。两组的并发症在诊断时和从诊断到手术的时间相似。老年患者术前死亡风险较高,手术范围较小。手术与两组的死亡率降低有关。结论老年AAS-A患者合并症多,诊断晚,病死率高。然而,在专门的医疗保健网络中,手术与死亡率的降低有关,即使在老年人中也是如此。
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引用次数: 0
期刊
Medicina Clinica
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