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Comparative study of ropivacaine and nalbuphine and ropivacaine alone in PNS guided supraclavicular brachial plexus block 罗哌卡因与纳布啡及单独罗哌卡因在PNS引导下锁骨上臂丛阻滞中的比较研究
Pub Date : 2021-01-01 DOI: 10.26611/10152132
Shraddha Kangad
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引用次数: 0
Comparative study between epidural bupivacaine with fentanyl versus ropivacaine with fentanyl combination for post operative analgesia in lower abdominal and lower limb surgeries 硬膜外布比卡因联合芬太尼与罗哌卡因联合芬太尼用于下腹部和下肢手术后镇痛的比较研究
Pub Date : 2021-01-01 DOI: 10.26611/101519313
Sudeep Sirga
Background: Adequate analgesia aids to restore normal functions including ventilation, coughing and mobility, thereby facilitating early rehabilitation and shortened hospital stay. Present study was aimed to compare epidural Bupivacaine with fentanyl versus ropivacaine with fentanyl combination for post operative analgesia in lower abdominal and lower limb surgeries at a tertiary hospital. Material and Methods: Present study was comparative, interventional study, conducted in patients aged 18–65 years, either gender, American Society of Anesthesiologists (ASA) physical status I–II, posted for elective lower abdominal and lower limb surgeries. This single-blind study comprised a sample size of 30 patients randomly allocated (by computer generates list) into two groups as Group R (0.125% ropivacaine with 1 ug/ml fentanyl) and Group B (0.125% bupivacaine with 1 ug/ml fentanyl). Results: We compared various parameters such as Age (years), Weight (kg), BMI (kg/m2), Gender, ASA status, Type of surgery, Duration of surgery (min), Intraoperative fentanyl (μg), Catheter insertion level (L1-L2/L2-L3), all parameters were comparable and difference was not significant statistically. Common surgeries considered for study were ovarian debulking surgeries, Wertheim’s hysterectomy, orthopaedic lower limb surgeries (THR, TKR) and hemicolectomy. Post-operative analgesia was calculated on basis of VAS scores. We noted in less post-operative VAS scores at 6,12,18 hours in group R and difference was statistically significant. Conclusion: Epidural ropivacaine with fentanyl combination seems to be a better alternative to epidural bupivacaine with fentanyl, as it provides comparable stable hemodynamics, early onset and prolonged post‑op analgesia, lower consumption of post‑op local anaesthetic for epidural analgesia.
背景:充分的镇痛有助于恢复正常功能,包括通气、咳嗽和活动能力,从而促进早期康复和缩短住院时间。本研究旨在比较某三级医院硬膜外布比卡因联合芬太尼与罗哌卡因联合芬太尼在下腹部和下肢手术中的术后镇痛效果。材料和方法:本研究是一项对比性、介入性研究,研究对象为年龄18-65岁、美国麻醉医师协会(ASA)身体状况I-II级、择期下腹和下肢手术的患者。这项单盲研究包括30例患者的样本,随机分为两组:R组(0.125%罗哌卡因加1 ug/ml芬太尼)和B组(0.125%布比卡因加1 ug/ml芬太尼)。结果:我们比较了年龄(years)、体重(kg)、BMI (kg/m2)、性别、ASA状态、手术类型、手术时间(min)、术中芬太尼(μg)、置管水平(L1-L2/L2-L3)等各项参数,所有参数具有可比性,差异无统计学意义。研究中考虑的常见手术有卵巢减容手术、韦特海姆氏子宫切除术、骨科下肢手术(THR、TKR)和结肠切除术。根据VAS评分计算术后镇痛。我们注意到R组术后6、12、18小时VAS评分较低,差异有统计学意义。结论:硬膜外罗哌卡因联合芬太尼似乎是硬膜外布比卡因联合芬太尼的更好选择,其血流动力学稳定,术后镇痛起效早,镇痛时间长,术后局麻用量少。
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引用次数: 0
A comparative study of dexmedetomidine versus clonidine to attenuate the hemodynamic response to laryngoscopy and endotracheal intubation 右美托咪定与可乐定减轻喉镜和气管插管后血流动力学反应的比较研究
Pub Date : 2021-01-01 DOI: 10.26611/10152017
Sachin Madhukar Kumbhar
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引用次数: 0
Compare study on incidence of PDPH using 25g QUINCKE and 25g WHITACRE needles undergoing elective surgery by spinal anaesthesia 25g QUINCKE针与25g WHITACRE针择期脊髓麻醉手术中PDPH发生率的比较研究
Pub Date : 2021-01-01 DOI: 10.26611/10152123
S. Premkumar
{"title":"Compare study on incidence of PDPH using 25g QUINCKE and 25g WHITACRE needles undergoing elective surgery by spinal anaesthesia","authors":"S. Premkumar","doi":"10.26611/10152123","DOIUrl":"https://doi.org/10.26611/10152123","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88472057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of virtual reality on pain during intravenous cannulation and preoperative separation anxiety in paediatric patients: A prospective randomised study 虚拟现实在儿科患者静脉插管疼痛和术前分离焦虑中的作用:一项前瞻性随机研究
Pub Date : 2021-01-01 DOI: 10.26611/10151923
L. ShilpaH, Uttarahalli Main Road Kengeri Bengaluru Karnataka India. Education City
Background: Pain and anxiety in paediatric patients creates significant problems for the patients and the treating physicians. Virtual reality is a relatively new intervention that can be used to provide distraction. Aim: The aim of the proposed study is to evaluate virtual reality (VR) as a non-pharmacological intervention tool to reduce pain and anxiety in patients of paediatric age group undergoing intravenous cannulation. Methods: This was a prospective randomised trial that enrolled paediatric patients of age group 7-11 years. Patients were randomly allocated to virtual reality group where they were made to wear VR headgear and videos were played and standard Emla cream group where cream was applied at the intended site of intravenous cannulation. Results: Patients using VR exhibited lower pain and anxiety score during intravenous cannulation. Conclusions: This current study found that application of immersive VR had better pain alleviation and parent separation anxiety score when compared with non-VR group patient.
背景:儿科患者的疼痛和焦虑给患者和治疗医生带来了严重的问题。虚拟现实是一种相对较新的干预手段,可以用来分散注意力。目的:本研究的目的是评估虚拟现实(VR)作为一种非药物干预工具,以减轻儿科年龄组接受静脉插管患者的疼痛和焦虑。方法:这是一项前瞻性随机试验,招募了7-11岁的儿童患者。患者被随机分配到虚拟现实组,他们被要求佩戴VR头盔并播放视频,标准Emla乳膏组,在静脉插管的预定部位涂抹乳膏。结果:使用VR的患者在静脉置管过程中疼痛和焦虑评分较低。结论:本研究发现,沉浸式VR应用在缓解疼痛和父母分离焦虑评分方面优于非VR组。
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引用次数: 0
Study of biochemical markers as a prognostic indicators in Covid 19 patients 生化指标作为新冠肺炎患者预后指标的研究
Pub Date : 2021-01-01 DOI: 10.26611/101520315
S. M
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引用次数: 0
A Randomized comparative study: Prophylactic use of phenylephrine infusion versus phenylephrine bolus to treat hypotension in caesarean section patients 一项随机比较研究:预防性使用苯肾上腺素输注与苯肾上腺素丸治疗剖宫产患者低血压
Pub Date : 2021-01-01 DOI: 10.26611/10152033
S. Kulkarni
{"title":"A Randomized comparative study: Prophylactic use of phenylephrine infusion versus phenylephrine bolus to treat hypotension in caesarean section patients","authors":"S. Kulkarni","doi":"10.26611/10152033","DOIUrl":"https://doi.org/10.26611/10152033","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"2014 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86606699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of hemodynamic parameters and cardiac function in patients undergoing laparoscopic cholecystectomy in patients with moderate to severe left ventricular dysfunction 中重度左心室功能不全行腹腔镜胆囊切除术患者血流动力学参数和心功能的研究
Pub Date : 2021-01-01 DOI: 10.26611/10152014
Varsha Sapehia
{"title":"Study of hemodynamic parameters and cardiac function in patients undergoing laparoscopic cholecystectomy in patients with moderate to severe left ventricular dysfunction","authors":"Varsha Sapehia","doi":"10.26611/10152014","DOIUrl":"https://doi.org/10.26611/10152014","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84213495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of desflurane requirement and recovery characteristics in entropy guided general anaesthesia with or without dexmedetomidine infusion 熵导全麻输注右美托咪定前后地氟醚需要量及恢复特点的比较研究
Pub Date : 2021-01-01 DOI: 10.26611/10151935
Rajesh R. Nayak
Background: Newer anaesthetics such as desflurane have smaller blood-gas partition coefficient than older ones like halothane. Desflurane is preferred because it leads to faster onset of anaesthesia and faster emergence from anaesthesia. However, desflurane is considered to be more expensive than other volatile anaesthetics. Highly selective alpha two adrenoceptor agonists like Dexmedetomidine reduce anaesthetic requirements. Hence this study was designed to compare the effect of Dexmedetomidine infusion on desflurane consumption and recovery characteristics under entropy guided general anaesthesia. Materials and Methods: Fifty patients aged between 18-55 years belonging to ASA I and II scheduled for elective surgeries under general anaesthesia were randomly divided into two groups. Group D patients received a loading dose of inj Dexmedetomidine 1 µg/ kg, over 10 minutes before the induction of anaesthesia, and 0.5 µg/ kg/ hour infusion following induction of anaesthesia till the end of surgery. Group P patients received similar volumes of normal saline as bolus before the induction and maintenance infusion till the end of the surgery. Desflurane concentration was adjusted to maintain response entropy values between 40 to 60 and based on clinical variables like heart rate (HR), and mean arterial pressure (MAP). Muscle relaxation was guided by TOF count. HR, NIBP, MAP, SPO2, ENTROPY values were recorded. The total desflurane consumption was recorded from Anaesthesia gas module of GE Datex-Ohmeda S 5 Advance system. At end of surgery, desflurane was discontinued and patient extubated after adequate recovery and when TOF ratio was more than 0.9. Time to eye opening, extubation, response to verbal commands were recorded. Results: The mean consumption of desflurane at the end of one hour was significantly less in group D with p<0.001 (Group P 21.04±6.33 ml/hr and Group D 14.44±1.83 ml/hr). Eye opening time was significantly less in group D with p<0.001(Group P 297.60± 89.97sec and Group D 169.80±22.48 sec). Time for response to verbal commands was significantly less in group D with p<0.001 (Group P 423.60±113.02 sec and Group D 269.80±45.29 sec) Conclusion: Intraoperative Dexmedetomidine infusion reduces desflurane consumption, hastens recovery from desflurane during entropy guided general anaesthesia.
背景:地氟醚等新型麻醉剂的血气分配系数比氟烷等旧麻醉剂小。地氟醚是首选,因为它会导致更快的麻醉开始和更快的麻醉恢复。然而,地氟醚被认为比其他挥发性麻醉剂更昂贵。高选择性α 2肾上腺素能受体激动剂如右美托咪定可减少麻醉需求。因此,本研究旨在比较右美托咪定输注对熵导全身麻醉下地氟醚消耗和恢复特征的影响。材料与方法:50例年龄在18 ~ 55岁之间,属于ASA I、II级,在全麻条件下择期手术的患者随机分为两组。D组患者在麻醉前10分钟注射右美托咪定负荷剂量1µg/ kg,麻醉后每小时注射0.5µg/ kg,直至手术结束。P组患者诱导前给予等量生理盐水,维持输注至手术结束。根据心率(HR)、平均动脉压(MAP)等临床变量调整地氟醚浓度,使反应熵值维持在40 ~ 60之间。TOF计数指导肌肉放松。记录HR、NIBP、MAP、SPO2、ENTROPY值。从GE Datex-Ohmeda s5 Advance系统的麻醉气体模块记录地氟醚总消耗量。手术结束时,当TOF比大于0.9时,患者充分恢复后停用地氟醚并拔管。记录睁眼时间、拔管时间、对口头命令的反应时间。结果:D组患者1 h时地氟醚平均耗量显著低于D组,p<0.001 (p< 21.04±6.33 ml/hr, p< 14.44±1.83 ml/hr)。D组患者睁眼时间显著少于p<0.001(p组297.60±89.97秒,D组169.80±22.48秒)。D组患者对言语指令的反应时间明显少于p<0.001 (p组423.60±113.02秒,D组269.80±45.29秒)。结论:术中右美托咪定可减少地氟醚的消耗,加速熵导全身麻醉后地氟醚的恢复。
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引用次数: 0
Evaluation of efficacy of intrathecal clonidine as an adjuvant to bupivacaine in patients undergoing transurethral resection of prostate 经尿道前列腺切除术患者鞘内可乐定辅助布比卡因的疗效评价
Pub Date : 2021-01-01 DOI: 10.26611/101520317
R. K
{"title":"Evaluation of efficacy of intrathecal clonidine as an adjuvant to bupivacaine in patients undergoing transurethral resection of prostate","authors":"R. K","doi":"10.26611/101520317","DOIUrl":"https://doi.org/10.26611/101520317","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89821863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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MedPulse International Journal of Anesthesiology
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