{"title":"Evaluation of hemodynamic changes during laparoscopic cholecystectomy in patients with moderate to severe left ventricular dysfunction: A prospective observational controlled study","authors":"V. .","doi":"10.26611/101521316","DOIUrl":"https://doi.org/10.26611/101521316","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91212468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Relief of post operative pain with minimal side effects is a major goal during postanesthesia care. Intravenous fentanyl has been the gold standard for post operative pain relief. Fentanyl is a mu opioid receptor agonist characterised by high potency, rapid onset, short duration of action, lipid solubility and an apparent absence of serious side effects normally associated with opioids. Aim: To compare analgesic efficacy of nebulised fentanyl with intravenous fentanyl for post operative pain relief in patients undergoing breast surgeries under general anesthesia. Objectives: 1. To assess the analgesic efficacy of nebulised fentanyl in comparison to IV fentanyl for post-operative pain relief after breast surgeries. 2. To study Incidence and severity of side effects of fentanyl such as sedation, postoperative nausea and vomiting, respiratory depression, if any. Methodology: After our Hospital Research and Ethics Committee approval and obtaining informed written consent 90 patients aged between 20 and 65 years, belonging to ASA physical status I or II who were scheduled for elective breast surgeries under general anesthesia were included in this randomized control study. The patients were randomly assigned into three groups of 30 patients each to receive either Intravenous fentanyl 1mcg/kg (group C), or nebulised Fentanyl 2mcg/kg (Group N1) and nebulised Fentanyl 3mcg/kg (group N2). Results: These patients in both groups were comparable with respect to demographic characteristics age, sex, height, weight, ASA grading. Heart rates, SBP, DBP, MAP, SPO2 at basal value, after intubation, after extubation, and in PACU were similar and comparable in groups C, N1, N2. VAS scores were comparable at 0 min in groups C, N1, N2. At 5,10,15 min VAS scores were lower in control group than group N1 and N2. (P value The mean VAS scores increased in control group after 45 min where as in group N1 scores increased after 75min and in group N2 after 90min. The incidence of PONV was higher in group C compared to groups N1, N2. Statistically significant difference was observed between PONV grade among the three groups (P=0.093) Incidence of respiratory depression was compared in groups C,N1,N2. The P value is 0.0326 which is statistically significant.
{"title":"A randomised control study comparing intravenous fentanyl vs nebulised fentanyl for postoperative pain relief in patients undergoing elective breast surgeries under general anesthesia","authors":"B. T","doi":"10.26611/1015838","DOIUrl":"https://doi.org/10.26611/1015838","url":null,"abstract":"Background: Relief of post operative pain with minimal side effects is a major goal during postanesthesia care. Intravenous fentanyl has been the gold standard for post operative pain relief. Fentanyl is a mu opioid receptor agonist characterised by high potency, rapid onset, short duration of action, lipid solubility and an apparent absence of serious side effects normally associated with opioids. Aim: To compare analgesic efficacy of nebulised fentanyl with intravenous fentanyl for post operative pain relief in patients undergoing breast surgeries under general anesthesia. Objectives: 1. To assess the analgesic efficacy of nebulised fentanyl in comparison to IV fentanyl for post-operative pain relief after breast surgeries. 2. To study Incidence and severity of side effects of fentanyl such as sedation, postoperative nausea and vomiting, respiratory depression, if any. Methodology: After our Hospital Research and Ethics Committee approval and obtaining informed written consent 90 patients aged between 20 and 65 years, belonging to ASA physical status I or II who were scheduled for elective breast surgeries under general anesthesia were included in this randomized control study. The patients were randomly assigned into three groups of 30 patients each to receive either Intravenous fentanyl 1mcg/kg (group C), or nebulised Fentanyl 2mcg/kg (Group N1) and nebulised Fentanyl 3mcg/kg (group N2). Results: These patients in both groups were comparable with respect to demographic characteristics age, sex, height, weight, ASA grading. Heart rates, SBP, DBP, MAP, SPO2 at basal value, after intubation, after extubation, and in PACU were similar and comparable in groups C, N1, N2. VAS scores were comparable at 0 min in groups C, N1, N2. At 5,10,15 min VAS scores were lower in control group than group N1 and N2. (P value The mean VAS scores increased in control group after 45 min where as in group N1 scores increased after 75min and in group N2 after 90min. The incidence of PONV was higher in group C compared to groups N1, N2. Statistically significant difference was observed between PONV grade among the three groups (P=0.093) Incidence of respiratory depression was compared in groups C,N1,N2. The P value is 0.0326 which is statistically significant.","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85449340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Dexamethasone and Dexmedetomidine as adjuvants for TAP block for postoperative analgesia after abdominal hysterectomy under spinal anaesthesia","authors":"Mehul T Suratwala","doi":"10.26611/101521317","DOIUrl":"https://doi.org/10.26611/101521317","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84745809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative study of peripheral nerve stimulator versus ultrasound guided supraclavicular brachial plexus block in upper limb surgeries: Open randomized comparative clinical study","authors":"Bhagavath Kumar Natarajan","doi":"10.26611/10152215","DOIUrl":"https://doi.org/10.26611/10152215","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87987206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative study of supreme laryngeal mask airway versus laryngeal tube undergoing general anesthesia in short surgical procedures","authors":"P. S. Kamat","doi":"10.26611/10152216","DOIUrl":"https://doi.org/10.26611/10152216","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81923330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of sedation levels and adverse effects axillary brachial plexus block with magnesium sulphate and bupivacaine","authors":"P. Sharma","doi":"10.26611/101521314","DOIUrl":"https://doi.org/10.26611/101521314","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73920693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of intravenous nitroglycerine in attenuation of hemodynamic response to tracheal extubation","authors":"Kiran Kumar Suggala","doi":"10.26611/101521315","DOIUrl":"https://doi.org/10.26611/101521315","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"127 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75113972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objectives: Mixing adjuvants with hyperbaric bupivacaine for intrathecal injection is an practice since long time for reducing dose requirement of bupivacaine and prolongation of duration of action. Short acting liophilic opioid fentanyl and selective apha2 agonist dexmedetomidine is used to reduce dose requirement of bupivacaine and its adverse effects and also to prolong postoperative analgesia. The main objective of the study is to compare efficacy of intrathecal adjuvants i.e., dexmedetomidine and fentanyl with hyperbaric bupivacaine to assess postoperative analgesia and side effects Materials and Methods: This prospective, randomized, double blinded and placebo control study was carried out in a tertiary health care centre on 105 patients by randomly allocated into 3 groups and were assigned to receive one of the three intrathecal drugs i.e., Group D (n=35) received mixture of 0.5% hyperbaric bupivacaine (2.5ml) with Dexmedetomidine (5mcg) intrathecally, Group F(n=35) received mixture of 0.5% hyperbaric bupivacaine (2.5ml) with (25mcg) of fentanyl intrathecally and Group B received 0.5% hyperbaric bupivacaine (2.5ml) and 0.5ml normal saline intrathecally. All the solutions were made up to volume of 3ml in a 5ml syringe. Results: The duration of analgesia was significantly longer in Group D (545±61.94) compare to Group F (437.94±43.32) and Group B (263.97±22.88). Conclusion: Dexmedetomidine an adjuvant to bupivacaine (H) found to be very attractive alternative to fentanyl as it provides excellent postoperative analgesia
{"title":"A comparative study of intrathecal dexmedetomidine and fentanyl as adjuvants to bupivacaine to provide prolonged postoperative analgesia","authors":"V. Subhash","doi":"10.26611/10158310","DOIUrl":"https://doi.org/10.26611/10158310","url":null,"abstract":"Background and Objectives: Mixing adjuvants with hyperbaric bupivacaine for intrathecal injection is an practice since long time for reducing dose requirement of bupivacaine and prolongation of duration of action. Short acting liophilic opioid fentanyl and selective apha2 agonist dexmedetomidine is used to reduce dose requirement of bupivacaine and its adverse effects and also to prolong postoperative analgesia. The main objective of the study is to compare efficacy of intrathecal adjuvants i.e., dexmedetomidine and fentanyl with hyperbaric bupivacaine to assess postoperative analgesia and side effects Materials and Methods: This prospective, randomized, double blinded and placebo control study was carried out in a tertiary health care centre on 105 patients by randomly allocated into 3 groups and were assigned to receive one of the three intrathecal drugs i.e., Group D (n=35) received mixture of 0.5% hyperbaric bupivacaine (2.5ml) with Dexmedetomidine (5mcg) intrathecally, Group F(n=35) received mixture of 0.5% hyperbaric bupivacaine (2.5ml) with (25mcg) of fentanyl intrathecally and Group B received 0.5% hyperbaric bupivacaine (2.5ml) and 0.5ml normal saline intrathecally. All the solutions were made up to volume of 3ml in a 5ml syringe. Results: The duration of analgesia was significantly longer in Group D (545±61.94) compare to Group F (437.94±43.32) and Group B (263.97±22.88). Conclusion: Dexmedetomidine an adjuvant to bupivacaine (H) found to be very attractive alternative to fentanyl as it provides excellent postoperative analgesia","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81100138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of duration of postoperative analgesia in orthopedic surgeries done under intrathecal bupivacaine with buprenorphine","authors":"B. Manimaran","doi":"10.26611/10152214","DOIUrl":"https://doi.org/10.26611/10152214","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"71 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91505662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficiency and post-operative sedation in intravenous and intrathecal clonidine in patients undergoing laproscopic assisted vaginal hysterectomy","authors":"Sarav Patel","doi":"10.26611/10152211","DOIUrl":"https://doi.org/10.26611/10152211","url":null,"abstract":"","PeriodicalId":18595,"journal":{"name":"MedPulse International Journal of Anesthesiology","volume":"2002 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88372508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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