Pub Date : 2024-06-01Epub Date: 2023-05-18DOI: 10.23736/S2724-5985.23.03389-2
Michele D Spampinato, Fabio Caputo, Matteo Guarino, Chiara Iantomasi, Francesco Luppi, Marcello Benedetto, Benedetta Perna, Andrea Portoraro, Angelina Passaro, Rinaldo Pellicano, Roberto DE Giorgio
Background: Acute pancreatitis can be a severe disease that significantly impacts patients' quality of life and outcome. The clinical course is variable and predictive scoring systems have a debated role in early prognosis. This study aims to compare the prognostic accuracy of Balthazar, BISAP, HAPS and SOFA scores in the prediction of in-hospital mortality in patients with acute pancreatitis.
Methods: This is a retrospective, single-center cohort study conducted in the Emergency Department of a third-level university hospital. Patients aged >18 years admitted from 1st January 2018 to 31st December 2021 for the first episode of acute pancreatitis were included.
Results: A total of 385 patients (mean age of 65.4 years and 1.8% in-hospital mortality) were studied. Balthazar, BISAP and SOFA scores were significantly higher in patients with in-hospital mortality and AUROCs were equal to 0.95 (95% CI 0.91-0.99, P<0.001), 0.96 (95% CI 0.89-1, P=0.001), 0.91 (95% CI 0.81-1, P=0.001) with no differences among them and absence of in-hospital mortality in patients with HAPS=0.
Conclusions: Our data support the concept that clinical prediction scores can be useful for risk stratification in the Emergency Department. However, no single score has shown superiority in predicting acute pancreatitis-related in-hospital mortality among tested tools.
{"title":"Predicting in-hospital mortality in patients with acute pancreatitis in the ED: a direct, retrospective comparison of four clinical and radiological prognostic scores.","authors":"Michele D Spampinato, Fabio Caputo, Matteo Guarino, Chiara Iantomasi, Francesco Luppi, Marcello Benedetto, Benedetta Perna, Andrea Portoraro, Angelina Passaro, Rinaldo Pellicano, Roberto DE Giorgio","doi":"10.23736/S2724-5985.23.03389-2","DOIUrl":"10.23736/S2724-5985.23.03389-2","url":null,"abstract":"<p><strong>Background: </strong>Acute pancreatitis can be a severe disease that significantly impacts patients' quality of life and outcome. The clinical course is variable and predictive scoring systems have a debated role in early prognosis. This study aims to compare the prognostic accuracy of Balthazar, BISAP, HAPS and SOFA scores in the prediction of in-hospital mortality in patients with acute pancreatitis.</p><p><strong>Methods: </strong>This is a retrospective, single-center cohort study conducted in the Emergency Department of a third-level university hospital. Patients aged >18 years admitted from 1<sup>st</sup> January 2018 to 31<sup>st</sup> December 2021 for the first episode of acute pancreatitis were included.</p><p><strong>Results: </strong>A total of 385 patients (mean age of 65.4 years and 1.8% in-hospital mortality) were studied. Balthazar, BISAP and SOFA scores were significantly higher in patients with in-hospital mortality and AUROCs were equal to 0.95 (95% CI 0.91-0.99, P<0.001), 0.96 (95% CI 0.89-1, P=0.001), 0.91 (95% CI 0.81-1, P=0.001) with no differences among them and absence of in-hospital mortality in patients with HAPS=0.</p><p><strong>Conclusions: </strong>Our data support the concept that clinical prediction scores can be useful for risk stratification in the Emergency Department. However, no single score has shown superiority in predicting acute pancreatitis-related in-hospital mortality among tested tools.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"147-157"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9534492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-05-26DOI: 10.23736/S2724-5985.23.03387-9
Xun Li, Yuanyuan Zhang, Xiefei Hu, Cui Nie, Wei Li, Yan Ding, Huajian Chen
{"title":"A study on urinary tract infections based on a chemotactic microfluidic device.","authors":"Xun Li, Yuanyuan Zhang, Xiefei Hu, Cui Nie, Wei Li, Yan Ding, Huajian Chen","doi":"10.23736/S2724-5985.23.03387-9","DOIUrl":"10.23736/S2724-5985.23.03387-9","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"268-270"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9522873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-16DOI: 10.23736/S2724-5985.23.03466-6
Wenjie Ge, Xiaohui Hu, Jianjie Mao, Pengfei Jia, Jianping Cai
{"title":"Experimental study on the effects of Tongluo Zhibi Tang on articular cartilage and serum IL-1β and TNF-α levels in rabbits with knee osteoarthritis.","authors":"Wenjie Ge, Xiaohui Hu, Jianjie Mao, Pengfei Jia, Jianping Cai","doi":"10.23736/S2724-5985.23.03466-6","DOIUrl":"10.23736/S2724-5985.23.03466-6","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"278-280"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-20DOI: 10.23736/S2724-5985.23.03465-4
Xiaoxue Fu, Mengmeng Song, Rui Zhang, Fang Chen
{"title":"Expression and clinical significance of peripheral blood IL-9 and IL-22 in patients with endometrial cancer.","authors":"Xiaoxue Fu, Mengmeng Song, Rui Zhang, Fang Chen","doi":"10.23736/S2724-5985.23.03465-4","DOIUrl":"10.23736/S2724-5985.23.03465-4","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"245-247"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9655603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-03-21DOI: 10.23736/S2724-5985.23.03308-9
Yuan Zhuang, Jun Yan, Yan Chen, Junlei Chen, Nadia Johnson, Rongqiang Bo, Rongxian An, Fengzhen Yang, Xia Ding
Background: The purpose of this research is to summarize the academic expertise of Professor Lu Zhizheng in the treatment of Chronic Atrophic Gastritis, and to explain his clinical reasoning and common prescriptions in the treatment of CAG.
Methods: Professor Lu's outpatient cases of CAG from January 2008 to December 2021 were selected, and the PageRank algorithm was applied on the FangNet platform to analyze the usage frequencies of herbs, their four natures and five flavors according to Traditional Chinese Medicine, core herbs, and herb clustering patterns, with the goal of summarizing the distinguishing features of Professor Lu's academic and clinical approach to CAG. A total of 170 patients from 252 consultations were included in this study. The prescriptions involved a total of 239 herbs, which occurred a cumulative 4339 times. The herb natures were mainly warm, neutral, and slightly cold, and the herb flavors were predominantly sweet, bitter, and pungent. The channel tropism of the selected herbs primarily targeted the spleen, stomach, and lung meridians. Herb rank analysis showed that 34 herbs, including Gancao, Taizishen, Banxia, Huanglian, Shengjiang, Baizhu, Yiyiren, Maiya, Cangzhu, and Kuxingren, were the driver herbs used by Professor Lu for the treatment of CAG.
Results: Herb-herb co-occurrence/exclusivity analysis revealed 10 sets of frequently used herb pairs; herb cluster analysis yielded 10 herb clusters. These results reflected the emphasis Professor Lu placed on protecting Qi and Yin while clearing damp-heat. Professor Lu Zhizheng utilized dialectics reinforced with flexible thinking in the treatment of CAG, and emphasized that identifying the pathogenesis and addressing the syndrome should be prioritized.
Conclusions: The characteristic treatment strategy aimed to replenish Qi and nourish Yin, clear away damp-heat, and treat CAG patients comprehensively under the guidance of established principles.
{"title":"Research on the experience of National Master of Traditional Chinese Medicine Professor Lu ZhiZheng in treating chronic atrophic gastritis based on data mining technology.","authors":"Yuan Zhuang, Jun Yan, Yan Chen, Junlei Chen, Nadia Johnson, Rongqiang Bo, Rongxian An, Fengzhen Yang, Xia Ding","doi":"10.23736/S2724-5985.23.03308-9","DOIUrl":"10.23736/S2724-5985.23.03308-9","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this research is to summarize the academic expertise of Professor Lu Zhizheng in the treatment of Chronic Atrophic Gastritis, and to explain his clinical reasoning and common prescriptions in the treatment of CAG.</p><p><strong>Methods: </strong>Professor Lu's outpatient cases of CAG from January 2008 to December 2021 were selected, and the PageRank algorithm was applied on the FangNet platform to analyze the usage frequencies of herbs, their four natures and five flavors according to Traditional Chinese Medicine, core herbs, and herb clustering patterns, with the goal of summarizing the distinguishing features of Professor Lu's academic and clinical approach to CAG. A total of 170 patients from 252 consultations were included in this study. The prescriptions involved a total of 239 herbs, which occurred a cumulative 4339 times. The herb natures were mainly warm, neutral, and slightly cold, and the herb flavors were predominantly sweet, bitter, and pungent. The channel tropism of the selected herbs primarily targeted the spleen, stomach, and lung meridians. Herb rank analysis showed that 34 herbs, including Gancao, Taizishen, Banxia, Huanglian, Shengjiang, Baizhu, Yiyiren, Maiya, Cangzhu, and Kuxingren, were the driver herbs used by Professor Lu for the treatment of CAG.</p><p><strong>Results: </strong>Herb-herb co-occurrence/exclusivity analysis revealed 10 sets of frequently used herb pairs; herb cluster analysis yielded 10 herb clusters. These results reflected the emphasis Professor Lu placed on protecting Qi and Yin while clearing damp-heat. Professor Lu Zhizheng utilized dialectics reinforced with flexible thinking in the treatment of CAG, and emphasized that identifying the pathogenesis and addressing the syndrome should be prioritized.</p><p><strong>Conclusions: </strong>The characteristic treatment strategy aimed to replenish Qi and nourish Yin, clear away damp-heat, and treat CAG patients comprehensively under the guidance of established principles.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"158-170"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9141572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of single-incision laparoscopic surgery on operative time, blood loss, time to first flatus, pain, abdominal drainage, and complications in acute appendicitis.","authors":"Zhifeng Xu, Jianghua Pan, Yiren Hu, Xiaochun Tong, Lidong Huang","doi":"10.23736/S2724-5985.23.03464-2","DOIUrl":"10.23736/S2724-5985.23.03464-2","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"266-268"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9994573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-16DOI: 10.23736/S2724-5985.23.03451-4
Weiwei Zhang, Yao Xiao
{"title":"Clinical treatment of acute radiation pneumonitis caused by radiation therapy for lung cancer.","authors":"Weiwei Zhang, Yao Xiao","doi":"10.23736/S2724-5985.23.03451-4","DOIUrl":"10.23736/S2724-5985.23.03451-4","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"270-272"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-16DOI: 10.23736/S2724-5985.23.03467-8
Kaicheng Guo, Qingxiu Wu, Qixiao Zhang, Song Yu
{"title":"Expression and significance of key factors of AMPK-Sirt1 signal pathway in steroid-induced juvenile rabbit model of necrosis femoral head.","authors":"Kaicheng Guo, Qingxiu Wu, Qixiao Zhang, Song Yu","doi":"10.23736/S2724-5985.23.03467-8","DOIUrl":"10.23736/S2724-5985.23.03467-8","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"247-249"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-05-10DOI: 10.23736/S2724-5985.23.03418-6
Jinhua Sun, Xuejun Li, Xiaoqing Wang
{"title":"The advantages and prospects of traditional Chinese medicine in the whole intervention of exogenous cough.","authors":"Jinhua Sun, Xuejun Li, Xiaoqing Wang","doi":"10.23736/S2724-5985.23.03418-6","DOIUrl":"10.23736/S2724-5985.23.03418-6","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"275-278"},"PeriodicalIF":3.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9444216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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