Pub Date : 2017-05-05DOI: 10.19080/tbsnd.2017.01.555552
L. Lakatos
D-penicillamine (DPA) was first recognized as a potential benefit for neonatal hyperbilirubinemia (NHBI) caused by hemolytic diseases or immaturity of UDP-glucuronyltransferase enzyme. During this time there was a remarkedly low incidence of retinopathy of prematurity (ROP) in the infants treated with DPA. Later, our studies were replicated in other institutes in Hungary, Poland, U.S. A., India and Mexico. It is important to note that there was no intolerance or short- or long-term toxicity of the medication, in spite of the fact that in the newborn period DPA was used 10-20 times higher doses than those in adult.
d -青霉胺(DPA)最初被认为对新生儿高胆红素血症(NHBI)有潜在的益处,这些高胆红素血症是由溶血性疾病或udp -葡萄糖醛基转移酶不成熟引起的。在此期间,接受DPA治疗的婴儿的早产儿视网膜病变(ROP)发生率明显降低。后来,我们的研究在匈牙利、波兰、美国、印度和墨西哥的其他研究所得到了重复。值得注意的是,尽管新生儿使用的DPA剂量比成人高10-20倍,但该药物没有不耐受或短期或长期毒性。
{"title":"Use of D-Penicillamine in the Neonatal Hyperbilirubinemias","authors":"L. Lakatos","doi":"10.19080/tbsnd.2017.01.555552","DOIUrl":"https://doi.org/10.19080/tbsnd.2017.01.555552","url":null,"abstract":"D-penicillamine (DPA) was first recognized as a potential benefit for neonatal hyperbilirubinemia (NHBI) caused by hemolytic diseases or immaturity of UDP-glucuronyltransferase enzyme. During this time there was a remarkedly low incidence of retinopathy of prematurity (ROP) in the infants treated with DPA. Later, our studies were replicated in other institutes in Hungary, Poland, U.S. A., India and Mexico. It is important to note that there was no intolerance or short- or long-term toxicity of the medication, in spite of the fact that in the newborn period DPA was used 10-20 times higher doses than those in adult.","PeriodicalId":186900,"journal":{"name":"Theranostics of Brain, Spine & Neural Disorders","volume":"11 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123624894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-17DOI: 10.19080/tbsnd.2017.01.555551
H. Khouzam
With the many recent advances in the pharmacological treatment of psychiatric conditions.The pharmaceutical industry has been vigorous in promoting their products as being very effective intervention for the treatment of mental and psychiatric conditions. Health insurance companies have also been very restrictive in reimbursing psychiatrists for their clinical services if they do not prescribe medications for their patients’ treatment [1]. As a result, many psychiatrists have been pressured to limit their scope of practice to prescribing medications and have been labeled as prescribers as opposed to being physicians who specialize in providing comprehensive and holistic mental health treatment to patients who suffer from psychiatric conditions [2]. The purpose of this commentary is to redefine the role of psychiatrists not just as prescribers but as providers of their time honored calling as holistic healer of mental illness.
{"title":"Psychiatrists as Prescribers Versus Holistic Providers of Mental Health Treatment","authors":"H. Khouzam","doi":"10.19080/tbsnd.2017.01.555551","DOIUrl":"https://doi.org/10.19080/tbsnd.2017.01.555551","url":null,"abstract":"With the many recent advances in the pharmacological treatment of psychiatric conditions.The pharmaceutical industry has been vigorous in promoting their products as being very effective intervention for the treatment of mental and psychiatric conditions. Health insurance companies have also been very restrictive in reimbursing psychiatrists for their clinical services if they do not prescribe medications for their patients’ treatment [1]. As a result, many psychiatrists have been pressured to limit their scope of practice to prescribing medications and have been labeled as prescribers as opposed to being physicians who specialize in providing comprehensive and holistic mental health treatment to patients who suffer from psychiatric conditions [2]. The purpose of this commentary is to redefine the role of psychiatrists not just as prescribers but as providers of their time honored calling as holistic healer of mental illness.","PeriodicalId":186900,"journal":{"name":"Theranostics of Brain, Spine & Neural Disorders","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134023755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}