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Optical and thermal studies on binary liquid crystal mixture 二元液晶混合物的光学和热研究
Pub Date : 2021-04-30 DOI: 10.26524/nr.4.7
Sundaram S, Vasanthi T, Jayaprakash T, Balasubramanian V, Vijayakumar V N
The novel binaryliquid crystal mixture is designed and synthesized from 4-methoxycinnamic acid (MCA) and 4-ethoxycinnamic acid (ECA). Quantum chemical (DFT) calculation for MCA+ECA geometry is optimized by DFT/B3LYP with 6-311G (d, p) basis set and its results are good agreement with experimental data. Fourier-transform infrared spectroscopic(FT-IR) study confirm the presence of intermolecular hydrogen bond in the liquid crystal mixture .The paramorphic changes in nematic phase and thermo-optic properties of binary liquid crystal mixture isanalyzed using polarizing optical microscope (POM) and differential scanning calorimetry (DSC) techniques. A noteworthy observation in the present liquid crystal mixture possesses smectic A phase along with nematic phases. Intermolecular hydrogen bond interaction and it’s stabilization energy of present mixture is studied by natural bond orbital (NBO) analysis. Due to the transition,the presen tliquid crystal mixtur einduces smecticA phase. The molecular properties of presen t binary liquid crystal mixtureis analyzed by HOMO-LUMO and experimental UV-Visible studies. Thermal spanwidth, stability factor and quantum chemical properties of the liquid crystal mixture are calculated.Molecular electrostatic potential, mulliken atomic charge distribution of the optimized MCA+ECA geometry is also reported.
以4-甲氧基肉桂酸(MCA)和4-乙氧基肉桂酸(ECA)为原料,设计合成了新型二元液晶混合物。采用6-311G (d, p)基集的DFT/B3LYP优化了MCA+ECA几何结构的量子化学(DFT)计算,计算结果与实验数据吻合较好。傅里叶变换红外光谱(FT-IR)研究证实了二元液晶混合物中存在分子间氢键,并利用偏光显微镜(POM)和差示扫描量热法(DSC)分析了二元液晶混合物向列相的副晶变化和热光学性质。在目前的液晶混合物中有一个值得注意的观察,它具有近晶A相和向列相。用自然键轨道(NBO)分析方法研究了分子间氢键相互作用及其稳定能。由于这种转变,存在的液晶混合物产生了smecticA相。用HOMO-LUMO和紫外可见实验分析了二元液晶混合物的分子性质。计算了液晶混合物的热展宽、稳定系数和量子化学性质。本文还报道了优化后的MCA+ECA几何结构的分子静电势、mulliken原子电荷分布。
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引用次数: 0
Study of a-C:H thin films deposited by Plasma Immersion Ion Implantation for mechanical and tribological applications 等离子体浸没离子注入沉积a-C:H薄膜的机械和摩擦学研究
Pub Date : 2019-07-14 DOI: 10.26524/NR1933
Péricles Lopes SantAna, R. J. Santos, J. Bortoleto, N. Cruz, E. Rangel, L. V. Santos, Silva Tf
The tribological and mechanical properties of DLC films deposited on the surface of 16MnCr5 steel alloy were investigated. The major concerning of using DLC layers on engine parts are: (i) to reduce friction; (ii) to increase fuel efficiency and to reduce CO2 emission; (iii) to increase hardness of alloy steel. After polished and ultrasonicated, 16MnCr5 substrates were submitted to PIIID procedures in radiofrequency plasmas (13.56 MHz) generated from atmospheres of methane and argon. Excitation power and total gas pressure were kept constant. It was investigated the effect of methane proportion on the microstructure and mechanical properties of the films using the follow techniques: Raman Spectroscopy (for Hydrogen content and microstructure analysis), Ultra Micro-Tribometer (for friction coefficient) and Nanoindentation (hardness evaluation). Raman analysis confirmed DLC character of the films produced, and the proportion of 80% methane and 20% argon resulted to the best performance of mechanical properties of the films owing to the increase of hardness in until ten times, and reducing the friction coefficient to about 0.2. In addition, thickness for these films varied from 165 nm to 206 nm.
研究了沉积在16MnCr5钢合金表面的DLC膜的摩擦学和力学性能。在发动机部件上使用DLC层的主要考虑是:(i)减少摩擦;(ii)提高燃油效率和减少二氧化碳排放;(三)提高合金钢的硬度。经过抛光和超声处理后,16MnCr5衬底在甲烷和氩气产生的射频等离子体(13.56 MHz)中进行PIIID处理。激励功率和总气体压力保持恒定。采用拉曼光谱(用于氢含量和微观结构分析)、超微摩擦计(用于摩擦系数分析)和纳米压痕(硬度评价)等技术研究了甲烷含量对薄膜微观结构和力学性能的影响。Raman分析证实了薄膜的DLC特性,80%的甲烷和20%的氩气使薄膜的硬度提高了10倍,摩擦系数降低到0.2左右,具有最佳的力学性能。此外,这些薄膜的厚度从165 nm到206 nm不等。
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引用次数: 0
Evaluation of Antibacterial and In vivo Wound healing activity of Carbon Dot Nanoparticles 碳点纳米颗粒的抗菌和体内伤口愈合活性评价
Pub Date : 2019-07-12 DOI: 10.26524/NR1932
H. Muktha, R. Sharath, Nagaraju Kottam, S. Srinath, Y Randhir
Treating post-surgical wound is one of the major challenges in the field of medical Science due to the several disadvantages posed by the antibiotics. The antimicrobial and Wound healing activity of metal based nanoparticles were well known, but the effects of carbon dot nanoparticles (C-Dots) are less explored. In the present study a wet chemical method for the synthesis of C-Dots from sucrose, glucose and fructose was developed and they were characterized by UV-Visible, Fluorescent spectroscopic techniques and the pharmaceutical applications such as antibacterial and the wound healing activities were evaluated. The study revealed that the C-Dots synthesized from Sucrose (SCD) and Glucose (GCD) showed potent antibacterial activity against both positive and negative bacterial strains at 12.5µl/ml (0.1 ± 0.003) and Fructose (FCD) at 50 µl/ml (0.1 ± 0.01) compared to the vehicle Control (0.61 ± 0.06). The wound healing of SCD (367.8 ± 15.2) was observed better than the Control (280.8 ± 10.72) and FCD (326.8 ± 9.41). GCD (166.8 ± 10.83) skin tissues indicated best healing as compared to FCD (135.8 ± 8.29), SCD (157.3 ± 16.97) and Control (135.8 ± 8.29). The results suggest that C-Dots applied topically possess wound healing activity and have potential applications as a bacteriostatic agent.
手术后伤口的治疗是医学领域的主要挑战之一,由于抗生素的几个缺点。金属基纳米颗粒的抗菌和伤口愈合活性众所周知,但碳点纳米颗粒(C-Dots)的作用却很少被探索。本研究以蔗糖、葡萄糖和果糖为原料,采用湿化学方法合成C-Dots,并用紫外可见光谱和荧光光谱技术对其进行了表征,并对其在抗菌和伤口愈合等方面的应用进行了评价。结果表明,与对照(0.61±0.06)相比,蔗糖(SCD)和葡萄糖(GCD)合成的C-Dots对阳性和阴性菌株的抑菌活性分别为12.5µl/ml(0.1±0.003)和50µl/ml(0.1±0.01)。SCD组创面愈合(367.8±15.2)优于对照组(280.8±10.72)和FCD组(326.8±9.41)。与FCD(135.8±8.29)、SCD(157.3±16.97)和Control(135.8±8.29)相比,GCD(166.8±10.83)组皮肤组织的愈合效果最好。结果表明,局部应用C-Dots具有伤口愈合活性,具有潜在的抑菌作用。
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引用次数: 5
Nanoparticle synthesis approaches at a glance 纳米粒子合成方法一览
Pub Date : 2019-07-12 DOI: 10.26524/NR1931
Wali Muhammad, Iqra Haleem, N. Ullah, Muhammad Qasim Khan, N. Senthilkumar
Nanotechnology has opened a new era for scientists and engineers to build nanomaterials with diverse applications. Nowadays, nanotechnology plays a vital rolein each and every sector due to its extraordinary physical and chemical properties. It deals with development and synthesis of variety of nanoparticles (NPs), which ranging from 1 to 100 nm. The major approaches used for the synthesis of NPs are top to bottom and bottom to up which mainly included physical, chemical and biological methodologies. This mini review highlights synthesis of NPs through various approaches specifically targeted biological route.
纳米技术为科学家和工程师构建具有多种应用的纳米材料开辟了一个新时代。如今,纳米技术由于其非凡的物理和化学特性,在每个领域都发挥着至关重要的作用。它涉及各种纳米颗粒(NPs)的开发和合成,范围从1到100纳米。NPs合成的主要方法是由上到下和由下到上,主要包括物理、化学和生物方法。这篇综述重点介绍了通过各种途径合成NPs的方法,特别是针对生物途径。
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引用次数: 1
A Review on Nanotechnology Applications in Electric Components 纳米技术在电子元件中的应用综述
Pub Date : 2019-05-30 DOI: 10.26524/NR1924
Salma Zeb, I. Ullah, A. Karim, Wali Muhammad, N. Ullah, Mehmand Khan, W. Komal
Nano science and nanotechnology innovations have shown incredible results in current era. It increases their applications in various fields such as Engineering, Physics, Chemistry and Biology. The development in nanotechnology has replaced conventional concepts. The remarkable performance of nanotechnologycaught the eye of electrical engineers to make reliable and efficient electrical components. Electrical engineers using Nano-concept and make Nano-structured valueadded products with high superior qualities. This review climaxes the concept of nanotechnology in various electrical components such as in nanowires, insulators, transformers and dielectric fluids with possible future prospects
纳米科学和纳米技术创新在当今时代已经显示出令人难以置信的成果。它增加了它们在工程、物理、化学和生物等各个领域的应用。纳米技术的发展已经取代了传统的概念。纳米技术的卓越性能引起了电气工程师的注意,以制造可靠和高效的电气元件。电气工程师利用纳米概念,制造出具有高品质的纳米结构增值产品。本文综述了纳米技术在纳米线、绝缘体、变压器和介电流体等各种电子元件中的应用,并展望了纳米技术的发展前景
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引用次数: 6
Silver Nanoparticle-Mediated Cellular Responses in Human Keratinocyte Cell Line HaCaT in Vitro 纳米银介导的人角质形成细胞系HaCaT的细胞反应
Pub Date : 2019-04-26 DOI: 10.26524/NR1921
K. Habas, L. Shang
The interactions between cells and nanoparticles has been the focus of recent research in the area. The effects of AgNPs on skin cell lines for further potential biological applications are highlighted. This study aimed to investigate the mechanism of cytotoxic and genotoxic effects of AgNPs nanoparticles on human skin keratinocytes (HaCaT). Genocytotoxic effects of AgNPs was assessed using changes in various cellular parameters of HaCaT cells involving viability, superoxide anion radical production, lactate dehydrogenase release and the levels of the antioxidant enzymes, namely, Catalase, Glutathione peroxidase (GPX) and Superoxide Dismutase (SOD). Superoxide anion was detected using nitroblue tetrazolium NBT reduction assay. LDH levels was evaluated using the standard kit, and activity of antioxidant enzymes such as catalase (CAT), glutathione peroxidase 1 (GPX-1) and superoxide dismutase 1 (SOD-1) were quantified using qPCR. Our results indicated that AgNPs caused severe HaCaT oxidative damage, accompanied by increased the production of superoxide anion levels as well as significant decrease in endogenous antioxidant enzyme of SOD, CAT, GPX expression involved in HaCat cells in vitro. Our study suggests that AgNPs exposure increased oxidative stress levels. Moreover; the low cytotoxic effect observed on human HaCaT keratinocytes suggested that these nano-compounds have a potential toxic effect at the skin level only after long-term exposure.
细胞与纳米颗粒之间的相互作用是近年来该领域研究的焦点。重点介绍了AgNPs对皮肤细胞系的影响及其潜在的生物学应用。本研究旨在探讨AgNPs纳米颗粒对人皮肤角质形成细胞(HaCaT)的细胞毒性和基因毒性作用机制。通过改变HaCaT细胞的各种细胞参数,包括活力、超氧阴离子自由基产生、乳酸脱氢酶释放和抗氧化酶,即过氧化氢酶、谷胱甘肽过氧化物酶(GPX)和超氧化物歧化酶(SOD)的水平,评估AgNPs的细胞毒性作用。采用硝基蓝四氮唑NBT还原法检测超氧阴离子。采用标准试剂盒检测LDH水平,qPCR检测过氧化氢酶(CAT)、谷胱甘肽过氧化物酶1 (GPX-1)、超氧化物歧化酶1 (SOD-1)等抗氧化酶活性。我们的研究结果表明,AgNPs在体外引起HaCaT细胞严重的氧化损伤,伴有超氧阴离子水平的产生增加,内源性抗氧化酶SOD、CAT、GPX的表达显著降低。我们的研究表明AgNPs暴露会增加氧化应激水平。此外;观察到的对人HaCaT角质形成细胞的低细胞毒性作用表明,这些纳米化合物只有在长期接触后才会在皮肤水平上产生潜在的毒性作用。
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引用次数: 5
Structural and Electrical Properties of ZnO Varistor with Different Particle Size for Initial Oxides Materials 初始氧化物材料中不同粒径氧化锌压敏电阻的结构和电性能
Pub Date : 2019-04-26 DOI: 10.26524/NR1923
S. A. Amin
We report here structural, electrical and dielectric properties of ZnO varistors prepared with two different particle sizes for initial starting oxides materials (5 µm and 200 nm). It is found that the particle size of ZnO does not influence the hexagonal wurtzite structure of ZnO, while the lattice parameters, crystalline diameter, grain size and Zn-O bond length are affected. The nonlinear coefficient, breakdown field and barrier height are decreased from 18.6, 1580 V/cm and 1.153 eV for ZnO micro to 410 V/cm, 7.26 and 0.692 eV for ZnO nano.  While, residual voltage and electrical conductivity of upturn region are increased from 2.08 and 2.38x10-5 (Ω.cm)-1 to 4.55 and 3.03x10-5 (Ω.cm)-1. The electrical conductivity increases by increasing temperature for both varistors, and it is higher for ZnO nano than that of ZnO micro.  The character of electrical conductivity against temperature is divided into three different regions over the temperature intervals as follows; (300 K ≤ T ≤ 420 K), (420 K ≤ T ≤ 580 K) and (580 K ≤ T ≤ 620 K), respectively. The activation energy is increased in the first region from 0.141 eV for ZnO micro to 0.183 eV for ZnO nano and it is kept nearly constant in the other two regions. On the other hand, the average conductivity deduced through dielectric measurements is increased from 2.54x10-7 (Ω.cm)-1 for ZnO micro to 49x10-7 (Ω.cm)-1. Similar behavior is obtained for the conductivities of grains and grain boundaries. The dielectric constant decreases as the frequency increases for both varistors, and it is higher for ZnO nano than that of ZnO micro. These results are discussed in terms of free excited energy and strength of link between grains of these varistors.
本文报道了用两种不同粒径的初始氧化物材料(5µm和200 nm)制备ZnO压敏电阻的结构、电学和介电性能。研究发现,ZnO的粒径对ZnO的六方纤锌矿结构没有影响,而晶格参数、晶粒直径、晶粒尺寸和Zn-O键长受到影响。非线性系数、击穿场和势垒高度分别从微ZnO的18.6、1580 V/cm和1.153 eV降低到纳米ZnO的410 V/cm、7.26和0.692 eV。而上向区残余电压和电导率由2.08和2.38x10-5 (Ω.cm)-1增加到4.55和3.03x10-5 (Ω.cm)-1。两种压敏电阻的电导率均随温度升高而升高,且纳米ZnO的电导率高于微ZnO。电导率随温度变化的特性在温度区间内分为三个不同的区域,如下所示:(300 K≤T≤420 K)、(420 K≤T≤580 K)和(580 K≤T≤620 K)。第一个区域的活化能从微氧化锌的0.141 eV增加到纳米氧化锌的0.183 eV,而其他两个区域的活化能基本保持不变。另一方面,通过介电测量得出的ZnO微晶的平均电导率从2.54x10-7 (Ω.cm)-1增加到49x10-7 (Ω.cm)-1。晶粒的电导率和晶界也得到了类似的结果。两种压敏电阻的介电常数均随频率的增加而减小,且纳米ZnO的介电常数高于微ZnO。这些结果从自由激发能和晶粒间连接强度的角度进行了讨论。
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引用次数: 5
Recent Nanotechnological Approaches on Capturing, Isolating, and Identifying Circulating Tumor Cells 捕获、分离和鉴定循环肿瘤细胞的最新纳米技术方法
Pub Date : 2019-04-26 DOI: 10.26524/NR1922
A. B. Sözmen, Ahu Arslan Yildiz
Nanotechnological approaches are the latest modality for early stage detection of cancer. The need of rapid, non-invasive, patient specific, and informative techniques in cancer diagnostics lead to the utilization of nanotechnology, microfluidics, and lab-on-a-chip platforms for liquid biopsy, and the developments through these technologies increased the knowledge also for case specific applications. In this review, nanotechnology-based methodologies that are developed in the last decade for cancer diagnostics are investigated and are discussed under four main categories for the purpose of simplification as; nanochip based, nanofilm based, magnetic nanomaterial-based methods, and combinational utilization of multiple methodologies. We suggest a combinational approach on device development with an aim of producing a compact, cost effective, rapid, sensitive, and non-invasive diagnostic device as a conclusion of literature review.
纳米技术方法是癌症早期检测的最新方式。对快速、非侵入性、患者特异性和信息丰富的癌症诊断技术的需求导致了纳米技术、微流体和芯片实验室平台在液体活检中的应用,通过这些技术的发展也增加了病例特异性应用的知识。在这篇综述中,基于纳米技术的方法是在过去十年中发展起来的癌症诊断进行了调查,并在四个主要类别下进行了讨论,以简化为:基于纳米芯片的、基于纳米膜的、基于磁性纳米材料的方法,以及多种方法的组合利用。作为文献综述的结论,我们建议在设备开发上采用组合方法,目的是生产一种紧凑、经济、快速、敏感和非侵入性的诊断设备。
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引用次数: 0
Multitasking Herbal Nanomedicine 多任务草药纳米药物
Pub Date : 2019-02-28 DOI: 10.26524/NR1914
Hendry Izaac El
A frontier review from creative research works on nanotechnology and nanomedicine is presented in a systematic explanation. Based on multitasking healing system of herbal medicine identified in the beginning using a simple theoretical physics works, and the natural product of herbal medicine, the step by step guidance to develop important herbal nanomedicine is then enlightened. Such important herbal medicines with their unique and multitasking healing system were studied by implementing five point behavior parameters: (1). Optical property (OP), (2). Electronics and magnetics character (EMC), (3). Mechanical behavior (MB), (4). Chemical possessions (CP), and (5). Quantum movables (QM). Finally, the detail of output herbal nanomedicine is briefly elucidated. Our findings show that herbal nanomedicine are very promising for multitasking healing system which is absolutely different from normal synthetic drug which heals one target with one medicine.
从纳米技术和纳米医学的创新研究工作的前沿综述进行了系统的解释。本文首先用简单的理论物理原理确定了草药的多任务治疗系统,并对草药的天然产物进行了阐述,进而对逐步指导开发重要的草药纳米药物进行了启示。这些重要的草药具有独特的多任务治疗系统,通过实施五点行为参数进行研究:(1)光学性质(OP),(2)电子和磁性(EMC),(3)力学行为(MB),(4)化学性质(CP),(5)量子可动性(QM)。最后,简要阐述了中药纳米输出的具体情况。我们的研究结果表明,草药纳米药物在多任务治疗系统中非常有前景,这与普通合成药物用一种药物治疗一个靶点是完全不同的。
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引用次数: 4
Structural, Optical & Magnetic Properties of (Fe, Al) Co-Doped Zinc Oxide Nanoparticles (Fe, Al)共掺杂氧化锌纳米颗粒的结构、光学和磁性能
Pub Date : 2019-02-28 DOI: 10.26524/NR1912
P. Swapna, S. V. Reddy
Pure and (Fe, Al) co-doped ZnO nanopowders are prepared via co-precipitation method constructively with PEG as capping agent at room temperature (RT). We kept the aluminum concentration as constant at 5 mol% by altering the iron concentration from one to three mol%. After the finishing point of synthesis, the powders are cautiously subjected to various characterizations for instance XRD, Raman, SEM through EDS, TEM, PL, UV-Vis-NIR and VSM, to analyze the properties of structural, morphological, optical and magnetic. XRD analysis reveals, all the nanopowder samples acquire hexagonal wurtzite structure by the nonexistence of secondary peaks involving to aluminum or iron. This reveals the well dissolving of aluminum and iron in to Zinc Oxide host lattice. The literal size of nanocrystallites is evaluated through TEM pictures, which are approximately corroborated by the XRD calculations. The nanostructures morphology is found through SEM illustrations, and the spectrum of EDS shows that no impurities are existence other than iron and aluminum. Optical properties are deliberated by the PL spectrum and UV-Vis-NIR spectrum; all the powder samples encompass defect associated peaks over the visible range. Magnetic properties are evaluated using VSM and all the co-doped samples contain the Ferromagnetic nature except pristine Zinc Oxide.
以聚乙二醇为封盖剂,采用共沉淀法在室温下制备了纯氧化锌和(Fe, Al)共掺杂氧化锌纳米粉体。我们把铁的浓度从1摩尔%改变为3摩尔%,使铝的浓度保持在5摩尔%不变。合成完成后,对粉体进行XRD、Raman、SEM - EDS、TEM、PL、UV-Vis-NIR、VSM等多种表征,分析粉体的结构、形貌、光学、磁性等性能。XRD分析表明,所有纳米粉体样品均具有六方纤锌矿结构,不存在涉及铝或铁的二次峰。这表明铝和铁在氧化锌基体晶格中溶解良好。通过TEM图像对纳米晶的尺寸进行了评价,并与XRD计算结果进行了近似验证。SEM图显示了纳米结构的形貌,EDS谱显示除了铁和铝外没有其他杂质存在。光学性质由PL光谱和UV-Vis-NIR光谱来考虑;所有粉末样品在可见范围内都包含缺陷相关峰。磁性能利用VSM进行评估,除原始氧化锌外,所有共掺杂样品都具有铁磁性。
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引用次数: 5
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