Pub Date : 2023-06-01DOI: 10.3103/s0891416823020076
S. A. Paradnikova, V. G. Druzhinin, E. D. Baranova, P. S. Demenkov, A.V. Larionov
{"title":"Specifics of the Taxonomic Composition of Bacterial Microflora in the Respiratory Microbiome of Patients with Chronic Dust Bronchitis","authors":"S. A. Paradnikova, V. G. Druzhinin, E. D. Baranova, P. S. Demenkov, A.V. Larionov","doi":"10.3103/s0891416823020076","DOIUrl":"https://doi.org/10.3103/s0891416823020076","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010093
N. Smirnova, D. A. Rybal’chenko, N. A. Plekhanov, Yu. V. Lozovsky, A. Fedorov, V. Kutyrev
{"title":"New Genetic Variants of the Cholera Agent and Their Distribution in Endemic Countries and Russia","authors":"N. Smirnova, D. A. Rybal’chenko, N. A. Plekhanov, Yu. V. Lozovsky, A. Fedorov, V. Kutyrev","doi":"10.3103/S0891416823010093","DOIUrl":"https://doi.org/10.3103/S0891416823010093","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82971734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010020
E. Avdiusheva, D. N. Luchinin, N. Borodai, A. Antonov, D. Ustinov, E. Molchanova, I. Shpak, D. Viktorov, A. Toporkov
{"title":"The First Detection of Ebinur Lake Virus (Orthobunyavirus, Peribunyaviridae) in Russia","authors":"E. Avdiusheva, D. N. Luchinin, N. Borodai, A. Antonov, D. Ustinov, E. Molchanova, I. Shpak, D. Viktorov, A. Toporkov","doi":"10.3103/S0891416823010020","DOIUrl":"https://doi.org/10.3103/S0891416823010020","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89785170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S089141682301007X
T. Malivanova, T. Astrelina, I. Kobzeva, V. Nikitina, Y. Suchkova, A. S. Ostashkin, D. Usupzhanova, E. I. Dobrovolskaya, V. Brunchukov, A. Rastorgueva, E. E. Lomonosova, E. Lubaeva, E. Y. Kretova, N. G. Stepanyants, M. Sukhova, A. Samoilov
{"title":"Autoimmune Haplotype AH8.1 Normalizes the Level of Tumor Necrosis Factor in the Blood Sera of Breast-Cancer Patients","authors":"T. Malivanova, T. Astrelina, I. Kobzeva, V. Nikitina, Y. Suchkova, A. S. Ostashkin, D. Usupzhanova, E. I. Dobrovolskaya, V. Brunchukov, A. Rastorgueva, E. E. Lomonosova, E. Lubaeva, E. Y. Kretova, N. G. Stepanyants, M. Sukhova, A. Samoilov","doi":"10.3103/S089141682301007X","DOIUrl":"https://doi.org/10.3103/S089141682301007X","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86252990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010032
Elmira Babakanrad, T. Mohammadian, D. Esmaeili, P. Behzadi
{"title":"Determining the Antibacterial Effect of Recombinant CpsA-CpsC-L-ACAN Fusion Peptide against E. coli and Staphylococcus aureus","authors":"Elmira Babakanrad, T. Mohammadian, D. Esmaeili, P. Behzadi","doi":"10.3103/S0891416823010032","DOIUrl":"https://doi.org/10.3103/S0891416823010032","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73715870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010081
T. Sharov, D. Viktorov, A. Toporkov
{"title":"Proteomic Analysis in Microbiology","authors":"T. Sharov, D. Viktorov, A. Toporkov","doi":"10.3103/S0891416823010081","DOIUrl":"https://doi.org/10.3103/S0891416823010081","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86349779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010044
Lizeth Guardado-Valdivia, Alejandra Chacón-López, José Luis Hernández-Flores, L. Xoca-Orozco, E. Montalvo-González, Selene Aguilera
{"title":"In Pseudomonas syringae pv. phaseolicola NPS3121 the Regulator HrpL is Required for Siderophore Biosynthesis","authors":"Lizeth Guardado-Valdivia, Alejandra Chacón-López, José Luis Hernández-Flores, L. Xoca-Orozco, E. Montalvo-González, Selene Aguilera","doi":"10.3103/S0891416823010044","DOIUrl":"https://doi.org/10.3103/S0891416823010044","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81547533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S0891416823010068
A. L. Klass, N. Krylova, A. Lysenko, I. Vlasov, M. Maslova, G. I. Salagaev, E. Kovalevskaya, N. Poteshkina, M. Shadrina, P. Slominsky, E. V. Filatova
{"title":"Prevalence of MYBPC3 Gene Mutations in Russian Patients with Hypertrophic Cardiomyopathy","authors":"A. L. Klass, N. Krylova, A. Lysenko, I. Vlasov, M. Maslova, G. I. Salagaev, E. Kovalevskaya, N. Poteshkina, M. Shadrina, P. Slominsky, E. V. Filatova","doi":"10.3103/S0891416823010068","DOIUrl":"https://doi.org/10.3103/S0891416823010068","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78948407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.3103/S089141682301010X
S. Vasilieva, N. V. Alekseeva, Y. Romanova, A. F. Vanin
{"title":"Nitrosonium Cation NO^+ Inhibits Nitric-Oxide Functions in the Regulation of Pseudomonas aeruginosa Biofilm Formation","authors":"S. Vasilieva, N. V. Alekseeva, Y. Romanova, A. F. Vanin","doi":"10.3103/S089141682301010X","DOIUrl":"https://doi.org/10.3103/S089141682301010X","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87580858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-06-11DOI: 10.3103/S0891416823010111
O L Voronina, N N Ryzhova, E I Aksenova, M S Kunda, A V Kutuzova, T I Karpova, Yu K Yushina, I S Tartakovsky
The safety of food production as concerns Listeria is the key to the sanitary wellbeing of manufactured products. Molecular-genetic methods for the analysis of Listeria, including whole-genome sequencing, are effective in monitoring persistent contaminants and in the epidemic investigation of cases of foodborne infections. They have been adopted in the European Union, United States, and Canada. In Russia, multilocus and whole-genome sequencing has proven itself in the analysis of clinical food isolates and Listeria from the environment. The objective of the study was molecular-genetic characterization of Listeria detected in the industrial environment of meat processing. To characterize the Listeria isolates, microbiological methods were used according to GOST (State Standard) 32031-2012, as well as multilocus sequencing, including the analysis of seven housekeeping genes and four virulence genes, as well as whole-genome sequencing. In swabs that were positive for the presence of Listeria spp. taken at two meat-processing plants in Moscow, Listeria monocytogenes constituted 81% and L. welshimeri 19%. The predominant genotype (Sequence Type, ST) of L. monocytogenes was ST8. The variety was supplemented with ST321, ST121, and ST2330 (CC9 (Clonal Complex 9)). L. welshimeri, which prevailed in the second production, was represented by ST1050 and ST2331. The genomic characteristics of L. welshimeri isolates confirmed that they have high adaptive capabilities both as concerns production conditions (including resistance to disinfectants) and the metabolic peculiarities of the gastrointestinal tract of animals. L. monocytogenes CC9 and CC121 are also correlated with food production in other countries. However, L. monocytogenes CC8 and CC321 can cause invasive listeriosis. The concordance in the internalin profile of the ST8 isolates from the industrial environment with the clinical isolates ST8 and ST2096 (CC8) is a cause for concern. The study showed the effectiveness of molecular-genetic methods in determining the diversity of Listeria detected in the production environment of meat processing, and laid the foundation for monitoring of persistent contaminants.
{"title":"Genetic Diversity of <i>Listeria</i> Detected in the Production Environment of Meat Processing.","authors":"O L Voronina, N N Ryzhova, E I Aksenova, M S Kunda, A V Kutuzova, T I Karpova, Yu K Yushina, I S Tartakovsky","doi":"10.3103/S0891416823010111","DOIUrl":"10.3103/S0891416823010111","url":null,"abstract":"<p><p>The safety of food production as concerns <i>Listeria</i> is the key to the sanitary wellbeing of manufactured products. Molecular-genetic methods for the analysis of <i>Listeria</i>, including whole-genome sequencing, are effective in monitoring persistent contaminants and in the epidemic investigation of cases of foodborne infections. They have been adopted in the European Union, United States, and Canada. In Russia, multilocus and whole-genome sequencing has proven itself in the analysis of clinical food isolates and <i>Listeria</i> from the environment. The objective of the study was molecular-genetic characterization of <i>Listeria</i> detected in the industrial environment of meat processing. To characterize the <i>Listeria</i> isolates, microbiological methods were used according to <i>GOST</i> (State Standard) 32031-2012, as well as multilocus sequencing, including the analysis of seven housekeeping genes and four virulence genes, as well as whole-genome sequencing. In swabs that were positive for the presence of <i>Listeri</i>a spp. taken at two meat-processing plants in Moscow, <i>Listeria monocytogenes</i> constituted 81% and <i>L. welshimeri</i> 19%. The predominant genotype (Sequence Type, ST) of <i>L. monocytogenes</i> was ST8. The variety was supplemented with ST321, ST121, and ST2330 (CC9 (Clonal Complex 9)). <i>L. welshimeri</i>, which prevailed in the second production, was represented by ST1050 and ST2331. The genomic characteristics of <i>L. welshimeri</i> isolates confirmed that they have high adaptive capabilities both as concerns production conditions (including resistance to disinfectants) and the metabolic peculiarities of the gastrointestinal tract of animals. <i>L. monocytogenes</i> CC9 and CC121 are also correlated with food production in other countries. However, <i>L. monocytogenes</i> CC8 and CC321 can cause invasive listeriosis. The concordance in the internalin profile of the ST8 isolates from the industrial environment with the clinical isolates ST8 and ST2096 (CC8) is a cause for concern. The study showed the effectiveness of molecular-genetic methods in determining the diversity of <i>Listeria</i> detected in the production environment of meat processing, and laid the foundation for monitoring of persistent contaminants.</p>","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9654997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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