Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_72_22
M. Duraimurugan, N. Kumar, R. Karthikeyan, S. Balamurugan, Udhayabashkaran Kadirvelu
Background: Diabetes is an alarming health problem affecting more than half a billion people globally. Diabetes is one of the most psychologically demanding illnesses and is frequently associated with anxiety and depression. The present study aimed to estimate the prevalence of depression and anxiety among diabetic patients and comparison of mental health assessment tools among diabetic and nondiabetic participants. Methodology: A comparative study of 80 diabetic patients attending the diabetology outpatient department and 80 age-matched nondiabetic attendees/relatives of patients attending the medicine outpatient department were randomly selected after fulfilling inclusion and exclusion criteria. After confirming their disease status, informed consent was obtained. Data were collected using a pretested questionnaire, mini international neuropsychiatric interview scale, beck depression inventory (BDI) for depression, and Hamilton Rating Scale for Anxiety scale (HAM-A) for anxiety. Results: Majority of the study participants in both groups (n = 35, 43.8%) were of 46–50 years old. About 52.5% of diabetic and 17.5% of nondiabetic participants were having depression and 51.3% of diabetic and 18.3% of nondiabetics were having anxiety as per BDI and HAM-A scores, respectively. Although major differences in sociodemographic variables such as socioeconomic class, gender, and place of residence, etc., between the two groups, it was not statistically significant. Conclusion: The present study shows depression and anxiety were more common among diabetic patients than nondiabetic participants. The risk for depression and anxiety is more among male patients, urban population, and those in low-socioeconomic status.
{"title":"A comparative study to assess depression and anxiety in Type 2 diabetes mellitus patients in a tertiary care hospital","authors":"M. Duraimurugan, N. Kumar, R. Karthikeyan, S. Balamurugan, Udhayabashkaran Kadirvelu","doi":"10.4103/mjmsr.mjmsr_72_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_72_22","url":null,"abstract":"Background: Diabetes is an alarming health problem affecting more than half a billion people globally. Diabetes is one of the most psychologically demanding illnesses and is frequently associated with anxiety and depression. The present study aimed to estimate the prevalence of depression and anxiety among diabetic patients and comparison of mental health assessment tools among diabetic and nondiabetic participants. Methodology: A comparative study of 80 diabetic patients attending the diabetology outpatient department and 80 age-matched nondiabetic attendees/relatives of patients attending the medicine outpatient department were randomly selected after fulfilling inclusion and exclusion criteria. After confirming their disease status, informed consent was obtained. Data were collected using a pretested questionnaire, mini international neuropsychiatric interview scale, beck depression inventory (BDI) for depression, and Hamilton Rating Scale for Anxiety scale (HAM-A) for anxiety. Results: Majority of the study participants in both groups (n = 35, 43.8%) were of 46–50 years old. About 52.5% of diabetic and 17.5% of nondiabetic participants were having depression and 51.3% of diabetic and 18.3% of nondiabetics were having anxiety as per BDI and HAM-A scores, respectively. Although major differences in sociodemographic variables such as socioeconomic class, gender, and place of residence, etc., between the two groups, it was not statistically significant. Conclusion: The present study shows depression and anxiety were more common among diabetic patients than nondiabetic participants. The risk for depression and anxiety is more among male patients, urban population, and those in low-socioeconomic status.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49417848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_4_23
E. Ajaykumar, Thilak Anjanappa, Komera Sunanda, Y. Pranaya
Background: A major global health concern in the 21st century is diabetes. The prevalence of diabetes in India is 8.3%, and 647,831 deaths were related to diabetes in India. Medical students tend to have a sedentary lifestyle due to academic demands, which makes them more prone to noncommunicable diseases such as diabetes. The study was conducted to assess the risk of type 2 diabetes mellitus and to determine the factors associated with the risk of diabetes among medical students at a medical college in Andhra Pradesh. Materials and Methods: A cross-sectional study was conducted among 277 medical students in a medical college in Andhra Pradesh. The Finnish Diabetes Risk Score scale was used to assess diabetes risk, and data were collected through online mode using Google Forms after taking informed consent. Descriptive statistics and the Chi-square test were used, and P < 0.05 was considered statistically significant. Results: The risk of acquiring diabetes in the next 10 years was slightly elevated in 46 (16.6%) female students, 7 (2.5%) male students, and moderate risk in 4 (1.4%) female students. There was a significant association between diabetes risk and body mass index, physical activity >30 min, eating veg/fruits daily, history of high blood glucose, and history of diabetes in the family. Conclusion: According to the study, one-fifth of students had a slightly elevated or moderate risk of diabetes in the next 10 years.
{"title":"Diabetes risk assessment among medical students of a medical college in Andhra Pradesh: A cross-sectional study","authors":"E. Ajaykumar, Thilak Anjanappa, Komera Sunanda, Y. Pranaya","doi":"10.4103/mjmsr.mjmsr_4_23","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_4_23","url":null,"abstract":"Background: A major global health concern in the 21st century is diabetes. The prevalence of diabetes in India is 8.3%, and 647,831 deaths were related to diabetes in India. Medical students tend to have a sedentary lifestyle due to academic demands, which makes them more prone to noncommunicable diseases such as diabetes. The study was conducted to assess the risk of type 2 diabetes mellitus and to determine the factors associated with the risk of diabetes among medical students at a medical college in Andhra Pradesh. Materials and Methods: A cross-sectional study was conducted among 277 medical students in a medical college in Andhra Pradesh. The Finnish Diabetes Risk Score scale was used to assess diabetes risk, and data were collected through online mode using Google Forms after taking informed consent. Descriptive statistics and the Chi-square test were used, and P < 0.05 was considered statistically significant. Results: The risk of acquiring diabetes in the next 10 years was slightly elevated in 46 (16.6%) female students, 7 (2.5%) male students, and moderate risk in 4 (1.4%) female students. There was a significant association between diabetes risk and body mass index, physical activity >30 min, eating veg/fruits daily, history of high blood glucose, and history of diabetes in the family. Conclusion: According to the study, one-fifth of students had a slightly elevated or moderate risk of diabetes in the next 10 years.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45912746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_47_22
Garyll Ryan Tariang Blah, RS Tonk
Background and Aim: Serum ferritin is a marker of hepatic inflammation and has been studied to predict mortality in decompensated cirrhotics. No study has been done to evaluate ferritin as an independent marker of liver disease severity. We investigated whether serum ferritin levels can be correlated with Child–Pugh and Model for End-stage Liver Disease (MELD) scores. Materials and Methods: Seventy-five patients fulfilling the criteria were included and a cross-sectional observational study was done. Results: Seventy-five patients (68 males and 7 females) were evaluated. Serum ferritin levels were found to be significantly elevated in patients having higher Child–Pugh and MELD scores and showed a significant correlation with Child–Pugh score (P = 0.001) and MELD score (P = 0.027). On univariate analysis, serum ferritin, bilirubin, international normalized ratio, ascites, and sodium were found to be significantly associated with severity of liver disease. On multivariate analysis, however, serum ferritin was not found to have a significant association with severity of liver disease. AUROC was also determined which showed that serum ferritin had relatively poor discriminative ability. Conclusion: Elevation of serum ferritin is prevalent in chronic liver disease (CLD). In patients of CLD, severity is associated with a higher serum ferritin level. In future, a study may be designed, to obtain a prognostic model in incorporating serum ferritin into MELD similar to MELD-Na scoring system.
{"title":"Correlation of serum ferritin with severity of liver disease","authors":"Garyll Ryan Tariang Blah, RS Tonk","doi":"10.4103/mjmsr.mjmsr_47_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_47_22","url":null,"abstract":"Background and Aim: Serum ferritin is a marker of hepatic inflammation and has been studied to predict mortality in decompensated cirrhotics. No study has been done to evaluate ferritin as an independent marker of liver disease severity. We investigated whether serum ferritin levels can be correlated with Child–Pugh and Model for End-stage Liver Disease (MELD) scores. Materials and Methods: Seventy-five patients fulfilling the criteria were included and a cross-sectional observational study was done. Results: Seventy-five patients (68 males and 7 females) were evaluated. Serum ferritin levels were found to be significantly elevated in patients having higher Child–Pugh and MELD scores and showed a significant correlation with Child–Pugh score (P = 0.001) and MELD score (P = 0.027). On univariate analysis, serum ferritin, bilirubin, international normalized ratio, ascites, and sodium were found to be significantly associated with severity of liver disease. On multivariate analysis, however, serum ferritin was not found to have a significant association with severity of liver disease. AUROC was also determined which showed that serum ferritin had relatively poor discriminative ability. Conclusion: Elevation of serum ferritin is prevalent in chronic liver disease (CLD). In patients of CLD, severity is associated with a higher serum ferritin level. In future, a study may be designed, to obtain a prognostic model in incorporating serum ferritin into MELD similar to MELD-Na scoring system.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48789619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_81_22
G. Dharmalingam, Kasthuri Lingam, kannan.R Dinesh, Kannika Parameshari, K. Murugan
Background: Improving child survival still remains challenging for most of the developing countries like India. Leading causes of under-five mortality such as pneumonia and diarrhea can be prevented by ensuring good water, sanitation, and hygiene (WASH) practices. This study aimed to assess the WASH practices of caregivers of under-five children in a coastal area of Tamil Nadu in South India. Materials and Methods: This study was conducted as a community-based cross-sectional study among primary caregivers of under-five children in Thoothukudi district, Tamil Nadu. Caregivers accompanying under-five children in Threspuram and Mullakadu Primary Health Centers were interviewed. A semi-structured interview-based questionnaire was used to assess their WASH practices. Data were analyzed using the Statistical Package for the Social Sciences (SPSS). Results: The median WASH score was found to be 16 with an interquartile range of 6.5. Nearly 35% of the caregivers did not do anything to purify drinking water. Only less than three-fourths of the study population followed proper water storage practices. Only 7.2% of caregivers always washed their hands after defecation. The WASH score increased significantly with the education of the caregiver (P < 0.001). Conclusion: WASH practices were mostly poor for under-five children with male caregivers and caregivers with higher age and lower educational status.
{"title":"Water, sanitation, and hygiene practices of caregivers of under-five children in a coastal area of South India","authors":"G. Dharmalingam, Kasthuri Lingam, kannan.R Dinesh, Kannika Parameshari, K. Murugan","doi":"10.4103/mjmsr.mjmsr_81_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_81_22","url":null,"abstract":"Background: Improving child survival still remains challenging for most of the developing countries like India. Leading causes of under-five mortality such as pneumonia and diarrhea can be prevented by ensuring good water, sanitation, and hygiene (WASH) practices. This study aimed to assess the WASH practices of caregivers of under-five children in a coastal area of Tamil Nadu in South India. Materials and Methods: This study was conducted as a community-based cross-sectional study among primary caregivers of under-five children in Thoothukudi district, Tamil Nadu. Caregivers accompanying under-five children in Threspuram and Mullakadu Primary Health Centers were interviewed. A semi-structured interview-based questionnaire was used to assess their WASH practices. Data were analyzed using the Statistical Package for the Social Sciences (SPSS). Results: The median WASH score was found to be 16 with an interquartile range of 6.5. Nearly 35% of the caregivers did not do anything to purify drinking water. Only less than three-fourths of the study population followed proper water storage practices. Only 7.2% of caregivers always washed their hands after defecation. The WASH score increased significantly with the education of the caregiver (P < 0.001). Conclusion: WASH practices were mostly poor for under-five children with male caregivers and caregivers with higher age and lower educational status.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47505543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_84_22
R. Mungmunpuntipantip, V. Wiwanitkit
{"title":"Orthospychiatry issue for COVID-19 lockdown","authors":"R. Mungmunpuntipantip, V. Wiwanitkit","doi":"10.4103/mjmsr.mjmsr_84_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_84_22","url":null,"abstract":"","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46079222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/mjmsr.mjmsr_74_22
G. Suganthi, Vijayakumar Praveen, Vajiravelu Suganthi, Panneerselvam Periasamy, Bagavathiammal Periyasamy, S. Gunasekaran
Background: Studies have reported that hypomagnesemia could play an essential role in the development of endothelial dysfunction and altered insulin function, particularly among type 2 diabetes mellitus (T2DM). To assess the incidence of hypomagnesemia among patients with T2DM and compare them with healthy individuals. Materials and Methods: One hundred types 2 diabetic patients admitted to the general medicine outpatient Department at Government Erode Medical College Hospital, Perundurai, were recruited. Biochemical parameters and serum magnesium were assessed at admission and compared with the 100 healthy controls without T2DM. Results: Cases and controls had mean ages of 50.39 ± 9.76 and 50.01 ± 10.15 years, respectively. The age range of 41–50 had the highest percentage of patients (42%). The gender distribution was the same for both cases and controls, with 70% of men and 30% of women. Between cases and controls, the mean fasting blood sugar levels were 102.42 ± 11.16 mg/dl and 91.93 ± 4.32 mg/dl, respectively. Conclusion: Hypomagnesemia is a common problem in adults with T2DM, and we did find a significant association between Mg levels and T2DM in Erode district, Tamil Nadu.
{"title":"Evaluation of serum magnesium levels among type 2 diabetes individuals of a South Indian town","authors":"G. Suganthi, Vijayakumar Praveen, Vajiravelu Suganthi, Panneerselvam Periasamy, Bagavathiammal Periyasamy, S. Gunasekaran","doi":"10.4103/mjmsr.mjmsr_74_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_74_22","url":null,"abstract":"Background: Studies have reported that hypomagnesemia could play an essential role in the development of endothelial dysfunction and altered insulin function, particularly among type 2 diabetes mellitus (T2DM). To assess the incidence of hypomagnesemia among patients with T2DM and compare them with healthy individuals. Materials and Methods: One hundred types 2 diabetic patients admitted to the general medicine outpatient Department at Government Erode Medical College Hospital, Perundurai, were recruited. Biochemical parameters and serum magnesium were assessed at admission and compared with the 100 healthy controls without T2DM. Results: Cases and controls had mean ages of 50.39 ± 9.76 and 50.01 ± 10.15 years, respectively. The age range of 41–50 had the highest percentage of patients (42%). The gender distribution was the same for both cases and controls, with 70% of men and 30% of women. Between cases and controls, the mean fasting blood sugar levels were 102.42 ± 11.16 mg/dl and 91.93 ± 4.32 mg/dl, respectively. Conclusion: Hypomagnesemia is a common problem in adults with T2DM, and we did find a significant association between Mg levels and T2DM in Erode district, Tamil Nadu.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41970666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_57_22
Y. Hassan, A. Rather, J. Peer
Background: Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital. Materials and Methods: This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22. Results: Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients. Conclusion: Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.
{"title":"Comparative study between aspiration followed by Intralesional triamcinolone Injection, mixture of triamcinolone and hyaluronidase and surgical excision for the treatment of forearm ganglion in a medical college hospital","authors":"Y. Hassan, A. Rather, J. Peer","doi":"10.4103/mjmsr.mjmsr_57_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_57_22","url":null,"abstract":"Background: Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital. Materials and Methods: This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22. Results: Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients. Conclusion: Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43903318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_60_22
P. Sookaromdee, V. Wiwanitkit
{"title":"Serum B12 and folate level in alcoholics and nonalcoholics: Correspondence","authors":"P. Sookaromdee, V. Wiwanitkit","doi":"10.4103/mjmsr.mjmsr_60_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_60_22","url":null,"abstract":"","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47269250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_43_22
A. Natarajan, TPreeth Pany, Nithin Theckumparampil
Introduction: COVID-19 is a major public health burden in the world, and chest computed tomography (CT) is the ideal imaging modality to diagnose and monitor disease progression. Objectives: The objective was to review the common and uncommon chest CT findings of patients with COVID-19 and to correlate the CT findings with short-term prognosis. Methods: All patients who had laboratory-confirmed COVID-19 infection and underwent CT scan were reviewed. The imaging features and the distribution of abnormality were evaluated. A CT severity score (CT-SS) system out of 40 was used. Mann–Whitney U-test and Chi-square or Fisher's exact test were used for analysis. Two-sided P < 0.05 was considered statistically significant. A receiver operating characteristic curve analysis was performed to calculate the CT-SS cutoff for hospital admission and intensive care unit (ICU) admission. Results: A total of 149 individuals were eligible. The most common imaging features were ground-glass opacities (GGO) (88%), septal thickening (70%), and reticulations (50%). The least common imaging features were pneumothorax (1%) and vascular enlargement (1%). The most common distributions of GGO were bilateral (92%) and multifocal (95%), with peripheral (100%) and lower lobe predominance (77%). A higher CT-SS had a significant association with longer hospital stay and ICU admission, with CT-SS of 18 and 10 being optimal cutoff, respectively. Conclusion: Our study is one of the few studies to correlate the imaging finding with clinical outcomes in the south Indian population. The common findings in our study were consistent with the literature. CT-SS plays an important role in predicting prognosis.
{"title":"Predicting clinical outcome with computed tomography severity score in COVID-19","authors":"A. Natarajan, TPreeth Pany, Nithin Theckumparampil","doi":"10.4103/mjmsr.mjmsr_43_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_43_22","url":null,"abstract":"Introduction: COVID-19 is a major public health burden in the world, and chest computed tomography (CT) is the ideal imaging modality to diagnose and monitor disease progression. Objectives: The objective was to review the common and uncommon chest CT findings of patients with COVID-19 and to correlate the CT findings with short-term prognosis. Methods: All patients who had laboratory-confirmed COVID-19 infection and underwent CT scan were reviewed. The imaging features and the distribution of abnormality were evaluated. A CT severity score (CT-SS) system out of 40 was used. Mann–Whitney U-test and Chi-square or Fisher's exact test were used for analysis. Two-sided P < 0.05 was considered statistically significant. A receiver operating characteristic curve analysis was performed to calculate the CT-SS cutoff for hospital admission and intensive care unit (ICU) admission. Results: A total of 149 individuals were eligible. The most common imaging features were ground-glass opacities (GGO) (88%), septal thickening (70%), and reticulations (50%). The least common imaging features were pneumothorax (1%) and vascular enlargement (1%). The most common distributions of GGO were bilateral (92%) and multifocal (95%), with peripheral (100%) and lower lobe predominance (77%). A higher CT-SS had a significant association with longer hospital stay and ICU admission, with CT-SS of 18 and 10 being optimal cutoff, respectively. Conclusion: Our study is one of the few studies to correlate the imaging finding with clinical outcomes in the south Indian population. The common findings in our study were consistent with the literature. CT-SS plays an important role in predicting prognosis.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48600511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_37_22
S. Patil, D. Patil
Pulmonary tuberculosis (TB) is the most common cause of bilateral pulmonary cavities with constitutional symptoms in India being endemic and more prevalent nature of the disease, irrespective of microscopy or nucleic acid amplification test abnormalities. Pulmonary manifestations of systemic vasculitis have very diverse involvement ranging from nodule, consolidation, and cavitation. In this case report, a 45-year-old female, presented with constitutional symptoms with lung parenchymal consolidations progressed to cavitation, and started empirical anti-TB treatment without mycobacterial microscopic or genome documentation in sputum with clinical or radiological worsening. Bronchoscopy workup is inconclusive and the tropical screen for bacterial, TB, and malignancy was negative and fungal yield Aspergillus colonization. A vasculitis workup was done in the presence of clinical and radiological worsening documented PR3-antineutrophil cytoplasmic antibody positive with very highly raised titers. We have started on steroids and cyclophosphamide with antifungals and clinical response was documented with a near-complete resolution of shadows in 24 weeks.
{"title":"Wegener's granulomatosis mimicking like pulmonary tuberculosis and presenting as cavitating lung disease with mycetoma: A case report with review of literature","authors":"S. Patil, D. Patil","doi":"10.4103/mjmsr.mjmsr_37_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_37_22","url":null,"abstract":"Pulmonary tuberculosis (TB) is the most common cause of bilateral pulmonary cavities with constitutional symptoms in India being endemic and more prevalent nature of the disease, irrespective of microscopy or nucleic acid amplification test abnormalities. Pulmonary manifestations of systemic vasculitis have very diverse involvement ranging from nodule, consolidation, and cavitation. In this case report, a 45-year-old female, presented with constitutional symptoms with lung parenchymal consolidations progressed to cavitation, and started empirical anti-TB treatment without mycobacterial microscopic or genome documentation in sputum with clinical or radiological worsening. Bronchoscopy workup is inconclusive and the tropical screen for bacterial, TB, and malignancy was negative and fungal yield Aspergillus colonization. A vasculitis workup was done in the presence of clinical and radiological worsening documented PR3-antineutrophil cytoplasmic antibody positive with very highly raised titers. We have started on steroids and cyclophosphamide with antifungals and clinical response was documented with a near-complete resolution of shadows in 24 weeks.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45191392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：