Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_65_22
Ravikanth Reddy
{"title":"Ultrasonography diagnosis of acrania–exencephaly sequence at 22 weeks gestation","authors":"Ravikanth Reddy","doi":"10.4103/mjmsr.mjmsr_65_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_65_22","url":null,"abstract":"","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43534772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_34_22
P. Das, Soma Ghosh, U. Banerjee
Background: Chronic renal failure (CRF), a debilitating condition responsible for high morbidity and mortality considered a financial burden to the government and society. Determining the prevalence of CRF in any country is important for planning the care of affected patients. Aim and Objectives: The study aimed at looking for the hematological changes before, and following hemodialysis (HD) in CRF patients. The objectives included comparing complete hemogram, coagulation profile, and blood biochemistry before and after HD; determining hematological complications post-HD; taking precautions to reduce morbidity and mortality from hematological point of view; and assessing changes in hematological profile of CRF patients undergoing HD. Materials and Methods: An institutional cross-sectional study was done on 62 patients of CRF undergoing HD. The hematological and biochemical parameters were studied along with urinary findings. Results: Males were more affected in the study. The hematological parameters which were elevated following dialysis were total leukocyte count, erythrocyte sedimentation rate, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin (MCH), bleeding and clotting time, prothrombin time, activated partial thromboplastin time, but MCH concentration and platelet count showed a fall. Postprandial blood sugar, calcium and erythropoietin showed elevated levels following hemodialysis., while decreased levels were found in fasting blood sugar, sodium, potassium, phosphate, urea, and creatinine. Urinary studies showed a increase in specific gravity and a decrease in 24 h urinary protein. Conclusion: CRF is becoming a dreadful condition in society, with dialysis playing an eminent role in treatment modality. Formulating precautions before and after dialysis based on various hematological and biochemical parameters can help to reduce morbidity and mortality.
{"title":"Study of hematological changes in patients with chronic renal failure undergoing hemodialysis (pre and post)","authors":"P. Das, Soma Ghosh, U. Banerjee","doi":"10.4103/mjmsr.mjmsr_34_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_34_22","url":null,"abstract":"Background: Chronic renal failure (CRF), a debilitating condition responsible for high morbidity and mortality considered a financial burden to the government and society. Determining the prevalence of CRF in any country is important for planning the care of affected patients. Aim and Objectives: The study aimed at looking for the hematological changes before, and following hemodialysis (HD) in CRF patients. The objectives included comparing complete hemogram, coagulation profile, and blood biochemistry before and after HD; determining hematological complications post-HD; taking precautions to reduce morbidity and mortality from hematological point of view; and assessing changes in hematological profile of CRF patients undergoing HD. Materials and Methods: An institutional cross-sectional study was done on 62 patients of CRF undergoing HD. The hematological and biochemical parameters were studied along with urinary findings. Results: Males were more affected in the study. The hematological parameters which were elevated following dialysis were total leukocyte count, erythrocyte sedimentation rate, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin (MCH), bleeding and clotting time, prothrombin time, activated partial thromboplastin time, but MCH concentration and platelet count showed a fall. Postprandial blood sugar, calcium and erythropoietin showed elevated levels following hemodialysis., while decreased levels were found in fasting blood sugar, sodium, potassium, phosphate, urea, and creatinine. Urinary studies showed a increase in specific gravity and a decrease in 24 h urinary protein. Conclusion: CRF is becoming a dreadful condition in society, with dialysis playing an eminent role in treatment modality. Formulating precautions before and after dialysis based on various hematological and biochemical parameters can help to reduce morbidity and mortality.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48982942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_53_22
P. Chakraborty, Priti Majumder, R. Mondal, P. Halder
Poland syndrome (PS) is a rare congenital disorder characterized by ipsilateral syndactyly and unilateral hypoaplasia of the chest wall. It may also be accompanied by dextrocardia, vertebral deformities, and renal malformations such as undescended testes and pyelonephritis. The degree of intrathoracic visceral compression and chest wall involvement dictate the course of treatment. Surgical drainage is occasionally required to treat sepsis and chronic infection. We present the case of an 11-month-old infant who had bilateral PS, horseshoe kidneys, and right-sided hydronephrosis, which is quite a rare association as per existing literature.
{"title":"Bilateral Poland anomalies with horseshoe kidney: A rare association","authors":"P. Chakraborty, Priti Majumder, R. Mondal, P. Halder","doi":"10.4103/mjmsr.mjmsr_53_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_53_22","url":null,"abstract":"Poland syndrome (PS) is a rare congenital disorder characterized by ipsilateral syndactyly and unilateral hypoaplasia of the chest wall. It may also be accompanied by dextrocardia, vertebral deformities, and renal malformations such as undescended testes and pyelonephritis. The degree of intrathoracic visceral compression and chest wall involvement dictate the course of treatment. Surgical drainage is occasionally required to treat sepsis and chronic infection. We present the case of an 11-month-old infant who had bilateral PS, horseshoe kidneys, and right-sided hydronephrosis, which is quite a rare association as per existing literature.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46533018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_54_22
M. Al-Mendalawi
{"title":"Normative value of sensory nerve action potential of median and ulnar nerves: A cross-sectional study among healthy adults","authors":"M. Al-Mendalawi","doi":"10.4103/mjmsr.mjmsr_54_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_54_22","url":null,"abstract":"","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46579473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_56_22
Archita Chandra, S. Mallik, S. Chakrabarti, N. Bhattacharyya
Context: Chronic diseases such as beta-thalassemia major among children impact their parents in various ways, as they face continuous stress and strain while striving to provide their children with a best possible care. Literature related to health-related quality of life (HRQoL) among parents of children with beta-thalassemia major are limited among Indian population. Aims: This study aimed to assess the HRQoL of parents of children with beta-thalassemia major attending a tertiary care institution in Eastern India and its various correlates. Settings and Design: This cross-sectional study was conducted at a tertiary care institution in Eastern India. Materials and Methods: A sample size of 192 was selected using the simple random sampling among parents with children suffering from beta-thalassemia major who fulfilled the inclusion criteria. Study participants were interviewed regarding different variables and their HRQoL, using a predesigned, pretested, and semi-structured schedule and the Short Form 36 Health survey, respectively, after obtaining ethical clearance from the Institutional Ethics Committee and informed consent from them. Statistical Analysis Used: Data were entered in MS Excel and analyzed using IBM SPSS 20.0 version (Armonk, NY: IBM Corp). Results: The mean HRQoL score was found to be 38.7 ± 11.3 with an interquartile range of 23–59.7. The Spearman's rho correlation matrix showed that HRQol of parents is weakly positively correlated with the educational status of the father of the child (r = 0.2), educational status of the mother of the child (r = 0.1), family history of thalassemia (r = 0.2), ongoing treatment (r = 0.1), and duration of blood transfusion (r = 0.2). Conclusions: Hence, we can conclude that HRQoL of parents of beta-thalassemia major children was correlated with the educational status of the father and mother, family history of thalassemia, ongoing treatment, and duration of blood transfusion.
{"title":"Health-related quality of life of parents of children with beta-thalassemia major attending a tertiary care institution in Eastern India","authors":"Archita Chandra, S. Mallik, S. Chakrabarti, N. Bhattacharyya","doi":"10.4103/mjmsr.mjmsr_56_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_56_22","url":null,"abstract":"Context: Chronic diseases such as beta-thalassemia major among children impact their parents in various ways, as they face continuous stress and strain while striving to provide their children with a best possible care. Literature related to health-related quality of life (HRQoL) among parents of children with beta-thalassemia major are limited among Indian population. Aims: This study aimed to assess the HRQoL of parents of children with beta-thalassemia major attending a tertiary care institution in Eastern India and its various correlates. Settings and Design: This cross-sectional study was conducted at a tertiary care institution in Eastern India. Materials and Methods: A sample size of 192 was selected using the simple random sampling among parents with children suffering from beta-thalassemia major who fulfilled the inclusion criteria. Study participants were interviewed regarding different variables and their HRQoL, using a predesigned, pretested, and semi-structured schedule and the Short Form 36 Health survey, respectively, after obtaining ethical clearance from the Institutional Ethics Committee and informed consent from them. Statistical Analysis Used: Data were entered in MS Excel and analyzed using IBM SPSS 20.0 version (Armonk, NY: IBM Corp). Results: The mean HRQoL score was found to be 38.7 ± 11.3 with an interquartile range of 23–59.7. The Spearman's rho correlation matrix showed that HRQol of parents is weakly positively correlated with the educational status of the father of the child (r = 0.2), educational status of the mother of the child (r = 0.1), family history of thalassemia (r = 0.2), ongoing treatment (r = 0.1), and duration of blood transfusion (r = 0.2). Conclusions: Hence, we can conclude that HRQoL of parents of beta-thalassemia major children was correlated with the educational status of the father and mother, family history of thalassemia, ongoing treatment, and duration of blood transfusion.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44267630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_42_22
B. Narasimha, R. Kamath, Sharvanan Udayar, Ashwini Madeshan
Introduction: Floods are the most commonly occurring hydrological disasters in India. The disaster wastes (DWs) produced in floods involve various departments to clear the waste and consume more resources. Thus, the study was conducted to assess the type and visual quantity of DW during the initial recovery phase in flood-affected areas of the Kodagu district. Materials and Methods: A qualitative study was conducted in randomly selected 10 flood-affected areas in September 2019. Data were collected by a structured questionnaire and analyzed using Epi Info version 7.2. Results: The DWs were present in all 10 areas and it was classified into seven types. Out of 10 flood-affected areas, the majority of the areas had packaging wastes (nine areas) and bedding/furniture/cloth/textile waste (nine areas), followed by rubble/building material (six areas), electrical/electronic waste (five areas), food waste (three areas), and toxic/harmful/hazardous waste and biomedical waste/hospital waste (two areas). The total DW visual quantity was 6220 kg and was highest for rubble/building material DW. Conclusions: The DWs were containing both biomedical and nonbiomedical wastes. The wastes clogged the canals and polluted mainly water and soil. The visual quantity of DW was more and clearing the waste was difficult without the vehicles.
简介：洪水是印度最常见的水文灾害。洪水中产生的灾害废物涉及各个部门，以清理废物并消耗更多的资源。因此，本研究旨在评估Kodagu区受洪水影响地区初始恢复阶段DW的类型和视觉量。材料和方法：2019年9月，随机选择10个受洪水影响的地区进行定性研究。通过结构化问卷收集数据，并使用Epi Info 7.2版进行分析。结果：DWs分布于10个区域，分为7种类型。在10个受洪水影响的地区中，大多数地区有包装垃圾（9个地区）和床上用品/家具/布/纺织垃圾（9区），其次是瓦砾/建筑材料（6区）、电气/电子垃圾（5区）、食物垃圾（3区），以及有毒/有害/危险废物和生物医学废物/医院废物（2区）。DW视觉总量为6220kg，碎石/建筑材料的DW最高。结论：DWs同时含有生物医学废物和非生物医学废物。废物堵塞了运河，主要污染了水和土壤。DW的视觉数量更多，如果没有车辆，很难清除废物。
{"title":"Field test and reporting of disaster waste mapping in flood-affected areas of Kodagu district","authors":"B. Narasimha, R. Kamath, Sharvanan Udayar, Ashwini Madeshan","doi":"10.4103/mjmsr.mjmsr_42_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_42_22","url":null,"abstract":"Introduction: Floods are the most commonly occurring hydrological disasters in India. The disaster wastes (DWs) produced in floods involve various departments to clear the waste and consume more resources. Thus, the study was conducted to assess the type and visual quantity of DW during the initial recovery phase in flood-affected areas of the Kodagu district. Materials and Methods: A qualitative study was conducted in randomly selected 10 flood-affected areas in September 2019. Data were collected by a structured questionnaire and analyzed using Epi Info version 7.2. Results: The DWs were present in all 10 areas and it was classified into seven types. Out of 10 flood-affected areas, the majority of the areas had packaging wastes (nine areas) and bedding/furniture/cloth/textile waste (nine areas), followed by rubble/building material (six areas), electrical/electronic waste (five areas), food waste (three areas), and toxic/harmful/hazardous waste and biomedical waste/hospital waste (two areas). The total DW visual quantity was 6220 kg and was highest for rubble/building material DW. Conclusions: The DWs were containing both biomedical and nonbiomedical wastes. The wastes clogged the canals and polluted mainly water and soil. The visual quantity of DW was more and clearing the waste was difficult without the vehicles.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41346927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_38_22
Joel Sabu, K. Nayak, Joshua Chacko, A. Karintholil
Background: Health-care professionals managing the pandemic are at higher risk of developing psychological distress and posttraumatic stress symptoms. The study highlights the importance of evaluating mental health among health-care workers to improve efficiency at work and also proves to be a major step to prevent suicide among health-care workers. Materials and Methods: The authors conducted a cross-sectional questionnaire-based clinical study, using the Depression, Anxiety, and Stress Scale-21 to assess stress, anxiety, and depressive symptoms among doctors and nurses managing COVID-19 patients in Karnataka. Results: Of 233 participants, 3 (1.3%), 27 (11.6%), 15 (6.4%), and 159 (68.2%) participants were suffering from mild, moderate, severe, and extremely severe anxiety respectively; 17 (7.3%), 32 (13.7%), 21 (9%), and 131 (56.2%) are suffering from mild, moderate, severe, extremely severe depressive symptoms, respectively; 15 (6.4%), 19 (8.2%), 26 (11.2%), and 114 (48.9%) are suffering from mild, moderate, severe, and extremely severe stress, respectively. The study also showed that health-care workers who had faced an epidemic in the past were able to cope up with the change in a scenario as compared to those who had not in the past. Conclusion: The study shows the prevalence of stress, anxiety, and depressive symptoms in doctors and nurses. It also shows that people who had exposure to a pandemic in the past were able to cope up better with the situation.
{"title":"Anxiety and depressive symptoms in health-care workers managing COVID-19 patients: A cross-sectional study","authors":"Joel Sabu, K. Nayak, Joshua Chacko, A. Karintholil","doi":"10.4103/mjmsr.mjmsr_38_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_38_22","url":null,"abstract":"Background: Health-care professionals managing the pandemic are at higher risk of developing psychological distress and posttraumatic stress symptoms. The study highlights the importance of evaluating mental health among health-care workers to improve efficiency at work and also proves to be a major step to prevent suicide among health-care workers. Materials and Methods: The authors conducted a cross-sectional questionnaire-based clinical study, using the Depression, Anxiety, and Stress Scale-21 to assess stress, anxiety, and depressive symptoms among doctors and nurses managing COVID-19 patients in Karnataka. Results: Of 233 participants, 3 (1.3%), 27 (11.6%), 15 (6.4%), and 159 (68.2%) participants were suffering from mild, moderate, severe, and extremely severe anxiety respectively; 17 (7.3%), 32 (13.7%), 21 (9%), and 131 (56.2%) are suffering from mild, moderate, severe, extremely severe depressive symptoms, respectively; 15 (6.4%), 19 (8.2%), 26 (11.2%), and 114 (48.9%) are suffering from mild, moderate, severe, and extremely severe stress, respectively. The study also showed that health-care workers who had faced an epidemic in the past were able to cope up with the change in a scenario as compared to those who had not in the past. Conclusion: The study shows the prevalence of stress, anxiety, and depressive symptoms in doctors and nurses. It also shows that people who had exposure to a pandemic in the past were able to cope up better with the situation.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48648888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_41_22
Paramita Sarkar, Arnab Sarkar, Rivu Basu
Context: Cancer is a serious global public health problem. Public awareness plays a big role in the prevention of cancer. Aims: This study aims to evaluate influence of sociodemographic characteristics and related factors on knowledge, attitude, and practice (KAP) regarding the prevention of common cancers. Settings and Design: This community-based observational, cross-sectional study was conducted in the slum area of urban field practice area of a tertiary care hospital, Kolkata. Materials and Methods: The survey was conducted with a sample of 415 using a semistructured questionnaire related to KAP regarding the prevention of cancers. Mann–Whitney U-test and Kruskal–Wallis test were conducted to determine group differences for sociodemographic variables. Linear correlational analysis was performed to identify associated factors and measure the strength and direction of relationships Results: Median scores for knowledge, attitude, and practice differed by sociodemographic characteristics. Positive correlations were observed between knowledge–attitude (r = 0.395, P < 0.01), attitude–practice (r = 0.391, P < 0.01), and knowledge–practice (r = 0.460, P < 0.01). Age, gender, educational status, and socioeconomic class were significantly associated with KAP score of participants. Conclusions: Knowledge about primary preventive measure was found to be less. The study found varying degrees of positive correlation between KAP. Knowledge and level of education had positive associations with attitude and adherence to preventive measures. The findings suggest a need for targeted community awareness interventions for the elderly populations, among men and those with no school education. The positive linear correlations reaffirm that better knowledge can lead to positive attitude and subsequently in good practices. Extensive health educational campaigns should be provided to the general population.
{"title":"Sociodemographic factors influencing knowledge, attitude, and practices regarding the prevention of common cancers among adults in urban slum, Kolkata","authors":"Paramita Sarkar, Arnab Sarkar, Rivu Basu","doi":"10.4103/mjmsr.mjmsr_41_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_41_22","url":null,"abstract":"Context: Cancer is a serious global public health problem. Public awareness plays a big role in the prevention of cancer. Aims: This study aims to evaluate influence of sociodemographic characteristics and related factors on knowledge, attitude, and practice (KAP) regarding the prevention of common cancers. Settings and Design: This community-based observational, cross-sectional study was conducted in the slum area of urban field practice area of a tertiary care hospital, Kolkata. Materials and Methods: The survey was conducted with a sample of 415 using a semistructured questionnaire related to KAP regarding the prevention of cancers. Mann–Whitney U-test and Kruskal–Wallis test were conducted to determine group differences for sociodemographic variables. Linear correlational analysis was performed to identify associated factors and measure the strength and direction of relationships Results: Median scores for knowledge, attitude, and practice differed by sociodemographic characteristics. Positive correlations were observed between knowledge–attitude (r = 0.395, P < 0.01), attitude–practice (r = 0.391, P < 0.01), and knowledge–practice (r = 0.460, P < 0.01). Age, gender, educational status, and socioeconomic class were significantly associated with KAP score of participants. Conclusions: Knowledge about primary preventive measure was found to be less. The study found varying degrees of positive correlation between KAP. Knowledge and level of education had positive associations with attitude and adherence to preventive measures. The findings suggest a need for targeted community awareness interventions for the elderly populations, among men and those with no school education. The positive linear correlations reaffirm that better knowledge can lead to positive attitude and subsequently in good practices. Extensive health educational campaigns should be provided to the general population.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49557766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_49_22
P. Deepthi, Sandhya George, Anita Sanker, N. Asokan
Background: Adverse cutaneous drug reactions (ACDRs) present with different morphologies and times of onset. Knowledge about the common drugs causing them, their reaction time (time interval between drug intake and the onset of symptoms), and the clinical presentations are helpful in identifying an offending drug, especially in the setting of multiple drug therapies, thereby reducing the morbidity and mortality associated with them. Aims: This study aims to identify causative drugs and clinical patterns of ACDRs in a tertiary care center and to estimate their reaction time. Methods: Sixty-two patients diagnosed to have ACDRs who attended the department of dermatology of a tertiary care teaching hospital during an 18-month period were selected for the study. They were classified into certain, probable, or possible categories as per the World Health Organization-Uppsala Monitoring Centre (WHO-UMC) classification. The frequency of each type of drug reaction, common causative agents, and reaction time of different drug reactions was analyzed. Results: Of the 62 patients, 40 (64.5%) were probable, 18 (29%) possible, and 4 (6.4%) were certain. The most common types of reactions encountered were fixed drug eruption (FDE) (13, 21%), drug hypersensitivity syndrome (12, 19.4%), and maculopapular rash (9, 14.5%). As a single group of drugs, antimicrobials were the most common causative agents (23, 37%) followed by anticonvulsants (16, 25.8%). As an individual drug, phenytoin was the most common causative agent (10, 16.1%), followed by paracetamol (7, 11.3%) and isoniazid (5, 8.1%). Reaction time varied from less than an hour for FDE and urticaria to 3–4 months for exfoliative dermatitis, lichenoid eruption, and folliculitis. Limitations: Small sample size was the major limitation. Conclusion: Reaction time varied from less than 24 h in FDE, urticaria, and angioedema to 3–4 months in exfoliative dermatitis, lichenoid eruption, and folliculitis.
{"title":"A cross-sectional study of adverse cutaneous drug reactions with special reference to reaction time","authors":"P. Deepthi, Sandhya George, Anita Sanker, N. Asokan","doi":"10.4103/mjmsr.mjmsr_49_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_49_22","url":null,"abstract":"Background: Adverse cutaneous drug reactions (ACDRs) present with different morphologies and times of onset. Knowledge about the common drugs causing them, their reaction time (time interval between drug intake and the onset of symptoms), and the clinical presentations are helpful in identifying an offending drug, especially in the setting of multiple drug therapies, thereby reducing the morbidity and mortality associated with them. Aims: This study aims to identify causative drugs and clinical patterns of ACDRs in a tertiary care center and to estimate their reaction time. Methods: Sixty-two patients diagnosed to have ACDRs who attended the department of dermatology of a tertiary care teaching hospital during an 18-month period were selected for the study. They were classified into certain, probable, or possible categories as per the World Health Organization-Uppsala Monitoring Centre (WHO-UMC) classification. The frequency of each type of drug reaction, common causative agents, and reaction time of different drug reactions was analyzed. Results: Of the 62 patients, 40 (64.5%) were probable, 18 (29%) possible, and 4 (6.4%) were certain. The most common types of reactions encountered were fixed drug eruption (FDE) (13, 21%), drug hypersensitivity syndrome (12, 19.4%), and maculopapular rash (9, 14.5%). As a single group of drugs, antimicrobials were the most common causative agents (23, 37%) followed by anticonvulsants (16, 25.8%). As an individual drug, phenytoin was the most common causative agent (10, 16.1%), followed by paracetamol (7, 11.3%) and isoniazid (5, 8.1%). Reaction time varied from less than an hour for FDE and urticaria to 3–4 months for exfoliative dermatitis, lichenoid eruption, and folliculitis. Limitations: Small sample size was the major limitation. Conclusion: Reaction time varied from less than 24 h in FDE, urticaria, and angioedema to 3–4 months in exfoliative dermatitis, lichenoid eruption, and folliculitis.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45592123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.4103/mjmsr.mjmsr_51_22
R. Mungmunpuntipantip, V. Wiwanitkit
{"title":"COVID-19, casino, brothel, illegal activity, and disease control","authors":"R. Mungmunpuntipantip, V. Wiwanitkit","doi":"10.4103/mjmsr.mjmsr_51_22","DOIUrl":"https://doi.org/10.4103/mjmsr.mjmsr_51_22","url":null,"abstract":"","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70833813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：