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Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology最新文献

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[Malignant lymphoma of the skin--especially cutaneous T-cell lymphoma]. [皮肤恶性淋巴瘤——尤其是皮肤t细胞淋巴瘤]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
H Nakajima
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引用次数: 0
[Six cases of Sjögren's syndrome with lichen mucosae--studies on the histopathology of salivary gland and clinical manifestation of sicca features in the patients with lichen mucosae]. 【Sjögren综合征伴粘膜地衣6例——粘膜地衣患者涎腺组织病理学及干枯特征临床表现的研究】。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
R Tanei, I Katayama, I Katou, Y Ota, S Nishiyama

A case of a 54-year old man with lichen mucosae and Sjögren's syndrome was reported. Clinical and histopathological analysis was made on the presence of sicca features in 6 patients with lichen mucosae. All patients complained either xerophthalmia or xerostomia and 5 out of 6 cases showed specific lymphocytic foci seen in Sjögren's syndrome in addition to lichenoid tissue reaction in the specimen obtained from buccal mucosae. Objective keratoconjunctivitis sicca was demonstrated in 3 cases. Immunologically, abnormal laboratory findings were observed in 5 cases (4 cases with a positive ANA and 3 cases with a positive anti microsome antibody). These findings suggest that lichen mucosae might develop in a close association with Sjögren's syndrome and relationship between these two disease was discussed in this article.

本文报告一例54岁男性伴有粘膜苔藓和Sjögren综合征。对6例粘膜苔藓病变的临床及组织病理学特征进行分析。所有患者均表现为干眼症或口干症，6例患者中有5例出现Sjögren综合征特有的淋巴细胞灶，并在口腔黏膜标本中发现苔藓样组织反应。目的观察3例干枯性角膜结膜炎的临床表现。免疫学方面，实验室检查异常5例，其中抗微粒体抗体阳性4例，抗微粒体抗体阳性3例。这些结果提示，粘膜苔藓的发生可能与Sjögren综合征密切相关，本文讨论了两者之间的关系。
{"title":"[Six cases of Sjögren's syndrome with lichen mucosae--studies on the histopathology of salivary gland and clinical manifestation of sicca features in the patients with lichen mucosae].","authors":"R Tanei,&nbsp;I Katayama,&nbsp;I Katou,&nbsp;Y Ota,&nbsp;S Nishiyama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of a 54-year old man with lichen mucosae and Sjögren's syndrome was reported. Clinical and histopathological analysis was made on the presence of sicca features in 6 patients with lichen mucosae. All patients complained either xerophthalmia or xerostomia and 5 out of 6 cases showed specific lymphocytic foci seen in Sjögren's syndrome in addition to lichenoid tissue reaction in the specimen obtained from buccal mucosae. Objective keratoconjunctivitis sicca was demonstrated in 3 cases. Immunologically, abnormal laboratory findings were observed in 5 cases (4 cases with a positive ANA and 3 cases with a positive anti microsome antibody). These findings suggest that lichen mucosae might develop in a close association with Sjögren's syndrome and relationship between these two disease was discussed in this article.</p>","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 12","pages":"1241-9"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13233131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Skin surface pH of hemodialysis patients]. [血液透析患者皮肤表面pH值]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
K Ishida, T Kamiya, S Tsuchiya, A Hattori

The skin surface pH of 88 patients undergoing hemodialysis was investigated. The average of skin surface pH as measured at four different sites (forehead, forearm, palm and lower leg) was 4.5-5.0 and 5.0-6.0 in normal subjects and patients respectively. The difference in the two results was regarded as significant by Student's t test (p less than 0.01).

研究了88例血液透析患者皮肤表面pH值。正常人和患者四个不同部位(额头、前臂、手掌和小腿)皮肤表面pH值平均值分别为4.5 ~ 5.0和5.0 ~ 6.0。经Student's t检验，认为两项结果差异有统计学意义(p < 0.01)。
{"title":"[Skin surface pH of hemodialysis patients].","authors":"K Ishida,&nbsp;T Kamiya,&nbsp;S Tsuchiya,&nbsp;A Hattori","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The skin surface pH of 88 patients undergoing hemodialysis was investigated. The average of skin surface pH as measured at four different sites (forehead, forearm, palm and lower leg) was 4.5-5.0 and 5.0-6.0 in normal subjects and patients respectively. The difference in the two results was regarded as significant by Student's t test (p less than 0.01).</p>","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 12","pages":"1275-8"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13233136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[HLA antigens in 11 cases of patients with recurrent erythema and anti-SS-B antibody]. 【11例复发性红斑患者HLA抗原及抗ss - b抗体】。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
H Niizeki, Y Amano, T Hashimoto, T Nishikawa, A Sonoda

HLA antigens were studied in 11 cases of patients with recurrent erythema and anti-SS-B antibody. Among DR antigens positive associations with DR5, DRw6 (including DRw13), and DRw52 were obtained. These data demonstrated that 11 cases of this report are immunogenetically closely related to each other and appear to be related to Sjögren's/lupus erythematosus overlap patients.

对11例复发性红斑患者的HLA抗原及抗ss - b抗体进行了检测。在DR抗原中，与DR5、DRw6(包括DRw13)、DRw52呈正相关。这些数据表明，本报告的11例彼此免疫遗传学密切相关，似乎与Sjögren /红斑狼疮重叠患者有关。
{"title":"[HLA antigens in 11 cases of patients with recurrent erythema and anti-SS-B antibody].","authors":"H Niizeki,&nbsp;Y Amano,&nbsp;T Hashimoto,&nbsp;T Nishikawa,&nbsp;A Sonoda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>HLA antigens were studied in 11 cases of patients with recurrent erythema and anti-SS-B antibody. Among DR antigens positive associations with DR5, DRw6 (including DRw13), and DRw52 were obtained. These data demonstrated that 11 cases of this report are immunogenetically closely related to each other and appear to be related to Sjögren's/lupus erythematosus overlap patients.</p>","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 12","pages":"1271-4"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13233135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Aging of the skin]. [皮肤老化]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
T Tsuji
{"title":"[Aging of the skin].","authors":"T Tsuji","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 13","pages":"1345-7"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Drug eruption in old age]. [老年药疹]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
S Shiraishi, Y Shirakata
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引用次数: 0
[Expression pattern of retinoic acid receptor genes in normal human skin]. 维甲酸受体基因在正常人皮肤中的表达模式
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
W Fujimoto

Expression pattern of the retinoic acid receptor (RAR) genes in normal human skin was investigated by in situ hybridization method. Using the riboprobes from cDNAs for three subtypes of RAR, we found that the RAR-alpha and the RAR-gamma genes were expressed in the epidermis. Significant expression of the RAR-beta gene was detected neither in the epidermis nor in the dermis. Expression of the RAR-alpha and -gamma genes was detected both in te basal cell layer and in the squamous cell layers. Moreover, the RAR-alpha and -gamma genes were expressed in the eccrine sweat glands as well. These results indicate that the target cells for retinoic acid (RA) in human skin are keratinocytes and the epithelial cells of epidermal appendages. These findings thus demonstrate that, among three subtypes of RAR, both RAR-alpha and RAR-gamma are essential for control of epidermal and epithelial cell differentiation in human skin.

采用原位杂交方法研究了维甲酸受体(RAR)基因在正常人皮肤中的表达规律。利用RAR三种亚型cdna的核糖探针，我们发现RAR- α和RAR- γ基因在表皮中表达。在表皮和真皮中均未检测到rar - β基因的显著表达。rar - α和- γ基因在基底细胞层和鳞状细胞层均有表达。此外，rar - α和- γ基因也在分泌汗腺中表达。这些结果表明，维甲酸(RA)在人皮肤中的靶细胞是角质形成细胞和表皮附属物的上皮细胞。因此，这些发现表明，在RAR的三种亚型中，RAR- α和RAR- γ都是控制人类皮肤表皮和上皮细胞分化所必需的。
{"title":"[Expression pattern of retinoic acid receptor genes in normal human skin].","authors":"W Fujimoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Expression pattern of the retinoic acid receptor (RAR) genes in normal human skin was investigated by in situ hybridization method. Using the riboprobes from cDNAs for three subtypes of RAR, we found that the RAR-alpha and the RAR-gamma genes were expressed in the epidermis. Significant expression of the RAR-beta gene was detected neither in the epidermis nor in the dermis. Expression of the RAR-alpha and -gamma genes was detected both in te basal cell layer and in the squamous cell layers. Moreover, the RAR-alpha and -gamma genes were expressed in the eccrine sweat glands as well. These results indicate that the target cells for retinoic acid (RA) in human skin are keratinocytes and the epithelial cells of epidermal appendages. These findings thus demonstrate that, among three subtypes of RAR, both RAR-alpha and RAR-gamma are essential for control of epidermal and epithelial cell differentiation in human skin.</p>","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 12","pages":"1227-33"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13121548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Topical psoralen photochemotherapy (PUVA therapy) for severe atopic dermatitis (I): An analysis of correlation between effectiveness of PUVA therapy and clinical parameters]. 局部补骨脂素光化学治疗严重特应性皮炎(I): PUVA治疗效果与临床参数的相关性分析
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
S Minaguchi, T Yoshiike, Y Aikawa, S Nakajima, J Sindhvananda, H Ogawa

Twenty-five patients with severe atopic dermatitis (AD) were subjected to PUVA therapy (topical 8-MOP application plus UVA irradiation). Excellent resolution was achieved in 18 cases (72%). Complete remission lasting 6.3 months in average was gained. In addition, the correlation between effectiveness of PUVA therapy and clinical parameters was statistically analyzed. As a result, an effectiveness of PUVA on AD was well correlated with sex (female), lower minimal phototoxic dose, higher severity and higher blood eosinophil counts. On the other hand, such correlation with the effectiveness was little in serum IgE levels, IgE.RAST scores to the house dust antigens and total irradiation doses.

对25例重度特应性皮炎(AD)患者进行了PUVA治疗(局部8-MOP涂抹加UVA照射)。18例(72%)获得了良好的分辨率。完全缓解平均持续6.3个月。并对PUVA治疗效果与临床参数的相关性进行统计学分析。因此，PUVA治疗AD的有效性与性别(女性)、最小光毒性剂量较低、严重程度较高和血液嗜酸性粒细胞计数较高相关。另一方面，血清IgE水平与疗效的相关性较小。RAST对屋尘抗原和总辐照剂量的评分。
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引用次数: 0
[Functional anatomy on the hypothalamic-hypophysial-adrenocortical axis]. [下丘脑-垂体-肾上腺皮质轴的功能解剖]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
S Daikoku
{"title":"[Functional anatomy on the hypothalamic-hypophysial-adrenocortical axis].","authors":"S Daikoku","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 13","pages":"1312-5"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Light and skin]. [光和皮肤]。
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology
Pub Date : 1990-11-01
H Takebe
{"title":"[Light and skin].","authors":"H Takebe","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":"100 13","pages":"1326-7"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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