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Hospital activities and CoViD-19: the case study of a Urology Department 医院活动与CoViD-19:以泌尿外科为例
I. Loperto, A. Borrelli, Michele Sparano, M. Triassi
The CoViD-19 pandemic is an international public health emergency. The management of the hospitals found themselves facing an ever-increasing demand for beds, especially for intensive care, thus having to make critical decisions in a short time. A shared action was to block elective surgery deemed deferrable and to transfer resources to the management of the pandemic. The activity of the surgical departments has therefore undergone substantial alterations. In this study, logistic regression and statistical analysis was used to characterize this difference for the Urology Department in "San Giovanni di Dio and Ruggi d'Aragona" University Hospital of Salerno (Italy) by analyzing a set of variables and compared the data obtained in the year 2019, pre-pandemic, with that recorded the following year, in the height of the pandemic. The results show an increased number of emergency hospitalizations as well as scheduled hospitalizations with pre-admission.
新冠肺炎大流行是一场国际突发公共卫生事件。医院的管理人员发现自己面临着日益增长的床位需求,特别是对重症监护的床位需求,因此必须在短时间内做出关键决定。一项共同行动是阻止被认为可推迟的择期手术,并将资源转移到大流行病的管理上。因此,外科部门的活动发生了实质性的变化。在这项研究中,通过分析一组变量,并将2019年大流行前获得的数据与次年大流行高峰期记录的数据进行比较,采用逻辑回归和统计分析来表征萨勒诺“圣乔瓦尼·迪迪奥和鲁吉·阿拉戈纳”大学医院泌尿科的这一差异。结果显示急诊住院人数和住院前计划住院人数均有所增加。
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引用次数: 0
The evolution of skin tissue engineering: A review on recent trends and advances 皮肤组织工程的演变:最近的趋势和进展综述
Haohong Wu
Skin plays an indispensable role in protection, sensation, temperature regulation and so on. Autologous skin grafting is the main method to treat skin wounds. However, patients with large-scale skin defects often face the problem of insufficient autologous skin, and the emergence of tissue engineering effectively compensates for the lack of skin sources. In recent years, with the efforts of scientists, skin tissue engineering technology has made some progress. In this paper, the development of skin tissue engineering in scaffold materials, seed cells and growth factors are reviewed, hoping to provide reference for the progress of skin tissue engineering.
皮肤在保护、感觉、温度调节等方面起着不可或缺的作用。自体皮肤移植是治疗皮肤创面的主要方法。然而,大面积皮肤缺损患者往往面临自体皮肤不足的问题,组织工程的出现有效地弥补了皮肤来源的不足。近年来,在科学家的努力下,皮肤组织工程技术取得了一定的进展。本文就皮肤组织工程在支架材料、种子细胞和生长因子等方面的研究进展进行综述,希望能为皮肤组织工程的发展提供参考。
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引用次数: 0
Analysis of voluntary departures from the Emergency Department of the hospital AORN “A. Cardarelli” 医院急诊科自愿离职分析。Cardarelli”
A. M. Ponsiglione, Massimo Majolo, G. Longo, Giuseppe Russo, M. Triassi, E. Raiola, G. Improta
The emergency department (ED) is the access point for urgent cases within the health facility. In recent years, however, several factors have led to a massive use of ED as a privileged access method to assistance even for patients who do not need timely treatment. This flow of so-called "non-urgent" cases generates pressure on the ED resources, leading to a considerable increase in waiting times which, in turn, generates an increase in patients who leave the ED before being visited from medical doctors. In this work, we investigate some of the factors that may lead to the decision to leave the ED before the first visit. Data were collected at the hospital A.O.R.N. “A. Cardarelli” of Naples (Italy) and then analyzed through traditional statistical tools and more advanced machine learning algorithms.
急诊部(ED)是卫生设施内紧急病例的接入点。然而,近年来,一些因素导致ED作为一种特权获取方法的大量使用,甚至对不需要及时治疗的患者也是如此。这种所谓的"非紧急"病例的流动对急诊科的资源造成压力,导致等待时间大大增加,这反过来又导致在医生探视之前离开急诊科的病人增加。在这项工作中,我们调查了一些可能导致在第一次就诊前决定离开急诊室的因素。数据是在医院的A.O.R.N. A收集的。然后通过传统的统计工具和更先进的机器学习算法进行分析。
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引用次数: 2
Investigation of factors increasing waiting times in the Emergency Departments of “San Giovanni di Dio e Ruggi d'Aragona” Hospital through machine learning 通过机器学习对“圣乔瓦尼迪迪奥鲁吉达阿拉戈纳”医院急诊科等待时间增加的因素进行调查
Cristiana Giglio, C. Lauri, Antonio Della Vecchia, A. Borrelli, Giuseppe Russo, M. Triassi, G. Improta
Emergency Departments (EDs) overcrowding is an acknowledged critical issue affecting international public health in recent years, that arises from both the growth of the health care supply/demand imbalance and the lack of beds available in hospitals wards and EDs. Emergency department length of stay (ED-LOS) is identified as a valuable key measure of EDs bottlenecks, and specifically of the rapidity of access to care for patients and of the overcrowding. ED-LOS measures how long patients stay in the ED from their first registration and triage to their admittance to a hospital ward or their discharge. Prolonged ED-LOS has been associated with adverse outcomes, such as reduced level of quality of care and patient satisfaction, increased risk of mortality and financial loss. Understanding aspects affecting LOS is essential for the management of an ED and for implementing improvement interventions. The aim of this study is to determine the several factors affecting LOS in EDs and to build a model capable of predicting ED-LOS through different machine learning (ML) models. ML algorithms were performed considering data extracted from the ED database of the “San Giovanni di Dio e Ruggi d'Aragona” University Hospital (Salerno, Italy). The proposed prediction model shows promising outcomes and therefore it can be used for the prediction and governance of the ED-LOS, thus anticipating the occurrence of overcrowding and improving ED care and efficiency.
急诊科人满为患是近年来公认的影响国际公共卫生的一个关键问题,其原因是卫生保健供需失衡加剧以及医院病房和急诊科床位不足。急诊科住院时间(ED-LOS)被认为是衡量急诊科瓶颈的一个有价值的关键指标,特别是衡量病人获得护理的速度和过度拥挤的情况。ED- los衡量患者从首次登记和分诊到进入医院病房或出院在急诊室停留的时间。延长ED-LOS与不良后果相关,如护理质量和患者满意度降低、死亡风险增加和经济损失。了解影响LOS的各个方面对于ED的管理和实施改进干预措施至关重要。本研究的目的是确定影响ed中LOS的几个因素,并通过不同的机器学习(ML)模型建立一个能够预测ED-LOS的模型。ML算法考虑从“San Giovanni di Dio e Ruggi d'Aragona”大学医院(Salerno, Italy)的ED数据库中提取的数据。所提出的预测模型结果良好,可用于ED- los的预测和治理,从而预测过度拥挤的发生,提高ED的护理和效率。
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引用次数: 1
The Survey of Image Generation from EEG Signals based on Deep Learning 基于深度学习的脑电信号图像生成研究进展
Delong Yang, Dongnan Su, Zhaohui Luo, Peng Shang, Zhigang Hu
China has become a high-risk region of stroke. Most patients with stroke suffer regular bouts of post-stroke limb dyskinesia. Nowadays, there isn’t an effective treatment for these patients. Brain computer interface (BCI) establishes a new pathway to connect human brains and device, which provide an innovation method to repair the human brain nervous systems through rehabilitation training. However, one of the mainly brain activity recordings, Electroencephalogram (EEG), cannot be represented accurately by other algorithms. With the development of deep learning techniques, the topic of EEG signals’ representation by image generation technique has become an important research area. This paper we introduced the basic concepts of BCI systems first, then we give a survey of image generation techniques from EEG signals. At last, we proposed an experimental scheme of dataset establishment which is used for post-stroke patients with upper limb dyskinesia
中国已成为中风高发地区。大多数中风患者在中风后都会出现肢体运动障碍。目前,对这些病人还没有有效的治疗方法。脑机接口(BCI)建立了连接人脑与设备的新途径,为通过康复训练修复人脑神经系统提供了一种创新方法。然而,主要的脑活动记录之一,脑电图(EEG),不能被其他算法准确地表示。随着深度学习技术的发展,利用图像生成技术对脑电信号进行表征已成为一个重要的研究领域。本文首先介绍了脑机接口系统的基本概念,然后对脑电信号图像生成技术进行了综述。最后,我们提出了一种用于脑卒中后上肢运动障碍患者数据集建立的实验方案
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引用次数: 0
Study of Weight-bearing Capacity and Limit of Stability on Ankle Instability after Applying Kinesio Taping Technique 肌内效贴敷技术对踝关节不稳的负重及稳定性限制研究
T. Jaysrichai, Apinan Pasuta, Vorachat Pleankarom, Savit Asavadechsakdi
Abstract. Objective To compare weight-bearing capacity (WBC) and Limit of stability (LOS) between pre- and post- Kinesio Taping application on the pathologic side in persons with ankle instability. Methods Twenty-six participants with ankle instability were recruited. Participants, who performed routine exercise activities, had an average age of 19.07±1.41 years. These participants were tested using Cumberland Ankle Instability Tool (CAIT) (Thai version) and attained t the score less than equal to 27 points. Also, they were tested WBC using the Wireless Weight-Shifting Detector (WWSD; in kilograms) device and to be tested LOS (in centimeters) with Modified Star Excursion Balance (MSEB) test on anterior, posteromedial and posterolateral directions. These participants were applied the Kinesio Taping with the muscle correction and the mechanical correction technique. Afterwards, they repeated the protocol testing for measuring WBC and LOS. The weight-bearing data (kg) and distance (cm) from the MSEB test were calculated to percentage difference (in percent). Results This study revealed that Kinesio Taping application could help to improve the performance on weight-bearing and ankle stability. The average percentage difference of WBC values was increased to 2.52±4.80 percent and the average percentage difference of LOS on posteromedial direction and posterolateral direction were increased to be 12.28±12.54 and 5.82±7.68 percent, respectively. Conclusion Kinesio Taping with muscle correction and mechanical correction techniques on ankle instability can help to improve the WBC and LOS.
摘要目的比较踝关节不稳患者病理侧肌内效贴敷前后的负重能力(WBC)和稳定极限(LOS)。方法选取踝关节不稳患者26例。参与者进行常规运动活动,平均年龄为19.07±1.41岁。这些参与者使用坎伯兰踝关节不稳定工具(CAIT)(泰国版)进行测试,得分小于等于27分。此外,他们还使用无线移重检测器(WWSD;用改良星偏移平衡(MSEB)测试前、后内侧和后外侧方向的LOS(厘米)。这些参与者应用肌内效贴带配合肌肉矫正和机械矫正技术。之后,他们重复了测量WBC和LOS的协议测试。从MSEB试验的负重数据(kg)和距离(cm)计算到百分比差(百分数)。结果肌内效贴敷可以提高负重和踝关节稳定性。WBC值的平均差值百分比增加到2.52±4.80%,后内侧方向和后外侧方向LOS的平均差值百分比分别增加到12.28±12.54和5.82±7.68%。结论肌内修贴联合肌肉矫正和机械矫正技术对踝关节不稳定有改善WBC和LOS的作用。
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引用次数: 0
Self-correction in protoacoustic range verification for different proton pulse widths 不同质子脉冲宽度原声距离验证的自校正
Jiadong Li, P. Tan, Lige Zhang
In proton therapy, the acoustic waves produced by the proton radiation can be measured to determine the proton range. The k-Wave MATLAB toolbox is used to simulate the propagation process of pressure waves in time and space. By measuring the time-of-flight (TOF) of the pressure wave, the Bragg peak distance is obtained. In this study, we obtain the error maps for different pulse widths, which show that angle is the influencing factor of protoacoustic TOF range calculations. To reduce the systematic errors, the angle θ (θ is the angle between the proton beam direction and the vector passing Bragg peak and the sensor) is mapped to the systematic error using a fifth-order polynomial to obtain the correction factor, . The presented simulations show that by correcting the distance with , the systematic error of protoacoustic range verification can be controlled within 1mm under different proton pulses widths.
在质子治疗中,可以测量由质子辐射产生的声波来确定质子的范围。利用k-Wave MATLAB工具箱模拟了压力波在时间和空间上的传播过程。通过测量压力波的飞行时间(TOF),得到了压力波的布拉格峰距离。在本研究中,我们得到了不同脉冲宽度下的误差图,这表明角度是原声TOF距离计算的影响因素。为了减小系统误差,利用五阶多项式将角度θ (θ为质子束方向与通过Bragg峰的矢量与传感器之间的夹角)映射到系统误差上,得到校正因子。仿真结果表明,在不同质子脉冲宽度下,通过对距离进行校正,原声距离验证的系统误差可以控制在1mm以内。
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引用次数: 0
Healthcare Associated Infections in the Neonatal Intensive Care Unit of the “Federico II” University Hospital: Statistical Analysis and Study of Risk Factors “费德里科二世”大学医院新生儿重症监护病房的卫生保健相关感染:危险因素的统计分析和研究
E. Montella, R. Alfano, A. Sacco, Carlo Bernardo, Ilaria Ribera, M. Triassi, A. M. Ponsiglione
Healthcare-associated infections (HAIs) are a common complication among hospitalized patients and an important cause of mortality and morbidity in Neonatal Intensive Care Unit (NICU). New technologies have significantly improved the neonatal survival rate, while causing an increase in the spread of infections. Contracting HAIs means an increase in hospital days, specific drug therapy and greater care that translate into increased costs. Understanding the main risk factors in neonates can help prevent their spread. In this study conducted at the NICU of the “Federico II” University Hospital of Naples in 2019, statistical analysis and logistic regression were used to analyze the association between blood-stream HAIs (BSIs) and the available risk factors. The analysis showed that birthweight and central line catheterization days are significant predictors of suffering from BSIs.
医疗保健相关感染(HAIs)是住院患者中常见的并发症,也是新生儿重症监护病房(NICU)死亡率和发病率的重要原因。新技术大大提高了新生儿存活率,同时也增加了感染的传播。签订卫生保健服务合同意味着住院天数的增加、特定药物治疗和更优质的护理,这些都转化为成本的增加。了解新生儿的主要危险因素有助于防止其传播。本研究于2019年在那不勒斯“费德里科二世”大学医院NICU进行,采用统计分析和logistic回归分析血流HAIs (bsi)与可用危险因素之间的关系。分析表明,出生体重和中线置管天数是患bsi的重要预测因素。
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引用次数: 3
Awareness of food-drug interactions (FDIs) among Jordanian Dietitians 约旦营养师对食品药物相互作用(FDIs)的认识
Natasha Bajj, D. Sweidan, Marry Rose Awies, Julia Barakat, Hiba F. Al-Sayyed
Food and Drug Interactions (FDIs) are one of the most serious problems encountered by the patient as well as by the health care team. FDI can affect patients’ health, especially the most susceptible ones. Dietitians should have adequate information on FDIs since this affects dietary management. To the best of the investigators’ knowledge, so far, no studies have evaluated the awareness of dietitians in the field of FDIs. This investigation is the first study on awareness of Jordanian dietitians on FDIs. Awareness is investigated usually by knowledge, attitudes, and practices. A questionnaire was developed to test awareness parameters of Jordanian dietitians regarding FDIs. The questionnaire was validated and tested for reliability. The questionnaire consisted of 4 parts i.e., sociodemographic characteristics, knowledge, attitude, and practice questions. The questionnaire was distributed to a convenient sample of 360 Jordanian dietitians. The questionnaire was valid and had a satisfactory reliability (Cronbach's-alpha value = 0.622). Jordanian dietitians scored between 0 and 36 out of 39. The mean, median, and standard deviation values of awareness were 23.45, 24.00, and 5.468 indicating very good awareness of FDIs by dietitians. The awareness of Jordanian dietitians towards DRIs should be improved by emphasizing this subject within books and magazines, scientific books in medicine, internet, social media, scientific articles, medical representatives, manufacturers websites, as well as dietitians.
食品和药物相互作用(FDIs)是患者和卫生保健团队遇到的最严重的问题之一。外国直接投资可以影响病人的健康,尤其是最易受影响的病人。营养师应该有足够的外国直接投资信息,因为这影响到饮食管理。据调查人员所知,到目前为止,还没有研究评估过营养师在外国直接投资领域的意识。本调查是第一次对约旦营养师对外国直接投资的认识进行研究。意识通常是通过知识、态度和实践来调查的。制定了一份调查问卷,以测试约旦营养师对外国直接投资的认识参数。对问卷进行了验证和信度测试。问卷由社会人口学特征、知识、态度和实践四部分组成。问卷被分发给360名约旦营养师作为方便样本。问卷有效,信度满意(Cronbach’s-alpha值= 0.622)。在39名营养师中,约旦营养师的得分在0到36之间。知知度的平均值、中位数和标准差分别为23.45、24.00和5.468,表明营养师对外国直接投资的知知度非常高。通过在书籍和杂志、医学科学书籍、互联网、社交媒体、科学文章、医疗代表、制造商网站以及营养师中强调这一主题,应该提高约旦营养师对DRIs的认识。
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引用次数: 0
Probabilistic machine learning methods for Down syndrome prenatal screening: unified first and second trimester markers multivariate bayesian risk model versus current contingent sequential strategy 唐氏综合征产前筛查的概率机器学习方法:统一的妊娠早期和中期标记多变量贝叶斯风险模型与当前偶然顺序策略
Luis M Lopez-Garcia, A. Bataller-Calatayud, Concha Sanz-Marti, Antonio V Antoli-Frances
The aim of the study is to compare performance of a multivariate bayesian model to estimate Down syndrome (DS) risk from a dataset containing biochemical and ultrasound parameters used in first and second-trimester prenatal screening with current contingent sequential screening strategy in the diagnostic of cases missed in first-trimester screening. Methods: observational study in a retrospective way of collecting data from pregnant women who attended the Lluís Alcanyís, Ribera de Alzira y Verge dels Lliris de Alcoy hospitals in Valencia -Spain- for a period of 10 years (2010-2020). Multivariate normal distributions for affected and unaffected fetuses, specified by the means and the covariance matrix of biochemical and ultrasound parameters were set up. Area under the curve (AUC) of ROC (receiver operating characteristic) for classification of DS missed in first trimester screening was the figure to compare by DeLong test the diagnostic performance of quadratic discriminant analysis from this multivariate Bayesian model to current Naïve-Bayes strategy. Results: no significant differences were found between both strategies. Other than second-trimester biometric variables between them, no relevant correlation between the rest of markers was found. Conclusion: accuracy of other machine learning strategies should be investigated, namely artificial neural network, to improve the identification of first trimester undetected cases.
该研究的目的是比较多变量贝叶斯模型的性能,以估计唐氏综合征(DS)的风险,该模型来自一个包含生化和超声参数的数据集,该数据集用于妊娠早期和中期产前筛查,而当前的随机顺序筛查策略用于诊断妊娠早期筛查中遗漏的病例。方法:观察性研究以回顾性的方式收集在西班牙瓦伦西亚Lluís Alcanyís, Ribera de Alzira y Verge dels Lliris de Alcoy医院就诊的孕妇的数据,为期10年(2010-2020)。建立受影响胎儿和未受影响胎儿的多变量正态分布,由生化和超声参数的均值和协方差矩阵指定。ROC (receiver operating characteristic)曲线下面积(Area under the curve, AUC)为早期妊娠筛查漏诊DS的分类图,通过DeLong检验比较该多元贝叶斯模型与目前Naïve-Bayes策略二次判别分析的诊断性能。结果:两种策略间无显著差异。除中期妊娠生物特征变量外,其余指标间无相关性。结论:应进一步研究其他机器学习策略的准确性,即人工神经网络,以提高对早期妊娠未发现病例的识别。
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引用次数: 1
期刊
2021 International Symposium on Biomedical Engineering and Computational Biology
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