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2021 International Symposium on Biomedical Engineering and Computational Biology最新文献

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Hospital activities and CoViD-19: the case study of a Urology Department 医院活动与CoViD-19:以泌尿外科为例
I. Loperto, A. Borrelli, Michele Sparano, M. Triassi
The CoViD-19 pandemic is an international public health emergency. The management of the hospitals found themselves facing an ever-increasing demand for beds, especially for intensive care, thus having to make critical decisions in a short time. A shared action was to block elective surgery deemed deferrable and to transfer resources to the management of the pandemic. The activity of the surgical departments has therefore undergone substantial alterations. In this study, logistic regression and statistical analysis was used to characterize this difference for the Urology Department in "San Giovanni di Dio and Ruggi d'Aragona" University Hospital of Salerno (Italy) by analyzing a set of variables and compared the data obtained in the year 2019, pre-pandemic, with that recorded the following year, in the height of the pandemic. The results show an increased number of emergency hospitalizations as well as scheduled hospitalizations with pre-admission.
新冠肺炎大流行是一场国际突发公共卫生事件。医院的管理人员发现自己面临着日益增长的床位需求,特别是对重症监护的床位需求,因此必须在短时间内做出关键决定。一项共同行动是阻止被认为可推迟的择期手术,并将资源转移到大流行病的管理上。因此,外科部门的活动发生了实质性的变化。在这项研究中,通过分析一组变量,并将2019年大流行前获得的数据与次年大流行高峰期记录的数据进行比较,采用逻辑回归和统计分析来表征萨勒诺“圣乔瓦尼·迪迪奥和鲁吉·阿拉戈纳”大学医院泌尿科的这一差异。结果显示急诊住院人数和住院前计划住院人数均有所增加。
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引用次数: 0
The evolution of skin tissue engineering: A review on recent trends and advances 皮肤组织工程的演变:最近的趋势和进展综述
Haohong Wu
Skin plays an indispensable role in protection, sensation, temperature regulation and so on. Autologous skin grafting is the main method to treat skin wounds. However, patients with large-scale skin defects often face the problem of insufficient autologous skin, and the emergence of tissue engineering effectively compensates for the lack of skin sources. In recent years, with the efforts of scientists, skin tissue engineering technology has made some progress. In this paper, the development of skin tissue engineering in scaffold materials, seed cells and growth factors are reviewed, hoping to provide reference for the progress of skin tissue engineering.
皮肤在保护、感觉、温度调节等方面起着不可或缺的作用。自体皮肤移植是治疗皮肤创面的主要方法。然而,大面积皮肤缺损患者往往面临自体皮肤不足的问题,组织工程的出现有效地弥补了皮肤来源的不足。近年来,在科学家的努力下,皮肤组织工程技术取得了一定的进展。本文就皮肤组织工程在支架材料、种子细胞和生长因子等方面的研究进展进行综述,希望能为皮肤组织工程的发展提供参考。
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引用次数: 0
Investigation of factors increasing waiting times in the Emergency Departments of “San Giovanni di Dio e Ruggi d'Aragona” Hospital through machine learning 通过机器学习对“圣乔瓦尼迪迪奥鲁吉达阿拉戈纳”医院急诊科等待时间增加的因素进行调查
Cristiana Giglio, C. Lauri, Antonio Della Vecchia, A. Borrelli, Giuseppe Russo, M. Triassi, G. Improta
Emergency Departments (EDs) overcrowding is an acknowledged critical issue affecting international public health in recent years, that arises from both the growth of the health care supply/demand imbalance and the lack of beds available in hospitals wards and EDs. Emergency department length of stay (ED-LOS) is identified as a valuable key measure of EDs bottlenecks, and specifically of the rapidity of access to care for patients and of the overcrowding. ED-LOS measures how long patients stay in the ED from their first registration and triage to their admittance to a hospital ward or their discharge. Prolonged ED-LOS has been associated with adverse outcomes, such as reduced level of quality of care and patient satisfaction, increased risk of mortality and financial loss. Understanding aspects affecting LOS is essential for the management of an ED and for implementing improvement interventions. The aim of this study is to determine the several factors affecting LOS in EDs and to build a model capable of predicting ED-LOS through different machine learning (ML) models. ML algorithms were performed considering data extracted from the ED database of the “San Giovanni di Dio e Ruggi d'Aragona” University Hospital (Salerno, Italy). The proposed prediction model shows promising outcomes and therefore it can be used for the prediction and governance of the ED-LOS, thus anticipating the occurrence of overcrowding and improving ED care and efficiency.
急诊科人满为患是近年来公认的影响国际公共卫生的一个关键问题,其原因是卫生保健供需失衡加剧以及医院病房和急诊科床位不足。急诊科住院时间(ED-LOS)被认为是衡量急诊科瓶颈的一个有价值的关键指标,特别是衡量病人获得护理的速度和过度拥挤的情况。ED- los衡量患者从首次登记和分诊到进入医院病房或出院在急诊室停留的时间。延长ED-LOS与不良后果相关,如护理质量和患者满意度降低、死亡风险增加和经济损失。了解影响LOS的各个方面对于ED的管理和实施改进干预措施至关重要。本研究的目的是确定影响ed中LOS的几个因素,并通过不同的机器学习(ML)模型建立一个能够预测ED-LOS的模型。ML算法考虑从“San Giovanni di Dio e Ruggi d'Aragona”大学医院(Salerno, Italy)的ED数据库中提取的数据。所提出的预测模型结果良好,可用于ED- los的预测和治理,从而预测过度拥挤的发生,提高ED的护理和效率。
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引用次数: 1
Analysis of voluntary departures from the Emergency Department of the hospital AORN “A. Cardarelli” 医院急诊科自愿离职分析。Cardarelli”
A. M. Ponsiglione, Massimo Majolo, G. Longo, Giuseppe Russo, M. Triassi, E. Raiola, G. Improta
The emergency department (ED) is the access point for urgent cases within the health facility. In recent years, however, several factors have led to a massive use of ED as a privileged access method to assistance even for patients who do not need timely treatment. This flow of so-called "non-urgent" cases generates pressure on the ED resources, leading to a considerable increase in waiting times which, in turn, generates an increase in patients who leave the ED before being visited from medical doctors. In this work, we investigate some of the factors that may lead to the decision to leave the ED before the first visit. Data were collected at the hospital A.O.R.N. “A. Cardarelli” of Naples (Italy) and then analyzed through traditional statistical tools and more advanced machine learning algorithms.
急诊部(ED)是卫生设施内紧急病例的接入点。然而,近年来,一些因素导致ED作为一种特权获取方法的大量使用,甚至对不需要及时治疗的患者也是如此。这种所谓的"非紧急"病例的流动对急诊科的资源造成压力,导致等待时间大大增加,这反过来又导致在医生探视之前离开急诊科的病人增加。在这项工作中,我们调查了一些可能导致在第一次就诊前决定离开急诊室的因素。数据是在医院的A.O.R.N. A收集的。然后通过传统的统计工具和更先进的机器学习算法进行分析。
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引用次数: 2
The Survey of Image Generation from EEG Signals based on Deep Learning 基于深度学习的脑电信号图像生成研究进展
Delong Yang, Dongnan Su, Zhaohui Luo, Peng Shang, Zhigang Hu
China has become a high-risk region of stroke. Most patients with stroke suffer regular bouts of post-stroke limb dyskinesia. Nowadays, there isn’t an effective treatment for these patients. Brain computer interface (BCI) establishes a new pathway to connect human brains and device, which provide an innovation method to repair the human brain nervous systems through rehabilitation training. However, one of the mainly brain activity recordings, Electroencephalogram (EEG), cannot be represented accurately by other algorithms. With the development of deep learning techniques, the topic of EEG signals’ representation by image generation technique has become an important research area. This paper we introduced the basic concepts of BCI systems first, then we give a survey of image generation techniques from EEG signals. At last, we proposed an experimental scheme of dataset establishment which is used for post-stroke patients with upper limb dyskinesia
中国已成为中风高发地区。大多数中风患者在中风后都会出现肢体运动障碍。目前,对这些病人还没有有效的治疗方法。脑机接口(BCI)建立了连接人脑与设备的新途径,为通过康复训练修复人脑神经系统提供了一种创新方法。然而,主要的脑活动记录之一,脑电图(EEG),不能被其他算法准确地表示。随着深度学习技术的发展,利用图像生成技术对脑电信号进行表征已成为一个重要的研究领域。本文首先介绍了脑机接口系统的基本概念,然后对脑电信号图像生成技术进行了综述。最后,我们提出了一种用于脑卒中后上肢运动障碍患者数据集建立的实验方案
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引用次数: 0
The effect of CoViD-19 pandemic on the hospitalization of a department of Emergency Surgery 新冠肺炎大流行对某急诊科住院率的影响
Teresa Angela Trunfio, Lucia De Coppi, R. Alfano, A. Borrelli, Giuseppe Ferrucci, P. Gargiulo
CoViD-19 caused a significant alteration of the normal activity of hospital facilities. In particular, the surgical departments have been converted and reprogrammed to cope with the emergency, giving priority to urgent procedures that cannot be deferred. To this must be added the actions implemented by governments, such as the lockdown, which forced people to stay in their homes. In this study it was analyzed how the pandemic and the actions taken to counter the spread of the infection have influenced the activity of the Department of Emergency Surgery of "San Giovanni di Dio and Ruggi d'Aragona" University Hospital in Salerno (Italy). Logistic regression and statistical analysis were used to compare the pre-pandemic data (year 2019) with that recorded at the height of the pandemic (year 2020). The results show that Diagnostic Related Group (DRG) weight and urgent hospitalization increased significantly in 2020.
CoViD-19对医院设施的正常活动造成了重大影响。特别是,外科部门进行了改造和重新规划,以处理紧急情况,优先处理不能推迟的紧急程序。除此之外,还必须加上各国政府采取的行动,比如封锁,迫使人们呆在家里。在这项研究中,分析了大流行和为应对感染传播而采取的行动如何影响萨莱诺(意大利)“圣乔瓦尼·迪迪奥和鲁吉·阿拉戈纳”大学医院急诊外科的活动。使用逻辑回归和统计分析将大流行前(2019年)的数据与大流行高峰期(2020年)的数据进行比较。结果显示,2020年诊断相关组(DRG)权重和急诊住院率均显著上升。
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引用次数: 0
Using Statistical Analysis and Logistic Regression to study the effect of CoViD-19 on hospital activities of the C.O.U. General Surgery and Kidney Transplants 采用统计分析和Logistic回归研究CoViD-19对cou普外科和肾移植医院活动的影响
R. Alfano, I. Loperto, Teresa Angela Trunfio, Cristiana Giglio, Giovanni Rossi, A. Borrelli, A. Scala, P. Gargiulo
Due to the Sars-Cov-2 pandemic, the entire health sector in all countries around the world had to reorganize. It was not only a question of increasing the number of intensive care places, but all other medical specialties also had to rewrite their protocols. In this context, it is interesting to investigate whether these new measures have changed the volume of activity and the way hospital departments work. The aim of this study is precisely to verify what has happened to the Transplantation and Related Surgery Centre of the "San Giovanni di Dio e Ruggi d'Aragona" University Hospital of Salerno. For this reason, data were collected on patients who were admitted in 2019 (pre-pendemic) and 2020. The statistical analysis carried out showed that nothing had changed in this department in 2020.
由于Sars-Cov-2大流行,世界各国的整个卫生部门都不得不进行重组。这不仅是一个增加重症监护病房数量的问题,而且所有其他医学专业也必须重写他们的协议。在这种情况下,调查这些新措施是否改变了活动量和医院部门的工作方式是很有趣的。这项研究的目的正是为了验证萨勒诺“圣乔瓦尼·迪迪奥·鲁吉·达阿拉戈纳”大学医院的移植和相关手术中心发生了什么。为此,收集了2019年(流行病前)和2020年入院患者的数据。进行的统计分析表明,该部门在2020年没有任何变化。
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引用次数: 0
Investigating the impact of age, gender, and comorbid conditions on the prolonged length of stay after endarterectomy 调查年龄、性别和合并症对动脉内膜切除术后住院时间延长的影响
C. Lauri, Teresa Angela Trunfio, Ylenia Colella, A. Lombardi, A. Borrelli, P. Gargiulo
Endarterectomy is a commonly performed surgical procedure for reducing long-term stroke risks. Due to the prolonged Length of Stay (LOS) experienced by patients undergoing endarterectomy, predicting this parameter has become increasingly important for both costs savings and the improvement of the management of beds. This study aims to develop a prediction model of LOS value starting from the clinical data related to patients undergoing endarterectomy, exploiting the potential of several Machine Learning algorithms. Data extracted from the information system of the “San Giovanni di Dio and Ruggi d'Aragona” University Hospital (Salerno, Italy) were considered to perform the analysis. The proposed prediction model shows promising outcomes in estimating the LOS and therefore it can be a significant tool for enhancing the planning of endarterectomy procedures.
动脉内膜切除术是降低长期中风风险的常用外科手术。由于接受动脉内膜切除术的患者会经历较长的住院时间(LOS),因此预测这一参数对于节省费用和改善床位管理变得越来越重要。本研究旨在利用几种机器学习算法的潜力,从动脉内膜切除术患者的临床数据出发,建立LOS值的预测模型。数据提取自“圣乔瓦尼迪迪奥和Ruggi d'Aragona”大学医院(Salerno, Italy)的信息系统进行分析。所提出的预测模型在估计LOS方面显示出有希望的结果,因此它可以成为加强动脉内膜切除术手术计划的重要工具。
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引用次数: 1
Investigating the impact of CoViD-19 on the activities of a Department of General Medicine 调查CoViD-19对普通医学部活动的影响
A. Scala, Lucia De Coppi, I. Loperto, A. Borrelli, A. Lombardi, M. Triassi
CoViD-19 has placed the health systems of many countries in further crisis. The elective surgeries were canceled and the staff of several departments, including general medicine, underwent a reallocation to deal with the health emergency. In a context of economic fragility, in recent years the use of indicators for measuring health quality and performance has acquired more and more importance. Access limited only to emergency-urgency cases within hospitals has however produced a benefit in improving the appropriateness of admissions. In this study the value of parameter sets obtained in year 2019 (pre-pandemic) and year 2020 (during the pandemic), including Length of Stay and Diagnostic Related Group (DRG) Weight, of the Department of General Medicine of the University Hospital of Salerno 'San Giovanni di Dio e Ruggi D'Aragona' in Salerno (Italy) were compared using statistical analysis and logistic regression. The statistical analysis shows an increase in the DRG Weight in 2020, so an increase of the complexity of the cases treated and a greater appropriateness of hospitalizations.
CoViD-19使许多国家的卫生系统陷入进一步的危机。选择性手术被取消,包括普通医学在内的几个部门的工作人员进行了重新分配,以处理紧急卫生情况。在经济脆弱的背景下,近年来使用衡量卫生质量和绩效的指标变得越来越重要。然而,仅限于医院内急诊病例的准入在改善入院的适当性方面产生了好处。本研究采用统计分析和logistic回归方法比较了意大利萨莱诺萨莱诺大学医院“圣乔瓦尼迪迪奥和鲁吉达阿拉戈纳”综合医学科2019年(大流行前)和2020年(大流行期间)获得的参数集值,包括住院时间和诊断相关组(DRG)权重。统计分析显示,2020年DRG权重增加,因此治疗病例的复杂性增加,住院治疗更加适当。
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引用次数: 0
Modelling the length of hospital stay in medicine and surgical departments 模拟内科和外科的住院时间
Antonella Fiorillo, Ilaria Picone, I. Latessa, A. Cuocolo
Healthcare Associated Infections are among the world's leading public health problems and the most serious complications for hospitalized patients that can impact length of stay (LOS). In this work, medical record data of 24365 patients admitted to general surgery and clinical medicine wards were used collectively with the aim of creating models capable of predicting overall LOS, measured in days, considering clinical information. Multiple linear regression analysis was performed with IBM SPSS, the coefficient of determination (R2) was equal to 0,288. A regression analysis with ML algorithms was performed with the Knime Analysis Platform. The R2 were quite low for both multiple linear regression and ML regression analyses. The use of these techniques showed that there is a relationship between clinical variables and overall LOS. The results constitute a valid support tool for decision makers to provide the turnover index for the benefit of health policy in the management of departments.
医疗保健相关感染是世界上主要的公共卫生问题之一,也是影响住院时间的最严重并发症。在这项工作中,24365名普通外科和临床医学病房住院患者的病历数据被集体使用,目的是创建能够预测总体LOS的模型,以天为单位,考虑到临床信息。采用IBM SPSS进行多元线性回归分析,决定系数(R2) = 0,288。在Knime分析平台上使用ML算法进行回归分析。多元线性回归和ML回归分析的R2都很低。这些技术的使用表明临床变量与总体LOS之间存在关系。研究结果为决策者提供科室卫生政策效益的周转指标提供了有效的支持工具。
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引用次数: 0
期刊
2021 International Symposium on Biomedical Engineering and Computational Biology
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