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Correlation of Early Cognitive Impairment in Intracerebral Haemorrhage from Tertiary Care Hospital of North Karnataka 北卡纳塔克邦三级医院脑出血患者早期认知功能障碍的相关性
Pub Date : 2024-01-05 DOI: 10.36347/sasjm.2024.v10i01.003
Dhananjaya M, Kiran Hukkeri, Sharankumar Sharankumar, Manoj Manoj
Objectives: To identify the correlation of early cognitive impairment following intracerebral haemorrhage. Methods: A total of 30 adult patients (>15 years) with intracerebral hemorrhage were enrolled in the study. Demographic profile, clinical and radiological profile of the patients was noted. Cognitive status at discharge was assessed using Montreal Cognitive Assessment (MoCA). Results: Mean age was 63.53±12.11 years. Majority were males (56.7%). All the patients had cognitive impairment - majority (76.7%) had moderate cognitive impairment followed by severe impairment (16.7%) and mild impairment (6.7%) respectively at time of discharge. History of tobacco use showed a significant association with severe cognitive impairment. Conclusions: Mild to moderate cognitive impairment is quite frequent among intracerebral hemorrhage patients at time of discharge irrespective of the clinical, demographic and radiological profile.
研究目的确定脑出血后早期认知障碍的相关性。研究方法研究共纳入 30 名成年脑出血患者(大于 15 岁)。研究人员记录了患者的人口统计学特征、临床和放射学特征。出院时的认知状况由蒙特利尔认知评估(MoCA)进行评估。研究结果平均年龄为(63.53±12.11)岁。男性居多(56.7%)。所有患者出院时均存在认知功能障碍,其中大多数患者(76.7%)存在中度认知功能障碍,其次分别为重度(16.7%)和轻度(6.7%)认知功能障碍。烟草使用史与严重认知障碍有显著关联。结论无论临床、人口统计学和放射学特征如何,脑出血患者出院时出现轻度至中度认知功能障碍的情况相当普遍。
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引用次数: 0
Knowledge, Attitude, Acceptance, and Perceived Risks of COVID-19 Vaccines among Pregnant Women: Findings and Implications 孕妇对 COVID-19 疫苗的了解、态度、接受程度和感知风险:调查结果和影响
Pub Date : 2024-01-02 DOI: 10.36347/sasjm.2024.v10i01.002
Steward Mudenda, Gastone Tembo, R. Mfune, Patrick Banda, M. Kasanga, McLawrence Phiri, V. Daka, Billy Chabalenge, Jimmy M. Hangoma
Introduction: COVID-19 vaccines are essential in reducing symptoms and severity of the disease as well as preventing infection with COVID-19. Vaccination of pregnant women against COVID-19 has been recommended globally. In Zambia, there is a paucity of information on the knowledge, attitude, acceptance, and perceived risks of COVID-19 vaccines among pregnant women. Therefore, this study assessed the knowledge, attitude, acceptance, and perceived risks of COVID-19 vaccination among pregnant women attending antenatal care at Women and Newborn Hospital (WNH) of the University Teaching Hospitals (UTHs) in Lusaka, Zambia. Methods: This was a descriptive cross-sectional study conducted from August 2023 to October 2023 among 300 pregnant women attending antenatal care at Women and Newborn Hospital in Lusaka, Zambia. Data were collected using a structured questionnaire and analysed using Statistical Package for Social Science (SPSS) version 23.0. The Chi-square test was used to test the relationship between the dependent and independent variables. The statistical significance was at a 95% confidence level. Results: Of the 300 participants, 186 (62.0%) were aged between 24 and 34 years and 185 (61.5%) were aware that the COVID-19 vaccine was recommended in pregnancy. Overall, 284 (94.7%) had good knowledge, 258 (86.0%) had a positive attitude, and 186 (62.0%) were vaccinated. Additionally, 20 (17.5%) who were not vaccinated were willing to be vaccinated. Furthermore, most of the participants felt that COVID-19 vaccines were safe to use in pregnancy. The results show a lower vaccine acceptance compared to the knowledge and attitude levels. Having good knowledge and a positive attitude was associated with education status (X^2=33.011, p=0.001 for knowledge level) and (X^2=9.132, p=0.029 for attitude level). Conclusion: This study found that pregnant women attending antenatal care at WNH had good knowledge, positive attitudes, good perceptions, and high acceptance of ..........
导言:COVID-19 疫苗对于减轻疾病症状和严重程度以及预防感染 COVID-19 至关重要。全球都建议孕妇接种 COVID-19 疫苗。在赞比亚,有关孕妇对 COVID-19 疫苗的知识、态度、接受程度和感知风险的信息很少。因此,本研究评估了在赞比亚卢萨卡大学教学医院(UTHs)妇女和新生儿医院(WNH)接受产前护理的孕妇对 COVID-19 疫苗接种的知识、态度、接受度和感知风险。研究方法这是一项描述性横断面研究,于 2023 年 8 月至 2023 年 10 月在赞比亚卢萨卡妇女和新生儿医院的 300 名产前护理孕妇中进行。研究使用结构化问卷收集数据,并使用 23.0 版社会科学统计软件包(SPSS)进行分析。采用卡方检验法检验因变量和自变量之间的关系。统计显著性为 95% 的置信水平。结果在 300 名参与者中,186 人(62.0%)的年龄在 24 岁至 34 岁之间,185 人(61.5%)知道 COVID-19 疫苗被推荐在孕期接种。总体而言,284 人(94.7%)对该疫苗有很好的了解,258 人(86.0%)持积极态度,186 人(62.0%)接种了该疫苗。此外,20 名(17.5%)未接种疫苗的人愿意接种疫苗。此外,大多数参与者认为 COVID-19 疫苗在孕期使用是安全的。结果显示,与知识和态度水平相比,人们对疫苗的接受程度较低。良好的知识水平和积极的态度与受教育程度有关(知识水平为 X^2=33.011,p=0.001),与态度水平有关(态度水平为 X^2=9.132,p=0.029)。结论本研究发现,在 WNH 接受产前护理的孕妇对 .......... 有良好的了解、积极的态度、良好的认知和较高的接受度。
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引用次数: 0
Supraventricular Tachycardia: Experience of the Sheikh Khalifa Hospital 室上性心动过速:谢赫-哈利法医院的经验
Pub Date : 2024-01-02 DOI: 10.36347/sasjm.2024.v10i01.001
Najlae Elyounoussi, I. Bensahi, Sara Hafid, Ghita Bennis, Fatimazahra Merzouk, R. Habbal
Introduction: Supraventricular tachycardias represent a fairly common condition, often encountered in emergencies but which remains underestimated due to the rarity of seizures or their atypical manifestations. Methods: We report the results of a retrospective and descriptive single-center study of 32 cases of supraventricular tachycardia carried out in the cardiology department of the Cheikh Khalifa University Hospital over a period of 2 years: from January 2020 to January 2022.We studied in this work the epidemiological, clinical, paraclinical and therapeutic characteristics of these tachycardias. The results of our series are compared with those of the literature. Results: The age of the patients varies between 27 and 80 years with an average age of 58.1 years with a sex ratio M/F=1.6. All patients were symptomatic with the presence of palpitations in 87.5% of cases accompanied by dyspnea in 40.62% of cases, Chest pain and lipothymia were present in 15.62% and Syncope was found in 2 patients 6.25% of cases. Endocavitary electrophysiological exploration has proven to be important in defining the mechanism of these tachycardias, in this case tachycardias with one-to-one conduction; In our series, it confirmed the presence of a typical atrial flutter in 53% of cases, and objectified tachycardia by intranodal reentry in 28.12% of cases and less frequently reentry by accessory route, identified in 18.75% of cases. In this series, radiofrequency represents the energy most used in the management of these supraventricular tachycardias. Conclusion: Conventional fluoroscopy was the most widely used given the typical nature of these SVTs (84.6% of cases) while three-dimensional mapping was only used in 12.5% of patients who were admitted for recurrences. The low risk of complications and the high success rates revealed in our series make ablation a reference treatment, which has made it possible to change the prognosis of supraventricular tachycardias.
导言室上性心动过速是一种相当常见的病症,经常在急诊中遇到,但由于很少发作或表现不典型,因此一直被低估。方法:我们报告了谢赫-哈利法大学医院心内科在 2020 年 1 月至 2022 年 1 月的两年时间里对 32 例室上性心动过速病例进行回顾性和描述性单中心研究的结果。我们对这些心动过速的流行病学、临床、辅助临床和治疗特点进行了研究,并将研究结果与文献进行了比较。结果:患者年龄在 27 至 80 岁之间,平均年龄为 58.1 岁,男女性别比为 1.6。所有患者均无症状,87.5%的病例伴有心悸,40.62%的病例伴有呼吸困难,15.62%的病例伴有胸痛和脂溢性胸痛,2 名患者出现晕厥,占病例总数的 6.25%。事实证明,腔内电生理检查对确定这些心动过速的机制非常重要,在本病例中,心动过速具有一对一的传导机制;在我们的系列研究中,53%的病例证实存在典型的心房扑动,28.12%的病例证实心动过速是由结内再入引起的,18.75%的病例证实是由从属途径引起的再入性心动过速。在这一系列病例中,射频是治疗这些室上性心动过速最常用的能量。结论鉴于这些室上性心动过速的典型性质,传统透视技术的应用最为广泛(占 84.6% 的病例),而三维绘图技术仅用于 12.5% 因复发而入院的患者。我们的系列研究显示,消融术的并发症风险低、成功率高,是一种参考性治疗方法,可以改变室上性心动过速的预后。
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引用次数: 0
Bilateral Peripheric Ulcerative Keratitis Discovered in the Setting of a Pituitary Macroadenoma 垂体大腺瘤时发现的双侧周边溃疡性角膜炎
Pub Date : 2023-12-19 DOI: 10.36347/sasjm.2023.v09i12.006
Boumaazisara Boumaazisara, Belghmaidi Sara, Hajji Ibtissam, Moutaouakil Abdeljalil
We report the case of a 76 years old patient with a long standing history of rheumatoid arthritis, in whom an ophthalmologic asessement for a pituitary macroadenoma led to the discovery of a bilateral Peripheric ulcerative keratitis.
我们报告了一例 76 岁患者的病例,该患者长期患有类风湿性关节炎,眼科检查发现其患有垂体大腺瘤,结果发现其患有双侧外周溃疡性角膜炎。
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引用次数: 0
Anti-Cancer: Principles of use and Management of Side Effects 抗癌:使用原则和副作用管理
Pub Date : 2023-12-16 DOI: 10.36347/sasjm.2023.v09i12.005
N. Nchinech, B. Moukafih, Sanae Achour, Abdesselam Elkartouti, Yassir Bousliman
Today, with the rapid progress we are seeing in the development of new cancer drugs, the importance of pharmacist in the interprofessional oncology team and in the pathway therapy for people with cancer. therefore, the control of principles of use and management of side effects turns out to be crucial. This short communication aims to present the essential points helping the pharmacist in his oncological clinical pharmacy activity.
如今,我们看到新抗癌药物的研发进展迅速,药剂师在跨专业肿瘤团队和癌症患者治疗路径中的重要性日益凸显。本短文旨在介绍有助于药剂师开展肿瘤临床药学活动的要点。
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引用次数: 0
Subacromial Balloon Spacer in Massive Irreparable Rotator Cuff Tears – What Does the Evidence Say? 肩峰下球囊垫片治疗无法修复的肩袖大面积撕裂--证据确凿吗?
Pub Date : 2023-12-11 DOI: 10.36347/sasjm.2023.v09i12.004
Mestre, Pedro Guimarães, Brazão, Carla, Climent-Peris, Vicente
The rupture of the rotator cuff is a common condition in Orthopedics, with massive and irreparable tears posing a challenge for Orthopedic surgeons. There are multiple techniques described for its treatment, with one of the most recent being the implantation of a subacromial balloon. This technically simple technique has shown good biomechanical results in the literature but controversial clinical outcomes. Most of the existing literature is of low scientific evidence. Studies with higher evidence are starting to emerge, but there is still no clear definition of the role of subacromial balloons.
肩袖断裂是矫形外科的常见病,大面积和不可修复的撕裂给矫形外科医生带来了挑战。目前有多种治疗方法,其中最新的一种是植入肩峰下球囊。这种技术简单的技术在文献中显示出良好的生物力学效果,但临床结果却存在争议。大多数现有文献的科学证据不足。有较高证据的研究开始出现,但对肩峰下球囊的作用仍没有明确的定义。
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引用次数: 0
Hypokalemic Nephropathy: Case Report 低钾血症肾病:病例报告
Pub Date : 2023-12-09 DOI: 10.36347/sasjm.2023.v09i12.003
Clément Havyarimana, H. Bothard, Abdelhadi Cheggali, Sara Cheikh, Jean Claude Manirakiza, Nassima Hissein Abdel Aziz, Abdouramane Garba, G. Medkouri, S. Khayat, N. Mtiou, M. Zamd, M. Benghanem
Hypokalemic nephropathy is a rare tubulointerstitial disorder due to chronic hypokalemia that can lead to serious morphological or functional renal alterations. We report a case of a 31-year-old patient from North Africa, admitted to the Department of Nephrology for exploration of proteinuria at 1.2g/24h associated with renal failure at 21mg/l of plasma creatinine in a context of chronic hypokalemia around 2.5mEq/l. The nephropathy check up didn’t show anything particular. The renal biopsy performed revealed renal tubes with vacuolation of the epithelium, with the presence of a few hyaline casts. The interstitial tissue showed minimal fibrosis and a moderate inflammatory infiltrate composed of lymphocytes and histiocytes, all easing the diagnosis of hypokalemic nephropathy. The patient was treated with potassium supplementation in combination with an angiotensin converting enzyme inhibitor (ACE inhibitor). The evolution was marked by a progressive improvement of renal function going from an glomerular filtration rate (GFR) of 28 ml/min (at admission) to 55 ml/min after 6 months, with negativation of proteinuria. Although the hypokalemic nephropathy seems to have disappeared, it must be considered in the face of any alteration of renal function in a context of chronic hypokalemia. Histology is essential to confirm the diagnosis.
低钾血症性肾病是一种罕见的肾小管间质疾病,由慢性低钾血症引起,可导致严重的肾脏形态或功能改变。我们报告了一例来自北非的 31 岁患者,因蛋白尿 1.2g/24h,血浆肌酐 21mg/l,肾功能衰竭,慢性低钾血症约 2.5mEq/l,入住肾内科。肾病检查没有发现任何特别之处。肾活检显示肾小管上皮空泡化,存在少量透明铸型。间质组织显示出极少量纤维化以及由淋巴细胞和组织细胞组成的中度炎症浸润,所有这些都使低钾肾病的诊断变得容易。患者在接受补钾治疗的同时,还服用了血管紧张素转换酶抑制剂(ACE 抑制剂)。患者的肾功能逐渐得到改善,肾小球滤过率(GFR)从入院时的 28 毫升/分钟上升到 6 个月后的 55 毫升/分钟,蛋白尿消失。虽然低钾血症肾病似乎已经消失,但在慢性低钾血症的情况下,必须考虑肾功能的任何改变。组织学检查对确诊至关重要。
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引用次数: 0
Local Recurrence of a Mandibular Ameloblastoma: Report Case 下颌骨釉母细胞瘤局部复发:病例报告
Pub Date : 2023-11-30 DOI: 10.36347/sasjm.2023.v09i11.027
Berkaoui Mohamed, Barkiche Samir, Darfaoui Mouna, Elomrani Abdelhamid, Khouchani Mouna
Ameloblastoma is a benign odontogenic tumor with local malignancy due to its propensity to invade all tissues surrounding areas and its risk of recurrence after enucleation; Its preferred anatomical site is mandibular. We present a case of a patient who presents a mandibular ameloblastoma initially treated by surgery then 3 years later he presents a local recurrence confirmed histologically.
釉母细胞瘤是一种良性牙源性肿瘤,具有局部恶性的特点,因为它倾向于侵犯周围的所有组织,而且在切除后有复发的风险;它的首选解剖部位是下颌骨。我们报告了一例下颌骨釉母细胞瘤患者的病例,患者最初接受了手术治疗,3 年后经组织学证实出现局部复发。
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引用次数: 0
Profile of Coronary Artery Disease Patients: A Single Center Study 冠状动脉疾病患者的概况:单中心研究
Pub Date : 2023-11-29 DOI: 10.36347/sasjm.2023.v09i11.026
Md. Abdur Rashid, Sonia Ahmed
Background: Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Analyzing the profile of CAD patients involves exploring various demographic and clinical factors that may influence the occurrence, progression, and management of the disease. This study aimed to analyze the profile of patients with coronary artery disease, focusing on demographic and clinical characteristics. Methods: This prospective observational study was conducted in the Department of Cardiology, 250 Bed General Hospital in Meherpur, Bangladesh, from June 2021 to July 2022. A total of 87 coronary artery disease patients were enrolled in this study as the study subjects. MS Office tools were applied for data analysis. Results: The mean age of the participants was 46.83 ±14.31 years; males were 70%. Approximately one-third of them had a BMI (Kg/m2) of ≥30. The most common symptom was chest pain, present in 70% and the most common complication was mitral regurgitation, affecting 26% of individuals. The predominant risk factors were diabetes mellitus (21%) and hypertension (18%). Angiographic findings revealed normal findings in 37% of patients. Single-vessel disease (SVD) was observed in 28% of cases, while double-vessel disease (DVD) and triple-vessel disease (TVD) were found in 20% and 14% of patients, respectively. Conclusion: Middle-aged male individuals are mainly prone to coronary artery diseases (CAD). For CAD patients, chest pain is the most common symptom, diabetes mellitus and hypertension are predominant risk factors and mitral regurgitation is the most prevalent complication.
背景:冠状动脉疾病(CAD)是全球发病率和死亡率的主要原因。分析冠状动脉疾病患者的概况需要探究可能影响疾病发生、发展和治疗的各种人口和临床因素。本研究旨在分析冠状动脉疾病患者的概况,重点关注人口统计学和临床特征。研究方法这项前瞻性观察研究于 2021 年 6 月至 2022 年 7 月在孟加拉国梅赫布尔 250 床综合医院心脏病科进行。共有 87 名冠心病患者作为研究对象参与了这项研究。数据分析采用 MS Office 工具。研究结果参与者的平均年龄为 46.83 ±14.31 岁,男性占 70%。其中约三分之一的人体重指数(Kg/m2)≥30。最常见的症状是胸痛,占 70%,最常见的并发症是二尖瓣反流,占 26%。最主要的风险因素是糖尿病(21%)和高血压(18%)。37%的患者血管造影结果显示正常。单血管疾病(SVD)占 28%,双血管疾病(DVD)和三血管疾病(TVD)分别占 20% 和 14%。结论中年男性是冠状动脉疾病(CAD)的主要易感人群。对于冠状动脉疾病患者来说,胸痛是最常见的症状,糖尿病和高血压是主要的危险因素,二尖瓣返流是最常见的并发症。
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引用次数: 0
Study of the Relative Frequency of Different Disease in Fever with Thrombocytopenia 发热伴血小板减少不同疾病的相对发生率研究
Pub Date : 2023-11-29 DOI: 10.36347/sasjm.2023.v09i11.024
Mohammed Razzak Mia, A.N.M. Mizanur Rahman, Md. Jashim Uddin, Mohammad Bhuiyan Abdus Samad Azad, Md. Mustofakamal Uddin Khan, Nadim Ahmed
Background: Thrombocytopenia is a common biological sign, and in severe situations, bleeding can ensue. Thrombocytopenia caused mostly by platelet immunological destruction, decreased platelet synthesis in bone marrow, and a delay in megakaryocyte maturation. Dengue fever haemostasis disruption is exacerbated by thrombocytopenia and platelet dysfunction. Objective: To determine the relative prevalence of various diseases in fever with thrombocytopenia. Materials and Methods: This observational, cross-sectional study was carried out by the Department of Medicine at the 100-bed district hospital in Narsingdi between July 2021 and June 2022. Total 100 adult patients (over the age of 18) who had thrombocytopenia and presented with fever were included in this study. We excluded patients who had a fever but no thrombocytopenia. Additionally, patients with thrombocytopenia but no fever were excluded from the research. Results: Malaria was the most prevalent cause of fever (44.0%), followed by dengue (27.0%), viral fever (18.0%), enteric fever (5.0%), dengue + malaria (3.0%), septicemia (2.0%), and hematologic malignancy (1.0%). Conclusion: Dengue fever and malaria are common causes of fever with thrombocytopenia because of seasonal and regional variations.
背景:血小板减少症是一种常见的生物学症状,严重时可导致出血。血小板减少主要由血小板免疫破坏、骨髓中血小板合成减少和巨核细胞成熟延迟引起。血小板减少和血小板功能障碍会加剧登革热止血障碍。目的确定发热伴血小板减少时各种疾病的相对患病率。材料与方法:2021 年 7 月至 2022 年 6 月期间,纳辛迪拥有 100 张病床的地区医院内科开展了这项横断面观察研究。研究共纳入 100 名患有血小板减少症并伴有发烧的成年患者(18 岁以上)。我们排除了发烧但没有血小板减少的患者。此外,研究还排除了血小板减少但没有发烧的患者。研究结果疟疾是最常见的发热原因(44.0%),其次是登革热(27.0%)、病毒性发热(18.0%)、肠热(5.0%)、登革热+疟疾(3.0%)、败血症(2.0%)和血液系统恶性肿瘤(1.0%)。结论由于季节和地区差异,登革热和疟疾是导致发热伴血小板减少的常见原因。
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引用次数: 0
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SAS Journal of Medicine
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