Obesity research & clinical practice最新文献

Objective: To explore the relationship between weight stigma and psychosocial health, and to characterise the extent to which individuals are engaged with weight inclusive (i.e., weight neutral, "non-diet") approaches to health. First, we aimed to (1) estimate whether internalised weight stigma mediated the relationship between experienced weight stigma and psychosocial health and (2) understand the role that awareness, engagement, and endorsement (AEE) of non-diet approaches to health might have in affecting this mediation. All methods were pre-registered (see osf.io/uwf7n).

Methods: Participants (n = 418; M_Age = 36.8, SD = 12.5; M_BMI = 29.5, SD = 6.8) completed an online survey on measures including non-diet AEE, weight stigma, and psychosocial health.

Results: Consistent with hypotheses, weight stigma was positively correlated with adverse psychosocial health. Internalised weight stigma mediated the relationship between experienced weight stigma and all 16 psychosocial health correlates measured, including psychological distress, disordered eating, and intuitive eating (controlling for BMI). AEE of non-diet approaches was associated with external forms of weight stigma, but not internal, self-directed weight stigma (partially supporting hypothesis). Contrary to hypotheses, there were few consistent relationships between non-diet AEE and psychosocial health correlates, and AEE of non-diet approaches to health did not moderate the hypothesised mediation effect.

Conclusion: We found that internalised weight stigma mediated experienced weight stigmas' effects, and that weight stigma was consistently related to adverse psychosocial health. However, the results were mixed for non-diet AEE. At the bivariate level, there was some indication of non-diet AEE's importance, but not at the level of our hypothesised moderating effect.

Introduction: Vitamin D deficiency has been implicated in various metabolic disorders, but its relationship with adiposity and atherogenic risk remains not fully elucidated. We assessed associations between serum vitamin D levels and a wide range of metabolic, atherogenic, and adiposity-related markers in adults stratified by weight status.

Methods: A cross-sectional analysis was conducted on 130 adults categorized according to their body weight status into: normal weight, overweight, and obesity. Additionally, participants were grouped based on serum vitamin D levels (threshold 20 ng/mL) Clinical, metabolic, and anthropometric variables were compared across groups. A principal component analysis (PCA) was applied to explore underlying patterns of association.

Results: As expected, significant differences in cardiometabolic parameters emerged across weight categories (p < 0.05). However, vitamin D levels showed no significant correlation with most metabolic variables in either univariate or multivariate analysis. PCA revealed that vitamin D and body mass index (BMI) were consistently represented as opposing vectors, suggesting distinct but potentially interacting influences on metabolic risk. While BMI was associated with indices such as TG/HDL, atherogenic index of plasma, and cardiometabolic risk index, vitamin D correlated more closely with HDL, total cholesterol, and Triglyceride-Cholesterol Body Index.

Conclusions: Findings indicate that vitamin D may influence cardiometabolic profiles through mechanisms that are at least partially independent of adiposity. Despite the lack of direct correlations, the divergent associations observed in PCA suggest possible interaction effects between BMI and vitamin D. Further longitudinal studies are needed to evaluate vitamin D's role as a context-dependent modulator of metabolic risk.