Pub Date : 2024-07-01DOI: 10.4103/njcp.njcp_259_24
EH Demir Sevinç, CB İnal, C. Aydin
This study aims to investigate color stability and surface roughness of polyetheretherketone (PEEK), zirconia, and hybrid ceramics while stored in different liquids. A total of 240 specimens were prepared from monolithic zirconia, PEEK, and hybrid ceramics. All specimens were polished using rubber sets with different grain sizes. Color parameters (L*, a*, b*) were measured three times using a dental spectrophotometer in standard D65 lightning. Each group was divided into eight different groups to be kept in eight different solutions as distilled water, cola, red wine, tea, coffee, heptane, citric acid, and 50% ethanol. Specimens were held in solutions at 37°C for 12 days. Color measurements were repeated, and color change (ΔE) was calculated using the CIE Lab formula. The color difference of PEEK specimens was found above the clinically acceptable limit; however, color differences for monolithic zirconia produced by coffee were found within the clinically acceptable limits. ZR and HC specimens’ color change values were found between threshold values (1<ΔE < 3.3). The differences observed in surface roughness levels amongst the ZR specimens could be caused by the polishing instrument and procedure. The color change of the materials was within acceptable limits, whereas the surface roughness increased more than 0.2 µm. Especially cola, heptane, and red wine significantly increased the mean surface roughness.
{"title":"In Vitro Evaluation of Color and Surface Roughness Changes of Polyetheretherketone, Monolithic Zirconia, and Resin Nanoceramics Exposed to Staining Liquids","authors":"EH Demir Sevinç, CB İnal, C. Aydin","doi":"10.4103/njcp.njcp_259_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_259_24","url":null,"abstract":"\u0000 \u0000 This study aims to investigate color stability and surface roughness of polyetheretherketone (PEEK), zirconia, and hybrid ceramics while stored in different liquids.\u0000 \u0000 \u0000 \u0000 A total of 240 specimens were prepared from monolithic zirconia, PEEK, and hybrid ceramics. All specimens were polished using rubber sets with different grain sizes. Color parameters (L*, a*, b*) were measured three times using a dental spectrophotometer in standard D65 lightning. Each group was divided into eight different groups to be kept in eight different solutions as distilled water, cola, red wine, tea, coffee, heptane, citric acid, and 50% ethanol. Specimens were held in solutions at 37°C for 12 days. Color measurements were repeated, and color change (ΔE) was calculated using the CIE Lab formula.\u0000 \u0000 \u0000 \u0000 The color difference of PEEK specimens was found above the clinically acceptable limit; however, color differences for monolithic zirconia produced by coffee were found within the clinically acceptable limits. ZR and HC specimens’ color change values were found between threshold values (1<ΔE < 3.3). The differences observed in surface roughness levels amongst the ZR specimens could be caused by the polishing instrument and procedure.\u0000 \u0000 \u0000 \u0000 The color change of the materials was within acceptable limits, whereas the surface roughness increased more than 0.2 µm. Especially cola, heptane, and red wine significantly increased the mean surface roughness.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the realm of healthcare, particularly after the COVID-19 pandemic, there is a rising trend of sharing videos on YouTube. The increased popularity of these videos among Internet users can be attributed to the captivating nature of visual and auditory data compared to written information. This study aims to assess the content, accuracy, reliability, and quality of YouTube videos focusing on defibrillation applications—a critical component of cardiopulmonary resuscitation (CPR). On October 17, 2022, a video search was conducted using the keyword “defibrillation” on the YouTube platform, sorted in order of interest. Various parameters, including views, view rate, duration, comments, total likes and dislikes, target population, JAMA, DISCERN, and GQS scores, were recorded. In addition, content information was evaluated by Emergency Medicine specialists. The average video duration was 263.95 seconds, with an average of 90,574.6 views, 587.4 likes, and 19.1 comments. The mean DISCERN score was 35.9 (poor), modified DISCERN score was 1.7, GQS score was 2.7, and JAMA score was 2. The mean score regarding the scope and detail of information in the videos was calculated as 6.1. Deficiencies in the accuracy and reliability of Internet information were observed, mirroring the findings in our study. Supervision in this regard was often found to be inadequate. We advocate for the evaluation of video appropriateness before sharing on the Internet. We believe that platforms ensuring easy access to accurate information about crucial interventions such as CPR will significantly contribute to improving health literacy.
{"title":"Evaluation of YouTube Videos on Defibrillation Applications in Cardiopulmonary Resuscitation: A Comprehensive Analysis","authors":"İ. Aksoy","doi":"10.4103/njcp.njcp_68_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_68_24","url":null,"abstract":"\u0000 \u0000 In the realm of healthcare, particularly after the COVID-19 pandemic, there is a rising trend of sharing videos on YouTube. The increased popularity of these videos among Internet users can be attributed to the captivating nature of visual and auditory data compared to written information.\u0000 \u0000 \u0000 \u0000 This study aims to assess the content, accuracy, reliability, and quality of YouTube videos focusing on defibrillation applications—a critical component of cardiopulmonary resuscitation (CPR).\u0000 \u0000 \u0000 \u0000 On October 17, 2022, a video search was conducted using the keyword “defibrillation” on the YouTube platform, sorted in order of interest. Various parameters, including views, view rate, duration, comments, total likes and dislikes, target population, JAMA, DISCERN, and GQS scores, were recorded. In addition, content information was evaluated by Emergency Medicine specialists.\u0000 \u0000 \u0000 \u0000 The average video duration was 263.95 seconds, with an average of 90,574.6 views, 587.4 likes, and 19.1 comments. The mean DISCERN score was 35.9 (poor), modified DISCERN score was 1.7, GQS score was 2.7, and JAMA score was 2. The mean score regarding the scope and detail of information in the videos was calculated as 6.1.\u0000 \u0000 \u0000 \u0000 Deficiencies in the accuracy and reliability of Internet information were observed, mirroring the findings in our study. Supervision in this regard was often found to be inadequate. We advocate for the evaluation of video appropriateness before sharing on the Internet. We believe that platforms ensuring easy access to accurate information about crucial interventions such as CPR will significantly contribute to improving health literacy.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/njcp.njcp_880_23
A. Waseem, A. Jamal, A. Qadir, V. Amitabh
In India, cirrhosis is becoming a growing concern, leading to an unmet need for new non-invasive markers to assess the severity of liver disease. Serum prolactin is one such marker. To determine the association between serum prolactin, the severity of liver cirrhosis, and its complications such as ascites, hepatic encephalopathy, and esophageal varices. This cross-sectional study involved 117 patients with liver cirrhosis. They were evaluated for some complications such as ascites, esophageal varices, and hepatic encephalopathy, as well as for severity by using the Child-Turcotte-Pugh (CTP) score. Serum prolactin levels were measured, and their relationship with both the severity and complications of liver cirrhosis was determined. A P value of < 0.05 was considered significant. The mean age of the patients was 48.3 ± 12.08 years, and the majority (80.3%) were males. Seventy-one percent of the patients had elevated serum prolactin levels (>19.40 ng/mL). Elevated serum prolactin was found in approximately 95.0% and 86.8% of patients with hepatic encephalopathy and ascites, respectively. The median serum prolactin levels were significantly associated with esophageal varices grades (P = 0.043) and hepatic encephalopathy (P < 0.001). The sensitivity and specificity of serum prolactin for predicting severe CTP scores were 81.6% and 91.2%, respectively, with a diagnostic accuracy of 87.2%. On multivariate regression analysis, ascites (AOR = 3.8, 95%CI = 1.29–10.98, P = 0.015), hepatic encephalopathy (AOR = 6.1, 95%CI = 0.68–53.78, P = 0.012), CTP class B (AOR = 5.9, 95%CI = 1.39–24.68, P = 0.016), and CTP class C (AOR = 13.4, 95%CI = 2.25–82.21, P = 0.004) were significantly associated with elevated serum prolactin levels. There was a significant association between serum prolactin levels and CTP classes, esophageal varices, ascites, and hepatic encephalopathy in patients with liver cirrhosis.
{"title":"Serum Prolactin as a Marker of the Severity of Liver Cirrhosis in a Tertiary Hospital in India: A Cross-Sectional Study","authors":"A. Waseem, A. Jamal, A. Qadir, V. Amitabh","doi":"10.4103/njcp.njcp_880_23","DOIUrl":"https://doi.org/10.4103/njcp.njcp_880_23","url":null,"abstract":"\u0000 \u0000 In India, cirrhosis is becoming a growing concern, leading to an unmet need for new non-invasive markers to assess the severity of liver disease. Serum prolactin is one such marker.\u0000 \u0000 \u0000 \u0000 To determine the association between serum prolactin, the severity of liver cirrhosis, and its complications such as ascites, hepatic encephalopathy, and esophageal varices.\u0000 \u0000 \u0000 \u0000 This cross-sectional study involved 117 patients with liver cirrhosis. They were evaluated for some complications such as ascites, esophageal varices, and hepatic encephalopathy, as well as for severity by using the Child-Turcotte-Pugh (CTP) score. Serum prolactin levels were measured, and their relationship with both the severity and complications of liver cirrhosis was determined. A P value of < 0.05 was considered significant.\u0000 \u0000 \u0000 \u0000 The mean age of the patients was 48.3 ± 12.08 years, and the majority (80.3%) were males. Seventy-one percent of the patients had elevated serum prolactin levels (>19.40 ng/mL). Elevated serum prolactin was found in approximately 95.0% and 86.8% of patients with hepatic encephalopathy and ascites, respectively. The median serum prolactin levels were significantly associated with esophageal varices grades (P = 0.043) and hepatic encephalopathy (P < 0.001). The sensitivity and specificity of serum prolactin for predicting severe CTP scores were 81.6% and 91.2%, respectively, with a diagnostic accuracy of 87.2%. On multivariate regression analysis, ascites (AOR = 3.8, 95%CI = 1.29–10.98, P = 0.015), hepatic encephalopathy (AOR = 6.1, 95%CI = 0.68–53.78, P = 0.012), CTP class B (AOR = 5.9, 95%CI = 1.39–24.68, P = 0.016), and CTP class C (AOR = 13.4, 95%CI = 2.25–82.21, P = 0.004) were significantly associated with elevated serum prolactin levels.\u0000 \u0000 \u0000 \u0000 There was a significant association between serum prolactin levels and CTP classes, esophageal varices, ascites, and hepatic encephalopathy in patients with liver cirrhosis.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
YR Raji, SO Ajayi, OS Michael, D. Adewole, T. Akande, BI Abiola, OO Aminu, OO Efuntoye, A. Olugbenga-Bello, A. Arije
The outlook of chronic kidney disease (CKD) in low-and-medium-income-countries is poor. Modern farming practices in Nigeria are becoming increasingly associated with the use of herbicides and pesticides. The study aimed to evaluate agrochemical use in farming practices and risk factors for kidney disease among dwellers of rural farming communities in South-West Nigeria. This was a cross-sectional survey of adult dwellers of an agrarian rural farming community in South-West Nigeria. Participants provided information on demographics, lifestyles, knowledge, and awareness of risk factors for kidney disease, and the use of agrochemicals in farming practice. Anthropometric measurements and blood pressure values were obtained while blood and spot urine were collected for random blood glucose, serum creatinine, urinalysis, and albumin-creatinine ratio. A total of 572 rural dwellers were enrolled in the study, with a mean age of 49.9 ± 17.5 years while 39.3% were male and 88.9% engaged in active farming. The prevalence of traditional risk factors for kidney disease was hypertension (24.3%), Diabetes mellitus (2.8%), cigarette smoking (7.5%), alcohol intake (20.8%) and herbal consumption (57.1%). The use of pesticides/herbicides was reported in 69.9%, while 25.3% did not use protective gear during its use. Proteinuria, hematuria, and reduced eGFR were observed in 29.8%, 6.1%, and 33.9% of participants, respectively. This study showed a high prevalence of herbicides and pesticide use and traditional risk factors for kidney disease, in addition to the high prevalence of markers of kidney damage among the dwellers of rural farming settlements in South-West Nigeria.
{"title":"Agrochemical use in Farming Practices and Risk Factors for Kidney Disease among Dwellers of Rural Farming Communities in South-West Nigeria","authors":"YR Raji, SO Ajayi, OS Michael, D. Adewole, T. Akande, BI Abiola, OO Aminu, OO Efuntoye, A. Olugbenga-Bello, A. Arije","doi":"10.4103/njcp.njcp_55_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_55_24","url":null,"abstract":"\u0000 \u0000 The outlook of chronic kidney disease (CKD) in low-and-medium-income-countries is poor. Modern farming practices in Nigeria are becoming increasingly associated with the use of herbicides and pesticides.\u0000 \u0000 \u0000 \u0000 The study aimed to evaluate agrochemical use in farming practices and risk factors for kidney disease among dwellers of rural farming communities in South-West Nigeria.\u0000 \u0000 \u0000 \u0000 This was a cross-sectional survey of adult dwellers of an agrarian rural farming community in South-West Nigeria. Participants provided information on demographics, lifestyles, knowledge, and awareness of risk factors for kidney disease, and the use of agrochemicals in farming practice. Anthropometric measurements and blood pressure values were obtained while blood and spot urine were collected for random blood glucose, serum creatinine, urinalysis, and albumin-creatinine ratio.\u0000 \u0000 \u0000 \u0000 A total of 572 rural dwellers were enrolled in the study, with a mean age of 49.9 ± 17.5 years while 39.3% were male and 88.9% engaged in active farming. The prevalence of traditional risk factors for kidney disease was hypertension (24.3%), Diabetes mellitus (2.8%), cigarette smoking (7.5%), alcohol intake (20.8%) and herbal consumption (57.1%). The use of pesticides/herbicides was reported in 69.9%, while 25.3% did not use protective gear during its use. Proteinuria, hematuria, and reduced eGFR were observed in 29.8%, 6.1%, and 33.9% of participants, respectively.\u0000 \u0000 \u0000 \u0000 This study showed a high prevalence of herbicides and pesticide use and traditional risk factors for kidney disease, in addition to the high prevalence of markers of kidney damage among the dwellers of rural farming settlements in South-West Nigeria.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The management of upper limb injury is aimed at a timely return to work, and other activities of daily living. The modified hand injury severity score (MHISS) has been found to predict a return to work. Upper limb injuries are common in our subregion, but there is little or no data on the time to return to work. This study, therefore, aimed to determine the prevalence of return to work and to identify the predictors of time to return to work following reconstruction of upper limb injuries. This was a cross-sectional analytic study carried out between April 2022 and March 2023. The statistical test was at a confidence interval of 95%, and statistical significance set at a P value of <0.05. A total of 49 upper-limb-injured patients had reconstruction in the time under review. Male-to-female ratio was 4.4:1. The mean MHISS was 87.9 ± 79.2. Of the 43 patients who participated in the return-to-work analysis, 41.9% had returned to work, with a mean time of 14.3 ± 10.5 weeks. Work-related injuries (r = 0.357, P = 0.019), male gender (r = 0.354, P = 0.020), and MHISS (r = 0.333, P = 0.029) correlated significantly with late return to work. On multiple logistic regression, work-related injuries (β =0.321, P = 0.037), MHISS (β =0.376, P = 0.032), and male gender (β =0.326, P = 0.044) were found to be the significant predictors of late return to work. There is a low prevalence of return to work, with a high mean time to return. Work-related injuries, MHISS, and male gender are significant predictors of time to return to work.
{"title":"Predictors of Time to Return to Work Following Surgical Reconstruction of Upper Limb Injuries in a Cosmopolitan City in Western Nigeria","authors":"AI Michael, CP Isamah, IC Ugwu","doi":"10.4103/njcp.njcp_30_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_30_24","url":null,"abstract":"\u0000 \u0000 The management of upper limb injury is aimed at a timely return to work, and other activities of daily living. The modified hand injury severity score (MHISS) has been found to predict a return to work. Upper limb injuries are common in our subregion, but there is little or no data on the time to return to work.\u0000 \u0000 \u0000 \u0000 This study, therefore, aimed to determine the prevalence of return to work and to identify the predictors of time to return to work following reconstruction of upper limb injuries.\u0000 \u0000 \u0000 \u0000 This was a cross-sectional analytic study carried out between April 2022 and March 2023. The statistical test was at a confidence interval of 95%, and statistical significance set at a P value of <0.05.\u0000 \u0000 \u0000 \u0000 A total of 49 upper-limb-injured patients had reconstruction in the time under review. Male-to-female ratio was 4.4:1. The mean MHISS was 87.9 ± 79.2. Of the 43 patients who participated in the return-to-work analysis, 41.9% had returned to work, with a mean time of 14.3 ± 10.5 weeks. Work-related injuries (r = 0.357, P = 0.019), male gender (r = 0.354, P = 0.020), and MHISS (r = 0.333, P = 0.029) correlated significantly with late return to work. On multiple logistic regression, work-related injuries (β =0.321, P = 0.037), MHISS (β =0.376, P = 0.032), and male gender (β =0.326, P = 0.044) were found to be the significant predictors of late return to work.\u0000 \u0000 \u0000 \u0000 There is a low prevalence of return to work, with a high mean time to return. Work-related injuries, MHISS, and male gender are significant predictors of time to return to work.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/njcp.njcp_240_24
MN Namlı, H. Bahadir, O. Oflezer
Schizophrenia is a severe and chronic neuropsychiatric disorder that involves profound impairment of psychopathology in cognition, emotion, perception, and other aspects of behavior. Factors, such as the nature of the disease, length of hospital stay, duration of illness, and side effects of psychotropic drugs, may contribute to poor oral health and the risk of developing bruxism in patients with schizophrenia. To evaluate the prevalence of bruxism and associated factors in patients with schizophrenia. This cross-sectional study was conducted in a single center with 211 patients with schizophrenia. Study participants were graded according to “probable” bruxism based on positive clinical inspection, with or without a positive self-report. The type of antipsychotic treatment used in participants was evaluated in three categories: typical antipsychotic monotherapy, atypical antipsychotic monotherapy, and a combination of both. Binary logistic regression models were used to evaluate associations between probable bruxism and different factors. The mean age of the study participants was 51.02 ± 9.29 years, and 112 (52.5%) were males. Probable bruxism was identified in 87 (41.2%) of the study participants. Younger age (AOR = 0.88, 95% CI = 0.838–0.928, P < 0.001), higher duration of illness (AOR = 1.50, 95% CI = 1.278–7.545, P < 0.001), and combination antipsychotic therapy (AOR = 3.042, 95% CI = 1.278–7.545, P = 0.015) were significant factors associated with probable bruxism among patients with schizophrenia on treatment. The relatively high prevalence of probable bruxism in patients with schizophrenia and its relation to antipsychotics was observed. There is a need for more research on the causes and treatment of bruxism in schizophrenia.
{"title":"The Prevalence of Bruxism and Associated Factors Among Patients with Schizophrenia in Istanbul, Türkiye: A Cross-Sectional Study","authors":"MN Namlı, H. Bahadir, O. Oflezer","doi":"10.4103/njcp.njcp_240_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_240_24","url":null,"abstract":"\u0000 \u0000 Schizophrenia is a severe and chronic neuropsychiatric disorder that involves profound impairment of psychopathology in cognition, emotion, perception, and other aspects of behavior. Factors, such as the nature of the disease, length of hospital stay, duration of illness, and side effects of psychotropic drugs, may contribute to poor oral health and the risk of developing bruxism in patients with schizophrenia.\u0000 \u0000 \u0000 \u0000 To evaluate the prevalence of bruxism and associated factors in patients with schizophrenia.\u0000 \u0000 \u0000 \u0000 This cross-sectional study was conducted in a single center with 211 patients with schizophrenia. Study participants were graded according to “probable” bruxism based on positive clinical inspection, with or without a positive self-report. The type of antipsychotic treatment used in participants was evaluated in three categories: typical antipsychotic monotherapy, atypical antipsychotic monotherapy, and a combination of both. Binary logistic regression models were used to evaluate associations between probable bruxism and different factors.\u0000 \u0000 \u0000 \u0000 The mean age of the study participants was 51.02 ± 9.29 years, and 112 (52.5%) were males. Probable bruxism was identified in 87 (41.2%) of the study participants. Younger age (AOR = 0.88, 95% CI = 0.838–0.928, P < 0.001), higher duration of illness (AOR = 1.50, 95% CI = 1.278–7.545, P < 0.001), and combination antipsychotic therapy (AOR = 3.042, 95% CI = 1.278–7.545, P = 0.015) were significant factors associated with probable bruxism among patients with schizophrenia on treatment.\u0000 \u0000 \u0000 \u0000 The relatively high prevalence of probable bruxism in patients with schizophrenia and its relation to antipsychotics was observed. There is a need for more research on the causes and treatment of bruxism in schizophrenia.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/njcp.njcp_556_23
P. Tamulionis, E. Ostapenko, D. Šeinin, A. Kilius
Schwannoma, also known as neurilemmoma or Schwann cell tumor, is one of the most common neoplasms of the nerve sheath which usually appears at the head, neck, or upper extremity. Schwannoma occurrence in the lower extremity originating from the common peroneal nerve is rarely reported according to literary findings. We report a case of a 32-year-old man who presented with a 6-month history of a growing lump in the left knee. MRT revealed a well-defined 9.6 cm × 7.8 cm × 6.5 cm multilobular mass of heterogeneous consistency with areas of necroses with a likely diagnosis of synovial sarcoma. After surgery, a final histopathological assessment of the tumor demonstrated Antoni A and B patterns with nuclear palisading, hallmarks of a schwannoma. Postoperatively the patient suffered a neurological complication–impaired dorsiflexion of the left foot. The patient started immediate physiotherapy in the Department of Rehabilitation. Three weeks after the operation, gradual improvement in neurological function was observed. To date, complete tumor excision combined with microscopic analysis and immunohistochemical staining remains the gold standard in diagnosing and treating a peripheral nerve schwannoma. Moreover, the use of additional nerve monitoring tools during surgery could help to prevent complications.
许旺瘤又称神经瘤或许旺细胞瘤，是神经鞘最常见的肿瘤之一，通常出现在头部、颈部或上肢。根据文献报道，起源于腓总神经的下肢许旺细胞瘤很少见。我们报告了一例 32 岁男子的病例，他因左膝部肿块生长 6 个月而就诊。核磁共振检查发现了一个轮廓清晰的 9.6 厘米 × 7.8 厘米 × 6.5 厘米的多叶肿块，其密度不均，有坏死区，诊断为滑膜肉瘤。手术后，对肿瘤进行的最终组织病理学评估显示，肿瘤呈安东尼 A 型和 B 型，并伴有核淡化，这是分裂瘤的特征。术后，患者出现了神经系统并发症--左脚外翻功能受损。患者立即开始在康复科接受物理治疗。术后三周，患者的神经功能逐渐得到改善。迄今为止，完全切除肿瘤并进行显微镜分析和免疫组化染色仍是诊断和治疗周围神经裂孔瘤的金标准。此外，在手术过程中使用额外的神经监测工具有助于预防并发症。
{"title":"Giant Common Peroneal Nerve Schwannoma Mimicking Synovial Sarcoma: An Unusual Case Report","authors":"P. Tamulionis, E. Ostapenko, D. Šeinin, A. Kilius","doi":"10.4103/njcp.njcp_556_23","DOIUrl":"https://doi.org/10.4103/njcp.njcp_556_23","url":null,"abstract":"Schwannoma, also known as neurilemmoma or Schwann cell tumor, is one of the most common neoplasms of the nerve sheath which usually appears at the head, neck, or upper extremity. Schwannoma occurrence in the lower extremity originating from the common peroneal nerve is rarely reported according to literary findings. We report a case of a 32-year-old man who presented with a 6-month history of a growing lump in the left knee. MRT revealed a well-defined 9.6 cm × 7.8 cm × 6.5 cm multilobular mass of heterogeneous consistency with areas of necroses with a likely diagnosis of synovial sarcoma. After surgery, a final histopathological assessment of the tumor demonstrated Antoni A and B patterns with nuclear palisading, hallmarks of a schwannoma. Postoperatively the patient suffered a neurological complication–impaired dorsiflexion of the left foot. The patient started immediate physiotherapy in the Department of Rehabilitation. Three weeks after the operation, gradual improvement in neurological function was observed. To date, complete tumor excision combined with microscopic analysis and immunohistochemical staining remains the gold standard in diagnosing and treating a peripheral nerve schwannoma. Moreover, the use of additional nerve monitoring tools during surgery could help to prevent complications.","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/njcp.njcp_790_23
H. Webb, J. Toppi, J. Fairley, D. Phillips
Granulomatosis with polyangiitis (GPA) is rare but debilitating autoimmune disease and commonly presents with sinonasal as well as other head and neck symptoms. To summarize the ear, nose, and throat-specific symptomatology and management of GPA. We performed a literature review by using the PubMed search engine to provide a summary of recent and important literature that is pertinent to an otolaryngologist’s clinical practice. We provide a guide on the pathophysiology, epidemiology, clinical features, investigation, and management (operative and nonoperative) of this important disease. This review illustrates the important role that an otolaryngologist can play in the work up and symptom management of patients with GPA. Knowledge of the common presenting symptoms as well as more rare presentations of GPA is extremely important for otolaryngologists as prompt diagnosis and management is extremely important to avoid significant morbidity and mortality.
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