首页 > 最新文献

Nigerian Journal of Clinical Practice最新文献

英文 中文
Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy 牙髓再生疗法中应用的各种根管内药剂和支架组合可能引起的牙冠变色
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_126_24
NB Altun, A. Turkyilmaz
Regenerative endodontics involves the use of various root canal medicaments and scaffolds, which may cause crown discoloration. This study aimed to investigate the combined crown discoloration of scaffolds [platelet-rich fibrin (PRF) and blood clot] applied after administration of different medicaments [modified triple antibiotic paste including doxycycline (mTAPd), modified double antibiotic paste (mDAP), calcium hydroxide (CH), and propolis]. In total, 100 human mandibular premolar teeth were selected and prepared. The teeth were apically resected to simulate immature teeth. The positive and negative control groups (n = 10) consisted solely of blood-only and serum-only samples. The remaining 80 teeth were used for the experimental groups with four different medicaments. Three weeks later, either blood or PRF was applied as a scaffold after removing the medicaments (n = 10). Color changes were assessed before medication placement and at the end of the first, second, and third weeks, as well as on days 0, 1, 30, 60, and 90 after scaffold application. Analysis was carried out using repeated measures of variance, Friedman, one-way ANOVA, Kruskal-Wallis, the dependent paired t-test, and Wilcoxon test. Statistical significance was determined at P = 0.05. All groups including blood and the group including propolis and PRF combination, resulted in a significant increase in discoloration (P < 0.05) and discoloration exceeding clinically acceptable thresholds. CH and the modified versions of TAP (mTAPd) and DAP (mDAP) demonstrated an acceptable level of discoloration when used with a combination of PRF at day 90.
再生根管治疗涉及使用各种根管药物和支架,这可能会导致牙冠变色。 本研究旨在探讨在使用不同药物(改良三联抗生素糊剂,包括多西环素(mTAPd)、改良双联抗生素糊剂(mDAP)、氢氧化钙(CH)和蜂胶)后,支架(富血小板纤维蛋白(PRF)和血凝块)的联合牙冠变色情况。 共选择和制备了 100 颗人类下颌前磨牙。这些牙齿的根尖被切除,以模拟未成熟的牙齿。阳性对照组和阴性对照组(n = 10)仅由纯血液样本和纯血清样本组成。其余 80 颗牙齿用于实验组,使用四种不同的药物。三周后,移除药物后,将血液或 PRF 用作支架(n = 10)。在用药前、第一、第二和第三周结束时以及使用支架后的第 0、1、30、60 和 90 天评估颜色变化。分析方法包括重复方差分析、弗里德曼方差分析、单因素方差分析、Kruskal-Wallis 检验、因果配对 t 检验和 Wilcoxon 检验。 统计学意义以 P = 0.05 为标准。包括血液在内的所有组别以及包括蜂胶和 PRF 组合在内的组别都导致变色显著增加(P < 0.05),变色超过了临床可接受的阈值。 CH 和改良版 TAP(mTAPd)及 DAP(mDAP)在第 90 天与 PRF 组合使用时,变色程度可接受。
{"title":"Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy","authors":"NB Altun, A. Turkyilmaz","doi":"10.4103/njcp.njcp_126_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_126_24","url":null,"abstract":"\u0000 \u0000 Regenerative endodontics involves the use of various root canal medicaments and scaffolds, which may cause crown discoloration.\u0000 \u0000 \u0000 \u0000 This study aimed to investigate the combined crown discoloration of scaffolds [platelet-rich fibrin (PRF) and blood clot] applied after administration of different medicaments [modified triple antibiotic paste including doxycycline (mTAPd), modified double antibiotic paste (mDAP), calcium hydroxide (CH), and propolis].\u0000 \u0000 \u0000 \u0000 In total, 100 human mandibular premolar teeth were selected and prepared. The teeth were apically resected to simulate immature teeth. The positive and negative control groups (n = 10) consisted solely of blood-only and serum-only samples. The remaining 80 teeth were used for the experimental groups with four different medicaments. Three weeks later, either blood or PRF was applied as a scaffold after removing the medicaments (n = 10). Color changes were assessed before medication placement and at the end of the first, second, and third weeks, as well as on days 0, 1, 30, 60, and 90 after scaffold application. Analysis was carried out using repeated measures of variance, Friedman, one-way ANOVA, Kruskal-Wallis, the dependent paired t-test, and Wilcoxon test.\u0000 \u0000 \u0000 \u0000 Statistical significance was determined at P = 0.05. All groups including blood and the group including propolis and PRF combination, resulted in a significant increase in discoloration (P < 0.05) and discoloration exceeding clinically acceptable thresholds.\u0000 \u0000 \u0000 \u0000 CH and the modified versions of TAP (mTAPd) and DAP (mDAP) demonstrated an acceptable level of discoloration when used with a combination of PRF at day 90.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Pattern of Tooth Impaction: A Radiographic Study in a Trinidadian Population 牙齿嵌塞的发生率和模式:特立尼达人口的放射学研究
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_779_23
CN Naraynsingh, K. Henry, R. Hunte, N. Ramlogan, A. Bissoon
The aim of this retrospective study was to determine the prevalence and patterns of impacted third molars in a Trinidadian population. A total of 1500 orthopantomograms (OPG) taken at the School of Dentistry, University of the West Indies, from 2008 to 2019 in patients between 15 and 67 years old were evaluated. From the data collected, the prevalence of third molar impaction, the parameters of gender, angulation, level of impaction, and associated pathologies were evaluated. Other types of impacted teeth were also recorded. Of the 1500 OPG viewed, 408 (27.2%) of the study sample presented with at least one impacted third molar. 161 (39.5%) were males and 247 (60.5%) were females, with a male-to-female ratio of 1:1.5. There was a greater incidence of mandibular third molars versus maxillary third molars, which had a frequency of 77.9% and 22.1%, respectively. The most common type of impaction (Winter’s classification) was horizontal in the mandible and distoangular in the maxilla. The most common level of impaction in the mandible (Pell and Gregory classification) was level 1A. The total number of impacted teeth was 775, and of these, 75 (9.7%) showed other impacted teeth besides the third molars. Canines and second premolars were the most prevalent with 7.6% and 1.5%, respectively. Caries on the second molar (49.3%) and third molars (40%) were the most frequently associated pathologies identified. The prevalence of impacted wisdom teeth in this study was 27%. These results raise awareness and provide insight among dental professionals in Trinidad as to the prevalence of impacted third molars, their patterns, as well as commonly associated pathologies, and the need for screening within the population.
这项回顾性研究旨在确定第三磨牙撞击在特立尼达人口中的发生率和模式。 研究评估了西印度群岛大学牙科学院在 2008 年至 2019 年期间为 15 至 67 岁的患者拍摄的 1500 张正畸照片(OPG)。根据收集到的数据,对第三磨牙阻生的发生率、性别参数、角度、阻生程度以及相关病症进行了评估。此外,还记录了其他类型的阻生牙。 在观察的 1500 个 OPG 患者中,408 人(27.2%)至少有一颗第三磨牙阻生。其中男性 161 人(39.5%),女性 247 人(60.5%),男女比例为 1:1.5。下颌第三磨牙的发病率高于上颌第三磨牙,分别为 77.9% 和 22.1%。最常见的阻塞类型(温特分类法)是下颌的水平阻塞和上颌的二方阻塞。下颌最常见的阻生水平(佩尔和格雷戈里分类)是1A水平。受影响的牙齿总数为 775 颗,其中 75 颗(9.7%)除了第三磨牙外还有其他受影响的牙齿。犬齿和第二前臼齿的发病率最高,分别为 7.6% 和 1.5%。第二磨牙(49.3%)和第三磨牙(40%)龋坏是最常见的相关病变。 在这项研究中,智齿撞击的发病率为 27%。这些结果提高了特立尼达牙科专业人员对影响性第三磨牙的发病率、发病模式、常见相关病症以及在人群中进行筛查的必要性的认识和了解。
{"title":"Prevalence and Pattern of Tooth Impaction: A Radiographic Study in a Trinidadian Population","authors":"CN Naraynsingh, K. Henry, R. Hunte, N. Ramlogan, A. Bissoon","doi":"10.4103/njcp.njcp_779_23","DOIUrl":"https://doi.org/10.4103/njcp.njcp_779_23","url":null,"abstract":"\u0000 \u0000 The aim of this retrospective study was to determine the prevalence and patterns of impacted third molars in a Trinidadian population.\u0000 \u0000 \u0000 \u0000 A total of 1500 orthopantomograms (OPG) taken at the School of Dentistry, University of the West Indies, from 2008 to 2019 in patients between 15 and 67 years old were evaluated. From the data collected, the prevalence of third molar impaction, the parameters of gender, angulation, level of impaction, and associated pathologies were evaluated. Other types of impacted teeth were also recorded.\u0000 \u0000 \u0000 \u0000 Of the 1500 OPG viewed, 408 (27.2%) of the study sample presented with at least one impacted third molar. 161 (39.5%) were males and 247 (60.5%) were females, with a male-to-female ratio of 1:1.5. There was a greater incidence of mandibular third molars versus maxillary third molars, which had a frequency of 77.9% and 22.1%, respectively. The most common type of impaction (Winter’s classification) was horizontal in the mandible and distoangular in the maxilla. The most common level of impaction in the mandible (Pell and Gregory classification) was level 1A. The total number of impacted teeth was 775, and of these, 75 (9.7%) showed other impacted teeth besides the third molars. Canines and second premolars were the most prevalent with 7.6% and 1.5%, respectively. Caries on the second molar (49.3%) and third molars (40%) were the most frequently associated pathologies identified.\u0000 \u0000 \u0000 \u0000 The prevalence of impacted wisdom teeth in this study was 27%. These results raise awareness and provide insight among dental professionals in Trinidad as to the prevalence of impacted third molars, their patterns, as well as commonly associated pathologies, and the need for screening within the population.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Sexual Quality of Life on Self-Management Perceptions of Women with Type 2 Diabetes 性生活质量对 2 型糖尿病女性患者自我管理观念的影响
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_88_24
N. Eroğlu
The quality of sexual life of women with type 2 diabetes has an impact on their self-management perceptions. To evaluate the effect of quality of sexual life on self-care perceptions of women with type 2 diabetes mellitus (DM). It was an online descriptive study of 127 women with type 2 DM. The questionnaire consisted of a patient information form, sexual quality of life scale-female, and diabetes self-management perception scale. There was a significant relationship between diabetes self-management perception and sexual quality of life (P = 0.000). The individuals’ diabetes self-management perception scores differed significantly according to their age (F = 3.12; P = 0.047), and the sexual quality of life scores differed significantly according to their treatment type (F = 4.01; P = 0.020). There is a relationship between quality of sexual life and self-management perceptions of women with type 2 DM. As the quality of sexual life increases, diabetes self-management perceptions increase. Age affects diabetes self-management perception, and the type of treatment used by individuals also affects their quality of sexual life.
2 型糖尿病女性患者的性生活质量对其自我管理观念有影响。 目的:评估性生活质量对 2 型糖尿病(DM)女性患者自我管理观念的影响。 这是一项针对 127 名 2 型糖尿病女性患者的在线描述性研究。问卷包括患者信息表、女性性生活质量量表和糖尿病自我管理感知量表。 糖尿病自我管理感知与性生活质量之间存在明显关系(P = 0.000)。个人的糖尿病自我管理感知得分因年龄不同而有显著差异(F = 3.12;P = 0.047),性生活质量得分因治疗类型不同而有显著差异(F = 4.01;P = 0.020)。 2 型糖尿病妇女的性生活质量与自我管理观念之间存在关系。随着性生活质量的提高,糖尿病自我管理观念也会提高。年龄会影响对糖尿病自我管理的认知,个人使用的治疗类型也会影响其性生活质量。
{"title":"Effect of Sexual Quality of Life on Self-Management Perceptions of Women with Type 2 Diabetes","authors":"N. Eroğlu","doi":"10.4103/njcp.njcp_88_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_88_24","url":null,"abstract":"\u0000 \u0000 The quality of sexual life of women with type 2 diabetes has an impact on their self-management perceptions.\u0000 \u0000 \u0000 \u0000 To evaluate the effect of quality of sexual life on self-care perceptions of women with type 2 diabetes mellitus (DM).\u0000 \u0000 \u0000 \u0000 It was an online descriptive study of 127 women with type 2 DM. The questionnaire consisted of a patient information form, sexual quality of life scale-female, and diabetes self-management perception scale.\u0000 \u0000 \u0000 \u0000 There was a significant relationship between diabetes self-management perception and sexual quality of life (P = 0.000). The individuals’ diabetes self-management perception scores differed significantly according to their age (F = 3.12; P = 0.047), and the sexual quality of life scores differed significantly according to their treatment type (F = 4.01; P = 0.020).\u0000 \u0000 \u0000 \u0000 There is a relationship between quality of sexual life and self-management perceptions of women with type 2 DM. As the quality of sexual life increases, diabetes self-management perceptions increase. Age affects diabetes self-management perception, and the type of treatment used by individuals also affects their quality of sexual life.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Importance of the Time Interval Between Preoperative 18F-FDG PET/CT Imaging and Neck Dissection for the Detection of Nodal Metastases in Patients with Head and Neck Squamous Cell Carcinoma 术前 18F-FDG PET/CT 成像与颈部切除术之间的时间间隔对检测头颈部鳞状细胞癌患者结节转移的重要性
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_38_24
E. Koroglu, S. Sirin, S. Isgoren
Detection of nodal metastasis is critical for the treatment and prognosis of head and neck cancer (HNC). Positron emission tomography/computed tomography (PET/CT) is increasingly being used to detect cervical lymph node involvement. The purposes of this study were to (1) investigate the diagnostic accuracy of PET/CT for the detection of neck metastasis in patients with HNC and (2) determine the effect of the time interval between surgery and PET/CT. Fifty patients with head and neck squamous cell carcinoma who underwent PET/CT before surgery were included in this study. Preoperative PET/CT images that determined lymph node metastasis were compared with the histopathological analysis of neck dissection samples. Neck dissections were divided into three groups according to the time interval between surgery and PET/CT (0–2 weeks, >2–4 weeks, and >4 weeks). The concordance between PET/CT and histopathology was measured using the neck sides at different time intervals. The specificity, sensitivity, accuracy, negative predictive value (NPV), and positive predictive value (PPV) of PET/CT in detecting metastatic lymph nodes in the neck were calculated. A total of 79 neck dissections were included in the study as 29 (58%) of the patients underwent bilateral neck dissection. The overall accuracy of PET/CT in detecting nodal metastasis was highest for the 0–2 weeks interval (95.6%). During this time interval, the sensitivity, specificity, NPV, and PPV of PET/CT were 100%, 90.9%, 100%, and 92.3%, respectively. Although PET/CT is an important and reliable diagnostic method for detecting nodal metastases in patients with HNC, its reliability decreases as the time between surgeries increases. The optimal interval was 2 weeks; however, up to 4 weeks was acceptable.
结节转移的检测对于头颈癌(HNC)的治疗和预后至关重要。正电子发射断层扫描/计算机断层扫描(PET/CT)越来越多地用于检测颈淋巴结受累情况。 本研究的目的是:(1) 探讨 PET/CT 检测 HNC 患者颈部转移的诊断准确性;(2) 确定手术与 PET/CT 之间时间间隔的影响。 本研究纳入了 50 名在手术前接受 PET/CT 检查的头颈部鳞状细胞癌患者。将确定淋巴结转移的术前 PET/CT 图像与颈部切除样本的组织病理学分析进行比较。根据手术与 PET/CT 的时间间隔(0-2 周、>2-4 周和>4 周),将颈部切除术分为三组。使用不同时间间隔的颈部两侧样本测量 PET/CT 与组织病理学的一致性。计算了 PET/CT 检测颈部转移淋巴结的特异性、敏感性、准确性、阴性预测值(NPV)和阳性预测值(PPV)。 研究共纳入了 79 例颈部切除术,其中 29 例(58%)患者接受了双侧颈部切除术。PET/CT 检测结节转移的总体准确率在 0-2 周间隔内最高(95.6%)。在这个时间间隔内,PET/CT 的敏感性、特异性、NPV 和 PPV 分别为 100%、90.9%、100% 和 92.3%。 尽管 PET/CT 是检测 HNC 患者结节转移的一种重要而可靠的诊断方法,但其可靠性会随着手术间隔时间的延长而降低。最佳间隔时间为 2 周,但最长 4 周也是可以接受的。
{"title":"The Importance of the Time Interval Between Preoperative 18F-FDG PET/CT Imaging and Neck Dissection for the Detection of Nodal Metastases in Patients with Head and Neck Squamous Cell Carcinoma","authors":"E. Koroglu, S. Sirin, S. Isgoren","doi":"10.4103/njcp.njcp_38_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_38_24","url":null,"abstract":"\u0000 \u0000 Detection of nodal metastasis is critical for the treatment and prognosis of head and neck cancer (HNC). Positron emission tomography/computed tomography (PET/CT) is increasingly being used to detect cervical lymph node involvement.\u0000 \u0000 \u0000 \u0000 The purposes of this study were to (1) investigate the diagnostic accuracy of PET/CT for the detection of neck metastasis in patients with HNC and (2) determine the effect of the time interval between surgery and PET/CT.\u0000 \u0000 \u0000 \u0000 Fifty patients with head and neck squamous cell carcinoma who underwent PET/CT before surgery were included in this study. Preoperative PET/CT images that determined lymph node metastasis were compared with the histopathological analysis of neck dissection samples. Neck dissections were divided into three groups according to the time interval between surgery and PET/CT (0–2 weeks, >2–4 weeks, and >4 weeks). The concordance between PET/CT and histopathology was measured using the neck sides at different time intervals. The specificity, sensitivity, accuracy, negative predictive value (NPV), and positive predictive value (PPV) of PET/CT in detecting metastatic lymph nodes in the neck were calculated.\u0000 \u0000 \u0000 \u0000 A total of 79 neck dissections were included in the study as 29 (58%) of the patients underwent bilateral neck dissection. The overall accuracy of PET/CT in detecting nodal metastasis was highest for the 0–2 weeks interval (95.6%). During this time interval, the sensitivity, specificity, NPV, and PPV of PET/CT were 100%, 90.9%, 100%, and 92.3%, respectively.\u0000 \u0000 \u0000 \u0000 Although PET/CT is an important and reliable diagnostic method for detecting nodal metastases in patients with HNC, its reliability decreases as the time between surgeries increases. The optimal interval was 2 weeks; however, up to 4 weeks was acceptable.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Systematic Review of the Clinical Effectiveness of Cochlear Implant Surgery in Pediatric and Adult Patients 人工耳蜗手术对儿童和成人患者临床疗效的系统回顾
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_1470_21
A. Musleh
Hearing loss, also termed as hearing impairment, is an ailment where hearing is impaired partially or fully. About one in eight people suffer from hearing loss worldwide. The main aim of this current systematic review was to analyze the clinical effectiveness of cochlear implant (CI) surgery in pediatric and adult patients. The current study was carried out as a systematic review, following the PRISMA guidelines. We systematically searched PubMed, MEDLINE, EMBASE, and Google Scholar databases to identify eligible articles on the clinical effectiveness of CI surgery with the appropriate key terms (MeSH). This review included 73 studies which met the inclusion criteria. The studies included in unilateral CI in adults showed significant improvement in terms of perceptive abilities. Bilateral CI studies with respect to unilateral CI provide benefits in hearing in quiet conditions and sound localization. In the performance of post CI outcomes in patients, the age is not a determinant factor. CI is an effective aid in communication and speech perception for a majority of people with mild to severe hearing loss. Further studies are needed with large databases, patient registries for long term follow up details, higher quality reporting, and longer duration to develop stronger evidence.
听力损失又称听力障碍,是指听力部分或全部受损的疾病。全世界约有八分之一的人患有听力损失。本次系统综述的主要目的是分析人工耳蜗(CI)手术对儿童和成人患者的临床疗效。本研究是按照 PRISMA 指南进行的系统性综述。我们系统地检索了 PubMed、MEDLINE、EMBASE 和 Google Scholar 数据库,以适当的关键术语(MeSH)确定符合条件的有关 CI 手术临床效果的文章。本综述共纳入了 73 项符合纳入标准的研究。纳入的成人单侧 CI 研究显示,患者的感知能力有显著改善。与单侧 CI 相比,双侧 CI 研究在安静环境下的听力和声音定位方面都有所提高。在对患者进行 CI 后的效果评估时,年龄并不是决定性因素。对于大多数轻度至重度听力损失患者来说,CI 是一种有效的交流和言语感知辅助工具。要想获得更有力的证据,还需要进行更多的研究,如建立大型数据库、对患者进行长期随访登记、提供更高质量的报告、延长随访时间等。
{"title":"A Systematic Review of the Clinical Effectiveness of Cochlear Implant Surgery in Pediatric and Adult Patients","authors":"A. Musleh","doi":"10.4103/njcp.njcp_1470_21","DOIUrl":"https://doi.org/10.4103/njcp.njcp_1470_21","url":null,"abstract":"Hearing loss, also termed as hearing impairment, is an ailment where hearing is impaired partially or fully. About one in eight people suffer from hearing loss worldwide. The main aim of this current systematic review was to analyze the clinical effectiveness of cochlear implant (CI) surgery in pediatric and adult patients. The current study was carried out as a systematic review, following the PRISMA guidelines. We systematically searched PubMed, MEDLINE, EMBASE, and Google Scholar databases to identify eligible articles on the clinical effectiveness of CI surgery with the appropriate key terms (MeSH). This review included 73 studies which met the inclusion criteria. The studies included in unilateral CI in adults showed significant improvement in terms of perceptive abilities. Bilateral CI studies with respect to unilateral CI provide benefits in hearing in quiet conditions and sound localization. In the performance of post CI outcomes in patients, the age is not a determinant factor. CI is an effective aid in communication and speech perception for a majority of people with mild to severe hearing loss. Further studies are needed with large databases, patient registries for long term follow up details, higher quality reporting, and longer duration to develop stronger evidence.","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors of Cardiac Complications in Pregnant Women with Hypertrophic Cardiomyopathy 肥厚型心肌病孕妇心脏并发症的风险因素
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_62_24
TT Huang, SH Feng, JH Lin
Hypertrophic cardiomyopathy (HCM) is a common inherited genetic cardiac disease during pregnancy. Studies of risk factors are of great significance for maternal and fetal outcomes. The aim of the study was to identify predictive risk factors for cardiac complications in pregnant women with HCM. One hundred patients with HCM who delivered at the Shanghai obstetrical cardiology intensive care center between January 2000 and December 2022 were retrospectively reviewed. A logistic regression model was used to identify independent risk factors for cardiac complications. Twenty-one cases were obstructive HCM (21%), 16 with cardiac function grade I and 5 with grade II; 79 cases were non-obstructive HCM (79%), 67 with cardiac function grade I, 11 with grade II, and 1 with grade III. Ninety-one cases had abnormal electrocardiogram (ECG) (91%), mainly with ST-T changes (77%). The average interventricular septum was 19.39 ± 6.13 mm by echocardiography (21.75 ± 5.86 mm for obstructive HCM and 18.73 ± 6.08 mm for non-obstructive HCM). The main cardiac complications were maternal death (n = 2, 2%), heart failure (n = 7, 7%), and sustained ventricular tachyarrhythmia (n = 1, 1%). Cardiac complications occur commonly during the third trimester and postpartum period. Three independent risk factors to predict cardiac complications in pregnant women with HCM were obstructive HCM (P = 0.036), New York Heart Association (NYHA) class ≥II (P = 0.022), and previous history of syncope (P = 0.037). HCM increases the risk of maternal death, heart failure, and malignant arrhythmia. More attention should be given to risk assessment and pregnancy management. Early detection of risk factors can reduce the incidence of maternal mortality and cardiac complications.
肥厚型心肌病(HCM)是妊娠期常见的遗传性心脏病。对风险因素的研究对孕产妇和胎儿的预后具有重要意义。 本研究旨在确定 HCM 孕妇心脏并发症的预测风险因素。 研究回顾性分析了 2000 年 1 月至 2022 年 12 月期间在上海产科心脏病重症监护中心分娩的 100 例 HCM 患者。采用逻辑回归模型确定心脏并发症的独立风险因素。 21例为梗阻性HCM(21%),16例为心功能Ⅰ级,5例为Ⅱ级;79例为非梗阻性HCM(79%),67例为心功能Ⅰ级,11例为Ⅱ级,1例为Ⅲ级。91例患者心电图(ECG)异常(91%),主要为ST-T改变(77%)。超声心动图显示,平均室间隔为(19.39 ± 6.13)毫米(阻塞性 HCM 为(21.75 ± 5.86)毫米,非阻塞性 HCM 为(18.73 ± 6.08)毫米)。主要的心脏并发症是产妇死亡(2 例,占 2%)、心力衰竭(7 例,占 7%)和持续性室性心动过速(1 例,占 1%)。心脏并发症通常发生在妊娠三个月和产后。预测 HCM 孕妇心脏并发症的三个独立风险因素是阻塞性 HCM(P = 0.036)、纽约心脏协会(NYHA)分级≥II(P = 0.022)和既往晕厥史(P = 0.037)。 HCM 会增加产妇死亡、心力衰竭和恶性心律失常的风险。应更加重视风险评估和孕期管理。及早发现风险因素可降低孕产妇死亡率和心脏并发症的发生率。
{"title":"Risk Factors of Cardiac Complications in Pregnant Women with Hypertrophic Cardiomyopathy","authors":"TT Huang, SH Feng, JH Lin","doi":"10.4103/njcp.njcp_62_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_62_24","url":null,"abstract":"\u0000 \u0000 Hypertrophic cardiomyopathy (HCM) is a common inherited genetic cardiac disease during pregnancy. Studies of risk factors are of great significance for maternal and fetal outcomes.\u0000 \u0000 \u0000 \u0000 The aim of the study was to identify predictive risk factors for cardiac complications in pregnant women with HCM.\u0000 \u0000 \u0000 \u0000 One hundred patients with HCM who delivered at the Shanghai obstetrical cardiology intensive care center between January 2000 and December 2022 were retrospectively reviewed. A logistic regression model was used to identify independent risk factors for cardiac complications.\u0000 \u0000 \u0000 \u0000 Twenty-one cases were obstructive HCM (21%), 16 with cardiac function grade I and 5 with grade II; 79 cases were non-obstructive HCM (79%), 67 with cardiac function grade I, 11 with grade II, and 1 with grade III. Ninety-one cases had abnormal electrocardiogram (ECG) (91%), mainly with ST-T changes (77%). The average interventricular septum was 19.39 ± 6.13 mm by echocardiography (21.75 ± 5.86 mm for obstructive HCM and 18.73 ± 6.08 mm for non-obstructive HCM). The main cardiac complications were maternal death (n = 2, 2%), heart failure (n = 7, 7%), and sustained ventricular tachyarrhythmia (n = 1, 1%). Cardiac complications occur commonly during the third trimester and postpartum period. Three independent risk factors to predict cardiac complications in pregnant women with HCM were obstructive HCM (P = 0.036), New York Heart Association (NYHA) class ≥II (P = 0.022), and previous history of syncope (P = 0.037).\u0000 \u0000 \u0000 \u0000 HCM increases the risk of maternal death, heart failure, and malignant arrhythmia. More attention should be given to risk assessment and pregnancy management. Early detection of risk factors can reduce the incidence of maternal mortality and cardiac complications.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fucoidan Inhibits Prostate Cancer Growth Through Modulation of Different Cell Deaths 褐藻糖胶通过调节不同细胞的死亡抑制前列腺癌的生长
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-01 DOI: 10.4103/njcp.njcp_512_23
M. Tutuncu, G. Sanlav, S. Aktaş, O. Yilmaz, ZS Altun
Docetaxel (DOC) is the main chemotherapeutic agent for the treatment of advanced metastatic prostate cancer. Docetaxel shows anticancer effects by preventing the depolymerization of microtubules in the cell, therefore preventing cell division. However, the low survival effect of docetaxel has prompted researchers to search for novel therapeutic agents. Fucoidan (FUC) is a sulfated polysaccharide derived from brown algae. It has many bioactivities which makes fucoidan a promising anticancer agent. In this study, the potential anti-tumorigenic and preventive effects of fucoidan with or without docetaxel in prostate cancer were investigated by analyzing different cell death modalities. The in-vivo six groups (n = 8) were conducted; preventive (Pt), docetaxel treated after preventive (Pt-D), control, fucoidan (FUC), docetaxel (DOC), and FUC and DOC (FUC+DOC) combination. Apoptotic, necroptotic, and autophagic cell death-related protein expressions were assessed in tumor tissues by using immunohistochemical staining. Oxidative stress-related lipid peroxidation, glutathione peroxidase, and glutathione levels were also determined in tumor tissues. Although apoptotic, necroptotic, and autophagic cell deaths were significantly induced in agent-treated groups compared to the control. Apoptotic cell death was more significantly induced in FUC and FUC+DOC-treated groups. Necroptotic cell death was increased considerably by inducing MLKL protein expression in all treatment groups. In the FUC, Pt, and DOC groups, LC3A/B expressions were significantly increased. DOC, FUC+DOC, and Pt-D treatments caused a significant increase in Beclin-1 expression. Oxidative stress-related MDA, GPX, and GSH levels significantly decreased with FUC treatment. The anti-tumorigenic effects of FUC and DOC were also demonstrated through tumor size reduction. According to the findings of this study, FUC inhibited tumor growth temporally and dimensionally, especially in preventive applications. FUC and FUC+DOC combinations in both treatment groups showed anti-tumorigenic effects. The results of this study suggest that fucoidan is a promising anticancer agent against prostate cancer. FUC can be considered as a preventive or treatment agent in prostate cancer therapy with DOC. Further studies are needed to fully elucidate the mechanism of action of fucoidan in metastatic prostate cancer.
多西他赛(DOC)是治疗晚期转移性前列腺癌的主要化疗药物。多西他赛通过阻止细胞内微管的解聚,从而阻止细胞分裂,达到抗癌效果。然而,多西他赛的存活率较低,这促使研究人员寻找新型治疗药物。褐藻糖胶(FUC)是从褐藻中提取的硫酸化多糖。褐藻糖胶具有多种生物活性,是一种很有前景的抗癌药物。本研究通过分析不同的细胞死亡模式,研究了褐藻糖胶与多西他赛或不与多西他赛联合使用对前列腺癌的潜在抗肿瘤和预防作用。 研究在体内进行了六组(n = 8)试验:预防组(Pt)、预防后多西他赛组(Pt-D)、对照组、褐藻糖胶组(FUC)、多西他赛组(DOC)、FUC 和 DOC 组(FUC+DOC)。免疫组化染色法评估了肿瘤组织中与细胞凋亡、坏死和自噬相关的蛋白质表达。此外,还测定了肿瘤组织中与氧化应激相关的脂质过氧化反应、谷胱甘肽过氧化物酶和谷胱甘肽水平。 与对照组相比,药剂处理组显著诱导细胞凋亡、坏死和自噬。FUC和FUC+DOC处理组诱导的细胞凋亡更为明显。在所有处理组中,通过诱导 MLKL 蛋白的表达,坏死细胞的死亡大大增加。在 FUC、Pt 和 DOC 组中,LC3A/B 的表达明显增加。DOC、FUC+DOC和Pt-D处理导致Beclin-1表达量明显增加。氧化应激相关的MDA、GPX和GSH水平在FUC处理后明显下降。FUC 和 DOC 的抗肿瘤作用还体现在肿瘤体积的缩小上。 根据这项研究的结果,FUC 可在时间上和尺寸上抑制肿瘤生长,尤其是在预防性应用中。两个治疗组中的 FUC 和 FUC+DOC 组合均显示出抗肿瘤作用。研究结果表明,褐藻糖胶是一种很有前景的前列腺癌抗癌剂。褐藻糖胶可作为一种预防或治疗前列腺癌的药物。要全面阐明褐藻糖胶对转移性前列腺癌的作用机制,还需要进一步的研究。
{"title":"Fucoidan Inhibits Prostate Cancer Growth Through Modulation of Different Cell Deaths","authors":"M. Tutuncu, G. Sanlav, S. Aktaş, O. Yilmaz, ZS Altun","doi":"10.4103/njcp.njcp_512_23","DOIUrl":"https://doi.org/10.4103/njcp.njcp_512_23","url":null,"abstract":"\u0000 \u0000 Docetaxel (DOC) is the main chemotherapeutic agent for the treatment of advanced metastatic prostate cancer. Docetaxel shows anticancer effects by preventing the depolymerization of microtubules in the cell, therefore preventing cell division. However, the low survival effect of docetaxel has prompted researchers to search for novel therapeutic agents. Fucoidan (FUC) is a sulfated polysaccharide derived from brown algae. It has many bioactivities which makes fucoidan a promising anticancer agent. In this study, the potential anti-tumorigenic and preventive effects of fucoidan with or without docetaxel in prostate cancer were investigated by analyzing different cell death modalities.\u0000 \u0000 \u0000 \u0000 The in-vivo six groups (n = 8) were conducted; preventive (Pt), docetaxel treated after preventive (Pt-D), control, fucoidan (FUC), docetaxel (DOC), and FUC and DOC (FUC+DOC) combination. Apoptotic, necroptotic, and autophagic cell death-related protein expressions were assessed in tumor tissues by using immunohistochemical staining. Oxidative stress-related lipid peroxidation, glutathione peroxidase, and glutathione levels were also determined in tumor tissues.\u0000 \u0000 \u0000 \u0000 Although apoptotic, necroptotic, and autophagic cell deaths were significantly induced in agent-treated groups compared to the control. Apoptotic cell death was more significantly induced in FUC and FUC+DOC-treated groups. Necroptotic cell death was increased considerably by inducing MLKL protein expression in all treatment groups. In the FUC, Pt, and DOC groups, LC3A/B expressions were significantly increased. DOC, FUC+DOC, and Pt-D treatments caused a significant increase in Beclin-1 expression. Oxidative stress-related MDA, GPX, and GSH levels significantly decreased with FUC treatment. The anti-tumorigenic effects of FUC and DOC were also demonstrated through tumor size reduction.\u0000 \u0000 \u0000 \u0000 According to the findings of this study, FUC inhibited tumor growth temporally and dimensionally, especially in preventive applications. FUC and FUC+DOC combinations in both treatment groups showed anti-tumorigenic effects. The results of this study suggest that fucoidan is a promising anticancer agent against prostate cancer. FUC can be considered as a preventive or treatment agent in prostate cancer therapy with DOC. Further studies are needed to fully elucidate the mechanism of action of fucoidan in metastatic prostate cancer.\u0000","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Evaluation of the Effects of Local Anesthesia Before Tooth Extraction Procedures under General Anesthesia on Physiologic Parameters and Postoperative Bleeding in Children. 回顾性评估全身麻醉下拔牙术前局部麻醉对儿童生理参数和术后出血的影响。
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2024-06-29 DOI: 10.4103/njcp.njcp_708_23
Y Turan, G B Senirkentli, N Cekmen, E Tirali, E Çakmak

Background: Studies have been conducted to evaluate changes in hemodynamics, postoperative bleeding, and pain in pediatric dental patients receiving general anesthesia (GA). However, a limited number of studies have evaluated the effects of local anesthetics (LA) on tooth extraction procedures during GA. There is no consensus in the literature regarding LA application in the perioperative period for dental treatments performed within the scope of GA.

Aim: This study aimed to determine the retrospective physiologic effects of fluctuations in vital signs and postoperative bleeding in children who did or did not receive LA for tooth extraction under GA.

Methods: A retrospective evaluation of 77 patients aged 5.16 ± 1.85 years who had the extraction of primary posterior teeth with or without LA under GA were reviewed in the post-anaesthesia care unit (PACU) for postoperative bleeding and the effects of intraoperative LA on fluctuations in postoperative parameters such as mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation (SpO2), respiratory rate (RR), and the end-tidal carbon dioxide (EtCO2). These were compiled from the patient records of the procedures.

Results: Significant differences between the baseline and peak MAP (P < 0.001), HR (P = 0.011), and EtCO2 (P = 0.002) were noted in children without LA compared to those who had LA. In addition, substantial variations were observed between the baseline and peak values for MAP (P < 0.001) and HR (P = 0.037) in children who had tooth extraction in the mandibular region. Statistically significant differences were noted between the baseline and peak values for patients who did not receive LA before the extraction of the first primary molar in terms of MAP (P < 0.02) and EtCO2 (P = 0.032). Similarly, significant differences in MAP (P < 0.02) and EtCO2 (P = 0.034) were noted in the extraction of the second primary molar. In addition, there was a significant difference in bleeding based on the number of tooth extractions in those who did not receive LA (P = 0.020).

Conclusion: This study showed that in children who underwent tooth extraction under GA, additional LA application minimized changes in HR, MAP, and EtCO2, whereas a lack of LA application produced significant fluctuations from baseline to peak values of HR, MAP, and EtCO2. In addition, LA application reduced postoperative bleeding.

背景:已有研究对接受全身麻醉(GA)的儿童牙科患者的血液动力学、术后出血和疼痛的变化进行了评估。然而,对局部麻醉剂(LA)在全身麻醉期间对拔牙程序的影响进行评估的研究数量有限。目的:本研究旨在确定在全身麻醉下拔牙时接受或未接受局部麻醉剂(LA)的儿童的生命体征波动和术后出血的回顾性生理影响:方法:在麻醉后护理病房(PACU)对77例年龄为(5.16±1.85)岁、在GA下接受或未接受LA拔除初级后牙的患者进行回顾性评估,以了解术后出血情况以及术中LA对平均动脉压(MAP)、心率(HR)、外周血氧饱和度(SpO2)、呼吸频率(RR)和潮气末二氧化碳(EtCO2)等术后参数波动的影响。这些数据均来自患者的手术记录:结果:与患有 LA 的儿童相比,未患 LA 的儿童的基线和峰值 MAP(P < 0.001)、HR(P = 0.011)和 EtCO2(P = 0.002)之间存在显著差异。此外,在下颌区域拔牙的儿童中,MAP(P < 0.001)和 HR(P = 0.037)的基线值和峰值之间存在显著差异。在拔除第一磨牙前未接受 LA 治疗的患者,其 MAP(P < 0.02)和 EtCO2(P = 0.032)的基线值和峰值之间存在统计学意义上的显著差异。同样,在拔除第二颗原臼齿时,MAP(P < 0.02)和 EtCO2(P = 0.034)也有明显差异。此外,根据拔牙次数,未接受 LA 治疗的儿童的出血量也存在明显差异(P = 0.020):本研究表明,在全麻下拔牙的儿童中,额外应用 LA 可最大限度地减少 HR、MAP 和 EtCO2 的变化,而不应用 LA 则会产生 HR、MAP 和 EtCO2 从基线到峰值的显著波动。此外,应用 LA 还能减少术后出血。
{"title":"Retrospective Evaluation of the Effects of Local Anesthesia Before Tooth Extraction Procedures under General Anesthesia on Physiologic Parameters and Postoperative Bleeding in Children.","authors":"Y Turan, G B Senirkentli, N Cekmen, E Tirali, E Çakmak","doi":"10.4103/njcp.njcp_708_23","DOIUrl":"https://doi.org/10.4103/njcp.njcp_708_23","url":null,"abstract":"<p><strong>Background: </strong>Studies have been conducted to evaluate changes in hemodynamics, postoperative bleeding, and pain in pediatric dental patients receiving general anesthesia (GA). However, a limited number of studies have evaluated the effects of local anesthetics (LA) on tooth extraction procedures during GA. There is no consensus in the literature regarding LA application in the perioperative period for dental treatments performed within the scope of GA.</p><p><strong>Aim: </strong>This study aimed to determine the retrospective physiologic effects of fluctuations in vital signs and postoperative bleeding in children who did or did not receive LA for tooth extraction under GA.</p><p><strong>Methods: </strong>A retrospective evaluation of 77 patients aged 5.16 ± 1.85 years who had the extraction of primary posterior teeth with or without LA under GA were reviewed in the post-anaesthesia care unit (PACU) for postoperative bleeding and the effects of intraoperative LA on fluctuations in postoperative parameters such as mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation (SpO2), respiratory rate (RR), and the end-tidal carbon dioxide (EtCO2). These were compiled from the patient records of the procedures.</p><p><strong>Results: </strong>Significant differences between the baseline and peak MAP (P < 0.001), HR (P = 0.011), and EtCO2 (P = 0.002) were noted in children without LA compared to those who had LA. In addition, substantial variations were observed between the baseline and peak values for MAP (P < 0.001) and HR (P = 0.037) in children who had tooth extraction in the mandibular region. Statistically significant differences were noted between the baseline and peak values for patients who did not receive LA before the extraction of the first primary molar in terms of MAP (P < 0.02) and EtCO2 (P = 0.032). Similarly, significant differences in MAP (P < 0.02) and EtCO2 (P = 0.034) were noted in the extraction of the second primary molar. In addition, there was a significant difference in bleeding based on the number of tooth extractions in those who did not receive LA (P = 0.020).</p><p><strong>Conclusion: </strong>This study showed that in children who underwent tooth extraction under GA, additional LA application minimized changes in HR, MAP, and EtCO2, whereas a lack of LA application produced significant fluctuations from baseline to peak values of HR, MAP, and EtCO2. In addition, LA application reduced postoperative bleeding.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Case for Re-Classification of Solid and Ameloblastoma from Benign to Borderline Tumor. 将实体瘤和绒母细胞瘤从良性肿瘤重新分类为边缘性肿瘤的案例。
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2024-06-29 DOI: 10.4103/njcp.njcp_63_24
M C Nwoga
{"title":"The Case for Re-Classification of Solid and Ameloblastoma from Benign to Borderline Tumor.","authors":"M C Nwoga","doi":"10.4103/njcp.njcp_63_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_63_24","url":null,"abstract":"","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating Body Image and Self-Esteem in Kidney Transplant Patients: A Qualitative Study. 调查肾移植患者的身体形象和自尊:定性研究。
IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2024-06-29 DOI: 10.4103/njcp.njcp_138_24
N Akıncı, Y Varışoğlu

Background: Kidney transplantation is one of the life-saving therapies for patients with end-stage renal disease, which affects a person's psychological, social, and physical well-being. How transplanted patients perceive their illness and their body can affect their physical and psychological recovery.

Aim: This qualitative study was designed to evaluate self-esteem and body image in kidney transplant patients.

Methods: The study involved 16 female renal transplanted patients. Data were collected using a two-part interview form developed by the investigators in accordance with the literature. We used Lundman's method to transcribe the interviews and coded the data from the interviews. The results of the study were discussed using the themes. The first three interviews were entered into MAXQDA, and then, additional interviews were analyzed.

Results: Six main themes and 15 subthemes were generated based on the thematic analysis of the interviews with participants about body image and self-esteem. Themes included body acceptance, changes in body image, deterioration of social relationships, changes in self-esteem, spousal concerns, and organ perceptions. This study collected detailed data on body image, self-esteem, social relationships, and spouse/partner relationships after kidney transplantation.

Conclusion: The change in participants' body image and self-esteem after kidney transplantation caused having negative feelings regarding sexual life, relationships, and social life and feeling unfamiliar with the transplanted organ.

背景:肾移植是终末期肾病患者的救命疗法之一,它会影响患者的心理、社交和身体健康。肾移植患者如何看待自己的疾病和身体会影响他们的身体和心理康复:研究涉及 16 名女性肾移植患者。数据收集采用了研究人员根据文献制定的由两部分组成的访谈表。我们采用伦德曼法对访谈进行了转录,并对访谈数据进行了编码。我们使用主题对研究结果进行了讨论。我们将前三个访谈输入 MAXQDA,然后对其他访谈进行了分析:根据对参与者关于身体形象和自尊的访谈进行的主题分析,得出了 6 个主主题和 15 个次主题。主题包括对身体的接受、身体形象的改变、社会关系的恶化、自尊的改变、配偶的担忧以及对器官的看法。本研究收集了有关肾移植后身体形象、自尊、社会关系和配偶/伴侣关系的详细数据:结论:肾移植后,参与者的身体形象和自尊发生了变化,导致他们对性生活、人际关系和社交生活产生负面情绪,并对移植器官感到陌生。
{"title":"Investigating Body Image and Self-Esteem in Kidney Transplant Patients: A Qualitative Study.","authors":"N Akıncı, Y Varışoğlu","doi":"10.4103/njcp.njcp_138_24","DOIUrl":"https://doi.org/10.4103/njcp.njcp_138_24","url":null,"abstract":"<p><strong>Background: </strong>Kidney transplantation is one of the life-saving therapies for patients with end-stage renal disease, which affects a person's psychological, social, and physical well-being. How transplanted patients perceive their illness and their body can affect their physical and psychological recovery.</p><p><strong>Aim: </strong>This qualitative study was designed to evaluate self-esteem and body image in kidney transplant patients.</p><p><strong>Methods: </strong>The study involved 16 female renal transplanted patients. Data were collected using a two-part interview form developed by the investigators in accordance with the literature. We used Lundman's method to transcribe the interviews and coded the data from the interviews. The results of the study were discussed using the themes. The first three interviews were entered into MAXQDA, and then, additional interviews were analyzed.</p><p><strong>Results: </strong>Six main themes and 15 subthemes were generated based on the thematic analysis of the interviews with participants about body image and self-esteem. Themes included body acceptance, changes in body image, deterioration of social relationships, changes in self-esteem, spousal concerns, and organ perceptions. This study collected detailed data on body image, self-esteem, social relationships, and spouse/partner relationships after kidney transplantation.</p><p><strong>Conclusion: </strong>The change in participants' body image and self-esteem after kidney transplantation caused having negative feelings regarding sexual life, relationships, and social life and feeling unfamiliar with the transplanted organ.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Nigerian Journal of Clinical Practice
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1