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Impact of Changing Sterile Glove at the Time of Wound Closure to Reduce Surgical Site Infection in Women Undergoing Elective Cesarean Section; a Prospective Randomized Controlled Clinical Trial 在伤口缝合时更换无菌手套对减少择期剖腹产妇女手术部位感染的影响;一项前瞻性随机对照临床试验
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0563
Moustafa Mohamed Abbas, Alaa El Din Hamed El-Feky, Fatma Hassan Abd El-Aal
Objective: Surgical site infections (SSIs) among surgical patients are the most common nosocomial infection, accounting for 38 percent. It is estimated that SSIs develop in 2 to 5 percent of the more than 30 million patients undergoing surgical procedures each year. We aimed to assess the impact of changing sterile gloves at the time of wound closure to reduce SSI in women undergoing elective cesarean section (CS). Patients and Methods: The study was done from February 2023 to July 2023 at Ain Shams University Hospital. 220 Women were randomly distributed and blindly allocated into two groups. Group A (operative glove changing group “n=110”), Group B (usual care group “n=110”). Postoperative febrile morbidity, cellulitis, need for antibiotics for skin- or wound-related infection, and endometritis were compared between study groups. Results: Postoperative wound complications were statistically significantly higher among cases not subject to a change of sterile gloves, 28.0% vs. 9.8%. On the other hand, no differences were noted between study groups regarding operative duration 61.39 ± 7.76 vs. 59.35 ± 8.11 minutes. Conclusion: Changing sterile gloves at the time of wound closure reduces surgical site infection and associated morbidity in women undergoing elective CS.
目的:外科手术患者的手术部位感染(SSI)是最常见的院内感染,占 38%。据估计,在每年接受外科手术的 3000 多万名患者中,有 2% 到 5% 会发生 SSI。我们旨在评估在伤口闭合时更换无菌手套对减少择期剖宫产(CS)妇女 SSI 感染的影响。患者和方法:研究于 2023 年 2 月至 2023 年 7 月在艾因夏姆斯大学医院进行。220 名妇女被随机盲法分配到两组。A组(手术换手套组,n=110),B组(常规护理组,n=110)。比较研究组的术后发热发病率、蜂窝织炎、皮肤或伤口相关感染的抗生素需求以及子宫内膜炎。结果显示未更换无菌手套的病例术后伤口并发症明显高于未更换无菌手套的病例,分别为 28.0% 和 9.8%。另一方面,研究组之间在手术时间上没有差异,分别为(61.39 ± 7.76)分钟和(59.35 ± 8.11)分钟。结论在关闭伤口时更换无菌手套可减少接受择期手术的妇女的手术部位感染和相关发病率。
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引用次数: 0
Obstetric Outcomes of pregnant women with Covid-19 infection during first and second waves of Covid Pandemic in Lagos Nigeria 尼日利亚拉各斯第一波和第二波 Covid 大流行期间感染 Covid-19 孕妇的产科结果
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0565
A. Oluwole, Obodo Chioma Ethel, A. Ugwu, C. Makwe, K. Okunade, E. Owie, Ijeoma Chinenye Ohagwu, Uzoma Chinedu Ifezue, Akase Iorhen, Ngwu Hillary, Ajachukwu Placcid
Background: Coronaviruses are a group of enveloped positive-stranded RNA viruses. They constitute a very important human and animal pathogens. COVID-19, a novel coronavirus was identified towards the end of 2019 following a cluster of pneumonia in Wuhan city in China. Our study aims to document the obstetrics parameters and outcomes of pregnant women diagnosed and managed at the Lagos University Teaching Hospital, Nigeria. Methods: The study was a retrospective review of the medical records of all pregnant women admitted to the Lagos University Teaching Hospital (LUTH) COVID 19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcomes were retrieved. Results: During the study period thirty-four pregnant women with suspected COVID-19 symptoms for which nasopharyngeal samples for RTPCR for SARS-CoV-2 nucleic acid were positive were seen and managed following their admission into the isolation ward for COVID-19. Of the 34 women, 50.0% (17) of them were discharged to the antenatal clinic following recovery, 44.1% (15) had childbirth while on admission, and 5.9% (2) had maternal death. Of the 15 deliveries, 14 occurred at term with 15 babies (a set of twins) and one preterm stillbirth. Conclusion: The clinical manifestations of COVID-19 in pregnant mothers are similar to those described in the non-pregnant population as pregnancy does not seem to worsen the severity of the disease. Noticeably, severe infection occurred in women with comorbidities such as asthma and hypertensive disorders.
背景:冠状病毒是一类有包膜的正链 RNA 病毒。它们是非常重要的人类和动物病原体。COVID-19 是一种新型冠状病毒,于 2019 年底在中国武汉市的一次肺炎群中被发现。我们的研究旨在记录尼日利亚拉各斯大学教学医院诊断和管理的孕妇的产科参数和结果。研究方法本研究是对拉各斯大学教学医院(LUTH)COVID 19 隔离和治疗中心在第一波(2020 年 4 月至 2020 年 10 月)和第二波(2020 年 12 月至 2021 年 4 月)期间收治的所有孕妇的病历进行回顾性审查。对临床特征(包括 COVID 严重程度)和结果进行了检索。研究结果在研究期间,有 34 名孕妇出现疑似 COVID-19 症状,且鼻咽样本的 SARS-CoV-2 核酸 RTPCR 检测结果呈阳性。在 34 名产妇中,50.0%(17 人)在康复后出院前往产前诊所,44.1%(15 人)在入院期间分娩,5.9%(2 人)产妇死亡。在这 15 例分娩中,14 例为足月分娩,其中 15 例为双胞胎,1 例为早产死胎。结论妊娠期妇女感染 COVID-19 的临床表现与非妊娠期妇女的临床表现相似,因为妊娠似乎并不会加重疾病的严重程度。值得注意的是,患有哮喘和高血压等并发症的妇女会出现严重感染。
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引用次数: 0
Post-splenectomy thrombocytosis and survival outcomes of patients submitted to maximal effort cytoreductive surgery for advanced epithelial ovarian cancer 因晚期上皮性卵巢癌而接受最大限度细胞剥脱手术的患者脾切除术后血小板增多与生存预后
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0568
V. Pergialiotis, Dimitrios-Efthymios Vlachos, Loukas Feroussis, Vasilios Lygizos, I. Rodolakis, Konstantinos Bramis, E. Zachariou, Georgios Daskalakis, Nikolaos Thomakos, D. Haidopoulos
Background: Splenectomy is a very common procedure that is frequently necessary in cases requiring upper abdominal surgery for ovarian cancer. To date, the impact of postoperative thrombocytosis on ovarian cancer survival has not been studied. In the present retrospective cohort study we chose to evaluate the impact of post-splenectomy thrombocytosis on survival outcomes of patients with advanced epithelial ovarian cancer that were submitted to maximal effort cytoreductive procedures. Methods: We conducted a retrospective cohort study based on cases that had major debulking procedures, involving upper abdominal surgery for epithelial ovarian cancer. Results: Overall, 82 women had splenectomy of whom, 52 (63%) developed thrombocytosis. The results of the univariate analysis revealed that postoperative thrombocytosis did not increase the risk of disease recurrence (62.94 months (31.71, 93.27) vs 31.40 months (21.39, 41.41) log-rank=.683). Similar results were obtained for overall survival of included patients which was comparable among the two groups (87.50 months (53.47, 121.52) vs 47.78 months (34.30, 61.25), log-rank=.511). Logistic regression analysis revealed that only age was a predictive factor of postoperative thrombocytosis with an effect of minimal clinical importance (OR 0.94, 95% CI 0.89, 1.00). Conclusion: Post-splenectomy thrombocytosis does not affect the survival outcomes of patients with advanced epithelial ovarian cancer that undergo major debulking procedures. This might be explained by the underlying mechanisms which in the case of postoperative thrombocytosis seem to be completely disconnected from the pathophysiology of cancer.
背景:脾切除术是一种非常常见的手术,在需要进行上腹部手术治疗卵巢癌的病例中经常需要进行。迄今为止,尚未研究过术后血小板增多对卵巢癌生存率的影响。在本回顾性队列研究中,我们选择评估脾切除术后血小板增多对接受最大努力细胞清除术的晚期上皮性卵巢癌患者生存结果的影响。研究方法我们对因上皮性卵巢癌而接受上腹部手术的大手术切除病例进行了回顾性队列研究。研究结果共有 82 名妇女进行了脾脏切除术,其中 52 人(63%)出现血小板增多。单变量分析结果显示,术后血小板增多并不会增加疾病复发的风险(62.94 个月(31.71,93.27)vs 31.40 个月(21.39,41.41)log-rank=.683)。两组患者的总生存期相似(87.50 个月(53.47,121.52) vs 47.78 个月(34.30,61.25),log-rank=.511)。逻辑回归分析显示,只有年龄是术后血小板增多的一个预测因素,但其临床重要性极低(OR 0.94,95% CI 0.89,1.00)。结论脾切除术后血小板增多并不会影响接受主要切除术的晚期上皮性卵巢癌患者的生存结果。这可能与潜在的机制有关,而术后血小板增多似乎与癌症的病理生理学完全无关。
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引用次数: 0
Exploring the association of male-factor related infertility with first-trimester anomalies, aneuploidy, and biochemical markers in infertile patients undergoing ART 探讨接受抗逆转录病毒疗法的不孕患者中与男性因素相关的不孕症与头胎畸形、非整倍体和生化指标的关系
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0562
M. Zargar, Batool Asarzadeh, M. Barati
Background: A higher risk of birth defects in assisted reproductive technologies (ART) pregnancies compared to natural pregnancies has been previously reported. Objective: This retrospective study aimed to explore the association of male-factor related infertility with first-trimester anomalies, aneuploidy, and biochemical markers in infertile patients undergoing ART. Method: The complete medical records of infertile patients referred to the infertility and prenatal centers in Ahvaz, Iran during the past five years were assessed, which included ART-induced pregnancies due to male factors (n=124) and or other infertility causes (n=176). Results: The most common causes of infertility were respectively the male factor (41.3%), ovulation disorders (26%), and unexplained factors (13.3%). A significant correlation was found between the infertility causes and the history underlying systemic diseases and medication history (p<0.05). The serum levels of MoM β‐hCG and PAPP-A were significantly lower in the male factor-related infertilities than non-male factor-related infertilities (p=0.0001). The rate of fetal and placental anomalies was significantly higher in male factor-related infertilities than non-male factor-related infertilities (p=0.03). However, according to the results of multivariable logistic regression, association between the male factor-related infertility and fetal/placental anomalies was not independent of the effects of low levels of MoM β‐hCG and PAPP-A. Conclusion: Causes of infertility, particularly male factor, together with low levels of MoM β‐hCG and PAPP-A, might be associated with the high risk of fetal and placental anomalies in ART pregnancies. However, further large-scale multi-center and prospective investigations are needed to reach more accurate conclusion.
背景:以前曾有报道称,与自然妊娠相比,辅助生殖技术(ART)妊娠出现出生缺陷的风险更高。研究目的这项回顾性研究旨在探讨接受 ART 的不孕患者中,与男性因素相关的不孕症与第一胎畸形、非整倍体和生化指标的关联。研究方法对过去五年中转诊至伊朗阿瓦士市不孕不育和产前中心的不孕不育患者的完整病历进行评估,其中包括因男性因素(124 例)或其他不孕原因(176 例)导致的 ART 诱导妊娠。结果显示最常见的不孕原因分别是男性因素(41.3%)、排卵障碍(26%)和不明原因(13.3%)。不孕原因与基础系统疾病史和用药史之间存在明显相关性(P<0.05)。男性因素相关不孕症患者的血清 MoM β-hCG 和 PAPP-A 水平明显低于非男性因素相关不孕症患者(P=0.0001)。男性因素相关性不孕症的胎儿和胎盘异常率明显高于非男性因素相关性不孕症(P=0.03)。然而,根据多变量逻辑回归的结果,男性因素相关不孕症与胎儿/胎盘畸形之间的关联并不独立于低水平 MoM β-hCG 和 PAPP-A 的影响。结论不孕的原因,尤其是男性因素,加上低水平的 MoM β-hCG 和 PAPP-A,可能与 ART 妊娠中胎儿和胎盘异常的高风险有关。然而,要得出更准确的结论,还需要进一步开展大规模的多中心前瞻性研究。
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引用次数: 0
The Pathognomonic ultrasonographic findings in fetus with COVID-19 infection 感染 COVID-19 的胎儿的病理超声波检查结果
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0567
Mostafa Hassan Ragab, Mohamed Elsherbiny Hamed, Waleed Hitlar Ahmed
Aim: The main goal is to identify the pathognomonic sonographic signs for foetal SARS-CoV-2 infection and to determine whether or not transplacental SARS-CoV-2 transmission is possible. Patients and Methods: In total, 105 pregnant women with positive SARS-CoV-2 PCR swabs during the first trimester with mild or moderate infection without hospitalisation and/or oxygen support were included in this prospective comparative study, which was carried out at the ultrasound and foetal medicine unit of Ain Shams University Maternity Hospital from January 2021 to June 2023. The SARS-CoV-2 positive group was compared to the control group with inclusion and exclusion criteria. Results: In the COVID-19 group, pathognomonic ultrasonographic results were considerably more common. The COVID-19 group had a considerably higher frequency of placental calcifications and oligohydramnios. In the COVID-19 cohort, patients with positive pathognomonic ultrasonographic results had considerably higher BMIs. In the COVID-19 cohort, gestational age at infection, and BMI ≥30.0 kg/m2 were significant independent risk factors for the development of pathognomonic ultrasonographic abnormalities. Those in the control group who had positive pathognomonic ultrasonographic results were older and had higher rates of hypertension. Significant independent risk variables for the incidence of pathognomonic ultrasonographic findings in the control group included age ≥34.0 years and hypertension. Conclusion: There is no evidence of a teratogenic effect linked to maternal SARS-CoV-2 infection during the first few months of pregnancy. However, early pregnancy infection with COVID-19 is linked to pathognomonic ultrasonography findings of placental calcifications and oligohydramnios.
目的:主要目的是确定胎儿感染 SARS-CoV-2 的病理声像图征象,并确定 SARS-CoV-2 是否可能经胎盘传播。患者和方法:2021 年 1 月至 2023 年 6 月期间,艾因夏姆斯大学产科医院超声和胎儿医学科共对 105 名妊娠头三个月 SARS-CoV-2 PCR 拭子阳性、轻度或中度感染、未住院治疗和/或吸氧的孕妇进行了前瞻性比较研究。SARS-CoV-2 阳性组与对照组按照纳入和排除标准进行比较。结果在 COVID-19 组中,病理诊断性超声结果更为常见。COVID-19 组出现胎盘钙化和少水肿的频率要高得多。在 COVID-19 组中,病理诊断性超声检查结果呈阳性的患者的体重指数要高得多。在COVID-19队列中,感染时的孕龄和体重指数≥30.0 kg/m2是出现病理诊断性超声异常的重要独立风险因素。对照组中超声病理结果呈阳性的患者年龄较大,高血压发病率较高。在对照组中,年龄≥34.0 岁和高血压是出现病理诊断性超声波检查结果的重要独立风险变量。结论没有证据表明在妊娠的前几个月母体感染 SARS-CoV-2 会产生致畸效应。然而,妊娠早期感染 COVID-19 与病理超声波检查发现的胎盘钙化和少水妊娠有关。
{"title":"The Pathognomonic ultrasonographic findings in fetus with COVID-19 infection","authors":"Mostafa Hassan Ragab, Mohamed Elsherbiny Hamed, Waleed Hitlar Ahmed","doi":"10.33574/hjog.0567","DOIUrl":"https://doi.org/10.33574/hjog.0567","url":null,"abstract":"Aim: The main goal is to identify the pathognomonic sonographic signs for foetal SARS-CoV-2 infection and to determine whether or not transplacental SARS-CoV-2 transmission is possible. Patients and Methods: In total, 105 pregnant women with positive SARS-CoV-2 PCR swabs during the first trimester with mild or moderate infection without hospitalisation and/or oxygen support were included in this prospective comparative study, which was carried out at the ultrasound and foetal medicine unit of Ain Shams University Maternity Hospital from January 2021 to June 2023. The SARS-CoV-2 positive group was compared to the control group with inclusion and exclusion criteria. Results: In the COVID-19 group, pathognomonic ultrasonographic results were considerably more common. The COVID-19 group had a considerably higher frequency of placental calcifications and oligohydramnios. In the COVID-19 cohort, patients with positive pathognomonic ultrasonographic results had considerably higher BMIs. In the COVID-19 cohort, gestational age at infection, and BMI ≥30.0 kg/m2 were significant independent risk factors for the development of pathognomonic ultrasonographic abnormalities. Those in the control group who had positive pathognomonic ultrasonographic results were older and had higher rates of hypertension. Significant independent risk variables for the incidence of pathognomonic ultrasonographic findings in the control group included age ≥34.0 years and hypertension. Conclusion: There is no evidence of a teratogenic effect linked to maternal SARS-CoV-2 infection during the first few months of pregnancy. However, early pregnancy infection with COVID-19 is linked to pathognomonic ultrasonography findings of placental calcifications and oligohydramnios.","PeriodicalId":194739,"journal":{"name":"Hellenic Journal of Obstetrics and Gynecology","volume":"32 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obstetrical attitude towards performing a trial of labor after cesarean section in Greece: A cross-sectional study 希腊产科医生对剖腹产后试产的态度:横断面研究
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0564
Elpida Ralli, Kyriaki Mitta, Eirini Toulika, I. Tsakiridis, A. Mamopoulos, I. Kalogiannidis, A. Athanasiadis, T. Dagklis
Introduction: There has been a notable worldwide rise in the percentage of women delivering via cesarean section. Although cesarean section is generally considered safe, there is a possibility of significant health risks and even mortality associated with it. The aim of this study was to collect pertinent data on the perspectives of healthcare providers, particularly obstetricians, who are involved in the field of labor and delivery in Greece, regarding the choice of Trial Of Labor After Cesarean (TOLAC). Material and Methods: This was a cross-sectional study, conducted at the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; obstetricians were interviewed via certain questionnaires. Detailed analysis of the different characteristics regarding obstetricians’ background, workplace, preferences, willingness to take risks and safety concerns was conducted. These variables were compared and correlation between them was thoroughly investigated. Results: In total, 333 responses to the questionnaire were collected through Google online forms. Few obstetricians seem to enjoy taking risks, while most of them are neutral and willing to perform a planned TOLAC. It seems that as the experience of obstetricians increases, their tendency to recommend TOLAC on their own does not increase. The majority of obstetricians who had a failed TOLAC were more negative than those who had not had a failed attempt; whereas, they were willing to undertake TOLAC when the time required to transfer the women from the labor ward to the operating table was the minimum possible. Concerning the security as an important element in every aspect of obstetricians’ lives, the majority of them responded neutrally or positively. Following gender analysis, results showed that both male and female obstetricians were neutral or would avoid situations that have an uncertain outcome. Conclusion: Obstetricians and healthcare providers are willing to offer TOLAC as an option, provided that certain criteria are met and safety considerations are addressed. Finally, the acceptance and practice of TOLAC may vary between different regions, hospitals and individual healthcare providers.
导言在全球范围内,通过剖腹产分娩的产妇比例明显上升。尽管人们普遍认为剖腹产是安全的,但也有可能带来巨大的健康风险,甚至导致死亡。本研究旨在收集希腊医疗保健提供者(尤其是产科医生)对选择剖宫产后试产(TOLAC)的相关数据。材料与方法:这是一项横断面研究,在希腊塞萨洛尼基亚里士多德大学健康科学学院医学院妇产科第三系进行;通过特定问卷对产科医生进行了访谈。对产科医生的背景、工作场所、喜好、承担风险的意愿和安全顾虑等不同特征进行了详细分析。对这些变量进行了比较,并深入研究了它们之间的相关性。结果:通过谷歌在线表格共收集到 333 份问卷回复。似乎很少有产科医生喜欢冒险,而大多数产科医生持中立态度,愿意按计划实施 TOLAC。随着产科医生经验的增加,他们自行推荐 TOLAC 的倾向似乎并没有增加。与没有失败经历的产科医生相比,大多数有过 TOLAC 失败经历的产科医生都比较消极;而当将产妇从产房转移到手术台所需的时间尽可能短时,他们则愿意实施 TOLAC。安全是产科医生生活各个方面的一个重要因素,关于这一点,大多数人的回答是中立或积极的。性别分析结果显示,男性和女性产科医生均持中立态度,或会避免结果不确定的情况。结论只要符合某些标准并考虑到安全因素,产科医生和医疗服务提供者愿意将 TOLAC 作为一种选择。最后,不同地区、医院和医护人员对 TOLAC 的接受程度和做法可能有所不同。
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引用次数: 0
Intraperitoneal analgesia to reduce pain after laparoscopic hysterectomy: Randomized Controlled Trial 腹腔镜子宫切除术后减轻疼痛的腹腔内镇痛:随机对照试验
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0566
O. I. Kamel, H. M. Samour, M. F. Gomaa, S. A. Mohamed
Background: Laparoscopic hysterectomy patients report high levels of postoperative pain and inadequate pain relief. This minimally invasive procedure is difficult to manage and leads to increased opioid use, limited mobility, and higher risks of complications, delayed rehabilitation and prolonged hospital stay. Objective: To determine the analgesic efficacy of bupivacaine’s intraperitoneal instillation (IP) with dexmedetomidine as an adjuvant for postoperative pain management in laparoscopic hysterectomy. Methods: This study is a randomized control clinical trial done at the Obstetrics and Gynecology Department, Ain Shams University Hospital, within 11 months (from September 2021 to August 2022). This study’s target population was all patients enrolled in laparoscopic hysterectomy. A total of 30 patients participated in this study, and we randomly divided it into two groups equally (15 patients per group). Results: There was no significant difference between groups regarding body mass index, age, parity, obstetric history, medical history, surgical history, indication of hysterectomy, type of hysterectomy, duration of surgery, and uterus size. Visual analog scores for patients at 1-, 6-, 12-, and 24-hours post-operatively increased significantly in Group B than in Group A. Furthermore, the time required for first rescue analgesia increased significantly more in Group A than in Group B. Group A required substantially less analgesic amount than Group B. Group A had significantly shorter hospital stays than Group B. There was no statistically significant difference between groups A and B in terms of adverse effects like nausea and vomiting (p>0.05) although they were less frequent in group A. Conclusion: Intraperitoneal instillation of bupivacaine combined with dexmedetomidine during laparoscopic hysterectomy substantially reduces postoperative pain and the requirement for analgesics in the postoperative period, compared to the control group, with no adverse side effects.
背景:腹腔镜子宫切除术的患者反映术后疼痛程度高且止痛效果不佳。这种微创手术难以控制,导致阿片类药物使用量增加、活动受限、并发症风险增加、康复延迟和住院时间延长。研究目的确定布比卡因腹腔内灌注(IP)与右美托咪定作为腹腔镜子宫切除术术后疼痛治疗的辅助药物的镇痛效果。研究方法本研究是一项随机对照临床试验,在艾因夏姆斯大学医院妇产科进行,为期 11 个月(2021 年 9 月至 2022 年 8 月)。这项研究的目标人群是所有参加腹腔镜子宫切除术的患者。共有 30 名患者参与了这项研究,我们将其随机平均分为两组(每组 15 名患者)。研究结果两组患者在体重指数、年龄、胎次、产科史、病史、手术史、子宫切除术指征、子宫切除术类型、手术时间和子宫大小等方面无明显差异。B组患者在术后1小时、6小时、12小时和24小时的视觉模拟评分均显著高于A组。此外,A组患者首次抢救镇痛所需的时间显著高于B组:与对照组相比,在腹腔镜子宫切除术中腹腔内灌注布比卡因联合右美托咪定可大大减轻术后疼痛,减少术后镇痛药的用量,且无不良副作用。
{"title":"Intraperitoneal analgesia to reduce pain after laparoscopic hysterectomy: Randomized Controlled Trial","authors":"O. I. Kamel, H. M. Samour, M. F. Gomaa, S. A. Mohamed","doi":"10.33574/hjog.0566","DOIUrl":"https://doi.org/10.33574/hjog.0566","url":null,"abstract":"Background: Laparoscopic hysterectomy patients report high levels of postoperative pain and inadequate pain relief. This minimally invasive procedure is difficult to manage and leads to increased opioid use, limited mobility, and higher risks of complications, delayed rehabilitation and prolonged hospital stay. Objective: To determine the analgesic efficacy of bupivacaine’s intraperitoneal instillation (IP) with dexmedetomidine as an adjuvant for postoperative pain management in laparoscopic hysterectomy. Methods: This study is a randomized control clinical trial done at the Obstetrics and Gynecology Department, Ain Shams University Hospital, within 11 months (from September 2021 to August 2022). This study’s target population was all patients enrolled in laparoscopic hysterectomy. A total of 30 patients participated in this study, and we randomly divided it into two groups equally (15 patients per group). Results: There was no significant difference between groups regarding body mass index, age, parity, obstetric history, medical history, surgical history, indication of hysterectomy, type of hysterectomy, duration of surgery, and uterus size. Visual analog scores for patients at 1-, 6-, 12-, and 24-hours post-operatively increased significantly in Group B than in Group A. Furthermore, the time required for first rescue analgesia increased significantly more in Group A than in Group B. Group A required substantially less analgesic amount than Group B. Group A had significantly shorter hospital stays than Group B. There was no statistically significant difference between groups A and B in terms of adverse effects like nausea and vomiting (p>0.05) although they were less frequent in group A. Conclusion: Intraperitoneal instillation of bupivacaine combined with dexmedetomidine during laparoscopic hysterectomy substantially reduces postoperative pain and the requirement for analgesics in the postoperative period, compared to the control group, with no adverse side effects.","PeriodicalId":194739,"journal":{"name":"Hellenic Journal of Obstetrics and Gynecology","volume":"37 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report Of An Isolated Dextrogastria Diagnosed In First Trimester Ultrasound Screening 在第一胎超声筛查中被诊断为孤立性右侧乳房发育不良的病例报告
Pub Date : 2024-07-01 DOI: 10.33574/hjog.0569
A. Koutras, Z. Fasoulakis, G. Asimakopoulos, K. Tasias, G. Daskalakis, M. Theodora, P. Antsaklis
Isolated dextrogastria is an uncommon congenital abnormality defined by rightward stomach rotation. Although it was usually thought to be a harmless discovery with no long-term implications, potential connections with other congenital malformations have been documented. In our case, a 30-year-old primigravida’s fetus with isolated dextrogastria and an abdominal cyst gave birth at 38 weeks of pregnancy and later received a biliary atresia diagnosis. This case report contributes to the expanding collection of literature on solitary dextrogastria and highlights the importance of ongoing monitoring for any related anomalies and long-term repercussions.
孤立性胃右旋是一种不常见的先天性畸形,表现为胃向右旋转。尽管人们通常认为这是一种无害的发现,不会造成长期影响,但也有记录表明它与其他先天性畸形有潜在联系。在我们的病例中,一名 30 岁初产妇的胎儿伴有孤立性胃右旋和腹部囊肿,在妊娠 38 周时分娩,随后被诊断为胆道闭锁。本病例报告为不断增加的有关单发右侧腹腔积液的文献收集做出了贡献,并强调了持续监测相关畸形和长期影响的重要性。
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引用次数: 0
Accelerated rehabilitation after hysterectomy in reproductive age patients 育龄患者子宫切除术后加速康复
Pub Date : 2023-04-03 DOI: 10.33574/hjog.0526
O. Proshchenko, I. Ventskivska, Serhii Vasyliuk, A. Mykytiuk
Background and aims. The principles of enhanced recovery in operative gynecology, comorbidity, and a multimodal approach in perioperative support require comprehensive study and optimization, and the ambiguity of literature reports determines the relevance of this study. The aim of this study was to evaluate the parameters of perioperative monitoring after hysterectomy for uterine leiomyoma in patients of reproductive age using enhanced recovery after surgery protocols and their impact on quality of life indicators. Materials and methods. To evaluate the effectiveness of the enhanced recovery protocol after hysterectomy, two groups were formed: the main prospective group, which included 46 patients, who underwent vaginal hysterectomy without appendages and 36 patients with abdominal hysterectomy, who used enhanced recovery after surgery (ERAS) protocols. The comparison group (group of standard management) included 44 patients who underwent vaginal hysterectomy without appendages and 34 patients with abdominal hysterectomy. The main parameters of monitoring were the postoperative pain level, intraoperative blood loss, diuresis rate, the timing of urinary catheter removal and recovery of peristalsis, as well as individual activation of motor activity. Results. When using the principles of ERAS, the quantitative assessment of pain level (“absence of pain”) was 1.6 times more severe compared to the data of the comparison group; the timing of urinary catheter removal was 2.0 times shorter, drain removal – 2.7 times shorter, recovery of peristalsis – 1.9 times shorter and individual activation of motor activity – 2.9 times earlier than in patients of the comparison group. Conclusions. Studies have demonstrated the feasibility of using laparoscopic technology in combination with the ERAS, which demonstrates a fall in the volume of intraoperative blood loss, a decrease in blood and fluid balance, a shortening of the time of invasive intravascular intervention, allows to improve the course of the early postoperative period, relieve postoperative pain syndrome, reduce the risk of intestinal paresis, shorten the rehabilitation period, and, as a result, improve quality of life indicators.
背景和目的。手术妇科提高康复的原则、合并症、围手术期支持的多模式方式需要全面研究和优化,文献报道的模糊性决定了本研究的相关性。本研究的目的是评估育龄期子宫平滑肌瘤患者子宫切除术后围手术期监测参数,采用增强术后恢复方案及其对生活质量指标的影响。材料和方法。为了评估子宫切除术后增强恢复方案的有效性,我们分为两组:主要前瞻性组,包括46例接受阴道无附件子宫切除术的患者和36例接受腹部子宫切除术的患者,他们采用手术后增强恢复(ERAS)方案。对照组(标准处理组)包括44例阴道无附件子宫切除术患者和34例腹部子宫切除术患者。监测的主要参数为术后疼痛程度、术中出血量、利尿率、拔除导尿管时间及肠蠕动恢复情况、个体运动活动激活情况。结果。当采用ERAS原则时,疼痛程度(“无疼痛”)的定量评估比对照组严重1.6倍;与对照组患者相比,拔管时间缩短2.0倍,引流时间缩短2.7倍,蠕动恢复时间缩短1.9倍,个体运动活动激活时间提前2.9倍。结论。研究表明,腹腔镜技术与ERAS联合应用的可行性,术中出血量下降,血液平衡下降,血管内介入时间缩短,改善术后早期病程,缓解术后疼痛综合征,降低肠瘫风险,缩短康复期。提高生活质量指标。
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引用次数: 1
Non immune hydrops fetalis due to Parvovirus B19 infection. A case report 细小病毒B19感染引起的非免疫性水肿胎儿。病例报告
Pub Date : 2023-04-03 DOI: 10.33574/hjog.0527
M. Chatziioannou, Z. Fasoulakis, M. Theodora, G. Daskalakis, P. Antsaklis
Backround: The term “hydrops fetalis” refers to excessive accumulation of pathologic serous fluid within the fetal soft tissues and body cavities. There are two categories, the immune and the nonimmune hydrops (NIHF). Currently 90 percent of cases of hydrops are nonimmune, because of the decrease of incidence of immune with the advent of anti-D immune globulin. Case presentation: We present a case of Parvovirus B19 (PB19) infection that resulted in NIHF. Fetus had severe ascites, mild pericardial effusion and mild myocardial dilation, that appeared during the 30th gestational week. Fetal evaluation with sonography was repeated every week and the fetal growth curves, Dopplers and amniotic fluid index were normal. Each week there was a gradual recession of the effusions until the 36th gestational week, when they eventually resolved without any treatment. After delivery, the neonate was symptom – free. Conclusions: The cause of NIHF is identified in at least 60 percent prenatally and in more than 80 percent postnatally, while only 40 percent of pregnancies with NIHF result in a liveborn neonate. The prognosis is heavily dependent on etiology. Diaplacental transmission of PB19 on second trimester can cause fetal complications like hydrops, premature rapture of membranes, even fetal loss in about 30 percent. These cases should be closely followed in a Fetal Medicine Unit, especially if there is evidence of fetal anemia or hydrops.
背景:术语“胎儿积水”是指病理性浆液在胎儿软组织和体腔内的过度积累。有两种类型,免疫和非免疫水肿(NIHF)。随着抗d免疫球蛋白的出现,免疫性的发生率降低,目前90%的水痘病例是非免疫性的。病例报告:我们报告一例细小病毒B19 (PB19)感染导致NIHF。妊娠30周胎儿出现严重腹水、轻度心包积液和轻度心肌扩张。每周复查超声,胎儿生长曲线、多普勒指数、羊水指数均正常。每周积液逐渐减少,直到妊娠36周,积液在没有任何治疗的情况下最终消失。分娩后,新生儿无症状。结论:至少60%的产前和80%以上的产后NIHF的病因被确定,而只有40%的NIHF妊娠导致活产新生儿。预后很大程度上取决于病因。PB19在妊娠中期经胎盘传播可引起胎儿并发症,如水肿、胎膜早破,甚至30%的胎儿流产。这些病例应密切跟踪胎儿医学单位,特别是如果有证据表明胎儿贫血或水肿。
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引用次数: 0
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Hellenic Journal of Obstetrics and Gynecology
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