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Effects of Ethanol Locks on Burst Pressure for Small Caliber Nonpower Injectable Peripherally Inserted Central Catheters. 乙醇锁对小口径无动力注射外周置入中心导管爆破压的影响。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003604
Mark D Weber, Adam S Himebauch, Jeremy C Zuckerberg, Karla Resendiz, Thomas Conlon
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引用次数: 0
Prioritizing Childhood Pneumonia to Achieve Global Health Targets-Insights From the Pediatric Acute and Critical Care Medicine Asian Network (PACCMAN) Cohort. 确定儿童肺炎的优先次序以实现全球健康目标--来自亚洲儿科急症和重症医学网络 (PACCMAN) 队列的启示。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003606
Brenda M Morrow
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引用次数: 0
A Breath of Fresh Air: The Role of Airway Anomalies on Outcomes in Congenital Heart Disease. 呼吸新鲜空气:气道异常对先天性心脏病预后的影响。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003616
Avital Ludomirsky, Maryam Y Naim
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引用次数: 0
Airway Anomalies in Pediatric Patients After Surgery for Congenital Heart Disease: Single-Center Retrospective Cohort Study, Taiwan, 2017-2020. 先天性心脏病手术后小儿患者的气道异常:2017-2020年台湾单中心回顾性队列研究。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-08-06 DOI: 10.1097/PCC.0000000000003592
Jeng-Hung Wu, En-Ting Wu, Heng-Wen Chou, Ching-Chia Wang, Frank Leigh Lu, Yi-Chia Wang, Chi-Hisang Huang, Shyh-Jye Chen, Yih-Sharng Chen, Shu-Chien Huang

Objectives: Airway anomalies increase risk of morbidity and mortality in postoperative pediatric patients with congenital heart disease (CHD). We aimed to identify airway anomalies and the association with intermediate outcomes in patients undergoing surgery for CHD.

Design: Single-center, hospital-based retrospective study in Taiwan, 2017-2020.

Setting: A tertiary referral hospital in Taiwan.

Patients: All pediatric patients who underwent surgery for CHD and were admitted to the PICU and had data about airway evaluation by cardiopulmonary CT scan or bronchoscopy.

Interventions: None.

Measurements and main results: Among 820 CHD patients identified as having undergone airway evaluation in the PICU, 185 (22.6%) were diagnosed with airway anomalies, including structural lesions in 146 of 185 (78.9%), and dynamic problems were seen in 87 of 185 (47.0%). In this population, the explanatory factors associated with greater odds (odds ratio [OR]) of airway anomaly were premature birth (OR, 1.90; p = 0.002), genetic syndromes (OR, 2.60; p < 0.001), and in those with preoperative ventilator use (OR, 4.28; p < 0.001). In comparison to those without airway anomalies, the presence of airway anomalies was associated with higher hospital mortality (11.4% vs. 2.7%; p < 0.001), prolonged intubation days (8 d [1-27 d] vs. 1 d [1-5 d]; p < 0.001), longer PICU length of stay (23 d [8-81 d] vs. 7 d [4-18 d]; p < 0.001), and greater hazard of intermediate mortality (adjusted hazard ratio, 2.60; p = 0.001).

Conclusions: In our single-center retrospective study, 2017-2020, between one-in-five and one-in-four of our postoperative CHD patients undergoing an airway evaluation had airway anomalies. Factors associated with greater odds of airway anomaly included, those with premature birth, or genetic syndromes, and preoperative ventilator use. Overall, in patients undergoing airway evaluation, the finding of an airway anomalies was associated with longer postoperative intubation duration and greater hazard of intermediate mortality.

目的:气道异常会增加先天性心脏病(CHD)儿科患者术后的发病率和死亡率。我们旨在确定气道异常以及气道异常与先天性心脏病手术患者中期预后的关系:2017-2020年在台湾进行的基于医院的单中心回顾性研究:台湾一家三级转诊医院:所有接受CHD手术并入住PICU的儿科患者,且有心肺CT扫描或支气管镜检查气道评估数据:测量和主要结果在PICU接受气道评估的820名CHD患者中,185人(22.6%)被诊断为气道异常,其中146人(78.9%)存在结构性病变,87人(47.0%)存在动态问题。在这一人群中,与气道异常几率(几率比 [OR])较大相关的解释性因素有早产(OR,1.90;P = 0.002)、遗传综合征(OR,2.60;P < 0.001)以及术前使用呼吸机者(OR,4.28;P < 0.001)。与无气道异常的患者相比,气道异常与较高的住院死亡率(11.4% vs. 2.7%;P < 0.001)、较长的插管天数(8 天 [1-27 天] vs. 1 天 [1-5 天];P < 0.001)、较低的死亡率(1.5% vs. 1.5%;P < 0.001)、较高的插管天数(1 天 [1-27 天] vs. 1 天 [1-5 天];P < 0.001)相关。1天 [1-5 天];p < 0.001)、PICU住院时间延长(23天 [8-81 天] vs. 7天 [4-18 天];p < 0.001)以及中度死亡风险增加(调整后危险比为2.60;p = 0.001):在我们的单中心回顾性研究(2017-2020年)中,接受气道评估的CHD术后患者中,有五分之一到四分之一存在气道异常。与气道异常几率增大相关的因素包括:早产、遗传综合征以及术前使用呼吸机。总体而言,在接受气道评估的患者中,发现气道异常与术后插管时间延长和中度死亡率增加有关。
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引用次数: 0
Fluid Management in Critically Ill Children: Single-Center Retrospective Comparison of Trauma and Postoperative Patients, 2020-2022. 重症儿童的输液管理:2020-2022 年创伤和术后患者的单中心回顾性比较。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-08-12 DOI: 10.1097/PCC.0000000000003590
Yeu Sanz Wu, Tania Gennell, Chloe Porigow, Weijia Fan, Jeanne Rubsam, Nicolino Valerio Dorrello, Steven Stylianos, Vincent P Duron

Objective: Injury and surgery both represent well-defined starting points of a predictable inflammatory response, but the consequent response to IV fluids has not been studied. We aimed to review and compare our single-center fluid management strategies in these two populations.

Design: Retrospective cohort study from January 2020 to July 2022. The primary outcome was total IV fluid volume administered. Net fluid balances and select clinical outcomes were also evaluated.

Setting: Single tertiary academic center and level 1 pediatric trauma center in New York.

Patients: A dataset of critically ill trauma and surgical patients aged 0-18 years who were admitted to the PICU, 2020-2022. Trauma patients had at least moderate traumatic injuries (Injury Severity Score ≥ 9) and surgical patients had at least a 1-hour operation time.

Interventions: None.

Measurements and main results: We identified 25 trauma and 115 surgical patients. During the first 5 days of hospitalization, we did not identify an association between grouping and total IV fluids administered and fluid balance in the prehospital, emergency department, and operating room ( p = 0.90 and p = 0.79), even when adjusted for weight ( p = 0.96). Time trend graphs of net fluid balance and IV fluid administered illustrated analogous fluid requirement and response with the transition from net positive to net negative fluid balance between 48 and 72 hours. There was an association between total IV fluid and ventilator requirement ( p = 0.003).

Conclusions: Critically ill pediatric trauma and postoperative patients seem to have similar fluid management and balance after injury or surgery. In our opinion, these two critically ill populations could be combined in large prospective studies on optimal fluid therapy in critically ill children.

目的:受伤和手术都是可预测炎症反应的明确起点,但对静脉输液的相应反应尚未进行研究。我们旨在回顾和比较我们在这两种人群中的单中心输液管理策略:设计:2020 年 1 月至 2022 年 7 月的回顾性队列研究。主要结果是静脉输液总量。研究还评估了净液体平衡和部分临床结果:研究地点:纽约的一家三级学术中心和一级儿科创伤中心:患者:2020-2022年期间入住儿童重症监护病房的0-18岁重症创伤和手术患者数据集。外伤患者至少有中度外伤(受伤严重程度评分≥9分),手术患者至少有1小时的手术时间:测量和主要结果我们确定了 25 名外伤患者和 115 名手术患者。在住院的前 5 天,我们没有发现分组和静脉输液总量与院前、急诊科和手术室的体液平衡之间存在关联(p = 0.90 和 p = 0.79),即使根据体重进行调整也是如此(p = 0.96)。净体液平衡和静脉输液的时间趋势图显示了类似的体液需求和反应,在 48 小时和 72 小时之间从净正体液平衡过渡到净负体液平衡。静脉输液总量与呼吸机需求量之间存在关联(p = 0.003):结论:儿科创伤重症患者和术后重症患者在受伤或手术后的体液管理和平衡情况似乎相似。我们认为,可以将这两种危重病人合并到关于危重症儿童最佳液体疗法的大型前瞻性研究中。
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引用次数: 0
Unraveling the Blood Biomaterial Interaction During Extracorporeal Membrane Oxygenation. 揭示体外膜氧合过程中血液与生物材料的相互作用
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003615
Gail M Annich, Dylan Ginter, Melissa Reynolds
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引用次数: 0
Comprehensive Characterization of Surface-Bound Proteins and Measurement of Fibrin Fiber Thickness on Extracorporeal Membrane Oxygenation Circuits Collected From Patients. 体外膜氧合回路表面结合蛋白的综合表征和患者体内纤维蛋白纤维厚度的测量。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-08-13 DOI: 10.1097/PCC.0000000000003591
Tengyi Cai, Samantha J Emery-Corbin, Conor McCafferty, Suelyn Van Den Helm, Natasha Letunica, Chantal Attard, Rebecca Barton, Stephen Horton, Steve Bottrell, Bradley Schultz, Graeme MacLaren, Roberto Chiletti, Derek Best, Amy Johansen, Fiona Newall, Warwick Butt, Yves d'Udekem, Laura F Dagley, Jumana M Yousef, Paul Monagle, Vera Ignjatovic

Objective: To characterize surface-bound proteins and to measure the thickness of fibrin fibers bound to extracorporeal membrane oxygenation (ECMO) circuits used in children.

Design: Single-center observational prospective study, April to November 2021.

Setting: PICU, Royal Children's Hospital, Melbourne, Australia.

Patients: Patients aged less than 18 years on venoarterial ECMO and without preexisting disorder.

Interventions: None.

Measurements and main results: ECMO circuits were collected from six patients. Circuit samples were collected from five different sites, and subsequently processed for proteomic and scanning electron microscopy (SEM) studies. The concentration of proteins bound to ECMO circuit samples was measured using a bicinchoninic acid protein assay, whereas characterization of the bound proteome was performed using data-independent acquisition mass spectrometry. The Reactome Over-representation Pathway Analyses tool was used to identify functional pathways related to bound proteins. For the SEM studies, ECMO circuit samples were prepared and imaged, and the thickness of bound fibrin fibers was measured using the Fiji ImageJ software, version 1.53c ( https://imagej.net/software/fiji/ ). Protein binding to ECMO circuit samples and fibrin networks showed significant intra-circuit and interpatient variation. The median (range) total protein concentration was 19.0 (0-76.9) μg/mL, and the median total number of proteins was 2011 (1435-2777). A total of 933 proteins were commonly bound to ECMO circuit samples from all patients and were functionally involved in 212 pathways, with signal transduction, cell cycle, and metabolism of proteins being the top three pathway categories. The median intra-circuit fibrin fiber thickness was 0.20 (0.15-0.24) μm, whereas the median interpatient fibrin fiber thickness was 0.18 (0.15-0.21) μm.

Conclusions: In this report, we have characterized proteins and fiber fibrin thickness bound to ECMO circuits in six children. The techniques and approaches may be useful for investigating interactions between blood, coagulation, and the ECMO circuit and have the potential for circuit design.

目的:确定表面结合蛋白的特征,并测量用于儿童的体外膜肺氧合(ECMO)回路的纤维蛋白纤维厚度:描述体外膜氧合(ECMO)回路表面结合蛋白的特征,并测量结合在儿童体外膜氧合回路上的纤维蛋白纤维的厚度:单中心前瞻性观察研究,2021 年 4 月至 11 月:地点:澳大利亚墨尔本皇家儿童医院 PICU:干预措施:无:测量和主要结果收集了六名患者的 ECMO 循环样本。从五个不同部位采集回路样本,随后进行蛋白质组学和扫描电子显微镜(SEM)研究。使用双喹啉酸蛋白质测定法测量了 ECMO 循环样本中结合的蛋白质浓度,而结合的蛋白质组的特征描述则使用数据独立采集质谱法进行。Reactome 过度呈现通路分析工具用于确定与结合蛋白相关的功能通路。在扫描电子显微镜研究中,制备了 ECMO 电路样本并进行了成像,使用 Fiji ImageJ 软件 1.53c 版(https://imagej.net/software/fiji/)测量了结合纤维蛋白纤维的厚度。蛋白质与 ECMO 循环样本和纤维蛋白网络的结合在循环内和患者间存在显著差异。蛋白质总浓度的中位数(范围)为 19.0 (0-76.9) μg/mL,蛋白质总数的中位数为 2011 (1435-2777)。所有患者的 ECMO 循环样本中通常结合有 933 种蛋白质,它们在功能上参与了 212 种通路,其中信号转导、细胞周期和蛋白质代谢是前三大通路类别。回路内纤维蛋白纤维厚度的中位数为 0.20 (0.15-0.24) μm,而患者间纤维蛋白纤维厚度的中位数为 0.18 (0.15-0.21) μm:在这份报告中,我们描述了六名患儿 ECMO 循环中结合的蛋白质和纤维蛋白厚度。这些技术和方法可用于研究血液、凝血和 ECMO 电路之间的相互作用,并有可能用于电路设计。
{"title":"Comprehensive Characterization of Surface-Bound Proteins and Measurement of Fibrin Fiber Thickness on Extracorporeal Membrane Oxygenation Circuits Collected From Patients.","authors":"Tengyi Cai, Samantha J Emery-Corbin, Conor McCafferty, Suelyn Van Den Helm, Natasha Letunica, Chantal Attard, Rebecca Barton, Stephen Horton, Steve Bottrell, Bradley Schultz, Graeme MacLaren, Roberto Chiletti, Derek Best, Amy Johansen, Fiona Newall, Warwick Butt, Yves d'Udekem, Laura F Dagley, Jumana M Yousef, Paul Monagle, Vera Ignjatovic","doi":"10.1097/PCC.0000000000003591","DOIUrl":"10.1097/PCC.0000000000003591","url":null,"abstract":"<p><strong>Objective: </strong>To characterize surface-bound proteins and to measure the thickness of fibrin fibers bound to extracorporeal membrane oxygenation (ECMO) circuits used in children.</p><p><strong>Design: </strong>Single-center observational prospective study, April to November 2021.</p><p><strong>Setting: </strong>PICU, Royal Children's Hospital, Melbourne, Australia.</p><p><strong>Patients: </strong>Patients aged less than 18 years on venoarterial ECMO and without preexisting disorder.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>ECMO circuits were collected from six patients. Circuit samples were collected from five different sites, and subsequently processed for proteomic and scanning electron microscopy (SEM) studies. The concentration of proteins bound to ECMO circuit samples was measured using a bicinchoninic acid protein assay, whereas characterization of the bound proteome was performed using data-independent acquisition mass spectrometry. The Reactome Over-representation Pathway Analyses tool was used to identify functional pathways related to bound proteins. For the SEM studies, ECMO circuit samples were prepared and imaged, and the thickness of bound fibrin fibers was measured using the Fiji ImageJ software, version 1.53c ( https://imagej.net/software/fiji/ ). Protein binding to ECMO circuit samples and fibrin networks showed significant intra-circuit and interpatient variation. The median (range) total protein concentration was 19.0 (0-76.9) μg/mL, and the median total number of proteins was 2011 (1435-2777). A total of 933 proteins were commonly bound to ECMO circuit samples from all patients and were functionally involved in 212 pathways, with signal transduction, cell cycle, and metabolism of proteins being the top three pathway categories. The median intra-circuit fibrin fiber thickness was 0.20 (0.15-0.24) μm, whereas the median interpatient fibrin fiber thickness was 0.18 (0.15-0.21) μm.</p><p><strong>Conclusions: </strong>In this report, we have characterized proteins and fiber fibrin thickness bound to ECMO circuits in six children. The techniques and approaches may be useful for investigating interactions between blood, coagulation, and the ECMO circuit and have the potential for circuit design.</p>","PeriodicalId":19760,"journal":{"name":"Pediatric Critical Care Medicine","volume":" ","pages":"1017-1025"},"PeriodicalIF":4.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a Comprehensive Algorithm for PICU Patients With New Fever or Instability: Association of Clinical Decision Support With Testing Practices. 评估针对新发热或病情不稳定的 PICU 患者的综合算法:临床决策支持与测试实践的关联。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-07-19 DOI: 10.1097/PCC.0000000000003582
Matthew S Linz, Lauren D Booth, Aaron M Milstone, David C Stockwell, Anna C Sick-Samuels

Objectives: Previously, we implemented a comprehensive decision support tool, a "New Fever Algorithm," to support the evaluation of PICU patients with new fever or instability. This tool was associated with a decline in culture rates without safety concerns. We assessed the impact of the algorithm on testing practices by identifying the proportion of cultures pre- vs. post-implementation that were discordant with algorithm guidance and may have been avoidable.

Design: Retrospective evaluation 12 months pre- vs. post-quality improvement intervention.

Setting: Single-center academic PICU and pediatric cardiac ICU.

Subjects: All admitted patients.

Interventions: Implementing the "New Fever Algorithm" in July 2020.

Measurements and main results: Patient medical records were reviewed to categorize indications for all blood, respiratory, and urine cultures. Among cultures obtained for new fever or new clinical instability, we assessed specific testing patterns that were discordant from the algorithm's guidance such as blood cultures obtained without documented concern for sepsis without initiation of antibiotics, respiratory cultures without respiratory symptoms, urine cultures without a urinalysis or pyuria, and pan-cultures (concurrent blood, respiratory, and urine cultures). Among 2827 cultures, 1950 (69%) were obtained for new fever or instability. The proportion of peripheral blood cultures obtained without clinical concern for sepsis declined from 18.6% to 10.4% ( p < 0.0007). Respiratory cultures without respiratory symptoms declined from 41.5% to 27.4% ( p = 0.01). Urine cultures without a urinalysis did not decline (from 27.6% to 25.1%). Urine cultures without pyuria declined from 83.0% to 73.7% ( p = 0.04). Pan-cultures declined from 22.4% to 10.6% ( p < 0.0001). Overall, algorithm-discordant testing declined from 39% to 30% ( p < 0.0001).

Conclusions: The majority of cultures obtained were for new fever or instability and introduction of the "New Fever Algorithm" was associated with reductions in algorithm-discordant testing practices and pan-cultures. There remain opportunities for improvement and additional strategies are warranted to optimize testing practices for in this complex patient population.

目的:此前,我们采用了一种综合决策支持工具--"新发热算法",以支持对新发热或病情不稳定的重症监护病房患者进行评估。该工具降低了培养率,但不存在安全问题。我们评估了该算法对检测实践的影响,确定了实施前与实施后与算法指导不一致且可能可以避免的培养比例:设计:质量改进干预前后 12 个月的回顾性评估:研究对象: 所有入院患者:干预措施干预措施:2020 年 7 月实施 "新发热算法":回顾患者病历,对所有血液、呼吸道和尿液培养的适应症进行分类。在因新发热或新的临床不稳定性而进行的培养中,我们评估了与算法指导不一致的特定检测模式,如在无脓毒症记录的情况下进行血液培养,且未开始使用抗生素;在无呼吸道症状的情况下进行呼吸道培养;在无尿检或脓尿的情况下进行尿培养;以及泛培养(同时进行血液、呼吸道和尿液培养)。在 2827 份培养中,1950 份(69%)是因新发热或病情不稳定而获得的。无败血症临床症状的外周血培养比例从 18.6% 降至 10.4%(p < 0.0007)。无呼吸道症状的呼吸道培养从 41.5% 降至 27.4%(p = 0.01)。未进行尿检的尿培养率没有下降(从 27.6% 降至 25.1%)。无脓尿的尿培养率从 83.0% 降至 73.7%(p = 0.04)。泛培养从 22.4% 降至 10.6%(p < 0.0001)。总体而言,算法不一致的检测从 39% 降至 30%(p < 0.0001):大多数培养都是针对新发热或不稳定的情况,而 "新发热算法 "的引入与算法不一致的检测实践和泛培养的减少有关。但仍有改进的余地,需要采取更多策略来优化这一复杂患者群体的检测方法。
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引用次数: 0
Enriching the Field: The Ongoing Story of Acute Kidney Injury Diagnosis and Prognostication in Children With Septic Shock. 丰富领域:脓毒性休克患儿急性肾损伤诊断和预后的持续故事。
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003614
Tara M Neumayr
{"title":"Enriching the Field: The Ongoing Story of Acute Kidney Injury Diagnosis and Prognostication in Children With Septic Shock.","authors":"Tara M Neumayr","doi":"10.1097/PCC.0000000000003614","DOIUrl":"https://doi.org/10.1097/PCC.0000000000003614","url":null,"abstract":"","PeriodicalId":19760,"journal":{"name":"Pediatric Critical Care Medicine","volume":"25 11","pages":"1068-1070"},"PeriodicalIF":4.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Making Waves With Point-of-Care Ultrasound; Investment Begets Impact at the ICU Bedside? 利用护理点超声波掀起波澜;投资能否在重症监护病房床旁产生影响?
IF 4 2区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-11-04 DOI: 10.1097/PCC.0000000000003617
Vidit Bhargava, David B Kantor, Erik Su
{"title":"Making Waves With Point-of-Care Ultrasound; Investment Begets Impact at the ICU Bedside?","authors":"Vidit Bhargava, David B Kantor, Erik Su","doi":"10.1097/PCC.0000000000003617","DOIUrl":"https://doi.org/10.1097/PCC.0000000000003617","url":null,"abstract":"","PeriodicalId":19760,"journal":{"name":"Pediatric Critical Care Medicine","volume":"25 11","pages":"1065-1068"},"PeriodicalIF":4.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Pediatric Critical Care Medicine
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