Pub Date : 2021-01-01DOI: 10.1016/B978-0-323-24485-5.00084-X
M. Papich
{"title":"Amoxicillin and Clavulanate Potassium","authors":"M. Papich","doi":"10.1016/B978-0-323-24485-5.00084-X","DOIUrl":"https://doi.org/10.1016/B978-0-323-24485-5.00084-X","url":null,"abstract":"","PeriodicalId":19792,"journal":{"name":"Papich Handbook of Veterinary Drugs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79219246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1016/s0099-5428(08)60168-9
M. G. Papich
{"title":"Heparin Sodium","authors":"M. G. Papich","doi":"10.1016/s0099-5428(08)60168-9","DOIUrl":"https://doi.org/10.1016/s0099-5428(08)60168-9","url":null,"abstract":"","PeriodicalId":19792,"journal":{"name":"Papich Handbook of Veterinary Drugs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81043994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, trandolapril is converted by de-esterification in the liver into its active form trandolaprilat. T randolaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. T his prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. T randolaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. Qeios · Definition, February 8, 2020
{"title":"Trandolapril","authors":"M. Papich","doi":"10.18578/bnf.533283865","DOIUrl":"https://doi.org/10.18578/bnf.533283865","url":null,"abstract":"A non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, trandolapril is converted by de-esterification in the liver into its active form trandolaprilat. T randolaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. T his prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. T randolaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. Qeios · Definition, February 8, 2020","PeriodicalId":19792,"journal":{"name":"Papich Handbook of Veterinary Drugs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89561660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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