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2022 15th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI)最新文献

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SMOTE-LASSO-DeepNet Framework for Cancer Subtyping from Gene Expression Data 基于基因表达数据的癌症亚型分型SMOTE-LASSO-DeepNet框架
Yashpal Singh, Seba Susan
Cancer subtyping from gene expression data is trending research in the field of bioinformatics. Classification of gene expression data is a challenging task due to the small number of samples and large number of features involved. The problem is further complicated due to the strong class imbalance issue prevalent in gene expression datasets. The challenge here is to find an end-to-end machine learning solution to classify cancer subtypes from small sample, high-dimensional, imbalanced gene expression datasets. In this study, we propose a SMOTE-LASSO-DeepNet framework for the identification of cancer subtypes from gene expression data. The proposed framework balances the training set using SMOTE, and then finds the most informative genes using LASSO. The balanced and pruned training set is then applied as input to a deep neural network (DeepNet) with four hidden layers having 512, 256, 128 and 64 neurons respectively. We tested our framework on four different cancer gene expression datasets: Leukemia, Lung cancer, Brain cancer and Breast cancer. It is observed from the results that our proposed SMOTE-LASSO-DeepNet framework performs consistently best as compared to the existing methods.
基于基因表达数据的癌症亚型分析是生物信息学领域的研究热点。由于样本数量少,特征数量多,基因表达数据的分类是一项具有挑战性的任务。由于基因表达数据集中普遍存在强烈的类不平衡问题,使问题进一步复杂化。这里的挑战是找到一个端到端的机器学习解决方案,从小样本、高维、不平衡的基因表达数据集中对癌症亚型进行分类。在这项研究中,我们提出了一个SMOTE-LASSO-DeepNet框架,用于从基因表达数据中识别癌症亚型。该框架使用SMOTE平衡训练集,然后使用LASSO找到信息量最大的基因。然后将平衡和修剪的训练集作为输入应用到深度神经网络(DeepNet)中,该网络具有四个隐藏层,分别具有512、256、128和64个神经元。我们在四种不同的癌症基因表达数据集上测试了我们的框架:白血病、肺癌、脑癌和乳腺癌。从结果中可以看出,与现有方法相比,我们提出的SMOTE-LASSO-DeepNet框架的性能始终最好。
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引用次数: 1
Acceleration of Multi-b-value Multi-shot Diffusion-weighted Imaging using Interleaved Keyhole-EPI and Locally Low Rank Reconstruction 交错Keyhole-EPI和局部低秩重构加速多b值多镜头扩散加权成像
Xin Tang, Juan Gao, Fan Yang, Chenxi Hu
Muti-b-value Diffusion Weighted Imaging (DWI) is commonly used in clinical and neuroscientific applications. The traditional single-shot Echo-Planer Imaging (EPI) sequence suffers from low image resolution. Although the multi-shot EPI sequence can increase spatial resolution, the multi-shot k-space sampling causes linearly increased scan time. An interleaved EPI acquisition can significantly reduce the scan time; however, the dynamic change of image phase and image contrast causes aliasing artifacts. To improve the scan efficiency and preserve the image quality, an interleaved keyhole-EPI multi-b-value multi-shot sequence is proposed, with the image reconstruction formulated as a Locally Low Rank (LLR) constrained problem. The resultant cost function is minimized by a computationally efficient ADMM algorithm. The proposed method was compared with interleaved EPI acquisition using the state-of-the-art SPatial-Angular Locally Low Rank (SPA-LLR) algorithm in two healthy subjects. The results showed that the proposed method achieved superior image quality and fewer aliasing artifacts compared with the state-of-the-art method in both the raw DWI images and Apparent Diffusion Coefficient (ADC) maps.
多b值弥散加权成像(DWI)广泛应用于临床和神经科学领域。传统的单镜头回波平面成像(EPI)序列存在图像分辨率低的问题。虽然多镜头EPI序列可以提高空间分辨率,但多镜头k空间采样导致扫描时间线性增加。交错的EPI采集可以显著缩短扫描时间;然而,图像相位和图像对比度的动态变化会引起混叠伪影。为了提高扫描效率和保持图像质量,提出了一种交错keyhole-EPI多b值多镜头序列,并将图像重建表述为局部低秩约束问题。所得到的代价函数通过计算效率高的ADMM算法最小化。将该方法与基于空间-角度局部低秩(spatial - angle local Low Rank, SPA-LLR)算法的交错EPI采集方法在两名健康受试者身上进行了比较。结果表明,该方法在原始DWI图像和表观扩散系数(ADC)图上均取得了较好的图像质量和较少的混叠伪影。
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引用次数: 0
Research on Smooth Edge Feature Recognition Method for Aerial Image Segmentation 航空图像分割中的光滑边缘特征识别方法研究
Heng Wang, Yanrong Yuan, Chuangang Zhuang, Rui Shi, Jiamei Zhao, Xinyi Guo, Jintian Tang
With the continuous development of aerial photography technology, its imaging quality is higher and higher, and the post-processing technology requirements for aerial images are getting higher and higher. Aerial image target recognition technology has been a hot research content in recent years. This technology relies on computer vision and image processing algorithm. But aerial images have certain particularities, including long shooting distances, complex image backgrounds, and variable target angles. The above factors can easily lead to indistinguishability between the target boundary and the background information of the aerial images. In order to solve that problem, a smooth edge feature information recognition method for aerial images is proposed. The energy fitting term related to the gray value inside and outside the curve is introduced, with that the method can get rid of the dependence of the detection operator as the stopping function of the curve evolution. In order to prevent the algorithm from falling into a local optimal solution in the iterative process, the Dirac function with a non-zero value in the domain is adopted. With synthetic and natural images, the effectiveness and accuracy of the method is verified. The robustness of the algorithm will be verified in the future researches by the acquired aerial image data set.
随着航空摄影技术的不断发展,其成像质量越来越高,对航空影像的后处理技术要求也越来越高。航空图像目标识别技术是近年来研究的热点内容。该技术依赖于计算机视觉和图像处理算法。但航拍图像具有一定的特殊性,拍摄距离长,图像背景复杂,目标角度多变。以上因素容易导致航拍图像的目标边界与背景信息难以区分。为了解决这一问题,提出了一种航空图像平滑边缘特征信息识别方法。引入与曲线内外灰度值相关的能量拟合项,使该方法摆脱了对检测算子作为曲线演化停止函数的依赖。为了防止算法在迭代过程中陷入局部最优解,采用了域内非零值的Dirac函数。通过合成图像和自然图像,验证了该方法的有效性和准确性。该算法的鲁棒性将在未来的研究中通过获取的航空图像数据集进行验证。
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引用次数: 1
Coarse-to-Fine Tranformer for articular disc of the temporomandibular joint Segmentation
Chenglin Wu, Xuran Zhou, Guannan Chen
The most important subtypes of joint abnormalities in patients with temporomandibular disorders are different forms of disc displacement and deformation. An effective segmentation model for jaw joint detection to support the diagnosis of TMJ disease on magnetic resonance imaging is very crucial. Data for this study were obtained from 204 MRI images of patients with articular discs and the corresponding MRI segmentation labels of the temporomandibular joints. These images were used to evaluate four deep learning-based semantic segmentation methods. Using a multi-scale structured C2Ftrans segmentation model transformed from coarse to fine, it describes medical image segmentation as a coarse to fine process. It is able to perform accurate target boundary segmentation with lower computational complexity. Tested on this dataset, comparing U-Net, Unet ++ and Attention-U net models for data segmentation results show the C2Ftrans model performs best with the highest dice of 73.5% and the lowest computational complexity.
颞下颌关节紊乱患者最重要的关节异常亚型是不同形式的椎间盘移位和变形。建立有效的下颌关节检测分割模型,以支持颞下颌关节疾病的磁共振诊断是至关重要的。本研究的数据来源于204张关节盘患者的MRI图像以及相应的颞下颌关节MRI分割标签。这些图像被用来评估四种基于深度学习的语义分割方法。采用由粗到精的多尺度结构化C2Ftrans分割模型,将医学图像分割描述为一个由粗到精的过程。该算法能够以较低的计算复杂度进行精确的目标边界分割。在该数据集上进行测试,对比U-Net、Unet ++和Attention-U - net模型的数据分割结果表明,C2Ftrans模型的分割效果最好,分割率最高为73.5%,计算复杂度最低。
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引用次数: 0
Remote Sensing Extraction of Photovoltaic Panels in Desert Areas Based on Feature Optimization 基于特征优化的荒漠地区光伏板遥感提取
Hongyu Zhao, Zhiping Yin
Aiming at the problem of low efficiency of remote sensing imagery for PV (Photovoltaic) panel extraction in desert areas, this paper proposes a remote sensing identification method for PV panels based on the optimization of multi-feature combinations, taking Qinghai province as an example. The research uses the GEE cloud platform to construct a feature set containing topographic features, spectral features and index features, filters the feature set according to the feature importance and recursive elimination idea, and introduces feature correlation analysis to filter the feature set to get the optimal feature combination, and uses random forest RF to achieve PV panel extraction, and designs four experiments to verify the effectiveness of the preferred features. The results show that: the best effect of PV panel extraction is achieved by the random forest algorithm with feature selection, the overall accuracy of classification reaches 95.86%, and the Kappa coefficient reaches 0.9197; and the accuracy of PV panel area extraction for Qinghai province can reach 95.68%; the feature optimization method proposed in this paper can effectively improve the extraction accuracy of PV panels in desert areas.
针对荒漠地区光伏板遥感图像提取效率低的问题,以青海省为例,提出了一种基于多特征组合优化的光伏板遥感识别方法。本研究利用GEE云平台构建包含地形特征、光谱特征和指数特征的特征集,根据特征重要性和递归消去思想对特征集进行滤波,并引入特征关联分析对特征集进行滤波,得到最优特征组合,利用随机森林RF实现光伏面板提取,并设计4个实验验证优选特征的有效性。结果表明:带特征选择的随机森林算法对光伏板的提取效果最好,分类总体准确率达到95.86%,Kappa系数达到0.9197;青海省光伏板面积提取精度可达95.68%;本文提出的特征优化方法可以有效提高沙漠地区光伏板的提取精度。
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引用次数: 0
An Application Of Knowledge Map In Intelligent Education 知识地图在智能教育中的应用
Wang Lintao, Yu Yuanhui, Guo Qisong, Li Xinxin
“Rita” is short for “right teacher AI” which is a learning assistant app developed for college teachers and students, aiming to provide an intelligent platform to assist teachers and students in learning and teaching. The system includes subject content tag graphic database, intelligent article push module, intelligent Q&A module, user service module, etc. This paper studies the structure, classification and application of knowledge map in the field of intelligent education, points out the practical efficacy of knowledge map in mobile teaching assistant system, and establishes a subject tree relationship model, which provides a basis for intelligent recommendation and subject analysis.
“丽塔”是“right teacher AI”的简称,是一款专为高校师生开发的学习助手app,旨在为师生提供一个辅助学习和教学的智能平台。该系统包括主题内容标签图形数据库、智能文章推送模块、智能问答模块、用户服务模块等。本文研究了知识地图的结构、分类及其在智能教育领域的应用,指出了知识地图在移动教学辅助系统中的实际功效,并建立了学科树关系模型,为智能推荐和学科分析提供了依据。
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引用次数: 0
Hurst Exponent Analysis Of Schizophrenia Electroencephalogram Based On Multi-point Fractional Brownian Bridge 基于多点分数布朗桥的精神分裂症脑电图赫斯特指数分析
Congzhou Zhong, Wenpo Yao, Wanyi Yi, Jui-Pin Wang, Dengxuan Bai, Qiong Wang
In this paper, the Hurst index calculation method based on multipoint fractional Brown bridge was used to analyze the electroencephalogram(EEG) of schizophrenia patients and healthy people under the same sound paradigm experiment. We used this method to analyze the short-term EEG signals of the healthy group and the patient group around the time point 100ms after stimulation and found that the method can effectively analyze the Hurst index of short-time series, in the frontal lobe and central area. There were significant differences in passage, and the Hurst index was lower in healthy people than in patients. The results show that in this experiment, the long-term correlation of EEG signals after stimulation in patients with schizophrenia is higher, and the complexity of EEG signals is lower, which can help clinical diagnosis of schizophrenia better. At the same time, this paper compares the Hurst exponent calculation method based on the multi-point fractional Brown bridge with the traditional rescaled range analysis method. The Hurst index calculation of the sequence can analyze the difference between the healthy group and the patient group on a smaller scale.
本文采用基于多点分数布朗桥的Hurst指数计算方法,对精神分裂症患者和正常人在相同声音范式实验条件下的脑电图进行了分析。我们利用该方法对刺激后100ms前后健康组和患者组的短期脑电图信号进行分析,发现该方法能有效分析额叶和中央区短时间序列的Hurst指数。在传代上存在显著差异,健康人群的赫斯特指数低于患者。结果表明,在本实验中,精神分裂症患者刺激后脑电信号的长期相关性较高,脑电信号的复杂性较低,可以更好地帮助精神分裂症的临床诊断。同时,将基于多点分数布朗桥的Hurst指数计算方法与传统的重标差分析方法进行了比较。序列的Hurst指数计算可以在较小的尺度上分析健康组与患者组之间的差异。
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引用次数: 0
Research on the non-contact physiological parameter measurement technology based on imaging photoplethysmography 基于成像光容积脉搏波的非接触式生理参数测量技术研究
Ying Zhu, Dexin Kong, Yumeng Mao, Ying Yu
The background of imaging photoplethysmography (IPPG) is briefly presented from biological and physical perspectives. Taking the optimization of the IPPG signal as the starting point, the effects of external factors and the original signal extraction process are introduced respectively. External factors such as the green light source in the ambient light source have the highest signal-noise ratio (SNR), with No significant effect on light intensity. The lighter the skin color of the human body, the higher the SNR, with gender having no effect. The extraction of the original signal such as the region of interest (ROI) region selects the face T -zone with the highest SNR. The original signals are extracted by the Cg channel in the YCbCr, which is better than other color spaces. Face detection algorithms and tracking algorithms are intended to solve the problem of signal quality degradation caused by small movements, background changes, and missing angles in face video shooting, including the degradation of video quality during transmission. physiological parameters are measured by formula conversion and fitting. At present, there is still a lot of room for the development of this detection technology, and domestic and foreign research should be towards eliminating motion artifacts. Efforts have been made to improve the detection effect in the absence of local information, develop new applications of IPPG detection technology, better process compressed data, and combine daily portable devices with the direction of use.
从生物学和物理学的角度简要介绍了成像光体积脉搏波(IPPG)的背景。以IPPG信号的优化为出发点,分别介绍了外部因素的影响和原始信号的提取过程。环境光源中绿光源等外部因素的信噪比最高,对光强无显著影响。人体肤色越浅,信噪比越高,性别不受影响。对感兴趣区域(ROI)等原始信号的提取,选择信噪比最高的面T区。原始信号由YCbCr中的Cg通道提取,其效果优于其他色彩空间。人脸检测算法和跟踪算法旨在解决人脸视频拍摄中由于微小运动、背景变化、缺角等导致的信号质量下降问题,包括传输过程中的视频质量下降问题。生理参数通过公式转换和拟合得到。目前,该检测技术仍有很大的发展空间,国内外的研究应朝着消除运动伪影的方向发展。提高本地信息缺失情况下的检测效果,开发IPPG检测技术的新应用,更好地处理压缩数据,将日常便携式设备与使用方向结合起来。
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引用次数: 2
Face Recognition with Robust Matrix Factorization 基于鲁棒矩阵分解的人脸识别
Qing Li
In face recognition, we may encounter face images with shadow and illumination, which will affect the recognition. In this scenario, the low-rank matrix and a sparse matrix can be obtained by low-rank matrix decomposition of the collected original face image, where the low-rank matrix is the face image without shadow and illumination. In order to obtain the low-rank matrix, the Sub-gradient method and AIRLS method are used in this paper, and their effects are compared in the experimental verification of Yale face database.
在人脸识别中,我们可能会遇到有阴影和光照的人脸图像,这会影响识别。在这种情况下,对采集到的原始人脸图像进行低秩矩阵分解,得到低秩矩阵和稀疏矩阵,其中低秩矩阵为没有阴影和光照的人脸图像。为了获得低秩矩阵,本文采用了亚梯度法和AIRLS法,并在耶鲁人脸数据库的实验验证中比较了它们的效果。
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引用次数: 0
An Optical Guidance Method for Robotic Intramuscular Injection System 一种用于机器人肌肉注射系统的光学制导方法
Yunlong Zhu, Wenlong Zhang, Biao Yan, Rongqian Yang
Intramuscular (IM) injection is mainly performed manually at present. Large-scale COVID-19 vaccination has exposed various problems of manual IM injection. In addition, the clinical success rate of manual IM injection is also unsatisfactory. Using robotic intramuscular injection system (RIMIS) is expected to realize automated vaccination and improve the success rate of IM injection. The existing robotic needle insertion system based on image guidance is not a practical option for IM injection because of the time-consuming medical imaging process. In this paper, an optical guidance method for RIMIS is proposed, which uses near-infrared optical tracking system and retro-reflective patch to achieve rapid acquisition of surface normal vector. A closed loop formed by six coordinate systems is used to realize the accurate control of the injection angle and depth. Experimental results show that the RIMIS based on the proposed method can complete the simulated IM injection operation without image guidance and possess accurate control of the injection angle and depth.
肌内注射目前主要是手工进行的。COVID-19大规模疫苗接种暴露了人工注射IM的各种问题。此外,手工注射IM的临床成功率也不理想。利用机器人肌肉注射系统(RIMIS)有望实现自动化疫苗接种,提高IM注射的成功率。现有的基于图像引导的机器人插针系统由于耗时的医学成像过程而不是IM注射的实际选择。本文提出了一种利用近红外光学跟踪系统和反反射贴片实现表面法向量快速获取的RIMIS光学制导方法。采用6个坐标系组成闭环,实现了喷射角度和深度的精确控制。实验结果表明,基于该方法的RIMIS可以在没有图像引导的情况下完成模拟的IM注射操作,并具有精确的注射角度和注射深度控制。
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引用次数: 0
期刊
2022 15th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI)
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