{"title":"Abstract of the Scientific Literature.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 6","pages":"399"},"PeriodicalIF":1.6,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9197602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burton L Edelstein, Tener Huang, Caroline J Greco, Isa Rodriguez
Purpose: The purpose of this study was to identify and analyze reports and testimonies from the U.S. Government Accountability Office (GAO) relevant to children's oral health and dental care during the calendar years 1990 through 2021. Methods: The GAO database was searched for reports and testimonies that directly or tangentially addressed children's oral health and dental care. Titles, abstracts, and texts were reviewed to determine what Congress asked of GAO and how GAO responded. Results: Among nearly 30,000 health- and health care-related GAO releases over 31 years, 35 were focused on children's oral health and/or dental care. In response to requests by key congressional committees and legislators, reports addressed coverage, access, utilization, cost, network adequacy, workforce, and safety net. Multiple reports addressed the persistence of health and health care inequities. GAO's findings have supported dental mandates for the Children's Health Insurance Program (CHIP) and Affordable Care Act, the federal pediatric Oral Health Initiative, and congressional oversight of federal agencies that administer Medicaid/CHIP and train dentists. Conclusions: Over more than a quarter century, the U. S. Government Accountability Office has contributed meaningfully to congressional understanding of pediatric oral health and dental care. Continued reliance by Congress on GAO investigations can further enhance policy-making and oversight on issues important to pediatric dentistry.
目的:本研究的目的是确定和分析美国政府问责局(GAO)在1990年至2021年期间与儿童口腔健康和牙齿保健相关的报告和证词。方法:检索政府问责局数据库中直接或间接涉及儿童口腔健康和牙齿保健的报告和证词。对标题、摘要和文本进行了审查,以确定国会向政府问责局提出了什么要求以及政府问责局如何回应。结果:在过去31年中,近30,000份与健康和医疗保健相关的GAO报告中,有35份侧重于儿童口腔健康和/或牙科保健。根据主要国会委员会和立法者的要求,报告涉及覆盖范围、访问、利用、成本、网络充分性、劳动力和安全网。多份报告讨论了持续存在的卫生和保健不平等现象。政府问责局的调查结果支持了《儿童健康保险计划》(CHIP)和《平价医疗法案》(Affordable Care Act)、联邦儿童口腔健康倡议、以及国会对管理医疗补助/CHIP和培训牙医的联邦机构的监督。结论:在超过25年的时间里,美国政府问责局对国会对儿童口腔健康和牙齿护理的理解做出了有意义的贡献。国会对政府问责局调查的持续依赖可以进一步加强对儿童牙科重要问题的决策和监督。
{"title":"U.S. Government Accountability Office Reports on Children's Oral Health and Dental Care: A 31-Year Retrospective Analysis.","authors":"Burton L Edelstein, Tener Huang, Caroline J Greco, Isa Rodriguez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to identify and analyze reports and testimonies from the U.S. Government Accountability Office (GAO) relevant to children's oral health and dental care during the calendar years 1990 through 2021. <b>Methods:</b> The GAO database was searched for reports and testimonies that directly or tangentially addressed children's oral health and dental care. Titles, abstracts, and texts were reviewed to determine what Congress asked of GAO and how GAO responded. <b>Results:</b> Among nearly 30,000 health- and health care-related GAO releases over 31 years, 35 were focused on children's oral health and/or dental care. In response to requests by key congressional committees and legislators, reports addressed coverage, access, utilization, cost, network adequacy, workforce, and safety net. Multiple reports addressed the persistence of health and health care inequities. GAO's findings have supported dental mandates for the Children's Health Insurance Program (CHIP) and Affordable Care Act, the federal pediatric Oral Health Initiative, and congressional oversight of federal agencies that administer Medicaid/CHIP and train dentists. <b>Conclusions:</b> Over more than a quarter century, the U. S. Government Accountability Office has contributed meaningfully to congressional understanding of pediatric oral health and dental care. Continued reliance by Congress on GAO investigations can further enhance policy-making and oversight on issues important to pediatric dentistry.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 6","pages":"404-410"},"PeriodicalIF":1.6,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9166668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula D Portella, Bruna C Dias, Patricia Ferreira, Juliana F de Souza, Leticia Wambier, Luciana Reichert da Silva Assunção
Purpose: Assess whether children with developmental defects of enamel (DDE) in primary teeth have a higher risk of having dental caries or a higher prevalence of clinical consequences due to the disease than those without DDE. Methods: Search was performed in PubMed, Scopus, Web of Science™, Cochrane Library, LILACS, BBO, Embase databases and in gray literature. Three independent reviewers were involved in study selection, data extraction, and bias assessment. Risk of bias was evaluated by the Newcastle-Ottawa scale. DDE and its subtypes (demarcated opacities, hypoplasia, hypomineralized second primary molars (HSPM), and fluorosis) were regarded as exposure. Dental caries and clinical consequences of untreated caries were also assessed. In the meta-analyses, odds ratio (OR) was used in the random effects model for dichotomous outcomes. Quality of evidence was assessed using the Grading Recommendations Assessment, Development and Evaluation (GRADE). Results: The search yielded 5,750 studies, 39 of which were included in the systematic review and 20 in the meta-analysis. The risk of bias ranged from 4 to 9 points. Children with DDE were more prone to primary tooth caries (OR=2.79; 95% CI:1.29-6.03), and so were those with demarcated opacities (OR=1.75; 95% CI:1.09-2.78), hypoplasia (OR=2.84; 95% CI:1.73-4.67), and HSPM (OR=2.89; 95% CI:1.65-5.06). Fluorosis was not associated with caries (OR=1.39; 95% CI:0.97-1.98). Regarding tooth as a unit of analysis, DDE was highly associated with caries (OR=2.34; 95% CI:1.74-3.16). As for the clinical consequences of caries, only the qualitative analysis was conducted and there was no consensus in the studies. Conclusion: DDE is associated with higher primary tooth caries experience.
目的:评估患有乳牙牙釉质发育缺陷(DDE)的儿童是否比没有DDE的儿童有更高的患龋风险或更高的临床后果发生率。方法:检索PubMed、Scopus、Web of Science™、Cochrane Library、LILACS、BBO、Embase数据库和灰色文献。研究选择、数据提取和偏倚评估均由三名独立审稿人参与。偏倚风险采用纽卡斯尔-渥太华量表进行评估。DDE及其亚型(有界混浊、发育不全、第二乳牙低矿化和氟中毒)被认为是暴露。龋齿和未经治疗的龋齿的临床后果也进行了评估。在荟萃分析中,采用优势比(OR)作为二分类结果的随机效应模型。使用分级建议评估、发展和评价(GRADE)来评估证据质量。结果:检索结果为5750项研究,其中39项纳入系统综述,20项纳入荟萃分析。偏倚风险从4到9分不等。DDE患儿更容易患乳牙龋(OR=2.79;95% CI:1.29-6.03),界限模糊的患者也是如此(OR=1.75;95% CI:1.09-2.78),发育不全(OR=2.84;95% CI:1.73-4.67)和HSPM (OR=2.89;95%置信区间:1.65—-5.06)。氟中毒与龋齿无关(OR=1.39;95%置信区间:0.97—-1.98)。以牙齿为分析单位,DDE与龋齿高度相关(OR=2.34;95%置信区间:1.74—-3.16)。对于龋齿的临床后果,研究只进行了定性分析,尚无共识。结论:DDE与乳牙高龋率相关。
{"title":"The Association of Developmental Dental Defects and the Clinical Consequences in the Primary Dentition: A Systematic Review of Observational Studies.","authors":"Paula D Portella, Bruna C Dias, Patricia Ferreira, Juliana F de Souza, Leticia Wambier, Luciana Reichert da Silva Assunção","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> Assess whether children with developmental defects of enamel (DDE) in primary teeth have a higher risk of having dental caries or a higher prevalence of clinical consequences due to the disease than those without DDE. <b>Methods:</b> Search was performed in PubMed, Scopus, Web of Science™, Cochrane Library, LILACS, BBO, Embase databases and in gray literature. Three independent reviewers were involved in study selection, data extraction, and bias assessment. Risk of bias was evaluated by the Newcastle-Ottawa scale. DDE and its subtypes (demarcated opacities, hypoplasia, hypomineralized second primary molars (HSPM), and fluorosis) were regarded as exposure. Dental caries and clinical consequences of untreated caries were also assessed. In the meta-analyses, odds ratio (OR) was used in the random effects model for dichotomous outcomes. Quality of evidence was assessed using the Grading Recommendations Assessment, Development and Evaluation (GRADE). <b>Results:</b> The search yielded 5,750 studies, 39 of which were included in the systematic review and 20 in the meta-analysis. The risk of bias ranged from 4 to 9 points. Children with DDE were more prone to primary tooth caries (OR=2.79; 95% CI:1.29-6.03), and so were those with demarcated opacities (OR=1.75; 95% CI:1.09-2.78), hypoplasia (OR=2.84; 95% CI:1.73-4.67), and HSPM (OR=2.89; 95% CI:1.65-5.06). Fluorosis was not associated with caries (OR=1.39; 95% CI:0.97-1.98). Regarding tooth as a unit of analysis, DDE was highly associated with caries (OR=2.34; 95% CI:1.74-3.16). As for the clinical consequences of caries, only the qualitative analysis was conducted and there was no consensus in the studies. <b>Conclusion:</b> DDE is associated with higher primary tooth caries experience.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 5","pages":"330-341"},"PeriodicalIF":1.6,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10446341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The purpose of this study was to report the prevalence of early childhood caries (ECC) and severe early childhood caries (S-ECC) in the United States and to examine trends from 2013 to 2018 in children under six years of age. Methods: Data were obtained from National Health and Nutrition Examination Survey (NHANES). Data from three consecutive cycles (2013 to 2014, 2015 to 2016, and 2017 to 2018) were analyzed. A total of 3,157 children younger than six years of age were included in the analysis. The proportion of children with ECC who developed S-ECC was calculated to assess the severity of the disease burden. Multivariable logistic models were used to determine the significance of both linear and quadratic trends. Subgroup analyses were done to test trends in different population groups. Results: The overall prevalence of ECC from 2013 to 2018 was 18.6 percent; the overall prevalence of S-ECC during this interval was 10.6 percent. The prevalence of ECC decreased from 2013 to 2014 (19.6 percent) to 2015 to 2016 (17.4 percent) but increased from 2017 to 2018 (to 18.7 percent). By contrast, the prevalence of S-ECC increased substantially from 2013 to 2014 (9.8 percent) through 2017 to 2018 (11.9 percent). The proportion of children with S-ECC among those with ECC increased from 2013 (49.9 percent) to 2018 (63.4 percent; linear P=0.048) with a significant linear increase among five-year- old (P=0.013), males (P=0.037) and children in families with income 100 percent of the Federal Poverty Guideline (P=0.003). Conclusion: A greater proportion of children with early childhood caries developed from 2017 to 2018 versus 2013 to 2014.
{"title":"Prevalence, Trends, and Severity of Early Childhood Caries in The United States: National Health and Nutritional Examination Survey Data 2013 to 2018.","authors":"Anusha Kotha, Abhilash Vemulapalli, Surendra Reddy Mandapati, Subhash Aryal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to report the prevalence of early childhood caries (ECC) and severe early childhood caries (S-ECC) in the United States and to examine trends from 2013 to 2018 in children under six years of age. <b>Methods:</b> Data were obtained from National Health and Nutrition Examination Survey (NHANES). Data from three consecutive cycles (2013 to 2014, 2015 to 2016, and 2017 to 2018) were analyzed. A total of 3,157 children younger than six years of age were included in the analysis. The proportion of children with ECC who developed S-ECC was calculated to assess the severity of the disease burden. Multivariable logistic models were used to determine the significance of both linear and quadratic trends. Subgroup analyses were done to test trends in different population groups. <b>Results:</b> The overall prevalence of ECC from 2013 to 2018 was 18.6 percent; the overall prevalence of S-ECC during this interval was 10.6 percent. The prevalence of ECC decreased from 2013 to 2014 (19.6 percent) to 2015 to 2016 (17.4 percent) but increased from 2017 to 2018 (to 18.7 percent). By contrast, the prevalence of S-ECC increased substantially from 2013 to 2014 (9.8 percent) through 2017 to 2018 (11.9 percent). The proportion of children with S-ECC among those with ECC increased from 2013 (49.9 percent) to 2018 (63.4 percent; linear P=0.048) with a significant linear increase among five-year- old (P=0.013), males (P=0.037) and children in families with income 100 percent of the Federal Poverty Guideline (P=0.003). <b>Conclusion:</b> A greater proportion of children with early childhood caries developed from 2017 to 2018 versus 2013 to 2014.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 4","pages":"261-268"},"PeriodicalIF":1.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40721007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yazeed Magbul Althomali, Sabri Musa, Nor Malina Manan, Nor Azlida Mohd Nor
Purpose: The purpose of this study was to evaluate the clinical retention capabilities of a self-etch adhesive system (experimental group) and conventional acid-etch (control group) techniques and compare the caries incidence within six months and 24 months of follow-up periods. Methods: A total of 47 healthy children with a mean age of 9.7 years and either sound or noncavitated erupted permanent first molars were included in the trial. A total of 188 molars were randomly assigned in a split-mouth design for the self-etch mode in the universal adhesive or conventional acid-etch. Differences in sealant retention and caries incidence were compared at six and 24 months after sealant placement using a chi-square test. Results: Within 24 months of follow-up, the retention of fissure sealant applied using conventional acid etching (41 out of 66; 62.1 percent) was significantly higher (P<0.05) than that of the fissure sealant applied using self-etching mode in the universal adhesive system (17 out of 66; 25.8 percent). There was no significant difference in caries incidence between the two groups up to 24 months after sealant placement. Conclusion: With 24 months of follow-up, the retention of the conventional acid-etching technique were superior to those of the self-etch technique.
{"title":"Retention Evaluation of Fissure Sealants Applied Using Self-Etch and Conventional Acid-Etch Techniques: A Randomized Control Trial Among Schoolchildren.","authors":"Yazeed Magbul Althomali, Sabri Musa, Nor Malina Manan, Nor Azlida Mohd Nor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to evaluate the clinical retention capabilities of a self-etch adhesive system (experimental group) and conventional acid-etch (control group) techniques and compare the caries incidence within six months and 24 months of follow-up periods. <b>Methods:</b> A total of 47 healthy children with a mean age of 9.7 years and either sound or noncavitated erupted permanent first molars were included in the trial. A total of 188 molars were randomly assigned in a split-mouth design for the self-etch mode in the universal adhesive or conventional acid-etch. Differences in sealant retention and caries incidence were compared at six and 24 months after sealant placement using a chi-square test. <b>Results:</b> Within 24 months of follow-up, the retention of fissure sealant applied using conventional acid etching (41 out of 66; 62.1 percent) was significantly higher (P<0.05) than that of the fissure sealant applied using self-etching mode in the universal adhesive system (17 out of 66; 25.8 percent). There was no significant difference in caries incidence between the two groups up to 24 months after sealant placement. <b>Conclusion:</b> With 24 months of follow-up, the retention of the conventional acid-etching technique were superior to those of the self-etch technique.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 4","pages":"249-254"},"PeriodicalIF":1.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40721008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The purpose of this study was to evaluate the association between probable awake bruxism (PAB) and school bullying in children and adolescents. Methods: A total of 380 children and adolescents enrolled in public and private schools in the city of Lavras, Minas Gerais, Brazil, participated in this case-control study. The case group (190 children with PAB) and the control group (190 children without PAB) were matched for sex and age. Data acquisition involved questionnaires administered to the children/adolescents and their parents/caregivers. An oral clinical examination to assess attrition tooth wear was also performed. Descriptive statistics and logistic regression analyses (95 percent confidence interval [95% CI], P<0.05) were conducted. Results: Among the 380 participants, 176 (46.3 percent) were male and 204 (53.7 percent) were female. Children and adolescents who were involved in bullying episodes as victims/bullies (odds ratio [OR] equals 2.92, 95% CI equals 1.07 to 7.95, P=0.036) and victims (OR equals 1.93, 95% CI equals 1.04 to 3.57, P=0.037) were significantly associated with PAB. Children and adolescents who reported sleep problems (OR equals 2.51, 95% CI equals 1.07 to 5.89, P=0.033) were significantly associated with PAB. Conclusion: Based on the results, it was observed that probable awake bruxism is associated with involvement in episodes of school bullying and sleep problems.
目的:本研究的目的是评估儿童和青少年可能的清醒磨牙症(PAB)与学校欺凌之间的关系。方法:共有380名在巴西米纳斯吉拉斯州拉夫拉斯市公立和私立学校就读的儿童和青少年参与了这项病例对照研究。病例组(190例PAB患儿)和对照组(190例无PAB患儿)按性别和年龄进行匹配。数据收集包括向儿童/青少年及其父母/照顾者发放问卷。同时进行口腔临床检查以评估磨耗性牙齿磨损。描述性统计和逻辑回归分析(95%可信区间[95% CI])结果:380名参与者中,176名(46.3%)为男性,204名(53.7%)为女性。作为受害者/欺凌者参与欺凌事件的儿童和青少年(比值比[OR] = 2.92, 95% CI = 1.07至7.95,P=0.036)和受害者(OR = 1.93, 95% CI = 1.04至3.57,P=0.037)与PAB显著相关。报告睡眠问题的儿童和青少年(OR = 2.51, 95% CI = 1.07至5.89,P=0.033)与PAB显著相关。结论:基于结果,我们观察到可能的醒时磨牙症与学校欺凌事件和睡眠问题有关。
{"title":"Association Between Probable Awake Bruxism and School Bullying in Children and Adolescents: A Case-Control Study.","authors":"Isabela Melo Martins, Miriam Pimenta Vale, Letícia Silva Alonso, Lucas Guimarães Abreu, Luciana Fonseca Pádua Gonçalves Tourino, Júnia Maria Cheib Serra-Negra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to evaluate the association between probable awake bruxism (PAB) and school bullying in children and adolescents. <b>Methods:</b> A total of 380 children and adolescents enrolled in public and private schools in the city of Lavras, Minas Gerais, Brazil, participated in this case-control study. The case group (190 children with PAB) and the control group (190 children without PAB) were matched for sex and age. Data acquisition involved questionnaires administered to the children/adolescents and their parents/caregivers. An oral clinical examination to assess attrition tooth wear was also performed. Descriptive statistics and logistic regression analyses (95 percent confidence interval [95% CI], P<0.05) were conducted. <b>Results:</b> Among the 380 participants, 176 (46.3 percent) were male and 204 (53.7 percent) were female. Children and adolescents who were involved in bullying episodes as victims/bullies (odds ratio [OR] equals 2.92, 95% CI equals 1.07 to 7.95, P=0.036) and victims (OR equals 1.93, 95% CI equals 1.04 to 3.57, P=0.037) were significantly associated with PAB. Children and adolescents who reported sleep problems (OR equals 2.51, 95% CI equals 1.07 to 5.89, P=0.033) were significantly associated with PAB. <b>Conclusion:</b> Based on the results, it was observed that probable awake bruxism is associated with involvement in episodes of school bullying and sleep problems.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 4","pages":"284-289"},"PeriodicalIF":1.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40721005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leveraging Policy to Promote Pediatric Oral Health Equity.","authors":"Burton L Edelstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 4","pages":"246-247"},"PeriodicalIF":1.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40721009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roaa I Alhaidari, Maha AlSarheed, Saad A Sheta, Mohammed Aldhubaiban
Purpose: The purpose of this study was to compare the effectiveness of intranasal fentanyl combined with oral midazolam to oral midazolam alone in pediatric dental patients. Methods: Thirty-two uncooperative healthy children aged three to six years old, who met the inclusion criteria, were randomly assigned to receive oral midazolam (0.7 mg/kg) with either intranasal fentanyl (one μg/kg) or intranasal placebo (saline). A controlled, randomized, double-blinded, crossover clinical trial design was followed so that each child received both regimens. Data collected included the onset of sedation, working time, sedation and behavior assessment, and occurrence of side effects. Results: The onset of sedation time was not statistically different between the two groups (P=0.62), while the median working time of the midazolam/fentanyl sedation was sig- nificantly longer than the midazolam sedation (P<0.001). Sedation scores were significantly better with the midazolam/fentanyl sedation regimen at separation from parents (P=0.032), local anesthesia administration (P=0.018), rubber dam application (P=0.035), after five minutes of dental treatment (P=0.035), after 10 minutes (P=0.039), after 15 minutes (P=0.012), and after 20 minutes (P=0.038). Behavior scores were significantly better with the midazolam/fentanyl sedation only at local anesthesia administration (P=0.021), rubber dam placement (P=0.004), and after five minutes of dental treatment (P=0.049). Minor side effects occurred in 12.5 percent of sedation procedures and were not significantly associated with either of the two groups (P=0.70). Conclusion: The combination of oral midazolam with intranasal fentanyl sedation, when compared to oral midazolamas a single agent, significantly improved sedation and behavior during local anesthesia and operative dentistry for healthy three- to six-year-old children in addition to prolonged sedation working time.
{"title":"Intranasal Fentanyl Combined with Oral Midazolam for Pediatric Dental Sedation: A Controlled Randomized Blinded Crossover Clinical Trial.","authors":"Roaa I Alhaidari, Maha AlSarheed, Saad A Sheta, Mohammed Aldhubaiban","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to compare the effectiveness of intranasal fentanyl combined with oral midazolam to oral midazolam alone in pediatric dental patients. <b>Methods:</b> Thirty-two uncooperative healthy children aged three to six years old, who met the inclusion criteria, were randomly assigned to receive oral midazolam (0.7 mg/kg) with either intranasal fentanyl (one μg/kg) or intranasal placebo (saline). A controlled, randomized, double-blinded, crossover clinical trial design was followed so that each child received both regimens. Data collected included the onset of sedation, working time, sedation and behavior assessment, and occurrence of side effects. <b>Results:</b> The onset of sedation time was not statistically different between the two groups (P=0.62), while the median working time of the midazolam/fentanyl sedation was sig- nificantly longer than the midazolam sedation (P<0.001). Sedation scores were significantly better with the midazolam/fentanyl sedation regimen at separation from parents (P=0.032), local anesthesia administration (P=0.018), rubber dam application (P=0.035), after five minutes of dental treatment (P=0.035), after 10 minutes (P=0.039), after 15 minutes (P=0.012), and after 20 minutes (P=0.038). Behavior scores were significantly better with the midazolam/fentanyl sedation only at local anesthesia administration (P=0.021), rubber dam placement (P=0.004), and after five minutes of dental treatment (P=0.049). Minor side effects occurred in 12.5 percent of sedation procedures and were not significantly associated with either of the two groups (P=0.70). <b>Conclusion:</b> The combination of oral midazolam with intranasal fentanyl sedation, when compared to oral midazolamas a single agent, significantly improved sedation and behavior during local anesthesia and operative dentistry for healthy three- to six-year-old children in addition to prolonged sedation working time.</p>","PeriodicalId":19863,"journal":{"name":"Pediatric dentistry","volume":"44 4","pages":"255-260"},"PeriodicalIF":1.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40721004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}